@article{DantismTakenagaWagneretal.2015, author = {Dantism, S. and Takenaga, S. and Wagner, P. and Wagner, Torsten and Sch{\"o}ning, Michael Josef}, title = {Light-addressable Potentiometric Sensor (LAPS) Combined with Multi-chamber Structures to Investigate the Metabolic Activity of Cells}, series = {Procedia Engineering}, volume = {120}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2015.08.647}, pages = {384 -- 387}, year = {2015}, abstract = {LAPS are field-effect-based potentiometric sensors which are able to monitor analyte concentrations in a spatially resolved manner. Hence, a LAPS sensor system is a powerful device to record chemical imaging of the concentration of chemical species in an aqueous solution, chemical reactions, or the growth of cell colonies on the sensor surface, to record chemical images. In this work, multi-chamber 3D-printed structures made out of polymer (PP-ABS) were combined with LAPS chips to analyse differentially and simultaneously the metabolic activity of Escherichia coli K12 and Chinese hamster ovary (CHO) cells, and the responds of those cells to the addition of glucose solution.}, language = {en} } @article{DankelmannHellwigVolkmann2009, author = {Dankelmann, Peter and Hellwig, Angelika and Volkmann, Lutz}, title = {Inverse degree and edge-connectivity}, series = {Discrete mathematics}, volume = {Vol. 309}, journal = {Discrete mathematics}, number = {Iss. 9}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1872-681X (E-Journal); 0012-365X (Print)}, pages = {2943 -- 2947}, year = {2009}, language = {en} } @article{DankelmannHellwigVolkmann2007, author = {Dankelmann, Peter and Hellwig, Angelika and Volkmann, Lutz}, title = {On the connectivity of diamond-free graphs}, series = {Discrete applied mathematics}, volume = {Vol. 155}, journal = {Discrete applied mathematics}, number = {Iss. 16}, issn = {0166-218X (E-Journal); 1872-6771 (E-Journal); 0166-218X (Print)}, pages = {2111 -- 2117}, year = {2007}, language = {en} } @article{DanhoNaithaniSasakietal.1980, author = {Danho, Waleed and Naithani, Vinod K. and Sasaki, Andr{\´e} N. and F{\"o}hles, Joseph and Berndt, Heinz and [u.a.],}, title = {Human proinsulin, VII : synthesis of two protected peptides corresponding to the sequences 1—45 and 46—86 of the prohormone}, series = {Hoppe-Seyler's Zeitschrift f{\"u}r physiologische Chemie}, volume = {361}, journal = {Hoppe-Seyler's Zeitschrift f{\"u}r physiologische Chemie}, number = {1}, issn = {1437-4315}, doi = {10.1515/bchm2.1980.361.1.857}, pages = {857 -- 863}, year = {1980}, language = {en} } @article{Damrau1999, author = {Damrau, Karin}, title = {Beyond Solidity - Inventions, Spaces and Concepts for the Elements of Air and Water}, series = {Architectural design : AD. 69 (1999), H. 3-4}, journal = {Architectural design : AD. 69 (1999), H. 3-4}, isbn = {0003-8504}, pages = {22 -- 33}, year = {1999}, language = {en} } @article{Damrau2000, author = {Damrau, Karin}, title = {Fantastic Spatial Combinations in Film}, series = {Architectural design : AD. 70 (2000), H. 1}, journal = {Architectural design : AD. 70 (2000), H. 1}, isbn = {0003-8504}, pages = {58 -- 61}, year = {2000}, language = {en} } @article{DammSauerbornFendetal.2017, author = {Damm, Marc Andr{\´e} and Sauerborn, Markus and Fend, Thomas and Herrmann, Ulf}, title = {Optimisation of a urea selective catalytic reduction system with a coated ceramic mixing element}, series = {Journal of ceramic science and technology}, volume = {8}, journal = {Journal of ceramic science and technology}, number = {1}, publisher = {G{\"o}ller}, address = {Baden-Baden}, isbn = {2190-9385 (Print)}, issn = {2190-9385 (Online)}, doi = {10.4416/JCST2016-00056}, pages = {19 -- 24}, year = {2017}, language = {en} } @article{DammErlerHillenetal.2011, author = {Damm, Alexander and Erler, Andr{\´e} and Hillen, Walter and Meroni, Michele and Schaepman, Michael E. and Verhoef, Wout and Rascher, Uwe}, title = {Modeling the impact of spectral sensor configurations on the FLD retrieval accuracy of sun-induced chlorophyll fluorescence}, series = {Remote Sensing of Environment}, volume = {115}, journal = {Remote Sensing of Environment}, number = {8}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {0034-4257}, pages = {1882 -- 1892}, year = {2011}, language = {en} } @article{DallasSalphatiGomezZepedaetal.2016, author = {Dallas, Shannon and Salphati, Laurent and Gomez-Zepeda, David and Wanek, Thomas and Chen, Liangfu and Chu, Xiaoyan and Kunta, Jeevan and Mezler, Mario and Menet, Marie-Claude and Chasseigneaux, Stephanie and Decl{\`e}ves, Xavier and Langer, Oliver and Pierre, Esaie and DiLoreto, Karen and Hoft, Carolin and Laplanche, Loic and Pang, Jodie and Pereira, Tony and Andonian, Clara and Simic, Damir and Rode, Anja and Yabut, Jocelyn and Zhang, Xiaolin and Scheer, Nico}, title = {Generation and Characterization of a Breast Cancer Resistance Protein Humanized Mouse Model}, series = {Molecular Pharmacology}, volume = {89}, journal = {Molecular Pharmacology}, number = {5}, publisher = {ASPET}, address = {Bethesda, Md.}, issn = {1521-0111}, doi = {10.1124/mol.115.102079}, pages = {492 -- 504}, year = {2016}, abstract = {Breast cancer resistance protein (BCRP) is expressed in various tissues, such as the gut, liver, kidney and blood brain barrier (BBB), where it mediates the unidirectional transport of substrates to the apical/luminal side of polarized cells. Thereby BCRP acts as an efflux pump, mediating the elimination or restricting the entry of endogenous compounds or xenobiotics into tissues and it plays important roles in drug disposition, efficacy and safety. Bcrp knockout mice (Bcrp-/-) have been used widely to study the role of this transporter in limiting intestinal absorption and brain penetration of substrate compounds. Here we describe the first generation and characterization of a mouse line humanized for BCRP (hBCRP), in which the mouse coding sequence from the start to stop codon was replaced with the corresponding human genomic region, such that the human transporter is expressed under control of the murine Bcrp promoter. We demonstrate robust human and loss of mouse BCRP/Bcrp mRNA and protein expression in the hBCRP mice and the absence of major compensatory changes in the expression of other genes involved in drug metabolism and disposition. Pharmacokinetic and brain distribution studies with several BCRP probe substrates confirmed the functional activity of the human transporter in these mice. Furthermore, we provide practical examples for the use of hBCRP mice to study drug-drug interactions (DDIs). The hBCRP mouse is a promising model to study the in vivo role of human BCRP in limiting absorption and BBB penetration of substrate compounds and to investigate clinically relevant DDIs involving BCRP.}, language = {en} } @article{DahmannMager1994, author = {Dahmann, Peter and Mager, M.}, title = {Einfluß der Zusammensetzung der abzuscheidenden Verschmutzung auf die Abscheideleistung von Hydraulikfiltern}, series = {{\"O}lhydraulik und Pneumatik. 38 (1994), H. 4}, journal = {{\"O}lhydraulik und Pneumatik. 38 (1994), H. 4}, isbn = {0341-2660}, pages = {212 -- 214}, year = {1994}, language = {de} } @article{DahmannHagemeisterNageletal.2006, author = {Dahmann, Peter and Hagemeister, Wilhelm and Nagel, G{\"u}nther and Exner, Peter}, title = {Geregelte Innenzahnradpumpe im Mehrquadrantenbetrieb Geschwindigkeits- und Positionsregelung eines hydraulischen Handlingger{\"a}tes}, series = {O+P {\"O}lhydraulik und Pneumatik. 24 (2006), H. 1}, journal = {O+P {\"O}lhydraulik und Pneumatik. 24 (2006), H. 1}, isbn = {0341-2660}, pages = {24 -- 28}, year = {2006}, language = {de} } @article{DahmannHagemeisterNageletal.2002, author = {Dahmann, Peter and Hagemeister, W. and Nagel, and Exner,}, title = {Geschwindigkeits- und Positionsregelung eines hydraulischen Handlingger{\"a}tes in einem Ziegelwerk durch frequenzgeregelte Innenzahnradpumpe im Mehrquadrantenbetrieb}, series = {Fluid power focused on applications : 3rd International Fluid Power Conference (3rd IFK) ; [conference proceedings, March 5th and 6th 2002, Aachen, Germany]. Fluidtechnik, Band T3}, journal = {Fluid power focused on applications : 3rd International Fluid Power Conference (3rd IFK) ; [conference proceedings, March 5th and 6th 2002, Aachen, Germany]. Fluidtechnik, Band T3}, publisher = {Shaker}, address = {Aachen}, isbn = {3-8265-9900-4}, pages = {83 -- 94}, year = {2002}, language = {de} } @article{Dahmann1995, author = {Dahmann, Peter}, title = {Offen f{\"u}r neue Modelle. GL-Hydraulik setzt neues Simulationssystem ein}, series = {Fluid Heft Sonderpublikation Fluid-Technik. 29 (1995)}, journal = {Fluid Heft Sonderpublikation Fluid-Technik. 29 (1995)}, isbn = {0015-461X}, pages = {8 -- 10}, year = {1995}, language = {de} } @article{Dahmann1990, author = {Dahmann, Peter}, title = {Leistungsf{\"a}higkeit von Hydraulikfiltern bei unterschiedlichen Betriebsbedingungen}, series = {{\"O}lhydraulik und Pneumatik. 34 (1990), H. 10}, journal = {{\"O}lhydraulik und Pneumatik. 34 (1990), H. 10}, isbn = {0341-2660}, pages = {682 -- 688}, year = {1990}, language = {de} } @article{Dahmann1993, author = {Dahmann, Peter}, title = {Funktionsweise von Hydraulikfiltern}, series = {{\"O}lhydraulik und Pneumatik. 37 (1993), H. 2}, journal = {{\"O}lhydraulik und Pneumatik. 37 (1993), H. 2}, isbn = {0341-2660}, pages = {118 -- 122}, year = {1993}, language = {de} } @article{DahlSuttrop1998, author = {Dahl, G{\"u}nter and Suttrop, F.}, title = {Engine control and low-NO(x) combustion for hydrogen fuelled aircraft gas turbines}, series = {International Journal of Hydrogen Energy. 23 (1998), H. 8}, journal = {International Journal of Hydrogen Energy. 23 (1998), H. 8}, isbn = {0360-3199}, pages = {695 -- 704}, year = {1998}, language = {en} } @article{DadfarCamozziDarguzyteetal.2020, author = {Dadfar, Dryed Mohammadali and Camozzi, Denise and Darguzyte, Milita and Roemhild, Karolin and Varvar{\`a}, Paola and Metselaar, Josbert and Banala, Srinivas and Straub, Marcel and G{\"u}ver, Nihan and Engelmann, Ulrich M. and Slabu, Ioana and Buhl, Miriam and Leusen, Jan van and K{\"o}gerler, Paul and Hermanns-Sachweh, Benita and Schulz, Volkmar and Kiessling, Fabian and Lammers, Twan}, title = {Size-isolation of superparamagnetic iron oxide nanoparticles improves MRI, MPI and hyperthermia performance}, series = {Journal of Nanobiotechnology}, volume = {18}, journal = {Journal of Nanobiotechnology}, number = {Article number 22}, publisher = {Nature Portfolio}, issn = {1477-3155}, doi = {10.1186/s12951-020-0580-1}, pages = {1 -- 13}, year = {2020}, abstract = {Superparamagnetic iron oxide nanoparticles (SPION) are extensively used for magnetic resonance imaging (MRI) and magnetic particle imaging (MPI), as well as for magnetic fluid hyperthermia (MFH). We here describe a sequential centrifugation protocol to obtain SPION with well-defined sizes from a polydisperse SPION starting formulation, synthesized using the routinely employed co-precipitation technique. Transmission electron microscopy, dynamic light scattering and nanoparticle tracking analyses show that the SPION fractions obtained upon size-isolation are well-defined and almost monodisperse. MRI, MPI and MFH analyses demonstrate improved imaging and hyperthermia performance for size-isolated SPION as compared to the polydisperse starting mixture, as well as to commercial and clinically used iron oxide nanoparticle formulations, such as Resovist® and Sinerem®. The size-isolation protocol presented here may help to identify SPION with optimal properties for diagnostic, therapeutic and theranostic applications.}, language = {en} } @article{DachwaldWurm2011, author = {Dachwald, Bernd and Wurm, Patrick}, title = {Mission analysis and performance comparison for an Advanced Solar Photon Thruster}, series = {Advances in Space Research}, volume = {48}, journal = {Advances in Space Research}, number = {11}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0273-1177}, pages = {1858 -- 1868}, year = {2011}, language = {en} } @article{DachwaldWie2005, author = {Dachwald, Bernd and Wie, Bong}, title = {Solar Sail Trajectory Optimization for Intercepting, Impacting, and Deflecting Near-Earth Asteroids}, series = {AIAA Guidance, Navigation and Control Conference and Exhibit - AIAA Modeling and Simulation Technologies Conference and Exhibit - AIAA Atmospheric Flight Mechanics Conference and Exhibit : [San Francisco, California, 15 - 18 August 2005 ; papers]. - (AIAA meeting papers on disc ; [10.]2005,16-17)}, journal = {AIAA Guidance, Navigation and Control Conference and Exhibit - AIAA Modeling and Simulation Technologies Conference and Exhibit - AIAA Atmospheric Flight Mechanics Conference and Exhibit : [San Francisco, California, 15 - 18 August 2005 ; papers]. - (AIAA meeting papers on disc ; [10.]2005,16-17)}, publisher = {American Institute of Aeronautics and Astronautics}, address = {Reston, Va.}, isbn = {1-56347-765-3}, pages = {2 CD-ROMs}, year = {2005}, language = {en} } @article{DachwaldWi2007, author = {Dachwald, Bernd and Wi, Bong}, title = {Solar Sail Kinetic Energy Impactor Trajectory Optimization for an Asteroid-Deflection Mission}, series = {Journal of Spacecraft and Rockets. 44 (2007), H. 4}, journal = {Journal of Spacecraft and Rockets. 44 (2007), H. 4}, isbn = {0022-4650}, pages = {755 -- 764}, year = {2007}, language = {en} }