@article{RossiHoltschoppenButenweg2019, author = {Rossi, Leonardo and Holtschoppen, Britta and Butenweg, Christoph}, title = {Official data on the economic consequences of the 2012 Emilia-Romagna earthquake: a first analysis of database SFINGE}, series = {Bulletin of Earthquake Engineering}, volume = {17}, journal = {Bulletin of Earthquake Engineering}, number = {9}, publisher = {Springer}, address = {Berlin}, doi = {10.1007\%2Fs10518-019-00655-8}, pages = {4855 -- 4884}, year = {2019}, language = {en} } @article{RossiStupazziniParisietal.2019, author = {Rossi, Leonardo and Stupazzini, Marco and Parisi, Davide and Holtschoppen, Britta and Ruggieri, Gabriella and Butenweg, Christoph}, title = {Empirical fragility functions and loss curves for long-span-beam buildings based on the 2012 Emilia-Romagna earthquake official database}, series = {Bulletin of Earthquake Engineering}, volume = {18}, journal = {Bulletin of Earthquake Engineering}, publisher = {Springer Nature}, issn = {1573-1456}, doi = {10.1007/s10518-019-00759-1}, pages = {1693 -- 1721}, year = {2019}, abstract = {The 2012 Emilia-Romagna earthquake, that mainly struck the homonymous Italian region provoking 28 casualties and damage to thousands of structures and infrastructures, is an exceptional source of information to question, investigate, and challenge the validity of seismic fragility functions and loss curves from an empirical standpoint. Among the most recent seismic events taking place in Europe, that of Emilia-Romagna is quite likely one of the best documented, not only in terms of experienced damages, but also for what concerns occurred losses and necessary reconstruction costs. In fact, in order to manage the compensations in a fair way both to citizens and business owners, soon after the seismic sequence, the regional administrative authority started (1) collecting damage and consequence-related data, (2) evaluating information sources and (3) taking care of the cross-checking of various reports. A specific database—so-called Sistema Informativo Gestione Europa (SFINGE)—was devoted to damaged business activities. As a result, 7 years after the seismic events, scientists can rely on a one-of-a-kind, vast and consistent database, containing information about (among other things): (1) buildings' location and dimensions, (2) occurred structural damages, (3) experienced direct economic losses and (4) related reconstruction costs. The present work is focused on a specific data subset of SFINGE, whose elements are Long-Span-Beam buildings (mostly precast) deployed for business activities in industry, trade or agriculture. With the available set of data, empirical fragility functions, cost and loss ratio curves are elaborated, that may be included within existing Performance Based Earthquake Engineering assessment toolkits.}, language = {en} } @article{PoghossianJablonskiMolinnusetal.2020, author = {Poghossian, Arshak and Jablonski, Melanie and Molinnus, Denise and Wege, Christina and Sch{\"o}ning, Michael Josef}, title = {Field-Effect Sensors for Virus Detection: From Ebola to SARS-CoV-2 and Plant Viral Enhancers}, series = {Frontiers in Plant Science}, volume = {11}, journal = {Frontiers in Plant Science}, number = {Article 598103}, publisher = {Frontiers}, address = {Lausanne}, doi = {10.3389/fpls.2020.598103}, pages = {1 -- 14}, year = {2020}, abstract = {Coronavirus disease 2019 (COVID-19) is a novel human infectious disease provoked by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, no specific vaccines or drugs against COVID-19 are available. Therefore, early diagnosis and treatment are essential in order to slow the virus spread and to contain the disease outbreak. Hence, new diagnostic tests and devices for virus detection in clinical samples that are faster, more accurate and reliable, easier and cost-efficient than existing ones are needed. Due to the small sizes, fast response time, label-free operation without the need for expensive and time-consuming labeling steps, the possibility of real-time and multiplexed measurements, robustness and portability (point-of-care and on-site testing), biosensors based on semiconductor field-effect devices (FEDs) are one of the most attractive platforms for an electrical detection of charged biomolecules and bioparticles by their intrinsic charge. In this review, recent advances and key developments in the field of label-free detection of viruses (including plant viruses) with various types of FEDs are presented. In recent years, however, certain plant viruses have also attracted additional interest for biosensor layouts: Their repetitive protein subunits arranged at nanometric spacing can be employed for coupling functional molecules. If used as adapters on sensor chip surfaces, they allow an efficient immobilization of analyte-specific recognition and detector elements such as antibodies and enzymes at highest surface densities. The display on plant viral bionanoparticles may also lead to long-time stabilization of sensor molecules upon repeated uses and has the potential to increase sensor performance substantially, compared to conventional layouts. This has been demonstrated in different proof-of-concept biosensor devices. Therefore, richly available plant viral particles, non-pathogenic for animals or humans, might gain novel importance if applied in receptor layers of FEDs. These perspectives are explained and discussed with regard to future detection strategies for COVID-19 and related viral diseases.}, language = {en} } @article{GoettenHavermannBraunetal.2020, author = {G{\"o}tten, Falk and Havermann, Marc and Braun, Carsten and Marino, Matthew and Bil, Cees}, title = {Improved Form Factor for Drag Estimation of Fuselages with Various Cross Sections}, series = {Journal of Aircraft}, journal = {Journal of Aircraft}, publisher = {AIAA}, address = {Reston, Va.}, issn = {1533-3868}, doi = {10.2514/1.C036032}, pages = {1 -- 13}, year = {2020}, abstract = {The paper presents an aerodynamic investigation of 70 different streamlined bodies with fineness ratios ranging from 2 to 10. The bodies are chosen to idealize both unmanned and small manned aircraft fuselages and feature cross-sectional shapes that vary from circular to quadratic. The study focuses on friction and pressure drag in dependency of the individual body's fineness ratio and cross section. The drag forces are normalized with the respective body's wetted area to comply with an empirical drag estimation procedure. Although the friction drag coefficient then stays rather constant for all bodies, their pressure drag coefficients decrease with an increase in fineness ratio. Referring the pressure drag coefficient to the bodies' cross-sectional areas shows a distinct pressure drag minimum at a fineness ratio of about three. The pressure drag of bodies with a quadratic cross section is generally higher than for bodies of revolution. The results are used to derive an improved form factor that can be employed in a classic empirical drag estimation method. The improved formulation takes both the fineness ratio and cross-sectional shape into account. It shows superior accuracy in estimating streamlined body drag when compared with experimental data and other form factor formulations of the literature.}, language = {en} } @article{GossmannThomasHorvathetal.2020, author = {Gossmann, Matthias and Thomas, Ulrich and Horv{\´a}th, Andr{\´a}s and Dragicevic, Elena and Stoelzle-Feix, Sonja and Jung, Alexander and Raman, Aravind Hariharan and Staat, Manfred and Linder, Peter}, title = {A higher-throughput approach to investigate cardiac contractility in vitro under physiological mechanical conditions}, series = {Journal of Pharmacological and Toxicological Methods}, volume = {105}, journal = {Journal of Pharmacological and Toxicological Methods}, number = {Article 106843}, publisher = {Elsevier}, address = {New York, NY}, doi = {10.1016/j.vascn.2020.106843}, year = {2020}, language = {en} } @incollection{FateriGebhardt2020, author = {Fateri, Miranda and Gebhardt, Andreas}, title = {Introduction to Additive Manufacturing}, series = {3D Printing of Optical Components}, booktitle = {3D Printing of Optical Components}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-58960-8}, doi = {10.1007/978-3-030-58960-8_1}, pages = {1 -- 22}, year = {2020}, abstract = {Additive manufacturing (AM) works by creating objects layer by layer in a manner similar to a 2D printer with the "printed" layers stacked on top of each other. The layer-wise manufacturing nature of AM enables fabrication of freeform geometries which cannot be fabricated using conventional manufacturing methods as a one part. Depending on how each layer is created and bonded to the adjacent layers, different AM methods have been developed. In this chapter, the basic terms, common materials, and different methods of AM are described, and their potential applications are discussed.}, language = {en} } @incollection{BozakovSander2013, author = {Bozakov, Zdravko and Sander, Volker}, title = {OpenFlow: A Perspective for Building Versatile Networks}, series = {Network-Embedded Management and Applications}, booktitle = {Network-Embedded Management and Applications}, publisher = {Springer}, address = {New York, NY}, isbn = {978-1-4419-6769-5}, doi = {10.1007/978-1-4419-6769-5_11}, pages = {217 -- 245}, year = {2013}, language = {en} } @inproceedings{GoettenFingerBraunetal.2019, author = {G{\"o}tten, Falk and Finger, Felix and Braun, Carsten and Havermann, Marc and Bil, C. and Gomez, F.}, title = {Empirical Correlations for Geometry Build-Up of Fixed Wing Unmanned Air Vehicles}, series = {APISAT 2018: The Proceedings of the 2018 Asia-Pacific International Symposium on Aerospace Technology (APISAT 2018)}, booktitle = {APISAT 2018: The Proceedings of the 2018 Asia-Pacific International Symposium on Aerospace Technology (APISAT 2018)}, publisher = {Springer}, address = {Singapore}, isbn = {978-981-13-3305-7}, doi = {10.1007/978-981-13-3305-7_109}, pages = {1365 -- 1381}, year = {2019}, abstract = {The results of a statistical investigation of 42 fixed-wing, small to medium sized (20 kg-1000 kg) reconnaissance unmanned air vehicles (UAVs) are presented. Regression analyses are used to identify correlations of the most relevant geometry dimensions with the UAV's maximum take-off mass. The findings allow an empirical based geometry-build up for a complete unmanned aircraft by referring to its take-off mass only. This provides a bridge between very early design stages (initial sizing) and the later determination of shapes and dimensions. The correlations might be integrated into a UAV sizing environment and allow designers to implement more sophisticated drag and weight estimation methods in this process. Additional information on correlation factors for a rough drag estimation methodology indicate how this technique can significantly enhance the accuracy of early design iterations.}, language = {en} } @inproceedings{FingerGoettenBraunetal.2019, author = {Finger, Felix and G{\"o}tten, Falk and Braun, Carsten and Bil, C.}, title = {On Aircraft Design Under the Consideration of Hybrid-Electric Propulsion Systems}, series = {APISAT 2018: The Proceedings of the 2018 Asia-Pacific International Symposium on Aerospace Technology (APISAT 2018)}, booktitle = {APISAT 2018: The Proceedings of the 2018 Asia-Pacific International Symposium on Aerospace Technology (APISAT 2018)}, publisher = {Springer}, address = {Singapore}, isbn = {978-981-13-3305-7}, doi = {10.1007/978-981-13-3305-7_99}, pages = {1261 -- 1272}, year = {2019}, abstract = {A hybrid-electric propulsion system combines the advantages of fuel-based systems and battery powered systems and offers new design freedom. To take full advantage of this technology, aircraft designers must be aware of its key differences, compared to conventional, carbon-fuel based, propulsion systems. This paper gives an overview of the challenges and potential benefits associated with the design of aircraft that use hybrid-electric propulsion systems. It offers an introduction of the most popular hybrid-electric propulsion architectures and critically assess them against the conventional and fully electric propulsion configurations. The effects on operational aspects and design aspects are covered. Special consideration is given to the application of hybrid-electric propulsion technology to both unmanned and vertical take-off and landing aircraft. The authors conclude that electric propulsion technology has the potential to revolutionize aircraft design. However, new and innovative methods must be researched, to realize the full benefit of the technology.}, language = {en} } @article{ConzenAlbannaWeissetal.2018, author = {Conzen, Catharina and Albanna, Walid and Weiss, Miriam and K{\"u}rten, David and Vilser, Walthard and Kotliar, Konstantin and Z{\"a}ske, Charlotte and Clusmann, Hans and Schubert, Gerrit Alexander}, title = {Vasoconstriction and Impairment of Neurovascular Coupling after Subarachnoid Hemorrhage: a Descriptive Analysis of Retinal Changes}, series = {Translational Stroke Research}, journal = {Translational Stroke Research}, number = {9}, publisher = {Springer Nature}, address = {Cham}, issn = {1868-601X}, doi = {10.1007/s12975-017-0585-8}, pages = {284 -- 293}, year = {2018}, abstract = {Impaired cerebral autoregulation and neurovascular coupling (NVC) contribute to delayed cerebral ischemia after subarachnoid hemorrhage (SAH). Retinal vessel analysis (RVA) allows non-invasive assessment of vessel dimension and NVC hereby demonstrating a predictive value in the context of various neurovascular diseases. Using RVA as a translational approach, we aimed to assess the retinal vessels in patients with SAH. RVA was performed prospectively in 24 patients with acute SAH (group A: day 5-14), in 11 patients 3 months after ictus (group B: day 90 ± 35), and in 35 age-matched healthy controls (group C). Data was acquired using a Retinal Vessel Analyzer (Imedos Systems UG, Jena) for examination of retinal vessel dimension and NVC using flicker-light excitation. Diameter of retinal vessels—central retinal arteriolar and venular equivalent—was significantly reduced in the acute phase (p < 0.001) with gradual improvement in group B (p < 0.05). Arterial NVC of group A was significantly impaired with diminished dilatation (p < 0.001) and reduced area under the curve (p < 0.01) when compared to group C. Group B showed persistent prolonged latency of arterial dilation (p < 0.05). Venous NVC was significantly delayed after SAH compared to group C (A p < 0.001; B p < 0.05). To our knowledge, this is the first clinical study to document retinal vasoconstriction and impairment of NVC in patients with SAH. Using non-invasive RVA as a translational approach, characteristic patterns of compromise were detected for the arterial and venous compartment of the neurovascular unit in a time-dependent fashion. Recruitment will continue to facilitate a correlation analysis with clinical course and outcome.}, language = {en} }