@book{AbrahamAhmadianBuettgenbachetal.2021, author = {Abraham, Michelle and Ahmadian, Natalia and B{\"u}ttgenbach, Thomas and Keller, Nadja and Paumer, Marc and Plum, Axel}, title = {Aachener Online-Schriften Wirtschaft und Recht. Band 1/2021}, editor = {Kroll-Ludwigs, Kathrin and Bassen-Metz, Yasmine and Bernecker, Andreas and Eggert, Mathias and Fritz, Thomas and H{\"o}hne, Tim and Tran, Duc Hung and Vogt, J{\"u}rgen}, publisher = {FH Aachen / Fachbereich Wirtschaftswissenschaften}, address = {Aachen}, publisher = {Fachhochschule Aachen}, pages = {370 Seiten}, year = {2021}, abstract = {Inhaltsverzeichnis 1. Whistleblowing - Chancen \& Risiken von Hinweisgebersystemen aus Arbeitnehmer- und Arbeitgebersicht - Michelle Abraham 3-70 2. Die Bedeutung und rechtliche Bewertung von Vesting-Klauseln bei der Venture-Capital Finanzierung einer Start-Up GmbH - Natalia Ahmadian 71-137 3. Bewertung der M{\"o}glichkeit zur Einf{\"u}hrung von Tarifvertr{\"a}gen im deutschen Berufsfußball - Thomas B{\"u}ttgenbach 138-190 4. Pflichten und Haftungsrisiken des GmbH-Gesch{\"a}ftsf{\"u}hrers bei Compliance-Verst{\"o}ßen - Naja Keller 191-234 5. Aktienr{\"u}ckk{\"a}ufe auf dem deutschen Markt nach der Finanzkrise 2008/2009 - Marc Paumer 235-287 6. Will Germany reach its 2030 climate goals in the transportation sector? - An investigation focusing on the new German Emission Trading System - Axel Plum 288-369}, language = {de} } @article{AdelsElbersDiehletal.2023, author = {Adels, Klaudia and Elbers, Gereon and Diehl, Bernd and Monakhova, Yulia}, title = {Multicomponent analysis of dietary supplements containing glucosamine and chondroitin: comparative low- and high-field NMR spectroscopic study}, series = {Analytical Sciences}, volume = {2023}, journal = {Analytical Sciences}, publisher = {Springer Verlag}, address = {Cham}, issn = {1348-2246 (Online)}, doi = {10.1007/s44211-023-00433-2}, pages = {13 Seiten}, year = {2023}, abstract = {With the prevalence of glucosamine- and chondroitin-containing dietary supplements for people with osteoarthritis in the marketplace, it is important to have an accurate and reproducible analytical method for the quantitation of these compounds in finished products. NMR spectroscopic method based both on low- (80 MHz) and high- (500-600 MHz) field NMR instrumentation was established, compared and validated for the determination of chondroitin sulfate and glucosamine in dietary supplements. The proposed method was applied for analysis of 20 different dietary supplements. In the majority of cases, quantification results obtained on the low-field NMR spectrometer are similar to those obtained with high-field 500-600 MHz NMR devices. Validation results in terms of accuracy, precision, reproducibility, limit of detection and recovery demonstrated that the developed method is fit for purpose for the marketed products. The NMR method was extended to the analysis of methylsulfonylmethane, adulterant maltodextrin, acetate and inorganic ions. Low-field NMR can be a quicker and cheaper alternative to more expensive high-field NMR measurements for quality control of the investigated dietary supplements. High-field NMR instrumentation can be more favorable for samples with complex composition due to better resolution, simultaneously giving the possibility of analysis of inorganic species such as potassium and chloride.}, language = {en} } @article{AdelsMonakhova2024, author = {Adels, Klaudia and Monakhova, Yulia}, title = {Low-field NMR spectroscopic study of e-cigarettes: Is determination of only nicotine and organic carrier solvents possible?}, series = {Microchemical Journal}, volume = {203}, journal = {Microchemical Journal}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1095-9149}, doi = {10.1016/j.microc.2024.110859}, pages = {9 Seiten}, year = {2024}, abstract = {Electronic cigarettes (e-cigarettes) have become popular worldwide with the market growing exponentially in some countries. The absence of product standards and safety regulations requires urgent development of analytical methodologies for the holistic control of the growing diversity of such products. An approach based on low-field nuclear magnetic resonance (LF-NMR) at 80 MHz is presented for the simultaneous determination of key parameters: carrier solvents (vegetable glycerine (VG), propylene glycol (PG) and water), total nicotine as well as free-base nicotine fraction. Moreover, qualitative and quantitative determination of fourteen weak organic acids deliberately added to enhance sensory characteristics of e-cigarettes was possible. In most cases these parameters can be rapidly and conveniently determined without using any sample manipulation such as dilution, extraction or derivatization steps. The method was applied for 37 authentic e-cigarettes samples. In particular, eight different organic acids with the content up to 56 mg/mL were detected. Due to its simplicity, the method can be used in routine regulatory control as well as to study release behaviour of nicotine and other e-cigarettes constituents in different products.}, language = {en} } @article{AkimbekovMansurovJandosovetal.2013, author = {Akimbekov, Nuraly S. and Mansurov, Zulkhair and Jandosov, J. and Digel, Ilya and Gossmann, Matthias and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Zhubanova, Azhar A.}, title = {Wound healing activity of carbonized rice husk}, publisher = {Trans Tech Publications, Switzerland}, address = {B{\"a}ch}, year = {2013}, abstract = {The carbonized rice husk (CRH) was evaluated for its wound healing activity in rats using excision models. In this study, the influences of CRH on wound healing in rat skin in vivo and cellular behavior of human dermal fibroblasts in vitro were investigated. The obtained results showed that the CRH treatment promoted wound epithelization in rats and exhibited moderate inhibition of cell proliferation in vitro. CRH with lanolin oil treated wounds were found to epithelize faster as compared to controls.}, subject = {Wundheilung}, language = {en} } @masterthesis{Alef2023, type = {Bachelor Thesis}, author = {Alef, Sabrina}, title = {Miela : digitale Wissensvermittlung f{\"u}r Vorschulkinder}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {141 Seiten}, year = {2023}, abstract = {Kinder sind bei der Suche nach Antworten auf ihre Fragen in unserer medialen Gesellschaft stark mit dem digitalen Raum konfrontiert. Diese Medien k{\"o}nnen bei einer nicht kindergerechten Benutzung wichtige Entwicklungsprozesse hindern. Im Gegensatz dazu geben diese aber auch die M{\"o}glichkeit, Kindern wichtige Denkgewohnheiten beizubringen und sie besser auf die Zukunft vorzubereiten. Ziel der Arbeit ist es, eine Verbindung zwischen der analogen und digitalen Welt herzustellen und ein vielf{\"a}ltiges Lernen zu erm{\"o}glichen. Die App „miela" schafft eine neue Ebene der Wissensvermittlung durch die Kombination von digitaler und analoger Welt. Das Userinterface ist altersentsprechend gestaltet und bietet unterschiedliche Themenfelder an, wobei die Wissensvermittlung und die Kreativit{\"a}t im Fokus stehen. Eine Zusammenarbeit mit der Toniebox als digitale Erweiterung kann weitere Themenfelder anbieten.}, language = {de} } @article{AlexyukBogoyavlenskiyAlexyuketal.2021, author = {Alexyuk, Madina and Bogoyavlenskiy, Andrey and Alexyuk, Pavel and Moldakhanov, Yergali and Berezin, Vladimir and Digel, Ilya}, title = {Epipelagic microbiome of the Small Aral Sea: Metagenomic structure and ecological diversity}, series = {MicrobiologyOpen}, volume = {10}, journal = {MicrobiologyOpen}, number = {1}, publisher = {Wiley}, address = {Weinheim}, issn = {2045-8827}, doi = {10.1002/mbo3.1142}, pages = {1 -- 10}, year = {2021}, abstract = {Microbial diversity studies regarding the aquatic communities that experienced or are experiencing environmental problems are essential for the comprehension of the remediation dynamics. In this pilot study, we present data on the phylogenetic and ecological structure of microorganisms from epipelagic water samples collected in the Small Aral Sea (SAS). The raw data were generated by massive parallel sequencing using the shotgun approach. As expected, most of the identified DNA sequences belonged to Terrabacteria and Actinobacteria (40\% and 37\% of the total reads, respectively). The occurrence of Deinococcus-Thermus, Armatimonadetes, Chloroflexi in the epipelagic SAS waters was less anticipated. Surprising was also the detection of sequences, which are characteristic for strict anaerobes—Ignavibacteria, hydrogen-oxidizing bacteria, and archaeal methanogenic species. We suppose that the observed very broad range of phylogenetic and ecological features displayed by the SAS reads demonstrates a more intensive mixing of water masses originating from diverse ecological niches of the Aral-Syr Darya River basin than presumed before.}, language = {en} } @article{AlnemerKotliarNeuhausetal.2023, author = {Alnemer, Momin Sami Mohammad and Kotliar, Konstantin and Neuhaus, Valentin and Pape, Hans-Christoph and Ciritsis, Bernhard D.}, title = {Cost-effectiveness analysis of surgical proximal femur fracture prevention in elderly: a Markov cohort simulation model}, series = {Cost Effectiveness and Resource Allocation}, journal = {Cost Effectiveness and Resource Allocation}, number = {21, Article number: 77}, publisher = {Springer Nature}, issn = {1478-7547}, doi = {10.1186/s12962-023-00482-4}, pages = {12 Seiten}, year = {2023}, abstract = {Background Hip fractures are a common and costly health problem, resulting in significant morbidity and mortality, as well as high costs for healthcare systems, especially for the elderly. Implementing surgical preventive strategies has the potential to improve the quality of life and reduce the burden on healthcare resources, particularly in the long term. However, there are currently limited guidelines for standardizing hip fracture prophylaxis practices. Methods This study used a cost-effectiveness analysis with a finite-state Markov model and cohort simulation to evaluate the primary and secondary surgical prevention of hip fractures in the elderly. Patients aged 60 to 90 years were simulated in two different models (A and B) to assess prevention at different levels. Model A assumed prophylaxis was performed during the fracture operation on the contralateral side, while Model B included individuals with high fracture risk factors. Costs were obtained from the Centers for Medicare \& Medicaid Services, and transition probabilities and health state utilities were derived from available literature. The baseline assumption was a 10\% reduction in fracture risk after prophylaxis. A sensitivity analysis was also conducted to assess the reliability and variability of the results. Results With a 10\% fracture risk reduction, model A costs between \$8,850 and \$46,940 per quality-adjusted life-year (\$/QALY). Additionally, it proved most cost-effective in the age range between 61 and 81 years. The sensitivity analysis established that a reduction of ≥ 2.8\% is needed for prophylaxis to be definitely cost-effective. The cost-effectiveness at the secondary prevention level was most sensitive to the cost of the contralateral side's prophylaxis, the patient's age, and fracture treatment cost. For high-risk patients with no fracture history, the cost-effectiveness of a preventive strategy depends on their risk profile. In the baseline analysis, the incremental cost-effectiveness ratio at the primary prevention level varied between \$11,000/QALY and \$74,000/QALY, which is below the defined willingness to pay threshold. Conclusion Due to the high cost of hip fracture treatment and its increased morbidity, surgical prophylaxis strategies have demonstrated that they can significantly relieve the healthcare system. Various key assumptions facilitated the modeling, allowing for adequate room for uncertainty. Further research is needed to evaluate health-state-associated risks.}, language = {en} } @misc{Alt2016, author = {Alt, Helmut}, title = {Energiewende zwischen Wunsch und Wirklichkeit : Von der Grundlastdeckung zur L{\"u}ckenlastdeckung}, pages = {42 Folien}, year = {2016}, abstract = {Folien des Vortrags. VDI-Bezirksverband Dresden, Arbeitskreis Energietechnik, am Montag, 05.09.2016}, language = {de} } @inproceedings{Andorfer2007, author = {Andorfer, Johann}, title = {Parallelisierung und verteiltes Rechnen - Chancen f{\"u}r die Langzeitsimulation}, year = {2007}, abstract = {Dipl.Ing. Johann Andorfer , Tandler.com GmbH, Buch a. Erlbach. Abstract zum 1. Aachener Softwaretag in der Wasserwirtschaft <1,2007, Aachen>. 2 S. (S. 136-137) Eine nachhaltige Sicherung der Funktionalit{\"a}t und der {\"o}kologischen Vertr{\"a}glichkeit eines mittleren bis großen Kanalnetzes erfordert eine umfassende und detaillierte Modellierung in Raum und Zeit. Um den in den Richtlinien geforderten statistischen Anforderungen gerecht zu werden und die j{\"a}hrlichen H{\"a}ufigkeiten, Mengen und Zeitr{\"a}ume der Belastungen erwartungstreu absch{\"a}tzen zu k{\"o}nnen, ist es zielf{\"u}hrend und notwendig, lange Zeitr{\"a}ume und die Gesamtheit der Einzugsgebiete m{\"o}glichst detailliert zu betrachten. Die hydraulische Funktionalit{\"a}t und Sicherheit soll meistens mit Hilfe zeitsymmetrischer (hydrodynamischer) Verfahren nur durch Betrachtung von Modellregen, allenfalls Regenserien, sichergestellt werden. F{\"u}r die Absch{\"a}tzung der j{\"a}hrlich zu erwartenden Emissionen in unsere nat{\"u}rlichen Gew{\"a}sser mit ihren Mengen, Frequenzen und Dauern werden normalerweise Langzeitsimulationen nat{\"u}rlicher Regenreihen {\"u}ber m{\"o}glichst große Zeitr{\"a}ume mit zeitasymmetrischen (hydrologischen) Verfahren durchgef{\"u}hrt. Die betrachteten Kanalnetze werden zumeist vereinfacht (Grobnetze), um die Rechenzeiten ertr{\"a}glicher zu gestalten. W{\"u}nschenswert w{\"a}re jedoch eine allen Anforderungen gerecht werdende wirklichkeitsnahe Modellierung des gesamten Kanalnetzes in all seinen Details, Vermaschungen und Wechselwirkungen (Feinnetz) und dessen zeitsymmetrische und damit verl{\"a}ssliche Simulation mit langj{\"a}hrigen Regenreihen. Bereits vor 15 Jahren wurde im Hause Tandler begonnen, die Berechnungssoftware durch Parallelisierung auf symmetrische Multiprozessortechnologien auszurichten. In neuerer Zeit h{\"a}lt diese Technik durch die Mehrkernprozessoren in normalen Notebooks und PCs Einzug in die Ingenieurb{\"u}ros und Abwasserbetriebe und sorgt schon f{\"u}r wesentliche Einsparungen an Rechenzeit. Doch erst durch die Kombination der Parallelisierung mit dem Prinzip des verteilten Rechnens (d.h. die Einbeziehung mehrerer PCs eines Netzwerkes in die Berechnung) erh{\"a}lt man die Chance ausreichend Rechenkapazit{\"a}t zur Verf{\"u}gung zu stellen, um nicht nur eine einzelne Langzeitsimulation eines Feinnetzes durchzuf{\"u}hren, sondern sogar mehrere Sanierungsalternativen zu {\"u}berpr{\"u}fen. Die zukunftsweisenden Arbeiten von Dipl. Math. R. Tandler auf diesem Gebiet sind Thema dieses Vortrags.}, subject = {Kanalisation}, language = {de} } @masterthesis{Aretz2021, type = {Bachelor Thesis}, author = {Aretz, Jannik}, title = {Venus und Mars}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {41 Seiten}, year = {2021}, abstract = {Venus und Mars - Mann und Frau. Ein bin{\"a}res System, welches heutzutage einer st{\"a}ndigen Hinterfragung ausgesetzt ist. Woraus entstand dieses System und wie manipulativ ist das Geschlecht wirklich? Die Pionierwerke der Gender Studies/Queer Studies zeigten auf, dass jeder Mensch sein Geschlecht durch das Imitieren von sozial-gesellschaftlich festgelegten Normen und Werten bildet. Drag-K{\"u}nstler*innen leben diesen Prozess in einer visuellen Form vor, indem sie Geschlechternormen aufgreifen und sie unabh{\"a}ngig vom biologischen Geschlecht der Darstellenden inszenieren, imitieren, parodieren und neu zusammensetzen. Jede Performance auf den Fotografien greift ebenfalls vorhandene Vorstellungen von Geschlecht auf und interpretiert sie neu: denn Drag kennt kein Original, genauso wenig wie das Geschlecht.}, language = {de} }