@article{KurzLinderTrzewiketal.2010, author = {Kurz, R. and Linder, Peter and Trzewik, J{\"u}rgen and R{\"u}ffer, M. and Artmann, Gerhard and Digel, Ilya and Rothermel, A. and Robitzki, A. and Temiz Artmann, Ayseg{\"u}l}, title = {Contractile tension and beating rates of self-exciting monolayers and 3D-tissue constructs of neonatal rat cardiomyocytes}, series = {Medical and Biological Engineering and Computing}, volume = {48}, journal = {Medical and Biological Engineering and Computing}, number = {1}, publisher = {Springer Nature}, address = {Cham}, issn = {1741-0444}, doi = {10.1007/s11517-009-0552-y}, pages = {59 -- 65}, year = {2010}, abstract = {The CellDrum technology (The term 'CellDrum technology' includes a couple of slightly different technological setups for measuring lateral mechanical tension in various types of cell monolayers or 3D-tissue constructs) was designed to quantify the contraction rate and mechanical tension of self-exciting cardiac myocytes. Cells were grown either within flexible, circular collagen gels or as monolayer on top of respective 1-mum thin silicone membranes. Membrane and cells were bulged outwards by air pressure. This biaxial strain distribution is rather similar the beating, blood-filled heart. The setup allowed presetting the mechanical residual stress level externally by adjusting the centre deflection, thus, mimicking hypertension in vitro. Tension was measured as oscillating differential pressure change between chamber and environment. A 0.5-mm thick collagen-cardiac myocyte tissue construct induced after 2 days of culturing (initial cell density 2 x 10(4) cells/ml), a mechanical tension of 1.62 +/- 0.17 microN/mm(2). Mechanical load is an important growth regulator in the developing heart, and the orientation and alignment of cardiomyocytes is stress sensitive. Therefore, it was necessary to develop the CellDrum technology with its biaxial stress-strain distribution and defined mechanical boundary conditions. Cells were exposed to strain in two directions, radially and circumferentially, which is similar to biaxial loading in real heart tissues. Thus, from a biomechanical point of view, the system is preferable to previous setups based on uniaxial stretching.}, language = {en} } @article{BassamHeschelerTemizArtmannetal.2012, author = {Bassam, Rasha and Hescheler, J{\"u}rgen and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard and Digel, Ilya}, title = {Effects of spermine NONOate and ATP on the thermal stability of hemoglobin}, series = {BMC Biophysics}, volume = {5}, journal = {BMC Biophysics}, publisher = {BioMed Central}, address = {London}, issn = {2046-1682}, doi = {10.1186/2046-1682-5-16}, pages = {Art. 16}, year = {2012}, abstract = {Background Minor changes in protein structure induced by small organic and inorganic molecules can result in significant metabolic effects. The effects can be even more profound if the molecular players are chemically active and present in the cell in considerable amounts. The aim of our study was to investigate effects of a nitric oxide donor (spermine NONOate), ATP and sodium/potassium environment on the dynamics of thermal unfolding of human hemoglobin (Hb). The effect of these molecules was examined by means of circular dichroism spectrometry (CD) in the temperature range between 25°C and 70°C. The alpha-helical content of buffered hemoglobin samples (0.1 mg/ml) was estimated via ellipticity change measurements at a heating rate of 1°C/min. Results Major results were: 1) spermine NONOate persistently decreased the hemoglobin unfolding temperature T u irrespectively of the Na + /K + environment, 2) ATP instead increased the unfolding temperature by 3°C in both sodium-based and potassium-based buffers and 3) mutual effects of ATP and NO were strongly influenced by particular buffer ionic compositions. Moreover, the presence of potassium facilitated a partial unfolding of alpha-helical structures even at room temperature. Conclusion The obtained data might shed more light on molecular mechanisms and biophysics involved in the regulation of protein activity by small solutes in the cell.}, language = {en} } @article{Digel2008, author = {Digel, Ilya}, title = {Controlling microbial adhesion : a surface engineering approach}, series = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, journal = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, publisher = {Springer}, address = {Berlin [u.a.]}, isbn = {978-3-540-75408-4}, pages = {601 -- 625}, year = {2008}, language = {en} } @article{DigelTemizArtmann2011, author = {Digel, Ilya and Temiz Artmann, Ayseg{\"u}l}, title = {The emperor's new body : seeking for a blueprint of limb regeneration in humans}, series = {Stem cell engineering : principles and applications / Gerhard M. Artmann ... eds.}, journal = {Stem cell engineering : principles and applications / Gerhard M. Artmann ... eds.}, publisher = {Springer}, address = {Berlin [u.a.]}, isbn = {978-3-642-11864-7}, pages = {3 -- 37}, year = {2011}, language = {en} } @article{Digel2011, author = {Digel, Ilya}, title = {Primary thermosensory events in cells}, series = {Transient receptor potential channels / Md. Shahidul Islam, ed.}, journal = {Transient receptor potential channels / Md. Shahidul Islam, ed.}, publisher = {Springer}, address = {Dordrecht [u.a.]}, isbn = {978-94-007-0264-6}, pages = {451 -- 468}, year = {2011}, language = {en} } @article{Timme2012, author = {Timme, Michael}, title = {Die Reichweite der "werdenden" Wohnungseigent{\"u}mergemeinschaft gegen{\"u}ber dem Zweiterwerb}, series = {Monatsschrift f{\"u}r Deutsches Recht : MdR}, volume = {2012}, journal = {Monatsschrift f{\"u}r Deutsches Recht : MdR}, number = {18}, publisher = {Verlag Dr. Otto Schmidt}, address = {K{\"o}ln}, issn = {0340-1812}, doi = {10.9785/ovs-mdtr-2012-1069}, pages = {1068 -- 1071}, year = {2012}, abstract = {Mit einer aktuellen Entscheidung hat der BGH, Urt. v. 11.5.2012 - V ZR 196/11, MDR 2012, 958 seine Rechtsprechung v. 5.6.2008 - V ZB 85/07 zur Entstehungsphase einer Wohnungseigent{\"u}mergemeinschaft fortgef{\"u}hrt. In dieser Entscheidung sieht der BGH die Erwerber von Wohnungseigentum als Kostenschuldner gem. \S 16 Abs. 2 WEG an, obwohl diese noch nicht im Grundbuch eingetragen sind. Eine andere Rechtslage besteht beim sog. Zweiterwerb. Die Abgrenzung von Erstund Zweierwerb ist aufgrund der v{\"o}llig unterschiedlichen Rechtsfolgen f{\"u}r die Praxis von großer Bedeutung.}, language = {de} } @article{GutheilBergGrotendorst2012, author = {Gutheil, Inge and Berg, Tommy and Grotendorst, Johannes}, title = {Performance Analysis of Parallel Eigensolvers of two Libraries on BlueGene/P}, series = {Journal of Mathematics and Systems Science}, volume = {2}, journal = {Journal of Mathematics and Systems Science}, number = {4}, publisher = {David Publishing}, address = {Libertyville}, issn = {2159-5291}, doi = {10.17265/2159-5291/2012.04.003}, pages = {231 -- 236}, year = {2012}, abstract = {Many applications in computational science and engineering require the computation of eigenvalues and vectors of dense symmetric or Hermitian matrices. For example, in DFT (density functional theory) calculations on modern supercomputers 10\% to 30\% of the eigenvalues and eigenvectors of huge dense matrices have to be calculated. Therefore, performance and parallel scaling of the used eigensolvers is of upmost interest. In this article different routines of the linear algebra packages ScaLAPACK and Elemental for parallel solution of the symmetric eigenvalue problem are compared concerning their performance on the BlueGene/P supercomputer. Parameters for performance optimization are adjusted for the different data distribution methods used in the two libraries. It is found that for all test cases the new library Elemental which uses a two-dimensional element by element distribution of the matrices to the processors shows better performance than the old ScaLAPACK library which uses a block-cyclic distribution.}, language = {en} } @article{Grotendorst2012, author = {Grotendorst, Johannes}, title = {Supercomputer programmieren - ein besonderes Studienangebot in J{\"u}lich}, series = {Junge Wissenschaft. 27 (2012), H. 94}, journal = {Junge Wissenschaft. 27 (2012), H. 94}, publisher = {-}, isbn = {0179-8529}, pages = {12 -- 14}, year = {2012}, language = {de} } @article{Grotendorst2012, author = {Grotendorst, Johannes}, title = {IAS Winter School: Hierarchical Methods for Dynamics in Complex Molecular Systems}, series = {Innovatives Supercomputing in Deutschland : inSiDE. 10 (2012), H. 1}, journal = {Innovatives Supercomputing in Deutschland : inSiDE. 10 (2012), H. 1}, publisher = {-}, pages = {104}, year = {2012}, language = {en} } @article{Pfeiffer2003, author = {Pfeiffer, Johann}, title = {Lernfeld 'Prozeßkette der Freiformfl{\"a}chenherstellung' : [Online-Ressource] / ... in Zus.-Arb. mit Johann Pfeiffer}, series = {NUMAS - Ein Lehr- und Lernsystem zur Numerischen Mathematik und Statistik : [Online-Ressource] / Projektleitung: Gisela Engeln M{\"u}llges}, journal = {NUMAS - Ein Lehr- und Lernsystem zur Numerischen Mathematik und Statistik : [Online-Ressource] / Projektleitung: Gisela Engeln M{\"u}llges}, publisher = {NUMAS.de}, address = {Aachen}, year = {2003}, language = {de} } @article{Pfeiffer2004, author = {Pfeiffer, Johann}, title = {Genauigkeit und Qualit{\"a}t von Freiformfl{\"a}chen / Projektleiter: Joachim Gauchel}, series = {Forschungsbericht 2004 / Hrsg.: Der Rektor der Fachhochschule Aachen}, journal = {Forschungsbericht 2004 / Hrsg.: Der Rektor der Fachhochschule Aachen}, publisher = {Fachhochsch.}, address = {Aachen}, pages = {180}, year = {2004}, language = {de} } @article{Pfeiffer2002, author = {Pfeiffer, Johann}, title = {Gute Chancen im Maschinenbau}, series = {Rheinische Post : Sonderbeil. (2002)}, journal = {Rheinische Post : Sonderbeil. (2002)}, year = {2002}, language = {de} } @article{PfeifferGauchelLuecke1999, author = {Pfeiffer, Johann and Gauchel, Joachim and L{\"u}cke, Mathias}, title = {Genauigkeitsbetrachtungen in der CIM-Prozesskette}, series = {4th International Scientific Colloquium CAx Techniques : proceedings of the 4th international scientific colloquium, Fachhochschule Bielefeld, Germany, September 13 - 15, 1999 / [organized in co-operation between Fachhochschule Bielefeld and Rzesz{\´o}w University of Technology ]. Ed. by Heinrich Ostholt}, journal = {4th International Scientific Colloquium CAx Techniques : proceedings of the 4th international scientific colloquium, Fachhochschule Bielefeld, Germany, September 13 - 15, 1999 / [organized in co-operation between Fachhochschule Bielefeld and Rzesz{\´o}w University of Technology ]. Ed. by Heinrich Ostholt}, publisher = {[Fachhochsch.]}, address = {[Bielefeld]}, isbn = {3-00-004379-9}, pages = {323 -- 332}, year = {1999}, language = {de} } @article{Pfeiffer2002, author = {Pfeiffer, Johann}, title = {Chancen im Maschinenbau}, series = {Fachblatt : Journal der Fachhochschule Aachen . 2002 (2002), H. 1}, journal = {Fachblatt : Journal der Fachhochschule Aachen . 2002 (2002), H. 1}, publisher = {-}, pages = {2}, year = {2002}, language = {de} } @article{PfeifferGauchel1997, author = {Pfeiffer, Johann and Gauchel, Joachim}, title = {Entwicklung und Simulation von Mechanismen zu Automatisierungszwecken / Joachim Gauchel ; Johann Pfeiffer}, series = {CAE Techniques : [proceedings of the 3st International Scientific Colloquium, Rzesz{\´o}w University of Technology, Poland, September 24-27, 1997] / ed. by Kazimierz E. Oczoś}, journal = {CAE Techniques : [proceedings of the 3st International Scientific Colloquium, Rzesz{\´o}w University of Technology, Poland, September 24-27, 1997] / ed. by Kazimierz E. Oczoś}, publisher = {Politechnika Rzeszowska}, address = {Rzesz{\´o}w}, isbn = {83-7199-004-9}, pages = {425 ff}, year = {1997}, language = {de} } @article{Pfeiffer2002, author = {Pfeiffer, Johann}, title = {Gute Chancen im Maschinenbau}, series = {Aachener Nachrichten / Aachener Zeitung : Sonderbeil. (2002)}, journal = {Aachener Nachrichten / Aachener Zeitung : Sonderbeil. (2002)}, publisher = {-}, year = {2002}, language = {de} } @article{Frings2012, author = {Frings, Michael}, title = {Verbesserter Schutz vor Kostenfallen im elektronischen Gesch{\"a}ftsverkehr („Buttonl{\"o}sung") : Erster Schritt zur Umsetzung der neuen EU-Verbraucherrechterichtlinie}, series = {NWB : NWB-Steuer- und Wirtschaftsrecht}, volume = {2012}, journal = {NWB : NWB-Steuer- und Wirtschaftsrecht}, number = {23}, publisher = {NWB-Verlag}, address = {Herne}, issn = {0028-3460}, pages = {1912 -- 1918}, year = {2012}, abstract = {Der Deutsche Bundestag und Bundesrat haben am 2.3.2012 bzw. 30.3.2012 das Gesetz gegen Kostenfallen im Internet verabschiedet, das am 1.8.2012 in Kraft treten wird. Hiermit hat der deutsche Gesetzgeber einen ersten Schritt getan, um die neue EU-Verbraucherrechterichtlinie vom 25.10.2011 (2011/83/EU, ABl L 304/64) in nationales Recht umzusetzen. Mit dieser Umsetzung ist das dr{\"a}ngendste Problem der Kosten- und Abo-Fallen im elektronischen Gesch{\"a}ftsverkehr aus dem Gesamtpaket der Verbraucherrechterichtlinie herausgel{\"o}st und in dem neugefassten \S 312g BGB behandelt worden. Eile bei der Umsetzung war hier geboten, weil unseri{\"o}se Unternehmen im elektronischen Rechtsverkehr zunehmend und in großem Umfang gegen{\"u}ber ihren Kunden durch irref{\"u}hrende Gestaltungen ihrer Internetseiten verschleiern, dass die angebotenen Leistungen entgeltpflichtig sind.}, language = {de} } @article{BohrnStuetzFleischeretal.2013, author = {Bohrn, Ulrich and St{\"u}tz, Evamaria and Fleischer, Maximilian and Sch{\"o}ning, Michael Josef and Wagner, Patrick}, title = {Using a cell-based gas biosensor for investigation of adverse effects of acetone vapors in vitro}, series = {Biosensors and Bioelectronics. 40 (2013), H. 1}, journal = {Biosensors and Bioelectronics. 40 (2013), H. 1}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0956-5663}, pages = {393 -- 400}, year = {2013}, language = {en} } @article{AtlasBrealeyDharetal.2012, author = {Atlas, Glen and Brealey, David and Dhar, Sunil and Dikta, Gerhard and Singer, Meryvn}, title = {Additional hemodynamic measurements with an esophageal Doppler monitor: a preliminary report of compliance, force, kinetic energy, and afterload in the clinical setting}, series = {Journal of clinical monitoring and computing}, journal = {Journal of clinical monitoring and computing}, number = {26}, publisher = {Springer Nature}, address = {London}, isbn = {1573-2614}, doi = {10.1007/s10877-012-9386-5}, pages = {473 -- 482}, year = {2012}, abstract = {The esophageal Doppler monitor (EDM) is a minimally-invasive hemodynamic device which evaluates both cardiac output (CO), and fluid status, by estimating stroke volume (SV) and calculating heart rate (HR). The measurement of these parameters is based upon a continuous and accurate approximation of distal thoracic aortic blood flow. Furthermore, the peak velocity (PV) and mean acceleration (MA), of aortic blood flow at this anatomic location, are also determined by the EDM. The purpose of this preliminary report is to examine additional clinical hemodynamic calculations of: compliance (C), kinetic energy (KE), force (F), and afterload (TSVRi). These data were derived using both velocity-based measurements, provided by the EDM, as well as other contemporaneous physiologic parameters. Data were obtained from anesthetized patients undergoing surgery or who were in a critical care unit. A graphical inspection of these measurements is presented and discussed with respect to each patient's clinical situation. When normalized to each of their initial values, F and KE both consistently demonstrated more discriminative power than either PV or MA. The EDM offers additional applications for hemodynamic monitoring. Further research regarding the accuracy, utility, and limitations of these parameters is therefore indicated.}, language = {en} } @article{Frings2012, author = {Frings, Michael}, title = {Immobilienfinanzierung und Verbraucherkredit : Das neue Verbraucherkreditrecht nach der Verbraucherkreditrichtlinie}, series = {NWB : Steuer- und Wirtschaftsrecht}, volume = {2012}, journal = {NWB : Steuer- und Wirtschaftsrecht}, number = {15}, publisher = {NWB-Verlag}, address = {Herne}, issn = {0028-3460}, pages = {1237 -- 1247}, year = {2012}, abstract = {Mit Gesetz vom 29.7.2009 (BGBl 2009 I S. 2355) hat der deutsche Gesetzgeber die EU-Verbraucherkreditrichtlinie 2008/48/EG vom 23.4.2008 NWB PAAAD-28762 in nationales Recht umgesetzt. In diesem Gesetz ist auch der Immobiliardarlehensvertrag neu geregelt worden. Auf diese besondere Kreditform sind grds. die Vorschriften zum Verbraucherkredit anzuwenden, so dass der Darlehensgeber auch im Fall einer Immobilienfinanzierung zu vorvertraglicher Information des Verbrauchers verpflichtet ist. Beim finanzierten Immobilienerwerb werden Ver{\"a}ußerer und kreditgebende Bank h{\"a}ufig in Abstimmung und Zusammenarbeit t{\"a}tig, so dass f{\"u}r die Bank besondere Aufkl{\"a}rungspflichten gegen{\"u}ber dem Verbraucher entstehen. Im Fall der Verletzung dieser Pflichten drohen ihr Schadensersatzanspr{\"u}che oder ein Widerrufsrecht des Verbrauchers.}, language = {de} } @article{KirchnerOberlaenderFriedrichetal.2012, author = {Kirchner, Patrick and Oberl{\"a}nder, Jan and Friedrich, Peter and Berger, J{\"o}rg and Rysstad, Gunnar and Sch{\"o}ning, Michael Josef and Keusgen, Michael}, title = {Realisation of a calorimetric gas sensor on polyimide foil for applications in aseptic food industry}, series = {Sensors and Actuators B: Chemical}, volume = {170}, journal = {Sensors and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2011.01.032}, pages = {60 -- 66}, year = {2012}, abstract = {A calorimetric gas sensor is presented for the monitoring of vapour-phase H2O2 at elevated temperature during sterilisation processes in aseptic food industry. The sensor was built up on a flexible polyimide foil (thickness: 25 μm) that has been chosen due to its thermal stability and low thermal conductivity. The sensor set-up consists of two temperature-sensitive platinum thin-film resistances passivated by a layer of SU-8 photo resist and catalytically activated by manganese(IV) oxide. Instead of an active heating structure, the calorimetric sensor utilises the elevated temperature of the evaporated H2O2 aerosol. In an experimental test rig, the sensor has shown a sensitivity of 4.78 °C/(\%, v/v) in a H2O2 concentration range of 0\%, v/v to 8\%, v/v. Furthermore, the sensor possesses the same, unchanged sensor signal even at varied medium temperatures between 210 °C and 270 °C of the gas stream. At flow rates of the gas stream from 8 m3/h to 12 m3/h, the sensor has shown only a slightly reduced sensitivity at a low flow rate of 8 m3/h. The sensor characterisation demonstrates the suitability of the calorimetric gas sensor for monitoring the efficiency of industrial sterilisation processes.}, language = {en} } @article{SchusserPoghossianBaeckeretal.2012, author = {Schusser, Sebastian and Poghossian, Arshak and B{\"a}cker, Matthias and Leinhos, Marcel and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Characterization of biodegradable polymers with capacitive field-effect sensors}, series = {Sensors and actuators B: Chemical}, volume = {187}, journal = {Sensors and actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2012.07.099}, pages = {2 -- 7}, year = {2012}, abstract = {In vitro studies of the degradation kinetic of biopolymers are essential for the design and optimization of implantable biomedical devices. In the presented work, a field-effect capacitive sensor has been applied for the real-time and in situ monitoring of degradation processes of biopolymers for the first time. The polymer-covered field-effect sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. The feasibility of this approach has been experimentally proven by using the commercially available biomedical polymer poly(D,L-lactic acid) (PDLLA) as a model system. PDLLA films of different thicknesses were deposited on the Ta₂O₅-gate surface of the field-effect structure from a polymer solution by means of spin-coating method. The polymer-modified field-effect sensors have been characterized by means of capacitance-voltage and impedance-spectroscopy method. The degradation of the PDLLA was accelerated by changing the degradation medium from neutral (pH 7.2) to alkaline (pH 9) condition, resulting in drastic changes in the capacitance and impedance spectra of the polymer-modified field-effect sensor.}, language = {en} } @article{KotliarSvetlovaStegaevetal.2004, author = {Kotliar, Konstantin and Svetlova, O. V. and Stegaev, V. A. and Parkhomov, S. D.}, title = {Biomechanical substantiation of relatively low efficiency of recurrent laser trabeculoplasty / Svetlova, O. V. ; Stagaev, V. A. ; Parkhomov, S. D. ; Kotliar, K. E. ; Makarov, F. N. ; Smolnikov, B. A. ; Koshitz, I. N.}, series = {Glaukoma (2004)}, journal = {Glaukoma (2004)}, publisher = {-}, pages = {29 -- 39}, year = {2004}, language = {en} } @article{KotliarSvetlovaSourjikovetal.2004, author = {Kotliar, Konstantin and Svetlova, O. V. and Sourjikov, A. V. and Zaseeva, M. V.}, title = {Biomechanical peculiarities of aqueous humor production system and outflow regulation system / Svetlova, O. V. ; Sourjikov, A. V. ; Kotliar, K. E. ; Zaseeva, M. V. ; Shukhaev, S. V. ; Koshitz, I. N.}, series = {Glaukoma (2004)}, journal = {Glaukoma (2004)}, publisher = {-}, pages = {66 -- 76}, year = {2004}, language = {en} } @article{MiyamotoKanekoMatsuoetal.2012, author = {Miyamoto, Ko-ichiro and Kaneko, Kazumi and Matsuo, Akira and Wagner, Torsten and Kanoh, Shin{\´i}chiro and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Miniaturized chemical imaging sensor system using an OLED display panel}, series = {Sensors and Actuators B: Chemical}, volume = {170}, journal = {Sensors and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2011.02.029}, pages = {82 -- 87}, year = {2012}, abstract = {The chemical imaging sensor is a semiconductor-based chemical sensor that can visualize the two-dimensional distribution of specific ions or molecules in the solution. In this study, we developed a miniaturized chemical imaging sensor system with an OLED display panel as a light source that scans the sensor plate. In the proposed configuration, the display panel is placed directly below the sensor plate and illuminates the back surface. The measured area defined by illumination can be arbitrarily customized to fit the size and the shape of the sample to be measured. The waveform of the generated photocurrent, the current-voltage characteristics and the pH sensitivity were investigated and pH imaging with this miniaturized system was demonstrated.}, language = {en} } @article{KotliarKoshitzSvetlowaetal.2006, author = {Kotliar, Konstantin and Koshitz, I. N. and Svetlowa, O. V. and Zaseeva, M. V.}, title = {Physiological principles of hypotensive therapy of open-angle glaucoma during presbyopic period. Part II Promising algorithms of practical sparing applications / Koshitz, I. N. ; Svetlova, O. V. ; Zaseeva, M. V. ; Shuhaev, S. V. ; Makarov, F. N. ; Kotliar}, series = {Glaukoma (2006)}, journal = {Glaukoma (2006)}, publisher = {-}, pages = {51 -- 70}, year = {2006}, language = {en} } @article{KotliarKoshitzSvetlowaetal.2005, author = {Kotliar, Konstantin and Koshitz, I. N. and Svetlowa, O. V. and Makarov, F. N.}, title = {Biomechanical analysis of traditional and contemporary conceptions on pathogenesis of the primary open angle glaucoma / Koshitz, I. N. ; Svetlova, O. V. ; Kotliar, K. E. ; Makarov, F. N. ; Smolnikov, B. A.}, series = {Glaukoma (2005)}, journal = {Glaukoma (2005)}, publisher = {-}, pages = {41 -- 63}, year = {2005}, language = {en} } @article{KotliarKoshitzSvetlovaetal.2006, author = {Kotliar, Konstantin and Koshitz, I. N. and Svetlova, O. V. and Zaseeva, M. V.}, title = {Physiological principles of hypotensive therapy of open-angle glaucoma during presbyopic period. Part I Initial theoretical presuppositions, hypotheses and facts / Koshitz, I. N. ; Svetlova, O. V. ; Zaseeva, M. V. ; Shuhaev, S. V. ; Makarov, F. N. ; Kotli}, series = {Glaukoma (2006)}, journal = {Glaukoma (2006)}, publisher = {-}, pages = {35 -- 53}, year = {2006}, language = {en} } @article{KotliarSvetlovaZinoviewaetal.2001, author = {Kotliar, Konstantin and Svetlova, O. V. and Zinoviewa, N. V. and Krylova, I. S.}, title = {Elaboration of the conception of the biomechanical model of the aqueous intraocular outflow / Svetlova, O. V. ; Zinoviewa, N. V. ; Krylova, I. S. ; Koshitz, I. N. ; Smolnikov, B. A. ; Fedorova, E. M. ; Kotliar, K. E.}, series = {Rossiiskii zhurnal biomekhaniki = Russian Journal of biomechanics. 5 (2001), H. 3}, journal = {Rossiiskii zhurnal biomekhaniki = Russian Journal of biomechanics. 5 (2001), H. 3}, publisher = {-}, isbn = {1812-5123}, pages = {23 -- 27}, year = {2001}, language = {en} } @article{KotliarLanzlWittaetal.2000, author = {Kotliar, Konstantin and Lanzl, Ines M. and Witta, Birka and Vilser, Walthard}, title = {Reaktion retinaler Gef{\"a}ßdurchmesser auf 100 \% O2-Atmung - funktionelle Messung mit dem Retinal Vessel Analyzer an 10 Probanden / Lanzl, Ines M. ; Witta, Birke ; Kotliar, Konstantin ; Vilser, Walthard}, series = {Klinische Monatsbl{\"a}tter f{\"u}r Augenheilkunde. 217 (2000), H. 4}, journal = {Klinische Monatsbl{\"a}tter f{\"u}r Augenheilkunde. 217 (2000), H. 4}, publisher = {-}, isbn = {1439-3999}, pages = {231 -- 235}, year = {2000}, language = {de} } @article{KotliarLanzlMaieretal.2008, author = {Kotliar, Konstantin and Lanzl, Ines M. and Maier, Mathias and Feucht, Nikolaus}, title = {Intraocular pressure effects of pegaptanib (macugen) injections in patients with and without glaucoma / Lanzl, Ines M. ; Maier, Mathias ; Feucht, Nikolaus ; Lohmann, Chris P. ; Kotliar, Konstantin E.}, series = {American Journal of Ophthalmology . 145 (2008), H. 1}, journal = {American Journal of Ophthalmology . 145 (2008), H. 1}, publisher = {-}, isbn = {1879-1891}, pages = {185 -- 185}, year = {2008}, language = {en} } @article{KotliarVilserNageletal.2004, author = {Kotliar, Konstantin and Vilser, Walthatd and Nagel, Edgar and Lanzl, Ines M.}, title = {Retinal vessel reaction in response to chromatic flickering light / Kotliar, Konstantin E. ; Vilser, Walthard ; Nagel, Edgar ; Lanzl, Ines M.}, series = {Graefe's Archive for Clinical and Experimental Ophthalmology. 242 (2004), H. 5}, journal = {Graefe's Archive for Clinical and Experimental Ophthalmology. 242 (2004), H. 5}, publisher = {-}, isbn = {1435-702X}, pages = {377 -- 392}, year = {2004}, language = {en} } @article{KotliarBauerZamuraev2006, author = {Kotliar, Konstantin and Bauer, S. M. and Zamuraev, L. A.}, title = {Model of the transversely isotropic spherical layer for estimation of intraocular pressure changes after intravitreal injections / Bauer, S. M. ; Zamuraev, L. A. ; Kotliar, K. E.}, series = {Rossiiskii zhurnal biomekhaniki = Russian Journal of biomechanics. 10 (2006), H. 2}, journal = {Rossiiskii zhurnal biomekhaniki = Russian Journal of biomechanics. 10 (2006), H. 2}, publisher = {-}, isbn = {1812-5123}, pages = {41 -- 47}, year = {2006}, language = {en} } @article{GarhoferBekBoehmetal.2010, author = {Garhofer, Gerhard and Bek, Toke and Boehm, Andreas G. and Gherghel, Doina and Grundwald, Juan and Jeppesen, Peter and Kergoat, H{\´e}l{\`e}ne and Kotliar, Konstantin and Lanzl, Ines and Lovasik, John V. and Nagel, Edgar and Vilser, Walthard and Orgul, Selim and Schmetterer, Leopold}, title = {Use of the retinal vessel analyzer in ocular blood flow research}, series = {Acta Ophthalmol}, volume = {88}, journal = {Acta Ophthalmol}, number = {7}, publisher = {Wiley-Blackwell}, address = {Oxford}, issn = {1755-3768}, doi = {10.1111/j.1755-3768.2009.01587.x}, pages = {717 -- 722}, year = {2010}, abstract = {The present article describes a standard instrument for the continuous online determination of retinal vessel diameters, the commercially available retinal vessel analyzer. This report is intended to provide informed guidelines for measuring ocular blood flow with this system. The report describes the principles underlying the method and the instruments currently available, and discusses clinical protocol and the specific parameters measured by the system. Unresolved questions and the possible limitations of the technique are also discussed.}, language = {en} } @article{KotliarKozlovaLanzl2009, author = {Kotliar, Konstantin and Kozlova, Tatiana V. and Lanzl, Ines M.}, title = {Postoperative aqueous outflow in the human eye after glaucoma filtration surgery: biofluidmechanical considerations}, series = {Biomedizinische Technik = Biomedical Engineering}, volume = {54}, journal = {Biomedizinische Technik = Biomedical Engineering}, number = {1}, publisher = {-}, isbn = {1862-278X}, pages = {14 -- 22}, year = {2009}, language = {en} } @article{SeidovaKotliarFoergeretal.2009, author = {Seidova, Seid-Fatima and Kotliar, Konstantin and Foerger, Frauke and Klopfer, Matthias and Lanzl, Ines}, title = {Functional retinal changes in Gaucher disease}, series = {Documenta Ophthalmologica}, volume = {118}, journal = {Documenta Ophthalmologica}, number = {2}, publisher = {Springer}, address = {Berlin}, isbn = {1573-2622}, pages = {151 -- 154}, year = {2009}, language = {en} } @article{BaumannSchwarzKotliaretal.2009, author = {Baumann, Marcus and Schwarz, Sonja and Kotliar, Konstantin and Eynatten, Maximilian von and Trucksaess, Arno and Burckhardt, Klaus and Lutz, Jens and Heemann, Uwe and Lanzl, Ines}, title = {Non-diabetic chronic kidney disease influences retinal microvasculature}, series = {Kidney and Blood Pressure Research}, volume = {32}, journal = {Kidney and Blood Pressure Research}, number = {6}, publisher = {-}, isbn = {1423-0143}, pages = {428 -- 433}, year = {2009}, language = {en} } @article{BurkhardtSchwarzPanetal.2009, author = {Burkhardt, Klaus and Schwarz, Sonja and Pan, Chengrui and Stelter, Felix and Kotliar, Konstantin and Eynatten, Maxilian von and Sollinger, Daniel and Lanzl, Ines and Heemann, Uwe and Baumann, Marcus}, title = {Myeloid-related protein 8/14 complex describes microcirculatory alterations in patients with type 2 diabetes and nephropathy}, series = {Cardiovascular Diabetology}, volume = {8}, journal = {Cardiovascular Diabetology}, number = {10}, publisher = {-}, isbn = {1475-2840}, pages = {1 -- 8}, year = {2009}, language = {en} } @article{KotliarBaumannVilseretal.2011, author = {Kotliar, Konstantin and Baumann, Marcus and Vilser, Walthard and Lanzl, Ines M.}, title = {Pulse wave velocity in retinal arteries of healthy volunteers}, series = {British Journal of Ophthalmology (eBJO)}, volume = {95}, journal = {British Journal of Ophthalmology (eBJO)}, number = {11}, publisher = {BMJ Publ. Group}, address = {London}, isbn = {1468-2079}, pages = {675 -- 679}, year = {2011}, language = {en} } @article{KotliarLanzlSchmidtTrucksaessetal.2011, author = {Kotliar, Konstantin and Lanzl, Ines M. and Schmidt-Trucks{\"a}ss, A. and Sitnikova, Diana and Ali, Mohammad and Blume, Katharina and Halle, Martin and Hansser, Henner}, title = {Dynamic retinal vessel response to flicker in obesity: A methodological approach}, series = {Microvascular Research}, volume = {81}, journal = {Microvascular Research}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0026-2862}, pages = {123 -- 128}, year = {2011}, language = {en} } @article{DashevskyLanzlKotliar2011, author = {Dashevsky, Alexey V. and Lanzl, Ines M. and Kotliar, Konstantin}, title = {Non-penetrating intracanalicular partial trabeculectomy via the ostia of Schlemm's canal}, series = {Graefe's Archive for Clinical and Experimental Ophthalmology}, volume = {249}, journal = {Graefe's Archive for Clinical and Experimental Ophthalmology}, number = {4}, publisher = {Springer}, address = {Berlin}, issn = {0721-832x}, pages = {565 -- 573}, year = {2011}, language = {en} } @article{MaierFeuchtWinklervonMohrenfelsetal.2011, author = {Maier, M. M. and Feucht, N. and Winkler von Mohrenfels, C. and Kotliar, Konstantin and Fabian, E. and Lohmann, C. P.}, title = {Nahtlose Cerclage mit Skleratunnelfixation. Sutureless Encircling Band - Clinical Experience}, series = {Klinische Monatsbl{\"a}tter f{\"u}r Augenheilkunde}, volume = {228}, journal = {Klinische Monatsbl{\"a}tter f{\"u}r Augenheilkunde}, number = {5}, publisher = {Thieme}, address = {Stuttgart}, isbn = {0344-6360}, pages = {473 -- 476}, year = {2011}, language = {de} } @article{PresslerEsefeldScherretal.2010, author = {Pressler, Axel and Esefeld, Katrin and Scherr, Johannes and Ali, Mohammad and Hanssen, Henner and Kotliar, Konstantin and Lanzl, Ines and Halle, Martin and Kaemmerer, Harald and Schmidt-Trucks{\"a}ss, Arno and Hager, Alfred}, title = {Structural alterations of retinal arterioles in adults late after repair of aortic isthmic coarctation}, series = {The American Journal of Cardiology}, volume = {105}, journal = {The American Journal of Cardiology}, number = {5}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0002-9149}, doi = {10.1016/j.amjcard.2009.10.070}, pages = {740 -- 744}, year = {2010}, abstract = {Patients after coarctation repair still have an increased risk of cardiovascular or cerebrovascular events. This has been explained by the persisting hypertension and alterations in the peripheral vessels. However, involvement of the central vessels such as the retinal arteries is virtually unknown. A total of 34 patients after coarctation repair (22 men and 12 women; 23 to 58 years old, age range 0 to 32 years at surgical repair) and 34 nonhypertensive controls underwent structural and functional retinal vessel analysis. Using structural analysis, the vessel diameters were measured. Using functional analysis, the endothelium-dependent vessel dilation in response to flicker light stimulation was assessed. In the patients after coarctation repair, the retinal arteriolar diameter was significantly reduced compared to that of the controls (median 182 μm, first to third quartile 171 to 197; vs 197 μm, first to third quartile 193 to 206; p <0.001). These findings were independent of the peripheral blood pressure and age at intervention. No differences were found for venules. The functional analysis findings were not different between the patients and controls (maximum dilation 3.5\%, first to third quartile 2.1\% to 4.5\% vs 3.6\%, first to third quartile 2.2\% to 4.3\%; p = 0.81), indicating preserved autoregulative mechanisms. In conclusion, the retinal artery diameter is reduced in patients after coarctation repair, independent of their current blood pressure level and age at intervention. As a structural marker of chronic vessel damage associated with past, current, or future hypertension, retinal arteriolar narrowing has been linked to stroke incidence. These results indicate an involvement of cerebral microcirculation in aortic coarctation, despite timely repair, and might contribute to explain the increased rate of cerebrovascular events in such patients.}, language = {en} } @article{MikielewiczKotliarBarraqueretal.2011, author = {Mikielewicz, Marek and Kotliar, Konstantin and Barraquer, Rafael I. and Michael, Ralph}, title = {Air-pulse corneal applanation signal curve parameters for the characterisation of keratoconus}, series = {British Journal of Ophthalmology (eBJO)}, volume = {95}, journal = {British Journal of Ophthalmology (eBJO)}, number = {6}, publisher = {BMJ Publ. Group}, address = {London}, issn = {1468-2079}, pages = {793 -- 798}, year = {2011}, language = {en} } @article{KotliarMogilevskiĭShiloetal.2008, author = {Kotliar, Konstantin and Mogilevskiĭ, A. Ia. and Shilo, A. V. and Panchekha, A. P.}, title = {[Chaotic non-linear dynamics of alpha-band of the EEg and organization of the cortical activity of P300 wave] / Mogilevskiĭ, A. Ia. ; Kotliar, K. E. ; Shilo, A. V. ; Panchekha, A. P.}, series = {Zhurnal vyssheĭ nervnoĭ deiatelnosti imeni I P Pavlova. 58 (2008), H. 5}, journal = {Zhurnal vyssheĭ nervnoĭ deiatelnosti imeni I P Pavlova. 58 (2008), H. 5}, publisher = {-}, isbn = {0044-4677}, pages = {562 -- 575}, year = {2008}, language = {en} } @article{KotliarSvetlovaMakarovetal.2003, author = {Kotliar, Konstantin and Svetlova, O. V. and Makarov, F. N. and Zaseeva, M. V.}, title = {Morfologicheskie i funktsional'nye osobennosti resnichnogo poiaska khrustalika kak kliuchevogo ispolnitel'nogo zvena v mekhanizme akkommodatsii glaza cheloveka = Morpho-functional characteristics of lens ciliary body as a key mechanism of accommodation in}, series = {Morfologiia (Saint Petersburg, Russia). 123 (2003), H. 3}, journal = {Morfologiia (Saint Petersburg, Russia). 123 (2003), H. 3}, publisher = {-}, isbn = {1026-3543}, pages = {7 -- 16}, year = {2003}, language = {en} } @article{KotliarVolkovKoshitsetal.1997, author = {Kotliar, Konstantin and Volkov, V. V. and Koshits, I. N. and Svetlova, O. V.}, title = {Biomekhanicheskie osobennosti vzaimodeĭstviia drenazhno i akkomodatsionnoĭ reguliatornykh sistem glaza v norme i pri kontuzionnom podvyvikhe khrustalika / Volkov, V. V. ; Kotliar, K. E. ; Koshits, I. n. ; Svetlova, O. V. ; Smol´nikov, B. A.}, series = {Vestnik oftalmologii. 113 (1997), H. 3}, journal = {Vestnik oftalmologii. 113 (1997), H. 3}, publisher = {-}, isbn = {0042-465X}, pages = {5 -- 7}, year = {1997}, language = {en} } @article{WiescherKotliarNeuhannetal.2010, author = {Wiescher, A. and Kotliar, Konstantin and Neuhann, T. and Lanzl, Ines M.}, title = {Rasch progrediente Visusminderung beider Augen bei einem jungen Patienten}, series = {Der Ophthalmologe}, volume = {105}, journal = {Der Ophthalmologe}, number = {4}, publisher = {Springer}, address = {Berlin}, issn = {1433-0423}, doi = {10.1007/s00347-007-1586-x}, pages = {389 -- 392}, year = {2010}, abstract = {Ein 34-j{\"a}hriger m{\"a}nnlicher Patient stellte sich zur Abkl{\"a}rung einer seit dem 9. Lebensjahr bestehenden und im letzten Jahr rasch progredienten Visusminderung beider Augen bei uns vor. Er beschrieb eine subjektiv zunehmende, im Spiegel f{\"u}r ihn selbst sichtbare, weißliche Tr{\"u}bung in der Pupille beidseits und eine starke Blendempfindlichkeit. Nebenbefundlich gab er rezidivierende Konjunktivitiden und morgens verklebte Lider an. Eine Allergie auf Gr{\"a}serpollen und eine Unvertr{\"a}glichkeit auf Alkohol sowie mehrere Lebensmittel seien ebenfalls bekannt. Zus{\"a}tzlich leidet der Patient an stark ausgepr{\"a}gtem atopischem Ekzem. Dieses wurde nie systemisch, sondern nur bei Bedarf mit kortisonhaltiger Salbe therapiert.}, language = {de} } @article{MenzelKotliarLanzl2009, author = {Menzel, C. and Kotliar, Konstantin and Lanzl, I.}, title = {Retrospektive Untersuchung jahreszeitlich bedingter Einflussfaktoren auf den Augeninnendruck therapierter Glaukompatienten}, series = {Der Ophthalmologe}, volume = {106}, journal = {Der Ophthalmologe}, number = {11}, publisher = {-}, isbn = {1433-0423}, pages = {1006 -- 1011}, year = {2009}, language = {de} } @article{KotliarMaierBaueretal.2007, author = {Kotliar, Konstantin and Maier, Mathias and Bauer, Svetlana and Feucht, Nikolaus}, title = {Effect of intravitreal injections and volume changes on intraocular pressure: clinical results and biomechanical model / Kotliar, Konstantin ; Maier, Mathias ; Bauer, Svetlana ; Feucht, Nikolaus ; Lohmann, Chris ; Lanzl, Ines}, series = {Acta Ophthalmologica Scandinavica. 85 (2007), H. 7}, journal = {Acta Ophthalmologica Scandinavica. 85 (2007), H. 7}, publisher = {-}, isbn = {1755-3768}, pages = {777 -- 781}, year = {2007}, language = {en} } @article{NurispahicKotliarLanzl2008, author = {Nurispahic, A. and Kotliar, Konstantin and Lanzl, I.}, title = {Messung der Akkommodation mittels optischer Biometrie}, series = {Der Ophthalmologe}, volume = {105}, journal = {Der Ophthalmologe}, number = {4}, publisher = {-}, isbn = {1433-0423}, pages = {369 -- 375}, year = {2008}, language = {de} } @article{LanzlSeidovaErbenetal.2010, author = {Lanzl, Ines M. and Seidova, Seid-Fatima and Erben, A. and Th{\"u}rmel, K. and Kotliar, Konstantin}, title = {Diffuse stromale Hornhauttr{\"u}bungen und Ver{\"a}nderungen der H{\"a}nde}, series = {Der Ophthalmologe}, volume = {107}, journal = {Der Ophthalmologe}, number = {4}, publisher = {Springer}, address = {Berlin}, issn = {1433-0423}, doi = {10.1007/s00347-009-2066-2}, pages = {363 -- 365}, year = {2010}, abstract = {Bilaterale stromale Hornhauttr{\"u}bungen sind f{\"u}r den Augenarzt eine differenzialdiagnostische Herausforderung. Im folgenden Beitrag werden 2 Patieninnen (30 und 36 Jahre) mit unterschiedlich stark ausgepr{\"a}gter stromaler diffuser Hornhauttr{\"u}bung vorgestellt. Patientin 1 war kleinw{\"u}chsig (114 cm) und Patientin 2 normal groß (172 cm). Beide Patientinnen wiesen ver{\"a}nderte Gelenkstrukturen an Hand und Fußgelenken sowie diffuse stromale Hornhauttr{\"u}bungen auf. Des Weiteren lagen eine Mitral- und Aorteninsuffizienz (Patientin 1) bzw. eine Aorteninsuffizienz (Patientin 2) vor. Die stromalen diffusen Hornhauttr{\"u}bungen ließen im Zusammenhang mit den Gelenkver{\"a}nderungen ein Scheie-Syndrom vermuten. Therapeutisch ist bei Patienten mit Visusminderung eine (lamell{\"a}re) Keratoplastik sinnvoll.}, language = {de} } @article{LanzlSeidovaMaieretal.2011, author = {Lanzl, Ines M. and Seidova, Seid-Fatima and Maier, Mathias and Schmidt-Trucks{\"a}ss, Arno and Halle, Martin and Kotliar, Konstantin}, title = {Dynamic retinal vessel response to flicker in age-related macular degeneration patients before and after vascular endothelial growth factor inhibitor injection}, series = {Acta Ophthalmologica}, volume = {89}, journal = {Acta Ophthalmologica}, number = {5}, publisher = {Wiley}, address = {Weinheim}, isbn = {1755-3768}, pages = {472 -- 479}, year = {2011}, language = {en} } @article{KotliarMaierBaueretal.2008, author = {Kotliar, Konstantin and Maier, Mathias and Bauer, Svetlana and Feucht, Nikolaus and Lohmann, Chris and Lanzl, Ines}, title = {Intravitreal injection of triamcinolone acetonide and intraocular pressure: author's reply}, series = {Acta Ophthalmologica}, volume = {86}, journal = {Acta Ophthalmologica}, number = {6}, publisher = {-}, isbn = {1755-3768}, pages = {692 -- 693}, year = {2008}, language = {en} } @article{KotliarNagelVilseretal.2008, author = {Kotliar, Konstantin and Nagel, Edgar and Vilser, Walthard and Lanzl, Ines M.}, title = {Functional in vivo assessment of retinal artery microirregularities in glaucoma / Kotliar, Konstantin E. ; Nagel, Edgar ; Vilser, Walthard ; Lanzl, Ines M.}, series = {Acta Ophthalmologica. 86 (2008), H. 4}, journal = {Acta Ophthalmologica. 86 (2008), H. 4}, publisher = {-}, isbn = {1755-3768}, pages = {424 -- 433}, year = {2008}, language = {en} } @article{KotliarLanzlHanssenetal.2012, author = {Kotliar, Konstantin and Lanzl, Ines M. and Hanssen, Henner and Eberhardt, Karla and Vilser, Walthard and Halle, Martin and Heemann, Uwe and Schmidt-Trucks{\"a}ss, Arno and Baumann, Marcus}, title = {Does increased blood pressure rather than aging influence retinal pulse wave velocity?}, series = {Investigative Ophthalmology \& Visual Science, IOVS}, volume = {53}, journal = {Investigative Ophthalmology \& Visual Science, IOVS}, number = {4}, publisher = {ARVO}, address = {Rockville, Md.}, issn = {0146-0404}, doi = {10.1167/iovs.11-8815}, pages = {2119 -- 2126}, year = {2012}, abstract = {Purpose: It was demonstrated previously that retinal pulse wave velocity (rPWV) as a measure of retinal arterial stiffness is increased in aged anamnestically healthy volunteers compared with young healthy subjects. Using novel methodology of rPWV assessment this finding was confirmed and investigated whether it might relate to the increased blood pressure usually accompanying the aging process, rather than to the aging itself. Methods: A total of 12 young 25.5-year-old (24.0-28.8) [median(1st quartile-3rd quartile)] and 12 senior 68.5-year-old (63.8-71.8) anamnestically healthy volunteers; and 12 senior 63.0-year-old (60.8-65.0) validated healthy volunteers and 12 young 33.0-year-old (29.5-35.0) hypertensive patients were examined. Time-dependent alterations of vessel diameter were assessed by the Dynamic Vessel Analyzer in a retinal artery of each subject. The data were filtered and processed using mathematical signal analysis and rPWVs were calculated. Results: rPWV amounted to 1200 (990-1470) RU (relative units)/s in the hypertensive group and to 1040 (700-2230) RU/s in anamnestically healthy seniors. These differed significantly from rPWVs in young healthy group (410 [280-500] RU/s) and in validated healthy seniors (400 [320-510] RU/s). rPWV associated with age and mean arterial pressure (MAP) in the pooled cohort excluded validated healthy seniors. In a regression model these associations remain when alternately adjusted for MAP and age. When including validated healthy seniors in the pooled cohort only association with MAP remains. Conclusions: Both aging (with not excluded cardiovascular risk factors) and mild hypertension are associated with elevated rPWV. rPWV increases to a similar extent both in young mildly hypertensive subjects and in aged anamnestically healthy persons. Healthy aging is not associated with increased rPWV.}, language = {en} } @article{KotliarNagelVilseretal.2010, author = {Kotliar, Konstantin and Nagel, Edgar and Vilser, Walthard and Seidova, Seid-Fatima and Lanzl, Ines}, title = {Microstructural alterations of retinal arterial blood column along the vessel axis in systemic hypertension}, series = {Investigative Ophthalmology \& Visual Science, IOVS}, volume = {51}, journal = {Investigative Ophthalmology \& Visual Science, IOVS}, number = {4}, publisher = {ARVO}, address = {Rockville, Md.}, issn = {0146-0404}, doi = {10.1167/iovs.09-3649}, pages = {2165 -- 2172}, year = {2010}, abstract = {Purpose: Image analysis by the retinal vessel analyzer (RVA) observes retinal vessels in their dynamic state online noninvasively along a chosen vessel segment. It has been found that high-frequency diameter changes in the retinal artery blood column along the vessel increase significantly in anamnestically healthy volunteers with increasing age and in patients with glaucoma during vascular dilation. This study was undertaken to investigate whether longitudinal sections of the retinal artery blood column are altered in systemic hypertension. Methods: Retinal arteries of 15 untreated patients with essential arterial hypertension (age, 50.9 ± 11.9 years) and of 15 age-matched anamnestically healthy volunteers were examined by RVA. After baseline assessment, a monochromatic luminance flicker (530-600 nm; 12.5 Hz; 20 s) was applied to evoke retinal vasodilation. Differences in amplitude and frequency of spatial artery blood column diameter change along segments (longitudinal arterial profiles) of 1 mm in length were measured and analyzed using Fourier transformation. Results: In the control group, average reduced power spectra (ARPS) of longitudinal arterial profiles did not differ when arteries changed from constriction to dilation. In the systemic hypertension group, ARPS during constriction, baseline, and restoration were identical and differed from ARPS during dilation (P < 0.05). Longitudinal arterial profiles in both groups showed significant dissimilitude at baseline and restoration (P < 0.05). Conclusions: The retinal artery blood column demonstrates microstructural alterations in systemic hypertension and is less irregular along the vessel axis during vessel dilation. These microstructural changes may be an indication of alterations in vessel wall rigidity, vascular endothelial function, and smooth muscle cells in this disease, leading to impaired perfusion and regulation.}, language = {en} } @article{KotliarVilserSchmidtTrucksaessetal.2009, author = {Kotliar, Konstantin and Vilser, W. and Schmidt-Trucks{\"a}ss, A. and Halle, M. and Lanzl, I. M.}, title = {Zeitliche Schwingungen retinaler Gef{\"a}ßdurchmesser bei Gesunden unterschiedlichen Alters : Kreuz- und Autokorrelation f{\"u}r dynamische Gef{\"a}ßanalyse}, series = {Der Ophthalmologe}, volume = {106}, journal = {Der Ophthalmologe}, number = {7}, publisher = {-}, isbn = {1433-0423}, pages = {609 -- 618}, year = {2009}, language = {de} } @article{KotliarLanzl2011, author = {Kotliar, Konstantin and Lanzl, Ines M.}, title = {Can vascular function be assessed by the interpretation of retinal vascular diameter changes?}, series = {Investigative Ophthalmology \& Visual Science, IOVS. 52 (2011), H. 1}, journal = {Investigative Ophthalmology \& Visual Science, IOVS. 52 (2011), H. 1}, publisher = {ARVO}, address = {Rockville, Md.}, isbn = {0146-0404}, pages = {635 -- 636}, year = {2011}, language = {en} } @article{KotliarMueckeVilseretal.2008, author = {Kotliar, Konstantin and M{\"u}cke, Bruno and Vilser, Walthard and Schilling, Rudolf}, title = {Effect of aging on retinal artery blood column diameter measured along the vessel axis / Kotliar, Konstantin E. ; M{\"u}cke, Bruno ; Vilser, Walthard ; Schilling, Rudolf ; Lanzl, Ines M.}, series = {Investigative Ophthalmology \& Visual Science, IOVS. 49 (2008), H. 5}, journal = {Investigative Ophthalmology \& Visual Science, IOVS. 49 (2008), H. 5}, publisher = {-}, isbn = {0146-0404}, pages = {2094 -- 2102}, year = {2008}, language = {en} } @article{NguyenDuongTranetal.2012, author = {Nguyen, Nhu Huynh and Duong, Minh Tuan and Tran, Thanh Ngoc and Pham, Phu Tinh and Grottke, O. and Tolba, R. and Staat, Manfred}, title = {Influence of a freeze-thaw cycle on the stress-stretch curves of tissues of porcine abdominal organs}, series = {Journal of Biomechanics}, volume = {45}, journal = {Journal of Biomechanics}, number = {14}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-2380}, doi = {10.1016/j.jbiomech.2012.07.008}, pages = {2382 -- 2386}, year = {2012}, abstract = {The paper investigates both fresh porcine spleen and liver and the possible decomposition of these organs under a freeze-thaw cycle. The effect of tissue preservation condition is an important factor which should be taken into account for protracted biomechanical tests. In this work, tension tests were conducted for a large number of tissue specimens from twenty pigs divided into two groups of 10. Concretely, the first group was tested in fresh state; the other one was tested after a freeze-thaw cycle which simulates the conservation conditions before biomechanical experiments. A modified Fung model for isotropic behavior was adopted for the curve fitting of each kind of tissues. Experimental results show strong effects of the realistic freeze-thaw cycle on the capsule of elastin-rich spleen but negligible effects on the liver which virtually contains no elastin. This different behavior could be explained by the autolysis of elastin by elastolytic enzymes during the warmer period after thawing. Realistic biomechanical properties of elastin-rich organs can only be expected if really fresh tissue is tested. The observations are supported by tests of intestines.}, language = {en} } @article{NovacekTranKlingeetal.2012, author = {Novacek, V. and Tran, Thanh Ngoc and Klinge, U. and Tolba, R. H. and Staat, Manfred and Bronson, D. G. and Miesse, A. M. and Whiffen, J. and Turquier, F.}, title = {Finite element modelling of stapled colorectal end-to-end anastomosis : Advantages of variable height stapler design}, series = {Journal of Biomechanics}, volume = {45}, journal = {Journal of Biomechanics}, number = {115}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-2380}, doi = {10.1016/j.jbiomech.2012.07.021}, pages = {2693 -- 2697}, year = {2012}, abstract = {The impact of surgical staplers on tissues has been studied mostly in an empirical manner. In this paper, finite element method was used to clarify the mechanics of tissue stapling and associated phenomena. Various stapling modalities and several designs of circular staplers were investigated to evaluate the impact of the device on tissues and mechanical performance of the end-to-end colorectal anastomosis. Numerical simulations demonstrated that a single row of staples is not adequate to resist leakage due to non-linear buckling and opening of the tissue layers between two adjacent staples. Compared to the single staple row configuration, significant increase in stress experienced by the tissue at the inner staple rows was observed in two and three rows designs. On the other hand, adding second and/or third staple row had no effect on strain in the tissue inside the staples. Variable height design with higher staples in outer rows significantly reduced the stresses and strains in outer rows when compared to the same configuration with flat cartridge.}, language = {en} } @article{Huening2008, author = {H{\"u}ning, Felix}, title = {Die Anforderungen steigen : Entwicklungstrends bei MOSFETs f{\"u}r den Automobilbereich}, series = {Elektronik-Industrie. 39 (2008), H. 5}, journal = {Elektronik-Industrie. 39 (2008), H. 5}, publisher = {-}, isbn = {0174-5522}, pages = {74 -- 76}, year = {2008}, language = {de} } @article{CaroMazzonCaemmereretal.2011, author = {Caro, Abrao and Mazzon, Jos{\´e} Afonso and Caemmerer, Barbara and Weßling, Matthias}, title = {Inovatividade, envolvimento, atitude e experiencia na adocao da compra on-line - Innovation, involvement, attitude and experience in buying online}, series = {Revista de administra{\c{c}}{\~a}o de empr{\^e}sas : RAE}, volume = {51}, journal = {Revista de administra{\c{c}}{\~a}o de empr{\^e}sas : RAE}, number = {6}, publisher = {-}, address = {S{\~a}o Paulo}, issn = {0034-7590}, pages = {568 -- 584}, year = {2011}, language = {de} } @article{SpelthahnSchubertSchoening2012, author = {Spelthahn, Heiko and Schubert, J{\"u}rgen and Sch{\"o}ning, Michael Josef}, title = {D{\"u}nnschichtsensoren f{\"u}r die Schwermetallanalytik}, series = {GIT : Labor-Fachzeitschrift}, volume = {56}, journal = {GIT : Labor-Fachzeitschrift}, number = {4}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {0016-3538}, pages = {285 -- 287}, year = {2012}, abstract = {Die Detektion von Schadstoffen repr{\"a}sentiert in der Umweltanalytik eine wichtige Aufgabenstellung. Gerade die Abwasser- bzw. Brauchwasseranalytik sowie die Prozesskontrolle haben einen hohen Stellenwert. Siliziumbasierte D{\"u}nnschichtsensoren bieten eine kosteng{\"u}nstige M{\"o}glichkeit, „online"-Messungen bzw. Vor-Ort-Messungen zeitnah durchzuf{\"u}hren. In dieser Arbeit wird ein potentiometrisches Sensorarray auf der Basis von Chalkogenidgl{\"a}sern zur Detektion von Schwermetallen in w{\"a}ssrigen Medien vorgestellt.}, language = {en} } @article{Huening2009, author = {H{\"u}ning, Felix}, title = {Hart im Nehmen : Low-Voltage-Powermosfets mit Super-Junction-1-Technologie optimieren}, series = {Elektronik-Journal. 44 (2009), H. 12}, journal = {Elektronik-Journal. 44 (2009), H. 12}, publisher = {-}, isbn = {0013-5674}, pages = {36 -- 38}, year = {2009}, language = {de} } @article{Huening2012, author = {H{\"u}ning, Felix}, title = {Using Trench PowerMOSFETs in Linear Mode}, series = {Power Electronics Europe (2012)}, journal = {Power Electronics Europe (2012)}, publisher = {DFA Media}, address = {Tonbridge}, issn = {1748-3530}, pages = {27 -- 29}, year = {2012}, abstract = {If we think about applications for modern Power MOSFETs using trench technology, running them in linear mode may not be top of the priority list. Yet there are multiple uses for Trench Power MOSFETs in linear mode. In fact, even turning the device on and off in switching applications is a form of linear operation. Also, these components can be run in linear mode to protect the device against voltage surges. This article will illustrate the factors that need to be considered for linear operation and show how Trench Power MOSFETs are suited to it.}, language = {en} } @article{Huening2011, author = {H{\"u}ning, Felix}, title = {PowerMOSFETs in ANL2-Technologie : Ansteuerungen bis in den kW-Bereich mit wenig Verlustleistung und Platzbedarf}, series = {Elektronik-Industrie}, volume = {42}, journal = {Elektronik-Industrie}, number = {10}, publisher = {H{\"u}thig}, address = {Heidelberg}, issn = {0174-5522}, pages = {36 -- 39}, year = {2011}, language = {de} } @article{Huening2009, author = {H{\"u}ning, Felix}, title = {Mosfet ottimizzati per l'automotive}, series = {Selezione di Elettronica (2009)}, journal = {Selezione di Elettronica (2009)}, publisher = {-}, pages = {115 -- 117}, year = {2009}, language = {de} } @article{Huening2008, author = {H{\"u}ning, Felix}, title = {Entwicklungstrends bei MOSFETs f{\"u}r den Automobilbereich}, series = {Elektronik-Industrie . 39 (2008), H. 5}, journal = {Elektronik-Industrie . 39 (2008), H. 5}, publisher = {-}, isbn = {0174-5522}, pages = {74 -- 76}, year = {2008}, language = {en} } @article{Huening2009, author = {H{\"u}ning, Felix}, title = {SMD packages for PowerMOSFETs in automotive applications - developments and trends}, series = {Automotive Designline Europe (2009)}, journal = {Automotive Designline Europe (2009)}, publisher = {-}, year = {2009}, language = {en} } @article{HueningEifertHandricketal.2006, author = {H{\"u}ning, Felix and Eifert, T. and Handrick, K. and Neuhausen, U.}, title = {Computational Magnetochemistry: Complementary Quantum Mechanical Tools / Eifert, T. ; Handrick, K. ; H{\"u}ning, F. ; Neuhausen, U. ; Schilder, H. ; Lueken, H.}, series = {20 Jahre Wilhelm-Klemm-Stiftung / Kuratorium der Wilhelm-Klemm-Stiftung (Hrsg.)}, journal = {20 Jahre Wilhelm-Klemm-Stiftung / Kuratorium der Wilhelm-Klemm-Stiftung (Hrsg.)}, publisher = {Shaker}, address = {Aachen}, isbn = {978-3-8322-5520-6}, pages = {193ff}, year = {2006}, language = {en} } @article{Huening2008, author = {H{\"u}ning, Felix}, title = {Robusti affidabili per le Sfide dell'automotive}, series = {Selezione di Elettronica (2008)}, journal = {Selezione di Elettronica (2008)}, publisher = {-}, pages = {116 -- 117}, year = {2008}, language = {de} } @article{HueningLukenSchilderetal.2001, author = {H{\"u}ning, Felix and Luken, Heiko and Schilder, Herbert and Eifert, Thomas}, title = {Magnetochemistry: Compounds and Concepts / Lueken, Heiko ; Schilder, Herbert ; Eifert, Thomas ; Handrick, Klaus ; H{\"u}ning, Felix}, series = {Advances in Solid State Physics. 201 (2001)}, journal = {Advances in Solid State Physics. 201 (2001)}, publisher = {-}, pages = {515 -- 532}, year = {2001}, language = {en} } @article{HueningEifertLuekenetal.2002, author = {H{\"u}ning, Felix and Eifert, T. and Lueken, H. and Schmidt, P.}, title = {High-temperature series expansion of the magnetic susceptibility of extended magnetic systems in a complete computer implementation / Eifert, T. ; H{\"u}ning, F. ; Lueken, H. ; Schmidt, P. ; Thiele, G.}, series = {Chemical Physics Letters. 364 (2002), H. 1-2}, journal = {Chemical Physics Letters. 364 (2002), H. 1-2}, publisher = {-}, isbn = {0009-2614}, pages = {69 -- 74}, year = {2002}, language = {en} } @article{HueningEifertHandricketal.2006, author = {H{\"u}ning, Felix and Eifert, T. and Handrick, K. and Neuhausen, U.}, title = {Computational Magnetochemistry: Complementary Quantum Mechanical Tools / Eifert, T. ; Handrick, K. ; H{\"u}ning, F. ; Neuhausen, U. ; Schilder, H. ; Lueken, H.}, series = {Zeitschrift f{\"u}r Anorganische und Allgemeine Chemie (ZAAC) - Journal of Inorganic and General Chemistry . 632 (2006), H. 4}, journal = {Zeitschrift f{\"u}r Anorganische und Allgemeine Chemie (ZAAC) - Journal of Inorganic and General Chemistry . 632 (2006), H. 4}, publisher = {-}, isbn = {1521-3749}, pages = {521 -- 529}, year = {2006}, language = {en} } @article{HueningLeineweberJacobsetal.2001, author = {H{\"u}ning, Felix and Leineweber, A. and Jacobs, H. and Lueken, H.}, title = {Nitrogen Ordering and ferromagnetic properties of -Fe3N1+x (0.10  x  0.39) and -Fe3(N0.80C0.20)1.38 / Leineweber, A. ; Jacobs, H. ; H{\"u}ning, F. ; Lueken, H. ; Kockelmann, W.}, series = {Journal of Alloys and Compounds. 316 (2001), H. 1-2}, journal = {Journal of Alloys and Compounds. 316 (2001), H. 1-2}, publisher = {-}, isbn = {1873-4669}, pages = {21 -- 38}, year = {2001}, language = {en} } @article{HueningSpartaRedhammeretal.2001, author = {H{\"u}ning, Felix and Sparta, K. and Redhammer, G. J. and Roussel, P.}, title = {Structural Phase Transition in the 2D Spin Dimer Compound SrCu2(BO3)2 / Sparta, K. ; Redhammer, G. J. ; Roussel, P. ; Heger, G. ; Roth, G. ; Ionescu, A. Lemmens, P. ; Grove, M. ; G{\"u}ntherrodt, G. ; H{\"u}ning, F. ; Lueken, H. ; Kageyama, H. ; Onizuka, K ; Ueda}, series = {The European Physical Journal B - Condensed Matter and Complex Systems. 19 (2001), H. 4}, journal = {The European Physical Journal B - Condensed Matter and Complex Systems. 19 (2001), H. 4}, publisher = {-}, isbn = {1434-6036}, pages = {507 -- 516}, year = {2001}, language = {en} } @article{HillenAlperSelverFischeretal.2007, author = {Hillen, Walter and Alper Selver, M. and Fischer, Felix and Kuntalp, Mehmet}, title = {A software tool for interactive generation, representation, and systematical storage of transfer functions for 3D medical images / Alper Selver, M. ; Fischer, Felix ; Kuntalp, Mehmet ; Hillen, Walter}, series = {Computer Methods and Programs in Biomedicine. 86 (2007), H. 3}, journal = {Computer Methods and Programs in Biomedicine. 86 (2007), H. 3}, publisher = {-}, isbn = {0169-2607}, pages = {270 -- 280}, year = {2007}, language = {en} } @article{HueningWilkeNakielskietal.1997, author = {H{\"u}ning, Felix and Wilke, I. and Nakielski, G. and Kotzler, J.}, title = {Dynamic conductivity of YBCO thin films from low to very high frequencies / Wilke, I. ; Nakielski, G. ; Kotzler, J. ; Subke, K. O. ; Jaekel, C. ; H{\"u}ning, F. ; Roskos, H. G. ; Kurz, Heinrich}, series = {Applied superconductivity 1997 : proceedings of EUCAS 1997, the Third European Conference on Applied Superconductivity, held in the Netherlands, 30 June - 3 July 1997 / ed. by H. Rogalla}, journal = {Applied superconductivity 1997 : proceedings of EUCAS 1997, the Third European Conference on Applied Superconductivity, held in the Netherlands, 30 June - 3 July 1997 / ed. by H. Rogalla}, publisher = {IOP}, address = {Bristol}, isbn = {0-7503-0487-1}, pages = {121 -- 124}, year = {1997}, language = {en} } @article{HueningLeineweberJacobsetal.1999, author = {H{\"u}ning, Felix and Leineweber, A. and Jacobs, H. and Lueken, H.}, title = {ε-Fe3N: magnetic structure, magnetization and temperature dependent disorder of nitrogen / Leineweber, A. ; Jacobs, H. ; H{\"u}ning, F. ; Lueken, H. ; Schilder, H. ; Kockelmann, W.}, series = {Journal of Alloys and Compounds. 288 (1999), H. 1-2}, volume = {288}, journal = {Journal of Alloys and Compounds. 288 (1999), H. 1-2}, number = {1-2}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {1873-4669}, pages = {79 -- 87}, year = {1999}, abstract = {ε-Fe3N has been investigated by time-of-flight neutron diffraction (temperature range 4.2-618 K) and SQUID magnetometry (2-700 K, B≤5 T). A ferromagnetic spin structure is observed with magnetic moments oriented perpendicular to the c-axis of the hexagonal nuclear structure. The magnetic saturation moment of iron is 2.2 μB at 4.2 K from neutron diffraction and 2.0 μB from magnetic measurements and decreases in a Brillouin-like manner on heating to TC=575 K. Above 450 K an increasing but reversible disorder of the nitrogen partial structure is observed.}, language = {en} } @article{KlingeWilkeMuehl2012, author = {Klinge, Uwe and Wilke, Ralf and M{\"u}hl, Thomas}, title = {Auswahl der Herniennetze nach der "effektiven Porosit{\"a}t" - warum das Gewicht weniger wichtig ist}, series = {Chirurgische Allgemeine : CHAZ ; Zeitung f{\"u}r Klinik und Praxis}, volume = {13}, journal = {Chirurgische Allgemeine : CHAZ ; Zeitung f{\"u}r Klinik und Praxis}, number = {12}, publisher = {Kaden}, address = {Mannheim}, isbn = {1615-5378}, pages = {297 -- 301}, year = {2012}, language = {de} } @article{BohrnStuetzFuchsetal.2012, author = {Bohrn, U. and St{\"u}tz, E. and Fuchs, K. and Fleischer, M. and Sch{\"o}ning, Michael Josef and Wagner, P.}, title = {Monitoring of irritant gas using a whole-cell-based sensor system}, series = {Sensors and Actuators B: Chemical}, volume = {175}, journal = {Sensors and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2012.05.088}, pages = {208 -- 217}, year = {2012}, abstract = {Cell-based sensors for the detection of gases have long been underrepresented, due to the cellular requirement of being cultured in a liquid environment. In this work we established a cell-based gas biosensor for the detection of toxic substances in air, by adapting a commercial sensor chip (Bionas®), previously used for the measurement of pollutants in liquids. Cells of the respiratory tract (A549, RPMI 2650, V79), which survive at a gas phase in a natural context, are used as biological receptors. The physiological cell parameters acidification, respiration and morphology are continuously monitored in parallel. Ammonia was used as a highly water-soluble model gas to test the feasibility of the sensor system. Infrared measurements confirmed the sufficiency of the medium draining method. This sensor system provides a basis for many sensor applications such as environmental monitoring, building technology and public security.}, language = {en} } @article{SchneiderSchneider2012, author = {Schneider, Bettina and Schneider, Wilhelm}, title = {Due Diligence - Grundlagen und Checkliste f{\"u}r KMU}, series = {Betriebswirtschaft im Blickpunkt}, journal = {Betriebswirtschaft im Blickpunkt}, publisher = {IWW Institut f{\"u}r Wissen in der Wirtschaft}, address = {Nordkirchen}, issn = {2191-1118}, pages = {148 -- 149}, year = {2012}, abstract = {Im Folgenden sollen Anlass und Inhalt einer Due Diligence erl{\"a}utert werden. Im Rahmen einer Checkliste werden Beratern und Unternehmen Hinweise zu m{\"o}glichen Pr{\"u}fungsgebieten sowie zu vorzuhaltenden oder zu pr{\"u}fenden Unterlagen gegeben. Entstanden ist die Checkliste aus der langj{\"a}hrigen praktischen T{\"a}tigkeit der Autoren bei einer großen Wirtschaftspr{\"u}fungsgesellschaft bzw. einer deutschen Großbank.}, language = {de} } @article{BleckenHolthausSellheier2012, author = {Blecken, Udo and Holthaus-Sellheier, Ursula}, title = {Quantitative Prognoseverfahren f{\"u}r Mietpreise von Bueroimmobilien am Beispiel D{\"u}sseldorf}, series = {GuG : Grundst{\"u}cksmarkt und Grundst{\"u}ckswert}, volume = {23}, journal = {GuG : Grundst{\"u}cksmarkt und Grundst{\"u}ckswert}, number = {1}, publisher = {Werner}, address = {K{\"o}ln}, issn = {0938-0175}, pages = {12 -- 21}, year = {2012}, language = {de} } @article{KurulganDemirciDemirciLinderetal.2012, author = {Kurulgan Demirci, Eylem and Demirci, Taylan and Linder, Peter and Trzewik, J{\"u}rgen and Gierkowski, Jessica Ricarda and Gossmann, Matthias and Kayser, Peter and Porst, Dariusz and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l}, title = {rhAPC reduces the endothelial cell permeability via a decrease of contractile tensions induced by endothelial cells}, series = {Journal of Bioscience and Bioengineering}, volume = {113}, journal = {Journal of Bioscience and Bioengineering}, number = {2}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1347-4421}, doi = {10.1016/j.jbiosc.2012.03.019}, pages = {212 -- 219}, year = {2012}, abstract = {All cells generate contractile tension. This strain is crucial for mechanically controlling the cell shape, function and survival. In this study, the CellDrum technology quantifying cell's (the cellular) mechanical tension on a pico-scale was used to investigate the effect of lipopolysaccharide (LPS) on human aortic endothelial cell (HAoEC) tension. The LPS effect during gram-negative sepsis on endothelial cells is cell contraction causing endothelium permeability increase. The aim was to finding out whether recombinant activated protein C (rhAPC) would reverse the endothelial cell response in an in-vitro sepsis model. In this study, the established in-vitro sepsis model was confirmed by interleukin 6 (IL-6) levels at the proteomic and genomic levels by ELISA, real time-PCR and reactive oxygen species (ROS) activation by florescence staining. The thrombin cellular contraction effect on endothelial cells was used as a positive control when the CellDrum technology was applied. Additionally, the Ras homolog gene family, member A (RhoA) mRNA expression level was checked by real time-PCR to support contractile tension results. According to contractile tension results, the mechanical predominance of actin stress fibers was a reason of the increased endothelial contractile tension leading to enhanced endothelium contractility and thus permeability enhancement. The originality of this data supports firstly the basic measurement principles of the CellDrum technology and secondly that rhAPC has a beneficial effect on sepsis influenced cellular tension. The technology presented here is promising for future high-throughput cellular tension analysis that will help identify pathological contractile tension responses of cells and prove further cell in-vitro models.}, language = {en} } @article{HueningJaekelFrancoisetal.1996, author = {H{\"u}ning, Felix and Jaekel, C. and Francois, I. and Kyas, G.}, title = {Microwave surface impedance measurements on high-Tc superconductors / Jaekel, C. ; Francois, I. ; Kyas, G. ; H{\"u}ning, F. ; Roskos, H. G. ; Borghs, G. ; Kurz, H.}, series = {Czechoslovak Journal of Physics. 46 (1996), H. Suppl. 2}, journal = {Czechoslovak Journal of Physics. 46 (1996), H. Suppl. 2}, number = {46}, publisher = {Springer Science+Business Media}, address = {Dordrecht}, isbn = {1572-9486}, pages = {1117 -- 1118}, year = {1996}, language = {en} } @article{Hirschberg2008, author = {Hirschberg, Rainer}, title = {Decentral pumps in heating systems - a new hydraulic approac}, series = {1st International Rotating Equipment Conference - Pumps and Compressors, 9th Pump Users International Forum, 9. Internationales Pumpenanwenderforum, Final Report, D{\"u}sseldorf, DE, 28.-29. Oct, 2008}, journal = {1st International Rotating Equipment Conference - Pumps and Compressors, 9th Pump Users International Forum, 9. Internationales Pumpenanwenderforum, Final Report, D{\"u}sseldorf, DE, 28.-29. Oct, 2008}, publisher = {-}, pages = {1 -- 10}, year = {2008}, language = {en} } @article{Hirschberg2007, author = {Hirschberg, Rainer}, title = {Wirtschaftlichkeit geb{\"a}udetechnischer Anlagen VDI 2067 - Berechnung des instation{\"a}ren thermischen Verhaltens von R{\"a}umen und Geb{\"a}uden nach VDI 6007}, series = {Umsetzung der EU-Richtlinie (EPBD), Gesamtenergieeffizienz von Geb{\"a}uden - wie gehen wir damit um?, VDI-Gesellschaft Technische Geb{\"a}udeausr{\"u}stung (VDI-TGA), Dortmund, DE, 30.-31. Jan, 2007}, journal = {Umsetzung der EU-Richtlinie (EPBD), Gesamtenergieeffizienz von Geb{\"a}uden - wie gehen wir damit um?, VDI-Gesellschaft Technische Geb{\"a}udeausr{\"u}stung (VDI-TGA), Dortmund, DE, 30.-31. Jan, 2007}, publisher = {VDI-Verl.}, address = {D{\"u}sseldorf}, isbn = {978-3-18-091952-2}, pages = {188 S. Ill., graph. Darst.}, year = {2007}, language = {de} } @article{EngelsKrauskopf2011, author = {Engels, Elmar and Krauskopf, S.}, title = {Innovation in Motion-Logic programming - a versatile interface}, series = {Proceedings to the 12th International Workshop on Research and Education in Mechatronics, REM 2011, Kocaeli, Turkey, 15.09.-16.09.2011}, journal = {Proceedings to the 12th International Workshop on Research and Education in Mechatronics, REM 2011, Kocaeli, Turkey, 15.09.-16.09.2011}, publisher = {-}, isbn = {978-975-8047-96-3}, year = {2011}, language = {en} } @article{SpelthahnKirsanovLeginetal.2012, author = {Spelthahn, Heiko and Kirsanov, Dmitry and Legin, Andrey and Osterrath, Thomas and Schubert, J{\"u}rgen and Zander, Willi and Sch{\"o}ning, Michael Josef}, title = {Development of a thin-film sensor array for analytical monitoring of heavy metals in aqueous solutions}, series = {Physica Status Solidi (a)}, volume = {209}, journal = {Physica Status Solidi (a)}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, isbn = {1862-6319}, doi = {10.1002/pssa.201100733}, pages = {885 -- 891}, year = {2012}, abstract = {In industrial processes there is a variety of heavy metals (e.g., copper, zinc, cadmium, and lead) in use for wires, coatings, paints, alloys, batteries, etc. Since the application of these transition metals for industry is inevitable, it is a vital task to develop proper analytical techniques for their monitoring at low activity levels, especially because most of these elements are acutely toxic for biological organisms. The determination of ions in solution by means of a simple and inexpensive sensor array is, therefore, a promising task. In this work, a sensor array with heavy metal-sensitive chalcogenide glass membranes for the simultaneous detection of the four ions Ag⁺, Cu2⁺, Cd2⁺, and Pb2⁺ in solution is realized. The results of the physical characterization by means of microscopy, profilometry, Rutherford backscattering spectroscopy (RBS), and scanning electron microscopy (SEM) as well as the electrochemical characterization by means of potentiometric measurements are presented. Additionally, the possibility to expand the sensor array by polymeric sensor membranes is discussed.}, language = {en} } @article{SchneiderSchneider2012, author = {Schneider, Bettina and Schneider, Wilhelm}, title = {Jahresabschluss nach BilMoG : Ansatz-, Ausweis- und Bewertungsvorschriften}, series = {Das Wirtschaftsstudium : wisu ; Zeitschrift f{\"u}r Ausbildung, Examen, Berufseinstieg und Fortbildung}, volume = {41}, journal = {Das Wirtschaftsstudium : wisu ; Zeitschrift f{\"u}r Ausbildung, Examen, Berufseinstieg und Fortbildung}, number = {4}, publisher = {Lange}, address = {D{\"u}sseldorf}, issn = {0340-3084}, pages = {529 -- 535}, year = {2012}, language = {de} } @article{HavermannBeylich1998, author = {Havermann, Marc and Beylich, A. E.}, title = {Combined Measurement of Velocity, Temperature and Pressure in Compressible Gas Flows Using Laser-Induced Iodine Fluorescence / Havermann, M. ; Beylich, A. E.}, publisher = {-}, year = {1998}, language = {en} } @article{HavermannSeilerGeorgeetal.2002, author = {Havermann, Marc and Seiler, F. and George, A. and Leopold, F.}, title = {Enhanced Doppler Picture Velocimetry (DPV) for Planar Velocity Measurements in High-Speed Shock Tunnel Flow / Seiler, F. ; George, A. ; Leopold, F. ; Havermann, M. ; Srulijes, J.}, series = {10th International Symposium on Flow Visualization : Kyōto, Japan, August 26 - 29, 2002 / sponsored by International Flow Visualization Society . [Chairman:] Toshio Kobayashi}, journal = {10th International Symposium on Flow Visualization : Kyōto, Japan, August 26 - 29, 2002 / sponsored by International Flow Visualization Society . [Chairman:] Toshio Kobayashi}, publisher = {Visualization Society of Japan}, address = {Kyoto}, isbn = {4906497829}, year = {2002}, language = {en} } @article{FoltzSchneiderWolfetal.2008, author = {Foltz, Christian and Schneider, Nicole and Wolf, Martin R. and Kausch, Bernhard and Schlick, Christopher and Luczak, Holger}, title = {Usability engineering}, series = {Collaborative and distributed chemical engineering : from understanding to substantial design process support; results of the IMPROVE Project. - (Lecture notes in computer science ; 4970)}, journal = {Collaborative and distributed chemical engineering : from understanding to substantial design process support; results of the IMPROVE Project. - (Lecture notes in computer science ; 4970)}, editor = {Nagl, Manfred}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-70552-9}, doi = {10.1007/978-3-540-70552-9_21}, pages = {527 -- 554}, year = {2008}, language = {en} } @article{KirchnerReisertPuetzetal.2012, author = {Kirchner, Patrick and Reisert, Steffen and P{\"u}tz, Patrick and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Characterisation of polymeric materials as passivation layer for calorimetric H2O2 gas sensors}, series = {Physica Status Solidi (a)}, volume = {209}, journal = {Physica Status Solidi (a)}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201100773}, pages = {859 -- 863}, year = {2012}, abstract = {Calorimetric gas sensors for monitoring the H₂O₂ concentration at elevated temperatures in industrial sterilisation processes have been presented in previous works. These sensors are built up in form of a differential set-up of a catalytically active and passive temperature-sensitive structure. Although, various types of catalytically active dispersions have been studied, the passivation layer has to be established and therefore, chemically as well as physically characterised. In the present work, fluorinated ethylene propylene (FEP), perfluoralkoxy (PFA) and epoxy-based SU-8 photoresist as temperature-stable polymeric materials have been investigated for sensor passivation in terms of their chemical inertness against H₂O₂, their hygroscopic properties as well as their morphology. The polymeric materials were deposited via spin-coating on the temperature-sensitive structure, wherein spin-coated FEP and PFA show slight agglomerates. However, they possess a low absorption of humidity due to their hydrophobic surface, whereas the SU-8 layer has a closed surface but shows a slightly higher absorption of water. All of them were inert against gaseous H₂O₂ during the characterisation in H₂O₂ atmosphere that demonstrates their suitability as passivation layer for calorimetric H₂O₂ gas sensors.}, language = {en} } @article{HavermannSalveTinetal.1994, author = {Havermann, Marc and Salve, M. de and Tin, G. del and Panella, B.}, title = {Experimental Study of the Temperature Field along a Density Lock / Salve, M. de ; Tin, G. del ; Panella, B. ; Sansoldo, D. ; Havermann, M.}, series = {Proceedings : International Conference on New Trends in Nuclear System Thermohydraulics, May 30th - June 2nd, 1994, Pisa / organized by Dipartimento di Costruzioni Meccaniche e Nucleari ... . Ed. by Francesco Oriolo}, journal = {Proceedings : International Conference on New Trends in Nuclear System Thermohydraulics, May 30th - June 2nd, 1994, Pisa / organized by Dipartimento di Costruzioni Meccaniche e Nucleari ... . Ed. by Francesco Oriolo}, publisher = {-}, address = {Pisa}, pages = {623 -- 630}, year = {1994}, language = {en} } @article{HanssenNickelDrexeletal.2011, author = {Hanssen, H. and Nickel, T. and Drexel, V. and Hertel, G. and Emslander, I. and Sisic, Z. and Lorang, D. and Schuster, T. and Kotliar, Konstantin and Pressler, A. and Schmidt-Trucks{\"a}ss, A. and Weis, M. and Halle, M.}, title = {Exercise-induced alterations of retinal vessel diameters and cardiovascular risk reduction in obesity}, series = {Atherosclerosis}, volume = {216}, journal = {Atherosclerosis}, number = {2}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0021-9150}, pages = {433 -- 439}, year = {2011}, language = {en} } @article{WernerGroebelKrumbeetal.2012, author = {Werner, Frederik and Groebel, Simone and Krumbe, Christoph and Wagner, Torsten and Selmer, Thorsten and Yoshinobu, Tatsuo and Baumann, Marcus and Sch{\"o}ning, Michael Josef}, title = {Nutrient concentration-sensitive microorganism-based biosensor}, series = {Physica Status Solidi (a)}, volume = {209}, journal = {Physica Status Solidi (a)}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201100801}, pages = {900 -- 904}, year = {2012}, language = {en} } @article{Wolf2003, author = {Wolf, Martin R.}, title = {Risiko- und Maßnahmenmanagement bei der Computervalidierung}, series = {Pharma-Technologie-Journal (2003)}, journal = {Pharma-Technologie-Journal (2003)}, publisher = {-}, isbn = {0931-9700}, pages = {50 -- 62}, year = {2003}, language = {de} }