Surface functionalization for spore-based biosensors with organosilanes
- In the present work, surface functionalization of different sensor materials was studied. Organosilanes are well known to serve as coupling agent for biomolecules or cells on inorganic materials. 3-aminopropyltriethoxysilane (APTES) was used to attach microbiological spores time to an interdigitated sensor surface. The functionality and physical properties of APTES were studied on isolated sensor materials, namely silicon dioxide (SiO2) and platinum (Pt) as well as the combined material on sensor level. A predominant immobilization of spores could be demonstrated on SiO2 surfaces. Additionally, the impedance signal of APTES-functionalized biosensor chips has been investigated.
| Author: | Julio Arreola, Jan OberländerORCiD, M. Mätzkow, Michael Keusgen, Michael Josef SchöningORCiD |
|---|---|
| DOI: | https://doi.org/10.1016/j.electacta.2017.04.157 |
| ISSN: | 0013-4686 |
| Parent Title (English): | Electrochimica Acta |
| Publisher: | Elsevier |
| Place of publication: | Amsterdam |
| Document Type: | Article |
| Language: | English |
| Year of Completion: | 2017 |
| Date of the Publication (Server): | 2017/05/04 |
| Volume: | 241 |
| First Page: | 237 |
| Last Page: | 243 |
| Link: | https://doi.org/10.1016/j.electacta.2017.04.157 |
| Zugriffsart: | campus |
| Institutes: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
| FH Aachen / INB - Institut für Nano- und Biotechnologien | |
| collections: | Verlag / Elsevier |
