@inproceedings{ZingsheimGrimmerOrtneretal.2019, author = {Zingsheim, Jonas and Grimmer, Timo and Ortner, Marion and Schmaderer, Christoph and Hauser, Christine and Kotliar, Konstantin}, title = {Recognition of subjects with mild cognitive impairment (MCI) by the use of retinal arterial vessels.}, series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen}, booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen}, editor = {Staat, Manfred and Erni, Daniel}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-22-6}, doi = {10.17185/duepublico/48750}, pages = {36 -- 37}, year = {2019}, language = {en} } @inproceedings{WaldmannVeraDachwaldetal.2018, author = {Waldmann, Christoph and Vera, Jean-Pierre de and Dachwald, Bernd and Strasdeit, Henry and Sohl, Frank and Hanff, Hendrik and Kowalski, Julia and Heinen, Dirk and Macht, Sabine and Bestmann, Ulf and Meckel, Sebastian and Hildebrandt, Marc and Funke, Oliver and Gehrt, Jan-J{\"o}ran}, title = {Search for life in ice-covered oceans and lakes beyond Earth}, series = {2018 IEEE/OES Autonomous Underwater Vehicle Workshop, Proceedings November 2018, Article number 8729761}, booktitle = {2018 IEEE/OES Autonomous Underwater Vehicle Workshop, Proceedings November 2018, Article number 8729761}, doi = {10.1109/AUV.2018.8729761}, year = {2018}, abstract = {The quest for life on other planets is closely connected with the search for water in liquid state. Recent discoveries of deep oceans on icy moons like Europa and Enceladus have spurred an intensive discussion about how these waters can be accessed. The challenge of this endeavor lies in the unforeseeable requirements on instrumental characteristics both with respect to the scientific and technical methods. The TRIPLE/nanoAUV initiative is aiming at developing a mission concept for exploring exo-oceans and demonstrating the achievements in an earth-analogue context, exploring the ocean under the ice shield of Antarctica and lakes like Dome-C on the Antarctic continent.}, language = {en} } @inproceedings{VoronkovaBauerKotliar2014, author = {Voronkova, Eva B. and Bauer, Svetlana M. and Kotliar, Konstantin}, title = {Computer simulation of the cornea-scleral shell as applied to pressure-volume relationship in the human eye}, series = {2014 International Conference on Computer Technologies in Physical and Engineering Applications : ICCTPEA 2014 : proceedings : June 30 2014-July 4 2014, St. Petersburg}, booktitle = {2014 International Conference on Computer Technologies in Physical and Engineering Applications : ICCTPEA 2014 : proceedings : June 30 2014-July 4 2014, St. Petersburg}, organization = {Institute of Electrical and Electronics Engineers}, isbn = {978-1-4799-5315-8}, pages = {204 -- 205}, year = {2014}, language = {en} } @inproceedings{TranStaatKreissig2007, author = {Tran, Thanh Ngoc and Staat, Manfred and Kreißig, R.}, title = {Calculation of load carrying capacity of shell structures with elasto-plastic material by direct methods}, year = {2007}, abstract = {Proceedings of the International Conference on Material Theory and Nonlinear Dynamics. MatDyn. Hanoi, Vietnam, Sept. 24-26, 2007, 8 p. In this paper, a method is introduced to determine the limit load of general shells using the finite element method. The method is based on an upper bound limit and shakedown analysis with elastic-perfectly plastic material model. A non-linear constrained optimisation problem is solved by using Newton's method in conjunction with a penalty method and the Lagrangean dual method. Numerical investigation of a pipe bend subjected to bending moments proves the effectiveness of the algorithm.}, subject = {Finite-Elemente-Methode}, language = {en} } @inproceedings{TranStaatKreissig2007, author = {Tran, Thanh Ngoc and Staat, Manfred and Kreißig, R.}, title = {Finite element shakedown and limit reliability analysis of thin shells}, year = {2007}, abstract = {A procedure for the evaluation of the failure probability of elastic-plastic thin shell structures is presented. The procedure involves a deterministic limit and shakedown analysis for each probabilistic iteration which is based on the kinematical approach and the use the exact Ilyushin yield surface. Based on a direct definition of the limit state function, the non-linear problems may be efficiently solved by using the First and Second Order Reliabiblity Methods (Form/SORM). This direct approach reduces considerably the necessary knowledge of uncertain technological input data, computing costs and the numerical error. In: Computational plasticity / ed. by Eugenio Onate. Dordrecht: Springer 2007. VII, 265 S. (Computational Methods in Applied Sciences ; 7) (COMPLAS IX. Part 1 . International Center for Numerical Methods in Engineering (CIMNE)). ISBN 978-1-402-06576-7 S. 186-189}, subject = {Finite-Elemente-Methode}, language = {en} } @inproceedings{TranStaat2012, author = {Tran, Thanh Ngoc and Staat, Manfred}, title = {A primal-dual shakedown analysis of 3D structures using the face-based smoothed finite element method}, series = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)}, booktitle = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)}, editor = {Eberhardsteiner, J.}, year = {2012}, language = {en} } @inproceedings{TranStaat2014, author = {Tran, Thanh Ngoc and Staat, Manfred}, title = {Uncertain multimode failure and limit analysis of shells}, series = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20-25, 2014, Barcelona}, booktitle = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20-25, 2014, Barcelona}, editor = {Onate, E.}, organization = {World Congress on Computational Mechanics <11, 2014, Barcelona>}, pages = {1 -- 12}, year = {2014}, language = {en} } @inproceedings{TranPhamStaat2008, author = {Tran, Thanh Ngoc and Pham, Phu Tinh and Staat, Manfred}, title = {Reliability analysis of shells based on direct plasticity methods}, year = {2008}, abstract = {Abstracts der CD-Rom Proceedings of the 8th World Congress on Computational Mechanics (WCCM8) and 5th Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008) 30.06. - 04.07.2008 Venedig, Italien. 2 Seiten Zusammenfassung der Autoren mit graph. Darst. und Literaturverzeichnis}, subject = {Finite-Elemente-Methode}, language = {en} } @inproceedings{TranNovacekTolbaetal.2011, author = {Tran, Thanh Ngoc and Novacek, V. and Tolba, R. and Klinge, U. and Turquier, F. and Staat, Manfred}, title = {Experimental and Computational approach to study colorectal anastomosis. ISB2011, Proceedings of the XXIII Congress of the International Society of Biomechanics, Brussels, Belgium, July 3-7, 2011}, year = {2011}, abstract = {Summary: This paper presents a methodology to study and understand the mechanics of stapled anastomotic behaviors by combining empirical experimentation and finite element analysis. Performance of stapled anastomosis is studied in terms of leakage and numerical results which are compared to in vitro experiments performed on fresh porcine tissue. Results suggest that leaks occur between the tissue and staple legs penetrating through the tissue.}, subject = {Anastomose}, language = {en} } @inproceedings{TranTrinhDaoetal.2022, author = {Tran, Ngoc Trinh and Trinh, Tu Luc and Dao, Ngoc Tien and Giap, Van Tan and Truong, Manh Khuyen and Dinh, Thuy Ha and Staat, Manfred}, title = {Limit and shakedown analysis of structures under random strength}, series = {Proceedings of (NACOME2022) The 11th National Conference on Mechanics, Vol. 1. Solid Mechanics, Rock Mechanics, Artificial Intelligence, Teaching and Training, Hanoi, December 2-3, 2022}, booktitle = {Proceedings of (NACOME2022) The 11th National Conference on Mechanics, Vol. 1. Solid Mechanics, Rock Mechanics, Artificial Intelligence, Teaching and Training, Hanoi, December 2-3, 2022}, publisher = {Nha xuat ban Khoa hoc tu nhien va Cong nghe (Verlag Naturwissenschaft und Technik)}, address = {Hanoi}, isbn = {978-604-357-084-7}, pages = {510 -- 518}, year = {2022}, abstract = {Direct methods comprising limit and shakedown analysis is a branch of computational mechanics. It plays a significant role in mechanical and civil engineering design. The concept of direct method aims to determinate the ultimate load bearing capacity of structures beyond the elastic range. For practical problems, the direct methods lead to nonlinear convex optimization problems with a large number of variables and onstraints. If strength and loading are random quantities, the problem of shakedown analysis is considered as stochastic programming. This paper presents a method so called chance constrained programming, an effective method of stochastic programming, to solve shakedown analysis problem under random condition of strength. In this our investigation, the loading is deterministic, the strength is distributed as normal or lognormal variables.}, language = {en} } @inproceedings{TranTranMatthiesetal.2016, author = {Tran, Ngoc Trinh and Tran, Thanh Ngoc and Matthies, Hermann G. and Stavroulakis, Georgios Eleftherios and Staat, Manfred}, title = {FEM Shakedown of uncertain structures by chance constrained programming}, series = {PAMM Proceedings in Applied Mathematics and Mechanics}, volume = {16}, booktitle = {PAMM Proceedings in Applied Mathematics and Mechanics}, number = {1}, issn = {1617-7061}, doi = {10.1002/pamm.201610346}, pages = {715 -- 716}, year = {2016}, language = {en} } @inproceedings{TranTranMatthiesetal.2016, author = {Tran, Ngoc Trinh and Tran, Thanh Ngoc and Matthies, H. G. and Stavroulakis, G. E. and Staat, Manfred}, title = {Shakedown analysis of plate bending analysis under stochastic uncertainty by chance constrained programming}, series = {ECCOMAS Congress 2016, VII European Congress on Computational Methods in Applied Sciences and Engineering. Crete Island, Greece, 5-10 June 2016}, booktitle = {ECCOMAS Congress 2016, VII European Congress on Computational Methods in Applied Sciences and Engineering. Crete Island, Greece, 5-10 June 2016}, editor = {Papadrakakis, M.}, pages = {13 S.}, year = {2016}, language = {en} } @inproceedings{TranStaatStavroulakis2014, author = {Tran, Ngoc Trinh and Staat, Manfred and Stavroulakis, G. E.}, title = {A multicriteria method for truss optimization}, series = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20-25, 2014, Barcelona}, booktitle = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20-25, 2014, Barcelona}, editor = {Onate, E.}, organization = {World Congress on Computational Mechanics <11, 2014, Barcelona>}, pages = {1 -- 12}, year = {2014}, language = {en} } @inproceedings{TranStaat2021, author = {Tran, Ngoc Trinh and Staat, Manfred}, title = {FEM shakedown analysis of Kirchhoff-Love plates under uncertainty of strength}, series = {Proceedings of UNCECOMP 2021}, booktitle = {Proceedings of UNCECOMP 2021}, isbn = {978-618-85072-6-5}, doi = {10.7712/120221.8041.19047}, pages = {323 -- 338}, year = {2021}, abstract = {A new formulation to calculate the shakedown limit load of Kirchhoff plates under stochastic conditions of strength is developed. Direct structural reliability design by chance con-strained programming is based on the prescribed failure probabilities, which is an effective approach of stochastic programming if it can be formulated as an equivalent deterministic optimization problem. We restrict uncertainty to strength, the loading is still deterministic. A new formulation is derived in case of random strength with lognormal distribution. Upper bound and lower bound shakedown load factors are calculated simultaneously by a dual algorithm.}, language = {en} } @inproceedings{TranMatthiesStavroulakisetal.2018, author = {Tran, Ngoc Trinh and Matthies, Hermann G. and Stavroulakis, Georgios Eleftherios and Staat, Manfred}, title = {Direct plastic structural design by chance constrained programming}, series = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, booktitle = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, pages = {12 Seiten}, year = {2018}, abstract = {We propose a stochastic programming method to analyse limit and shakedown of structures under random strength with lognormal distribution. In this investigation a dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit or the shakedown limit. The edge-based smoothed finite element method (ES-FEM) using three-node linear triangular elements is used.}, language = {en} } @inproceedings{Tepecik2024, author = {Tepecik, Atakan}, title = {AstroBioLab: Review of technical and bioanalytical approaches}, series = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen}, booktitle = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen}, editor = {Digel, Ilya and Staat, Manfred and Trzewik, J{\"u}rgen and Sielemann, Stefanie and Erni, Daniel and Zylka, Waldemar}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-65-3}, doi = {10.17185/duepublico/81475}, pages = {33 -- 34}, year = {2024}, abstract = {This study presents the concept of AstroBioLab, an autonomous astrobiological field laboratory tailored for the exploration of (sub)glacial habitats. AstroBioLab is an integral component of the TRIPLE (Technologies for Rapid Ice Penetration and subglacial Lake Exploration) DLR-funded project, aimed at advancing astrobiology research through the development and deployment of innovative technologies. AstroBioLab integrates diverse measurement techniques such as fluorescence microscopy, DNA sequencing and fluorescence spectrometry, while leveraging microfluidics for efficient sample delivery and preparation.}, language = {en} } @inproceedings{SuryoputriGhaderiLinderetal.2017, author = {Suryoputri, Nathania and Ghaderi, Aydin and Linder, Peter and Kotliar, Konstantin and G{\"o}ttler, Jens and Sorg, Christian and Grimmer, Timo}, title = {Does hemodynamic response function change in Alzheimer disease?}, series = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, booktitle = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, editor = {Erni, Daniel and Fischerauer, Alice and Himmel, J{\"o}rg and Seeger, Thomas and Thelen, Klaus}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-9814801-9-1}, doi = {10.17185/duepublico/43984}, pages = {92}, year = {2017}, language = {en} } @inproceedings{StadlerEmbsZerlinetal.2007, author = {Stadler, Andreas M. and Embs, Jan P. and Zerlin, Kay and Digel, Ilya and Artmann, Gerhard and Zaccai, Joe and B{\"u}ldt, Georg}, title = {Temperature transitions of hemoglobin and cytosolic water diffusion in human red blood cells : [poster]}, year = {2007}, abstract = {Background Hemoglobin interactions in red blood cells Hemoglobin dynamics in human red blood cells Diffusion of H2O in red blood cells}, subject = {Erythrozyt}, language = {en} } @inproceedings{StaatTranPham2008, author = {Staat, Manfred and Tran, Thanh Ngoc and Pham, Phu Tinh}, title = {Limit and shakedown reliability analysis by nonlinear programming}, year = {2008}, abstract = {7th International Conference on Reliability of Materials and Structures (RELMAS 2008). June 17 - 20, 2008 ; Saint Petersburg, Russia. pp 354-358. Reprint with corrections in red Introduction Analysis of advanced structures working under extreme heavy loading such as nuclear power plants and piping system should take into account the randomness of loading, geometrical and material parameters. The existing reliability are restricted mostly to the elastic working regime, e.g. allowable local stresses. Development of the limit and shakedown reliability-based analysis and design methods, exploiting potential of the shakedown working regime, is highly needed. In this paper the application of a new algorithm of probabilistic limit and shakedown analysis for shell structures is presented, in which the loading and strength of the material as well as the thickness of the shell are considered as random variables. The reliability analysis problems may be efficiently solved by using a system combining the available FE codes, a deterministic limit and shakedown analysis, and the First and Second Order Reliability Methods (FORM/SORM). Non-linear sensitivity analyses are obtained directly from the solution of the deterministic problem without extra computational costs.}, subject = {Finite-Elemente-Methode}, language = {en} } @inproceedings{StaatTran2022, author = {Staat, Manfred and Tran, Ngoc Trinh}, title = {Strain based brittle failure criteria for rocks}, series = {Proceedings of (NACOME2022) The 11th National Conference on Mechanics, Vol. 1. Solid Mechanics, Rock Mechanics, Artificial Intelligence, Teaching and Training, Hanoi, December 2-3, 2022}, booktitle = {Proceedings of (NACOME2022) The 11th National Conference on Mechanics, Vol. 1. Solid Mechanics, Rock Mechanics, Artificial Intelligence, Teaching and Training, Hanoi, December 2-3, 2022}, publisher = {Nha xuat ban Khoa hoc tu nhien va Cong nghe (Verlag Naturwissenschaft und Technik)}, address = {Hanoi}, isbn = {978-604-357-084-7}, pages = {500 -- 509}, year = {2022}, abstract = {When confining pressure is low or absent, extensional fractures are typical, with fractures occurring on unloaded planes in rock. These "paradox" fractures can be explained by a phenomenological extension strain failure criterion. In the past, a simple empirical criterion for fracture initiation in brittle rock has been developed. But this criterion makes unrealistic strength predictions in biaxial compression and tension. A new extension strain criterion overcomes this limitation by adding a weighted principal shear component. The weight is chosen, such that the enriched extension strain criterion represents the same failure surface as the Mohr-Coulomb (MC) criterion. Thus, the MC criterion has been derived as an extension strain criterion predicting failure modes, which are unexpected in the understanding of the failure of cohesive-frictional materials. In progressive damage of rock, the most likely fracture direction is orthogonal to the maximum extension strain. The enriched extension strain criterion is proposed as a threshold surface for crack initiation CI and crack damage CD and as a failure surface at peak P. Examples show that the enriched extension strain criterion predicts much lower volumes of damaged rock mass compared to the simple extension strain criterion.}, language = {en} } @inproceedings{StaatHeitzer2002, author = {Staat, Manfred and Heitzer, Michael}, title = {The restricted influence of kinematic hardening on shakedown loads}, year = {2002}, abstract = {Structural design analyses are conducted with the aim of verifying the exclusion of ratcheting. To this end it is important to make a clear distinction between the shakedown range and the ratcheting range. In cyclic plasticity more sophisticated hardening models have been suggested in order to model the strain evolution observed in ratcheting experiments. The hardening models used in shakedown analysis are comparatively simple. It is shown that shakedown analysis can make quite stable predictions of admissible load ranges despite the simplicity of the underlying hardening models. A linear and a nonlinear kinematic hardening model of two-surface plasticity are compared in material shakedown analysis. Both give identical or similar shakedown ranges. Structural shakedown analyses show that the loading may have a more pronounced effect than the hardening model.}, subject = {Biomedizinische Technik}, language = {en} } @inproceedings{StaatDuong2016, author = {Staat, Manfred and Duong, Minh Tuan}, title = {Smoothed Finite Element Methods for Nonlinear Solid Mechanics Problems: 2D and 3D Case Studies}, series = {Proceedings of the National Science and Technology Conference on Mechanical - Transportation Engineering (NSCMET 2016), 13th October 2016, Hanoi, Vietnam, Vol.2}, booktitle = {Proceedings of the National Science and Technology Conference on Mechanical - Transportation Engineering (NSCMET 2016), 13th October 2016, Hanoi, Vietnam, Vol.2}, pages = {440 -- 445}, year = {2016}, abstract = {The Smoothed Finite Element Method (SFEM) is presented as an edge-based and a facebased techniques for 2D and 3D boundary value problems, respectively. SFEMs avoid shortcomings of the standard Finite Element Method (FEM) with lower order elements such as overly stiff behavior, poor stress solution, and locking effects. Based on the idea of averaging spatially the standard strain field of the FEM over so-called smoothing domains SFEM calculates the stiffness matrix for the same number of degrees of freedom (DOFs) as those of the FEM. However, the SFEMs significantly improve accuracy and convergence even for distorted meshes and/or nearly incompressible materials. Numerical results of the SFEMs for a cardiac tissue membrane (thin plate inflation) and an artery (tension of 3D tube) show clearly their advantageous properties in improving accuracy particularly for the distorted meshes and avoiding shear locking effects.}, language = {en} } @inproceedings{Staat2003, author = {Staat, Manfred}, title = {Design by Analysis of Pressure Components by non-linear Optimization}, year = {2003}, abstract = {This paper presents the direct route to Design by Analysis (DBA) of the new European pressure vessel standard in the language of limit and shakedown analysis (LISA). This approach leads to an optimization problem. Its solution with Finite Element Analysis is demonstrated for some examples from the DBA-Manual. One observation from the examples is, that the optimisation approach gives reliable and close lower bound solutions leading to simple and optimised design decision.}, language = {en} } @inproceedings{Staat2006, author = {Staat, Manfred}, title = {Problems and chances for probabilistic fracture mechanics in the analysis of steel pressure boundary reliability. - {\"U}berarb. Ausg.}, year = {2006}, abstract = {In: Technical feasibility and reliability of passive safety systems for nuclear power plants. Proceedings of an Advisory Group Meeting held in J{\"u}lich, 21-24 November 1994. - Vienna , 1996. - Seite: 43 - 55 IAEA-TECDOC-920 Abstract: It is shown that the difficulty for probabilistic fracture mechanics (PFM) is the general problem of the high reliability of a small population. There is no way around the problem as yet. Therefore what PFM can contribute to the reliability of steel pressure boundaries is demon­strated with the example of a typical reactor pressure vessel and critically discussed. Although no method is distinguishable that could give exact failure probabilities, PFM has several addi­tional chances. Upper limits for failure probability may be obtained together with trends for design and operating conditions. Further, PFM can identify the most sensitive parameters, improved control of which would increase reliability. Thus PFM should play a vital role in the analysis of steel pressure boundaries despite all shortcomings.}, subject = {Bruchmechanik}, language = {en} } @inproceedings{SpurmannOhndorfDachwaldetal.2009, author = {Spurmann, J{\"o}rn and Ohndorf, Andreas and Dachwald, Bernd and Seboldt, Wolfgang and L{\"o}b, Horst and Schartner, Karl-Heinz}, title = {Interplanetary trajectory optimization for a sep mission to Saturn}, series = {60th International Astronautical Congress 2009}, booktitle = {60th International Astronautical Congress 2009}, isbn = {9781615679089}, pages = {5234 -- 5248}, year = {2009}, abstract = {The recently proposed NASA and ESA missions to Saturn and Jupiter pose difficult tasks to mission designers because chemical propulsion scenarios are not capable of transferring heavy spacecraft into the outer solar system without the use of gravity assists. Thus our developed mission scenario based on the joint NASA/ESA Titan Saturn System Mission baselines solar electric propulsion to improve mission flexibility and transfer time. For the calculation of near-globally optimal low-thrust trajectories, we have used a method called Evolutionary Neurocontrol, which is implemented in the low-thrust trajectory optimization software InTrance. The studied solar electric propulsion scenario covers trajectory optimization of the interplanetary transfer including variations of the spacecraft's thrust level, the thrust unit's specific impulse and the solar power generator power level. Additionally developed software extensions enabled trajectory optimization with launcher-provided hyperbolic excess energy, a complex solar power generator model and a variable specific impulse ion engine model. For the investigated mission scenario, Evolutionary Neurocontrol yields good optimization results, which also hold valid for the more elaborate spacecraft models. Compared to Cassini/Huygens, the best found solutions have faster transfer times and a higher mission flexibility in general.}, language = {en} } @inproceedings{SherelkhanAlibekova2024, author = {Sherelkhan, Dinara and Alibekova, Alina}, title = {EEM spectroscopy characterization of humic substances of biomedical importance}, series = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen}, booktitle = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen}, editor = {Digel, Ilya and Staat, Manfred and Trzewik, J{\"u}rgen and Sielemann, Stefanie and Erni, Daniel and Zylka, Waldemar}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-65-3}, doi = {10.17185/duepublico/81475}, pages = {31 -- 32}, year = {2024}, abstract = {Humic substances possess distinctive chemical features enabling their use in many advanced applications, including biomedical fields. No chemicals in nature have the same combination of specific chemical and biological properties as humic substances. Traditional medicine and modern research have demonstrated that humic substances from different sources possess immunomodulatory and anti-inflammatory properties, which makes them suitable for the prevention and treatment of chronic dermatoses, allergic rhinitis, atopic dermatitis, and other conditions characterized by inflammatory and allergic responses [1-4]. The use of humic compounds as agentswith antifungal and antiviral properties shows great potential [5-7].}, language = {en} } @inproceedings{SeefeldtBauerDachwaldetal.2015, author = {Seefeldt, Patric and Bauer, Waldemar and Dachwald, Bernd and Grundmann, Jan Thimo and Straubel, Marco and Sznajder, Maciej and T{\´o}th, Norbert and Zander, Martin E.}, title = {Large lightweight deployable structures for planetary defence: solar sail propulsion, solar concentrator payloads, large-scale photovoltaic power}, series = {4th IAA Planetary Defense Conference - PDC 2015, 13-17 April 2015, Frascati, Roma, Italy}, booktitle = {4th IAA Planetary Defense Conference - PDC 2015, 13-17 April 2015, Frascati, Roma, Italy}, pages = {24}, year = {2015}, language = {en} } @inproceedings{SeboldtDachwald2003, author = {Seboldt, Wolfgang and Dachwald, Bernd}, title = {Solar sails for near-term advanced scientific deep space missions}, series = {Proceedings of the 8th International Workshop on Combustion and Propulsion}, booktitle = {Proceedings of the 8th International Workshop on Combustion and Propulsion}, pages = {14 Seiten}, year = {2003}, abstract = {Solar sails are propelled in space by reflecting solar photons off large mirroring surfaces, thereby transforming the momentum of the photons into a propulsive force. This innovative concept for low-thrust space propulsion works without any propellant and thus provides a wide range of opportunities for highenergy low-cost missions. Offering an efficient way of propulsion, solar sailcraft could close a gap in transportation options for highly demanding exploration missions within our solar system and even beyond. On December 17th, 1999, a significant step was made towards the realization of this technology: a lightweight solar sail structure with an area of 20 m × 20 m was successfully deployed on ground in a large facility at the German Aerospace Center (DLR) at Cologne. The deployment from a package of 60 cm × 60 cm × 65 cm with a total mass of less than 35 kg was achieved using four extremely light-weight carbon fiber reinforced plastics (CFRP) booms with a specific mass of 100 g/m. The paper briefly reviews the basic principles of solar sails as well as the technical concept and its realization in the ground demonstration experiment, performed in close cooperation between DLR and ESA. Next possible steps are outlined. They could comprise the in-orbit demonstration of the sail deployment on the upper stage of a low-cost rocket and the verification of the propulsion concept by an autonomous and free flying solar sail in the frame of a scientific mission. It is expected that the present design could be extended to sail sizes of about (40 m)2 up to even (70 m)2 without significant mass penalty. With these areas, the maximum achievable thrust at 1 AU would range between 10 and 40 mN - comparable to some electric thrusters. Such prototype sails with a mass between 50 and 150 kg plus a micro-spacecraft of 50 to 250 kg would have a maximum acceleration in the order of 0.1 mm/s2 at 1 AU, corresponding to a maximum ∆V-capability of about 3 km/s per year. Two near/medium-term mission examples to a near-Earth asteroid (NEA) will be discussed: a rendezvous mission and a sample return mission.}, language = {en} } @inproceedings{SeboldtBlomeDachwaldetal.2004, author = {Seboldt, Wolfgang and Blome, Hans-Joachim and Dachwald, Bernd and Richter, Lutz}, title = {Proposal for an integrated European space exploration strategy}, series = {55th International Astronautical Congress of the International Astronautical Federation, the International Academy of Astronautics, and the International Institute of Space Law}, booktitle = {55th International Astronautical Congress of the International Astronautical Federation, the International Academy of Astronautics, and the International Institute of Space Law}, pages = {1 -- 10}, year = {2004}, abstract = {Recently, in his vision for space exploration, US president Bush announced to extend human presence across the solar system, starting with a human return to the Moon as early as 2015 in preparation for human exploration of Mars and other destinations. In Europe, an exploration program, termed AURORA, was established by ESA in 2001 - funded on a voluntary basis by ESA member states - with a clear focus on Mars and the ultimate goal of landing humans on Mars around 2030 in international cooperation. In 2003, a Human Spaceflight Vision Group was appointed by ESA with the task to develop a vision for the role of human spaceflight during the next quarter of the century. The resulting vision focused on a European-led lunar exploration initiative as part of a multi-decade, international effort to strengthen European identity and economy. After a review of the situation in Europe concerning space exploration, the paper outlines an approach for a consistent positioning of exploration within the existing European space programs, identifies destinations, and develops corresponding scenarios for an integrated strategy, starting with robotic missions to the Moon, Mars, and near-Earth asteroids. The interests of the European planetary in-situ science community, which recently met at DLR Cologne, are considered. Potential robotic lunar missions comprise polar landings to search for frozen volatiles and a sample return. For Mars, the implementation of a modest robotic landing mission in 2009 to demonstrate the capability for landing and prepare more ambitious and complex missions is discussed. For near-Earth asteroid exploration, a low-cost in-situ technology demonstration mission could yield important results. All proposed scenarios offer excellent science and could therefore create synergies between ESA's mandatory and optional programs in the area of planetary science and exploration. The paper intents to stimulate the European discussion on space exploration and reflects the personal view of the authors.}, language = {en} } @inproceedings{SchoutetensDachwaldHeiligers2021, author = {Schoutetens, Frederic and Dachwald, Bernd and Heiligers, Jeannette}, title = {Optimisation of photon-sail trajectories in the alpha-centauri system using evolutionary neurocontrol}, series = {8th ICATT (International Conference on Astrodynamics Tools and Techniques) 23 - 25 June 2021, Virtual}, booktitle = {8th ICATT (International Conference on Astrodynamics Tools and Techniques) 23 - 25 June 2021, Virtual}, pages = {1 -- 15}, year = {2021}, abstract = {With the increased interest for interstellar exploration after the discovery of exoplanets and the proposal by Breakthrough Starshot, this paper investigates the optimisation of photon-sail trajectories in Alpha Centauri. The prime objective is to find the optimal steering strategy for a photonic sail to get captured around one of the stars after a minimum-time transfer from Earth. By extending the idea of the Breakthrough Starshot project with a deceleration phase upon arrival, the mission's scientific yield will be increased. As a secondary objective, transfer trajectories between the stars and orbit-raising manoeuvres to explore the habitable zones of the stars are investigated. All trajectories are optimised for minimum time of flight using the trajectory optimisation software InTrance. Depending on the sail technology, interstellar travel times of 77.6-18,790 years can be achieved, which presents an average improvement of 30\% with respect to previous work. Still, significant technological development is required to reach and be captured in the Alpha-Centauri system in less than a century. Therefore, a fly-through mission arguably remains the only option for a first exploratory mission to Alpha Centauri, but the enticing results obtained in this work provide perspective for future long-residence missions to our closest neighbouring star system.}, language = {en} } @inproceedings{SchneiderAlHakimKayseretal.2017, author = {Schneider, Oliver and Al Hakim, Taher and Kayser, Peter and Digel, Ilya}, title = {Development and trials of a test chamber for ultrasound-assisted sampling of living cells from solid surfaces}, series = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, booktitle = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, editor = {Erni, Daniel and Fischerauer, Alice and Himmel, J{\"o}rg and Seeger, Thomas and Thelen, Klaus}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-9814801-9-1}, doi = {10.17185/duepublico/43984}, pages = {96 -- 97}, year = {2017}, language = {en} } @inproceedings{SchmitzApandiSpillneretal.2024, author = {Schmitz, Annika and Apandi, Shah Eiman Amzar Shah and Spillner, Jan and Hima, Flutura and Behbahani, Mehdi}, title = {Effect of different cannula positions in the pulmonary artery on blood flow and gas exchange using computational fluid dynamics analysis}, series = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen}, booktitle = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen}, editor = {Digel, Ilya and Staat, Manfred and Trzewik, J{\"u}rgen and Sielemann, Stefanie and Erni, Daniel and Zylka, Waldemar}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-65-3}, doi = {10.17185/duepublico/81475}, pages = {29 -- 30}, year = {2024}, abstract = {Pulmonary arterial cannulation is a common and effective method for percutaneous mechanical circulatory support for concurrent right heart and respiratory failure [1]. However, limited data exists to what effect the positioning of the cannula has on the oxygen perfusion throughout the pulmonary artery (PA). This study aims to evaluate, using computational fluid dynamics (CFD), the effect of different cannula positions in the PA with respect to the oxygenation of the different branching vessels in order for an optimal cannula position to be determined. The four chosen different positions (see Fig. 1) of the cannulas are, in the lower part of the main pulmonary artery (MPA), in the MPA at the junction between the right pulmonary artery (RPA) and the left pulmonary artery (LPA), in the RPA at the first branch of the RPA and in the LPA at the first branch of the LPA.}, language = {en} } @inproceedings{SchlemmerPorstBassametal.2017, author = {Schlemmer, Katharina and Porst, Dariusz and Bassam, Rasha and Artmann, Gerhard and Digel, Ilya}, title = {Effects of nitric oxide (NO) and ATP on red blood cell phenotype and deformability}, series = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, booktitle = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, editor = {Erni, Daniel and Fischerauer, Alice and Himmel, J{\"o}rg and Seeger, Thomas and Thelen, Klaus}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-9814801-9-1}, doi = {10.17185/duepublico/43984}, pages = {100 -- 101}, year = {2017}, language = {en} } @inproceedings{SchartnerLoebDachwaldetal.2009, author = {Schartner, Karl-Heinz and Loeb, H. W. and Dachwald, Bernd and Ohndorf, Andreas}, title = {Perspectives of electric propulsion for outer planetary and deep space missions}, series = {European Planetary Science Congress 2009}, booktitle = {European Planetary Science Congress 2009}, pages = {416 -- 416}, year = {2009}, abstract = {Solar-electric propulsion (SEP) is superior with respect to payload capacity, flight time and flexible launch window to the conventional interplanetary transfer method using chemical propulsion combined with gravity assists. This fact results from the large exhaust velocities of electric low-thrust propulsion and is favourable also for missions to the giant planets, Kuiper-belt objects and even for a heliopause probe (IHP) as shown in three studies by the authors funded by DLR. They dealt with a lander for Europa and a sample return mission from a mainbelt asteroid [1], with the TANDEM mission [2]; the third recent one investigates electric propulsion for the transfer to the edge of the solar system. All studies are based on triple-junction solar arrays, on rf-ion thrusters of the qualified RIT-22 type and they use the intelligent trajectory optimization program InTrance [3].}, language = {en} } @inproceedings{SavitskayaKistaubayevaAkimbekovetal.2013, author = {Savitskaya, Irina S. and Kistaubayeva, Aida S. and Akimbekov, Nuraly S. and Digel, Ilya and Zhubanova, Azhar A.}, title = {Performance of Bio-Composite Carbonized Materials in Probiotic Applications}, series = {World Academy of Science, Engineering and Technology International Journal of Biotechnology and Bioengineering}, volume = {7}, booktitle = {World Academy of Science, Engineering and Technology International Journal of Biotechnology and Bioengineering}, number = {7}, pages = {685 -- 689}, year = {2013}, language = {en} } @inproceedings{RichterBraunsteinStaeudleetal.2018, author = {Richter, Charlotte and Braunstein, Bjoern and St{\"a}udle, Benjamin and Attias, Julia and Suess, Alexander and Weber, T. and Rittweger, Joern and Green, David A. and Albracht, Kirsten}, title = {In vivo fascicle length of the gastrocnemius muscle during walking in simulated martian gravity using two different body weight support devices}, series = {23rd Annual Congress of the European College of Sport Science, Dublin, Irland}, booktitle = {23rd Annual Congress of the European College of Sport Science, Dublin, Irland}, year = {2018}, language = {en} } @inproceedings{RamanJungHorvathetal.2019, author = {Raman, Aravind Hariharan and Jung, Alexander and Horv{\´a}th, Andr{\´a}s and Becker, Nadine and Staat, Manfred}, title = {Modification of a computer model of human stem cell-derived cardiomyocyte electrophysiology based on Patch-Clamp measurements}, series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen}, booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen}, editor = {Staat, Manfred and Erni, Daniel}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-22-6}, doi = {10.17185/duepublico/48750}, pages = {10 -- 11}, year = {2019}, abstract = {Human induced pluripotent stem cells (hiPSCs) have shown to be promising in disease studies and drug screenings [1]. Cardiomyocytes derived from hiPSCs have been extensively investigated using patch-clamping and optical methods to compare their electromechanical behaviour relative to fully matured adult cells. Mathematical models can be used for translating findings on hiPSCCMs to adult cells [2] or to better understand the mechanisms of various ion channels when a drug is applied [3,4]. Paci et al. (2013) [3] developed the first model of hiPSC-CMs, which they later refined based on new data [3]. The model is based on iCells® (Fujifilm Cellular Dynamics, Inc. (FCDI), Madison WI, USA) but major differences among several cell lines and even within a single cell line have been found and motivate an approach for creating sample-specific models. We have developed an optimisation algorithm that parameterises the conductances (in S/F=Siemens/Farad) of the latest Paci et al. model (2018) [5] using current-voltage data obtained in individual patch-clamp experiments derived from an automated patch clamp system (Patchliner, Nanion Technologies GmbH, Munich).}, language = {en} } @inproceedings{PohleFroehlichDalitzRichteretal.2020, author = {Pohle-Fr{\"o}hlich, Regina and Dalitz, Christoph and Richter, Charlotte and Hahnen, Tobias and St{\"a}udle, Benjamin and Albracht, Kirsten}, title = {Estimation of muscle fascicle orientation in ultrasonic images}, series = {VISIGRAPP 2020 - Proceedings of the 15th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications, 5}, booktitle = {VISIGRAPP 2020 - Proceedings of the 15th International Joint Conference on Computer Vision, Imaging and Computer Graphics Theory and Applications, 5}, pages = {79 -- 86}, year = {2020}, language = {en} } @inproceedings{PirovanoSeefeldtDachwaldetal.2015, author = {Pirovano, Laura and Seefeldt, Patric and Dachwald, Bernd and Noomen, Ron}, title = {Attitude and Orbital Dynamics Modeling for an Uncontrolled Solar-Sail Experiment in Low-Earth Orbit}, series = {25th International Symposium on Spaceflight Dynamics, 2015, Munich, Germany}, booktitle = {25th International Symposium on Spaceflight Dynamics, 2015, Munich, Germany}, pages = {15 S.}, year = {2015}, language = {en} } @inproceedings{PirovanoSeefeldtDachwaldetal.2015, author = {Pirovano, Laura and Seefeldt, Patric and Dachwald, Bernd and Noomen, Ron}, title = {Attitude and orbital modeling of an uncontrolled solar-sail experiment in low-Earth orbit}, series = {25th International Symposium on Space Flight Dynamics ISSFD}, booktitle = {25th International Symposium on Space Flight Dynamics ISSFD}, pages = {1 -- 15}, year = {2015}, abstract = {Gossamer-1 is the first project of the three-step Gossamer roadmap, the purpose of which is to develop, prove and demonstrate that solar-sail technology is a safe and reliable propulsion technique for long-lasting and high-energy missions. This paper firstly presents the structural analysis performed on the sail to understand its elastic behavior. The results are then used in attitude and orbital simulations. The model considers the main forces and torques that a satellite experiences in low-Earth orbit coupled with the sail deformation. Doing the simulations for varying initial conditions in attitude and rotation rate, the results show initial states to avoid and maximum rotation rates reached for correct and faulty deployment of the sail. Lastly comparisons with the classic flat sail model are carried out to test the hypothesis that the elastic behavior does play a role in the attitude and orbital behavior of the sail}, language = {en} } @inproceedings{PhamStaat2015, author = {Pham, Phu Tinh and Staat, Manfred}, title = {A simplification for shakedown analysis of hardening structures}, series = {Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen , Germany, 20.07.2015 - 23.07.2015 / ed.: Stefanie Elgeti ; Jaan-Willem Simon}, booktitle = {Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen , Germany, 20.07.2015 - 23.07.2015 / ed.: Stefanie Elgeti ; Jaan-Willem Simon}, publisher = {RWTH Aachen University}, address = {Aachen}, organization = {ECCOMAS Young Investigators Conference <3, 2015, Aachen>}, pages = {1 -- 4}, year = {2015}, language = {en} } @inproceedings{PhamNguyenStaat2012, author = {Pham, Phu Tinh and Nguyen, Thanh Ngoc and Staat, Manfred}, title = {FEM based shakedown analysis of hardening structures}, series = {Proceedings International Conference on Advances in Computational Mechanics (ACOME)}, booktitle = {Proceedings International Conference on Advances in Computational Mechanics (ACOME)}, pages = {870 -- 882}, year = {2012}, language = {en} } @inproceedings{PeloniDachwaldCeriotti2017, author = {Peloni, Alessandro and Dachwald, Bernd and Ceriotti, Matteo}, title = {Multiple NEA rendezvous mission: Solar sailing options}, series = {Fourth International Symposium on Solar Sailing}, booktitle = {Fourth International Symposium on Solar Sailing}, pages = {1 -- 11}, year = {2017}, abstract = {The scientific interest in near-Earth asteroids (NEAs) and the classification of some of those as potentially hazardous asteroid for the Earth stipulated the interest in NEA exploration. Close-up observations of these objects will increase drastically our knowledge about the overall NEA population. For this reason, a multiple NEA rendezvous mission through solar sailing is investigated, taking advantage of the propellantless nature of this groundbreaking propulsion technology. Considering a spacecraft based on the DLR/ESA Gossamer technology, this work focuses on the search of possible sequences of NEA encounters. The effectiveness of this approach is demonstrated through a number of fully-optimized trajectories. The results show that it is possible to visit five NEAs within 10 years with near-term solar-sail technology. Moreover, a study on a reduced NEA database demonstrates the reliability of the approach used, showing that 58\% of the sequences found with an approximated trajectory model can be converted into real solar-sail trajectories. Lastly, this second study shows the effectiveness of the proposed automatic optimization algorithm, which is able to find solutions for a large number of mission scenarios without any input required from the user.}, language = {en} } @inproceedings{PeloniCeriottiDachwald2015, author = {Peloni, A. and Ceriotti, M. and Dachwald, Bernd}, title = {Preliminary trajectory design of a multiple NEO rendezvous mission through solar sailing}, series = {Proceedings of the International Astronautical Congress, IAC, Vol. 8, 2014}, booktitle = {Proceedings of the International Astronautical Congress, IAC, Vol. 8, 2014}, publisher = {Curran}, address = {Red Hook, NY}, isbn = {978-1-63439-986-9}, pages = {5352 -- 5366}, year = {2015}, language = {en} } @inproceedings{OhndorfDachwaldSeboldtetal.2011, author = {Ohndorf, Andreas and Dachwald, Bernd and Seboldt, Wolfgang and Schartner, Karl-Heinz}, title = {Flight times to the heliopause using a combination of solar and radioisotope electric propulsion}, series = {32nd International Electric Propulsion Conference}, booktitle = {32nd International Electric Propulsion Conference}, pages = {1 -- 12}, year = {2011}, abstract = {We investigate the interplanetary flight of a low-thrust space probe to the heliopause,located at a distance of about 200 AU from the Sun. Our goal was to reach this distance within the 25 years postulated by ESA for such a mission (which is less ambitious than the 15-year goal set by NASA). Contrary to solar sail concepts and combinations of allistic and electrically propelled flight legs, we have investigated whether the set flight time limit could also be kept with a combination of solar-electric propulsion and a second, RTG-powered upper stage. The used ion engine type was the RIT-22 for the first stage and the RIT-10 for the second stage. Trajectory optimization was carried out with the low-thrust optimization program InTrance, which implements the method of Evolutionary Neurocontrol,using Artificial Neural Networks for spacecraft steering and Evolutionary Algorithms to optimize the Neural Networks' parameter set. Based on a parameter space study, in which the number of thrust units, the unit's specific impulse, and the relative size of the solar power generator were varied, we have chosen one configuration as reference. The transfer time of this reference configuration was 29.6 years and the fastest one, which is technically more challenging, still required 28.3 years. As all flight times of this parameter study were longer than 25 years, we further shortened the transfer time by applying a launcher-provided hyperbolic excess energy up to 49 km2/s2. The resulting minimal flight time for the reference configuration was then 27.8 years. The following, more precise optimization to a launch with the European Ariane 5 ECA rocket reduced the transfer time to 27.5 years. This is the fastest mission design of our study that is flexible enough to allow a launch every year. The inclusion of a fly-by at Jupiter finally resulted in a flight time of 23.8 years,which is below the set transfer-time limit. However, compared to the 27.5-year transfer,this mission design has a significantly reduced launch window and mission flexibility if the escape direction is restricted to the heliosphere's "nose".}, language = {en} } @inproceedings{O'HerasDigelTemizArtmann2009, author = {O\'Heras, Carlos and Digel, Ilya and Temiz Artmann, Ayseg{\"u}l}, title = {Nanostructured carbon-based column for LPS/protein adsorption : [abstract]}, year = {2009}, abstract = {The absence of a general method for endotoxin removal from liquid interfaces gives an opportunity to find new methods and materials to overcome this gap. Activated nanostructured carbon is a promising material that showed good adsorption properties due to its vast pore network and high surface area. The aim of this study is to find the adsorption rates for a carboneous material produced at different temperatures, as well as to reveal possible differences between the performance of the material for each of the adsorbates used during the study (hemoglobin, serum albumin and lipopolysaccharide, LPS).}, subject = {Kohlenstofffaser}, language = {en} } @inproceedings{NixFrotscherStaat2012, author = {Nix, Yvonne and Frotscher, Ralf and Staat, Manfred}, title = {Implementation of the edge-based smoothed extended finite element method}, series = {Proceedings 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012) Vienna, Austria, September 10-14, 2012}, booktitle = {Proceedings 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012) Vienna, Austria, September 10-14, 2012}, editor = {Eberhardsteiner, J.}, year = {2012}, language = {en} } @inproceedings{MansurovZhubanovaDigeletal.2008, author = {Mansurov, Zulkhair and Zhubanova, Azhar A. and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Savitskaja, Irina S. and Kozhalakova, A. A. and Kistaubaeva, Aida S.}, title = {The sorption of LPS toxic shock by nanoparticles on base of carbonized vegetable raw materials}, year = {2008}, abstract = {Immobilization of lactobacillus on high temperature carbonizated vegetable raw material (rice husk, grape stones) increases their physiological activity and the quantity of the antibacterial metabolits, that consequently lead to increase of the antagonistic activity of lactobacillus. It is implies that the use of the nanosorbents for the attachment of the probiotical microorganisms are highly perspective for decision the important problems, such as the probiotical preparations delivery to the right address and their attachment to intestines mucosa with the following detoxication of gastro-intestinal tract and the normalization of it's microecology. Besides that, thus, the received carbonizated nanoparticles have peculiar properties - ability to sorption of LPS toxical shock and, hence, to the detoxication of LPS.}, subject = {Kohlenstofffaser}, language = {en} } @inproceedings{MandekarJentschLutzetal.2021, author = {Mandekar, Swati and Jentsch, Lina and Lutz, Kai and Behbahani, Mehdi and Melnykowycz, Mark}, title = {Earable design analysis for sleep EEG measurements}, series = {UbiComp '21}, booktitle = {UbiComp '21}, doi = {10.1145/3460418.3479328}, pages = {171 -- 175}, year = {2021}, abstract = {Conventional EEG devices cannot be used in everyday life and hence, past decade research has been focused on Ear-EEG for mobile, at-home monitoring for various applications ranging from emotion detection to sleep monitoring. As the area available for electrode contact in the ear is limited, the electrode size and location play a vital role for an Ear-EEG system. In this investigation, we present a quantitative study of ear-electrodes with two electrode sizes at different locations in a wet and dry configuration. Electrode impedance scales inversely with size and ranges from 450 kΩ to 1.29 MΩ for dry and from 22 kΩ to 42 kΩ for wet contact at 10 Hz. For any size, the location in the ear canal with the lowest impedance is ELE (Left Ear Superior), presumably due to increased contact pressure caused by the outer-ear anatomy. The results can be used to optimize signal pickup and SNR for specific applications. We demonstrate this by recording sleep spindles during sleep onset with high quality (5.27 μVrms).}, language = {en} } @inproceedings{LoebSchartnerDachwaldetal.2007, author = {Loeb, Horst Wolfgang and Schartner, Karl-Heinz and Dachwald, Bernd and Seboldt, Wolfgang}, title = {SEP-Sample return from a main belt asteroid}, series = {30th International Electric Propulsion Conference}, booktitle = {30th International Electric Propulsion Conference}, pages = {1 -- 11}, year = {2007}, abstract = {By DLR-contact, sample return missions to the large main-belt asteroid "19, Fortuna" have been studied. The mission scenario has been based on three ion thrusters of the RIT-22 model, which is presently under space qualification, and on solar arrays equipped with triple-junction GaAs solar cells. After having designed the spacecraft, the orbit-to-orbit trajectories for both, a one-way SEP mission with a chemical sample return and an all-SEP return mission, have been optimized using a combination of artificial neural networks with evolutionary algorithms. Additionally, body-to-body trajectories have been investigated within a launch period between 2012 and 2015. For orbit-to-orbit calculation, the launch masses of the hybrid mission and of the all-SEP mission resulted in 2.05 tons and 1.56 tons, respectively, including a scientific payload of 246 kg. For the related transfer durations 4.14 yrs and 4.62 yrs were obtained. Finally, a comparison between the mission scenarios based on SEP and on NEP have been carried out favouring clearly SEP.}, language = {en} } @inproceedings{LoebSchartnerSeboldtetal.2006, author = {Loeb, Horst W. and Schartner, Karl-Heinz and Seboldt, Wolfgang and Dachwald, Bernd and Streppel, Joern and Meusemann, Hans and Sch{\"u}lke, Peter}, title = {SEP for a lander mission to the jovian moon europa}, series = {57th International Astronautical Congress}, booktitle = {57th International Astronautical Congress}, doi = {10.2514/6.IAC-06-C4.4.04}, pages = {1 -- 12}, year = {2006}, abstract = {Under DLR-contract, Giessen University and DLR Cologne are studying solar-electric propulsion missions (SEP) to the outer regions of the solar system. The most challenging reference mission concerns the transport of a 1.35-tons chemical lander spacecraft into an 80-RJ circular orbit around Jupiter, which would enable to place a 375 kg lander with 50 kg of scientific instruments on the surface of the icy moon "Europa". Thorough analyses show that the best solution in terms of SEP launch mass times thrusting time would be a two-stage EP module and a triple-junction solar array with concentrators which would be deployed step by step. Mission performance optimizations suggest to propel the spacecraft in the first EP stage by 6 gridded ion thrusters, running at 4.0 kV of beam voltage, which would save launch mass, and in the second stage by 4 thrusters with 1.25 to 1.5 kV of positive high voltage saving thrusting time. In this way, the launch mass of the spacecraft would be kept within 5.3 tons. Without a launcher's C3 and interplanetary gravity assists, Jupiter might be reached within about 4 yrs. The spiraling-down into the parking orbit would need another 1.8 yrs. This "large mission" can be scaled down to a smaller one, e.g., by halving all masses, the solar array power, and the number of thrusters. Due to their reliability, long lifetime and easy control, RIT-22 engines have been chosen for mission analysis. Based on precise tests, the thruster performance has been modeled.}, language = {en} } @inproceedings{LoebSchartnerDachwaldetal.2011, author = {Loeb, Horst W. and Schartner, Karl-Heinz and Dachwald, Bernd and Ohndorf, Andreas and Seboldt, Wolfgang}, title = {An Interstellar - Heliopause mission using a combination of solar/radioisotope electric propulsion}, series = {Presented at the 32nd International Electric Propulsion Conference}, booktitle = {Presented at the 32nd International Electric Propulsion Conference}, pages = {1 -- 7}, year = {2011}, abstract = {There is common agreement within the scientific community that in order to understand our local galactic environment it will be necessary to send a spacecraft into the region beyond the solar wind termination shock. Considering distances of 200 AU for a new mission, one needs a spacecraft travelling at a speed of close to 10 AU/yr in order to keep the mission duration in the range of less than 25 yrs, a transfer time postulated by ESA.Two propulsion options for the mission have been proposed and discussed so far: the solar sail propulsion and the ballistic/radioisotope electric propulsion. As a further alternative, we here investigate a combination of solar-electric propulsion and radioisotope-electric propulsion. The solar-electric propulsion stage consists of six 22 cm diameter "RIT-22"ion thrusters working with a high specific impulse of 7377 s corresponding to a positive grid voltage of 5 kV. Solar power of 53 kW BOM is provided by a light-weight solar array. The REP-stage consists of four space-proven 10 cm diameter "RIT-10" ion thrusters that will be operating one after the other for 9 yrs in total. Four advanced radioisotope generators provide 648 W at BOM. The scientific instrument package is oriented at earlier studies. For its mass and electric power requirement 35 kg and 35 W are assessed, respectively. Optimized trajectory calculations, treated in a separate contribution, are based on our "InTrance" method.The program yields a burn out of the REP stage in a distance of 79.6 AU for a usage of 154 kg of Xe propellant. With a C3 = 45,1 (km/s)2 a heliocentric probe velocity of 10 AU/yr is reached at this distance, provided a close Jupiter gravity assist adds a velocity increment of 2.7 AU/yr. A transfer time of 23.8 yrs results for this scenario requiring about 450 kg Xe for the SEP stage, jettisoned at 3 AU. We interpret the SEP/REP propulsion as a competing alternative to solar sail and ballistic/REP propulsion. Omiting a Jupiter fly-by even allows more launch flexibility, leaving the mission duration in the range of the ESA specification.}, language = {en} } @inproceedings{KurulganDemirciLinderDemircietal.2010, author = {Kurulgan Demirci, Eylem and Linder, Peter and Demirci, Taylan and Gierkowski, Jessica R. and Digel, Ilya and Gossmann, Matthias and Temiz Artmann, Ayseg{\"u}l}, title = {rhAPC reduces the endothelial cell permeability via a decrease of cellular mechanical contractile tensions : [abstract]}, year = {2010}, abstract = {In this study, the CellDrum technology quanitfying cellular mechanical tension on a pico-scale was used to investigate the effect of LPS (lipopolysaccharide) on HAoEC (Human Aortic Endothelial Cell) tension.}, subject = {Endothelzelle}, language = {en} } @inproceedings{KuhlenDigel2017, author = {Kuhlen, Max and Digel, Ilya}, title = {Fluorescence signatures and detection limits of ubiquitous terrestrial bio-compounds}, series = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, booktitle = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, editor = {Erni, Daniel and Fischerauer, Alice and Himmel, J{\"o}rg and Seeger, Thomas and Thelen, Klaus}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-9814801-9-1}, doi = {10.17185/duepublico/43984}, pages = {102 -- 103}, year = {2017}, language = {en} } @inproceedings{KonstantinidisKowalskiMartinezetal.2015, author = {Konstantinidis, K. and Kowalski, Julia and Martinez, C. F. and Dachwald, Bernd and Ewerhart, D. and F{\"o}rstner, R.}, title = {Some necessary technologies for in-situ astrobiology on enceladus}, series = {Proceedings of the International Astronautical Congress}, booktitle = {Proceedings of the International Astronautical Congress}, isbn = {978-151081893-4}, pages = {1354 -- 1372}, year = {2015}, language = {en} } @inproceedings{KonstantinidisDachwaldOhndorfetal.2013, author = {Konstantinidis, K. and Dachwald, Bernd and Ohndorf, A. and Dykta, P. and Voigt, K. and F{\"o}rstner, R.}, title = {Enceladus explorer (ENEX): A lander mission to probe subglacial water pockets on Saturn's moon enceladus for life}, series = {64th International Astronautical Congress 2013 (IAC 2013) : Beijing, China, 23 - 27 September 2013. (Proceedings of the International Astronautical Congress, IAC ; 2)}, booktitle = {64th International Astronautical Congress 2013 (IAC 2013) : Beijing, China, 23 - 27 September 2013. (Proceedings of the International Astronautical Congress, IAC ; 2)}, publisher = {Curran}, address = {Red Hook, NY}, organization = {International Astronautical Congress <64, 2013, Beijing>}, isbn = {978-1-62993-909-4}, pages = {1340 -- 1350}, year = {2013}, language = {en} } @inproceedings{KolditzAlbrachtFasseetal.2015, author = {Kolditz, Melanie and Albracht, Kirsten and Fasse, Alessandro and Albin, Thivaharan and Br{\"u}ggemann, Gert-Peter and Abel, Dirk}, title = {Evaluation of an industrial robot as a leg press training device}, series = {XV International Symposium on Computer Simulation in Biomechanics July 9th - 11th 2015, Edinburgh, UK}, booktitle = {XV International Symposium on Computer Simulation in Biomechanics July 9th - 11th 2015, Edinburgh, UK}, pages = {41 -- 42}, year = {2015}, language = {en} } @inproceedings{KolditzAlbinFasseetal.2015, author = {Kolditz, Melanie and Albin, Thivaharan and Fasse, Alessandro and Br{\"u}ggemann, Gert-Peter and Abel, Dirk and Albracht, Kirsten}, title = {Simulative Analysis of Joint Loading During Leg Press Exercise for Control Applications}, series = {IFAC-PapersOnLine}, volume = {48}, booktitle = {IFAC-PapersOnLine}, number = {20}, doi = {10.1016/j.ifacol.2015.10.179}, pages = {435 -- 440}, year = {2015}, language = {en} } @inproceedings{KetelhutGoellBraunsteinetal.2019, author = {Ketelhut, Maike and G{\"o}ll, Fabian and Braunstein, Bjoern and Albracht, Kirsten and Abel, Dirk}, title = {Iterative learning control of an industrial robot for neuromuscular training}, series = {2019 IEEE Conference on Control Technology and Applications}, booktitle = {2019 IEEE Conference on Control Technology and Applications}, publisher = {IEEE}, address = {New York}, isbn = {978-1-7281-2767-5 (ePub)}, doi = {10.1109/CCTA.2019.8920659}, pages = {7 Seiten}, year = {2019}, abstract = {Effective training requires high muscle forces potentially leading to training-induced injuries. Thus, continuous monitoring and controlling of the loadings applied to the musculoskeletal system along the motion trajectory is required. In this paper, a norm-optimal iterative learning control algorithm for the robot-assisted training is developed. The algorithm aims at minimizing the external knee joint moment, which is commonly used to quantify the loading of the medial compartment. To estimate the external knee joint moment, a musculoskeletal lower extremity model is implemented in OpenSim and coupled with a model of an industrial robot and a force plate mounted at its end-effector. The algorithm is tested in simulation for patients with varus, normal and valgus alignment of the knee. The results show that the algorithm is able to minimize the external knee joint moment in all three cases and converges after less than seven iterations.}, language = {en} } @inproceedings{KahmannUschokWegmannetal.2018, author = {Kahmann, Stephanie Lucina and Uschok, Stephan and Wegmann, Kilian and M{\"u}ller, Lars-P. and Staat, Manfred}, title = {Biomechanical multibody model with refined kinematics of the elbow}, series = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, booktitle = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, pages = {11 Seiten}, year = {2018}, abstract = {The overall objective of this study is to develop a new external fixator, which closely maps the native kinematics of the elbow to decrease the joint force resulting in reduced rehabilitation time and pain. An experimental setup was designed to determine the native kinematics of the elbow during flexion of cadaveric arms. As a preliminary study, data from literature was used to modify a published biomechanical model for the calculation of the joint and muscle forces. They were compared to the original model and the effect of the kinematic refinement was evaluated. Furthermore, the obtained muscle forces were determined in order to apply them in the experimental setup. The joint forces in the modified model differed slightly from the forces in the original model. The muscle force curves changed particularly for small flexion angles but their magnitude for larger angles was consistent.}, language = {en} } @inproceedings{KahmannHacklWegmannetal.2016, author = {Kahmann, Stephanie and Hackl, Michael and Wegmann, Kilian and M{\"u}ller, Lars-Peter and Staat, Manfred}, title = {Impact of a proximal radial shortening osteotomy on the distribution of forces and the stability of the elbow}, series = {1st YRA MedTech Symposium 2016 : April 8th / 2016 / University of Duisburg-Essen}, booktitle = {1st YRA MedTech Symposium 2016 : April 8th / 2016 / University of Duisburg-Essen}, editor = {Erni, Daniel}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, doi = {10.17185/duepublico/40821}, pages = {7 -- 8}, year = {2016}, abstract = {The human arm consists of the humerus (upper arm), the medial ulna and the lateral radius (forearm). The joint between the humerus and the ulna is called humeroulnar joint and the joint between the humerus and the radius is called humeroradial joint. Lateral and medial collateral ligaments stabilize the elbow. Statistically, 2.5 out of 10,000 people suffer from radial head fractures [1]. In these fractures the cartilage is often affected. Caused by the injured cartilage, degenerative diseases like posttraumatic arthrosis may occur. The resulting pain and reduced range of motion have an impact on the patient's quality of life. Until now, there has not been a treatment which allows typical loads in daily life activities and offers good long-term results. A new surgical approach was developed with the motivation to reduce the progress of the posttraumatic arthrosis. Here, the radius is shortened by 3 mm in the proximal part [2]. By this means, the load of the radius is intended to be reduced due to a load shift to the ulna. Since the radius is the most important stabilizer of the elbow it has to be confirmed that the stability is not affected. In the first test (Fig. 1 left), pressure distributions within the humeroulnar and humeroradial joints a native and a shortened radius were measured using resistive pressure sensors (I5076 and I5027, Tekscan, USA). The humerus was loaded axially in a tension testing machine (Z010, Zwick Roell, Germany) in 50 N steps up to 400 N. From the humerus the load is transmitted through both the radius and the ulna into the hand which is fixed on the ground. In the second test (Fig. 1 right), the joint stability was investigated using a digital image correlation system to measure the displacement of the ulna. Here, the humerus is fixed with a desired flexion angle and the unconstrained forearm lies on the ground. A rope connects the load actuator with a hook fixed in the ulna. A guide roller is used so that the rope pulls the ulna horizontally when a tensile load is applied. This creates a moment about the elbow joint with a maximum value of 7.5 Nm. Measurements were performed with varying flexion angles (0°, 30°, 60°, 90°, 120°). For both tests and each measurement, seven specimens were used. Student's t-test was employed to determine whether the mean values of the measurements in native specimen and operated specimens differ significantly.}, language = {en} } @inproceedings{JungStaatMueller2014, author = {Jung, Alexander and Staat, Manfred and M{\"u}ller, Wolfram}, title = {Optimization of the flight style in ski jumping}, series = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20 - 25, 2014, Barcelona}, booktitle = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20 - 25, 2014, Barcelona}, editor = {Onate, E.}, organization = {World Congress on Computational Mechanics <11, 2014, Barcelona>}, pages = {799 -- 810}, year = {2014}, language = {en} } @inproceedings{JungStaatMueller2016, author = {Jung, Alexander and Staat, Manfred and M{\"u}ller, Wolfram}, title = {Effect of wind on flight style optimisation in ski jumping}, series = {15th International Symposium on Computer Simulation in Biomechanics ; July 9th-11th 2015, Edinburgh, UK}, booktitle = {15th International Symposium on Computer Simulation in Biomechanics ; July 9th-11th 2015, Edinburgh, UK}, publisher = {The University of Edinburgh ; Loughborough University}, address = {Edinburgh}, pages = {53 -- 54}, year = {2016}, language = {en} } @inproceedings{JungStaat2016, author = {Jung, Alexander and Staat, Manfred}, title = {Computing olympic gold: Ski jumping as an example}, series = {1st YRA MedTech Symposium 2016 : April 8th / 2016 / University of Duisburg-Essen}, booktitle = {1st YRA MedTech Symposium 2016 : April 8th / 2016 / University of Duisburg-Essen}, editor = {Erni, Daniel}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-06-6}, doi = {10.17185/duepublico/40821}, pages = {54 -- 55}, year = {2016}, language = {en} } @inproceedings{JungFrotscherStaat2018, author = {Jung, Alexander and Frotscher, Ralf and Staat, Manfred}, title = {Electromechanical model of hiPSC-derived ventricular cardiomyocytes cocultured with fibroblasts}, series = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, booktitle = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, pages = {11 Seiten}, year = {2018}, abstract = {The CellDrum provides an experimental setup to study the mechanical effects of fibroblasts co-cultured with hiPSC-derived ventricular cardiomyocytes. Multi-scale computational models based on the Finite Element Method are developed. Coupled electrical cardiomyocyte-fibroblast models (cell level) are embedded into reaction-diffusion equations (tissue level) which compute the propagation of the action potential in the cardiac tissue. Electromechanical coupling is realised by an excitation-contraction model (cell level) and the active stress arising during contraction is added to the passive stress in the force balance, which determines the tissue displacement (tissue level). Tissue parameters in the model can be identified experimentally to the specific sample.}, language = {en} } @inproceedings{JeanPierrePBaqueBillietal.2018, author = {Jean-Pierre P., de Vera and Baque, Mickael and Billi, Daniela and B{\"o}ttger, Ute and Bulat, Sergey and Czupalla, Markus and Dachwald, Bernd and de la Torre, Rosa and Elsaesser, Andreas and Foucher, Fr{\´e}d{\´e}ric and Korsitzky, Hartmut and Kozyrovska, Natalia and L{\"a}ufer, Andreas and Moeller, Ralf and Olsson-Francis, Karen and Onofri, Silvano and Sommer, Stefan and Wagner, Dirk and Westall, Frances}, title = {The search for life on Mars and in the Solar System - strategies, logistics and infrastructures}, series = {69th International Astronautical Congress (IAC)}, booktitle = {69th International Astronautical Congress (IAC)}, pages = {1 -- 8}, year = {2018}, abstract = {The question "Are we alone in the Universe?" is perhaps the most fundamental one that affects mankind. How can we address the search for life in our Solar System? Mars, Enceladus and Europa are the focus of the search for life outside the terrestrial biosphere. While it is more likely to find remnants of life (fossils of extinct life) on Mars because of its past short time window of the surface habitability, it is probably more likely to find traces of extant life on the icy moons and ocean worlds of Jupiter and Saturn. Nevertheless, even on Mars there could still be a chance to find extant life in niches near to the surface or in just discovered subglacial lakes beneath the South Pole ice cap. Here, the different approaches for the detection of traces of life in the form of biosignatures including pre-biotic molecules will be presented. We will outline the required infrastructure for this enterprise and give examples of future mission concepts to investigate the presence of life on other planets and moons. Finally, we will provide suggestions on methods, techniques, operations and strategies for preparation and realization of future life detection missions.}, language = {en} } @inproceedings{JabbariBhattaraiAndingetal.2017, author = {Jabbari, Medisa and Bhattarai, Aroj and Anding, Ralf and Staat, Manfred}, title = {Biomechanical simulation of different prosthetic meshes for repairing uterine/vaginal vault prolapse}, series = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, booktitle = {2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West}, editor = {Erni, Daniel and Fischerauer, Alice and Himmel, J{\"o}rg and Seeger, Thomas and Thelen, Klaus}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-9814801-9-1}, doi = {10.17185/duepublico/43984}, pages = {118 -- 119}, year = {2017}, language = {en} } @inproceedings{IomdinaKiselevaKotliaretal.2020, author = {Iomdina, Elena N. and Kiseleva, Anna A. and Kotliar, Konstantin and Luzhnov, Petr V.}, title = {Quantification of Choroidal Blood Flow Using the OCT-A System Based on Voxel Scan Processing}, series = {2020 International Conference on Biomedical Innovations and Applications (BIA)}, booktitle = {2020 International Conference on Biomedical Innovations and Applications (BIA)}, isbn = {978-1-7281-7073-2}, doi = {10.1109/BIA50171.2020.9244511}, pages = {41 -- 44}, year = {2020}, language = {en} } @inproceedings{HunkerJungGossmannetal.2019, author = {Hunker, Jan and Jung, Alexander and Goßmann, Matthias and Linder, Peter and Staat, Manfred}, title = {Development of a tool to analyze the conduction speed in microelectrode array measurements of cardiac tissue}, series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen}, booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen}, editor = {Staat, Manfred and Erni, Daniel}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-22-6}, doi = {10.17185/duepublico/48750}, pages = {7 -- 8}, year = {2019}, abstract = {The discovery of human induced pluripotent stem cells reprogrammed from somatic cells [1] and their ability to differentiate into cardiomyocytes (hiPSC-CMs) has provided a robust platform for drug screening [2]. Drug screenings are essential in the development of new components, particularly for evaluating the potential of drugs to induce life-threatening pro-arrhythmias. Between 1988 and 2009, 14 drugs have been removed from the market for this reason [3]. The microelectrode array (MEA) technique is a robust tool for drug screening as it detects the field potentials (FPs) for the entire cell culture. Furthermore, the propagation of the field potential can be examined on an electrode basis. To analyze MEA measurements in detail, we have developed an open-source tool.}, language = {en} } @inproceedings{HallmannHeideckerSchlottereretal.2016, author = {Hallmann, Marcus and Heidecker, Ansgar and Schlotterer, Markus and Dachwald, Bernd}, title = {GTOC8: results and methods of team 15 DLR}, series = {26th AAS/AIAA Space Flight Mechanics Meeting, Napa, CA}, booktitle = {26th AAS/AIAA Space Flight Mechanics Meeting, Napa, CA}, year = {2016}, abstract = {This paper describes the results and methods used during the 8th Global Trajectory Optimization Competition (GTOC) of the DLR team. Trajectory optimization is crucial for most of the space missions and usually can be formulated as a global optimization problem. A lot of research has been done to different type of mission problems. The most demanding ones are low thrust transfers with e.g. gravity assist sequences. In that case the optimal control problem is combined with an integer problem. In most of the GTOCs we apply a filtering of the problem based on domain knowledge.}, language = {en} } @inproceedings{GrundmannMessBieleetal.2017, author = {Grundmann, Jan Thimo and Meß, Jan-Gerd and Biele, Jens and Seefeldt, Patric and Dachwald, Bernd and Spietz, Peter and Grimm, Christian D. and Spr{\"o}witz, Tom and Lange, Caroline and Ulamec, Stephan}, title = {Small spacecraft in small solar system body applications}, series = {IEEE Aerospace Conference 2017, Big Sky, Montana, USA}, booktitle = {IEEE Aerospace Conference 2017, Big Sky, Montana, USA}, organization = {IEEE Aerospace Conference}, isbn = {978-1-5090-1613-6}, doi = {10.1109/AERO.2017.7943626}, pages = {1 -- 20}, year = {2017}, language = {en} } @inproceedings{GrundmannLangeDachwaldetal.2015, author = {Grundmann, Jan Thimo and Lange, Caroline and Dachwald, Bernd and Grimm, Christian and Koch, Aaron and Ulamec, Stephan}, title = {Small Spacecraft in Planetary Defence Related Applications-Capabilities, Constraints, Challenges}, series = {IEEE Aerospace Conference}, booktitle = {IEEE Aerospace Conference}, pages = {1 -- 18}, year = {2015}, abstract = {In this paper we present an overview of the characteristics and peculiarities of small spacecraft missions related to planetary defence applications. We provide a brief overview of small spacecraft missions to small solar system bodies. On this background we present recent missions and selected projects and related studies at the German Aerospace Center, DLR, that contribute to planetary defence related activities. These range from Earth orbit technology demonstrators to active science missions in interplanetary space. We provide a summary of experience from recently flown missions with DLR participation as well as a number of studies. These include PHILAE, the lander recently arrived on comet 67P/Churyumov-Gerasimenko aboard ESA's ROSETTA comet rendezvous mission, and the Mobile Asteroid Surface Scout, MASCOT, now underway to near-Earth asteroid (162173) 1999 JU3 aboard the Japanese sample-return probe HAYABUSA-2. We introduce the differences between the conventional methods employed in the design, integration and testing of large spacecraft and the new approaches developed by small spacecraft projects. We expect that the practical experience that can be gained from projects on extremely compressed timelines or with high-intensity operation phases on a newly explored small solar system body can contribute significantly to the study, preparation and realization of future planetary defence related missions. One is AIDA (Asteroid Impact \& Deflection Assessment), a joint effort of ESA,JHU/APL, NASA, OCA and DLR, combining JHU/APL's DART (Double Asteroid Redirection Test) and ESA's AIM (Asteroid Impact Monitor) spacecraft in a mission towards near-Eath binary asteroid (65803) Didymos.}, language = {en} } @inproceedings{GrundmannBorellaCeriottietal.2021, author = {Grundmann, Jan Thimo and Borella, Laura and Ceriotti, Matteo and Chand, Suditi and Cordero, Federico and Dachwald, Bernd and Fexer, Sebastian and Grimm, Christian D. and Hendrikse, Jeffrey and Herč{\´i}k, David and Herique, Alain and Hillebrandt, Martin and Ho, Tra-Mi and Kesseler, Lars and Laabs, Martin and Lange, Caroline and Lange, Michael and Lichtenheldt, Roy and McInnes, Colin R. and Moore, Iain and Peloni, Alessandro and Plettenmeier, Dirk and Quantius, Dominik and Seefeldt, Patric and Venditti, Flaviane c. F. and Vergaaij, Merel and Viavattene, Giulia and Virkki, Anne K. and Zander, Martin}, title = {More bucks for the bang: new space solutions, impact tourism and one unique science \& engineering opportunity at T-6 months and counting}, series = {7th IAA Planetary Defense Conference}, booktitle = {7th IAA Planetary Defense Conference}, year = {2021}, abstract = {For now, the Planetary Defense Conference Exercise 2021's incoming fictitious(!), asteroid, 2021 PDC, seems headed for impact on October 20th, 2021, exactly 6 months after its discovery. Today (April 26th, 2021), the impact probability is 5\%, in a steep rise from 1 in 2500 upon discovery six days ago. We all know how these things end. Or do we? Unless somebody kicked off another headline-grabbing media scare or wants to keep civil defense very idle very soon, chances are that it will hit (note: this is an exercise!). Taking stock, it is barely 6 months to impact, a steadily rising likelihood that it will actually happen, and a huge uncertainty of possible impact energies: First estimates range from 1.2 MtTNT to 13 GtTNT, and this is not even the worst-worst case: a 700 m diameter massive NiFe asteroid (covered by a thin veneer of Ryugu-black rubble to match size and brightness), would come in at 70 GtTNT. In down to Earth terms, this could be all between smashing fireworks over some remote area of the globe and a 7.5 km crater downtown somewhere. Considering the deliberate and sedate ways of development of interplanetary missions it seems we can only stand and stare until we know well enough where to tell people to pack up all that can be moved at all and save themselves. But then, it could just as well be a smaller bright rock. The best estimate is 120 m diameter from optical observation alone, by 13\% standard albedo. NASA's upcoming DART mission to binary asteroid (65803) Didymos is designed to hit such a small target, its moonlet Dimorphos. The Deep Impact mission's impactor in 2005 successfully guided itself to the brightest spot on comet 9P/Tempel 1, a relatively small feature on the 6 km nucleus. And 'space' has changed: By the end of this decade, one satellite communication network plans to have launched over 11000 satellites at a pace of 60 per launch every other week. This level of series production is comparable in numbers to the most prolific commercial airliners. Launch vehicle production has not simply increased correspondingly - they can be reused, although in a trade for performance. Optical and radio astronomy as well as planetary radar have made great strides in the past decade, and so has the design and production capability for everyday 'high-tech' products. 60 years ago, spaceflight was invented from scratch within two years, and there are recent examples of fast-paced space projects as well as a drive towards 'responsive space'. It seems it is not quite yet time to abandon all hope. We present what could be done and what is too close to call once thinking is shoved out of the box by a clear and present danger, to show where a little more preparedness or routine would come in handy - or become decisive. And if we fail, let's stand and stare safely and well instrumented anywhere on Earth together in the greatest adventure of science.}, language = {en} } @inproceedings{GrundmannBodenCeriottietal.2017, author = {Grundmann, Jan Thimo and Boden, Ralf and Ceriotti, Matteo and Dachwald, Bernd and Dumont, Etienne and Grimm, Christian D. and Lange, Caroline and Lichtenheldt, Roy and Pelivan, Ivanka and Peloni, Alessandro and Riemann, Johannes and Spr{\"o}witz, Tom and Tardivel, Simon}, title = {Soil to sail-asteroid landers on near-term sailcraft as an evolution of the GOSSAMER small spacecraft solar sail concept for in-situ characterization}, series = {5th IAA Planetary Defense Conference}, booktitle = {5th IAA Planetary Defense Conference}, pages = {30 Seiten}, year = {2017}, language = {en} } @inproceedings{GrundmannBieleDachwaldetal.2016, author = {Grundmann, Jan Thimo and Biele, Jens and Dachwald, Bernd and Grimm, Christian and Lange, Caroline and Ulamec, Stephan}, title = {Small spacecraft for small solar system body science, planetary defence and applications}, series = {IEEE Aerospace Conference 2016}, booktitle = {IEEE Aerospace Conference 2016}, pages = {1 -- 20}, year = {2016}, abstract = {Following the recent successful landings and occasional re-awakenings of PHILAE, the lander carried aboard ROSETTA to comet 67P/Churyumov-Gerasimenko, and the launch of the Mobile Asteroid Surface Scout, MASCOT, aboard the HAYABUSA2 space probe to asteroid (162173) Ryugu we present an overview of the characteristics and peculiarities of small spacecraft missions to small solar system bodies (SSSB). Their main purpose is planetary science which is transitioning from a 'pure' science of observation of the distant to one also supporting in-situ applications relevant for life on Earth. Here we focus on missions at the interface of SSSB science and planetary defence applications. We provide a brief overview of small spacecraft SSSB missions and on this background present recent missions, projects and related studies at the German Aerospace Center, DLR, that contribute to the worldwide planetary defence community. These range from Earth orbit technology demonstrators to active science missions in interplanetary space. We provide a summary of experience from recently flown missions with DLR participation as well as a number of studies. These include PHILAE, the lander of ESA's ROSETTA comet rendezvous mission now on the surface of comet 67P/Churyumov-Gerasimenko, and the Mobile Asteroid Surface Scout, MASCOT, now in cruise to the ~1 km diameter C-type near-Earth asteroid (162173) Ryugu aboard the Japanese sample-return probe HAYABUSA2. We introduce the differences between the conventional methods employed in the design, integration and testing of large spacecraft and the new approaches developed by small spacecraft projects. We expect that the practical experience that can be gained from projects on extremely compressed timelines or with high-intensity operation phases on a newly explored small solar system body can contribute significantly to the study, preparation and realization of future planetary defence related missions. One is AIDA (Asteroid Impact \& Deflection Assessment), a joint effort of ESA, JHU/APL, NASA, OCA and DLR, combining JHU/APL's DART (Double Asteroid Redirection Test) and ESA's AIM (Asteroid Impact Monitor) spacecraft in a mission towards near-Earth binary asteroid system (65803) Didymos. DLR is currently applying MASCOT heritage and lessons learned to the design of MASCOT2, a lander for the AIM mission to support a bistatic low frequency radar experiment with PHILAE/ROSETTA CONSERT heritage to explore the inner structure of Didymoon which is the designated impact target for DART.}, language = {en} } @inproceedings{GrundmannBieleDachwaldetal.2017, author = {Grundmann, Jan Thimo and Biele, Jens and Dachwald, Bernd and Grimm, Christian D. and Lange, Caroline and Ulamec, Stephan and Ziach, Christian and Spr{\"o}witz, Tom and Ruffer, Michael and Seefeldt, Patric and Spietz, Peter and Toth, Norbert and Mimasu, Yuya and Rittweger, Andreas and Bibring, Jean-Pierre and Braukhane, Andy and Boden, Ralf Christian and Dumont, Etienne and Jahnke, Stephan Siegfried and Jetzschmann, Michael and Kr{\"u}ger, Hans and Lange, Michael and Gomez, Antonio Martelo and Massonett, Didier and Okada, Tatsuaki and Sagliano, Marco and Sasaki, Kaname and Schr{\"o}der, Silvio and Sippel, Martin and Skoczylas, Thomas and Wejmo, Elisabet}, title = {Small landers and separable sub-spacecraft for near-term solar sails}, series = {The Fourth International Symposium on Solar Sailing 2017}, booktitle = {The Fourth International Symposium on Solar Sailing 2017}, pages = {1 -- 10}, year = {2017}, abstract = {Following the successful PHILAE landing with ESA's ROSETTA probe and the launch of the MINERVA rovers and the Mobile Asteroid Surface Scout, MASCOT, aboard the JAXA space probe, HAYABUSA2, to asteroid (162173) Ryugu, small landers have found increasing interest. Integrated at the instrument level in their mothership they support small solar system body studies. With efficient capabilities, resource-friendly design and inherent robustness they are an attractive exploration mission element. We discuss advantages and constraints of small sub-spacecraft, focusing on emerging areas of activity such as asteroid diversity studies, planetary defence, and asteroid mining, on the background of our projects PHILAE, MASCOT, MASCOT2, the JAXA-DLR Solar Power Sail Lander Design Study, and others. The GOSSAMER-1 solar sail deployment concept also involves independent separable sub-spacecraft operating synchronized to deploy the sail. Small spacecraft require big changes in the way we do things and occasionally a little more effort than would be anticipated based on a traditional large spacecraft approach. In a Constraints-Driven Engineering environment we apply Concurrent Design and Engineering (CD/CE), Concurrent Assembly, Integration and Verification (CAIV) and Model-Based Systems Engineering (MBSE). Near-term solar sails will likely be small spacecraft which we expect to harmonize well with nano-scale separable instrument payload packages.}, language = {en} } @inproceedings{GrundmannBauerBorchersetal.2019, author = {Grundmann, Jan Thimo and Bauer, Wlademar and Borchers, Kai and Dumont, Etienne and Grimm, Christian D. and Ho, Tra-Mi and Jahnke, Rico and Koch, Aaron D. and Lange, Caroline and Maiwald, Volker and Meß, Jan-Gerd and Mikulz, Eugen and Quantius, Dominik and Reershemius, Siebo and Renger, Thomas and Sasaki, Kaname and Seefeldt, Patric and Spietz, Peter and Spr{\"o}witz, Tom and Sznajder, Maciej and Toth, Norbert and Ceriotti, Matteo and McInnes, Colin and Peloni, Alessandro and Biele, Jens and Krause, Christian and Dachwald, Bernd and Hercik, David and Lichtenheldt, Roy and Wolff, Friederike and Koncz, Alexander and Pelivan, Ivanka and Schmitz, Nicole and Boden, Ralf and Riemann, Johannes and Seboldt, Wolfgang and Wejmo, Elisabet and Ziach, Christian and Mikschl, Tobias and Montenegro, Sergio and Ruffer, Michael and Cordero, Federico and Tardivel, Simon}, title = {Solar sails for planetary defense \& high-energy missions}, series = {IEEE Aerospace Conference Proceedings}, booktitle = {IEEE Aerospace Conference Proceedings}, doi = {10.1109/AERO.2019.8741900}, pages = {1 -- 21}, year = {2019}, abstract = {20 years after the successful ground deployment test of a (20 m) 2 solar sail at DLR Cologne, and in the light of the upcoming U.S. NEAscout mission, we provide an overview of the progress made since in our mission and hardware design studies as well as the hardware built in the course of our solar sail technology development. We outline the most likely and most efficient routes to develop solar sails for useful missions in science and applications, based on our developed `now-term' and near-term hardware as well as the many practical and managerial lessons learned from the DLR-ESTEC Gossamer Roadmap. Mission types directly applicable to planetary defense include single and Multiple NEA Rendezvous ((M)NR) for precursor, monitoring and follow-up scenarios as well as sail-propelled head-on retrograde kinetic impactors (RKI) for mitigation. Other mission types such as the Displaced L1 (DL1) space weather advance warning and monitoring or Solar Polar Orbiter (SPO) types demonstrate the capability of near-term solar sails to achieve asteroid rendezvous in any kind of orbit, from Earth-coorbital to extremely inclined and even retrograde orbits. Some of these mission types such as SPO, (M)NR and RKI include separable payloads. For one-way access to the asteroid surface, nanolanders like MASCOT are an ideal match for solar sails in micro-spacecraft format, i.e. in launch configurations compatible with ESPA and ASAP secondary payload platforms. Larger landers similar to the JAXA-DLR study of a Jupiter Trojan asteroid lander for the OKEANOS mission can shuttle from the sail to the asteroids visited and enable multiple NEA sample-return missions. The high impact velocities and re-try capability achieved by the RKI mission type on a final orbit identical to the target asteroid's but retrograde to its motion enables small spacecraft size impactors to carry sufficient kinetic energy for deflection.}, language = {en} } @inproceedings{GrundmannBauerBorchersetal.2018, author = {Grundmann, Jan Thimo and Bauer, Waldemar and Borchers, Kai and Dumont, Etienne and Grimm, Christian D. and Ho, Tra-Mi and Jahnke, Rico and Lange, Caroline and Maiwald, Volker and Mikulz, Eugen and Quantius, Dominik and Reershemius, Siebo and Renger, Thomas and Riemann, Johannes and Sasaki, Kaname and Seefeldt, Patric and Spietz, Peter and Spr{\"o}witz, Tom and Toth, Norbert and Wejmo, Elisabet and Biele, Jens and Krause, Christian and Cerotti, Matteo and Peloni, Alessandro and Dachwald, Bernd}, title = {Small Spacecraft Solar Sailing for Small Solar System Body Multiple Rendezvous and Landing}, series = {2018 IEEE Aerospace Conference : 3-10 March 2018}, booktitle = {2018 IEEE Aerospace Conference : 3-10 March 2018}, isbn = {978-1-5386-2014-4}, pages = {20 Seiten}, year = {2018}, language = {en} } @inproceedings{GrundmannBauerBodenetal.2019, author = {Grundmann, Jan Thimo and Bauer, Waldemar and Boden, Ralf Christian and Ceriotti, Matteo and Cordero, Federico and Dachwald, Bernd and Dumont, Etienne and Grimm, Christian D. and Hercik, D. and Herique, A. and Ho, Tra-Mi and Jahnke, Rico and Kofman, Wlodek and Lange, Caroline and Lichtenheldt, Roy and McInnes, Colin R. and Mikschl, Tobias and Montenegro, Sergio and Moore, Iain and Pelivan, Ivanka and Peloni, Alessandro and Plettenmeier, Dirk and Quantius, Dominik and Reershemius, Siebo and Renger, Thomas and Riemann, Johannes and Rogez, Yves and Ruffer, Michael and Sasaki, Kaname and Schmitz, Nicole and Seboldt, Wolfgang and Seefeldt, Patric and Spietz, Peter and Spr{\"o}witz, Tom and Sznajder, Maciej and Toth, Norbert and Viavattene, Giulia and Wejmo, Elisabet and Wolff, Friederike and Ziach, Christian}, title = {Responsive exploration and asteroid characterization through integrated solar sail and lander development using small spacecraft technologies}, series = {IAA Planetary Defense Conference}, booktitle = {IAA Planetary Defense Conference}, year = {2019}, abstract = {In parallel to the evolution of the Planetary Defense Conference, the exploration of small solar system bodies has advanced from fast fly-bys on the sidelines of missions to the planets to the implementation of dedicated sample-return and in-situ analysis missions. Spacecraft of all sizes have landed, touch-and-go sampled, been gently beached, or impacted at hypervelocity on asteroid and comet surfaces. More have flown by close enough to image their surfaces in detail or sample their immediate environment, often as part of an extended or re-purposed mission. And finally, full-scale planetary defense experiment missions are in the making. Highly efficient low-thrust propulsion is increasingly applied beyond commercial use also in mainstream and flagship science missions, in combination with gravity assist propulsion. Another development in the same years is the growth of small spacecraft solutions, not in size but in numbers and individual capabilities. The on-going NASA OSIRIS-REx and JAXA HAYABUSA2 missions exemplify the trend as well as the upcoming NEA SCOUT mission or the landers MINERVA-II and MASCOT recently deployed on Ryugu. We outline likely as well as possible and efficient routes of continuation of all these developments towards a propellant-less and highly efficient class of spacecraft for small solar system body exploration: small spacecraft solar sails designed for carefree handling and equipped with carried landers and application modules, for all asteroid user communities -planetary science, planetary defence, and in-situ resource utilization. This projection builds on the experience gained in the development of deployable membrane structures leading up to the successful ground deployment test of a (20 m)² solar sail at DLR Cologne and in the 20 years since. It draws on the background of extensive trajectory optimization studies, the qualified technology of the DLR GOSSAMER-1 deployment demonstrator, and the MASCOT asteroid lander. These enable 'now-term' as well as near-term hardware solutions, and thus responsive fast-paced development. Mission types directly applicable to planetary defense include: single and Multiple NEA Rendezvous ((M)NR) for mitigation precursor, target monitoring and deflection follow-up tasks; sail-propelled head-on retrograde kinetic impactors (RKI) for mitigation; and deployable membrane based methods to modify the asteroid's properties or interact with it. The DLR-ESTEC GOSSAMER Roadmap initiated studies of missions uniquely feasible with solar sails such as Displaced L1 (DL1) space weather advance warning and monitoring and Solar Polar Orbiter (SPO) delivery which demonstrate the capability of near-term solar sails to achieve NEA rendezvous in any kind of orbit, from Earth-coorbital to extremely inclined and even retrograde orbits. For those mission types using separable payloads, such as SPO, (M)NR and RKI, design concepts can be derived from the separable Boom Sail Deployment Units characteristic of DLR GOSSAMER solar sail technology, nanolanders like MASCOT, or microlanders like the JAXA-DLR Jupiter Trojan Asteroid Lander for the OKEANOS mission which can shuttle from the sail to the asteroids visited and enable multiple NEA sample-return missions. These are an ideal match for solar sails in micro-spacecraft format whose launch configurations are compatible with ESPA and ASAP secondary payload platforms.}, language = {en} } @inproceedings{GrundmannBauerBodenetal.2019, author = {Grundmann, Jan Thimo and Bauer, Waldemar and Boden, Ralf Christian and Ceriotti, Matteo and Cordero, Federico and Dachwald, Bernd and Dumont, Etienne and Grimm, Christian D. and Hercik, D. and Herique, A. and Ho, Tra-Mi and Jahnke, Rico and Kofman, Wlodek and Lange, Caroline and Lichtenheldt, Roy and McInnes, Colin R. and Mikschl, Tobias and Mikulz, Eugen and Montenegro, Sergio and Moore, Iain and Pelivan, Ivanka and Peloni, Alessandro and Plettemeier, Dirk and Quantius, Dominik and Reershemius, Siebo and Renger, Thomas and Riemann, Johannes and Rogez, Yves and Ruffer, Michael and Sasaki, Kaname and Schmitz, Nicole and Seboldt, Wolfgang and Seefeldt, Patric and Spietz, Peter and Spr{\"o}witz, Tom and Sznajder, Maciej and Toth, Norbert and Viavattene, Giulia and Wejmo, Elisabet and Wolff, Friederike and Ziach, Christian}, title = {Responsive integrated small spacecraft solar sail and payload design concepts and missions}, series = {Conference: 5th International Symposium on Solar Sailing (ISSS 2019)}, booktitle = {Conference: 5th International Symposium on Solar Sailing (ISSS 2019)}, year = {2019}, abstract = {Asteroid mining has the potential to greatly reduce the cost of in-space manufacturing, production of propellant for space transportation and consumables for crewed spacecraft, compared to launching the required resources from Earth's deep gravity well. This paper discusses the top-level mission architecture and trajectory design for these resource-return missions, comparing high-thrust trajectories with continuous low-thrust solar-sail trajectories. This work focuses on maximizing the economic Net Present Value, which takes the time-cost of finance into account and therefore balances the returned resource mass and mission duration. The different propulsion methods will then be compared in terms of maximum economic return, sets of attainable target asteroids, and mission flexibility. This paper provides one more step towards making commercial asteroid mining an economically viable reality by integrating trajectory design, propulsion technology and economic modelling.}, language = {en} } @inproceedings{GrundmannBauerBodenetal.2019, author = {Grundmann, Jan Thimo and Bauer, Waldemar and Boden, Ralf and Ceriotti, Matteo and Chand, Suditi and Cordero, Federico and Dachwald, Bernd and Dumont, Etienne and Grimm, Christian D. and Heiligers, Jeannette and Herč{\´i}k, David and H{\´e}rique, Alain and Ho, Tra-Mi and Jahnke, Rico and Kofman, Wlodek and Lange, Caroline and Lichtenheldt, Roy and McInnes, Colin and Meß, Jan-Gerd and Mikschl, Tobias and Mikulz, Eugen and Montenegro, Sergio and Moore, Iain and Pelivan, Ivanka and Peloni, Alessandro and Plettemeier, Dirk and Quantius, Dominik and Reershemius, Siebo and Renger, Thomas and Riemann, Johannes and Rogez, Yves and Ruffer, Michael and Sasaki, Kaname and Schmitz, Nicole and Seboldt, Wolfgang and Seefeldt, Patric and Spietz, Peter and Spr{\"o}witz, Tom and Sznajder, Maciej and T{\´o}th, Norbert and Vergaaij, Merel and Viavattene, Giulia and Wejmo, Elisabet and Wiedemann, Carsten and Wolff, Friederike and Ziach, Christian}, title = {Flights are ten a sail - Re-use and commonality in the design and system engineering of small spacecraft solar sail missions with modular hardware for responsive and adaptive exploration}, series = {70th International Astronautical Congress (IAC)}, booktitle = {70th International Astronautical Congress (IAC)}, isbn = {9781713814856}, pages = {1 -- 7}, year = {2019}, language = {en} } @inproceedings{GrundmannBauerBieleetal.2015, author = {Grundmann, Jan Thimo and Bauer, Waldemar and Biele, Jens and Cordero, Frederico and Dachwald, Bernd and Koncz, Alexander and Krause, Christian and Mikschl, Tobias and Montenegro, Sergio and Quantius, Dominik and Ruffer, Michael and Sasaki, Kaname and Schmitz, Nicole and Seefeldt, Patric and T{\´o}th, Norbert and Wejmo, Elisabet}, title = {From Sail to Soil - Getting Sailcraft Out of the Harbour on a Visit to One of Earth's Nearest Neighbours}, series = {4th IAA Planetary Denfense Conference - PDC 2015, 13-17 April 2015, Frascati, Roma, Italy}, booktitle = {4th IAA Planetary Denfense Conference - PDC 2015, 13-17 April 2015, Frascati, Roma, Italy}, pages = {20 S.}, year = {2015}, language = {en} } @inproceedings{GrundmannBauerBieleetal.2018, author = {Grundmann, Jan Thimo and Bauer, Waldemar and Biele, Jens and Boden, Ralf and Ceriotti, Matteo and Cordero, Federico and Dachwald, Bernd and Dumont, Etienne and Grimm, Christian and Herč{\´i}k, David and Herique, Alain and Ho, Tra-Mi and Jahnke, Rico and Koch, Aaron and Kofman, Wlodek and Koncz, Alexander and Krause, Christian and Lange, Caroline and Lichtenheldt, Roy and Maiwald, Volker and Mikschl, Tobias and Mikulz, Eugen and Montenegro, Sergio and Pelivan, Ivanka and Peloni, Alessandro and Plettemeier, Dirk and Quantius, Dominik and Reershemius, Siebo and Renger, Thomas and Riemann, Johannes and Ruffer, Michael and Sasaki, Kaname and Schmitz, Nicole and Seboldt, Wolfgang and Seefeldt, Patric and Spietz, Peter and Spr{\"o}witz, Tom and Sznajder, Maciej and Tardivel, Simon and Toth, Norbert and Wejmo, Elisabet and Wolff, Friederike and Ziach, Christian}, title = {Efficient massively parallel prospection for ISRU by multiple near-earth asteroid rendezvous using near-term solar sails and'now-term'small spacecraft solutions}, series = {2nd Asteroid Science Intersections with In-Space Mine Engineering - ASIME 2018}, booktitle = {2nd Asteroid Science Intersections with In-Space Mine Engineering - ASIME 2018}, pages = {1 -- 33}, year = {2018}, abstract = {Physical interaction with small solar system bodies (SSSB) is key for in-situ resource utilization (ISRU). The design of mining missions requires good understanding of SSSB properties, including composition, surface and interior structure, and thermal environment. But as the saying goes "If you've seen one asteroid, you've seen one Asteroid": Although some patterns may begin to appear, a stable and reliable scheme of SSSB classification still has to be evolved. Identified commonalities would enable generic ISRU technology and spacecraft design approaches with a high degree of re-use. Strategic approaches require much broader in-depth characterization of the SSSB populations of interest to the ISRU community. The DLR-ESTEC GOSSAMER Roadmap Science Working Groups identified target-flexible Multiple Near-Earth asteroid (NEA) Rendezvous (MNR) as one of the missions only feasible with solar sail propulsion, showed the ability to access any inclination and a wide range of heliocentric distances as well as continuous operation close to Earth's orbit where low delta-v objects reside.}, language = {en} } @inproceedings{GrundmannBauerBieleetal.2018, author = {Grundmann, Jan Thimo and Bauer, Waldemar and Biele, Jens and Boden, Ralf and Ceriotti, Matteo and Cordero, Federico and Dachwald, Bernd and Dumont, Etienne and Grimm, Christian D. and Herč{\´i}k, David and Ho, Tra-Mi and Jahnke, Rico and Koch, Aaron D and Koncz, Alexander and Krause, Christian and Lange, Caroline and Lichtenheldt, Roy and Maiwald, Volker and Mikschl, Tobias and Mikulz, Eugen and Montenegro, Sergio and Pelivan, Ivanka and Peloni, Alessandro and Quantius, Dominik and Reershemius, Siebo and Renger, Thomas and Riemann, Johannes and Ruffer, Michael and Sasaki, Kaname and Schmitz, Nicole and Seboldt, Wolfgang and Seefeldt, Patric and Spietz, Peter and Spr{\"o}witz, Tom and Sznajder, Maciej and Tardivel, Simon and T{\´o}th, Norbert and Wejmo, Elisabet and Wolff, Friederike and Ziach, Christian}, title = {Small spacecraft based multiple near-earth asteroid rendezvous and landing with near-term solar sails and 'Now-Term 'technologies}, series = {69 th International Astronautical Congress (IAC)}, booktitle = {69 th International Astronautical Congress (IAC)}, pages = {1 -- 18}, year = {2018}, abstract = {Physical interaction with small solar system bodies (SSSB) is the next step in planetary science, planetary in-situ resource utilization (ISRU), and planetary defense (PD). It requires a broader understanding of the surface properties of the target objects, with particular interest focused on those near Earth. Knowledge of composition, multi-scale surface structure, thermal response, and interior structure is required to design, validate and operate missions addressing these three fields. The current level of understanding is occasionally simplified into the phrase, "If you've seen one asteroid, you've seen one asteroid", meaning that the in-situ characterization of SSSBs has yet to cross the threshold towards a robust and stable scheme of classification. This would enable generic features in spacecraft design, particularly for ISRU and science missions. Currently, it is necessary to characterize any potential target object sufficiently by a dedicated pre-cursor mission to design the mission which then interacts with the object in a complex fashion. To open up strategic approaches, much broader in-depth characterization of potential target objects would be highly desirable. In SSSB science missions, MASCOT-like nano-landers and instrument carriers which integrate at the instrument level to their mothership have met interest. By its size, MASCOT is compatible with small interplanetary missions. The DLR-ESTEC Gossamer Roadmap Science Working Groups' studies identified Multiple Near-Earth asteroid (NEA) Rendezvous (MNR) as one of the space science missions only feasible with solar sail propulsion. The Solar Polar Orbiter (SPO) study showed the ability to access any inclination, theDisplaced-L1 (DL1) mission operates close to Earth, where objects of interest to PD and for ISRU reside. Other studies outline the unique capability of solar sails to provide access to all SSSB, at least within the orbit of Jupiter, and significant progress has been made to explore the performance envelope of near-term solar sails for MNR. However, it is difficult for sailcraft to interact physically with a SSSB. We expand and extend the philosophy of the recently qualified DLR Gossamer solar sail deployment technology using efficient multiple sub-spacecraft integration to also include landers for one-way in-situ investigations and sample-return missions by synergetic integration and operation of sail and lander. The MASCOT design concept and its characteristic features have created an ideal counterpart for thisand has already been adapted to the needs of the AIM spacecraft, former part of the NASA-ESA AIDA missionDesigning the 69th International Astronautical Congress (IAC), Bremen, Germany, 1-5 October 2018. IAC-18-F1.2.3 Page 2 of 17 combined spacecraft for piggy-back launch accommodation enables low-cost massively parallel access to the NEA population.}, language = {en} } @inproceedings{GoldmannBraunsteinHeinrichetal.2015, author = {Goldmann, Jan-Peter and Braunstein, Bjoern and Heinrich, Kai and Sanno, Maximilian and St{\"a}udle, Benjamin and Ritzdorf, Wolfgang and Br{\"u}ggemann, Gert-Peter and Albracht, Kirsten}, title = {Joint work of the take-off leg during elite high jump}, series = {Proceedings of the 33th International Conference on Biomechanics in Sports (ISBS)}, booktitle = {Proceedings of the 33th International Conference on Biomechanics in Sports (ISBS)}, pages = {3 S.}, year = {2015}, language = {en} } @inproceedings{GehlerOberBloebaumDachwald2009, author = {Gehler, M. and Ober-Bl{\"o}baum, S. and Dachwald, Bernd}, title = {Application of discrete mechanics and optimal control to spacecraft in non-keplerian motion around small solar system bodies}, series = {Procceedings of the 60th International Astronautical Congress}, booktitle = {Procceedings of the 60th International Astronautical Congress}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {978-161567908-9}, pages = {1360 -- 1371}, year = {2009}, abstract = {Prolonged operations close to small solar system bodies require a sophisticated control logic to minimize propellant mass and maximize operational efficiency. A control logic based on Discrete Mechanics and Optimal Control (DMOC) is proposed and applied to both conventionally propelled and solar sail spacecraft operating at an arbitrarily shaped asteroid in the class of Itokawa. As an example, stand-off inertial hovering is considered, recently identified as a challenging part of the Marco Polo mission. The approach is easily extended to stand-off orbits. We show that DMOC is applicable to spacecraft control at small objects, in particular with regard to the fact that the changes in gravity are exploited by the algorithm to optimally control the spacecraft position. Furthermore, we provide some remarks on promising developments.}, language = {en} } @inproceedings{FrotscherStaat2015, author = {Frotscher, Ralf and Staat, Manfred}, title = {An electromechanical model for cardiac tissue constructs}, series = {Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen, 20.07.2015 - 23.07.2015 / ed.: Stefanie Elgeti ; Jaan-Willem Simon}, booktitle = {Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen, 20.07.2015 - 23.07.2015 / ed.: Stefanie Elgeti ; Jaan-Willem Simon}, publisher = {RWTH Aachen University}, address = {Aachen}, organization = {ECCOMAS Young Investigators Conference <3, 2015, Aachen>}, pages = {1 -- 4}, year = {2015}, language = {en} } @inproceedings{FrotscherStaat2015, author = {Frotscher, Ralf and Staat, Manfred}, title = {Homogenization of a cardiac tissue construct}, series = {CMBE15 : 4th International Conference on Computational \& Mathematical Biomedical Engineering ; 29th June - 1st July 2015 ; {\´E}cole Normale Sup{\´e}rieure de Cachan ; Cachan (Paris), France}, booktitle = {CMBE15 : 4th International Conference on Computational \& Mathematical Biomedical Engineering ; 29th June - 1st July 2015 ; {\´E}cole Normale Sup{\´e}rieure de Cachan ; Cachan (Paris), France}, editor = {Nithiarasu, Perumal}, publisher = {CMBE}, address = {[s.l.]}, issn = {2227-9385}, pages = {645 -- 648}, year = {2015}, language = {en} } @inproceedings{FrotscherRaatschenStaat2012, author = {Frotscher, Ralf and Raatschen, Hans-J{\"u}rgen and Staat, Manfred}, title = {Application of an edge-based smoothed finite element method on geometrically non-linear plates of non-linear material}, series = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)}, booktitle = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)}, editor = {Eberhardsteiner, J.}, year = {2012}, language = {en} } @inproceedings{FrotscherRaatschenStaat2012, author = {Frotscher, Ralf and Raatschen, Hans-J{\"u}rgen and Staat, Manfred}, title = {Effectiveness of the edge-based smoothed finite element method applied to soft biological tissues}, series = {ESMC-2012 - 8th European Solid Mechanics Conference, Graz, Austria, July 9-13, 2012}, booktitle = {ESMC-2012 - 8th European Solid Mechanics Conference, Graz, Austria, July 9-13, 2012}, editor = {Holzapfel, Gerhard A.}, publisher = {Verlag d. Technischen Universit{\"a}t Graz}, address = {Graz}, isbn = {978-3-85125-223-1}, year = {2012}, language = {en} } @inproceedings{FrotscherKochRaatschenetal.2014, author = {Frotscher, Ralf and Koch, Jan-Peter and Raatschen, Hans-J{\"u}rgen and Staat, Manfred}, title = {Evaluation of a computational model for drug action on cardiac tissue}, series = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20 - 25, 2014, Barcelona}, booktitle = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20 - 25, 2014, Barcelona}, editor = {Onate, E.}, organization = {World Congress on Computational Mechanics <11, 2014, Barcelona>}, pages = {1 -- 12}, year = {2014}, language = {en} } @inproceedings{FrotscherGossmannTemizArtmannetal.2013, author = {Frotscher, Ralf and Goßmann, Matthias and Temiz Artmann, Ayseg{\"u}l and Staat, Manfred}, title = {Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM}, series = {1st International Conference "Shell and Membrane Theories in Mechanics and Biology: From Macro- to Nanoscale Structures", Minsk, Belarus, Sept. 16-20, 2013}, booktitle = {1st International Conference "Shell and Membrane Theories in Mechanics and Biology: From Macro- to Nanoscale Structures", Minsk, Belarus, Sept. 16-20, 2013}, publisher = {Verl. d. Weißruss. Staatl. Univ.}, address = {Minsk}, organization = {International Conference Shell and Membrane Theories in Mechanics and Biology: From Macro- to Nanoscale Structures <1, 2013, Minsk>}, isbn = {978-985-553-135-8}, pages = {165 -- 167}, year = {2013}, language = {en} } @inproceedings{FrotscherDuongStaat2015, author = {Frotscher, Ralf and Duong, Minh Tuan and Staat, Manfred}, title = {Simulating beating cardiomyocytes with electromechanical coupling}, series = {II. International Conference on Biomedical Technology : 28-30 October 2015 Hannover, Germany / T. Lenarz, P. Wriggers (Eds.)}, booktitle = {II. International Conference on Biomedical Technology : 28-30 October 2015 Hannover, Germany / T. Lenarz, P. Wriggers (Eds.)}, organization = {International Conference on Biomedical Technology <2, 2015, Hannover>}, pages = {1 -- 2}, year = {2015}, language = {en} } @inproceedings{ElBashirDigel2009, author = {ElBashir, Rasha and Digel, Ilya}, title = {Effect of nitric oxide gas on hydrogels : [abstract]}, year = {2009}, abstract = {The results support our theory that the NO gas has an influence in increasing the translational diffusion of hydrogels and it accelerates the melting process of the gels.}, subject = {Stickstoffmonoxid}, language = {en} } @inproceedings{DupratDachwaldHilchenbachetal.2013, author = {Duprat, J. and Dachwald, Bernd and Hilchenbach, M. and Engrand, Cecile and Espe, C. and Feldmann, M. and Francke, G. and G{\"o}r{\"o}g, Mark and L{\"u}sing, N. and Langenhorst, Falko}, title = {The MARVIN project: a micrometeorite harvester in Antarctic snow}, series = {44th Lunar and Planetary Science Conference}, booktitle = {44th Lunar and Planetary Science Conference}, year = {2013}, abstract = {MARVIN is an automated drilling and melting probe dedicated to collect pristine interplanetary dust particles (micrometeorites) from central Antarctica snow.}, language = {en} } @inproceedings{DuongStaat2014, author = {Duong, Minh Tuan and Staat, Manfred}, title = {A face-based smoothed finite element method for hyperelastic models and tissue growth}, series = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20-25, 2014, Barcelona}, booktitle = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20-25, 2014, Barcelona}, editor = {Onate, E.}, organization = {World Congress on Computational Mechanics <11, 2014, Barcelona>}, pages = {1 -- 12}, year = {2014}, language = {en} } @inproceedings{DuongNguyenStaat2012, author = {Duong, Minh Tuan and Nguyen, Nhu Huynh and Staat, Manfred}, title = {Numerical stability enhancement of modeling hyperelastic materials}, series = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)}, booktitle = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)}, editor = {Eberhardsteiner, J.}, year = {2012}, language = {en} } @inproceedings{DuongNguyenStaat2012, author = {Duong, Minh Tuan and Nguyen, Nhu Hunyh and Staat, Manfred}, title = {Finite Element Implementation of a 3D Fung-type Model}, series = {ESMC-2012 - 8th European Solid Mechanics Conference, Graz, Austria, July 9-13, 2012}, booktitle = {ESMC-2012 - 8th European Solid Mechanics Conference, Graz, Austria, July 9-13, 2012}, publisher = {Verlag d. Technischen Universit{\"a}t Graz}, address = {Graz}, isbn = {978-3-85125-223-1}, year = {2012}, language = {en} } @inproceedings{DuongNguyenStaat2015, author = {Duong, Minh Tuan and Nguyen, N. H. and Staat, Manfred}, title = {Modeling and simulation of a growing mass by the Smoothed Finite Element Method (SFEM)}, series = {Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen, Germany, 20.07.2015 - 23.07.2015 / ed.: Stefanie Elgeti ; Jaan-Willem Simon}, booktitle = {Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen, Germany, 20.07.2015 - 23.07.2015 / ed.: Stefanie Elgeti ; Jaan-Willem Simon}, publisher = {RWTH Aachen University}, address = {Aachen}, organization = {ECCOMAS Young Investigators Conference <3, 2015, Aachen>}, pages = {1 -- 4}, year = {2015}, language = {en} } @inproceedings{DuongJungFrotscheretal.2016, author = {Duong, Minh Tuan and Jung, Alexander and Frotscher, Ralf and Staat, Manfred}, title = {A 3D electromechanical FEM-based model for cardiac tissue}, series = {ECCOMAS Congress 2016, VII European Congress on Computational Methods in Applied Sciences and Engineering. Crete Island, Greece, 5-10 June 2016}, booktitle = {ECCOMAS Congress 2016, VII European Congress on Computational Methods in Applied Sciences and Engineering. Crete Island, Greece, 5-10 June 2016}, editor = {Papadrakakis, M.}, pages = {13 S.}, year = {2016}, language = {en} }