@article{JanusAchtsnichtDrinicetal.2023, author = {Janus, Kevin Alexander and Achtsnicht, Stefan and Drinic, Aleksander and Kopp, Alexander and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Transient magnesium-based thin-film temperature sensor on a flexible, bioabsorbable substrate for future medical applications}, series = {Applied Research}, journal = {Applied Research}, number = {Accepted manuscript}, publisher = {Wiley-VCH}, issn = {2702-4288 (Print)}, doi = {10.1002/appl.202300102}, pages = {22 Seiten}, year = {2023}, abstract = {In this work, the bioabsorbable materials, namely fibroin, polylactide acid (PLA), magnesium and magnesium oxide are investigated for their application as transient, resistive temperature detectors (RTD). For this purpose, a thin-film magnesium-based meander-like electrode is deposited onto a flexible, bioabsorbable substrate (fibroin or PLA) and encapsulated (passivated) by additional magnesium oxide layers on top and below the magnesium-based electrode. The morphology of different layered RTDs is analyzed by scanning electron microscopy. The sensor performance and lifetime of the RTD is characterized both under ambient atmospheric conditions between 30°C and 43°C, and wet tissue-like conditions with a constant temperature regime of 37°C. The latter triggers the degradation process of the magnesium-based layers. The 3-layers RTDs on a PLA substrate could achieve a lifetime of 8.5 h. These sensors also show the best sensor performance under ambient atmospheric conditions with a mean sensitivity of 0.48 Ω/°C ± 0.01 Ω/°C.}, language = {en} } @inproceedings{HeerRedkowitzKraft2008, author = {Heer, Thomas and Redkowitz, Daniel and Kraft, Bodo}, title = {Tool Support for the Integration of Light-Weight Ontologies}, isbn = {978-3-642-00670-8}, year = {2008}, abstract = {Abstract of the authors: In many areas of computer science ontologies become more and more important. The use of ontologies for domain modeling often brings up the issue of ontology integration. The task of merging several ontologies, covering specific subdomains, into one united ontology has to be solved. Many approaches for ontology integration aim at automating the process of ontology alignment. However, a complete automation is not feasible, and user interaction is always required. Nevertheless, most ontology integration tools offer only very limited support for the interactive part of the integration process. In this paper, we present a novel approach for the interactive integration of ontologies. The result of the ontology integration is incrementally updated after each definition of a correspondence between ontology elements. The user is guided through the ontologies to be integrated. By restricting the possible user actions, the integrity of all defined correspondences is ensured by the tool we developed. We evaluated our tool by integrating different regulations concerning building design.}, subject = {Ontologie }, language = {de} } @article{MolinnusJanusFangetal.2022, author = {Molinnus, Denise and Janus, Kevin Alexander and Fang, Anyelina C. and Drinic, Aleksander and Achtsnicht, Stefan and K{\"o}pf, Marius and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Thick-film carbon electrode deposited onto a biodegradable fibroin substrate for biosensing applications}, series = {Physica status solidi (a)}, volume = {219}, journal = {Physica status solidi (a)}, number = {23}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.202200100}, pages = {1 -- 9}, year = {2022}, abstract = {This study addresses a proof-of-concept experiment with a biocompatible screen-printed carbon electrode deposited onto a biocompatible and biodegradable substrate, which is made of fibroin, a protein derived from silk of the Bombyx mori silkworm. To demonstrate the sensor performance, the carbon electrode is functionalized as a glucose biosensor with the enzyme glucose oxidase and encapsulated with a silicone rubber to ensure biocompatibility of the contact wires. The carbon electrode is fabricated by means of thick-film technology including a curing step to solidify the carbon paste. The influence of the curing temperature and curing time on the electrode morphology is analyzed via scanning electron microscopy. The electrochemical characterization of the glucose biosensor is performed by amperometric/voltammetric measurements of different glucose concentrations in phosphate buffer. Herein, systematic studies at applied potentials from 500 to 1200 mV to the carbon working electrode (vs the Ag/AgCl reference electrode) allow to determine the optimal working potential. Additionally, the influence of the curing parameters on the glucose sensitivity is examined over a time period of up to 361 days. The sensor shows a negligible cross-sensitivity toward ascorbic acid, noradrenaline, and adrenaline. The developed biocompatible biosensor is highly promising for future in vivo and epidermal applications.}, language = {en} } @article{ZhubanovaDigelNojimaetal.2007, author = {Zhubanova, Azhar A. and Digel, Ilya and Nojima, H. and Artmann, Gerhard}, title = {The use of bactericidal effects of cluster ions generated by plasma in medical biotechnology}, year = {2007}, abstract = {The most of conventional methods of air purification use the power of a fan to draw in air and pass it through a filter. The problem of bacterial contamination of inner parts of such a type of air conditioners in some cases draws attention towards alternative air-cleaning systems. Some manufacturers offer to use the ozone's bactericidal and deodorizing effects, but the wide spreading of such systems is restricted by the fact that toxic effects of ozone in respect of human beings are well known. In 2000 Sharp Inc. introduced "Plasma Cluster Ions (PCI)" air purification technology, which uses plasma discharge to generate cluster ions (I 0-14 ). This technology has been developed for those customers that are conscious about health and hygiene. In our experiments, we focused on some principal aspects of plasma-generated ions application - time-dependency and irreversibility of bactericidal action, spatial and kinetic characteristics of emitted cluster particles, their chemical targets in the microbial cells.}, subject = {Clusterion}, language = {en} } @inproceedings{MansurovZhubanovaDigeletal.2008, author = {Mansurov, Zulkhair and Zhubanova, Azhar A. and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Savitskaja, Irina S. and Kozhalakova, A. A. and Kistaubaeva, Aida S.}, title = {The sorption of LPS toxic shock by nanoparticles on base of carbonized vegetable raw materials}, year = {2008}, abstract = {Immobilization of lactobacillus on high temperature carbonizated vegetable raw material (rice husk, grape stones) increases their physiological activity and the quantity of the antibacterial metabolits, that consequently lead to increase of the antagonistic activity of lactobacillus. It is implies that the use of the nanosorbents for the attachment of the probiotical microorganisms are highly perspective for decision the important problems, such as the probiotical preparations delivery to the right address and their attachment to intestines mucosa with the following detoxication of gastro-intestinal tract and the normalization of it's microecology. Besides that, thus, the received carbonizated nanoparticles have peculiar properties - ability to sorption of LPS toxical shock and, hence, to the detoxication of LPS.}, subject = {Kohlenstofffaser}, language = {en} } @inproceedings{StaatHeitzer2002, author = {Staat, Manfred and Heitzer, Michael}, title = {The restricted influence of kinematic hardening on shakedown loads}, year = {2002}, abstract = {Structural design analyses are conducted with the aim of verifying the exclusion of ratcheting. To this end it is important to make a clear distinction between the shakedown range and the ratcheting range. In cyclic plasticity more sophisticated hardening models have been suggested in order to model the strain evolution observed in ratcheting experiments. The hardening models used in shakedown analysis are comparatively simple. It is shown that shakedown analysis can make quite stable predictions of admissible load ranges despite the simplicity of the underlying hardening models. A linear and a nonlinear kinematic hardening model of two-surface plasticity are compared in material shakedown analysis. Both give identical or similar shakedown ranges. Structural shakedown analyses show that the loading may have a more pronounced effect than the hardening model.}, subject = {Biomedizinische Technik}, language = {en} } @inproceedings{ArtmannStadlerEmbsetal.2010, author = {Artmann, Gerhard and Stadler, Andreas M. and Embs, Jan P. and Zaccai, Giuseppe and B{\"u}ldt, Georg and Digel, Ilya and Temiz Artmann, Ayseg{\"u}l}, title = {The crucial role of water in a phase transition of hemoglobin at body temperature : [abstract]}, year = {2010}, abstract = {The observation of a temperature transition of hemoglobin occurring at a critical temperature close to body temperature}, subject = {H{\"a}moglobin}, language = {en} } @inproceedings{StadlerEmbsZerlinetal.2007, author = {Stadler, Andreas M. and Embs, Jan P. and Zerlin, Kay and Digel, Ilya and Artmann, Gerhard and Zaccai, Joe and B{\"u}ldt, Georg}, title = {Temperature transitions of hemoglobin and cytosolic water diffusion in human red blood cells : [poster]}, year = {2007}, abstract = {Background Hemoglobin interactions in red blood cells Hemoglobin dynamics in human red blood cells Diffusion of H2O in red blood cells}, subject = {Erythrozyt}, language = {en} } @misc{Staat2006, author = {Staat, Manfred}, title = {Technische Mechanik. Vorlesungsmitschrift. Korrigierter Nachdr. der 3. Aufl.}, year = {2006}, abstract = {{\"U}berarbeitete, korrigierte und erg{\"a}nzte Version einer Vorlesungsmitschrift von Sebastian Kr{\"a}mer. 172 S. Inhaltsverzeichnis 0 Einf{\"u}hrung in die Mechanik 1 Statik starrer K{\"o}rper 2 Elastostatik (Festigkeitslehre) 3 Kinematik 4 Kinetik Literatur}, subject = {Technische Mechanik}, language = {de} } @inproceedings{KreyerStollenwerkSchoening2013, author = {Kreyer, J{\"o}rg and Stollenwerk, Dominik and Sch{\"o}ning, Michael Josef}, title = {Tagung des Forschernachwuchses der FH Aachen 20. November 2013 / ed.: J. Kreyer, D. Stollenwerk, M. J. Sch{\"o}ning}, publisher = {FH Aachen}, address = {Aachen}, pages = {64 S.}, year = {2013}, language = {de} }