@article{WincklerKruegerSchnitzleretal.2014, author = {Winckler, Silvia and Krueger, Rolf and Schnitzler, Thomas and Zang, Werner and Fischer, Rainer and Biselli, Manfred}, title = {A sensitive monitoring system for mammalian cell cultivation processes: a PAT approach}, series = {Bioprocess and biosystems engineering}, volume = {37}, journal = {Bioprocess and biosystems engineering}, number = {5}, publisher = {Springer}, address = {Berlin, Heidelberg}, issn = {1615-7591 (Print) 1615-7605 (Online)}, doi = {10.1007/s00449-013-1062-8}, pages = {901 -- 912}, year = {2014}, abstract = {Biopharmaceuticals such as antibodies are produced in cultivated mammalian cells, which must be monitored to comply with good manufacturing practice. We, therefore, developed a fully automated system comprising a specific exhaust gas analyzer, inline analytics and a corresponding algorithm to precisely determine the oxygen uptake rate, carbon dioxide evolution rate, carbon dioxide transfer rate, transfer quotient and respiratory quotient without interrupting the ongoing cultivation, in order to assess its reproducibility. The system was verified using chemical simulation experiments and was able to measure the respiratory activity of hybridoma cells and DG44 cells (derived from Chinese hamster ovary cells) with satisfactory results at a minimum viable cell density of ~2.0 × 10⁵ cells ml⁻¹. The system was suitable for both batch and fed-batch cultivations in bubble-aerated and membrane-aerated reactors, with and without the control of pH and dissolved oxygen.}, language = {en} } @article{BoehnischBraunMuscarelloetal.2023, author = {B{\"o}hnisch, Nils and Braun, Carsten and Muscarello, Vincenzo and Marzocca, Pier}, title = {A sensitivity study on aeroelastic instabilities of slender wings with a large propeller}, series = {AIAA SCITECH 2023 Forum}, journal = {AIAA SCITECH 2023 Forum}, publisher = {AIAA}, doi = {10.2514/6.2023-1893}, pages = {1 -- 14}, year = {2023}, abstract = {Next-generation aircraft designs often incorporate multiple large propellers attached along the wingspan. These highly flexible dynamic systems can exhibit uncommon aeroelastic instabilities, which should be carefully investigated to ensure safe operation. The interaction between the propeller and the wing is of particular importance. It is known that whirl flutter is stabilized by wing motion and wing aerodynamics. This paper investigates the effect of a propeller onto wing flutter as a function of span position and mounting stiffness between the propeller and wing. The analysis of a comparison between a tractor and pusher configuration has shown that the coupled system is more stable than the standalone wing for propeller positions near the wing tip for both configurations. The wing fluttermechanism is mostly affected by the mass of the propeller and the resulting change in eigenfrequencies of the wing. For very weak mounting stiffnesses, whirl flutter occurs, which was shown to be stabilized compared to a standalone propeller due to wing motion. On the other hand, the pusher configuration is, as to be expected, the more critical configuration due to the attached mass behind the elastic axis.}, language = {de} } @article{HarzheimMuehmelHeuermann2021, author = {Harzheim, Thomas and M{\"u}hmel, Marc and Heuermann, Holger}, title = {A SFCW harmonic radar system for maritime search and rescue using passive and active tags}, series = {International Journal of Microwave and Wireless Technologies}, volume = {13}, journal = {International Journal of Microwave and Wireless Technologies}, number = {Special Issue 7}, publisher = {Cambridge University Press}, address = {Cambridge}, doi = {10.1017/S1759078721000520}, pages = {691 -- 707}, year = {2021}, abstract = {This paper introduces a new maritime search and rescue system based on S-band illumination harmonic radar (HR). Passive and active tags have been developed and tested while attached to life jackets and a small boat. In this demonstration test carried out on the Baltic Sea, the system was able to detect and range the active tags up to a distance of 5800 m using an illumination signal transmit-power of 100 W. Special attention is given to the development, performance, and conceptual differences between passive and active tags used in the system. Guidelines for achieving a high HR dynamic range, including a system components description, are given and a comparison with other HR systems is performed. System integration with a commercial maritime X-band navigation radar is shown to demonstrate a solution for rapid search and rescue response and quick localization.}, language = {en} } @article{SchoeningBussFassbenderetal.2000, author = {Sch{\"o}ning, Michael Josef and Buß, G. and Faßbender, F. and Gl{\"u}ck, O. and Schmitt, G. and Schultze, J. W. and L{\"u}th, H.}, title = {A silicon-based microelectrode array for chemical analysis}, series = {Sensors and Actuators B. 65 (2000), H. 1-3}, journal = {Sensors and Actuators B. 65 (2000), H. 1-3}, isbn = {0925-4005}, pages = {284 -- 287}, year = {2000}, language = {en} } @article{SchoeningBussFassbenderetal.1998, author = {Sch{\"o}ning, Michael Josef and Buß, G. and Faßbender, F. and Gl{\"u}ck, O. and Schmitt, G. and Schultze, J. W. and L{\"u}th, H.}, title = {A silicon-based microelectrode array for chemical analysis}, series = {Proceedings of the Seventh International Meeting on Chemical Sensors : 27 - 30 July, 1998, Beijing, P. R. China / ed. Zhi-Gang Zhou}, journal = {Proceedings of the Seventh International Meeting on Chemical Sensors : 27 - 30 July, 1998, Beijing, P. R. China / ed. Zhi-Gang Zhou}, publisher = {Elsevier}, address = {Amsterdam [u.a.]}, pages = {100 -- 102}, year = {1998}, language = {en} } @article{BaeckerPouyeshmanSchnitzleretal.2011, author = {B{\"a}cker, Matthias and Pouyeshman, S. and Schnitzler, Thomas and Poghossian, Arshak and Wagner, Patrick and Biselli, Manfred and Sch{\"o}ning, Michael Josef}, title = {A silicon-based multi-sensor chip for monitoring of fermentation processes}, series = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6}, journal = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6}, publisher = {Wiley}, address = {Weinheim}, isbn = {1862-6319}, pages = {1364 -- 1369}, year = {2011}, language = {en} } @article{SchoeningWeidenbrueckThustetal.1997, author = {Sch{\"o}ning, Michael Josef and Weidenbr{\"u}ck, B. and Thust, M. and Kordos, P. and L{\"u}th, H.}, title = {A silicon-based sensor array with capacitive EIS structures}, series = {Proceedings of the 11th European Conference on Solid-State Transducers / Eurosensors XI, September 21 - 24, 1997, Warsaw, Poland. [Organised by] Warsaw University of Technology. Vol 2.}, journal = {Proceedings of the 11th European Conference on Solid-State Transducers / Eurosensors XI, September 21 - 24, 1997, Warsaw, Poland. [Organised by] Warsaw University of Technology. Vol 2.}, publisher = {Sensor Lab Sp.}, address = {Warsaw}, isbn = {83-908335-0-6}, pages = {871 -- 874}, year = {1997}, language = {en} } @article{PieperKlein2011, author = {Pieper, Martin and Klein, Peter}, title = {A simple and accurate numerical network flow model for bionic micro heat exchangers}, series = {Heat mass transfer}, volume = {47}, journal = {Heat mass transfer}, number = {5}, publisher = {Springer}, address = {Berlin}, isbn = {0947-7411}, pages = {491 -- 503}, year = {2011}, language = {en} } @article{PrumeBooijVogletal.2007, author = {Prume, Klaus and Booij, W. E. and Vogl, A. H. and Wang, D. T.}, title = {A simple and powerful analytical model for MEMS piezoelectric multimorphs / Booij, W. E. ; Vogl, A. H. ; Wang, D. T. ; Tyholdt, F. ; Ostbo, N. P. ; Raeder, H. ; Prume, K.}, series = {Journal of Electroceramics. 19 (2007), H. 4}, journal = {Journal of Electroceramics. 19 (2007), H. 4}, isbn = {1385-3449}, pages = {387 -- 393}, year = {2007}, language = {en} } @article{FerreinBeckLakemeyer2007, author = {Ferrein, Alexander and Beck, Daniel and Lakemeyer, Gerhard}, title = {A Simulation Environment for Middle-Size Robots with Multi-level Abstraction / Beck, Daniel ; Ferrein, Alexander ; Lakemeyer, Gerhard}, series = {RoboCup 2007: Robot Soccer World Cup XI}, journal = {RoboCup 2007: Robot Soccer World Cup XI}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-68846-4}, pages = {136 -- 147}, year = {2007}, language = {en} } @article{DachwaldBallUlamecetal.2009, author = {Dachwald, Bernd and Ball, Andrew J. and Ulamec, Stephan and Price, Michael E.}, title = {A small mission for in situ exploration of a primitive binary near-Earth asteroid / Ball, Andrew J. ; Ulamec, Stephan ; Dachwald, Bernd ; Price, Michael E. ; [u.a.]}, series = {Advances in Space Research. 43 (2009), H. 2}, journal = {Advances in Space Research. 43 (2009), H. 2}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0273-1177}, pages = {317 -- 324}, year = {2009}, language = {en} } @article{HillenAlperSelverFischeretal.2007, author = {Hillen, Walter and Alper Selver, M. and Fischer, Felix and Kuntalp, Mehmet}, title = {A software tool for interactive generation, representation, and systematical storage of transfer functions for 3D medical images / Alper Selver, M. ; Fischer, Felix ; Kuntalp, Mehmet ; Hillen, Walter}, series = {Computer Methods and Programs in Biomedicine. 86 (2007), H. 3}, journal = {Computer Methods and Programs in Biomedicine. 86 (2007), H. 3}, publisher = {-}, isbn = {0169-2607}, pages = {270 -- 280}, year = {2007}, language = {en} } @article{Weigand1991, author = {Weigand, Christoph}, title = {A Solution to the Scheduling Problem Taking into Account Quality}, series = {Operations research '91 : extended abstracts of the 16th Symposium on Operations Research held at the University of Trier at September 9 - 11, 1991 / [GM{\"O}OR]. Peter Gritzmann ... (eds.)}, journal = {Operations research '91 : extended abstracts of the 16th Symposium on Operations Research held at the University of Trier at September 9 - 11, 1991 / [GM{\"O}OR]. Peter Gritzmann ... (eds.)}, publisher = {Physica-Verl.}, address = {Heidelberg}, isbn = {3790806080}, pages = {373 -- 375}, year = {1991}, language = {en} } @article{MonakhovaDiehl2021, author = {Monakhova, Yulia and Diehl, Bernd W. K.}, title = {A step towards optimization of the qNMR workflow: proficiency testing exercise at an GxP-accredited laboratory}, series = {Applied Magnetic Resonance}, volume = {52}, journal = {Applied Magnetic Resonance}, publisher = {Springer Nature}, address = {Wien}, issn = {1613-7507}, doi = {10.1007/s00723-021-01324-3}, pages = {581 -- 593}, year = {2021}, abstract = {Quantitative nuclear magnetic resonance (qNMR) is considered as a powerful tool for multicomponent mixture analysis as well as for the purity determination of single compounds. Special attention is currently paid to the training of operators and study directors involved in qNMR testing. To assure that only qualified personnel are used for sample preparation at our GxP-accredited laboratory, weighing test was proposed. Sixteen participants performed six-fold weighing of the binary mixture of dibutylated hydroxytoluene (BHT) and 1,2,4,5-tetrachloro-3-nitrobenzene (TCNB). To evaluate the quality of data analysis, all spectra were evaluated manually by a qNMR expert and using in-house developed automated routine. The results revealed that mean values are comparable and both evaluation approaches are free of systematic error. However, automated evaluation resulted in an approximately 20\% increase in precision. The same findings were revealed for qNMR analysis of 32 compounds used in pharmaceutical industry. Weighing test by six-fold determination in binary mixtures and automated qNMR methodology can be recommended as efficient tools for evaluating staff proficiency. The automated qNMR method significantly increases throughput and precision of qNMR for routine measurements and extends application scope of qNMR.}, language = {en} } @article{ReisselBitschStamm2000, author = {Reißel, Martin and Bitsch, G. and Stamm, H.}, title = {A Stern Door Slam Fatigue Calculation / Bitsch, G. ; Reißel, M. ; Stamm, H.}, series = {Proceedings of the 18. CAD-FEM Users Meeting}, journal = {Proceedings of the 18. CAD-FEM Users Meeting}, year = {2000}, language = {en} } @article{FassbenderManeth1996, author = {Faßbender, Heinz and Maneth, Sebastian}, title = {A strict border for the decidability of e-unification for recursive functions / Faßbender, Heinz ; Maneth, Sebastian}, series = {Algebraic and logic programming : proceedings / 5th International Conference, ALP '96, Aachen, Germany, September 25 - 27, 1996. Michael Hanus ... (ed.)}, journal = {Algebraic and logic programming : proceedings / 5th International Conference, ALP '96, Aachen, Germany, September 25 - 27, 1996. Michael Hanus ... (ed.)}, publisher = {Springer}, address = {Berlin [u.a.]}, isbn = {3-540-61735-3}, pages = {194 -- 208}, year = {1996}, language = {en} } @article{FassbenderManeth1998, author = {Faßbender, Heinz and Maneth, Sebastian}, title = {A strict border for the decidability of e-unification for recursive functions / Faßbender, Heinz ; Maneth, Sebastian}, series = {Journal of functional and logic programming. 1998 (1998), H. 4}, journal = {Journal of functional and logic programming. 1998 (1998), H. 4}, isbn = {1080-5230}, year = {1998}, language = {en} } @article{Heuermann2004, author = {Heuermann, Holger}, title = {A Synthesis Technique for Mono- and Mixed-Mode Symmetrical Filter}, series = {Conference proceedings : Tuesday 12th, Wednesday 13th and Thursday 14th October, [RAI International Exhibition and Congress Centre, Amsterdam ; part of European Microwave Week 2004] / EuMA, European Microwave Association . Vol. 1}, journal = {Conference proceedings : Tuesday 12th, Wednesday 13th and Thursday 14th October, [RAI International Exhibition and Congress Centre, Amsterdam ; part of European Microwave Week 2004] / EuMA, European Microwave Association . Vol. 1}, publisher = {Horizon House Publ}, address = {London}, isbn = {1-580-53992-0}, pages = {309 -- 312}, year = {2004}, language = {en} } @article{WissenbachSixBongaertsetal.1995, author = {Wissenbach, U. and Six, S. and Bongaerts, Johannes and Ternes, D. and Steinwachs, S. and Unden, G.}, title = {A third periplasmic transport system for l-arginine in Escherichia coli: molecular characterization of the artPIQMJ genes, arginine binding and transport}, series = {Molecular microbiology}, volume = {Vol. 17}, journal = {Molecular microbiology}, number = {Iss. 4}, issn = {1365-2958 (E-Journal); 0950-382x (Print)}, pages = {675 -- 686}, year = {1995}, language = {en} } @article{GebhardtJarkeJacobs1997, author = {Gebhardt, Michael and Jarke, Matthias and Jacobs, Stephan}, title = {A Toolkit for Negotiation Support Interfaces to Multidimensional Data}, series = {SIGMOD 1997 : proceedings ACM SIGMOD International Conference on Management of Data, May 13 - 15, 1997, Tucson, Arizona, USA / ed. by Joan M. Peckman}, journal = {SIGMOD 1997 : proceedings ACM SIGMOD International Conference on Management of Data, May 13 - 15, 1997, Tucson, Arizona, USA / ed. by Joan M. Peckman}, publisher = {ACM Press}, address = {New York, NY}, isbn = {0897919114}, pages = {XIV, 586 S : Ill., graph. Darst.}, year = {1997}, language = {en} }