@inproceedings{WeldenSeverinsPoghossianetal.2022,
  author    = {Welden, Melanie and Severins, Robin and Poghossian, Arshak and Wege, Christina and Siegert, Petra and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Studying the immobilization of acetoin reductase with Tobacco mosaic virus particles on capacitive field-effect sensors},
  series = {2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)},
  booktitle = {2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)},
  publisher = {IEEE},
  isbn      = {978-1-6654-5860-3 (Online)},
  doi       = {10.1109/ISOEN54820.2022.9789657},
  pages     = {4 Seiten},
  year      = {2022},
  abstract  = {A capacitive electrolyte-insulator-semiconductor (EISCAP) biosensor modified with Tobacco mosaic virus (TMV) particles for the detection of acetoin is presented. The enzyme acetoin reductase (AR) was immobilized on the surface of the EISCAP using TMV particles as nanoscaffolds. The study focused on the optimization of the TMV-assisted AR immobilization on the Ta 2 O 5 -gate EISCAP surface. The TMV-assisted acetoin EISCAPs were electrochemically characterized by means of leakage-current, capacitance-voltage, and constant-capacitance measurements. The TMV-modified transducer surface was studied via scanning electron microscopy.},
  language  = {en}
}
@article{WeldenSeverinsPoghossianetal.2022,
  author    = {Welden, Melanie and Severins, Robin and Poghossian, Arshak and Wege, Christina and Bongaerts, Johannes and Siegert, Petra and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Detection of acetoin and diacetyl by a tobacco mosaic virus-assisted field-effect biosensor},
  series = {Chemosensors},
  volume    = {10},
  journal   = {Chemosensors},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2227-9040},
  doi       = {10.3390/chemosensors10060218},
  pages     = {Artikel 218},
  year      = {2022},
  abstract  = {Acetoin and diacetyl have a major impact on the flavor of alcoholic beverages such as wine or beer. Therefore, their measurement is important during the fermentation process. Until now, gas chromatographic techniques have typically been applied; however, these require expensive laboratory equipment and trained staff, and do not allow for online monitoring. In this work, a capacitive electrolyte-insulator-semiconductor sensor modified with tobacco mosaic virus (TMV) particles as enzyme nanocarriers for the detection of acetoin and diacetyl is presented. The enzyme acetoin reductase from Alkalihalobacillus clausii DSM 8716ᵀ is immobilized via biotin-streptavidin affinity, binding to the surface of the TMV particles. The TMV-assisted biosensor is electrochemically characterized by means of leakage-current, capacitance-voltage, and constant capacitance measurements. In this paper, the novel biosensor is studied regarding its sensitivity and long-term stability in buffer solution. Moreover, the TMV-assisted capacitive field-effect sensor is applied for the detection of diacetyl for the first time. The measurement of acetoin and diacetyl with the same sensor setup is demonstrated. Finally, the successive detection of acetoin and diacetyl in buffer and in diluted beer is studied by tuning the sensitivity of the biosensor using the pH value of the measurement solution.},
  language  = {en}
}
@article{HaegerBongaertsSiegert2022,
  author    = {Haeger, Gerrit and Bongaerts, Johannes and Siegert, Petra},
  title     = {A convenient ninhydrin assay in 96-well format for amino acid-releasing enzymes using an air-stable reagent},
  series = {Analytical Biochemistry},
  journal   = {Analytical Biochemistry},
  number    = {624},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1096-0309},
  doi       = {10.1016/j.ab.2022.114819},
  pages     = {Artikel 114819},
  year      = {2022},
  abstract  = {An improved and convenient ninhydrin assay for aminoacylase activity measurements was developed using the commercial EZ Nin™ reagent. Alternative reagents from literature were also evaluated and compared. The addition of DMSO to the reagent enhanced the solubility of Ruhemann's purple (RP). Furthermore, we found that the use of a basic, aqueous buffer enhances stability of RP. An acidic protocol for the quantification of lysine was developed by addition of glacial acetic acid. The assay allows for parallel processing in a 96-well format with measurements microtiter plates.},
  language  = {en}
}
@article{FalkenbergBottBongaertsetal.2022,
  author    = {Falkenberg, Fabian and Bott, Michael and Bongaerts, Johannes and Siegert, Petra},
  title     = {Phylogenetic survey of the subtilase family and a data-mining-based search for new subtilisins from Bacillaceae},
  series = {Frontiers in Microbiology},
  volume    = {2022},
  journal   = {Frontiers in Microbiology},
  number    = {13},
  publisher = {Frontiers},
  address   = {Lausanne},
  issn      = {1664-302X},
  doi       = {10.3389/fmicb.2022.1017978},
  pages     = {Artikel 13:1017978},
  year      = {2022},
  abstract  = {The subtilase family (S8), a member of the clan SB of serine proteases are ubiquitous in all kingdoms of life and fulfil different physiological functions. Subtilases are divided in several groups and especially subtilisins are of interest as they are used in various industrial sectors. Therefore, we searched for new subtilisin sequences of the family Bacillaceae using a data mining approach. The obtained 1,400 sequences were phylogenetically classified in the context of the subtilase family. This required an updated comprehensive overview of the different groups within this family. To fill this gap, we conducted a phylogenetic survey of the S8 family with characterised holotypes derived from the MEROPS database. The analysis revealed the presence of eight previously uncharacterised groups and 13 subgroups within the S8 family. The sequences that emerged from the data mining with the set filter parameters were mainly assigned to the subtilisin subgroups of true subtilisins, high-alkaline subtilisins, and phylogenetically intermediate subtilisins and represent an excellent source for new subtilisin candidates.},
  language  = {en}
}
@inproceedings{AltayButenwegKlinkel2014,
  author    = {Altay, Okyay and Butenweg, Christoph and Klinkel, Sven},
  title     = {Vibration mitigation of wind turbine towers by a new semiactive Tuned Liquid Column Damper},
  series = {6. Word Congress on Structural Control and Monitoring, 15 - 17 July, 2014 Barcelona,Spain},
  booktitle = {6. Word Congress on Structural Control and Monitoring, 15 - 17 July, 2014 Barcelona,Spain},
  year      = {2014},
  language  = {en}
}
@masterthesis{Dorn2023,
  type      = {Bachelor Thesis},
  author    = {Dorn, Aileen Sakura},
  title     = {Effizienz und Gesundheitsf{\"o}rderung im Krankenhaus : Dienstplanung im Krankenhaus unter Ber{\"u}cksichtigung der berufsbedingten psychischen und physischen Gesundheit des Klinikpersonals},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {133 Seiten},
  year      = {2023},
  abstract  = {Dass der Stress im Krankenhaus eine Belastung f{\"u}r das Klinikpersonal darstellt, ist eine allseits bekannte Tatsache. Das liegt an dem anstrengenden Klinikalltag, welcher die Mitarbeiter:innen auf Belastungsprobe stellt. Lange Dienste und {\"U}berstunden, wenig Pausen und hohe Arbeitsverdichtung, Nacht- und Schichtdienst, zudem auch die aufwendige Dokumentation und ̈B{\"u}rokratie. Timewise behandelt die Thematik der Dienstplanerstellung im Krankenhaus unter der Ber{\"u}cksichtigung der psychischen und physischen Gesundheit des Klinikpersonals im Nacht- und Schichtdienst. Essenzielle Funktionen sind k{\"u}rzere Kommunikationswege und eine gute {\"U}bersicht {\"u}ber den Soll-Ist-Abgleich inklusive {\"U}berstunden, Minusstunden, Abwesenheiten und den monatlichen Lohn. Der einfache Schichttausch und die Option der Ber{\"u}cksichtigung individueller Präferenzen und W{\"u}nsche ermöglicht es dem Personal, die Arbeit und das private Leben besser miteinander vereinen zu können, was sich positiv auf die Arbeitszufriedenheit auswirkt.},
  language  = {de}
}
@inproceedings{AltayButenwegKlinkel2013,
  author    = {Altay, Okyay and Butenweg, Christoph and Klinkel, Sven},
  title     = {Vibration control of slender structures by semi-active tuned liquid column dampers},
  series = {Conference of the ASCE Engineering Mechanics Institute , Evanston, IL , USA , EMI 2013 , 2013-08-04 - 2013-08-07},
  booktitle = {Conference of the ASCE Engineering Mechanics Institute , Evanston, IL , USA , EMI 2013 , 2013-08-04 - 2013-08-07},
  pages     = {1 Seite},
  year      = {2013},
  language  = {en}
}
@inproceedings{ButenwegNorda2013,
  author    = {Butenweg, Christoph and Norda, Hannah},
  title     = {Nonlinear analysis of masonry structures according to Eurocode 8},
  series = {Proceedings - Vienna Congress on Recent Advances in Earthquake Engineering and Structural Dynamics 2013 (VEESD 2013)},
  booktitle = {Proceedings - Vienna Congress on Recent Advances in Earthquake Engineering and Structural Dynamics 2013 (VEESD 2013)},
  editor    = {Adam, Christoph and Heuer, Rudolf and Lenhardt, Wolfgang and Schranz, Christian},
  isbn      = {978-3-902749-04-8},
  year      = {2013},
  language  = {en}
}
@inproceedings{ChurilovDumovaJovanoskaButenweg2013,
  author    = {Churilov, Sergej and Dumova-Jovanoska, Elena and Butenweg, Christoph},
  title     = {Seismic verification of existing masonry buildings and strengthening with reinforced concrete jackets},
  series = {Proceedings - Vienna Congress on Recent Advances in Earthquake Engineering and Structural Dynamics 2013 (VEESD 2013)},
  booktitle = {Proceedings - Vienna Congress on Recent Advances in Earthquake Engineering and Structural Dynamics 2013 (VEESD 2013)},
  editor    = {Adam, Christoph and Heuer, Rudolf and Lenhardt, Wolfgang and Schranz, Christian},
  isbn      = {978-3-902749-04-8},
  year      = {2013},
  abstract  = {A methodology for assessment, seismic verification and strengthening of existing masonry buildings is presented in this paper. The verification is performed using a calculation model calibrated with the results from ambient vibration measurements. The calibrated model serves as an input for a deformation-based verification procedure based on the Capacity Spectrum Method (CSM). The bearing capacity of the building is calculated from experimental capacity curves of the individual walls idealized with bilinear elastic-perfectly plastic curves. The experimental capacity curves were obtained from in-plane cyclic loading tests on unreinforced and strengthened masonry walls with reinforced concrete jackets. The seismic action is compared with the load-bearing capacity of the building considering non-linear material behavior with its post-peak capacity. The application of the CSM to masonry buildings and the influence of a traditional strengthening method are demonstrated on the example of a public school building in Skopje, Macedonia.},
  language  = {en}
}
@masterthesis{Donath2023,
  type      = {Bachelor Thesis},
  author    = {Donath, Paula},
  title     = {Die Hebamme : Portrait eines der {\"a}ltesten Berufe unserer Zeit},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {229 Seiten},
  year      = {2023},
  abstract  = {Seit Jahrhunderten tragen Hebammen die Verantwortung f{\"u}r neues Leben und geben ihre Erfahrungen und ihr K{\"o}nnen weiter. Trotz dieser ehrw{\"u}rdigen Aufgabe geh{\"o}ren sie zu einer kleinen Berufsgruppe, die viel zu oft untersch{\"a}tzt, {\"u}berlastet und unterbezahlt wird. Sie sind Begleiter*innen in einer der sensibelsten und emotionalsten Zeiten des Lebens. Die Unterst{\"u}tzung einer Hebamme gew{\"a}hrleistet Aufkl{\"a}rung und Beistand w{\"a}hrend der Schwangerschaft, der Geburt und der Zeit im Wochenbett. Das Projekt »Die Hebamme« ist ein Berufsportrait. Die Arbeit gibt Einblicke in die T{\"a}tigkeit und seine verschiedenen Bereiche und erz{\"a}hlt dabei haupts{\"a}chlich in Bildern. Zus{\"a}tzlich berichten Hebammen aus unterschiedlichen Blickwinkeln {\"u}ber ihre Arbeit. Dieses Portrait stellt die Realtit{\"a}t der Arbeit dar und soll die Bedeutung der T{\"a}tigkeit n{\"a}her bringen.},
  language  = {de}
}