@article{ZhubanovaAknazarovMansurovetal.2010, author = {Zhubanova, Azhar A. and Aknazarov, S. K. and Mansurov, Zulkhair and Digel, Ilya and Kozhalakova, A. A. and Akimbekov, Nuraly Shardarbekovich and O'Heras, Carlos and Tazhibayeva, S. and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l}, title = {Adsorption of bacterial Lipopolysaccharides and blood plasma proteins on modified carbonized materials}, year = {2010}, abstract = {Bacterial lipopolysaccharides (endotoxins) show strong biological effects at very low concentrations in human beings and many animals when entering the blood stream. These include affecting structure and function of organs and cells, changing metabolic functions, raising body temperature, triggering the coagulation cascade, modifying hemodynamics and causing septic shock. Because of this toxicity, the removal of even minute amounts is essential for safe parenteral administration of drugs and also for septic shock patients' care. The absence of a general method for endotoxin removal from liquid interfaces urgently requires finding new methods and materials to overcome this gap. Nanostructured carbonized plant parts is a promising material that showed good adsorption properties due to its vast pore network and high surface area. The aim of this study was comparative measurement of endotoxin- and blood proteins-related adsorption rate and adsorption capacity for different carboneous materials produced at different temperatures and under different surface modifications. As a main surface modificator, positively cbarged polymer, polyethileneimine (PEl) was used. Activated carbon materials showed good adsorption properties for LPS and some proteins used in the experiments. During the batch experiments, several techniques (dust removal, autoclaving) were used and optimized for improving the material's adsorption behavior. Also, with the results obtained it was possible to differentiate the materials according to their adsorption capacity and kinetic characteristics. Modification of the surface apparently has not affected hemoglobin binding to the adsorbent's surface. Obtained adsorption isotherms can be used as a powerful tool for designing of future column-based setups for blood purification from LPS, which is especially important for septic shock treatment.}, subject = {Kohlenstofffaser}, language = {en} } @article{UllrichGrottkeRossaintetal.2010, author = {Ullrich, Sebastian and Grottke, Oliver and Rossaint, Rolf and Staat, Manfred and Deserno, Thomas M. and Kuhlen, Torsten}, title = {Virtual Needle Simulation with Haptics for Regional Anaesthesia}, pages = {1 -- 3}, year = {2010}, language = {en} } @article{SiqueiraBaeckerPoghossianetal.2010, author = {Siqueira, Jos{\´e} R. Jr. and B{\"a}cker, Matthias and Poghossian, Arshak and Zucolotto, Valtencir and Oliveira, Osvaldo N. Jr. and Sch{\"o}ning, Michael Josef}, title = {Associating biosensing properties with the morphological structure of multilayers containing carbon nanotubes on field-effect devices}, series = {Physica status solidi (a). 207 (2010), H. 4}, journal = {Physica status solidi (a). 207 (2010), H. 4}, isbn = {1862-6300}, pages = {781 -- 786}, year = {2010}, language = {en} } @article{SchoeningKirchnerNgetal.2010, author = {Sch{\"o}ning, Michael Josef and Kirchner, Patrick and Ng, Yue Ann and Spelthahn, Heiko and Schneider, Andreas and Henkel, Hartmut and Friedrich, Peter and Kolstad, Jens and Berger, J{\"o}rg and Keusgen, Michael}, title = {Gas sensor investigation based on a catalytically activated thin-film thermopile for H2O2 detection}, series = {Physica Status Solidi (A). 207 (2010), H. 4}, journal = {Physica Status Solidi (A). 207 (2010), H. 4}, isbn = {1862-6300}, pages = {787 -- 792}, year = {2010}, language = {en} } @article{TurekHeidenGuoetal.2010, author = {Turek, Monik and Heiden, Wolfgang and Guo, Sharon and Riesen, Alfred and Schubert, J{\"u}rgen and Zander, Willi and Kr{\"u}ger, Peter and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Simultaneous detection of cyanide and heavy metals for environmental analysis by means of µISEs}, series = {Physica Status Solidi (A). 207 (2010), H. 4}, journal = {Physica Status Solidi (A). 207 (2010), H. 4}, isbn = {1862-6300}, pages = {817 -- 823}, year = {2010}, language = {en} } @article{BuniatyanAbouzarMartirosyanetal.2010, author = {Buniatyan, Vahe V. and Abouzar, Maryam H. and Martirosyan, Norayr W. and Schubert, J{\"u}rgen and Gevorgian, Spartak and Sch{\"o}ning, Michael Josef and Poghossian, Arshak}, title = {pH-sensitive properties of barium strontium titanate (BST) thin films prepared by pulsed laser deposition technique}, series = {Physica Status Solidi (A). 207 (2010), H. 4}, journal = {Physica Status Solidi (A). 207 (2010), H. 4}, isbn = {1862-6300}, pages = {824 -- 830}, year = {2010}, language = {en} } @article{AbouzarPoghossianSiqueiraetal.2010, author = {Abouzar, Maryam H. and Poghossian, Arshak and Siqueira, Jos{\´e} R. Jr. and Oliveira, Osvaldo N. Jr. and Moritz, Werner and Sch{\"o}ning, Michael Josef}, title = {Capacitive electrolyte-insulator-semiconductor structures functionalised with a polyelectrolyte/enzyme multilayer: New strategy for enhanced field-effect biosensing}, series = {Physica Status Solidi (A). 207 (2010), H. 4}, journal = {Physica Status Solidi (A). 207 (2010), H. 4}, isbn = {1862-6300}, pages = {884 -- 890}, year = {2010}, language = {en} } @article{ReisertHenkelSchneideretal.2010, author = {Reisert, Steffen and Henkel, Hartmut and Schneider, Andreas and Sch{\"a}fer, Daniel and Friedrich, Peter and Berger, J{\"o}rg and Sch{\"o}ning, Michael Josef}, title = {Development of a handheld sensor system for the online measurement of hydrogen peroxide in aseptic filling systems}, series = {Physica Status Solidi (A). 207 (2010), H. 4}, journal = {Physica Status Solidi (A). 207 (2010), H. 4}, isbn = {1862-6300}, pages = {913 -- 918}, year = {2010}, language = {en} } @article{BegingMlynekHataihimakuletal.2010, author = {Beging, Stefan and Mlynek, Daniela and Hataihimakul, Sudkanung and Poghossian, Arshak and Baldsiefen, Gerhard and Busch, Heinz and Laube, Norbert and Kleinen, Lisa and Sch{\"o}ning, Michael Josef}, title = {Field-effect calcium sensor for the determination of the risk of urinary stone formation}, series = {Sensors and Actuators B: Chemical. 144 (2010), H. 2}, journal = {Sensors and Actuators B: Chemical. 144 (2010), H. 2}, pages = {374 -- 379}, year = {2010}, language = {en} } @article{MiyamotoSugawaraKanohetal.2010, author = {Miyamoto, Ko-ichiro and Sugawara, Yuri and Kanoh, Shin´ichiro and Yoshinobu, Tatsuo and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {Image correction method for the chemical imaging sensor}, series = {Sensors and Actuators B: Chemical. 144 (2010), H. 2}, journal = {Sensors and Actuators B: Chemical. 144 (2010), H. 2}, pages = {344 -- 348}, year = {2010}, language = {en} } @article{BaeckerPoghossianAbouzaretal.2010, author = {B{\"a}cker, Matthias and Poghossian, Arshak and Abouzar, Maryam H. and Wenmackers, Sylvia and Janssens, Stoffel D. and Haenen, Ken and Wagner, Patrick and Sch{\"o}ning, Michael Josef}, title = {Capacitive field-effect (bio-)chemical sensors based on nanocrystalline diamond films}, series = {Diamond Electronics and Bioelectronics — Fundamentals to Applications III, edited by P. Bergonzo, [u.a.]}, journal = {Diamond Electronics and Bioelectronics — Fundamentals to Applications III, edited by P. Bergonzo, [u.a.]}, pages = {1 -- 6}, year = {2010}, language = {en} } @article{NguyenRaatschenStaat2010, author = {Nguyen, N.-H. and Raatschen, Hans-J{\"u}rgen and Staat, Manfred}, title = {A hyperelastic model of biological tissue materials in tubular organs}, pages = {1 -- 12}, year = {2010}, language = {en} } @article{PhamVuTranetal.2010, author = {Pham, Phu Tinh and Vu, Khoi Duc and Tran, Thanh Ngoc and Staat, Manfred}, title = {A primal-dual algorithm for shakedown analysis of elastic-plastic bounded linearly kinematic hardening bodies}, pages = {1 -- 7}, year = {2010}, language = {en} } @article{TranStaat2010, author = {Tran, Thanh Ngoc and Staat, Manfred}, title = {Shakedown analysis of two dimensional structures by an edge-based smoothed finite element method}, pages = {1 -- 7}, year = {2010}, language = {en} } @article{AlexopoulosHoffschmidt2010, author = {Alexopoulos, Spiros and Hoffschmidt, Bernhard}, title = {Solar tower power plant in Germany and future perspectives of the development of the technology in Greece and Cyprus}, series = {Renewable Energy . 35 (2010), H. 7}, journal = {Renewable Energy . 35 (2010), H. 7}, isbn = {0960-1481}, pages = {1352 -- 1356}, year = {2010}, language = {en} } @article{BalakrishnanAndreiSelmerSelmeretal.2010, author = {Balakrishnan, Karthikeyan and Andrei-Selmer, Luminita-Cornelia and Selmer, Thorsten and Bacher, Michael and Dodel, Richard}, title = {Comparison of Intravenous Immunoglobulins for Naturally Occurring Autoantibodies against Amyloid-β}, series = {Journal of Alzheimer's Disease}, volume = {20}, journal = {Journal of Alzheimer's Disease}, number = {1}, isbn = {1387-2877}, pages = {135 -- 143}, year = {2010}, language = {en} } @article{SiqueiraMakiPaulovichetal.2010, author = {Siqueira, Jose R. and Maki, Rafael M. and Paulovich, Fernando V. and Werner, Frederik and Poghossian, Arshak and Oliveira, Maria C. F. de and Zucolotto, Valtencir and Oliveira, Osvaldo N. Jr. and Sch{\"o}ning, Michael Josef}, title = {Use of Information Visualization Methods Eliminating Cross Talk in Multiple Sensing Units Investigated for a Light-Addressable Potentiometric Sensor}, series = {Analytical Chemistry (2010)}, journal = {Analytical Chemistry (2010)}, isbn = {0003-2700}, pages = {61 -- 65}, year = {2010}, language = {en} } @article{GrottkeBraunschweigPhilippenetal.2010, author = {Grottke, O. and Braunschweig, T. and Philippen, B. and Gatzweiler, Karl-Heinz and Gronloh, N. and Staat, Manfred and Rossaint, R. and Tolba, R.}, title = {A New Model for Blunt Liver Injuries in the Swine}, series = {European Surgical Research. 44 (2010), H. 2}, journal = {European Surgical Research. 44 (2010), H. 2}, isbn = {1421-9921}, pages = {65 -- 73}, year = {2010}, language = {en} } @article{StaatSponagelNguyen2010, author = {Staat, Manfred and Sponagel, Stefan and Nguyen, Nhu Huynh}, title = {Experiment and material model for soft tissue materials}, series = {Constitutive models for rubber VI : proceedings of the sixth European Conference on Constitutive Models for Rubber, Dresden, Germany, 7 - 10 September 2009 / eds. Gert Heinrich ...}, journal = {Constitutive models for rubber VI : proceedings of the sixth European Conference on Constitutive Models for Rubber, Dresden, Germany, 7 - 10 September 2009 / eds. Gert Heinrich ...}, publisher = {CRC Press}, address = {Boca Raton [u.a.]}, isbn = {978-0-415-56327-7}, pages = {465 -- 470}, year = {2010}, language = {en} } @article{ScholzLeyDachwaldetal.2010, author = {Scholz, A. and Ley, Wilfried and Dachwald, Bernd and Miau, J. J. and Juang, J. C.}, title = {Flight results of the COMPASS-1 picosatellite mission}, series = {Acta Astronautica. 67 (2010), H. 9-10}, journal = {Acta Astronautica. 67 (2010), H. 9-10}, isbn = {0094-5765}, pages = {1289 -- 1298}, year = {2010}, language = {en} } @article{FredebeulKreinKnoben2010, author = {Fredebeul-Krein, Markus and Knoben, Werner}, title = {Long term risk sharing contracts as an approach to establish public-private partnerships for investment into next generation access networks}, series = {Telecommunications Policy}, volume = {34}, journal = {Telecommunications Policy}, number = {9}, isbn = {0308-5961}, pages = {528 -- 539}, year = {2010}, language = {en} } @article{HirschfeldLustfeldReisseletal.2010, author = {Hirschfeld, J. A. and Lustfeld, H. and Reißel, Martin and Steffen, B.}, title = {A novel scheme for precise diagnostics and effective stabilization of currents in a fuel cell stack}, series = {International Journal of Energy Research. 34 (2010), H. 3}, journal = {International Journal of Energy Research. 34 (2010), H. 3}, isbn = {0363-907X}, pages = {293 -- 301}, year = {2010}, language = {en} } @article{HirschfeldLustfeldReisseletal.2010, author = {Hirschfeld, J. A. and Lustfeld, H. and Reißel, Martin and Steffen, B.}, title = {Tomographic diagnostics of current distributions in a fuel cell stack}, series = {International Journal of Energy Research}, volume = {34}, journal = {International Journal of Energy Research}, number = {3}, isbn = {0363-907X}, pages = {284 -- 292}, year = {2010}, language = {en} } @article{GerhardsBelloumBerretzetal.2010, author = {Gerhards, M. and Belloum, A. and Berretz, F. and Sander, Volker and Skorupa, S.}, title = {A history-tracing XML-based provenance framework for workflows}, isbn = {978-1-4244-8989-3}, pages = {1 -- 10}, year = {2010}, language = {en} } @article{BouquegneauKernRousseau2010, author = {Bouquegneau, Christian and Kern, Alexander and Rousseau, Alain}, title = {Lightning safety guidelines}, pages = {1 -- 6}, year = {2010}, language = {en} } @article{KernFrentzelBehrens2010, author = {Kern, Alexander and Frentzel, Ralf and Behrens, J{\"o}rg}, title = {Simulation of the transient voltages in the auxiliary power network of a large power plant in case of a direct lightning strike to the high-voltage overhead transmission line}, pages = {749-1 -- 749-7}, year = {2010}, language = {en} } @article{KernKloetersPferdemenges2010, author = {Kern, Alexander and Kl{\"o}ters, Georg and Pferdemenges, J{\"o}rg}, title = {Optimised protection against lightning for the signalling and safety systems of level crossings on non-electrified railway lines}, series = {RTR : European Rail Technology Review}, volume = {50}, journal = {RTR : European Rail Technology Review}, number = {2}, isbn = {0079-9548}, year = {2010}, language = {en} } @article{AbouzarPedrazaSchoeningetal.2010, author = {Abouzar, Maryam H. and Pedraza, A. M. and Sch{\"o}ning, Michael Josef and Poghossian, Arshak}, title = {Label-free DNA hybridization and denaturation detection by means of field-effect nanoplate SOI capacitors functionalized with gold nanoparticles}, series = {Procedia Engineering. 5 (2010)}, journal = {Procedia Engineering. 5 (2010)}, isbn = {1877-7058}, pages = {918 -- 921}, year = {2010}, language = {en} } @article{BerretzSkorupaSanderetal.2010, author = {Berretz, F. and Skorupa, S. and Sander, Volker and Belloum, A.}, title = {Towards an actor-driven workflow management system for grids}, series = {International Symposium on Collaborative Technologies and Systems (CTS), 2010 : 17 - 21 May 2010, Chicago, Illinois, USA / IEEE}, journal = {International Symposium on Collaborative Technologies and Systems (CTS), 2010 : 17 - 21 May 2010, Chicago, Illinois, USA / IEEE}, publisher = {IEEE}, address = {Piscataway, NJ}, isbn = {978-1-4244-6619-1}, pages = {611 -- 616}, year = {2010}, language = {en} } @article{KernSchelthoffMathieu2010, author = {Kern, Alexander and Schelthoff, Christof and Mathieu, Moritz}, title = {Probability of lightning strikes to air-terminations of structures using the electro-geometrical model theory and the statistics of lightning current parameters}, pages = {750-1 -- 750-8}, year = {2010}, language = {en} } @article{WagnerWernerMiyamotoetal.2010, author = {Wagner, Torsten and Werner, Frederik and Miyamoto, Ko-ichiro and Ackermann, Hans-Josef and Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef}, title = {FPGA-based LAPS device for the flexible design of sensing sites on functional interfaces}, series = {Physica Status Solidi (A). 207 (2010), H. 4}, journal = {Physica Status Solidi (A). 207 (2010), H. 4}, isbn = {1862-6300}, pages = {844 -- 849}, year = {2010}, language = {en} } @article{BlomeChiconeHehletal.2010, author = {Blome, Hans-Joachim and Chicone, Carmen and Hehl, Friedrich W. and Mashhoon, Bahram}, title = {Nonlocal modification of Newtonian gravity}, series = {Physical Review D}, volume = {81}, journal = {Physical Review D}, number = {6}, isbn = {0556-2821}, pages = {065020}, year = {2010}, language = {en} } @article{SpelthahnSchaffrathCoppeetal.2010, author = {Spelthahn, Heiko and Schaffrath, Sophie and Coppe, Thomas and Rufi, Frederic and Sch{\"o}ning, Michael Josef}, title = {Development of an electrolyte-insulator-semiconductor (EIS) based capacitive heavy metal sensor for the detection of Pb2+ und Cd2+ ions}, series = {Physica status solidi (a) : applications and material science. 207 (2010), H. 4}, journal = {Physica status solidi (a) : applications and material science. 207 (2010), H. 4}, isbn = {1862-6300}, pages = {930 -- 934}, year = {2010}, language = {en} } @article{WagnerMiyamotoSchoeningetal.2010, author = {Wagner, Torsten and Miyamoto, Ko-ichiro and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Novel combination of digital light processing (DLP) and light-addressable potentiometric sensors (LAPS) for flexible chemical imaging}, series = {Procedia Engineering. 5 (2010)}, journal = {Procedia Engineering. 5 (2010)}, isbn = {1877-7058}, pages = {520 -- 523}, year = {2010}, language = {en} } @article{KirchnerOberlaenderFriedrichetal.2010, author = {Kirchner, Patrick and Oberl{\"a}nder, Jan and Friedrich, Peter and Rysstad, G. and Berger, J. and Keusgen, M. and Sch{\"o}ning, Michael Josef}, title = {Realization of a calorimetric gas sensor on polyimide foil for applications in aseptic food industry}, series = {Procedia Engineering. 5 (2010)}, journal = {Procedia Engineering. 5 (2010)}, isbn = {1877-7058}, pages = {264 -- 267}, year = {2010}, language = {en} } @article{MiyamotoKanekoMatsuoetal.2010, author = {Miyamoto, Ko-ichiro and Kaneko, Kazumi and Matsuo, Akira and Wagner, Torsten and Kanoh, Shin`ichiro and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Miniaturized chemical imaging sensor system using an OLED display panel}, series = {Procedia Engineering. 5 (2010)}, journal = {Procedia Engineering. 5 (2010)}, isbn = {1877-7058}, pages = {516 -- 519}, year = {2010}, language = {en} } @article{BohrnStuetzFleischeretal.2010, author = {Bohrn, U. and St{\"u}tz, E. and Fleischer, M. and Sch{\"o}ning, Michael Josef}, title = {Real-time detection of CO by eukaryotic cells}, series = {Procedia Engineering. 5 (2010)}, journal = {Procedia Engineering. 5 (2010)}, isbn = {1877-7058}, pages = {17 -- 20}, year = {2010}, language = {en} } @article{SrivastavaSinghAggarwaletal.2010, author = {Srivastava, A. and Singh, V. and Aggarwal, P. and Schneeweiss, F. and Scherer, Ulrich W. and Friedrich, W.}, title = {Optical studies of insulating polymers for radiation dose monitoring}, series = {Indian Journal of Pure \& Applied Physics}, volume = {48}, journal = {Indian Journal of Pure \& Applied Physics}, number = {11}, isbn = {0019-5596}, pages = {782 -- 786}, year = {2010}, language = {en} } @article{GebhardtSchmidtHoetteretal.2010, author = {Gebhardt, Andreas and Schmidt, Frank-Michael and H{\"o}tter, Jan-Steffen and Sokalla, Wolfgang and Sokalla, Patrick}, title = {Additive Manufacturing by selective laser melting the realizer desktop machine and its application for the dental industry}, series = {Physics Procedia}, volume = {5}, journal = {Physics Procedia}, number = {2}, isbn = {1875-3892}, pages = {543 -- 549}, year = {2010}, language = {en} } @article{GeimerSauerbornHoffschmidtetal.2010, author = {Geimer, Konstantin and Sauerborn, Markus and Hoffschmidt, Bernhard and Schmitz, Mark and G{\"o}ttsche, Joachim}, title = {Test Facility for Absorber Specimens of Solar Tower Power Plants}, series = {Advances in Science and Technology. 74 (2010)}, journal = {Advances in Science and Technology. 74 (2010)}, pages = {266 -- 271}, year = {2010}, language = {en} } @article{MaiwaldDachwald2010, author = {Maiwald, Volker and Dachwald, Bernd}, title = {Mission Design for a Multiple-Rendezvous Mission to Jupiter's Trojans}, pages = {3}, year = {2010}, language = {en} } @article{BehbahaniProbstMaietal.2010, author = {Behbahani, Mehdi and Probst, M. and Mai, A. and Tran, L. and Vonderstein, K. and Keschenau, P. and Linde, T. and Steinseifer, U. and Behr, M. and Mottaghy, K.}, title = {The influence of high shear on thrombosis and hemolysis in artificial organs}, series = {Artificial Organs}, volume = {33}, journal = {Artificial Organs}, number = {7}, isbn = {0391-3988}, pages = {426 -- 426}, year = {2010}, language = {en} } @article{JansenBehbahaniLaumenetal.2010, author = {Jansen, Sebastian and Behbahani, Mehdi and Laumen, Marco and Kaufmann, Tim and Hormes, Marcus and Schmitz-Rode, Thomas and Behr, Marek and Steinseifer, Ulrich}, title = {3D Stereo-PIV Validation for CFD-Simulation of Steady Flow through the Human Aorta using Rapid-Prototyping techniques}, year = {2010}, language = {en} } @article{BoernerFunkeHendricketal.2010, author = {B{\"o}rner, Sebastian and Funke, Harald and Hendrick, P. and Recker, E.}, title = {Control system modifications for a hydrogen fuelled gas-turbine}, series = {ISROMAC 13, 13th International Symposium on Transport Phenomena and Dynamics of Rotating Machinery, Honolulu, HI, US, Apr 4-7, 2010}, journal = {ISROMAC 13, 13th International Symposium on Transport Phenomena and Dynamics of Rotating Machinery, Honolulu, HI, US, Apr 4-7, 2010}, publisher = {Curran}, address = {Red Hook, NY}, isbn = {978-1-617-38848-4}, pages = {665 -- 670}, year = {2010}, language = {en} } @article{BehbahaniMaiBergmannetal.2010, author = {Behbahani, Mehdi and Mai, A. and Bergmann, B. and Waluga, C. and Behr, M. and Tran, L. and Vonderstein, K. and Mottaghy, K.}, title = {Modeling and Numerical Simulation of Blood Damage}, year = {2010}, language = {en} } @article{BehbahaniMaiWalugaetal.2010, author = {Behbahani, Mehdi and Mai, A. and Waluga, C. and Bergmann, B. and Tran, L. and Vonderstein, K. and Behr, M. and Mottaghy, K.}, title = {Numerical Modeling of Flow-Related Thrombus Formation under Physiological and Non-Physiological Flow Conditions}, series = {Acta Physiologica}, volume = {198}, journal = {Acta Physiologica}, number = {Supplement 677}, isbn = {1748-1716}, pages = {185}, year = {2010}, language = {en} } @article{BehbahaniNamWalugaetal.2010, author = {Behbahani, Mehdi and Nam, J. and Waluga, C. and Behr, M. and Pasquali, M. and Mottaghy, K.}, title = {Modeling and Numerical Analysis of Platelet Activation, Adhesion and Aggregation in Artificial Organs}, doi = {10.1097/01.mat.0000369377.65122.a3}, year = {2010}, language = {en} } @article{JansenBehbahaniLaumenetal.2010, author = {Jansen, S. V. and Behbahani, Mehdi and Laumen, M. and Kaufmann, T. and Hormes, M. and Behr, M. and Schmitz-Rode, T. and Steinseifer, U.}, title = {Investigation of Steady Flow Through a Realistic Model of the Thoracic Human Aorta Using 3D Stereo PIV and CFD-Simulation}, year = {2010}, language = {en} } @article{NamAroraBehbahanietal.2010, author = {Nam, J. and Arora, D. and Behbahani, Mehdi and Probst, M. and Benkowski, R. and Behr, M. and Pasquali, M.}, title = {New computational method in hemolysis analysis for artificial heart pump}, year = {2010}, language = {en} } @article{BehbahaniProbstMaietal.2010, author = {Behbahani, Mehdi and Probst, M. and Mai, A. and Behr, M. and Tran, L. and Vonderstein, K. and Mottaghy, K.}, title = {Numerical Prediction of Blood Damage in Biomedical Devices}, year = {2010}, language = {en} } @article{ProbstBehbahaniBorrmannetal.2010, author = {Probst, M. and Behbahani, Mehdi and Borrmann, E. and Elgeti, S. and Nicolai, M. and Behr, M.}, title = {Hemodynamic Modeling for Numerical Analysis and Design of Medical Devices}, year = {2010}, language = {en} } @article{Hillgaertner2010, author = {Hillg{\"a}rtner, Michael}, title = {Normative Regulations}, series = {ECPE Cluster Seminar EMC in Hybrid and Electric Vehicles : 18 May 2010, Fraunhofer Institute Erlangen}, journal = {ECPE Cluster Seminar EMC in Hybrid and Electric Vehicles : 18 May 2010, Fraunhofer Institute Erlangen}, publisher = {European Center for Power Electronics}, address = {N{\"u}rnberg}, pages = {1 CD-ROM}, year = {2010}, language = {en} } @article{GoettscheHoffschmidtSchmitzetal.2010, author = {G{\"o}ttsche, Joachim and Hoffschmidt, Bernhard and Schmitz, Stefan and Sauerborn, Markus}, title = {Solar Concentrating Systems Using Small Mirror Arrays}, series = {Journal of solar energy engineering}, volume = {Vol. 132}, journal = {Journal of solar energy engineering}, number = {Iss. 1}, isbn = {0199-6231}, pages = {4 S.}, year = {2010}, language = {en} } @article{FunkeRobinsonHendricketal.2010, author = {Funke, Harald and Robinson, A. E. and Hendrick, P. and Wagemakers, R.}, title = {Design and Testing of a Micromix Combustor With Recuperative Wall Cooling for a Hydrogen Fuelled µ-Scale Gas Turbine}, series = {Proceedings of the ASME Turbo Expo 2010 : presented at the 2010 ASME Turbo Expo, June 14 - 18, 2010, Glasgow, UK / sponsored by the International Gas Turbine Institute / Vol. 5: Industrial and cogeneration ; microturbines and small turbomachinery ; oil and gas applications ; wind turbine technology}, journal = {Proceedings of the ASME Turbo Expo 2010 : presented at the 2010 ASME Turbo Expo, June 14 - 18, 2010, Glasgow, UK / sponsored by the International Gas Turbine Institute / Vol. 5: Industrial and cogeneration ; microturbines and small turbomachinery ; oil and gas applications ; wind turbine technology}, publisher = {ASME}, address = {New York, NY}, isbn = {978-0-7918-4400-7}, pages = {587 -- 596}, year = {2010}, language = {en} } @article{LeimenaArtmannDachwaldetal.2010, author = {Leimena, W. and Artmann, Gerhard and Dachwald, Bernd and Temiz Artmann, Ayseg{\"u}l and Gossmann, Matthias and Digel, Ilya}, title = {Feasibility of an in-situ microbial decontamination of an ice-melting probe}, series = {Eurasian Chemico-Technological Journal. 12 (2010), H. 2}, journal = {Eurasian Chemico-Technological Journal. 12 (2010), H. 2}, isbn = {1562-3920}, pages = {145 -- 150}, year = {2010}, language = {en} } @article{SchifferFerreinLakemeyer2010, author = {Schiffer, Stefan and Ferrein, Alexander and Lakemeyer, Gerhard}, title = {Proceedings of the Fourth International Conference on Intelligent Robotics and Applications (ICIRA 2011)}, series = {Proceedings of the Fourth International Conference on Intelligent Robotics and Applications (ICIRA 2011)}, journal = {Proceedings of the Fourth International Conference on Intelligent Robotics and Applications (ICIRA 2011)}, pages = {1 -- 10}, year = {2010}, language = {en} } @article{NiemuellerFerreinBecketal.2010, author = {Niem{\"u}ller, Tim and Ferrein, Alexander and Beck, Daniel and Lakemeyer, Gerhard}, title = {Design Principles of the Component-Based Robot Software Framework Fawkes}, series = {Simulation, Modeling, and Programming for Autonomous Robots}, journal = {Simulation, Modeling, and Programming for Autonomous Robots}, pages = {300 -- 311}, year = {2010}, language = {en} } @article{NiemuellerFerreinLakemeyer2010, author = {Niem{\"u}ller, Tim and Ferrein, Alexander and Lakemeyer, Gerhard}, title = {A Lua-based Behavior Engine for Controlling the Humanoid Robot Nao}, series = {RoboCup 2009: Robot Soccer World Cup XIII}, journal = {RoboCup 2009: Robot Soccer World Cup XIII}, pages = {240 -- 251}, year = {2010}, language = {en} } @article{FerreinSiebelSteinbauer2010, author = {Ferrein, Alexander and Siebel, Nils T. and Steinbauer, Gerald}, title = {Hybrid control for autonomous systems — Integrating learning, deliberation and reactive control}, series = {Robotics and Autonomous Systems}, volume = {58}, journal = {Robotics and Autonomous Systems}, number = {9}, isbn = {0921-8890}, pages = {1037 -- 1038}, year = {2010}, language = {en} } @article{FerreinSteinbauer2010, author = {Ferrein, Alexander and Steinbauer, Gerald}, title = {On the Way to High-Level Programming for Resource-Limited Embedded Systems with Golog}, series = {Simulation, Modeling, and Programming for Autonomous Robots}, journal = {Simulation, Modeling, and Programming for Autonomous Robots}, pages = {229 -- 240}, year = {2010}, language = {en} } @article{Ferrein2010, author = {Ferrein, Alexander}, title = {Robot controllers for highly dynamic environments with real-time constraints}, series = {K{\"u}nstliche Intelligenz : KI. 24 (2010), H. 2}, journal = {K{\"u}nstliche Intelligenz : KI. 24 (2010), H. 2}, isbn = {1610-1987}, pages = {175 -- 178}, year = {2010}, language = {en} } @article{RensVarzinczakMeyeretal.2010, author = {Rens, Gavin and Varzinczak, Ivan and Meyer, Thomas and Ferrein, Alexander}, title = {A Logic for Reasoning about Actions and Explicit Observations}, series = {AI 2010: Advances in Artificial Intelligence 23rd Australasian Joint Conference, Adelaide, Australia, December 7-10, 2010. Proceedings}, journal = {AI 2010: Advances in Artificial Intelligence 23rd Australasian Joint Conference, Adelaide, Australia, December 7-10, 2010. Proceedings}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-642-17431-5}, pages = {395 -- 404}, year = {2010}, language = {en} } @article{Ferrein2010, author = {Ferrein, Alexander}, title = {golog.lua: Towards a Non-Prolog Implementation of Golog for Embedded Systems}, pages = {20 -- 28}, year = {2010}, language = {en} } @article{Ferrein2010, author = {Ferrein, Alexander}, title = {golog.lua: Towards a Non-Prolog Implementation of Golog for Embedded Systems}, series = {Cognitive Robotics / Lakemeyer, Gerhard (ed.)}, journal = {Cognitive Robotics / Lakemeyer, Gerhard (ed.)}, pages = {1 -- 15}, year = {2010}, language = {en} } @article{LettiniHavermannGuidettietal.2010, author = {Lettini, Antonio and Havermann, Marc and Guidetti, Marco and Fornaciari, Andrea}, title = {Improved functionalities and energy saving potential on mobile machines combining electronics with flow sharing valve and variable displacement pump}, series = {IFK 7, 7th International Fluid Power Conference, Efficiency through Fluid Power, 7. Internationales Fluidtechnisches Kolloquium, Workshop Proceedings, Vol. 3, Aachen, DE, 22.-24. Mar, 2010}, journal = {IFK 7, 7th International Fluid Power Conference, Efficiency through Fluid Power, 7. Internationales Fluidtechnisches Kolloquium, Workshop Proceedings, Vol. 3, Aachen, DE, 22.-24. Mar, 2010}, publisher = {-}, isbn = {978-3-940565-92-1}, pages = {103 -- 114}, year = {2010}, language = {en} } @article{FunkeBoernerRobinsonetal.2010, author = {Funke, Harald and B{\"o}rner, Sebastian and Robinson, A. and Hendrick, P. and Recker, E.}, title = {Low NOx H2 combustion for industrial gas turbines of various power ranges}, series = {5th International Gas Turbine Conference ETN-IGTC, ETN-2010-42, Brussels, Belgium, October 2010}, journal = {5th International Gas Turbine Conference ETN-IGTC, ETN-2010-42, Brussels, Belgium, October 2010}, year = {2010}, language = {en} } @article{ReckerBosschaertsWagemakersetal.2010, author = {Recker, Elmar and Bosschaerts, Walter and Wagemakers, Rolf and Hendrick, Patrick and Funke, Harald and B{\"o}rner, Sebastian}, title = {Experimental study of a round jet in cross-flow at low momentum ratio}, series = {15th International Symposium on Applications of Laser Techniques to Fluid Mechanics Lisbon, Portugal, 05-08 July, 2010 - 1}, journal = {15th International Symposium on Applications of Laser Techniques to Fluid Mechanics Lisbon, Portugal, 05-08 July, 2010 - 1}, pages = {1 -- 13}, year = {2010}, language = {en} } @article{RibitschKarlBirnerGruenbergeretal.2010, author = {Ribitsch, D. and Karl, W. and Birner-Gruenberger, R. and Gruber, K. and Eiteljoerg, I. and Remler, P. and Wieland, S. and Siegert, Petra and Maurer, Karl-Heinz and Schwab, H.}, title = {C-terminal truncation of a metagenome-derived detergent protease for effective expression in E. coli}, series = {Journal of biotechnology}, volume = {150}, journal = {Journal of biotechnology}, number = {3}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-4863 (E-Journal); 0168-1656 (Print)}, doi = {10.1016/j.jbiotec.2010.09.947}, pages = {408 -- 416}, year = {2010}, abstract = {Recently, a new alkaline protease named HP70 showing highest homology to extracellular serine proteases of Stenotrophomonas maltophilia and Xanthomonas campestris was found in the course of a metagenome screening for detergent proteases (Niehaus et al., submitted for publication). Attempts to efficiently express the enzyme in common expression hosts had failed. This study reports on the realization of overexpression in Escherichia coli after structural modification of HP70. Modelling of HP70 resulted in a two-domain structure, comprising the catalytic domain and a C-terminal domain which includes about 100 amino acids. On the basis of the modelled structure the enzyme was truncated by deletion of most of the C-terminal domain yielding HP70-C477. This structural modification allowed effective expression of active enzyme using E. coli BL21-Gold as the host. Specific activity of HP70-C477 determined with suc-l-Ala-l-Ala-l-Pro-l-Phe-p-nitroanilide as the substrate was 30 ± 5 U/mg compared to 8 ± 1 U/mg of the native enzyme. HP70-C477 was most active at 40 °C and pH 7-11; these conditions are prerequisite for a potential application as detergent enzyme. Determination of kinetic parameters at 40 °C and pH = 9.5 resulted in KM = 0.23 ± 0.01 mM and kcat = 167.5 ± 3.6 s⁻¹. MS-analysis of peptide fragments obtained from incubation of HP70 and HP70-C477 with insulin B indicated that the C-terminal domain influences the cleavage preferences of the enzyme. Washing experiments confirmed the high potential of HP70-C477 as detergent protease.}, language = {en} } @article{BeckerFrauenrathHezeletal.2010, author = {Becker, Meike and Frauenrath, Tobias and Hezel, Fabian and Krombach, Gabriele A. and Kremer, Ute and Koppers, Benedikt and Butenweg, Christoph and Goemmel, Andreas and Utting, Jane F. and Schulz-Menger, Jeanette and Niendorf, Thoralf}, title = {Comparison of left ventricular function assessment using phonocardiogram- and electrocardiogram-triggered 2D SSFP CINE MR imaging at 1.5 T and 3.0 T}, series = {European Radiology}, volume = {20}, journal = {European Radiology}, publisher = {Springer}, address = {Berlin}, issn = {1432-1084 (Onlineausgabe)}, doi = {10.1007/s00330-009-1676-z}, pages = {1344 -- 1355}, year = {2010}, abstract = {Objective: As high-field cardiac MRI (CMR) becomes more widespread the propensity of ECG to interference from electromagnetic fields (EMF) and to magneto-hydrodynamic (MHD) effects increases and with it the motivation for a CMR triggering alternative. This study explores the suitability of acoustic cardiac triggering (ACT) for left ventricular (LV) function assessment in healthy subjects (n=14). Methods: Quantitative analysis of 2D CINE steady-state free precession (SSFP) images was conducted to compare ACT's performance with vector ECG (VCG). Endocardial border sharpness (EBS) was examined paralleled by quantitative LV function assessment. Results: Unlike VCG, ACT provided signal traces free of interference from EMF or MHD effects. In the case of correct Rwave recognition, VCG-triggered 2D CINE SSFP was immune to cardiac motion effects—even at 3.0 T. However, VCG-triggered 2D SSFP CINE imaging was prone to cardiac motion and EBS degradation if R-wave misregistration occurred. ACT-triggered acquisitions yielded LV parameters (end-diastolic volume (EDV), endsystolic volume (ESV), stroke volume (SV), ejection fraction (EF) and left ventricular mass (LVM)) comparable with those derived fromVCG-triggered acquisitions (1.5 T: ESVVCG=(56± 17) ml, EDVVCG=(151±32)ml, LVMVCG=(97±27) g, SVVCG=(94± 19)ml, EFVCG=(63±5)\% cf. ESVACT= (56±18) ml, EDVACT=(147±36) ml, LVMACT=(102±29) g, SVACT=(91± 22) ml, EFACT=(62±6)\%; 3.0 T: ESVVCG=(55±21) ml, EDVVCG=(151±32) ml, LVMVCG=(101±27) g, SVVCG=(96±15) ml, EFVCG=(65±7)\% cf. ESVACT=(54±20) ml, EDVACT=(146±35) ml, LVMACT= (101±30) g, SVACT=(92±17) ml, EFACT=(64±6)\%). Conclusions: ACT's intrinsic insensitivity to interference from electromagnetic fields renders}, language = {en} } @article{RossPlummerRodeetal.2010, author = {Ross, Jillian and Plummer, Simon M. and Rode, Anja and Scheer, Nico and Bower, Conrad C. and Vogel, Ortwin and Henderson, Colin J. and Wolf, C. Roland and Elcombe, Clifford R.}, title = {Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo}, series = {Toxicological Sciences}, volume = {116}, journal = {Toxicological Sciences}, number = {2}, publisher = {Oxford University Press}, address = {Oxford}, issn = {1096-0929}, doi = {10.1093/toxsci/kfq118}, pages = {452 -- 466}, year = {2010}, abstract = {Mouse nongenotoxic hepatocarcinogens phenobarbital (PB) and chlordane induce hepatomegaly characterized by hypertrophy and hyperplasia. Increased cell proliferation is implicated in the mechanism of tumor induction. The relevance of these tumors to human health is unclear. The xenoreceptors, constitutive androstane receptors (CARs), and pregnane X receptor (PXR) play key roles in these processes. Novel "humanized" and knockout models for both receptors were developed to investigate potential species differences in hepatomegaly. The effects of PB (80 mg/kg/4 days) and chlordane (10 mg/kg/4 days) were investigated in double humanized PXR and CAR (huPXR/huCAR), double knockout PXR and CAR (PXRKO/CARKO), and wild-type (WT) C57BL/6J mice. In WT mice, both compounds caused increased liver weight, hepatocellular hypertrophy, and cell proliferation. Both compounds caused alterations to a number of cell cycle genes consistent with induction of cell proliferation in WT mice. However, these gene expression changes did not occur in PXRKO/CARKO or huPXR/huCAR mice. Liver hypertrophy without hyperplasia was demonstrated in the huPXR/huCAR animals in response to both compounds. Induction of the CAR and PXR target genes, Cyp2b10 and Cyp3a11, was observed in both WT and huPXR/huCAR mouse lines following treatment with PB or chlordane. In the PXRKO/CARKO mice, neither liver growth nor induction of Cyp2b10 and Cyp3a11 was seen following PB or chlordane treatment, indicating that these effects are CAR/PXR dependent. These data suggest that the human receptors are able to support the chemically induced hypertrophic responses but not the hyperplastic (cell proliferation) responses. At this time, we cannot be certain that hCAR and hPXR when expressed in the mouse can function exactly as the genes do when they are expressed in human cells. However, all parameters investigated to date suggest that much of their functionality is maintained.}, language = {en} } @article{ScheerRossKapelyukhetal.2010, author = {Scheer, Nico and Ross, Jillian and Kapelyukh, Yury and Rode, Anja and Wolf, C. Roland}, title = {In vivo responses of the human and murine pregnane X receptor to dexamethasone in mice}, series = {Drug Metabolism and Disposition}, volume = {38}, journal = {Drug Metabolism and Disposition}, number = {7}, publisher = {ASPET}, address = {Bethesda}, issn = {1521-009X}, doi = {10.1124/dmd.109.031872}, pages = {1046 -- 1053}, year = {2010}, abstract = {Dexamethasone (DEX) is a potent and widely used anti-inflammatory and immunosuppressant glucocorticoid. It can bind and activate the pregnane X receptor (PXR), which plays a critical role as xenobiotic sensor in mammals to induce the expression of many enzymes, including cytochromes P450 in the CYP3A family. This induction results in its own metabolism. We have used a series of transgenic mouse lines, including a novel, improved humanized PXR line, to compare the induction profile of PXR-regulated drug-metabolizing enzymes after DEX administration, as well as looking at hepatic responses to rifampicin (RIF). The new humanized PXR model has uncovered further intriguing differences between the human and mouse receptors in that RIF only induced Cyp2b10 in the new humanized model. DEX was found to be a much more potent inducer of Cyp3a proteins in wild-type mice than in mice humanized for PXR. To assess whether PXR is involved in the detoxification of DEX in the liver, we analyzed the consequences of high doses of the glucocorticoid on hepatotoxicity on different PXR genetic backgrounds. We also studied these effects in an additional mouse model in which functional mouse Cyp3a genes have been deleted. These strains exhibited different sensitivities to DEX, indicating a protective role of the PXR and CYP3A proteins against the hepatotoxicity of this compound.}, language = {en} } @article{CzarneckiWinkelmannSpiliopoulou2010, author = {Czarnecki, Christian and Winkelmann, Axel and Spiliopoulou, Myra}, title = {Services in electronic telecommunication markets: a framework for planning the virtualization of processes}, series = {Electronic Markets}, volume = {20}, journal = {Electronic Markets}, number = {3-4}, publisher = {Springer}, address = {Berlin}, issn = {1422-8890}, doi = {10.1007/s12525-010-0045-8}, pages = {197 -- 207}, year = {2010}, abstract = {The potential of electronic markets in enabling innovative product bundles through flexible and sustainable partnerships is not yet fully exploited in the telecommunication industry. One reason is that bundling requires seamless de-assembling and re-assembling of business processes, whilst processes in telecommunication companies are often product-dependent and hard to virtualize. We propose a framework for the planning of the virtualization of processes, intended to assist the decision maker in prioritizing the processes to be virtualized: (a) we transfer the virtualization pre-requisites stated by the Process Virtualization Theory in the context of customer-oriented processes in the telecommunication industry and assess their importance in this context, (b) we derive IT-oriented requirements for the removal of virtualization barriers and highlight their demand on changes at different levels of the organization. We present a first evaluation of our approach in a case study and report on lessons learned and further steps to be performed.}, language = {en} } @article{GrajewskiKoesterTurek2010, author = {Grajewski, Matthias and K{\"o}ster, Michael and Turek, Stefam}, title = {Numerical analysis and implementational aspects of a new multilevel grid deformation method}, series = {Applied Numerical Mathematics}, volume = {60}, journal = {Applied Numerical Mathematics}, number = {8}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0168-9274}, doi = {10.1016/j.apnum.2010.03.017}, pages = {767 -- 781}, year = {2010}, abstract = {Recently, we introduced and mathematically analysed a new method for grid deformation (Grajewski et al., 2009) [15] we call basic deformation method (BDM) here. It generalises the method proposed by Liao et al. (Bochev et al., 1996; Cai et al., 2004; Liao and Anderson, 1992) [4], [6], [20]. In this article, we employ the BDM as core of a new multilevel deformation method (MDM) which leads to vast improvements regarding robustness, accuracy and speed. We achieve this by splitting up the deformation process in a sequence of easier subproblems and by exploiting grid hierarchy. Being of optimal asymptotic complexity, we experience speed-ups up to a factor of 15 in our test cases compared to the BDM. This gives our MDM the potential for tackling large grids and time-dependent problems, where possibly the grid must be dynamically deformed once per time step according to the user's needs. Moreover, we elaborate on implementational aspects, in particular efficient grid searching, which is a key ingredient of the BDM.}, language = {en} } @article{Esch2010, author = {Esch, Thomas}, title = {Trends in commercial vehicle powertrains}, series = {ATZautotechnology}, volume = {2010}, journal = {ATZautotechnology}, number = {10}, publisher = {Vieweg \& Sohn}, address = {Wiesbaden}, issn = {2192-886X}, doi = {10.1007/BF03247185}, pages = {26 -- 31}, year = {2010}, abstract = {Low emission zones and truck bans, the rising price of diesel and increases in road tolls: all of these factors are putting serious pressure on the transport industry. Commercial vehicle manufacturers and their suppliers are in the process of identifying new solutions to these challenges as part of their efforts to meet the EEV (enhanced environmentally friendly vehicle) limits, which are currently the most robust European exhaust and emissions standards for trucks and buses.}, language = {en} } @article{Bernecker2010, author = {Bernecker, Andreas}, title = {A European Private Company: Is Europe's single legal form for SMEs close to approval?}, series = {Research Briefing}, journal = {Research Briefing}, publisher = {Deutsche Bank Research}, address = {Frankfurt a. M.}, issn = {2193-5955}, year = {2010}, abstract = {This Research Briefing, issued in July 2010, concluded that: - Small and medium-sized enterprises (SMEs) in Europe have long called for a matching legal form valid across the EU (similar to that of the European company (SE) for large firms) - The main benefits would be the availability of uniform Europe-wide company structures, significant cost reductions for businesses and further integration of the internal market - Given the differing national views regarding the concrete features of the new legal form there is currently no sign of an agreement being reached at the European level in the short term; however, it is possible that progress will be made in negotiations during the year - The key issues being discussed in depth are company formation, transnationality and employee participation rights in the new European private company (SPE).}, language = {en} } @article{AkimbekovZhubanovaMansurovetal.2010, author = {Akimbekov, N. Sh. and Zhubanova, A. A. and Mansurov, Z. A. and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l}, title = {Use of Carbonized Rise Shell for the local treatment of wounds}, series = {Eurasian ChemTech Journal}, volume = {12}, journal = {Eurasian ChemTech Journal}, number = {2}, publisher = {Institute of Combustion Problems}, address = {Almaty}, issn = {2522-4867}, doi = {10.18321/ectj35}, pages = {133 -- 138}, year = {2010}, abstract = {On the model of musculocutaneous wound in rats, the effect of applicative sorption by carbonized rise shell (CRS) on the healing of festering wound was studied. It has been shown, that cytological changes end with rapid scar formation. The use of CRS at the period of severe purulent wound contributes to its favorable course, prevents the development of complications of the animals from sepsis.}, language = {en} } @article{HorstmannBialonskiNoenningetal.2010, author = {Horstmann, Marie-Therese and Bialonski, Stephan and Noenning, Nina and Mai, Heinke and Prusseit, Jens and Wellmer, J{\"o}rg and Hinrichs, Hermann and Lehnertz, Klaus}, title = {State dependent properties of epileptic brain networks: Comparative graph-theoretical analyses of simultaneously recorded EEG and MEG}, series = {Clinical Neurophysiology}, volume = {121}, journal = {Clinical Neurophysiology}, number = {2}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1388-2457}, doi = {10.1016/j.clinph.2009.10.013}, pages = {172 -- 185}, year = {2010}, abstract = {Objective To investigate whether functional brain networks of epilepsy patients treated with antiepileptic medication differ from networks of healthy controls even during the seizure-free interval. Methods We applied different rules to construct binary and weighted networks from EEG and MEG data recorded under a resting-state eyes-open and eyes-closed condition from 21 epilepsy patients and 23 healthy controls. The average shortest path length and the clustering coefficient served as global statistical network characteristics. Results Independent on the behavioral condition, epileptic brains exhibited a more regular functional network structure. Similarly, the eyes-closed condition was characterized by a more regular functional network structure in both groups. The amount of network reorganization due to behavioral state changes was similar in both groups. Consistent findings could be achieved for networks derived from EEG but hardly from MEG recordings, and network construction rules had a rather strong impact on our findings. Conclusions Despite the locality of the investigated processes epileptic brain networks differ in their global characteristics from non-epileptic brain networks. Further methodological developments are necessary to improve the characterization of disturbed and normal functional networks. Significance An increased regularity and a diminished modulation capability appear characteristic of epileptic brain networks.}, language = {en} } @article{BarbazanHagenbachPaulssenetal.2010, author = {Barbaz{\´a}n, Paula and Hagenbach, Adelheid and Paulßen, Elisabeth and Abram, Ulrich and Carballo, Rosa and Rodriguez-Hermida, Sabina and V{\´a}zquez-L{\´o}pez, Ezequiel M.}, title = {Tricarbonyl Rhenium(I) and Technetium(I) Complexes with Hydrazones Derived from 4,5-Diazafluoren-9-one and 1,10-Phenanthroline-5,6-dione}, series = {European Journal of Inorganic Chemistry}, journal = {European Journal of Inorganic Chemistry}, number = {29}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1099-0682}, doi = {10.1002/ejic.201000522}, pages = {4622 -- 4630}, year = {2010}, abstract = {Tricarbonylrhenium(I) and -technetium(I) halide (halide = Cl and Br) complexes of ligands derived from 4,5-diazafluoren-9-one (df) and 1,10-phenanthroline-5,6-dione (phen) derivatives of benzoic and 2-hydroxybenzoic acid hydrazides have been prepared. The complexes have been characterized by elemental analysis, MS, IR, 1H NMR and absorption and emission UV/Vis spectroscopic methods. The metal centres (ReI and TcI) are coordinated through the nitrogen imine atoms and establish five-membered chelate rings, whereas the hydrazone groups stand uncoordinated. The 1H NMR spectra suggest the same behaviour in solution on the basis of only marginal variations in the chemical shifts of the hydrazine protons.}, language = {en} } @article{PaulssenSchweighoeferAbram2010, author = {Paulßen, Elisabeth and Schweigh{\"o}fer, Philip V. and Abram, Ulrich}, title = {Reactions of [ReOX3(PPh3)2] Complexes (X = Cl, Br) with Phenylacetylene and the Structures of the Products}, series = {Zeitschrift f{\"u}r anorganische und allgemeine Chemie : ZAAC = Journal of inorganic and general chemistry}, volume = {636}, journal = {Zeitschrift f{\"u}r anorganische und allgemeine Chemie : ZAAC = Journal of inorganic and general chemistry}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-3749}, doi = {10.1002/zaac.200900478}, pages = {779 -- 783}, year = {2010}, abstract = {Oxorhenium(V) complexes [ReOX3(PPh3)2] (X = Cl, Br) react with phenylacetylene under formation of complexes with ylide-type ligands. Compounds of the compositions [ReOCl3(PPh3){C(Ph)C(H)(PPh3)}] (1), [ReOBr3(OPPh3){C(Ph)C(H)(PPh3)}] (2), and [ReOBr3(OPPh3){C(H)C(Ph)(PPh3)}] (3) were isolated and characterized by X-ray diffraction. They contain a ligand, which was formed by a nucleophilic attack of released PPh3 at coordinated phenylacetylene. The structures of the products show that there is no preferable position for this attack. Cleavage of the Re-C bond in 3 and dimerization of the organic ligand resulted in the formation of the [{(PPh3)(H)CC(Ph)}2]2+ cation, which crystallized as its [(ReOBr4)(OReO3)]2- salt.}, language = {en} } @article{PaulssenAlbertoAbram2010, author = {Paulßen, Elisabeth and Alberto, Roger and Abram, Ulrich}, title = {Synthesis, Characterization, and Structures of R3EOTcO3 Complexes (E = C, Si, Ge, Sn, Pb) and Related Compounds}, series = {Inorganic Chemistry}, volume = {49}, journal = {Inorganic Chemistry}, number = {7}, publisher = {American Chemical Society}, address = {Washington}, issn = {1520-510X}, doi = {10.1021/ic1001094}, pages = {3525 -- 3530}, year = {2010}, abstract = {AgTcO4 reacts with R3ECl compounds (E = C, Si, Ge, Sn, Pb; R = Me, iPr, tBu, Ph), tBu2SnCl2, or PhMgCl under formation of novel trioxotechnetium(VII) derivatives. The carbon and silicon derivatives readily undergo decomposition, which was proven by 99Tc NMR spectroscopy and the isolation of decomposition products such as [TcOCl3(THF)(OH2)]. Compounds [Ph3GeOTcO3], [(THF)Ph3SnOTcO3], [(O3TcO)SntBu2(OH)]2, and [(THF)4Mg(OTcO3)2] are more stable and were isolated in crystalline form and characterized by X-ray diffraction.}, language = {en} } @article{BialonskiHorstmannLehnertz2010, author = {Bialonski, Stephan and Horstmann, Marie-Therese and Lehnertz, Klaus}, title = {From brain to earth and climate systems: Small-world interaction networks or not?}, series = {Chaos: An Interdisciplinary Journal of Nonlinear Science}, volume = {20}, journal = {Chaos: An Interdisciplinary Journal of Nonlinear Science}, number = {1}, publisher = {AIP Publishing}, address = {Melville, NY}, issn = {1089-7682}, doi = {10.1063/1.3360561}, pages = {013134}, year = {2010}, abstract = {We consider recent reports on small-world topologies of interaction networks derived from the dynamics of spatially extended systems that are investigated in diverse scientific fields such as neurosciences, geophysics, or meteorology. With numerical simulations that mimic typical experimental situations, we have identified an important constraint when characterizing such networks: indications of a small-world topology can be expected solely due to the spatial sampling of the system along with the commonly used time series analysis based approaches to network characterization.}, language = {en} } @article{KraffBitzDammannetal.2010, author = {Kraff, Oliver and Bitz, Andreas and Dammann, Philipp and Ladd, Susanne C. and Ladd, Mark E. and Quick, Harald H.}, title = {An eight-channel transmit/receive multipurpose coil for musculoskeletal MR imaging at 7 T}, series = {Medical Physics}, volume = {37}, journal = {Medical Physics}, number = {12}, publisher = {Wiley}, address = {Hoboken, NJ}, issn = {2473-4209}, doi = {10.1118/1.3517176}, pages = {6368 -- 6376}, year = {2010}, abstract = {Purpose: MRI plays a leading diagnostic role in assessing the musculoskeletal (MSK) system and is well established for most questions at clinically used field strengths (up to 3 T). However, there are still limitations in imaging early stages of cartilage degeneration, very fine tendons and ligaments, or in locating nerve lesions, for example. 7 T MRI of the knee has already received increasing attention in the current published literature, but there is a strong need to develop new radiofrequency (RF) coils to assess more regions of the MSK system. In this work, an eight-channel transmit/receive RF array was built as a multipurpose coil for imaging some of the thus far neglected regions. An extensive coil characterization protocol and first in vivo results of the human wrist, shoulder, elbow, knee, and ankle imaged at 7 T will be presented. Methods: Eight surface loop coils with a dimension ofurn:x-wiley:00942405:media:mp7176:mp7176-math-0001 were machined from FR4 circuit board material. To facilitate easy positioning, two coil clusters, each with four loop elements, were combined to one RF transmit/receive array. An overlapped and shifted arrangement of the coil elements was chosen to reduce the mutual inductance between neighboring coils. A phantom made of body-simulating liquid was used for tuning and matching on the bench. Afterward, the S-parameters were verified on a human wrist, elbow, and shoulder. For safety validation, a detailed compliance test was performed including full wave simulations of the RF field distribution and the corresponding specific absorption rate (SAR) for all joints. In vivo images of four volunteers were assessed with gradient echo and spin echo sequences modified to obtain optimal image contrast, full anatomic coverage, and the highest spatial resolution within a reasonable acquisition time. The performance of the RF coil was additionally evaluated by in vivo B1 mapping. Results: A comparison of B1 per unit power, flip angle distribution, and anatomic images showed a fairly homogeneous excitation for the smaller joints (elbow, wrist, and ankle), while for the larger joints, the shoulder and especially the knee, B1 inhomogeneities and limited penetration depth were more pronounced. However, the greater part of the shoulder joint could be imaged.In vivo images rendered very fine anatomic details such as fascicles of the median nerve and the branching of the nerve bundles. High-resolution images of cartilage, labrum, and tendons could be acquired. Additionally, turbo spin echo (TSE) and inversion recovery sequences performed very well. Conclusions: This study demonstrates that the concept of two four-channel transmit/receive RF arrays can be used as a multipurpose coil for high-resolutionin vivo MR imaging of the musculoskeletal system at 7 T. Not only gradient echo but also typical clinical and SAR-intensive sequences such as STIR and TSE performed well. Imaging of small structures and peripheral nerves could in particular benefit from this technique.}, language = {en} } @article{SchlamannYoonMaderwaldetal.2010, author = {Schlamann, Marc and Yoon, Min-Suk and Maderwald, Stefan and Pietrzyk, Thomas and Bitz, Andreas and Gerwig, Marcus and Forsting, Michael and Ladd, Susanne C. and Ladd, Mark E. and Kastrup, Oliver}, title = {Short term effects of magnetic resonance imaging on excitability of the motor cortex at 1.5T and 7T}, series = {Academic Radiology}, volume = {17}, journal = {Academic Radiology}, number = {3}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1076-6332}, doi = {10.1016/j.acra.2009.10.004}, pages = {277 -- 281}, year = {2010}, abstract = {Rationale and Objectives The increasing spread of high-field and ultra-high-field magnetic resonance imaging (MRI) scanners has encouraged new discussion of the safety aspects of MRI. Few studies have been published on possible cognitive effects of MRI examinations. The aim of this study was to examine whether changes are measurable after MRI examinations at 1.5 and 7 T by means of transcranial magnetic stimulation (TMS). Materials and Methods TMS was performed in 12 healthy, right-handed male volunteers. First the individual motor threshold was specified, and then the cortical silent period (SP) was measured. Subsequently, the volunteers were exposed to the 1.5-T MRI scanner for 63 minutes using standard sequences. The MRI examination was immediately followed by another TMS session. Fifteen minutes later, TMS was repeated. Four weeks later, the complete setting was repeated using a 7-T scanner. Control conditions included lying in the 1.5-T scanner for 63 minutes without scanning and lying in a separate room for 63 minutes. TMS was performed in the same way in each case. For statistical analysis, Wilcoxon's rank test was performed. Results Immediately after MRI exposure, the SP was highly significantly prolonged in all 12 subjects at 1.5 and 7 T. The motor threshold was significantly increased. Fifteen minutes after the examination, the measured value tended toward normal again. Control conditions revealed no significant differences. Conclusion MRI examinations lead to a transient and highly significant alteration in cortical excitability. This effect does not seem to depend on the strength of the static magnetic field.}, language = {en} } @article{SchlamannVoigtMaderwaldetal.2010, author = {Schlamann, Marc and Voigt, Melanie A. and Maderwald, Stefan and Bitz, Andreas and Kraff, Oliver and Ladd, Susanne C. and Ladd, Mark E. and Forsting, Michael and Wilhelm, Hans}, title = {Exposure to high-field MRI does not affect cognitive function}, series = {Journal of Magnetic Resonance Imaging}, volume = {31}, journal = {Journal of Magnetic Resonance Imaging}, number = {5}, publisher = {Wiley-Liss}, address = {New York}, issn = {1522-2586}, doi = {10.1002/jmri.22065}, pages = {1061 -- 1066}, year = {2010}, abstract = {Purpose To assess potential cognitive deficits under the influence of static magnetic fields at various field strengths some studies already exist. These studies were not focused on attention as the most vulnerable cognitive function. Additionally, mostly no magnetic resonance imaging (MRI) sequences were performed. Materials and Methods In all, 25 right-handed men were enrolled in this study. All subjects underwent one MRI examination of 63 minutes at 1.5 T and one at 7 T within an interval of 10 to 30 days. The order of the examinations was randomized. Subjects were referred to six standardized neuropsychological tests strictly focused on attention immediately before and after each MRI examination. Differences in neuropsychological variables between the timepoints before and after each MRI examination were assessed and P-values were calculated Results Only six subtests revealed significant differences between pre- and post-MRI. In these tests the subjects achieved better results in post-MRI testing than in pre-MRI testing (P = 0.013-0.032). The other tests revealed no significant results. Conclusion The improvement in post-MRI testing is only explicable as a result of learning effects. MRI examinations, even in ultrahigh-field scanners, do not seem to have any persisting influence on the attention networks of human cognition immediately after exposure.}, language = {en} } @article{TippkoetterRoikaewUlberetal.2010, author = {Tippk{\"o}tter, Nils and Roikaew, Wipa and Ulber, Roland and Hoffmann, Alexander and Denzler, Hans-J{\"o}rg and Buchholz, Heinrich}, title = {Paracoccus denitrificans for the effluent recycling during continuous denitrification of liquid food}, series = {Biotechnology Progress}, volume = {26}, journal = {Biotechnology Progress}, number = {3}, publisher = {Wiley}, address = {Hoboken, NJ}, issn = {8756-7938}, doi = {10.1002/btpr.384}, pages = {756 -- 762}, year = {2010}, abstract = {Nitrate is an undesirable component of several foods. A typical case of contamination with high nitrate contents is whey concentrate, containing nitrate in concentrations up to 25 l. The microbiological removal of nitrate by Paracoccus denitrificans under formation of harmless nitrogen in combination with a cell retention reactor is described here. Focus lies on the resource-conserving design of a microbal denitrification process. Two methods are compared. The application of polyvinyl alcohol-immobilized cells, which can be applied several times in whey feed, is compared with the implementation of a two step denitrification system. First, the whey concentrate's nitrate is removed by ion exchange and subsequently the eluent regenerated by microorganisms under their retention by crossflow filtration. Nitrite and nitrate concentrations were determined by reflectometric color measurement with a commercially available Reflectoquant® device. Correction factors for these media had to be determined. During the pilot development, bioreactors from 4 to 250 mg·L-1 and crossflow units with membrane areas from 0.02 to 0.80 m2 were examined. Based on the results of the pilot plants, a scaling for the exemplary process of denitrifying 1,000 tons per day is discussed.}, language = {en} } @article{OrzadaMaderwaldPoseretal.2010, author = {Orzada, Stephan and Maderwald, Stefan and Poser, Benedikt Andreas and Bitz, Andreas and Quick, Harald H. and Ladd, Mark E.}, title = {RF excitation using time interleaved acquisition of modes (TIAMO) to address B1 inhomogeneity in high-field MRI}, series = {Magnetic Resonance in Medicine}, volume = {64}, journal = {Magnetic Resonance in Medicine}, number = {2}, publisher = {Wiley-Liss}, address = {New York}, issn = {1522-2594}, doi = {10.1002/mrm.22527}, pages = {327 -- 333}, year = {2010}, abstract = {As the field strength and, therefore, the operational frequency in MRI is increased, the wavelength approaches the size of the human head/body, resulting in wave effects, which cause signal decreases and dropouts. Several multichannel approaches have been proposed to try to tackle these problems, including RF shimming, where each element in an array is driven by its own amplifier and modulated with a certain (constant) amplitude and phase relative to the other elements, and Transmit SENSE, where spatially tailored RF pulses are used. In this article, a relatively inexpensive and easy to use imaging scheme for 7 Tesla imaging is proposed to mitigate signal voids due to B1 field inhomogeneity. Two time-interleaved images are acquired using a different excitation mode for each. By forming virtual receive elements, both images are reconstructed together using GRAPPA to achieve a more homogeneous image, with only small SNR and SAR penalty in head and body imaging at 7 Tesla.}, language = {en} } @article{AggeloussisGiannakouAlbrachtetal.2010, author = {Aggeloussis, Nickos and Giannakou, Erasmia and Albracht, Kirsten and Arampatzis, Adamantios}, title = {Reproducibility of fascicle length and pennation angle of gastrocnemius medialis in human gait in vivo}, series = {Gait and Posture}, volume = {31}, journal = {Gait and Posture}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0966-6362}, doi = {10.1016/j.gaitpost.2009.08.249}, pages = {73 -- 77}, year = {2010}, abstract = {The purpose of the current study was to examine the reproducibility of fascicle length and pennation angle of gastrocnemius medialis while human walking. To the best of our knowledge, this is the first study of the reproducibility of fascicle length and pennation angle of gastrocnemius medialis in vivo during human gait. Twelve males performed 10 gait trials on a treadmill, in 2 separate days. B-mode ultrasonography, with the ultrasound probe firmly adjusted in the transverse and frontal planes using a special cast, was used to measure the fascicle length and the pennation angle of the gastrocnemius medialis (GM). A Vicon 624 system with three cameras operating at 120 Hz was also used to record the ankle and knee joint angles. The results showed that measurements of fascicle length and pennation angle showed high reproducibility during the gait cycle, both within the same day and between different days. Moreover, the root mean square differences between the repeated waveforms of both variables were very small, compared with their ranges (fascicle length: RMS = ∼3 mm, range: 38-63 mm; pennation angle: RMS = ∼1.5°, range: 22-32°). However, their reproducibility was lower compared to the joint angles. It was found that representative data have to be derived by a wide number of gait trials (fascicle length ∼six trials, pennation angle more than 10 trials), to assure the reliability of the fascicle length and pennation angle in human gait.}, language = {en} } @article{ArampatzisPeperBierbaumetal.2010, author = {Arampatzis, Adamantios and Peper, Andreas and Bierbaum, Stefanie and Albracht, Kirsten}, title = {Plasticity of human Achilles tendon mechanical and morphological properties in response to cyclic strain}, series = {Journal of Biomechanics}, volume = {43}, journal = {Journal of Biomechanics}, number = {16}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0021-9290}, doi = {10.1016/j.jbiomech.2010.08.014}, pages = {3073 -- 3079}, year = {2010}, abstract = {The purpose of the current study in combination with our previous published data (Arampatzis et al., 2007) was to examine the effects of a controlled modulation of strain magnitude and strain frequency applied to the Achilles tendon on the plasticity of tendon mechanical and morphological properties. Eleven male adults (23.9±2.2 yr) participated in the study. The participants exercised one leg at low magnitude tendon strain (2.97±0.47\%), and the other leg at high tendon strain magnitude (4.72±1.08\%) of similar frequency (0.5 Hz, 1 s loading, 1 s relaxation) and exercise volume (integral of the plantar flexion moment over time) for 14 weeks, 4 days per week, 5 sets per session. The exercise volume was similar to the intervention of our earlier study (0.17 Hz frequency; 3 s loading, 3 s relaxation) allowing a direct comparison of the results. Before and after the intervention ankle joint moment has been measured by a dynamometer, tendon-aponeurosis elongation by ultrasound and cross-sectional area of the Achilles tendon by magnet resonance images (MRI). We found a decrease in strain at a given tendon force, an increase in tendon-aponeurosis stiffness and tendon elastic modulus of the Achilles tendon only in the leg exercised at high strain magnitude. The cross-sectional area (CSA) of the Achilles tendon did not show any statistically significant (P>0.05) differences to the pre-exercise values in both legs. The results indicate a superior improvement in tendon properties (stiffness, elastic modulus and CSA) at the low frequency (0.17 Hz) compared to the high strain frequency (0.5 Hz) protocol. These findings provide evidence that the strain magnitude applied to the Achilles tendon should exceed the value, which occurs during habitual activities to trigger adaptational effects and that higher tendon strain duration per contraction leads to superior tendon adaptational responses.}, language = {en} } @article{VogtMottaghyWolfetal.2010, author = {Vogt, C. and Mottaghy, Darius and Wolf, A. and Rath, V. and Pechnig, R. and Clauser, C.}, title = {Reducing temperature uncertainties by stochastic geothermal reservoir modelling}, series = {Geophysical Journal International}, volume = {181}, journal = {Geophysical Journal International}, number = {1}, publisher = {Oxford University Press}, address = {Oxford}, issn = {1365-246X}, doi = {10.1111/j.1365-246X.2009.04498.x}, pages = {321 -- 333}, year = {2010}, abstract = {Quantifying and minimizing uncertainty is vital for simulating technically and economically successful geothermal reservoirs. To this end, we apply a stochastic modelling sequence, a Monte Carlo study, based on (i) creating an ensemble of possible realizations of a reservoir model, (ii) forward simulation of fluid flow and heat transport, and (iii) constraining post-processing using observed state variables. To generate the ensemble, we use the stochastic algorithm of Sequential Gaussian Simulation and test its potential fitting rock properties, such as thermal conductivity and permeability, of a synthetic reference model and—performing a corresponding forward simulation—state variables such as temperature. The ensemble yields probability distributions of rock properties and state variables at any location inside the reservoir. In addition, we perform a constraining post-processing in order to minimize the uncertainty of the obtained distributions by conditioning the ensemble to observed state variables, in this case temperature. This constraining post-processing works particularly well on systems dominated by fluid flow. The stochastic modelling sequence is applied to a large, steady-state 3-D heat flow model of a reservoir in The Hague, Netherlands. The spatial thermal conductivity distribution is simulated stochastically based on available logging data. Errors of bottom-hole temperatures provide thresholds for the constraining technique performed afterwards. This reduce the temperature uncertainty for the proposed target location significantly from 25 to 12 K (full distribution width) in a depth of 2300 m. Assuming a Gaussian shape of the temperature distribution, the standard deviation is 1.8 K. To allow a more comprehensive approach to quantify uncertainty, we also implement the stochastic simulation of boundary conditions and demonstrate this for the basal specific heat flow in the reservoir of The Hague. As expected, this results in a larger distribution width and hence, a larger, but more realistic uncertainty estimate. However, applying the constraining post-processing the uncertainty is again reduced to the level of the post-processing without stochastic boundary simulation. Thus, constraining post-processing is a suitable tool for reducing uncertainty estimates by observed state variables.}, language = {en} } @article{Kirsch2010, author = {Kirsch, Ansgar}, title = {Experimental investigation of the face stability of shallow tunnels in sand}, series = {Acta Geotechnica}, volume = {5}, journal = {Acta Geotechnica}, number = {1}, publisher = {Springer}, address = {Berlin}, issn = {1861-1125}, doi = {10.1007/s11440-010-0110-7}, pages = {43 -- 62}, year = {2010}, abstract = {Various models have been proposed for the prediction of the necessary support pressure at the face of a shallow tunnel. To assess their quality, the collapse of a tunnel face was modelled with small-scale model tests at single gravity. The development of the failure mechanism and the support force at the face in dry sand were investigated. The observed displacement patterns show a negligible influence of overburden on the extent and evolution of the failure zone. The latter is significantly influenced, though, by the initial density of the sand: in dense sand a chimney-wedge-type collapse mechanism developed, which propagated towards the soil surface. Initially, loose sand did not show any discrete collapse mechanism. The necessary support force was neither influenced by the overburden nor the initial density. A comparison with quantitative predictions by several theoretical models showed that the measured necessary support pressure is overestimated by most of the models. Those by Vermeer/Ruse and L{\´e}ca/Dormieux showed the best agreement to the measurements.}, language = {en} } @article{FellinKingKirschetal.2010, author = {Fellin, Wolfgang and King, Julian and Kirsch, Ansgar and Oberguggenberger, Michael}, title = {Uncertainty modelling and sensitivity analysis of tunnel face stability}, series = {Structural safety}, volume = {32}, journal = {Structural safety}, number = {6}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0167-4730}, doi = {10.1016/j.strusafe.2010.06.001}, pages = {402 -- 410}, year = {2010}, abstract = {This paper proposes an approach to the choice and evaluation of engineering models with the aid of a typical application in geotechnics. An important issue in the construction of shallow tunnels, especially in weak ground conditions, is the tunnel face stability. Various theoretical and numerical models for predicting the necessary support pressure have been put forth in the literature. In this paper, we combine laboratory experiments performed at the University of Innsbruck with current methods of uncertainty and sensitivity analysis for assessing adequacy, predictive power and robustness of the models. The major issues are the handling of the twofold uncertainty of test results and of model predictions as well as the decision about what are the influential input parameters.}, language = {en} } @article{FleischhakerEversDey2010, author = {Fleischhaker, Robert and Evers, J{\"o}rg and Dey, Tarak N.}, title = {Phase modulation induced by cooperative effects in electromagnetically induced transparency}, series = {Physical Review A - Atomic, molecular, and optical physics}, volume = {82}, journal = {Physical Review A - Atomic, molecular, and optical physics}, number = {1}, publisher = {AIP Publishing}, address = {Melville, NY}, issn = {1050-2947}, doi = {10.1103/PhysRevA.82.013815}, pages = {013815}, year = {2010}, abstract = {We analyze the influence of dipole-dipole interactions in an electromagnetically induced transparency set up for a density at the onset of cooperative effects. To this end, we include mean-field models for the influence of local-field corrections and radiation trapping into our calculation. We show both analytically and numerically that the polarization contribution to the local field strongly modulates the phase of a weak pulse. We give an intuitive explanation for this local-field-induced phase modulation and demonstrate that it distinctively differs from the nonlinear self-phase-modulation that a strong pulse experiences in a Kerr medium.}, language = {en} } @article{FontivonArxGarciaGonzalezetal.2010, author = {Fonti, Patrick and von Arx, Georg and Garc{\´i}a-Gonz{\´a}lez, Ignacio and Eilmann, Britta and Sass-Klaassen, Ute G. W. and G{\"a}rtner, Holger and Eckstein, Dieter}, title = {Studying global change through investigation of the plastic responses of xylem anatomy in tree rings}, series = {New Phytologist}, volume = {185}, journal = {New Phytologist}, number = {1}, publisher = {Wiley-Blackwell}, address = {Oxford}, issn = {1469-8137 (Online)}, doi = {10.1111/j.1469-8137.2009.03030.x}, pages = {42 -- 53}, year = {2010}, abstract = {Variability in xylem anatomy is of interest to plant scientists because of the role water transport plays in plant performance and survival. Insights into plant adjustments to changing environmental conditions have mainly been obtained through structural and functional comparative studies between taxa or within taxa on contrasting sites or along environmental gradients. Yet, a gap exists regarding the study of hydraulic adjustments in response to environmental changes over the lifetimes of plants. In trees, dated tree-ring series are often exploited to reconstruct dynamics in ecological conditions, and recent work in which wood-anatomical variables have been used in dendrochronology has produced promising results. Environmental signals identified in water-conducting cells carry novel information reflecting changes in regional conditions and are mostly related to short, sub-annual intervals. Although the idea of investigating environmental signals through wood anatomical time series goes back to the 1960s, it is only recently that low-cost computerized image-analysis systems have enabled increased scientific output in this field. We believe that the study of tree-ring anatomy is emerging as a promising approach in tree biology and climate change research, particularly if complemented by physiological and ecological studies. This contribution presents the rationale, the potential, and the methodological challenges of this innovative approach.}, language = {en} } @article{DobbertinEilmannBleuleretal.2010, author = {Dobbertin, Matthias and Eilmann, Britta and Bleuler, Peter and Giuggiola, Arnaud and Graf Pannatier, Elisabeth and Landolt, Werner and Schleppi, Patrick and Rigling, Andreas}, title = {Effect of irrigation on needle morphology, shoot and stem growth in a drought-exposed Pinus sylvestris forest}, series = {Tree Physiology}, volume = {30}, journal = {Tree Physiology}, number = {3}, publisher = {Oxford University Press}, address = {Oxford}, issn = {1758-4469 (Online)}, doi = {10.1093/treephys/tpp123}, pages = {346 -- 360}, year = {2010}, abstract = {In Valais, Switzerland, Scots pines (Pinus sylvestris L.) are declining, mainly following drought. To assess the impact of drought on tree growth and survival, an irrigation experiment was initiated in 2003 in a mature pine forest, approximately doubling the annual precipitation. Tree crown transparency (lack of foliage) and leaf area index (LAI) were annually assessed. Seven irrigated and six control trees were felled in 2006, and needles, stem discs and branches were taken for growth analysis. Irrigation in 2004 and 2005, both with below-average precipitation, increased needle size, area and mass, stem growth and, with a 1-year delay, shoot length. This led to a relative decrease in tree crown transparency (-14\%) and to an increase in stand LAI (+20\%). Irrigation increased needle length by 70\%, shoot length by 100\% and ring width by 120\%, regardless of crown transparency. Crown transparency correlated positively with mean needle size, shoot length and ring width and negatively with specific leaf area. Trees with high crown transparency (low growth, short needles) experienced similar increases in needle mass and growth with irrigation than trees with low transparency (high growth, long needles), indicating that seemingly declining trees were able to 'recover' when water supply became sufficient. A simple drought index before and during the irrigation explained most of the variation found in the parameters for both irrigated and control trees.}, language = {en} } @article{EilmannBuchmannSiegwolfetal.2010, author = {Eilmann, Britta and Buchmann, Nina and Siegwolf, Rolf and Saurer, Matthias and Cherubini, Paolo and Rigling, Andreas}, title = {Fast response of Scots pine to improved water availability reflected in tree-ring width and δ13C}, series = {Plant, Cell and Environment}, volume = {33}, journal = {Plant, Cell and Environment}, number = {8}, publisher = {Wiley-Blackwell}, address = {Oxford}, issn = {1365-3040 (Online)}, doi = {10.1111/j.1365-3040.2010.02153.x}, pages = {1351 -- 1360}, year = {2010}, abstract = {Drought-induced forest decline, like the Scots pine mortality in inner-Alpine valleys, will gain in importance as the frequency and severity of drought events are expected to increase. To understand how chronic drought affects tree growth and tree-ring δ13C values, we studied mature Scots pine in an irrigation experiment in an inner-Alpine valley. Tree growth and isotope analyses were carried out at the annual and seasonal scale. At the seasonal scale, maximum δ13C values were measured after the hottest and driest period of the year, and were associated with decreasing growth rates. Inter-annual δ13C values in early- and latewood showed a strong correlation with annual climatic conditions and an immediate decrease as a response to irrigation. This indicates a tight coupling between wood formation and the freshly produced assimilates for trees exposed to chronic drought. This rapid appearance of the isotopic signal is a strong indication for an immediate and direct transfer of newly synthesized assimilates for biomass production. The fast appearance and the distinct isotopic signal suggest a low availability of old stored carbohydrates. If this was a sign for C-storage depletion, an increasing mortality could be expected when stressors increase the need for carbohydrate for defence, repair or regeneration.}, language = {en} } @article{EgliAyerPeteretal.2010, author = {Egli, Simon and Ayer, Fran{\c{c}}ois and Peter, Martina and Eilmann, Britta and Rigling, Andreas}, title = {Is forest mushroom productivity driven by tree growth? Results from a thinning experiment}, series = {Annals of Forest Science}, volume = {67}, journal = {Annals of Forest Science}, number = {5}, publisher = {Springer}, address = {Paris}, issn = {1286-4560 (Print)}, doi = {10.1051/forest/2010011}, pages = {509}, year = {2010}, abstract = {• Most of the edible forest mushrooms are mycorrhizal and depend on carbohydrates produced by the associated trees. Fruiting patterns of these fungi are not yet fully understood since climatic factors alone do not completely explain mushroom occurrence. • The objective of this study was to retrospectively find out if changing tree growth following an increment thinning has influenced the diversity patterns and productivity of associated forest mushrooms in the fungus reserve La Chan{\´e}az, Switzerland. • The results reveal a clear temporal relationship between the thinning, the growth reaction of trees and the reaction of the fungal community, especially for the ectomycorrhizal species. The tree-ring width of the formerly suppressed beech trees and the fruit body number increased after thinning, leading to a significantly positive correlation between fruit body numbers and tree-ring width. • Fruit body production was influenced by previous annual tree growth, the best accordance was found between fruit body production and the tree-ring width two years previously. • The results support the hypothesis that ectomycorrhizal fruit body production must be linked with the growth of the associated host trees. Moreover, the findings indicate the importance of including mycorrhizal fungi as important players when discussing a tree as a carbon source or sink.}, language = {en} } @article{RiglingEilmannKoechlietal.2010, author = {Rigling, Andreas and Eilmann, Britta and Koechli, Roger and Dobbertin, Matthias}, title = {Mistletoe-induced crown degradation in Scots pine in a xeric environment}, volume = {30}, number = {7}, publisher = {Oxford University Press}, address = {Oxford}, issn = {1758-4469 (Online)}, doi = {10.1093/treephys/tpq038}, pages = {845 -- 832}, year = {2010}, abstract = {Increasing Scots pine (Pinus sylvestris L.) mortality has been recently observed in the dry inner valleys of the European Alps. Besides drought, infection with pine mistletoe (Viscum album ssp. austriacum) seems to play an important role in the mortality dynamics of Scots pines, but how mistletoes promote pine decline remains unclear. To verify whether pine mistletoe infection weakens the host via crown degradation, as observed for dwarf mistletoes, we studied the negative effects of pine mistletoe infestation on the photosynthetic tissues and branch growth of pairs of infested and non-infested branches. Pine mistletoe infection leads to crown degradation in its host by reducing the length, the radial increment, the ramification, the needle length and the number of needle years of the infested branches. This massive loss in photosynthetic tissue results in a reduction in primary production and a subsequent decrease in carbohydrate availability. The significant reduction in needle length due to mistletoe infection is an indication for a lower water and nutrient availability in infested branches. Thus, mistletoe infection might lead to a decrease in the availability of water and carbohydrates, the two most important growth factors, which are already shortened due to the chronic drought situation in the area. Therefore, pine mistletoe increases the risk of drought-induced mortality of its host when growing in a xeric environment.}, language = {en} } @article{BragardSoltauThomasetal.2010, author = {Bragard, Michael and Soltau, N. and Thomas, S. and De Doncker, R. W.}, title = {The balance of renewable sources and user demands in grids : power electronics for modular battery energy storage systems}, series = {IEEE transactions on power electronics}, volume = {25}, journal = {IEEE transactions on power electronics}, number = {12}, publisher = {IEEE}, address = {New York}, issn = {0885-8993}, doi = {10.1109/TPEL.2010.2085455}, pages = {3049 -- 3056}, year = {2010}, abstract = {The continuously growing amount of renewable sources starts compromising the stability of electrical grids. Contradictory to fossil fuel power plants, energy production of wind and photovoltaic (PV) energy is fluctuating. Although predictions have significantly improved, an outage of multi-MW offshore wind farms poses a challenging problem. One solution could be the integration of storage systems in the grid. After a short overview, this paper focuses on two exemplary battery storage systems, including the required power electronics. The grid integration, as well as the optimal usage of volatile energy reserves, is presented for a 5- kW PV system for home application, as well as for a 100- MW medium-voltage system, intended for wind farm usage. The efficiency and cost of topologies are investigated as a key parameter for large-scale integration of renewable power at medium- and low-voltage.}, language = {en} } @article{DegeringEggertPulsetal.2010, author = {Degering, Christian and Eggert, Thorsten and Puls, Michael and Bongaerts, Johannes and Evers, Stefan and Maurer, Karl-Heinz and Jaeger, Karl-Erich}, title = {Optimization of protease secretion in Bacillus subtilis and Bacillus licheniformis by screening of homologous and herologous signal peptides}, series = {Applied and environmental microbiology}, volume = {76}, journal = {Applied and environmental microbiology}, number = {19}, publisher = {American Society for Microbiology}, address = {Washington, DC}, issn = {1098-5336 (E-Journal); 0003-6919 (Print); 0099-2240 (Print)}, doi = {10.1128/AEM.01146-10}, pages = {6370 -- 6378}, year = {2010}, abstract = {Bacillus subtilis and Bacillus licheniformis are widely used for the large-scale industrial production of proteins. These strains can efficiently secrete proteins into the culture medium using the general secretion (Sec) pathway. A characteristic feature of all secreted proteins is their N-terminal signal peptides, which are recognized by the secretion machinery. Here, we have studied the production of an industrially important secreted protease, namely, subtilisin BPN′ from Bacillus amyloliquefaciens. One hundred seventy-three signal peptides originating from B. subtilis and 220 signal peptides from the B. licheniformis type strain were fused to this secretion target and expressed in B. subtilis, and the resulting library was analyzed by high-throughput screening for extracellular proteolytic activity. We have identified a number of signal peptides originating from both organisms which produced significantly increased yield of the secreted protease. Interestingly, we observed that levels of extracellular protease were improved not only in B. subtilis, which was used as the screening host, but also in two different B. licheniformis strains. To date, it is impossible to predict which signal peptide will result in better secretion and thus an improved yield of a given extracellular target protein. Our data show that screening a library consisting of homologous and heterologous signal peptides fused to a target protein can identify more-effective signal peptides, resulting in improved protein export not only in the original screening host but also in different production strains.}, language = {en} } @article{ReisgenSchleserMokrovetal.2010, author = {Reisgen, Uwe and Schleser, Markus and Mokrov, Oleg and Ahmed, Essam}, title = {Uni- and bi-axial deformation behavior of laser welded advanced high strength steel sheets}, series = {Journal of materials processing technology}, volume = {210}, journal = {Journal of materials processing technology}, number = {15}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0924-0136}, doi = {http10.1016/j.jmatprotec.2010.08.003}, pages = {2188 -- 2196}, year = {2010}, abstract = {Bead-on-plate butt joints of 2.5 mm hot rolled DP600/DP600 and 1.2 mm cold rolled TRIP700/TRIP700 steel sheets were performed using 6 kW CO2 laser beam welding. The welding speed ranged from 1.5 to 3.0 and from 2.1 to 3.9 m/min in DP/DP and TRIP/TRIP steel weldments respectively. A top surface helium gas was used as a shielding gas at a flow rate of 20 l/min. Metallographic examinations and transverse tensile testing (DIN EN 895: 1995) were carried out to characterize the weldments. The formability of base metals and weldments were investigated by standard Erichsen test (DIN EN ISO 20482). It was found that the uniaxial plastic behavior of both DP600 and TRIP700 base metals was in agreement with Swift and modified Mecking-Kocks models respectively. In a perpendicular tensile test to the weld line, all specimens were fractured at the base metal however the strengths were somewhat higher than those of base metal. There was a significant reduction in formability caused by welding of both DP/DP and TRIP/TRIP steel weldments and the formability has been improved with the increase of the welding speed.}, language = {en} }