TY  - JOUR
A1  - von Knobelsdorf-Brenkenhoff, Florian
A1  - Frauenrath, Tobias
A1  - Prothmann, Marcel
A1  - Dieringer, Matthias A.
A1  - Hezel, Fabian
A1  - Renz, Wolfgang
A1  - Kretschel, Kerstin
A1  - Niendorf, Thoralf
A1  - Schulz-Menger, Jeanette
T1  - Cardiac chamber quantification using magnetic resonance imaging at 7 Tesla—a pilot study
N2  - Objectives
Interest in cardiovascular magnetic resonance (CMR) at 7 T is motivated by the expected increase in spatial and temporal resolution, but the method is technically challenging. We examined the feasibility of cardiac chamber quantification at 7 T.

Methods
A stack of short axes covering the left ventricle was obtained in nine healthy male volunteers. At 1.5 T, steady-state free precession (SSFP) and fast gradient echo (FGRE) cine imaging with 7 mm slice thickness (STH) were used. At 7 T, FGRE with 7 mm and 4 mm STH were applied. End-diastolic volume, end-systolic volume, ejection fraction and mass were calculated.

Results
All 7 T examinations provided excellent blood/myocardium contrast for all slice directions. No significant difference was found regarding ejection fraction and cardiac volumes between SSFP at 1.5 T and FGRE at 7 T, while volumes obtained from FGRE at 1.5 T were underestimated. Cardiac mass derived from FGRE at 1.5 and 7 T was larger than obtained from SSFP at 1.5 T. Agreement of volumes and mass between SSFP at 1.5 T and FGRE improved for FGRE at 7 T when combined with an STH reduction to 4 mm.

Conclusions
This pilot study demonstrates that cardiac chamber quantification at 7 T using FGRE is feasible and agrees closely with SSFP at 1.5 T.
Y1  - 2024
UR  - https://opus.bibliothek.fh-aachen.de/opus4/frontdoor/index/index/docId/11300
SN  - 0938-7994
VL  - 20
SP  - 2844
EP  - 2852
PB  - Springer
CY  - Berlin, Heidelberg
ER  -