TY  - JOUR
A1  - Albanna, Walid
A1  - Conzen, Catharina
A1  - Weiss, Miriam
A1  - Seyfried, Katharina
A1  - Kotliar, Konstantin
A1  - Schmidt, Tobias Philip
A1  - Kuerten, David
A1  - Hescheler, Jürgen
A1  - Bruecken, Anne
A1  - Schmidt-Trucksäss, Arno
A1  - Neumaier, Felix
A1  - Wiesmann, Martin
A1  - Clusmann, Hans
A1  - Schubert, Gerrit Alexander
T1  - Non-invasive assessment of neurovascular coupling after aneurysmal subarachnoid hemorrhage: a prospective observational trial using retinal vessel analysis
T2  - Frontiers in Neurology
N2  - Delayed cerebral ischemia (DCI) is a common complication after aneurysmal subarachnoid hemorrhage (aSAH) and can lead to infarction and poor clinical outcome. The underlying mechanisms are still incompletely understood, but animal models indicate that vasoactive metabolites and inflammatory cytokines produced within the subarachnoid space may progressively impair and partially invert neurovascular coupling (NVC) in the brain. Because cerebral and retinal microvasculature are governed by comparable regulatory mechanisms and may be connected by perivascular pathways, retinal vascular changes are increasingly recognized as a potential surrogate for altered NVC in the brain. Here, we used non-invasive retinal vessel analysis (RVA) to assess microvascular function in aSAH patients at different times after the ictus.
Y1  - 2021
UR  - https://opus.bibliothek.fh-aachen.de/opus4/frontdoor/index/index/docId/9791
SN  - 1664-2295
VL  - 12
IS  - 12
SP  - 1
EP  - 15
ER  -