@article{FalkenbergVossBottetal.2023, author = {Falkenberg, Fabian and Voß, Leonie and Bott, Michael and Bongaerts, Johannes and Siegert, Petra}, title = {New robust subtilisins from halotolerant and halophilic Bacillaceae}, series = {Applied Microbiology and Biotechnology}, volume = {107}, journal = {Applied Microbiology and Biotechnology}, publisher = {Springer Nature}, address = {Berlin}, issn = {1432-0614}, doi = {10.1007/s00253-023-12553-w}, pages = {3939 -- 3954}, year = {2023}, abstract = {The aim of the present study was the characterisation of three true subtilisins and one phylogenetically intermediate subtilisin from halotolerant and halophilic microorganisms. Considering the currently growing enzyme market for efficient and novel biocatalysts, data mining is a promising source for novel, as yet uncharacterised enzymes, especially from halophilic or halotolerant Bacillaceae, which offer great potential to meet industrial needs. Both halophilic bacteria Pontibacillus marinus DSM 16465ᵀ and Alkalibacillus haloalkaliphilus DSM 5271ᵀ and both halotolerant bacteria Metabacillus indicus DSM 16189 and Litchfieldia alkalitelluris DSM 16976ᵀ served as a source for the four new subtilisins SPPM, SPAH, SPMI and SPLA. The protease genes were cloned and expressed in Bacillus subtilis DB104. Purification to apparent homogeneity was achieved by ethanol precipitation, desalting and ion-exchange chromatography. Enzyme activity could be observed between pH 5.0-12.0 with an optimum for SPPM, SPMI and SPLA around pH 9.0 and for SPAH at pH 10.0. The optimal temperature for SPMI and SPLA was 70 °C and for SPPM and SPAH 55 °C and 50 °C, respectively. All proteases showed high stability towards 5\% (w/v) SDS and were active even at NaCl concentrations of 5 M. The four proteases demonstrate potential for future biotechnological applications.}, language = {en} } @article{LuftBremenLuft2023, author = {Luft, Angela and Bremen, Sebastian and Luft, Nils}, title = {A cost/benefit and flexibility evaluation framework for additive technologies in strategic factory planning}, series = {Processes}, volume = {11}, journal = {Processes}, number = {7}, publisher = {MDPI}, address = {Basel}, issn = {2227-9717}, doi = {10.3390/pr11071968}, pages = {Artikel 1968}, year = {2023}, abstract = {There is a growing demand for more flexibility in manufacturing to counter the volatility and unpredictability of the markets and provide more individualization for customers. However, the design and implementation of flexibility within manufacturing systems are costly and only economically viable if applicable to actual demand fluctuations. To this end, companies are considering additive manufacturing (AM) to make production more flexible. This paper develops a conceptual model for the impact quantification of AM on volume and mix flexibility within production systems in the early stages of the factory-planning process. Together with the model, an application guideline is presented to help planners with the flexibility quantification and the factory design process. Following the development of the model and guideline, a case study is presented to indicate the potential impact additive technologies can have on manufacturing flexibility Within the case study, various scenarios with different production system configurations and production programs are analyzed, and the impact of the additive technologies on volume and mix flexibility is calculated. This work will allow factory planners to determine the potential impacts of AM on manufacturing flexibility in an early planning stage and design their production systems accordingly.}, language = {en} } @masterthesis{Kappel2023, type = {Bachelor Thesis}, author = {Kappel, Jana Naomi}, title = {KLIKK : ein smartes Kinderprodukt f{\"u}r den altersgerechten Einstieg in die digitale Welt}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {163 Seiten}, year = {2023}, abstract = {Die neue Generation wird mit einer Medienwelt konfrontiert, welche nicht auf unsere kleinen Nutzer:innen ausgelegt ist. Die Verwendung von digitalen Medien hatte nie einen gr{\"o}ßeren Einfluss auf unsere Gesellschaft wie im Hier und Jetzt. Somit ist es von großer Relevanz, diese Nutzung kindergerechter zu gestalten und einen sicheren Rahmen f{\"u}r sie zu schaffen. Das Bachelorprojekt „KLIKK" legt einen L{\"o}sungsentwurf f{\"u}r den altersgerechten Einstieg f{\"u}r Kinder in diese digitale Welt vor, um den richtigen Umgang mit Smartwatches und darauf aufbauende Medien zu erm{\"o}glichen und gleichzeitig einen p{\"a}dagogischen Mehrwert zu bieten. Das didaktische Produktkonzept, welches explizit f{\"u}r Kinder designed wurde, beinhaltet das Erlernen des Uhrlesens und befriedigt das aufkommende Bed{\"u}rfnis nach Vernetzung in einem sicheren System. Zudem f{\"o}rdert es die Autonomie und ist an die kindliche Motorik angepasst. Mitinitiator und Namensgeber f{\"u}r diese Konzeption ist die deutsche Kinderuhrenmarke KWIO. KLIKK inkludiert Sicherheit, die Freude am Lernen und bietet eine M{\"o}glichkeit, die Kleinen ganz groß in unsere digitale Welt aufzunehmen.}, language = {de} } @article{MaurerRiekeSchemmetal.2023, author = {Maurer, Florian and Rieke, Christian and Schemm, Ralf and Stollenwerk, Dominik}, title = {Analysis of an urban grid with high photovoltaic and e-mobility penetration}, series = {Energies}, volume = {16}, journal = {Energies}, number = {8}, publisher = {MDPI}, address = {Basel}, issn = {1996-1073}, doi = {10.3390/en16083380}, pages = {18 Seiten}, year = {2023}, abstract = {This study analyses the expected utilization of an urban distribution grid under high penetration of photovoltaic and e-mobility with charging infrastructure on a residential level. The grid utilization and the corresponding power flow are evaluated, while varying the control strategies and photovoltaic installed capacity in different scenarios. Four scenarios are used to analyze the impact of e-mobility. The individual mobility demand is modelled based on the largest German studies on mobility "Mobilit{\"a}t in Deutschland", which is carried out every 5 years. To estimate the ramp-up of photovoltaic generation, a potential analysis of the roof surfaces in the supply area is carried out via an evaluation of an open solar potential study. The photovoltaic feed-in time series is derived individually for each installed system in a resolution of 15 min. The residential consumption is estimated using historical smart meter data, which are collected in London between 2012 and 2014. For a realistic charging demand, each residential household decides daily on the state of charge if their vehicle requires to be charged. The resulting charging time series depends on the underlying behavior scenario. Market prices and mobility demand are therefore used as scenario input parameters for a utility function based on the current state of charge to model individual behavior. The aggregated electricity demand is the starting point of the power flow calculation. The evaluation is carried out for an urban region with approximately 3100 residents. The analysis shows that increased penetration of photovoltaics combined with a flexible and adaptive charging strategy can maximize PV usage and reduce the need for congestion-related intervention by the grid operator by reducing the amount of kWh charged from the grid by 30\% which reduces the average price of a charged kWh by 35\% to 14 ct/kWh from 21.8 ct/kWh without PV optimization. The resulting grid congestions are managed by implementing an intelligent price or control signal. The analysis took place using data from a real German grid with 10 subgrids. The entire software can be adapted for the analysis of different distribution grids and is publicly available as an open-source software library on GitHub.}, language = {en} } @masterthesis{Katemann2023, type = {Bachelor Thesis}, author = {Katemann, Ronja Mairin}, title = {Gaming for everyone : gender-inklusives Gaming Equipment}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {139 Seiten}, year = {2023}, abstract = {Das Ausleben von Sexualit{\"a}t und Gender befindet sich im gesellschaftlichen Wandel. Vor allem junge Menschen lassen ihre Lebenswege nicht mehr von traditionellen Geschlechterrollen und -normen leiten. In einigen Bereichen ist das schon deutlich sichtbar, w{\"a}hrend andere Bereiche noch vor Herausforderungen stehen, wenn es um Inklusion, Akzeptanz und Repr{\"a}sentation geht. Besonders betroffen ist dabei der Gamingbereich, der repr{\"a}sentativ nach wie vor ein m{\"a}nnlich-dominiertes Gebiet zu sein scheint und durch Vorurteile gegen{\"u}ber Frauen und der LGBTQIA+ Community stigmatisiert ist. Die _FLUX Gaming Maus soll durch Gender-inklusives Design dazu beitragen, stereotype Rollenbilder in der Gaming Welt aufzubrechen und die Community nachhaltig wachsen zu lassen. Sie bietet dabei eine Alternative zu den „typisch m{\"a}nnlich" wirkenden Gaming Produkten auf dem Markt. Durch verschiedene Individualisierungsm{\"o}glichkeiten in Funktion und Gestalt kann _FLUX in einem Online-Konfigurator an den pers{\"o}nlichen Spielstil angepasst werden. So vermittelt _FLUX Zugeh{\"o}rigkeit und Repr{\"a}sentation unabh{\"a}ngig von Geschlecht und bietet Spaß am Gaming f{\"u}r jede:n.}, language = {de} } @masterthesis{Kilcher2023, type = {Bachelor Thesis}, author = {Kilcher, Mathias}, title = {Barrierefreies Klettern : ein System zur Inklusion sehbehinderter Menschen in den Klettersport}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {135 Seiten}, year = {2023}, abstract = {Ziel des Projekts war die Entwicklung eines Systems, das es Menschen mit starker Sehbehinderung erm{\"o}glicht, Klettersport als ein Training f{\"u}r ihren K{\"o}rper und ihren Orientierungssinn nutzen zu k{\"o}nnen. Inklusion ist als gesellschaftliches Thema in den letzten Jahren stark in den Fokus ger{\"u}ckt. Dennoch ist es f{\"u}r Menschen mit Behinderung oft schwer, sozialen Anschluss zu finden. Dies wird zus{\"a}tzlich durch das mangelnde Angebot an inklusiven Freizeitaktivit{\"a}ten erschwert. Apollon erm{\"o}glicht Menschen mit starker Sehbehinderung die Orientierung w{\"a}hrend des Kletterns, indem es einerseits Informationen vermittelt, die normalerweise nur visuell wahrgenommen werden k{\"o}nnen und andererseits dabei hilft, sich besser an bereits gekletterte Routen zu erinnern. Das System setzt sich aus 3 Komponenten zusammen. Die Tritthilfen helfen der blinden Person dabei, auch kleine Tritte zu finden. Die taktilen Wegmarken stellen eine Art Checkpoint dar und helfen der blinden Person dabei, die Route in mehrere Abschnitte zu unterteilen. Gleichzeitig weisen sie darauf hin, welches Feature die kletternde Person erwartet. Die taktile Karte ist modular aufgebaut und setzt sich aus einer Legende und den Repr{\"a}sentanten der Wegmarken einer Route zusammen. Analog zu dem Betrachten der Route ist die blinde Person so vor dem Klettern in der Lage, Informationen {\"u}ber die Route zu erfahren.}, language = {de} } @masterthesis{Hoffmann2023, type = {Bachelor Thesis}, author = {Hoffmann, Jan-Peter}, title = {Schl{\"u}ter Projekt X}, publisher = {FH Aachen}, address = {Aachen}, school = {Fachhochschule Aachen}, pages = {109 Seiten}, year = {2023}, abstract = {Schl{\"u}ter Projekt X ist die fiktive Reanimation des Traktorenherstellers Schl{\"u}ter. Dabei geht es darum, auf Basis der originalen Traktoren eine moderne Maschine zu entwerfen, welche die bew{\"a}hrte und beliebte Formsprache mit moderner Technologie und aktuellen Funktionen verbindet, um den Anforderungen der modernen Landwirtschaft gerecht zu werden. Dazu wurde Projekt X stark modular aufgebaut. Die Fahrzeugkabine l{\"a}sst sich um 180° drehen und gegebenenfalls durch ein vollkommen autonomes Modul austauschen. Die Reifen lassen sich bei Bedarf durch Ketten ersetzen. Projekt X wird elektronisch angetrieben, zur Vermeidung langer Ladezeiten l{\"a}sst sich der gesamte Akkublock in der Motorhaube austauschen.}, language = {de} } @article{EggertKling2023, author = {Eggert, Mathias and Kling, Rene}, title = {How to distribute charging requests of electronic vehicles? A reservation-based approach}, series = {International Journal of Intelligent Transportation Systems Research}, volume = {21}, journal = {International Journal of Intelligent Transportation Systems Research}, number = {2023}, publisher = {Springer}, address = {Berlin, Heidelberg, New York}, issn = {1868-8659}, doi = {10.1007/s13177-023-00367-z}, pages = {437 -- 460}, year = {2023}, abstract = {The number of electronic vehicles increase steadily while the space for extending the charging infrastructure is limited. In particular in urban areas, where parking spaces in attractive areas are famous, opportunities to setup new charging stations is very limited. This leads to an overload of some very attractive charging stations and an underutilization of less attractive ones. Against this background, the paper at hand presents the design of an e-vehicle reservation system that aims at distributing the utilization of the charging infrastructure, particularly in urban areas. By applying a design science approach, the requirements for a reservation-based utilization approach are elicited and a model for a suitable distribution approach and its instantiation are developed. The artefact is evaluated by simulating the distribution effects based on data of real charging station utilizations.}, language = {en} } @misc{OPUS4-10805, title = {Pr{\"u}fungsordnung f{\"u}r die Bachelorstudieng{\"a}nge „Biotechnologie" und „Biotechnologie mit Praxis- oder Auslandssemester" im Fachbereich Chemie und Biotechnologie an der FH Aachen}, address = {Aachen}, organization = {FH Aachen}, pages = {12 Seiten}, year = {2023}, abstract = {\S 1 | Geltungsbereich der Pr{\"u}fungsordnung \S 2 | Ziel des Studiums, Zweck der Pr{\"u}fung, Abschlussgrad \S 3 | Beginn, Dauer, Umfang und Gliederung des Studiums \S 4 | Zugang zum Studium, Praktikum \S 5 | Pr{\"u}fungsausschuss \S 6 | Studien- und Pr{\"u}fungselemente \S 7 | Zulassung zu den Pr{\"u}fungen \S 8 | Durchf{\"u}hrung von Pr{\"u}fungen \S 9 | Verbesserungsversuch \S 10 | Anrechnung von Studienzeiten, Studien- und Pr{\"u}fungsleistungen \S 11 | Praxissemester \S 12 | Mobilit{\"a}tssemester (Auslandssemester) \S 13 | Bachelorprojekt\S 14 | Gesamtnote, Zeugnis, Bachelorurkunde \S 15 | Inkrafttreten, Ver{\"o}ffentlichung Anlage 1 | Studienplan Kernstudium Anlage 2 | Allgemeine Kompetenzen}, language = {de} } @article{AdelsElbersDiehletal.2023, author = {Adels, Klaudia and Elbers, Gereon and Diehl, Bernd and Monakhova, Yulia}, title = {Multicomponent analysis of dietary supplements containing glucosamine and chondroitin: comparative low- and high-field NMR spectroscopic study}, series = {Analytical Sciences}, volume = {2023}, journal = {Analytical Sciences}, publisher = {Springer Verlag}, address = {Cham}, issn = {1348-2246 (Online)}, doi = {10.1007/s44211-023-00433-2}, pages = {13 Seiten}, year = {2023}, abstract = {With the prevalence of glucosamine- and chondroitin-containing dietary supplements for people with osteoarthritis in the marketplace, it is important to have an accurate and reproducible analytical method for the quantitation of these compounds in finished products. NMR spectroscopic method based both on low- (80 MHz) and high- (500-600 MHz) field NMR instrumentation was established, compared and validated for the determination of chondroitin sulfate and glucosamine in dietary supplements. The proposed method was applied for analysis of 20 different dietary supplements. In the majority of cases, quantification results obtained on the low-field NMR spectrometer are similar to those obtained with high-field 500-600 MHz NMR devices. Validation results in terms of accuracy, precision, reproducibility, limit of detection and recovery demonstrated that the developed method is fit for purpose for the marketed products. The NMR method was extended to the analysis of methylsulfonylmethane, adulterant maltodextrin, acetate and inorganic ions. Low-field NMR can be a quicker and cheaper alternative to more expensive high-field NMR measurements for quality control of the investigated dietary supplements. High-field NMR instrumentation can be more favorable for samples with complex composition due to better resolution, simultaneously giving the possibility of analysis of inorganic species such as potassium and chloride.}, language = {en} }