@article{TakenagaBiselliSchnitzleretal.2014,
  author    = {Takenaga, Shoko and Biselli, Manfred and Schnitzler, Thomas and {\"O}hlschl{\"a}ger, Peter and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Toward multi-analyte bioarray sensors: LAPS-based on-chip determination of a Michaelis-Menten-like kinetics for cell culturing},
  series = {Physica status solidi A : Applications and materials science},
  volume    = {211},
  journal   = {Physica status solidi A : Applications and materials science},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X (E); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)},
  doi       = {10.1002/pssa.201330464},
  pages     = {1410 -- 1415},
  year      = {2014},
  abstract  = {The metabolic activity of Chinese hamster ovary (CHO) cells was observed using a light-addressable potentiometric sensor (LAPS). The dependency toward different glucose concentrations (17-200 mM) follows a Michaelis-Menten kinetics trajectory with Kₘ = 32.8 mM, and the obtained Kₘ value in this experiment was compared with that found in literature. In addition, the pH shift induced by glucose metabolism of tumor cells transfected with the HPV-16 genome (C3 cells) was successfully observed. These results indicate the possibility to determine the tumor cells metabolism with a LAPS-based measurement device.},
  language  = {en}
}
@article{WagnerDollSchoening2014,
  author    = {Wagner, Patrick and Doll, Theodor and Sch{\"o}ning, Michael Josef},
  title     = {Engineering of functional interfaces / Patrick Wagner ; Theodor Doll ; Michael J. Sch{\"o}ning (eds.)},
  series = {Physica status solidi (A) : Applications and materials science},
  volume    = {211},
  journal   = {Physica status solidi (A) : Applications and materials science},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X (E-Book); 1862-6319 (E-Book); 0031-8965 (Print); 1862-6300 (Print)},
  doi       = {10.1002/pssa.201470241},
  pages     = {1339 -- 1339},
  year      = {2014},
  language  = {en}
}
@inproceedings{WernerYoshinobuMiyamotoetal.2014,
  author    = {Werner, Frederik and Yoshinobu, T. and Miyamoto, K. and Sch{\"o}ning, Michael Josef and Wagner, Torsten},
  title     = {Semiconductor-based sensors for imaging of chemical processes},
  series = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)},
  booktitle = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)},
  publisher = {VDE-Verl.},
  address   = {D{\"u}sseldorf},
  organization    = {VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik},
  isbn      = {978-3-8007-3622-5},
  pages     = {1 -- 5},
  year      = {2014},
  language  = {en}
}
@inproceedings{WuBronderPoghossianetal.2014,
  author    = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {DNA-hybridization detection using light-addressable potentiometric sensor modified with gold layer},
  series = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)},
  booktitle = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)},
  publisher = {VDE-Verl.},
  address   = {D{\"u}sseldorf},
  organization    = {VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik},
  isbn      = {978-3-8007-3622-5},
  pages     = {1 -- 4},
  year      = {2014},
  language  = {en}
}
@article{WuBronderPoghossianetal.2014,
  author    = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Werner, Frederik and B{\"a}cker, Matthias and Sch{\"o}ning, Michael Josef},
  title     = {Label-free electrical detection of DNA with a multi-spot LAPS: First step towards light-addressable DNA chips},
  series = {Physica status solidi A : Applications and materials science},
  volume    = {211},
  journal   = {Physica status solidi A : Applications and materials science},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)},
  doi       = {10.1002/pssa.201330442},
  pages     = {1423 -- 1428},
  year      = {2014},
  abstract  = {A multi-spot (4 × 4 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al-p-Si-SiO2 structure has been applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. Single-stranded probe ssDNA molecules (20 bases) were covalently immobilized onto the silanized SiO2 gate surface. The unspecific adsorption of mismatch ssDNA on the MLAPS gate surface was blocked by bovine serum albumin molecules. To reduce the screening effect and to achieve a high sensor signal, the measurements were performed in a low ionic-strength solution. The photocurrent-voltage (I-V) curves were simultaneously recorded on all 16 spots after each surface functionalization step. Large shifts of I-V curves of 25 mV were registered after the DNA immobilization and hybridization event. In contrast, a small potential shift (∼5 mV) was observed in case of mismatch ssDNA, revealing good specificity of the sensor. The obtained results demonstrate the potential of the MLAPS as promising transducer platform for the multi-spot label-free electrical detection of DNA molecules by their intrinsic molecular charge.},
  language  = {en}
}