@article{MennickenPeterKaulenetal.2019,
  author    = {Mennicken, Max and Peter, Sophia Katharina and Kaulen, Corinna and Simon, Ulrich and Karth{\"a}user, Silvia},
  title     = {Controlling the Electronic Contact at the Terpyridine/Metal Interface},
  series = {The Journal of Physical Chemistry C},
  volume    = {123},
  journal   = {The Journal of Physical Chemistry C},
  number    = {35},
  issn      = {1932-7455},
  doi       = {10.1021/acs.jpcc.9b05865},
  pages     = {21367 -- 21375},
  year      = {2019},
  language  = {en}
}
@article{SavitskayaKistaubayevaIgnatovaetal.2019,
  author    = {Savitskaya, I.S. and Kistaubayeva, A.S. and Ignatova, L.V. and Digel, Ilya},
  title     = {Antimicrobial and wound healing properties of a bacterial cellulose based material containing B. subtilis cells},
  series = {Heliyon},
  volume    = {5},
  journal   = {Heliyon},
  number    = {10},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2405-8440},
  doi       = {10.1016/j.heliyon.2019.e02592},
  pages     = {Artikelnummer e02592},
  year      = {2019},
  language  = {en}
}
@article{LinderBecklerDoerretal.2019,
  author    = {Linder, Peter and Beckler, Matthias and Doerr, Leo and Stoelzle-Feix, Sonja and Fertig, Niels and Jung, Alexander and Staat, Manfred and Gossmann, Matthias},
  title     = {A new in vitro tool to investigate cardiac contractility under physiological mechanical conditions},
  series = {Journal of Pharmacological and Toxicological Methods},
  volume    = {99},
  journal   = {Journal of Pharmacological and Toxicological Methods},
  number    = {Article number 106595},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1056-8719},
  doi       = {10.1016/j.vascn.2019.05.162},
  year      = {2019},
  language  = {en}
}
@article{SchierenKleinschmidtSchmutzetal.2019,
  author    = {Schieren, Mark and Kleinschmidt, Joris and Schmutz, Axel and Loop, Torsten and Gatzweiler, Karl-Heinz and Staat, Manfred and Wappler, Frank and Defosse, Jerome},
  title     = {Comparison of forces acting on maxillary incisors during tracheal intubation with different laryngoscopy techniques: a blinded manikin study},
  series = {Anaesthesia},
  volume    = {74},
  journal   = {Anaesthesia},
  number    = {12},
  publisher = {Wiley-Blackwell},
  address   = {Oxford},
  isbn      = {1365-2044},
  doi       = {10.1111/anae.14815},
  year      = {2019},
  language  = {en}
}
@phdthesis{Bhattarai2018,
  author    = {Bhattarai, Aroj},
  title     = {Constitutive modeling of female pelvic floor dysfunctions and reconstructive surgeries using prosthetic mesh implants},
  isbn      = {978-3-9818074-8-6},
  doi       = {10.17185/duepublico/70340},
  pages     = {192 S.},
  year      = {2018},
  language  = {en}
}
@inproceedings{KromeSander2018,
  author    = {Krome, Cornelia and Sander, Volker},
  title     = {Time series analysis with apache spark and its applications to energy informatics},
  series = {Proceedings of the 7th DACH+ Conference on Energy Informatics},
  booktitle = {Proceedings of the 7th DACH+ Conference on Energy Informatics},
  doi       = {10.1186/s42162-018-0043-1},
  year      = {2018},
  abstract  = {In energy economy forecasts of different time series are rudimentary. In this study, a prediction for the German day-ahead spot market is created with Apache Spark and R. It is just an example for many different applications in virtual power plant environments. Other examples of use as intraday price processes, load processes of machines or electric vehicles, real time energy loads of photovoltaic systems and many more time series need to be analysed and predicted. This work gives a short introduction into the project where this study is settled. It describes the time series methods that are used in energy industry for forecasts shortly. As programming technique Apache Spark, which is a strong cluster computing technology, is utilised. Today, single time series can be predicted. The focus of this work is on developing a method to parallel forecasting, to process multiple time series simultaneously with R and Apache Spark.},
  language  = {en}
}
@phdthesis{Trzewik2007,
  author    = {Trzewik, J{\"u}rgen},
  title     = {Experimental analysis of biaxial mechanical tension in cell monolayers and cultured three-dimensional tissues: the celldrum technology},
  publisher = {Univerist{\"a}tsverlg Ilmenau},
  address   = {Ilmenau},
  year      = {2007},
  language  = {en}
}
@phdthesis{KurulganDemirci2012,
  author    = {Kurulgan Demirci, Eylem},
  title     = {The effect of rhAPC on contractile tension : an in-vitro sepsis model of cardiomyocytes and endothelial cells},
  year      = {2012},
  language  = {en}
}
@phdthesis{Behbahani2011,
  author    = {Behbahani, Mehdi},
  title     = {Modeling and Simulation of Shear-Dependent Platelet Reactions in Blood Vessels and Blood-Contacting Medical Devices},
  publisher = {Verlag Dr. Hut},
  address   = {M{\"u}nchen},
  isbn      = {978-3-8439-0134-5},
  year      = {2011},
  language  = {en}
}
@phdthesis{Oflaz2012,
  author    = {Oflaz, Hakan},
  title     = {Entwicklung eines Prototypen zur Prognose von Fr{\"u}hgeburten : ein biomedizintechnischer Ansatz},
  publisher = {Deutsche Zentralbibliothek f{\"u}r Medizin},
  address   = {K{\"o}ln},
  doi       = {10.4126/38m-004639208},
  year      = {2012},
  language  = {en}
}
@phdthesis{Seifarth2015,
  author    = {Seifarth, Volker},
  title     = {Ureteral tissue engineering : development of a bioreactor system and subsequent characterization of the generated biohybrids},
  publisher = {Universit{\"a}tsbibliothek Duisburg-Essen},
  address   = {Duisburg ; Essen},
  year      = {2015},
  language  = {en}
}
@article{KromeHoeftSander2019,
  author    = {Krome, Cornelia and H{\"o}ft, Jan and Sander, Volker},
  title     = {Clustering time series applied to energy markets},
  series = {Energy Informatics},
  volume    = {2},
  journal   = {Energy Informatics},
  number    = {Article numer 17},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {2520-8942},
  doi       = {10.1186/s42162-019-0076-0},
  pages     = {1 -- 20},
  year      = {2019},
  language  = {en}
}
@misc{WandreyBiselliSchroederetal.1999,
  author    = {Wandrey, Christian and Biselli, Manfred and Schr{\"o}der, Bernd and Schmoll, Hans-Joachim},
  title     = {Culturing cells on macroporous glass carriers coated with gelatin, extracellular matrix protein and stromal cells},
  pages     = {1 -- 12},
  year      = {1999},
  language  = {en}
}
@article{BhattaraiStaat2019,
  author    = {Bhattarai, Aroj and Staat, Manfred},
  title     = {A computational study of organ relocation after laparoscopic pectopexy to repair posthysterectomy vaginal vault prolapse},
  series = {Computer Methods in Biomechanics and Biomedical Engineering: Imaging \& Visualization},
  journal   = {Computer Methods in Biomechanics and Biomedical Engineering: Imaging \& Visualization},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {2168-1171},
  doi       = {10.1080/21681163.2019.1670095},
  year      = {2019},
  language  = {en}
}
@book{StaatHeitzer2003,
  author    = {Staat, Manfred and Heitzer, Michael},
  title     = {Numerical methods for limit and shakedown analysis. Deterministic and probabilistic problems.},
  publisher = {John von Neumann Institute for Computing (NIC)},
  address   = {J{\"u}lich},
  isbn      = {3-00-010001-6},
  pages     = {2, xiii, 282 Seiten},
  year      = {2003},
  language  = {en}
}
@phdthesis{Tran2008,
  author    = {Tran, Thanh Ngoc},
  title     = {Limit and shakedown analysis of plates and shells including uncertainties},
  year      = {2008},
  language  = {en}
}
@phdthesis{Pham2011,
  author    = {Pham, Phu Tinh},
  title     = {Upper bound limit and shakedown analysis of elastic-plastic bounded linearly kinematic hardening structures},
  publisher = {RWTH Aachen University},
  address   = {Aachen},
  pages     = {140 S.},
  year      = {2011},
  language  = {en}
}
@phdthesis{Duong2015,
  author    = {Duong, Minh Tuan},
  title     = {Hyperelastic modeling and soft-tissue growth integrated with the smoothed finite element method - SFEM},
  publisher = {RWTH Aachen University},
  pages     = {174 S.},
  year      = {2015},
  language  = {en}
}
@phdthesis{Tran2019,
  author    = {Tran, Ngoc Trinh},
  title     = {Limit and Shakedown analysis of structures under stochastic conditions},
  publisher = {Technische Universit{\"a}t Braunschweig},
  address   = {Braunschweig},
  doi       = {10.24355/dbbs.084-201902121135-0},
  pages     = {166 S.},
  year      = {2019},
  language  = {en}
}
@article{LeschingerBeschAydinetal.2019,
  author    = {Leschinger, Tim and Besch, Katharina and Aydin, Cansu and Staat, Manfred and Scaal, Martin and M{\"u}ller, Lars Peter and Wegmann, Kilian},
  title     = {Irreparable rotator cuff tears: a biomechanical comparison of superior capsuloligamentous complex reconstruction techniques and an interposition graft technique},
  series = {The Orthopaedic Journal of Sports Medicine},
  volume    = {7},
  journal   = {The Orthopaedic Journal of Sports Medicine},
  number    = {8},
  doi       = {10.1177/2325967119864590},
  pages     = {1 -- 5},
  year      = {2019},
  language  = {en}
}
@article{JildehKirchnerBaltesetal.2019,
  author    = {Jildeh, Zaid B. and Kirchner, Patrick and Baltes, Klaus and Wagner, Patrick H. and Sch{\"o}ning, Michael Josef},
  title     = {Development of an in-line evaporation unit for the production of gas mixtures containing hydrogen peroxide - numerical modeling and experimental results},
  series = {International Journal of Heat and Mass Transfer},
  volume    = {143},
  journal   = {International Journal of Heat and Mass Transfer},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0017-9310},
  doi       = {10.1016/j.ijheatmasstransfer.2019.118519},
  pages     = {Article number 118519},
  year      = {2019},
  abstract  = {Hydrogen peroxide (H2O2) is a typical surface sterilization agent for packaging materials used in the pharmaceutical, food and beverage industries. We use the finite-elements method to analyze the conceptual design of an in-line thermal evaporation unit to produce a heated gas mixture of air and evaporated H2O2 solution. For the numerical model, the required phase-transition variables of pure H2O2 solution and of the aerosol mixture are acquired from vapor-liquid equilibrium (VLE) diagrams derived from vapor-pressure formulations. This work combines homogeneous single-phase turbulent flow with heat-transfer physics to describe the operation of the evaporation unit. We introduce the apparent heat-capacity concept to approximate the non-isothermal phase-transition process of the H2O2-containing aerosol. Empirical and analytical functions are defined to represent the temperature- and pressure-dependent material properties of the aqueous H2O2 solution, the aerosol and the gas mixture. To validate the numerical model, the simulation results are compared to experimental data on the heating power required to produce the gas mixture. This shows good agreement with the deviations below 10\%. Experimental observations on the formation of deposits due to the evaporation of stabilized H2O2 solution fits the prediction made from simulation results.},
  language  = {en}
}
@article{TurlybekulyPogrebnjakSukhodubetal.2019,
  author    = {Turlybekuly, Amanzhol and Pogrebnjak, Alexander and Sukhodub, L. F. and Sukhodub, Liudmyla B. and Kistaubayeva, A. S. and Savitskaya, Irina and Shokatayeva, D. H. and Bondar, Oleksandr V. and Shaimardanov, Z. K. and Plotnikov, Sergey V. and Shaimardanova, B. H. and Digel, Ilya},
  title     = {Synthesis, characterization, in vitro biocompatibility and antibacterial properties study of nanocomposite materials based on hydroxyapatite-biphasic ZnO micro- and nanoparticles embedded in Alginate matrix},
  series = {Materials Science and Engineering C},
  volume    = {104},
  journal   = {Materials Science and Engineering C},
  number    = {Article number 109965},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.msec.2019.109965},
  year      = {2019},
  language  = {en}
}
@article{WerkhausenCroninAlbrachtetal.2019,
  author    = {Werkhausen, Amelie and Cronin, Neil J. and Albracht, Kirsten and Bojsen-M{\o}ller, Jens and Seynnes, Olivier R.},
  title     = {Distinct muscle-tendon interaction during running at different speeds and in different loading conditions},
  series = {Journal of Applied Physiology},
  volume    = {127},
  journal   = {Journal of Applied Physiology},
  number    = {1},
  issn      = {1522-1601},
  doi       = {10.1152/japplphysiol.00710.2018},
  pages     = {246 -- 253},
  year      = {2019},
  language  = {en}
}
@article{QuittmannAbelAlbrachtetal.2019,
  author    = {Quittmann, Oliver J. and Abel, Thomas and Albracht, Kirsten and Str{\"u}der, Heiko K.},
  title     = {Reliability of muscular activation patterns and their alterations during incremental handcycling in able-bodied participants},
  series = {Sports Biomechanics},
  journal   = {Sports Biomechanics},
  number    = {Article in press},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1752-6116},
  doi       = {10.1080/14763141.2019.1593496},
  year      = {2019},
  language  = {en}
}
@incollection{SchoeningWagnerPoghossianetal.2018,
  author    = {Sch{\"o}ning, Michael Josef and Wagner, Torsten and Poghossian, Arshak and Miyamoto, K.I. and Werner, C.F. and Krause, S. and Yoshinobu, T.},
  title     = {Light-addressable potentiometric sensors for (bio-)chemical sensing and imaging},
  series = {Encyclopedia of Interfacial Chemistry: Surface Science and Electrochemistry. Vol. 7},
  booktitle = {Encyclopedia of Interfacial Chemistry: Surface Science and Electrochemistry. Vol. 7},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {9780128097397},
  pages     = {295 -- 308},
  year      = {2018},
  language  = {en}
}
@article{CapriMorsianiSantoroetal.2019,
  author    = {Capri, Miriam and Morsiani, Cristina and Santoro, Aurelia and Moriggi, Manuela and Conte, Maria and Martucci, Morena and Bellavista, Elena and Fabbri, Cristina and Giampieri, Enrico and Albracht, Kirsten and Fl{\"u}ck, Martin and Ruoss, Severin and Brocca, Lorenza and Canepari, Monica and Longa, Emanuela and Giulio, Irene Di and Bottinelli, Roberto and Cerretelli, Paolo and Salvioli, Stefano and Gelfi, Cecilia and Franceschi, Claudio and Narici, Marco and Rittweger, J{\"o}rn},
  title     = {Recovery from 6-month spaceflight at the International Space Station: muscle-related stress into a proinflammatory setting},
  series = {The FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  volume    = {33},
  journal   = {The FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  number    = {4},
  doi       = {10.1096/fj.201801625R},
  pages     = {5168 -- 5180},
  year      = {2019},
  language  = {en}
}
@article{IkenBronderGoretzkietal.2019,
  author    = {Iken, Heiko and Bronder, Thomas and Goretzki, Alexander and Kriesel, Jana and Ahlborn, Kristina and Gerlach, Frank and Vonau, Winfried and Zander, Willi and Schubert, J{\"u}rgen and Sch{\"o}ning, Michael Josef},
  title     = {Development of a Combined pH- and Redox-Sensitive Bi-Electrode Glass Thin-Film Sensor},
  series = {physica status solidi a : applications and materials sciences},
  volume    = {216},
  journal   = {physica status solidi a : applications and materials sciences},
  number    = {12},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201900114},
  pages     = {1 -- 8},
  year      = {2019},
  language  = {en}
}
@article{DantismRoehlenSelmeretal.2019,
  author    = {Dantism, Shahriar and R{\"o}hlen, Desiree and Selmer, Thorsten and Wagner, Torsten and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Quantitative differential monitoring of the metabolic activity of Corynebacterium glutamicum cultures utilizing a light-addressable potentiometric sensor system},
  series = {Biosensors and Bioelectronics},
  volume    = {139},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.bios.2019.111332},
  pages     = {Artikel 111332},
  year      = {2019},
  language  = {en}
}
@article{GerhardsSanderZivkovicetal.2020,
  author    = {Gerhards, Michael and Sander, Volker and Zivkovic, Miroslav and Belloum, Adam and Bubak, Marian},
  title     = {New approach to allocation planning of many-task workflows on clouds},
  series = {Concurrency and Computation: Practice and Experience},
  volume    = {32},
  journal   = {Concurrency and Computation: Practice and Experience},
  number    = {2 Article e5404},
  publisher = {Wiley},
  address   = {Chichester},
  issn      = {1532-0634},
  doi       = {10.1002/cpe.5404},
  pages     = {1 -- 16},
  year      = {2020},
  abstract  = {Experience has shown that a priori created static resource allocation plans are vulnerable to runtime deviations and hence often become uneconomic or highly exceed a predefined soft deadline. The assumption of constant task execution times during allocation planning is even more unlikely in a cloud environment where virtualized resources vary in performance. Revising the initially created resource allocation plan at runtime allows the scheduler to react on deviations between planning and execution. Such an adaptive rescheduling of a many-task application workflow is only feasible, when the planning time can be handled efficiently at runtime. In this paper, we present the static low-complexity resource allocation planning algorithm (LCP) applicable to efficiently schedule many-task scientific application workflows on cloud resources of different capabilities. The benefits of the presented algorithm are benchmarked against alternative approaches. The benchmark results show that LCP is not only able to compete against higher complexity algorithms in terms of planned costs and planned makespan but also outperforms them significantly by magnitudes of 2 to 160 in terms of required planning time. Hence, LCP is superior in terms of practical usability where low planning time is essential such as in our targeted online rescheduling scenario.},
  language  = {en}
}
@article{KodomskoiKotliarSchroederetal.2019,
  author    = {Kodomskoi, Leonid and Kotliar, Konstantin and Schr{\"o}der, Andreas and Weiss, Michael and Hille, Konrad},
  title     = {Suture-Probe Canaloplasty as an Alternative to Canaloplasty using the iTrack™ Microcatheter},
  series = {Journal of Glaucoma},
  journal   = {Journal of Glaucoma},
  number    = {Epub ahead of print},
  publisher = {Lippincott Williams \& Wilkins},
  address   = {Philadelphia},
  issn      = {1057-0829},
  doi       = {10.1097/IJG.0000000000001321},
  year      = {2019},
  language  = {en}
}
@inproceedings{SiebigterothKraftSchmidtsetal.2019,
  author    = {Siebigteroth, Ines and Kraft, Bodo and Schmidts, Oliver and Z{\"u}ndorf, Albert},
  title     = {A Study on Improving Corpus Creation by Pair Annotation},
  series = {Proceedings of the Poster Session of the 2nd Conference on Language, Data and Knowledge (LDK-PS 2019)},
  booktitle = {Proceedings of the Poster Session of the 2nd Conference on Language, Data and Knowledge (LDK-PS 2019)},
  issn      = {1613-0073},
  pages     = {40 -- 44},
  year      = {2019},
  language  = {en}
}
@inproceedings{BlumAlbannaBenninghausetal.2019,
  author    = {Blum, Yannik and Albanna, Walid and Benninghaus, Anne and Kotliar, Konstantin},
  title     = {Vasomotion in retinal vessels of patients presenting post hemorrhagic hydrocephalus following subarachnoid hemorrhage},
  series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen},
  booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen},
  editor    = {Staat, Manfred and Erni, Daniel},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-22-6},
  doi       = {10.17185/duepublico/48750},
  pages     = {38 -- 39},
  year      = {2019},
  abstract  = {Clearance of blood components and fluid drainage play a crucial role in subarachnoid hemorrhage (SAH) and post hemorrhagic hydrocephalus (PHH). With the involvement of interstitial fluid (ISF) and cerebrospinal fluid (CSF), two pathways for the clearance of fluid and solutes in the brain are proposed. Starting at the level of capillaries, flow of ISF follows along the basement membranes in the walls of cerebral arteries out of the parenchyma to drain into the lymphatics and CSF [1]-[3]. Conversely, it is shown that CSF enters the parenchyma between glial and pial basement membranes of penetrating arteries [4]-[6]. Nevertheless, the involved structures and the contribution of either flow pathway to fluid balance between the subarachnoid space and interstitial space remains controversial. Low frequency oscillations in vascular tone are referred to as vasomotion and corresponding vasomotion waves are modeled as the driving force for flow of ISF out of the parenchyma [7]. Retinal vessel analysis (RVA) allows non-invasive measurement of retinal vessel vasomotion with respect to diameter changes [8]. Thus, the aim of the study is to investigate vasomotion in RVA signals of SAH and PHH patients.},
  language  = {en}
}
@inproceedings{ZingsheimGrimmerOrtneretal.2019,
  author    = {Zingsheim, Jonas and Grimmer, Timo and Ortner, Marion and Schmaderer, Christoph and Hauser, Christine and Kotliar, Konstantin},
  title     = {Recognition of subjects with mild cognitive impairment (MCI) by the use of retinal arterial vessels.},
  series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen},
  booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen},
  editor    = {Staat, Manfred and Erni, Daniel},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-22-6},
  doi       = {10.17185/duepublico/48750},
  pages     = {36 -- 37},
  year      = {2019},
  language  = {en}
}
@inproceedings{AzarDigel2019,
  author    = {Azar, Fouad and Digel, Ilya},
  title     = {Utilization of fluorescence spectroscopy and neural networks in clinical analysis},
  series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen},
  booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen},
  editor    = {Staat, Manfred and Erni, Daniel},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-22-6},
  doi       = {10.17185/duepublico/48750},
  pages     = {40 -- 41},
  year      = {2019},
  abstract  = {Fluorescence topography of human urine in combination with learning algorithms can provide a variant pattern recognition method in analytical clinical chemistry and, eventually, diagnosis.},
  language  = {en}
}
@inproceedings{BayerHeschelerArtmannetal.2019,
  author    = {Bayer, Robin and Hescheler, J{\"u}rgen and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {Treating arterial hypertension in a cell culture well},
  series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH AachenW},
  booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH AachenW},
  editor    = {Staat, Manfred and Erni, Daniel},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-22-6},
  doi       = {10.17185/duepublico/48750},
  pages     = {5 -- 6},
  year      = {2019},
  abstract  = {Hypertension describes the pathological increase of blood pressure, which is most commonly associated with the increase of vascular wall stiffness [1]. Referring to the "Deutsche Bluthochdruck Liga" this pathology shows a growing trend in our aging society. In order to find novel pharmacological and probably personalized treatments, we want to present a functional approach to study biomechanical properties of a human aortic vascular model. In this method review we will give an overview of recent studies which were carried out with the CellDrum technology [2] and underline the added value to already existing standard procedures known from the field of physiology. Herein described CellDrum technology is a system to measure functional mechanical properties of cell monolayers and thin tissue constructs in-vitro. Additionally, the CellDrum enables to elucidate the mechanical response of cells to pharmacological drugs, toxins and vasoactive agents. Due to its highly flexible polymer support, cells can also be mechanically stimulated by steady and cyclic biaxial stretching.},
  language  = {en}
}
@article{KoppSchmeetsGosauetal.2019,
  author    = {Kopp, Alexander and Schmeets, Ralf and Gosau, Martin and Friedrich, Reinhard E. and Fuest, Sandra and Behbahani, Mehdi and Barbeck, Mike and Rutkowski, Rico and Burg, Simon and Kluwe, Lan and Henningsen, Anders},
  title     = {Production and Characterization of Porous Fibroin Scaffolds for Regenerative Medical Application},
  series = {In Vivo},
  volume    = {33},
  journal   = {In Vivo},
  number    = {3},
  issn      = {1791-7549},
  doi       = {10.21873/invivo.11536},
  pages     = {757 -- 762},
  year      = {2019},
  language  = {en}
}
@article{Stulpe2019,
  author    = {Stulpe, Werner},
  title     = {Aspects of the Quantum-Classical Connection Based on Statistical Maps},
  series = {Foundations of Physics},
  volume    = {49},
  journal   = {Foundations of Physics},
  number    = {6},
  publisher = {Springer},
  address   = {Berlin},
  doi       = {10.1007/s10701-019-00269-9},
  pages     = {677 -- 692},
  year      = {2019},
  language  = {en}
}
@phdthesis{Geenen2013,
  author    = {Geenen, Eva-Maria},
  title     = {Studies of Epstein-Barr virus EBNA2 and its interactions with host cell factors},
  publisher = {Universit{\´e} de Grenoble},
  address   = {Grenoble},
  pages     = {125 S.},
  year      = {2013},
  language  = {en}
}
@inproceedings{RamanJungHorvathetal.2019,
  author    = {Raman, Aravind Hariharan and Jung, Alexander and Horv{\´a}th, Andr{\´a}s and Becker, Nadine and Staat, Manfred},
  title     = {Modification of a computer model of human stem cell-derived cardiomyocyte electrophysiology based on Patch-Clamp measurements},
  series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen},
  booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen},
  editor    = {Staat, Manfred and Erni, Daniel},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-22-6},
  doi       = {10.17185/duepublico/48750},
  pages     = {10 -- 11},
  year      = {2019},
  abstract  = {Human induced pluripotent stem cells (hiPSCs) have shown to be promising in disease studies and drug screenings [1]. Cardiomyocytes derived from hiPSCs have been extensively investigated using patch-clamping and optical methods to compare their electromechanical behaviour relative to fully matured adult cells. Mathematical models can be used for translating findings on hiPSCCMs to adult cells [2] or to better understand the mechanisms of various ion channels when a drug is applied [3,4]. Paci et al. (2013) [3] developed the first model of hiPSC-CMs, which they later refined based on new data [3]. The model is based on iCells® (Fujifilm Cellular Dynamics, Inc. (FCDI), Madison WI, USA) but major differences among several cell lines and even within a single cell line have been found and motivate an approach for creating sample-specific models. We have developed an optimisation algorithm that parameterises the conductances (in S/F=Siemens/Farad) of the latest Paci et al. model (2018) [5] using current-voltage data obtained in individual patch-clamp experiments derived from an automated patch clamp system (Patchliner, Nanion Technologies GmbH, Munich).},
  language  = {en}
}
@inproceedings{HunkerJungGossmannetal.2019,
  author    = {Hunker, Jan and Jung, Alexander and Goßmann, Matthias and Linder, Peter and Staat, Manfred},
  title     = {Development of a tool to analyze the conduction speed in microelectrode array measurements of cardiac tissue},
  series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen},
  booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen},
  editor    = {Staat, Manfred and Erni, Daniel},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-22-6},
  doi       = {10.17185/duepublico/48750},
  pages     = {7 -- 8},
  year      = {2019},
  abstract  = {The discovery of human induced pluripotent stem cells reprogrammed from somatic cells [1] and their ability to differentiate into cardiomyocytes (hiPSC-CMs) has provided a robust platform for drug screening [2]. Drug screenings are essential in the development of new components, particularly for evaluating the potential of drugs to induce life-threatening pro-arrhythmias. Between 1988 and 2009, 14 drugs have been removed from the market for this reason [3]. The microelectrode array (MEA) technique is a robust tool for drug screening as it detects the field potentials (FPs) for the entire cell culture. Furthermore, the propagation of the field potential can be examined on an electrode basis. To analyze MEA measurements in detail, we have developed an open-source tool.},
  language  = {en}
}
@book{StaatErni2019,
  author    = {Staat, Manfred and Erni, Daniel},
  title     = {Symposium Proceedings; 3rd YRA MedTech Symposium 2019: May 24 / 2019 / FH Aachen},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-22-6},
  doi       = {10.17185/duepublico/48750},
  pages     = {49 Seiten},
  year      = {2019},
  language  = {en}
}
@inproceedings{SchmidtsKraftSiebigterothetal.2019,
  author    = {Schmidts, Oliver and Kraft, Bodo and Siebigteroth, Ines and Z{\"u}ndorf, Albert},
  title     = {Schema Matching with Frequent Changes on Semi-Structured Input Files: A Machine Learning Approach on Biological Product Data},
  series = {Proceedings of the 21st International Conference on Enterprise Information Systems - Volume 1: ICEIS},
  booktitle = {Proceedings of the 21st International Conference on Enterprise Information Systems - Volume 1: ICEIS},
  isbn      = {978-989-758-372-8},
  doi       = {10.5220/0007723602080215},
  pages     = {208 -- 215},
  year      = {2019},
  language  = {en}
}
@article{PoghossianGeisslerSchoening2019,
  author    = {Poghossian, Arshak and Geissler, Hanno and Sch{\"o}ning, Michael Josef},
  title     = {Rapid methods and sensors for milk quality monitoring and spoilage detection},
  series = {Biosensors and Bioelectronics},
  volume    = {140},
  journal   = {Biosensors and Bioelectronics},
  number    = {Article 111272},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2019.04.040},
  year      = {2019},
  language  = {en}
}
@article{CornelisGivanoudiYongabietal.2019,
  author    = {Cornelis, Peter and Givanoudi, Stella and Yongabi, Derick and Iken, Heiko and Duw{\´e}, Sam and Deschaume, Olivier and Robbens, Johan and Dedecker, Peter and Bartic, Carmen and W{\"u}bbenhorst, Michael and Sch{\"o}ning, Michael Josef and Heyndrickx, Marc and Wagner, Patrick},
  title     = {Sensitive and specific detection of E. coli using biomimetic receptors in combination with a modified heat-transfer method},
  series = {Biosensors and Bioelectronics},
  volume    = {136},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2019.04.026},
  pages     = {97 -- 105},
  year      = {2019},
  language  = {en}
}
@article{MeyerGaalenLeschingeretal.2019,
  author    = {Meyer, Carolin and Gaalen, Kerstin van and Leschinger, Tim and Scheyerer, Max J. and Neiss, Wolfram F. and Staat, Manfred and M{\"u}ller, Lars P. and Wegmann, Kilian},
  title     = {Kyphoplasty of Osteoporotic Fractured Vertebrae: A Finite Element Analysis about Two Types of Cement},
  series = {BioMed Research International},
  journal   = {BioMed Research International},
  doi       = {10.1155/2019/9232813},
  pages     = {Article ID 9232813},
  year      = {2019},
  language  = {en}
}
@article{TranStaat2020,
  author    = {Tran, Ngoc Trinh and Staat, Manfred},
  title     = {Direct plastic structural design under lognormally distributed strength by chance constrained programming},
  series = {Optimization and Engineering},
  volume    = {21},
  journal   = {Optimization and Engineering},
  number    = {1},
  publisher = {Springer Nature},
  address   = {Cham},
  issn      = {1573-2924},
  doi       = {10.1007/s11081-019-09437-2},
  pages     = {131 -- 157},
  year      = {2020},
  abstract  = {We propose the so-called chance constrained programming model of stochastic programming theory to analyze limit and shakedown loads of structures under random strength with a lognormal distribution. A dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit and the shakedown limit. The edge-based smoothed finite element method (ES-FEM) is used with three-node linear triangular elements.},
  language  = {en}
}
@article{AlbannaLuekeSchubertetal.2019,
  author    = {Albanna, Walid and L{\"u}ke, Jan Niklas and Schubert, Gerrit Alexander and Dibu{\´e}-Adjei, Maxine and Kotliar, Konstantin and Hescheler, J{\"u}rgen and Clusmann, Hans and Steiger, Hans-Jakob and H{\"a}nggi, Daniel and Kamp, Marcel A. and Schneider, Toni and Neumaier, Felix},
  title     = {Modulation of Ca v 2.3 channels by unconjugated bilirubin (UCB) - Candidate mechanism for UCB-induced neuromodulation and neurotoxicity},
  series = {Molecular and Cellular Neuroscience},
  volume    = {96},
  journal   = {Molecular and Cellular Neuroscience},
  number    = {4},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1044-7431},
  doi       = {10.1016/j.mcn.2019.03.003},
  pages     = {35 -- 46},
  year      = {2019},
  language  = {en}
}
@article{MoraisSilvaDantasetal.2019,
  author    = {Morais, Paulo V. and Silva, Anielle C. A. and Dantas, Noelio O. and Sch{\"o}ning, Michael Josef and Siqueira, Jos{\´e} R., Jr.},
  title     = {Hybrid Layer-by-Layer Film of Polyelectrolytes-Embedded Catalytic CoFe2O4 Nanocrystals as Sensing Units in Capacitive Electrolyte-Insulator-Semiconductor Devices},
  series = {physica status solidi a : applications and materials sciences},
  volume    = {216},
  journal   = {physica status solidi a : applications and materials sciences},
  number    = {1900044},
  publisher = {Wiley},
  address   = {Weinheim},
  doi       = {10.1002/pssa.201900044},
  pages     = {1 -- 9},
  year      = {2019},
  language  = {en}
}
@article{VoegeleRuebbelkeGovorukhaetal.2019,
  author    = {V{\"o}gele, Stefan and R{\"u}bbelke, Dirk and Govorukha, Kristina and Grajewski, Matthias},
  title     = {Socio-technical scenarios for energy-intensive industries: the future of steel production in Germany},
  series = {Climatic Change},
  journal   = {Climatic Change},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0165-0009},
  doi       = {10.1007/s10584-019-02366-0},
  pages     = {1 -- 16},
  year      = {2019},
  language  = {en}
}
@article{BreuerPilasGuthmannetal.2019,
  author    = {Breuer, Lars and Pilas, Johanna and Guthmann, Eric and Sch{\"o}ning, Michael Josef and Thoelen, Ronald and Wagner, Torsten},
  title     = {Towards light-addressable flow control: responsive hydrogels with incorporated graphene oxide as laser-driven actuator structures within microfluidic channels},
  series = {Sensor and Actuators B: Chemical},
  volume    = {288},
  journal   = {Sensor and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2019.02.086},
  pages     = {579 -- 585},
  year      = {2019},
  language  = {en}
}
@article{JungMuellerStaat2019,
  author    = {Jung, Alexander and M{\"u}ller, Wolfram and Staat, Manfred},
  title     = {Optimization of the flight technique in ski jumping: the influence of wind},
  number    = {Early view},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.jbiomech.2019.03.023},
  year      = {2019},
  language  = {en}
}
@article{LeschingerBirgelHackletal.2019,
  author    = {Leschinger, Tim and Birgel, Stefan and Hackl, Michael and Staat, Manfred and M{\"u}ller, Lars Peter and Wegmann, Kilian},
  title     = {A musculoskeletal shoulder simulation of moment arms and joint reaction forces after medialization of the supraspinatus footprint in rotator cuff repair},
  series = {Computer Methods in Biomechanics and Biomedical Engineering},
  journal   = {Computer Methods in Biomechanics and Biomedical Engineering},
  number    = {Early view},
  publisher = {Taylor \& Francis},
  address   = {London},
  doi       = {10.1080/10255842.2019.1572749},
  year      = {2019},
  language  = {en}
}
@article{BleilevensHillGrzannaetal.2019,
  author    = {Bleilevens, Christian and Hill, Aileen and Grzanna, Tim and Fechter, Tamara and Bohnen, Melanie and Weber, Hans-Joachim and Beckers, Christian and Borosch, Sebastian and Zayat, Rashad and Benstoem, Carin and Rossaint, Rolf and Goetzenich, Andreas},
  title     = {In vitro head-to-head comparison of anticoagulation properties of two heparin brands in a human blood miniature mock loop},
  series = {Interactive cardiovascular and thoracic surgery},
  volume    = {28},
  journal   = {Interactive cardiovascular and thoracic surgery},
  number    = {1},
  issn      = {1569-9285},
  doi       = {10.1093/icvts/ivy206},
  pages     = {120 -- 127},
  year      = {2019},
  language  = {en}
}
@article{HeinkeKnickerAlbracht2018,
  author    = {Heinke, Lars N. and Knicker, Axel J. and Albracht, Kirsten},
  title     = {Evaluation of passively induced shoulder stretch reflex using an isokinetic dynamometer in male overhead athletes},
  series = {Isokinetics and Exercise Science},
  volume    = {26},
  journal   = {Isokinetics and Exercise Science},
  number    = {4},
  publisher = {IOS Press},
  address   = {Amsterdam},
  issn      = {1878-5913},
  doi       = {10.3233/IES-184111},
  pages     = {265 -- 274},
  year      = {2018},
  abstract  = {BACKGROUND: Muscle stretch reflexes are widely considered to beneficially influence joint stability and power generation in the lower limbs. While in the upper limbs and especially in the muscles surrounding the shoulder joint such evidence is lacking. OBJECTIVE: To quantify the electromyographical response in the muscles crossing the shoulder of specifically trained overhead athletes to an anterior perturbation force. METHODS: Twenty healthy male participants performed six sets of different external shoulder rotation stretches on an isokinetic dynamometer over a range of amplitudes and muscle pre-activation moment levels. All stretches were applied with a dynamometer acceleration of 10,000∘/s2 and a velocity of 150∘/s. Electromyographical response was measured via sEMG. RESULTS: Consistent reflexes were not observed in all experimental conditions. The reflex latencies revealed a significant muscle main effect (F (2,228) = 99.31, p< 0.001; η2= 0.466; f= 0.934) and a pre-activation main effect (F (1,228) = 142.21, p< 0.001; η2= 0.384; f= 1.418). The stretch reflex amplitude yielded a significant pre-activation main effect (F (1,222) = 470.373, p< 0.001; η2= 0.679; f= 1.454). CONCLUSION: Short latency muscle reflexes showed a tendency to an anterior to posterior muscle recruitment whereby the main internal rotator muscles of the shoulder revealed the most consistent results.},
  language  = {en}
}
@article{LauraDrechslerErdtetal.2018,
  author    = {Laura, C.O. and Drechsler, Klaus and Erdt, M. and Wesarg, S. and Bale, R.},
  title     = {Intervention assessment tool for primary tumors in the liver},
  series = {Current Directions in Biomedical Engineering},
  volume    = {4},
  journal   = {Current Directions in Biomedical Engineering},
  number    = {1},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {2364-5504},
  doi       = {10.1515/cdbme-2018-0081},
  pages     = {337 -- 340},
  year      = {2018},
  abstract  = {After a liver tumor intervention the medical doctor has to compare both pre and postoperative CT acquisitions to ensure that all carcinogenic cells are destroyed. A correct assessment of the intervention is of vital importance, since it will reduce the probability of tumor recurrence. Some methods have been proposed to support the medical doctors during the assessment process, however, all of them focus on secondary tumors. In this paper a tool is presented that enables the outcome validation for both primary and secondary tumors. Therefore, a multiphase registration (preoperative arterial and portal phases) followed by a registration between the pre and postoperative CT images is carried out. The first registration is in charge of the primary tumors that are only visible in the arterial phase. The secondary tumors will be incorporated in the second registration step. Finally, the part of the tumor that was not covered by the necrosis is quantified and visualized. The method has been tested in 9 patients, with an average registration error of 1.41 mm.},
  language  = {en}
}
@article{BronderPoghossianJessingetal.2019,
  author    = {Bronder, Thomas and Poghossian, Arshak and Jessing, Max P. and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Surface regeneration and reusability of label-free DNA biosensors based on weak polyelectrolyte-modified capacitive field-effect structures},
  series = {Biosensors and Bioelectronics},
  volume    = {126},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2018.11.019},
  pages     = {510 -- 517},
  year      = {2019},
  language  = {en}
}
@article{ArreolaKeusgenSchoening2019,
  author    = {Arreola, Julio and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Toward an immobilization method for spore-based biosensors in oxidative environment},
  series = {Electrochimica Acta},
  volume    = {302},
  journal   = {Electrochimica Acta},
  publisher = {Elsevier},
  address   = {Amsterdam},
  doi       = {10.1016/j.electacta.2019.01.148},
  pages     = {394 -- 401},
  year      = {2019},
  language  = {en}
}
@article{JungStaat2019,
  author    = {Jung, Alexander and Staat, Manfred},
  title     = {Modeling and simulation of human induced pluripotent stem cell-derived cardiac tissue},
  series = {GAMM - Mitteilungen der Gesellschaft f{\"u}r Angewandte Mathematik und Mechanik},
  volume    = {42},
  journal   = {GAMM - Mitteilungen der Gesellschaft f{\"u}r Angewandte Mathematik und Mechanik},
  number    = {4},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1522-2608},
  doi       = {10.1002/gamm.201900002},
  pages     = {11 Seiten},
  year      = {2019},
  language  = {en}
}
@inproceedings{RichterBraunsteinStaeudleetal.2018,
  author    = {Richter, Charlotte and Braunstein, Bjoern and St{\"a}udle, Benjamin and Attias, Julia and Suess, Alexander and Weber, T. and Rittweger, Joern and Green, David A. and Albracht, Kirsten},
  title     = {In vivo fascicle length of the gastrocnemius muscle during walking in simulated martian gravity using two different body weight support devices},
  series = {23rd Annual Congress of the European College of Sport Science, Dublin, Irland},
  booktitle = {23rd Annual Congress of the European College of Sport Science, Dublin, Irland},
  year      = {2018},
  language  = {en}
}
@article{RichterBraunsteinWinnardetal.2017,
  author    = {Richter, Charlotte and Braunstein, Bjoern and Winnard, Andrew and Nasser, Mona and Weber, T.},
  title     = {Human Biomechanical and Cardiopulmonary Responses to Partial Gravity - A Systematic Review},
  series = {Frontiers in physiology},
  journal   = {Frontiers in physiology},
  number    = {8, article 583},
  doi       = {10.3389/fphys.2017.00583},
  pages     = {22 Seiten},
  year      = {2017},
  language  = {en}
}
@inproceedings{BehbahaniRibleMoulinecetal.2015,
  author    = {Behbahani, Mehdi and Rible, Sebastian and Moulinec, Charles and Fournier, Yvan and Nicolai, Mike and Crosetto, Paolo},
  title     = {Simulation of the FDA Centrifugal Blood Pump Using High Performance Computing},
  series = {World Academy of Science, Engineering and Technology International Journal of Mechanical and Mechatronics Engineering},
  volume    = {9},
  booktitle = {World Academy of Science, Engineering and Technology International Journal of Mechanical and Mechatronics Engineering},
  number    = {5},
  year      = {2015},
  language  = {en}
}
@article{BalakirskiKotliarPaulyetal.2018,
  author    = {Balakirski, Galina and Kotliar, Konstantin and Pauly, Karolin J. and Krings, Laura K. and R{\"u}bben, Albert and Baron, Jens M. and Schmitt, Laurenz},
  title     = {Surgical Site Infections After Dermatologic Surgery in Immunocompromised Patients: A Single-Center Experience},
  series = {Dermatologic Surgery},
  journal   = {Dermatologic Surgery},
  number    = {44 (12)},
  publisher = {Wolters Kluwer},
  doi       = {10.1097/DSS.0000000000001615},
  pages     = {1525 -- 1536},
  year      = {2018},
  abstract  = {BACKGROUND Immunosuppression is often considered as an indication for antibiotic prophylaxis to prevent surgical site infections (SSI) while performing skin surgery. However, the data on the risk of developing SSI after dermatologic surgery in immunosuppressed patients are limited. PATIENTS AND METHODS All patients of the Department of Dermatology and Allergology at the University Hospital of RWTH Aachen in Aachen, Germany, who underwent hospitalization for a dermatologic surgery between June 2016 and January 2017 (6 months), were followed up after surgery until completion of the wound healing process. The follow-up addressed the occurrence of SSI and the need for systemic antibiotics after the operative procedure. Immunocompromised patients were compared with immunocompetent patients. The investigation was conducted as a retrospective analysis of patient records. RESULTS The authors performed 284 dermatologic surgeries in 177 patients. Nineteen percent (54/284) of the skin surgery was performed on immunocompromised patients. The most common indications for surgical treatment were nonmelanoma skin cancer and malignant melanomas. Surgical site infections occurred in 6.7\% (19/284) of the cases. In 95\% (18/19), systemic antibiotic treatment was needed. Twenty-one percent of all SSI (4/19) were seen in immunosuppressed patients. CONCLUSION According to the authors' data, immunosuppression does not represent a significant risk factor for SSI after dermatologic surgery. However, larger prospective studies are needed to make specific recommendations on the use of antibiotic prophylaxis while performing skin surgery in these patients. The available data on complications after dermatologic surgery have improved over the past years. Particularly, additional risk factors have been identified for surgical site infections (SSI). Purulent surgical sites, older age, involvement of head, neck, and acral regions, and also the involvement of less experienced surgeons have been reported to increase the risk of the SSI after dermatologic surgeries.1 In general, the incidence of SSI after skin surgery is considered to be low.1,2 However, antibiotics in dermatologic surgeries, especially in the perioperative setting, seem to be overused,3,4 particularly regarding developing antibiotic resistances and side effects. Immunosuppression has been recommended to be taken into consideration as an additional indication for antibiotic prophylaxis to prevent SSI after skin surgery in special cases.5,6 However, these recommendations do not specify the exact dermatologic surgeries, and were not specifically developed for dermatologic surgery patients and treatments, but adopted from other surgical fields.6 According to the survey conducted on American College of Mohs Surgery members in 2012, 13\% to 29\% of the surgeons administered antibiotic prophylaxis to immunocompromised patients to prevent SSI while performing dermatologic surgery on noninfected skin,3 although this was not recommended by Journal of the American Academy of Dermatology Advisory Statement. Indeed, the data on the risk of developing SSI after dermatologic surgery in immunosuppressed patients are limited. However, it is possible that due to the insufficient evidence on the risk of SSI occurrence in this patient group, dermatologic surgeons tend to overuse perioperative antibiotic prophylaxis. To make specific recommendations on the use of antibiotic prophylaxis in immunosuppressed patients in the field of skin surgery, more information about the incidence of SSI after dermatologic surgery in these patients is needed. The aim of this study was to fill this data gap by investigating whether there is an increased risk of SSI after skin surgery in immunocompromised patients compared with immunocompetent patients.},
  language  = {en}
}
@article{JayaramanMummidisettyLoeschetal.2019,
  author    = {Jayaraman, Chandrasekaran and Mummidisetty, Chaitanya Krishna and Loesch, Alexandra and Kaur, Sandi and Hoppe-Ludwig, Shenan and Staat, Manfred and Jayaraman, Arun},
  title     = {Postural and metabolic benefits of using a forearm support walker in older adults with impairments},
  series = {Archives of Physical Medicine and Rehabilitation},
  volume    = {Volume 100},
  journal   = {Archives of Physical Medicine and Rehabilitation},
  number    = {Issue 4},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0003-9993},
  doi       = {10.1016/j.apmr.2018.10.001},
  pages     = {638 -- 647},
  year      = {2019},
  language  = {en}
}
@article{AlbannaKotliarLuekeetal.2018,
  author    = {Albanna, Walid and Kotliar, Konstantin and L{\"u}ke, Jan Niklas and Alpdogan, Serdar and Conzen, Catharina and Lindauer, Ute and Clusmann, Hans and Hescheler, J{\"u}rgen and Vilser, Walthard and Schneider, Toni and Schubert, Gerrit Alexander},
  title     = {Non-invasive evaluation of neurovascular coupling in the murine retina by dynamic retinal vessel analysis},
  series = {Plos one},
  volume    = {13},
  journal   = {Plos one},
  number    = {10},
  publisher = {PLOS},
  address   = {San Francisco},
  doi       = {10.1371/journal.pone.0204689},
  pages     = {e0204689},
  year      = {2018},
  abstract  = {Background Impairment of neurovascular coupling (NVC) was recently reported in the context of subarachnoid hemorrhage and may correlate with disease severity and outcome. However, previous techniques to evaluate NVC required invasive procedures. Retinal vessels may represent an alternative option for non-invasive assessment of NVC. Methods A prototype of an adapted retinal vessel analyzer was used to assess retinal vessel diameter in mice. Dynamic vessel analysis (DVA) included an application of monochromatic flicker light impulses in predefined frequencies for evaluating NVC. All retinae were harvested after DVA and electroretinograms were performed. Results A total of 104 retinal scans were conducted in 21 male mice (90 scans). Quantitative arterial recordings were feasible only in a minority of animals, showing an emphasized reaction to flicker light impulses (8 mice; 14 scans). A characteristic venous response to flicker light, however, could observed in the majority of animals. Repeated measurements resulted in a significant decrease of baseline venous diameter (7 mice; 7 scans, p < 0.05). Ex-vivo electroretinograms, performed after in-vivo DVA, demonstrated a significant reduction of transretinal signaling in animals with repeated DVA (n = 6, p < 0.001). Conclusions To the best of our knowledge, this is the first non-invasive study assessing murine retinal vessel response to flicker light with characteristic changes in NVC. The imaging system can be used for basic research and enables the investigation of retinal vessel dimension and function in control mice and genetically modified animals.},
  language  = {en}
}
@incollection{YoshinobuKrauseMiyamotoetal.2018,
  author    = {Yoshinobu, Tatsuo and Krause, Steffi and Miyamoto, Ko-ichiro and Werner, Frederik and Poghossian, Arshak and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {(Bio-)chemical Sensing and Imaging by LAPS and SPIM},
  series = {Label-free biosensing: advanced materials, devices and applications},
  booktitle = {Label-free biosensing: advanced materials, devices and applications},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-75219-8},
  pages     = {103 -- 132},
  year      = {2018},
  abstract  = {The light-addressable potentiometric sensor (LAPS) and scanning photo-induced impedance microscopy (SPIM) are two closely related methods to visualise the distributions of chemical species and impedance, respectively, at the interface between the sensing surface and the sample solution. They both have the same field-effect structure based on a semiconductor, which allows spatially resolved and label-free measurement of chemical species and impedance in the form of a photocurrent signal generated by a scanning light beam. In this article, the principles and various operation modes of LAPS and SPIM, functionalisation of the sensing surface for measuring various species, LAPS-based chemical imaging and high-resolution sensors based on silicon-on-sapphire substrates are described and discussed, focusing on their technical details and prospective applications.},
  language  = {en}
}
@book{SchoeningPoghossian2018,
  author    = {Sch{\"o}ning, Michael Josef and Poghossian, Arshak},
  title     = {Label-free biosensing: advanced materials, devices and applications},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-75219-8},
  pages     = {xii, 480 Seiten ; Illustrationen, Diagramme},
  year      = {2018},
  language  = {en}
}
@article{RodriguesMoraisNordietal.2018,
  author    = {Rodrigues, Raul T. and Morais, Paulo V. and Nordi, Cristina S. F. and Sch{\"o}ning, Michael Josef and Siqueira Jr., Jos{\´e} R. and Caseli, Luciano},
  title     = {Carbon Nanotubes and Algal Polysaccharides To Enhance the Enzymatic Properties of Urease in Lipid Langmuir-Blodgett Films},
  series = {Langmuir},
  volume    = {34},
  journal   = {Langmuir},
  number    = {9},
  publisher = {ACS Publications},
  address   = {Washington, DC},
  issn      = {1520-5827},
  doi       = {10.1021/acs.langmuir.7b04317},
  pages     = {3082 -- 3093},
  year      = {2018},
  abstract  = {Algal polysaccharides (extracellular polysaccharides) and carbon nanotubes (CNTs) were adsorbed on dioctadecyldimethylammonium bromide Langmuir monolayers to serve as a matrix for the incorporation of urease. The physicochemical properties of the supramolecular system as a monolayer at the air-water interface were investigated by surface pressure-area isotherms, surface potential-area isotherms, interfacial shear rheology, vibrational spectroscopy, and Brewster angle microscopy. The floating monolayers were transferred to hydrophilic solid supports, quartz, mica, or capacitive electrolyte-insulator-semiconductor (EIS) devices, through the Langmuir-Blodgett (LB) technique, forming mixed films, which were investigated by quartz crystal microbalance, fluorescence spectroscopy, and field emission gun scanning electron microscopy. The enzyme activity was studied with UV-vis spectroscopy, and the feasibility of the thin film as a urea sensor was essayed in an EIS sensor device. The presence of CNT in the enzyme-lipid LB film not only tuned the catalytic activity of urease but also helped to conserve its enzyme activity. Viability as a urease sensor was demonstrated with capacitance-voltage and constant capacitance measurements, exhibiting regular and distinctive output signals over all concentrations used in this work. These results are related to the synergism between the compounds on the active layer, leading to a surface morphology that allowed fast analyte diffusion owing to an adequate molecular accommodation, which also preserved the urease activity. This work demonstrates the feasibility of employing LB films composed of lipids, CNT, algal polysaccharides, and enzymes as EIS devices for biosensing applications.},
  language  = {en}
}
@article{RoehlenPilasDahmenetal.2018,
  author    = {R{\"o}hlen, Desiree and Pilas, Johanna and Dahmen, Markus and Keusgen, Michael and Selmer, Thorsten and Sch{\"o}ning, Michael Josef},
  title     = {Toward a Hybrid Biosensor System for Analysis of Organic and Volatile Fatty Acids in Fermentation Processes},
  series = {Frontiers in Chemistry},
  journal   = {Frontiers in Chemistry},
  number    = {6},
  publisher = {Frontiers},
  address   = {Lausanne},
  doi       = {10.3389/fchem.2018.00284},
  pages     = {Artikel 284},
  year      = {2018},
  abstract  = {Monitoring of organic acids (OA) and volatile fatty acids (VFA) is crucial for the control of anaerobic digestion. In case of unstable process conditions, an accumulation of these intermediates occurs. In the present work, two different enzyme-based biosensor arrays are combined and presented for facile electrochemical determination of several process-relevant analytes. Each biosensor utilizes a platinum sensor chip (14 × 14 mm²) with five individual working electrodes. The OA biosensor enables simultaneous measurement of ethanol, formate, d- and l-lactate, based on a bi-enzymatic detection principle. The second VFA biosensor provides an amperometric platform for quantification of acetate and propionate, mediated by oxidation of hydrogen peroxide. The cross-sensitivity of both biosensors toward potential interferents, typically present in fermentation samples, was investigated. The potential for practical application in complex media was successfully demonstrated in spiked sludge samples collected from three different biogas plants. Thereby, the results obtained by both of the biosensors were in good agreement to the applied reference measurements by photometry and gas chromatography, respectively. The proposed hybrid biosensor system was also used for long-term monitoring of a lab-scale biogas reactor (0.01 m³) for a period of 2 months. In combination with typically monitored parameters, such as gas quality, pH and FOS/TAC (volatile organic acids/total anorganic carbonate), the amperometric measurements of OA and VFA concentration could enhance the understanding of ongoing fermentation processes.},
  language  = {en}
}
@article{LapitanRogatkinPersheyevetal.2018,
  author    = {Lapitan, Denis G. and Rogatkin, Dmitrii A. and Persheyev, Sydulla K. and Kotliar, Konstantin},
  title     = {False spectra formation in the differential two-channel scheme of the laser Doppler flowmeter},
  series = {Biomedizinische Technik},
  volume    = {63},
  journal   = {Biomedizinische Technik},
  number    = {4},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {0013-5585},
  doi       = {10.1515/bmt-2017-0060},
  pages     = {439 -- 444},
  year      = {2018},
  abstract  = {Noise in the differential two-channel scheme of a classic laser Doppler flowmetry (LDF) instrument was studied. Formation of false spectral components in the output signal due to beating of electrical signals in the differential amplifier was found out. The improved block-diagram of the flowmeter was developed allowing to reduce the noise.},
  language  = {en}
}
@article{MiyamotoSekiSutoetal.2018,
  author    = {Miyamoto, Koichiro and Seki, Kosuke and Suto, Takeyuki and Werner, Frederik and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo},
  title     = {Improved spatial resolution of the chemical imaging sensor with a hybrid illumination that suppresses lateral diffusion of photocarriers},
  series = {Sensor and Actuators B: Chemical},
  volume    = {273},
  journal   = {Sensor and Actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2018.07.016},
  pages     = {1328 -- 1333},
  year      = {2018},
  abstract  = {The chemical imaging sensor is a semiconductor-based chemical sensor capable of visualizing pH and ion distributions. The spatial resolution depends on the lateral diffusion of photocarriers generated by illumination of the semiconductor substrate. In this study, two types of optical setups, one based on a bundle of optical fibers and the other based on a binocular tube head, were developed to project a hybrid illumination of a modulated light beam and a ring-shaped constant illumination onto the sensor plate. An improved spatial resolution was realized by the ring-shaped constant illumination, which suppressed lateral diffusion of photocarriers by enhanced recombination due to the increased carrier concentration.},
  language  = {en}
}
@article{RittwegerAlbrachtFluecketal.2018,
  author    = {Rittweger, J{\"o}rn and Albracht, Kirsten and Fl{\"u}ck, Martin and Ruoss, Severin and Brocca, Lorenza and Longa, Emanuela and Moriggi, Manuela and Seynnes, Olivier and Di Giulio, Irene and Tenori, Leonardo and Vignoli, Alessia and Capri, Miriam and Gelfi, Cecilia and Luchinat, Claudio and Franceschi, Claudio and Bottinelli, Roberto and Cerretelli, Paolo and Narici, Marco},
  title     = {Sarcolab pilot study into skeletal muscle's adaptation to longterm spaceflight},
  series = {npj Microgravity},
  volume    = {4},
  journal   = {npj Microgravity},
  number    = {1},
  publisher = {Nature Portfolio},
  issn      = {2373-8065},
  doi       = {10.1038/s41526-018-0052-1},
  pages     = {1 -- 9},
  year      = {2018},
  language  = {en}
}
@article{BialonskiWellmerElgeretal.2006,
  author    = {Bialonski, Stephan and Wellmer, J{\"o}rg and Elger, Christian E. and Lehnertz, Klaus},
  title     = {Interictal focus localization in neocortical lesional epilepsies with synchronization cluster analysis},
  series = {Epilepsia},
  volume    = {47},
  journal   = {Epilepsia},
  issn      = {0013-9580},
  pages     = {36},
  year      = {2006},
  language  = {en}
}
@article{BialonskiLehnertz2006,
  author    = {Bialonski, Stephan and Lehnertz, Klaus},
  title     = {Identifying phase synchronization clusters in spatially extended dynamical systems},
  series = {Physical Review E},
  volume    = {74},
  journal   = {Physical Review E},
  number    = {5},
  issn      = {2470-0053},
  doi       = {10.1103/PhysRevE.74.051909},
  pages     = {051909},
  year      = {2006},
  language  = {en}
}
@article{LehnertzMormannOsterhageetal.2007,
  author    = {Lehnertz, Klaus and Mormann, Florian and Osterhage, Hannes and Andy, M{\"u}ller and Prusseit, Jens and Chernihovskyi, Anton and Staniek, Matth{\"a}us and Krug, Dieter and Bialonski, Stephan and Elger, Christian E.},
  title     = {State-of-the-art of seizure prediction},
  series = {Journal of Clinical Neurophysiology},
  volume    = {24},
  journal   = {Journal of Clinical Neurophysiology},
  number    = {2},
  issn      = {1537-1603},
  doi       = {10.1097/WNP.0b013e3180336f16},
  pages     = {147 -- 153},
  year      = {2007},
  language  = {en}
}
@article{AllefeldBialonski2007,
  author    = {Allefeld, Carsten and Bialonski, Stephan},
  title     = {Detecting synchronization clusters in multivariate time series via coarse-graining of Markov chains},
  series = {Physical Review E},
  volume    = {76},
  journal   = {Physical Review E},
  number    = {6},
  issn      = {2470-0053},
  doi       = {10.1103/PhysRevE.76.066207},
  pages     = {066207},
  year      = {2007},
  language  = {en}
}
@article{BialonskiSchindlerElgeretal.2008,
  author    = {Bialonski, Stephan and Schindler, K. and Elger, C. E. and Lehnertz, Klaus},
  title     = {Lateralized characteristics of the evolution of EEG correlation during focal onset seizures: a mechanism to prevent secondary generalization?},
  series = {Epilepsia},
  volume    = {49},
  journal   = {Epilepsia},
  issn      = {0013-9580},
  pages     = {11 -- 11},
  year      = {2008},
  abstract  = {Rationale: Previous studies [Topolnik et al., Cereb Cortex 2003; 13: 883; Schindler et al., Brain 2007; 130: 65] indicate that the termination of focal onset seizures may be causally related to an increase of global neuronal correlation during the second half of the seizures. This increase was observed to occur earlier in complex partial seizures than in secondarily generalized seizures. We here address the question whether such an increase of neuronal correlation prior to seizure end is indeed a global phenomenon, involving both hemispheres or whether there are side-specific differences. Methods: We analyzed 20 focal onset seizures (10 complex partial, 10 secondarily generalized seizures) recorded in 13 patients who underwent presurgical evaluation of focal epilepsies of different origin. EEG was recorded intracranially from bilaterally implanted subdural strip and intrahippocampal depth electrodes. Utilizing a moving window approach, we investigated the evolution of the maximum cross correlation for all channel combinations during seizures. For each moving window the mean value of the maximum cross correlation (MCC) between all electrode contacts was computed separately for each hemisphere. After normalization of seizure durations, MCC values of the ipsi- and contralateral hemisphere for all seizures were determined. Results: We observed that the MCC of the contralateral hemisphere in complex partial seizures increased during the first half of the seizure, whereas, for the same time interval, the MCC of the ipsilateral hemisphere even declined below the level of the pre-seizure period. In contrast, no significant differences between both hemispheres could be observed for secondarily generalized seizures where both hemispheres showed a simultaneous increase of MCC during the second half of the seizures. The level of MCC for the contralateral hemisphere was higher for complex partial seizures than for secondarily generalized seizures during the first half of the seizure. Conclusions: Our findings indicate that there are indeed lateralized differences in the evolution of global neuronal correlation during complex partial and secondarily generalized seizures. The observed contralateral increase of neuronal correlation during complex partial seizures might indicate an emerging self-organizing mechanism for preventing the spread of seizure activity.},
  language  = {en}
}
@article{BialonskiAllefeldWellmeretal.2008,
  author    = {Bialonski, Stephan and Allefeld, C. and Wellmer, J. and Elger, C. and Lehnertz, K.},
  title     = {An approach to identify synchronization clusters within the epileptic network},
  series = {Klinische Neurophysiologie},
  volume    = {39},
  journal   = {Klinische Neurophysiologie},
  number    = {1},
  doi       = {10.1055/s-2008-1072881},
  pages     = {A79},
  year      = {2008},
  language  = {en}
}
@article{SchindlerBialonskiHorstmannetal.2008,
  author    = {Schindler, Kaspar A. and Bialonski, Stephan and Horstmann, Marie-Therese and Elger, Christian E. and Lehnertz, Klaus},
  title     = {Evolving functional network properties and synchronizability during human epileptic seizures},
  series = {Chaos: An Interdisciplinary Journal of Nonlinear Science},
  volume    = {18},
  journal   = {Chaos: An Interdisciplinary Journal of Nonlinear Science},
  number    = {3},
  issn      = {1089-7682},
  doi       = {10.1063/1.2966112},
  pages     = {033119},
  year      = {2008},
  language  = {en}
}
@incollection{OsterhageBialonskiStanieketal.2008,
  author    = {Osterhage, Hannes and Bialonski, Stephan and Staniek, Matth{\"a}us and Schindler, Kaspar and Wagner, Tobias and Elger, Christian E. and Lehnertz, Klaus},
  title     = {Bivariate and multivariate time series analysis techniques and their potential impact for seizure prediction},
  series = {Seizure Prediction in Epilepsy: From Basic Mechanisms to Clinical Applications},
  booktitle = {Seizure Prediction in Epilepsy: From Basic Mechanisms to Clinical Applications},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  isbn      = {978-3-527-62519-2},
  doi       = {10.1002/9783527625192.ch15},
  pages     = {189 -- 208},
  year      = {2008},
  language  = {en}
}
@article{LehnertzBialonskiHorstmannetal.2009,
  author    = {Lehnertz, Klaus and Bialonski, Stephan and Horstmann, Marie-Therese and Krug, Dieter and Rothkegel, Alexander and Staniek, Matth{\"a}us and Wagner, Tobias},
  title     = {Synchronization phenomena in human epileptic brain networks},
  series = {Journal of neuroscience methods},
  volume    = {183},
  journal   = {Journal of neuroscience methods},
  number    = {1},
  issn      = {0165-0270},
  doi       = {10.1016/j.jneumeth.2009.05.015},
  pages     = {42 -- 48},
  year      = {2009},
  language  = {en}
}
@incollection{LehnertzBialonskiHorstmannetal.2010,
  author    = {Lehnertz, Klaus and Bialonski, Stephan and Horstmann, Marie-Therese and Krug, Dieter and Rothkegel, Alexander and Staniek, Matth{\"a}us and Wagner, Tobias},
  title     = {Epilepsy},
  series = {Reviews of Nonlinear Dynamics and Complexity, Volume 2},
  booktitle = {Reviews of Nonlinear Dynamics and Complexity, Volume 2},
  publisher = {Wiley-VCH},
  isbn      = {9783527628001},
  doi       = {10.1002/9783527628001.ch5},
  pages     = {159 -- 200},
  year      = {2010},
  language  = {en}
}
@article{HorstmannBialonskiNoenningetal.2010,
  author    = {Horstmann, Marie-Therese and Bialonski, Stephan and Noenning, Nina and Mai, Heinke and Prusseit, Jens and Wellmer, J{\"o}rg and Hinrichs, Hermann and Lehnertz, Klaus},
  title     = {State dependent properties of epileptic brain networks: Comparative graph-theoretical analyses of simultaneously recorded EEG and MEG},
  series = {Clinical Neurophysiology},
  volume    = {121},
  journal   = {Clinical Neurophysiology},
  number    = {2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1388-2457},
  doi       = {10.1016/j.clinph.2009.10.013},
  pages     = {172 -- 185},
  year      = {2010},
  abstract  = {Objective To investigate whether functional brain networks of epilepsy patients treated with antiepileptic medication differ from networks of healthy controls even during the seizure-free interval. Methods We applied different rules to construct binary and weighted networks from EEG and MEG data recorded under a resting-state eyes-open and eyes-closed condition from 21 epilepsy patients and 23 healthy controls. The average shortest path length and the clustering coefficient served as global statistical network characteristics. Results Independent on the behavioral condition, epileptic brains exhibited a more regular functional network structure. Similarly, the eyes-closed condition was characterized by a more regular functional network structure in both groups. The amount of network reorganization due to behavioral state changes was similar in both groups. Consistent findings could be achieved for networks derived from EEG but hardly from MEG recordings, and network construction rules had a rather strong impact on our findings. Conclusions Despite the locality of the investigated processes epileptic brain networks differ in their global characteristics from non-epileptic brain networks. Further methodological developments are necessary to improve the characterization of disturbed and normal functional networks. Significance An increased regularity and a diminished modulation capability appear characteristic of epileptic brain networks.},
  language  = {en}
}
@article{BialonskiHorstmannLehnertz2010,
  author    = {Bialonski, Stephan and Horstmann, Marie-Therese and Lehnertz, Klaus},
  title     = {From brain to earth and climate systems: Small-world interaction networks or not?},
  series = {Chaos: An Interdisciplinary Journal of Nonlinear Science},
  volume    = {20},
  journal   = {Chaos: An Interdisciplinary Journal of Nonlinear Science},
  number    = {1},
  publisher = {AIP Publishing},
  address   = {Melville, NY},
  issn      = {1089-7682},
  doi       = {10.1063/1.3360561},
  pages     = {013134},
  year      = {2010},
  abstract  = {We consider recent reports on small-world topologies of interaction networks derived from the dynamics of spatially extended systems that are investigated in diverse scientific fields such as neurosciences, geophysics, or meteorology. With numerical simulations that mimic typical experimental situations, we have identified an important constraint when characterizing such networks: indications of a small-world topology can be expected solely due to the spatial sampling of the system along with the commonly used time series analysis based approaches to network characterization.},
  language  = {en}
}
@incollection{Bialonski2016,
  author    = {Bialonski, Stephan},
  title     = {Are interaction clusters in epileptic networks predictive of seizures?},
  series = {Epilepsy: The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics},
  booktitle = {Epilepsy: The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics},
  publisher = {CRC Press},
  isbn      = {978-143983886-0},
  pages     = {349 -- 355},
  year      = {2016},
  language  = {en}
}
@article{BialonskiWendlerLehnertz2011,
  author    = {Bialonski, Stephan and Wendler, Martin and Lehnertz, Klaus},
  title     = {Unraveling spurious properties of interaction networks with tailored random networks},
  series = {Plos one},
  volume    = {6},
  journal   = {Plos one},
  number    = {8},
  publisher = {Plos},
  address   = {San Francisco},
  doi       = {10.1371/journal.pone.0022826},
  pages     = {e22826},
  year      = {2011},
  abstract  = {We investigate interaction networks that we derive from multivariate time series with methods frequently employed in diverse scientific fields such as biology, quantitative finance, physics, earth and climate sciences, and the neurosciences. Mimicking experimental situations, we generate time series with finite length and varying frequency content but from independent stochastic processes. Using the correlation coefficient and the maximum cross-correlation, we estimate interdependencies between these time series. With clustering coefficient and average shortest path length, we observe unweighted interaction networks, derived via thresholding the values of interdependence, to possess non-trivial topologies as compared to Erd{\"o}s-R{\´e}nyi networks, which would indicate small-world characteristics. These topologies reflect the mostly unavoidable finiteness of the data, which limits the reliability of typically used estimators of signal interdependence. We propose random networks that are tailored to the way interaction networks are derived from empirical data. Through an exemplary investigation of multichannel electroencephalographic recordings of epileptic seizures - known for their complex spatial and temporal dynamics - we show that such random networks help to distinguish network properties of interdependence structures related to seizure dynamics from those spuriously induced by the applied methods of analysis.},
  language  = {en}
}
@book{Bialonski2012,
  author    = {Bialonski, Stephan},
  title     = {Inferring complex networks from time series of dynamical systems: Pitfalls, misinterpretations, and possible solutions},
  publisher = {Universit{\"a}ts- und Landesbibliothek Bonn},
  address   = {Bonn},
  pages     = {Online-Ausgabe (III, 135 S. : Ill., graph. Darst.)},
  year      = {2012},
  language  = {en}
}
@incollection{BialonskiLehnertz2013,
  author    = {Bialonski, Stephan and Lehnertz, Klaus},
  title     = {From time series to complex networks: an overview},
  series = {Recent Advances in Predicting and Preventing Epileptic Seizures: Proceedings of the 5th International Workshop on Seizure Prediction},
  booktitle = {Recent Advances in Predicting and Preventing Epileptic Seizures: Proceedings of the 5th International Workshop on Seizure Prediction},
  isbn      = {978-981-4525-36-7},
  doi       = {10.1142/9789814525350_0010},
  pages     = {132 -- 147},
  year      = {2013},
  abstract  = {The network approach towards the analysis of the dynamics of complex systems has been successfully applied in a multitude of studies in the neurosciences and has yielded fascinating insights. With this approach, a complex system is considered to be composed of different constituents which interact with each other. Interaction structures can be compactly represented in interaction networks. In this contribution, we present a brief overview about how interaction networks are derived from multivariate time series, about basic network characteristics, and about challenges associated with this analysis approach.},
  language  = {en}
}
@article{BialonskiLehnertz2013,
  author    = {Bialonski, Stephan and Lehnertz, Klaus},
  title     = {Assortative mixing in functional brain networks during epileptic seizures},
  series = {Chaos: An Interdisciplinary Journal of Nonlinear Science},
  volume    = {23},
  journal   = {Chaos: An Interdisciplinary Journal of Nonlinear Science},
  number    = {3},
  doi       = {10.1063/1.4821915},
  pages     = {033139},
  year      = {2013},
  language  = {en}
}
@article{KuhnertBialonskiNoenningetal.2013,
  author    = {Kuhnert, Marie-Therese and Bialonski, Stephan and Noenning, Nina and Mai, Heinke and Hinrichs, Hermann and Helmstaedter, Christoph and Lehnertz, Klaus},
  title     = {Incidental and intentional learning of verbal episodic material differentially modifies functional brain networks},
  series = {Plos one},
  volume    = {8},
  journal   = {Plos one},
  number    = {11},
  publisher = {PLOS},
  address   = {San Francisco},
  doi       = {10.1371/journal.pone.0080273},
  pages     = {e80273},
  year      = {2013},
  abstract  = {Learning- and memory-related processes are thought to result from dynamic interactions in large-scale brain networks that include lateral and mesial structures of the temporal lobes. We investigate the impact of incidental and intentional learning of verbal episodic material on functional brain networks that we derive from scalp-EEG recorded continuously from 33 subjects during a neuropsychological test schedule. Analyzing the networks' global statistical properties we observe that intentional but not incidental learning leads to a significantly increased clustering coefficient, and the average shortest path length remains unaffected. Moreover, network modifications correlate with subsequent recall performance: the more pronounced the modifications of the clustering coefficient, the higher the recall performance. Our findings provide novel insights into the relationship between topological aspects of functional brain networks and higher cognitive functions.},
  language  = {en}
}
@article{LehnertzAnsmannBialonskietal.2014,
  author    = {Lehnertz, Klaus and Ansmann, Gerrit and Bialonski, Stephan and Dickten, Henning and Geier, Christian and Porz, Stephan},
  title     = {Evolving networks in the human epileptic brain},
  series = {Physica D: Nonlinear Phenomena},
  volume    = {267},
  journal   = {Physica D: Nonlinear Phenomena},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0167-2789},
  doi       = {10.1016/j.physd.2013.06.009},
  pages     = {7 -- 15},
  year      = {2014},
  abstract  = {Network theory provides novel concepts that promise an improved characterization of interacting dynamical systems. Within this framework, evolving networks can be considered as being composed of nodes, representing systems, and of time-varying edges, representing interactions between these systems. This approach is highly attractive to further our understanding of the physiological and pathophysiological dynamics in human brain networks. Indeed, there is growing evidence that the epileptic process can be regarded as a large-scale network phenomenon. We here review methodologies for inferring networks from empirical time series and for a characterization of these evolving networks. We summarize recent findings derived from studies that investigate human epileptic brain networks evolving on timescales ranging from few seconds to weeks. We point to possible pitfalls and open issues, and discuss future perspectives.},
  language  = {en}
}
@article{GeierBialonskiElgeretal.2015,
  author    = {Geier, Christian and Bialonski, Stephan and Elger, Christian E. and Lehnertz, Klaus},
  title     = {How important is the seizure onset zone for seizure dynamics?},
  series = {Seizure},
  volume    = {25},
  journal   = {Seizure},
  issn      = {1059-1311},
  doi       = {10.1016/j.seizure.2014.10.013},
  pages     = {160 -- 166},
  year      = {2015},
  language  = {en}
}
@article{GeierLehnertzBialonski2015,
  author    = {Geier, Christian and Lehnertz, Klaus and Bialonski, Stephan},
  title     = {Time-dependent degree-degree correlations in epileptic brain networks: from assortative to dissortative mixing},
  series = {Frontiers in Human Neuroscience},
  journal   = {Frontiers in Human Neuroscience},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1662-5161},
  doi       = {10.3389/fnhum.2015.00462},
  year      = {2015},
  language  = {en}
}
@article{MulhernBialonskiKantz2015,
  author    = {Mulhern, Colm and Bialonski, Stephan and Kantz, Holger},
  title     = {Extreme events due to localization of energy},
  series = {Physical Review E},
  volume    = {91},
  journal   = {Physical Review E},
  number    = {1},
  issn      = {2470-0053},
  doi       = {10.1103/PhysRevE.91.012918},
  pages     = {012918},
  year      = {2015},
  language  = {en}
}
@article{BialonskiAnsmannKantz2015,
  author    = {Bialonski, Stephan and Ansmann, Gerrit and Kantz, Holger},
  title     = {Data-driven prediction and prevention of extreme events in a spatially extended excitable system},
  series = {Physical Review E},
  volume    = {92},
  journal   = {Physical Review E},
  number    = {4},
  issn      = {2470-0053},
  doi       = {10.1103/PhysRevE.92.042910},
  pages     = {042910},
  year      = {2015},
  language  = {en}
}
@article{BialonskiCaronSchloenetal.2016,
  author    = {Bialonski, Stephan and Caron, David A. and Schloen, Julia and Feudel, Ulrike and Kantz, Holger and Moorthi, Stefanie D.},
  title     = {Phytoplankton dynamics in the Southern California Bight indicate a complex mixture of transport and biology},
  series = {Journal of Plankton Research},
  volume    = {38},
  journal   = {Journal of Plankton Research},
  number    = {4},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {1464-3774},
  doi       = {10.1093/plankt/fbv122},
  pages     = {1077 -- 1091},
  year      = {2016},
  abstract  = {The stimulation and dominance of potentially harmful phytoplankton taxa at a given locale and time are determined by local environmental conditions as well as by transport to or from neighboring regions. The present study investigated the occurrence of common harmful algal bloom (HAB) taxa within the Southern California Bight, using cross-correlation functions to determine potential dependencies between HAB taxa and environmental factors, and potential links to algal transport via local hydrography and currents. A simulation study, in which Lagrangian particles were released, was used to assess travel times due to advection by prevailing ocean currents in the bight. Our results indicate that transport of some taxa may be an important mechanism for the expansion of their distributions into other regions, which was supported by mean travel times derived from our simulation study and other literature on ocean currents in the Southern California Bight. In other cases, however, phytoplankton dynamics were rather linked to local environmental conditions, including coastal upwelling events. Overall, our study shows that complex current patterns in the Southern California Bight may contribute significantly to the formation and expansion of HABs in addition to local environmental factors determining the spatiotemporal dynamics of phytoplankton blooms.},
  language  = {en}
}
@article{NgamgaBialonskiMarwanetal.2016,
  author    = {Ngamga, Eulalie Joelle and Bialonski, Stephan and Marwan, Norbert and Kurths, J{\"u}rgen and Geier, Christian and Lehnertz, Klaus},
  title     = {Evaluation of selected recurrence measures in discriminating pre-ictal and inter-ictal periods from epileptic EEG data},
  series = {Physics Letters A},
  volume    = {380},
  journal   = {Physics Letters A},
  number    = {16},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0375-9601},
  doi       = {10.1016/j.physleta.2016.02.024},
  pages     = {1419 -- 1425},
  year      = {2016},
  abstract  = {We investigate the suitability of selected measures of complexity based on recurrence quantification analysis and recurrence networks for an identification of pre-seizure states in multi-day, multi-channel, invasive electroencephalographic recordings from five epilepsy patients. We employ several statistical techniques to avoid spurious findings due to various influencing factors and due to multiple comparisons and observe precursory structures in three patients. Our findings indicate a high congruence among measures in identifying seizure precursors and emphasize the current notion of seizure generation in large-scale epileptic networks. A final judgment of the suitability for field studies, however, requires evaluation on a larger database.},
  language  = {en}
}
@article{KarnatakKantzBialonski2017,
  author    = {Karnatak, Rajat and Kantz, Holger and Bialonski, Stephan},
  title     = {Early warning signal for interior crises in excitable systems},
  series = {Physical Review E},
  volume    = {96},
  journal   = {Physical Review E},
  number    = {4},
  issn      = {2470-0053},
  doi       = {10.1103/PhysRevE.96.042211},
  pages     = {042211},
  year      = {2017},
  language  = {en}
}
@article{SchwabedalSippelBrandtetal.2018,
  author    = {Schwabedal, Justus T. C. and Sippel, Daniel and Brandt, Moritz D. and Bialonski, Stephan},
  title     = {Automated Classification of Sleep Stages and EEG Artifacts in Mice with Deep Learning},
  doi       = {10.48550/arXiv.1809.08443},
  year      = {2018},
  abstract  = {Sleep scoring is a necessary and time-consuming task in sleep studies. In animal models (such as mice) or in humans, automating this tedious process promises to facilitate long-term studies and to promote sleep biology as a data-driven f ield. We introduce a deep neural network model that is able to predict different states of consciousness (Wake, Non-REM, REM) in mice from EEG and EMG recordings with excellent scoring results for out-of-sample data. Predictions are made on epochs of 4 seconds length, and epochs are classified as artifactfree or not. The model architecture draws on recent advances in deep learning and in convolutional neural networks research. In contrast to previous approaches towards automated sleep scoring, our model does not rely on manually defined features of the data but learns predictive features automatically. We expect deep learning models like ours to become widely applied in different fields, automating many repetitive cognitive tasks that were previously difficult to tackle.},
  language  = {en}
}
@article{BhattaraiStaat2018,
  author    = {Bhattarai, Aroj and Staat, Manfred},
  title     = {Computational comparison of different textile implants to correct apical prolapse in females},
  series = {Current Directions in Biomedical Engineering},
  volume    = {4},
  journal   = {Current Directions in Biomedical Engineering},
  number    = {1},
  publisher = {De Gruyter},
  address   = {Berlin},
  doi       = {10.1515/cdbme-2018-0159},
  pages     = {661 -- 664},
  year      = {2018},
  abstract  = {Prosthetic textile implants of different shapes, sizes and polymers are used to correct the apical prolapse after hysterectomy (removal of the uterus). The selection of the implant before or during minimally invasive surgery depends on the patient's anatomical defect, intended function after reconstruction and most importantly the surgeon's preference. Weakness or damage of the supporting tissues during childbirth, menopause or previous pelvic surgeries may put females in higher risk of prolapse. Numerical simulations of reconstructed pelvic floor with weakened tissues and organ supported by textile product models: DynaMesh®-PRS soft, DynaMesh®-PRP soft and DynaMesh®-CESA from FEG Textiletechnik mbH, Germany are compared.},
  language  = {en}
}
@article{HorbachStaat2018,
  author    = {Horbach, Andreas and Staat, Manfred},
  title     = {Optical strain measurement for the modeling of surgical meshes and their porosity},
  series = {Current Directions in Biomedical Engineering},
  volume    = {Band 4},
  journal   = {Current Directions in Biomedical Engineering},
  number    = {1},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {2364-5504},
  doi       = {10.1515/cdbme-2018-0045},
  pages     = {181 -- 184},
  year      = {2018},
  abstract  = {The porosity of surgical meshes makes them flexible for large elastic deformation and establishes the healing conditions of good tissue in growth. The biomechanic modeling of orthotropic and compressible materials requires new materials models and simulstaneoaus fit of deformation in the load direction as well as trannsversely to to load. This nonlinear modeling can be achieved by an optical deformation measurement. At the same time the full field deformation measurement allows the dermination of the change of porosity with deformation. Also the socalled effective porosity, which has been defined to asses the tisssue interatcion with the mesh implants, can be determined from the global deformation of the surgical meshes.},
  language  = {en}
}