@article{Golland2018,
  author    = {Golland, Alexander},
  title     = {Das neue kirchliche Datenschutzrecht - Herausforderungen f{\"u}r Unternehmen der Privatwirtschaft},
  series = {DSB Datenschutz-Berater},
  volume    = {42},
  journal   = {DSB Datenschutz-Berater},
  number    = {9},
  publisher = {dfv Mediengruppe},
  address   = {Frankfurt a.M.},
  isbn      = {0170-7256},
  pages     = {179 -- 181},
  year      = {2018},
  language  = {de}
}
@article{Olbertz2018,
  author    = {Olbertz, Klaus},
  title     = {Das rechtssichere Arbeitszeugnis - Erlaubte und nicht erlaubte Formulierungen und anderes Wissenswertes},
  series = {NWB - Steuer- und Wirtschaftsrecht},
  journal   = {NWB - Steuer- und Wirtschaftsrecht},
  number    = {12},
  publisher = {NWB-Verl.},
  address   = {Herne},
  issn      = {1860-9449},
  pages     = {802 -- 813},
  year      = {2018},
  language  = {de}
}
@article{Olbertz2018,
  author    = {Olbertz, Klaus},
  title     = {Der Interimsmanager als Selbst{\"a}ndiger oder Arbeitnehmer : Vertragliche Varianten des Interimsmanagements im Faktencheck},
  series = {NWB - Steuer- und Wirtschaftsrecht},
  journal   = {NWB - Steuer- und Wirtschaftsrecht},
  number    = {31},
  publisher = {NWB-Verl.},
  address   = {Herne},
  issn      = {1860-9449},
  pages     = {2260 -- 2266},
  year      = {2018},
  language  = {de}
}
@article{Golland2018,
  author    = {Golland, Alexander},
  title     = {Der r{\"a}umliche Anwendungsbereich der DS-GVO},
  series = {DuD Datenschutz und Datensicherheit},
  volume    = {42},
  journal   = {DuD Datenschutz und Datensicherheit},
  number    = {6},
  publisher = {Springer},
  address   = {Heidelberg},
  isbn      = {1862-2607},
  pages     = {351 -- 357},
  year      = {2018},
  abstract  = {Die Datenschutz-Grundverordnung (DS-GVO) regelt in ihrem Art. 3 das r{\"a}umlich anwendbare Datenschutzrecht und zielt dabei gerade auch auf Angebote nichteurop{\"a}ischer Diensteanbieter ab. Die bisherige Diskussion konzentriert sich bislang in erster Linie darauf, das eingef{\"u}hrte Marktortprinzip zu thematisieren; das weitgehend unangetastete Niederlassungsprinzip und vor allem die Probleme, die sich durch dessen unver{\"a}nderte Beibehaltung ergeben, werden dagegen nicht er{\"o}rtert. Der folgende Beitrag versucht sich an einer systematischen Analyse eines teils kontrovers, teils kaum diskutierten Themas.},
  language  = {de}
}
@article{FissabreWilson2018,
  author    = {Fissabre, Anke and Wilson, Ariane},
  title     = {Der Turm mit zehn Spornen - Ein in Monthoiron gebauter Entwurf von Leonardo Da Vinci?},
  series = {In situ: Zeitschrift f{\"u}r Architekturgeschichte},
  journal   = {In situ: Zeitschrift f{\"u}r Architekturgeschichte},
  number    = {1},
  publisher = {Wernersche Verlagsgesellschaft},
  address   = {Worms},
  issn      = {1866-959X},
  pages     = {65 -- 82},
  year      = {2018},
  language  = {de}
}
@book{Kurz2018,
  author    = {Kurz, Melanie},
  title     = {Designstreit : exemplarische Kontroversen {\"u}ber Gestaltung},
  publisher = {Wilhelm Fink},
  address   = {Paderborn},
  isbn      = {978-3-7705-6294-7 (Druckausgabe)},
  pages     = {304 Seiten},
  year      = {2018},
  abstract  = {Die Geschichte des Designs ist ges{\"a}umt von Auseinandersetzungen. Debattiert wird unter Berufsgenossen, in Interessensverb{\"a}nden, zwischen Wettbewerbern und nicht zuletzt an Hochschulen; als Foren dienen zum Beispiel Zeitungen, Konferenzen oder Gerichtss{\"a}le. Doch welche Gr{\"u}nde gibt es f{\"u}r Streit {\"u}ber Design? Die Kontroversen beschr{\"a}nken sich keineswegs auf die {\"A}sthetik von Artefakten. Auch haben wir es trotz der Vielfalt an Streitf{\"a}llen nicht mit einem un{\"u}berschaubaren Feld von zusammenhanglosen Einzelereignissen zu tun. Wie das vorliegende Buch anhand historischer Kontroversen zeigt, lassen sich im Bereich der Gestaltung Streitkategorien identifizieren. Die Diskursanalyse verr{\"a}t, dass sich die Konfliktursachen im Verlauf der Designhistorie kaum ver{\"a}ndern. So haben die angef{\"u}hrten Dispute erstaunliche {\"A}hnlichkeit mit aktuellen Debatten im Fach. Sie sind Lehrst{\"u}cke und k{\"o}nnen dazu anregen, eine Streitkultur im Design zu etablieren, die sich davon distanziert, den Meinungsgegner in ein politisches Lager zu ›verr{\"a}umen‹.},
  language  = {de}
}
@article{MolinnusHardtSiegertetal.2018,
  author    = {Molinnus, Denise and Hardt, Gabriel and Siegert, Petra and Willenberg, Holger S. and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Detection of Adrenaline in Blood Plasma as Biomarker for Adrenal Venous Sampling},
  series = {Electroanalysis},
  volume    = {30},
  journal   = {Electroanalysis},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-4109},
  doi       = {10.1002/elan.201800026},
  pages     = {937 -- 942},
  year      = {2018},
  abstract  = {An amperometric bi-enzyme biosensor based on substrate recycling principle for the amplification of the sensor signal has been developed for the detection of adrenaline in blood. Adrenaline can be used as biomarker verifying successful adrenal venous sampling procedure. The adrenaline biosensor has been realized via modification of a galvanic oxygen sensor with a bi-enzyme membrane combining a genetically modified laccase and a pyrroloquinoline quinone-dependent glucose dehydrogenase. The measurement conditions such as pH value and temperature were optimized to enhance the sensor performance. A high sensitivity and a low detection limit of about 0.5-1 nM adrenaline have been achieved in phosphate buffer at pH 7.4, relevant for measurements in blood samples. The sensitivity of the biosensor to other catecholamines such as noradrenaline, dopamine and dobutamine has been studied. Finally, the sensor has been successfully applied for the detection of adrenaline in human blood plasma.},
  language  = {en}
}
@article{BronderJessingPoghossianetal.2018,
  author    = {Bronder, Thomas and Jessing, Max P. and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Detection of PCR-Amplified Tuberculosis DNA Fragments with Polyelectrolyte-Modified Field-Effect Sensors},
  series = {Analytical Chemistry},
  volume    = {90},
  journal   = {Analytical Chemistry},
  number    = {12},
  publisher = {ACS Publications},
  address   = {Washington, DC},
  issn      = {0003-2700},
  doi       = {10.1021/acs.analchem.8b01807},
  pages     = {7747 -- 7753},
  year      = {2018},
  abstract  = {Field-effect-based electrolyte-insulator-semiconductor (EIS) sensors were modified with a bilayer of positively charged weak polyelectrolyte (poly(allylamine hydrochloride) (PAH)) and probe single-stranded DNA (ssDNA) and are used for the detection of complementary single-stranded target DNA (cDNA) in different test solutions. The sensing mechanism is based on the detection of the intrinsic molecular charge of target cDNA molecules after the hybridization event between cDNA and immobilized probe ssDNA. The test solutions contain synthetic cDNA oligonucleotides (with a sequence of tuberculosis mycobacteria genome) or PCR-amplified DNA (which origins from a template DNA strand that has been extracted from Mycobacterium avium paratuberculosis-spiked human sputum samples), respectively. Sensor responses up to 41 mV have been measured for the test solutions with DNA, while only small signals of ∼5 mV were detected for solutions without DNA. The lower detection limit of the EIS sensors was ∼0.3 nM, and the sensitivity was ∼7.2 mV/decade. Fluorescence experiments using SybrGreen I fluorescence dye support the electrochemical results.},
  language  = {en}
}
@article{MolinnusMuschallikGonzalezetal.2018,
  author    = {Molinnus, Denise and Muschallik, Lukas and Gonzalez, Laura Osorio and Bongaerts, Johannes and Wagner, Torsten and Selmer, Thorsten and Siegert, Petra and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Development and characterization of a field-effect biosensor for the detection of acetoin},
  series = {Biosensors and Bioelectronics},
  volume    = {115},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.bios.2018.05.023},
  pages     = {1 -- 6},
  year      = {2018},
  abstract  = {A capacitive electrolyte-insulator-semiconductor (EIS) field-effect biosensor for acetoin detection has been presented for the first time. The EIS sensor consists of a layer structure of Al/p-Si/SiO₂/Ta₂O₅/enzyme acetoin reductase. The enzyme, also referred to as butane-2,3-diol dehydrogenase from B. clausii DSM 8716T, has been recently characterized. The enzyme catalyzes the (R)-specific reduction of racemic acetoin to (R,R)- and meso-butane-2,3-diol, respectively. Two different enzyme immobilization strategies (cross-linking by using glutaraldehyde and adsorption) have been studied. Typical biosensor parameters such as optimal pH working range, sensitivity, hysteresis, linear concentration range and long-term stability have been examined by means of constant-capacitance (ConCap) mode measurements. Furthermore, preliminary experiments have been successfully carried out for the detection of acetoin in diluted white wine samples.},
  language  = {en}
}
@article{AboulnagaZouSelmeretal.2018,
  author    = {Aboulnaga, E. A. and Zou, H. and Selmer, Thorsten and Xian, M.},
  title     = {Development of a plasmid-based, tunable, tolC-derived expression system for application in Cupriavidus necator H16},
  series = {Journal of Biotechnology},
  volume    = {274},
  journal   = {Journal of Biotechnology},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0168-1656},
  doi       = {10.1016/j.jbiotec.2018.03.007},
  pages     = {15 -- 27},
  year      = {2018},
  abstract  = {Cupriavidus necator H16 gains increasing attention in microbial research and biotechnological application due to its diverse metabolic features. Here we present a tightly controlled gene expression system for C. necator including the pBBR1-vector that contains hybrid promoters originating from C. necator native tolC-promoter in combination with a synthetic tetO-operator. The expression of the reporter gene from these plasmids relies on the addition of the exogenous inducer doxycycline (dc). The novel expression system offers a combination of advantageous features as; (i) high and dose-dependent recombinant protein production, (ii) tight control with a high dynamic range (On/Off ratio), which makes it applicable for harmful pathways or for toxic protein production, (iii) comparable cheap inducer (doxycycline, dc), (iv) effective at low inducer concentration, that makes it useful for large scale application, (v) rapid, diffusion controlled induction, and (vi) the inducer does not interfere within the cell metabolism. As applications of the expression system in C. necator H16, the growth ability on glycerol was enhanced by constitutively expressing the E. coli glpk gene-encoding for glycerol kinase. Likewise, we used the system to overcome the expression toxicity of mevalonate pathway in C. necator H16. With this system, the mevalonate-genes were successfully introduced in the host and the recombinant strains could produce about 200 mg/l mevalonate.},
  language  = {en}
}