TY  - JOUR
A1  - Adels, Klaudia
A1  - Monakhova, Yulia
T1  - Low-field NMR spectroscopic study of e-cigarettes: Is determination of only nicotine and organic carrier solvents possible?
T2  - Microchemical Journal
N2  - Electronic cigarettes (e-cigarettes) have become popular worldwide with the market growing exponentially in some countries. The absence of product standards and safety regulations requires urgent development of analytical methodologies for the holistic control of the growing diversity of such products. An approach based on low-field nuclear magnetic resonance (LF-NMR) at 80 MHz is presented for the simultaneous determination of key parameters: carrier solvents (vegetable glycerine (VG), propylene glycol (PG) and water), total nicotine as well as free-base nicotine fraction. Moreover, qualitative and quantitative determination of fourteen weak organic acids deliberately added to enhance sensory characteristics of e-cigarettes was possible. In most cases these parameters can be rapidly and conveniently determined without using any sample manipulation such as dilution, extraction or derivatization steps. The method was applied for 37 authentic e-cigarettes samples. In particular, eight different organic acids with the content up to 56 mg/mL were detected. Due to its simplicity, the method can be used in routine regulatory control as well as to study release behaviour of nicotine and other e-cigarettes constituents in different products.
KW  - Electronic cigarettes
KW  - Low field NMR
KW  - Carrier solvents
KW  - Free-base nicotine
KW  - Weak organic acids
Y1  - 2024
UR  - https://opus.bibliothek.fh-aachen.de/opus4/frontdoor/index/index/docId/11167
SN  - 1095-9149
N1  - Corresponding author: Yulia Monakhova
VL  - 203
PB  - Elsevier
CY  - Amsterdam
ER  -