@article{DantismTakenagaWagneretal.2015,
  author    = {Dantism, S. and Takenaga, S. and Wagner, P. and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Light-addressable Potentiometric Sensor (LAPS) Combined with Multi-chamber Structures to Investigate the Metabolic Activity of Cells},
  series = {Procedia Engineering},
  volume    = {120},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2015.08.647},
  pages     = {384 -- 387},
  year      = {2015},
  abstract  = {LAPS are field-effect-based potentiometric sensors which are able to monitor analyte concentrations in a spatially resolved manner. Hence, a LAPS sensor system is a powerful device to record chemical imaging of the concentration of chemical species in an aqueous solution, chemical reactions, or the growth of cell colonies on the sensor surface, to record chemical images. In this work, multi-chamber 3D-printed structures made out of polymer (PP-ABS) were combined with LAPS chips to analyse differentially and simultaneously the metabolic activity of Escherichia coli K12 and Chinese hamster ovary (CHO) cells, and the responds of those cells to the addition of glucose solution.},
  language  = {en}
}
@article{MolinnusBaeckerSiegertetal.2015,
  author    = {Molinnus, Denise and B{\"a}cker, Matthias and Siegert, Petra and Willenberg, H. and Poghossian, Arshak and Keusgen, M. and Sch{\"o}ning, Michael Josef},
  title     = {Detection of Adrenaline Based on Substrate Recycling Amplification},
  series = {Procedia Engineering},
  volume    = {120},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2015.08.708},
  pages     = {540 -- 543},
  year      = {2015},
  abstract  = {An amperometric enzyme biosensor has been applied for the detection of adrenaline. The adrenaline biosensor has been prepared by modification of an oxygen electrode with the enzyme laccase that operates at a broad pH range between pH 3.5 to pH 8. The enzyme molecules were immobilized via cross-linking with glutaraldehyde. The sensitivity of the developed adrenaline biosensor in different pH buffer solutions has been studied.},
  language  = {en}
}
@article{SchusserKrischerMolinetal.2015,
  author    = {Schusser, Sebastian and Krischer, M. and Molin, D. G. M. and Akker, N. M. S. van den and B{\"a}cker, Matthias and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Sensor System for in-situ and Real-time Monitoring of Polymer (bio) degradation},
  series = {Procedia Engineering},
  volume    = {120},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2015.08.815},
  pages     = {948 -- 951},
  year      = {2015},
  abstract  = {A sensor system for investigating (bio)degradationprocesses of polymers is presented. The system utilizes semiconductor field-effect sensors and is capable of monitoring the degradation process in-situ and in real-time. The degradation of the polymer poly(d,l-lactic acid) is exemplarily monitored in solutions with different pH value, pH-buffer solution containing the model enzyme lipase from Rhizomucormiehei and cell-culture medium containing supernatants from stimulated and non-stimulated THP-1-derived macrophages mimicking activation of the immune system.},
  language  = {en}
}
@article{PilasMarianoKeusgenetal.2015,
  author    = {Pilas, Johanna and Mariano, K. and Keusgen, M. and Selmer, Thorsten and Sch{\"o}ning, Michael Josef},
  title     = {Optimization of an Enzyme-based Multi-parameter Biosensor for Monitoring Biogas Processes},
  series = {Procedia Engineering},
  volume    = {120},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2015.08.702},
  pages     = {532 -- 535},
  year      = {2015},
  language  = {en}
}
@article{MiyamotoBingWagneretal.2015,
  author    = {Miyamoto, Ko-ichiro and Bing, Yu and Wagner, Torsten and Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef},
  title     = {Visualization of Defects on a Cultured Cell Layer by Utilizing Chemical Imaging Sensor},
  series = {Procedia Engineering},
  volume    = {120},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2015.08.806},
  pages     = {936 -- 939},
  year      = {2015},
  abstract  = {The chemical imaging sensor is a field-effect sensor which is able to visualize both the distribution of ions (in LAPS mode) and the distribution of impedance (in SPIM mode) inthe sample. In this study, a novel wound-healing assay is proposed, in which the chemical imaging sensor operated in SPIM mode is applied to monitor the defect of a cell layer brought into proximity of the sensing surface.A reduced impedance inside the defect, which was artificially formed ina cell layer, was successfully visualized in a photocurrent image.},
  language  = {en}
}
@article{BronderPoghossianSchejaetal.2015,
  author    = {Bronder, Thomas and Poghossian, Arshak and Scheja, S. and Wu, Chunsheng and Keusgen, M. and Sch{\"o}ning, Michael Josef},
  title     = {Electrostatic Detection of Unlabelled Single- and Double-stranded DNA Using Capacitive Field-effect Devices Functionalized with a Positively Charged Polyelectrolyte Layer},
  series = {Procedia Engineering},
  volume    = {120},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2015.08.710},
  pages     = {544 -- 547},
  year      = {2015},
  abstract  = {Capacitive field-effect electrolyte-insulator-semiconductor sensors consisting of an Al-p-Si-SiO2 structure have been used for the electrical detection of unlabelled single- and double-stranded DNA (dsDNA) molecules by their intrinsic charge. A simple functionalization protocol based on the layer-by-layer (LbL) technique was used to prepare a weak polyelectrolyte/probe-DNA bilayer, followed by the hybridization with complementary target DNA molecules. Due to the flat orientation of the LbL-adsorbed DNA molecules, a high sensor signal has been achieved. In addition, direct label-free detection of in-solution hybridized dsDNA molecules has been studied.},
  language  = {en}
}
@inproceedings{FrotscherStaat2015,
  author    = {Frotscher, Ralf and Staat, Manfred},
  title     = {Homogenization of a cardiac tissue construct},
  series = {CMBE15 : 4th International Conference on Computational \& Mathematical Biomedical Engineering ; 29th June - 1st July 2015 ; {\´E}cole Normale Sup{\´e}rieure de Cachan ; Cachan (Paris), France},
  booktitle = {CMBE15 : 4th International Conference on Computational \& Mathematical Biomedical Engineering ; 29th June - 1st July 2015 ; {\´E}cole Normale Sup{\´e}rieure de Cachan ; Cachan (Paris), France},
  editor    = {Nithiarasu, Perumal},
  publisher = {CMBE},
  address   = {[s.l.]},
  issn      = {2227-9385},
  pages     = {645 -- 648},
  year      = {2015},
  language  = {en}
}
@inproceedings{WolfLenz2015,
  author    = {Wolf, Martin and Lenz, Laura L.},
  title     = {The economic effectiveness of serious games in the healthcare environment : application and evaluation of the Comparative Transformation Model (CTM)},
  series = {IEEE 3rd International Conference on Serious Games and Applications for Health : SeGAH 2014 ; Rio de Janeiro, Brazil, May 14 - 16},
  booktitle = {IEEE 3rd International Conference on Serious Games and Applications for Health : SeGAH 2014 ; Rio de Janeiro, Brazil, May 14 - 16},
  publisher = {IEEE [u.a.]},
  address   = {Piscataway, NJ},
  isbn      = {978-1-4799-4823-9},
  doi       = {10.1109/SeGAH.2014.7067089},
  pages     = {135 -- 142},
  year      = {2015},
  language  = {en}
}
@incollection{RahierRitzWallenborn2015,
  author    = {Rahier, Michael and Ritz, Thomas and Wallenborn, Ramona},
  title     = {Information and communication technology for integrated mobility concepts such as E-carsharing},
  series = {E-Mobility in Europe : trends and good practice},
  booktitle = {E-Mobility in Europe : trends and good practice},
  publisher = {Springer},
  address   = {Cham [u.a.]},
  isbn      = {978-3-319-13193-1},
  doi       = {10.1007/978-3-319-13194-8_17},
  pages     = {311 -- 326},
  year      = {2015},
  abstract  = {During the past decade attitude towards sharing things has changed extremely. Not just personal data is shared (e.g. in social networks) but also mobility. Together with the increased ecological awareness of the recent years, new mobility concepts have evolved. E-carsharing has become a symbol for these changes of attitude. The management of a shared car fleet, the energy management of electric mobility and the management of various carsharing users with individual likes and dislikes are just some of the major challenges of e-carsharing. Weaving it into integrated mobility concepts, this raises complexity even further. These challenges can only be overcome by an appropriate amount of well-shaped information available at the right place and time. In order to gather, process and share the required information, fleet cars have to be equipped with modern information and communication technology (ICT) and become so-called fully connected cars. Ensuring the usability of these ICT systems is another challenge that is often neglected, even though it is usability that makes carsharing comfortable, attractive and supports users' new attitudes. By means of an integrated and consistent concept for human-machine interaction (HMI), the usability of such systems can be raised tremendously.},
  language  = {en}
}
@incollection{BusseEschMuntaniol2015,
  author    = {Busse, Daniel and Esch, Thomas and Muntaniol, Roman},
  title     = {Thermal management in E-carsharing vehicles - preconditioning concepts of passenger compartments},
  series = {E-Mobility in Europe : trends and good practice},
  booktitle = {E-Mobility in Europe : trends and good practice},
  publisher = {Springer},
  address   = {Cham [u.a.]},
  isbn      = {978-3-319-13193-1},
  doi       = {10.1007/978-3-319-13194-8_18},
  pages     = {327 -- 343},
  year      = {2015},
  abstract  = {The issue of thermal management in electric vehicles includes the topics of drivetrain cooling and heating, interior temperature, vehicle body conditioning and safety. In addition to the need to ensure optimal thermal operating conditions of the drivetrain components (drive motor, battery and electrical components), thermal comfort must be provided for the passengers. Thermal comfort is defined as the feeling which expresses the satisfaction of the passengers with the ambient conditions in the compartment. The influencing factors on thermal comfort are the temperature and humidity as well as the speed of the indoor air and the clothing and the activity of the passengers, in addition to the thermal radiation and the temperatures of the interior surfaces. The generation and the maintenance of free visibility (ice- and moisture-free windows) count just as important as on-demand heating and cooling of the entire vehicle. A Carsharing climate concept of the innovative ec2go vehicle stipulates and allows for only seating areas used by passengers to be thermally conditioned in a close-to-body manner. To enable this, a particular feature has been added to the preconditioning of the Carsharing electric vehicle during the electric charging phase at the parking station.},
  language  = {en}
}