@misc{JansenBehbahaniLaumenetal.2010, author = {Jansen, Sebastian and Behbahani, Mehdi and Laumen, Marco and Kaufmann, Tim and Hormes, Marcus and Schmitz-Rode, Thomas and Behr, Marek and Steinseifer, Ulrich}, title = {3D stereo-PIV validation for CFD-simulation of steady flow through the human aorta using rapid-prototyping techniques}, year = {2010}, language = {en} } @inproceedings{NguyenRaatschenStaat2010, author = {Nguyen, N.-H. and Raatschen, Hans-J{\"u}rgen and Staat, Manfred}, title = {A hyperelastic model of biological tissue materials in tubular organs}, year = {2010}, language = {en} } @article{GrottkeBraunschweigPhilippenetal.2010, author = {Grottke, O. and Braunschweig, T. and Philippen, B. and Gatzweiler, Karl-Heinz and Gronloh, N. and Staat, Manfred and Rossaint, R. and Tolba, R.}, title = {A new model for blunt liver injuries in the swine}, series = {European Surgical Research}, volume = {44}, journal = {European Surgical Research}, number = {2}, publisher = {Karger}, address = {Basel}, issn = {1421-9921}, doi = {10.1159/000265053}, pages = {65 -- 73}, year = {2010}, abstract = {Background: To elaborate the impact of new haemostatic agents we developed an instrument for the pressure-controlled induction of blunt liver injuries in a porcine animal model. Materials and Methods: A dilutional coagulopathy of 80\% of animal blood volume was induced in 9 anaesthetized pigs. Animals were randomly assigned to be injured with a force of 112 Newton (N) (n = 1), 224 ± 19 N (n = 4) or 355 ± 35 N (n = 4). The impact of injury was measured by blood loss, survival time and coagulation parameters. Liver histology was obtained to evaluate the degree of liver injury. Results: The profound haemodilution resulted in a significant alteration of all coagulation parameters. After inflicting the injury with 355 ± 35 N, both the survival time (30 ± 9 min; p = 0.006) and blood loss (68 ± 16 ml min-1, p = 0.002) were significantly different as compared to injuries with 224 ± 19 N (survival time: 76 ± 20 min, blood loss: 23 ± 4 ml min-1). In contrast, an injury with 112 N led to an insignificant blood loss of only 239 ml. Conclusion: We developed a pressure-controlled clamp that allows for the induction of blunt liver traumas with highly reproducible injuries with a positive correlation with blood loss and survival.}, language = {en} } @inproceedings{PhamVuTranetal.2010, author = {Pham, Phu Tinh and Vu, Khoi Duc and Tran, Thanh Ngoc and Staat, Manfred}, title = {A primal-dual algorithm for shakedown analysis of elastic-plastic bounded linearly kinematic hardening bodies}, year = {2010}, language = {en} } @article{KozhalakovaZhubanovaMansurovetal.2010, author = {Kozhalakova, A. A. and Zhubanova, Azhar A. and Mansurov, Z. A. and Digel, Ilya and Tazhibayeva, S. M. and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l}, title = {Adsorption of bacterial lipopolysaccharides on carbonized rice shell}, series = {Science of Central Asia}, journal = {Science of Central Asia}, pages = {50 -- 54}, year = {2010}, language = {en} } @article{KurzLinderTrzewiketal.2010, author = {Kurz, R. and Linder, Peter and Trzewik, J{\"u}rgen and R{\"u}ffer, M. and Artmann, Gerhard and Digel, Ilya and Rothermel, A. and Robitzki, A. and Temiz Artmann, Ayseg{\"u}l}, title = {Contractile tension and beating rates of self-exciting monolayers and 3D-tissue constructs of neonatal rat cardiomyocytes}, series = {Medical and Biological Engineering and Computing}, volume = {48}, journal = {Medical and Biological Engineering and Computing}, number = {1}, publisher = {Springer Nature}, address = {Cham}, issn = {1741-0444}, doi = {10.1007/s11517-009-0552-y}, pages = {59 -- 65}, year = {2010}, abstract = {The CellDrum technology (The term 'CellDrum technology' includes a couple of slightly different technological setups for measuring lateral mechanical tension in various types of cell monolayers or 3D-tissue constructs) was designed to quantify the contraction rate and mechanical tension of self-exciting cardiac myocytes. Cells were grown either within flexible, circular collagen gels or as monolayer on top of respective 1-mum thin silicone membranes. Membrane and cells were bulged outwards by air pressure. This biaxial strain distribution is rather similar the beating, blood-filled heart. The setup allowed presetting the mechanical residual stress level externally by adjusting the centre deflection, thus, mimicking hypertension in vitro. Tension was measured as oscillating differential pressure change between chamber and environment. A 0.5-mm thick collagen-cardiac myocyte tissue construct induced after 2 days of culturing (initial cell density 2 x 10(4) cells/ml), a mechanical tension of 1.62 +/- 0.17 microN/mm(2). Mechanical load is an important growth regulator in the developing heart, and the orientation and alignment of cardiomyocytes is stress sensitive. Therefore, it was necessary to develop the CellDrum technology with its biaxial stress-strain distribution and defined mechanical boundary conditions. Cells were exposed to strain in two directions, radially and circumferentially, which is similar to biaxial loading in real heart tissues. Thus, from a biomechanical point of view, the system is preferable to previous setups based on uniaxial stretching.}, language = {en} } @article{HeinzelSchaeferMuelleretal.2010, author = {Heinzel, Alexander and Sch{\"a}fer, Ralf and M{\"u}ller, Hans-Wilhelm and Schieffer, Andre and Ingenhag, Ariane and Northoff, Georg and Franz, Matthias and Hautzel, Hubertus}, title = {Differential modulation of valence and arousal in high-alexithymic and low-alexithymic individuals}, series = {Neuroreport}, volume = {21}, journal = {Neuroreport}, number = {15}, publisher = {Lippincott Williams \& Wilkins}, address = {London}, issn = {1473-558X}, doi = {10.1097/WNR.0b013e32833f38e0}, pages = {998 -- 1002}, year = {2010}, abstract = {High-alexithymic individuals are characterized by an impaired ability to identify and communicate emotions whereas low-alexithymic individuals have a wide-ranging ability to deal with emotions. This study examined the hypothesis that valence and arousal modifications of emotional stimuli differentially modulate cortical regions in high-alexithymic and low-alexithymic individuals. To this end, 28 high-alexithymic and 25 low-alexithymic individuals were investigated with event-related fMRI using visual emotional stimuli. We found differential neural activations in the dorsal anterior cingulate, the insula and the amygdala. We suggest that these differences may account for the impaired ability of high-alexithymic individuals to appropriately handle emotional stimuli.}, language = {en} } @article{LanzlSeidovaErbenetal.2010, author = {Lanzl, Ines M. and Seidova, Seid-Fatima and Erben, A. and Th{\"u}rmel, K. and Kotliar, Konstantin}, title = {Diffuse stromale Hornhauttr{\"u}bungen und Ver{\"a}nderungen der H{\"a}nde}, series = {Der Ophthalmologe}, volume = {107}, journal = {Der Ophthalmologe}, number = {4}, publisher = {Springer}, address = {Berlin}, issn = {1433-0423}, doi = {10.1007/s00347-009-2066-2}, pages = {363 -- 365}, year = {2010}, abstract = {Bilaterale stromale Hornhauttr{\"u}bungen sind f{\"u}r den Augenarzt eine differenzialdiagnostische Herausforderung. Im folgenden Beitrag werden 2 Patieninnen (30 und 36 Jahre) mit unterschiedlich stark ausgepr{\"a}gter stromaler diffuser Hornhauttr{\"u}bung vorgestellt. Patientin 1 war kleinw{\"u}chsig (114 cm) und Patientin 2 normal groß (172 cm). Beide Patientinnen wiesen ver{\"a}nderte Gelenkstrukturen an Hand und Fußgelenken sowie diffuse stromale Hornhauttr{\"u}bungen auf. Des Weiteren lagen eine Mitral- und Aorteninsuffizienz (Patientin 1) bzw. eine Aorteninsuffizienz (Patientin 2) vor. Die stromalen diffusen Hornhauttr{\"u}bungen ließen im Zusammenhang mit den Gelenkver{\"a}nderungen ein Scheie-Syndrom vermuten. Therapeutisch ist bei Patienten mit Visusminderung eine (lamell{\"a}re) Keratoplastik sinnvoll.}, language = {de} } @incollection{StaatSponagelNguyen2010, author = {Staat, Manfred and Sponagel, Stefan and Nguyen, Nhu Huynh}, title = {Experiment and material model for soft tissue materials}, series = {Constitutive models for rubber VI}, booktitle = {Constitutive models for rubber VI}, publisher = {Taylor \& Francis}, address = {London}, isbn = {9780429206597 (eBook)}, doi = {10.1201/NOE0415563277-90}, pages = {6 Seiten}, year = {2010}, abstract = {Biomechanics studies biological soft tissue materials (growth, remodeling) in vivo. For this objective, the detailed information of material properties must be well defined to construct reliable constitutive models. In the paper, the bulge test is carried out with elastomers in order to develop a test method. Then, application of the test for soft tissue materials is straightforward due to the similarities between elastomers with soft tissue materials as proved in Holzapfel 2005, Ogden 2009. It means, after the preliminary experiments and parameter identification with rubber materials has been setup, experiments on soft tissue materials can be similarly carried out. Elastomers have a complex behavior which strongly depends on the largest previous load cycle. For simplicity we consider only the first loading.}, language = {en} } @article{LeimenaArtmannDachwaldetal.2010, author = {Leimena, W. and Artmann, Gerhard and Dachwald, Bernd and Temiz Artmann, Ayseg{\"u}l and Gossmann, Matthias and Digel, Ilya}, title = {Feasibility of an in-situ microbial decontamination of an ice-melting probe}, series = {Eurasian Chemico-Technological Journal}, volume = {12}, journal = {Eurasian Chemico-Technological Journal}, number = {2}, publisher = {Institute of Combustion Problems}, address = {Almaty}, isbn = {1562-3920}, doi = {10.18321/ectj37}, pages = {145 -- 150}, year = {2010}, abstract = {Autonomous robotic systems for penetrating thick ice shells with simultaneous collecting of scientific data are very promising devices in both terrestrial (glacier, climate research) and extra-terrestrial applications. Technical challenges in development of such systems are numerous and include 3D-navigation, an appropriate energy source, motion control, etc. Not less important is the problem of forward contamination of the pristine glacial environments with microorganisms and biomolecules from the surface of the probe. This study was devoted to establishing a laboratory model for microbial contamination of a newly constructed ice-melting probe called IceMole and to analyse the viability and amount of the contaminating microorganisms as a function of distance. The used bacterial strains were Bacillus subtilis (ATCC 6051) and Escherichia coli (ATCC 11775). The main objective was development of an efficient and reliable in-situ decontamination method of the melting probe. Therefore, several chemical substances were tested in respect of their efficacy to eliminate bacteria on the surface of the melting probe at low temperature (0 - 5 °C) and at continuous dilution by melted water. Our study has shown that at least 99.9\% decontamination of the IceMole can be successfully achieved by the injection of 30\% (v/v) hydrogen peroxide and 3\% (v/v) sodium hypochlorite into the drilling site. We were able to reproduce this result in both time-dependent and depth-dependent experiments. The sufficient amount of 30\% (v/v) H₂O₂ or 3\% (v/v) NaClO has been found to be approximately 18 L per cm² of the probe's surface.}, language = {en} }