@article{HaegerJolmesOyenetal.2024,
  author    = {Haeger, Gerrit and Jolmes, Tristan and Oyen, Sven and Jaeger, Karl-Erich and Bongaerts, Johannes and Sch{\"o}rken, Ulrich and Siegert, Petra},
  title     = {Novel recombinant aminoacylase from Paraburkholderia monticola capable of N-acyl-amino acid synthesis},
  series = {Applied Microbiology and Biotechnology},
  journal   = {Applied Microbiology and Biotechnology},
  number    = {108},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1432-0614},
  doi       = {10.1007/s00253-023-12868-8},
  pages     = {14 Seiten},
  year      = {2024},
  abstract  = {N-Acyl-amino acids can act as mild biobased surfactants, which are used, e.g., in baby shampoos. However, their chemical synthesis needs acyl chlorides and does not meet sustainability criteria. Thus, the identification of biocatalysts to develop greener synthesis routes is desirable. We describe a novel aminoacylase from Paraburkholderia monticola DSM 100849 (PmAcy) which was identified, cloned, and evaluated for its N-acyl-amino acid synthesis potential. Soluble protein was obtained by expression in lactose autoinduction medium and co-expression of molecular chaperones GroEL/S. Strep-tag affinity purification enriched the enzyme 16-fold and yielded 15 mg pure enzyme from 100 mL of culture. Biochemical characterization revealed that PmAcy possesses beneficial traits for industrial application like high temperature and pH-stability. A heat activation of PmAcy was observed upon incubation at temperatures up to 80 °C. Hydrolytic activity of PmAcy was detected with several N-acyl-amino acids as substrates and exhibited the highest conversion rate of 773 U/mg with N-lauroyl-L-alanine at 75 °C. The enzyme preferred long-chain acyl-amino-acids and displayed hardly any activity with acetyl-amino acids. PmAcy was also capable of N-acyl-amino acid synthesis with good conversion rates. The best synthesis results were obtained with the cationic L-amino acids L-arginine and L-lysine as well as with L-leucine and L-phenylalanine. Exemplarily, L-phenylalanine was acylated with fatty acids of chain lengths from C8 to C18 with conversion rates of up to 75\%. N-lauroyl-L-phenylalanine was purified by precipitation, and the structure of the reaction product was verified by LC-MS and NMR.},
  language  = {en}
}
@book{ScheilenPeifferGoerlichetal.2023,
  author    = {Scheilen, Jana and Peiffer, Max and G{\"o}rlich, Anna-Luisa and Hacke, Theresa},
  title     = {Aachener Online-Schriften Wirtschaft und Recht. Band 7. 02/2023},
  editor    = {Kroll-Ludwigs, Kathrin and Bassen-Metz, Yasmine and Bernecker, Andreas and Eggert, Mathias and Fritz, Thomas and Golland, Alexander and H{\"o}hne, Tim and Tran, Duc Hung and Vogt, J{\"u}rgen},
  publisher = {FH Aachen / Fachbereich Wirtschaftswissenschaften},
  address   = {Aachen},
  publisher      = {Fachhochschule Aachen},
  pages     = {245 Seiten},
  year      = {2023},
  abstract  = {1. Die Wirksamkeitsvoraussetzungen der Verdachtsk{\"u}ndigung gegen{\"u}ber einem Arbeitnehmer - Jana Scheilen | Seite 4-66 2. Besteuerungsinkongruenzen im Internationalen Steuerrecht - die Umsetzung der ATAD II in Form des \S 4k EStG in Bezug auf hybride Gesellschaften und Betriebsst{\"a}tten - Max Peiffer | Seite 67-126 3. Der Zuzug einer Gesellschaft aus einem Drittstaat nach Deutschland - Herausforderungen durch die modifizierte Sitztheorie und L{\"o}sungsm{\"o}glichkeiten - Anna-Luisa G{\"o}rlich | Seite 127-189 4. Escalation of Commitment und seine Einflussfaktoren in der unternehmerischen Entscheidungsfindung: Ein Szenario-Experiment - Theresa Hacke | Seite 190-245},
  language  = {de}
}
@article{HammerQuitterMayntzetal.2023,
  author    = {Hammer, Thorben and Quitter, Julius and Mayntz, Joscha and Bauschat, J.-Michael and Dahmann, Peter and G{\"o}tten, Falk and Hille, S. and Stumpf, E.},
  title     = {Free fall drag estimation of small-scale multirotor unmanned aircraft systems using computational fluid dynamics and wind tunnel experiments},
  series = {CEAS Aeronautical Journal},
  journal   = {CEAS Aeronautical Journal},
  publisher = {Springer},
  address   = {Wien},
  issn      = {1869-5590 (Online)},
  doi       = {10.1007/s13272-023-00702-w},
  pages     = {14 Seiten},
  year      = {2023},
  abstract  = {New European Union (EU) regulations for UAS operations require an operational risk analysis, which includes an estimation of the potential danger of the UAS crashing. A key parameter for the potential ground risk is the kinetic impact energy of the UAS. The kinetic energy depends on the impact velocity of the UAS and, therefore, on the aerodynamic drag and the weight during free fall. Hence, estimating the impact energy of a UAS requires an accurate drag estimation of the UAS in that state. The paper at hand presents the aerodynamic drag estimation of small-scale multirotor UAS. Multirotor UAS of various sizes and configurations were analysed with a fully unsteady Reynolds-averaged Navier-Stokes approach. These simulations included different velocities and various fuselage pitch angles of the UAS. The results were compared against force measurements performed in a subsonic wind tunnel and provided good consistency. Furthermore, the influence of the UAS`s fuselage pitch angle as well as the influence of fixed and free spinning propellers on the aerodynamic drag was analysed. Free spinning propellers may increase the drag by up to 110\%, depending on the fuselage pitch angle. Increasing the fuselage pitch angle of the UAS lowers the drag by 40\% up to 85\%, depending on the UAS. The data presented in this paper allow for increased accuracy of ground risk assessments.},
  language  = {en}
}
@article{RichterBraunsteinStaeudleetal.2021,
  author    = {Richter, Charlotte and Braunstein, Bj{\"o}rn and St{\"a}udle, Benjamin and Attias, Julia and S{\"u}ss, Alexander and Weber, Tobias and Mileva, Katya N. and Rittweger, J{\"o}rn and Green, David A. and Albracht, Kirsten},
  title     = {Gastrocnemius medialis contractile behavior during running differs between simulated Lunar and Martian gravities},
  series = {Scientific reports},
  volume    = {11},
  journal   = {Scientific reports},
  number    = {Article number: 22555},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-021-00527-9},
  pages     = {13 Seiten},
  year      = {2021},
  abstract  = {The international partnership of space agencies has agreed to proceed forward to the Moon sustainably. Activities on the Lunar surface (0.16 g) will allow crewmembers to advance the exploration skills needed when expanding human presence to Mars (0.38 g). Whilst data from actual hypogravity activities are limited to the Apollo missions, simulation studies have indicated that ground reaction forces, mechanical work, muscle activation, and joint angles decrease with declining gravity level. However, these alterations in locomotion biomechanics do not necessarily scale to the gravity level, the reduction in gastrocnemius medialis activation even appears to level off around 0.2 g, while muscle activation pattern remains similar. Thus, it is difficult to predict whether gastrocnemius medialis contractile behavior during running on Moon will basically be the same as on Mars. Therefore, this study investigated lower limb joint kinematics and gastrocnemius medialis behavior during running at 1 g, simulated Martian gravity, and simulated Lunar gravity on the vertical treadmill facility. The results indicate that hypogravity-induced alterations in joint kinematics and contractile behavior still persist between simulated running on the Moon and Mars. This contrasts with the concept of a ceiling effect and should be carefully considered when evaluating exercise prescriptions and the transferability of locomotion practiced in Lunar gravity to Martian gravity.},
  language  = {en}
}
@misc{OPUS4-10850,
  title     = {Ordnung zur {\"A}nderung der Pr{\"u}fungsordnung f{\"u}r die Bachelorstudieng{\"a}nge „Schienenfahrzeugtechnik" „Schienenfahrzeugtechnik (Teilzeit)" und „Dualer Studiengang Schienenfahrzeugtechnik (DIRail)" im Fachbereich Maschinenbau und Mechatronik an der Fachhochschule Aachen},
  organization    = {FH Aachen},
  pages     = {2},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10851,
  title     = {Pr{\"u}fungsordnung f{\"u}r die Bachelorstudieng{\"a}nge „Schienenfahrzeugtechnik" „Schienenfahrzeugtechnik (Teilzeit)" und „Dualer Studiengang Schienenfahrzeugtechnik (DIRail)" im Fachbereich Maschinenbau und Mechatronik an der Fachhochschule Aachen},
  organization    = {FH Aachen},
  pages     = {14 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10862,
  title     = {Ordnung zur {\"A}nderung der Ordnung zur Aufhebung der Studien- und Pr{\"u}fungsordnung f{\"u}r den Masterstudiengang „Bauingenieurwesen" vom 10. Dezember 2012 (FH-Mitteilung Nr. 129/2012) in der Fassung der Bekanntmachung der {\"A}nderungsordnungen vom 30. Mai 2017 (FH-Mitteilung Nr. 58/2017) an der Fachhochschule Aachen},
  organization    = {FH Aachen},
  pages     = {2 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10864,
  title     = {Ordnung zur {\"A}nderung der Ordnung zur Aufhebung der Studien- und Pr{\"u}fungsordnung f{\"u}r den Masterstudiengang „Facility Management" vom 29. November 2012 (FH-Mitteilung Nr. 127/2012) in der Fassung der Bekanntmachung der {\"A}nderungsordnungen vom 3. Februar 2016 (FH-Mitteilung Nr. 10/2016) an der Fachhochschule Aachen},
  organization    = {FH Aachen},
  pages     = {2 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10865,
  title     = {Studien- und Pr{\"u}fungsordnung f{\"u}r den Bachelorstudiengang Bauingenieurwesen (7-semestrig), Bachelorstudiengang Bauingenieurwesen mit Praxissemester (8-semestrig) und Bachelorstudiengang Bauingenieurwesen mit Auslandssemester (8-semestrig) Abschluss Bachelor of Engineering},
  organization    = {FH Aachen},
  pages     = {26 Seiten},
  year      = {2019},
  language  = {de}
}
@misc{OPUS4-10873,
  title     = {Studien- und Pr{\"u}fungsordnung f{\"u}r den Bachelorstudiengang Bauingenieurwesen (7-semestrig), Bachelorstudiengang Bauingenieurwesen mit Praxissemester (8-semestrig), Bachelorstudiengang Bauingenieurwesen mit Auslandssemester (8-semestrig) Abschluss Bachelor of Engineering : vom 1. September 2011 - FH-Mitteilung Nr. 76/2011 in der Fassung der Bekanntmachung der {\"A}nderungsordnung vom 16. August 2019 - FH-Mitteilung Nr. 74/2019 (Nichtamtliche lesbare Fassung, Studienbeginn WS 2016/17-2017/18)},
  organization    = {FH Aachen},
  pages     = {30 Seiten},
  year      = {2019},
  language  = {de}
}