@incollection{YoshinobuKrauseMiyamotoetal.2018, author = {Yoshinobu, Tatsuo and Krause, Steffi and Miyamoto, Ko-ichiro and Werner, Frederik and Poghossian, Arshak and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {(Bio-)chemical Sensing and Imaging by LAPS and SPIM}, series = {Label-free biosensing: advanced materials, devices and applications}, booktitle = {Label-free biosensing: advanced materials, devices and applications}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-75219-8}, pages = {103 -- 132}, year = {2018}, abstract = {The light-addressable potentiometric sensor (LAPS) and scanning photo-induced impedance microscopy (SPIM) are two closely related methods to visualise the distributions of chemical species and impedance, respectively, at the interface between the sensing surface and the sample solution. They both have the same field-effect structure based on a semiconductor, which allows spatially resolved and label-free measurement of chemical species and impedance in the form of a photocurrent signal generated by a scanning light beam. In this article, the principles and various operation modes of LAPS and SPIM, functionalisation of the sensing surface for measuring various species, LAPS-based chemical imaging and high-resolution sensors based on silicon-on-sapphire substrates are described and discussed, focusing on their technical details and prospective applications.}, language = {en} } @article{BohrnMuchaWerneretal.2013, author = {Bohrn, Ulrich and Mucha, Andreas and Werner, Frederik and Trattner, Barbara and B{\"a}cker, Matthias and Krumbe, Christoph and Schienle, Meinrad and St{\"u}tz, Evamaria and Schmitt-Landsiedel, Doris and Fleischer, Maximilian and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {A critical comparison of cell-based sensor systems for the detection of Cr (VI) in aquatic environment}, series = {Sensors and actuators. B: Chemical}, volume = {Vol. 182}, journal = {Sensors and actuators. B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-3077 (E-Journal); 0925-4005 (Print)}, pages = {58 -- 65}, year = {2013}, language = {en} } @article{WagnerWernerMiyamotoetal.2009, author = {Wagner, Torsten and Werner, Frederik and Miyamoto, K. and Sch{\"o}ning, Michael Josef and Yoshinobu, T.}, title = {A high-density multi-point LAPS set-up using a VCSEL array and FPGA control}, series = {Procedia Chemistry. 1 (2009), H. 1}, journal = {Procedia Chemistry. 1 (2009), H. 1}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {1876-6196}, pages = {1483 -- 1486}, year = {2009}, language = {en} } @article{WagnerWernerMiyamotoetal.2011, author = {Wagner, Torsten and Werner, Frederik and Miyamoto, Ko-Ichiro and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {A high-density multi-point LAPS set-up using a VCSEL array and FPGA control}, series = {Sensors and Actuators B: Chemical. 154 (2011), H. 2}, journal = {Sensors and Actuators B: Chemical. 154 (2011), H. 2}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {1873-3077}, pages = {124 -- 128}, year = {2011}, language = {en} } @article{MiyamotoHayashiSakamotoetal.2017, author = {Miyamoto, Ko-ichiro and Hayashi, Kosuke and Sakamoto, Azuma and Werner, Frederik and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {A high-Q resonance-mode measurement of EIS capacitive sensor by elimination of series resistance}, series = {Sensor and Actuators B: Chemical}, volume = {248}, journal = {Sensor and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2017.03.002}, pages = {1006 -- 1010}, year = {2017}, abstract = {An EIS capacitive sensor is a semiconductor-based potentiometric sensor, which is sensitive to the ion concentration or pH value of the solution in contact with the sensing surface. To detect a small change in the ion concentration or pH, a small capacitance change must be detected. Recently, a resonance-mode measurement was proposed, in which an inductor was connected to the EIS capacitive sensor and the resonant frequency was correlated with the pH value. In this study, the Q factor of the resonant circuit was enhanced by canceling the internal resistance of the reference electrode and the internal resistance of the inductor coil with the help of a bypass capacitor and a negative impedance converter, respectively. 1\% variation of the signal in the developed system corresponded to a pH change of 3.93 mpH, which was about 1/12 of the conventional method, suggesting a better performance in detection of a small pH change.}, language = {en} } @inproceedings{WuPoghossianWerneretal.2013, author = {Wu, Chunsheng and Poghossian, Arshak and Werner, Frederik and Bronder, Thomas and B{\"a}cker, Matthias and Wang, Ping and Sch{\"o}ning, Michael Josef}, title = {An application of a scanning light-addressable potentiometric sensor for label-free DNA detection}, series = {11. Dresdner Sensor-Symposium : 9.-11.12.2013}, booktitle = {11. Dresdner Sensor-Symposium : 9.-11.12.2013}, organization = {Dresdner Sensor-Symposium <11, 2013>}, isbn = {978-3-9813484-5-3}, pages = {164 -- 168}, year = {2013}, language = {en} } @article{WernerGroebelSchuhmacheretal.2009, author = {Werner, Frederik and Groebel, Simone and Schuhmacher, K. and Spelthahn, Heiko and Wagner, Torsten and Selmer, Thorsten and Baumann, Marcus and Sch{\"o}ning, Michael Josef}, title = {Bestimmung der metabolischen Aktivit{\"a}t von Mikroorganismen w{\"a}hrend des Biogasbildungsprozesses}, series = {9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.]}, journal = {9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.]}, publisher = {TUDpress}, address = {Dresden}, isbn = {978-3-941298-44-6}, pages = {201 -- 204}, year = {2009}, language = {de} } @inproceedings{TakenagaWernerSawadaetal.2012, author = {Takenaga, Shoko and Werner, Frederik and Sawada, Kazuaki and Sch{\"o}ning, Michael Josef}, title = {Comparison of label-free ACh image sensors based on CCD and LAPS}, isbn = {978-3-9813484-2-2}, doi = {10.5162/IMCS2012/4.2.6}, pages = {356 -- 359}, year = {2012}, language = {en} } @article{WernerTakenagaTakietal.2013, author = {Werner, Frederik and Takenaga, Shoko and Taki, Hidenori and Sawada, Kazuaki and Sch{\"o}ning, Michael Josef}, title = {Comparison of label-free ACh-imaging sensors based on CCD and LAPS}, series = {Sensors and Actuators B: Chemical (2012)}, volume = {177}, journal = {Sensors and Actuators B: Chemical (2012)}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0925-4005}, pages = {745 -- 752}, year = {2013}, abstract = {Semiconductor-based chemical imaging sensors, like the light-addressable potentiometric sensor (LAPS) or the pH-imaging sensor based on a charge-coupled device (CCD), are becoming a powerful tool for label-free imaging of biological phenomena. We have proposed a polyion-based enzymatic membrane to develop an acetylcholine (ACh) imaging sensor for neural cell-activity observations. In this study, a CCD-type ACh-imaging sensor and a LAPS-type ACh-imaging sensor were fabricated and the prospect of both sensors was clarified by making a comparison of their basic characteristics.}, language = {en} } @inproceedings{TakenagaHerreraWerneretal.2013, author = {Takenaga, Shoko and Herrera, Cony F. and Werner, Frederik and Biselli, Manfred and Schnitzler, Thomas and Sch{\"o}ning, Michael Josef and {\"O}hlschl{\"a}ger, Peter and Wagner, Torsten}, title = {Detection of the metabolic activity of cells by differential measurements based on a single light-addressable potentiometric sensor chip}, series = {11. Dresdner Sensor-Symposium : 9.-11.12.2013}, booktitle = {11. Dresdner Sensor-Symposium : 9.-11.12.2013}, organization = {Dresdner Sensor-Symposium <11, 2013>}, isbn = {978-3-9813484-5-3}, pages = {63 -- 67}, year = {2013}, language = {en} }