@article{ScheerKapelyukhMcEwanetal.2012, author = {Scheer, Nico and Kapelyukh, Yury and McEwan, Jillian and Beuger, Vincent and Stanley, Lesley A. and Rode, Anja and Wolf, C. Roland}, title = {Modeling Human Cytochrome P450 2D6 Metabolism and Drug-drug Interaction by a Novel Panel of Knockout and Humanized Mouse Lines}, series = {Molecular Pharmacology}, volume = {81}, journal = {Molecular Pharmacology}, number = {1}, publisher = {ASPET}, address = {Bethesda, Md.}, issn = {1521-0111}, doi = {10.1124/mol.111.075192}, pages = {63 -- 72}, year = {2012}, abstract = {The highly polymorphic human cytochrome P450 2D6 enzyme is involved in the metabolism of up to 25\% of all marketed drugs and accounts for significant individual differences in response to CYP2D6 substrates. Because of the differences in the multiplicity and substrate specificity of CYP2D family members among species, it is difficult to predict pathways of human CYP2D6-dependent drug metabolism on the basis of animal studies. To create animal models that reflect the human situation more closely and that allow an in vivo assessment of the consequences of differential CYP2D6 drug metabolism, we have developed a novel straightforward approach to delete the entire murine Cyp2d gene cluster and replace it with allelic variants of human CYP2D6. By using this approach, we have generated mouse lines expressing the two frequent human protein isoforms CYP2D6.1 and CYP2D6.2 and an as yet undescribed variant of this enzyme, as well as a Cyp2d cluster knockout mouse. We demonstrate that the various transgenic mouse lines cover a wide spectrum of different human CYP2D6 metabolizer phenotypes. The novel humanization strategy described here provides a robust approach for the expression of different CYP2D6 allelic variants in transgenic mice and thus can help to evaluate potential CYP2D6-dependent interindividual differences in drug response in the context of personalized medicine.}, language = {en} } @article{VogtIwanowskiStrahserMarquartetal.2013, author = {Vogt, Christian and Iwanowski-Strahser, Katha and Marquart, Gabriele and Arnold, Juliane and Mottaghy, Darius and Pechnig, Renate and Gnjezda, Daniel and Clauser, Christoph}, title = {Modeling contribution to risk assessment of thermal production power for geothermal reservoirs}, series = {Renewable Energy}, volume = {53}, journal = {Renewable Energy}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0960-1481}, doi = {10.1016/j.renene.2012.11.026}, pages = {230 -- 241}, year = {2013}, language = {en} } @article{JungStaat2019, author = {Jung, Alexander and Staat, Manfred}, title = {Modeling and simulation of human induced pluripotent stem cell-derived cardiac tissue}, series = {GAMM - Mitteilungen der Gesellschaft f{\"u}r Angewandte Mathematik und Mechanik}, volume = {42}, journal = {GAMM - Mitteilungen der Gesellschaft f{\"u}r Angewandte Mathematik und Mechanik}, number = {4}, publisher = {Wiley}, address = {Weinheim}, issn = {1522-2608}, doi = {10.1002/gamm.201900002}, pages = {11 Seiten}, year = {2019}, language = {en} } @article{RiekeStollenwerkDahmenetal.2018, author = {Rieke, Christian and Stollenwerk, Dominik and Dahmen, Markus and Pieper, Martin}, title = {Modeling and optimization of a biogas plant for a demand-driven energy supply}, series = {Energy}, volume = {145}, journal = {Energy}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0360-5442}, doi = {10.1016/j.energy.2017.12.073}, pages = {657 -- 664}, year = {2018}, abstract = {Due to the Renewable Energy Act, in Germany it is planned to increase the amount of renewable energy carriers up to 60\%. One of the main problems is the fluctuating supply of wind and solar energy. Here biogas plants provide a solution, because a demand-driven supply is possible. Before running such a plant, it is necessary to simulate and optimize the process. This paper provides a new model of a biogas plant, which is as accurate as the standard ADM1 model. The advantage compared to ADM1 is that it is based on only four parameters compared to 28. Applying this model, an optimization was installed, which allows a demand-driven supply by biogas plants. Finally the results are confirmed by several experiments and measurements with a real test plant.}, language = {en} } @article{BehbahaniMaiBergmannetal.2010, author = {Behbahani, Mehdi and Mai, A. and Bergmann, B. and Waluga, C. and Behr, M. and Tran, L. and Vonderstein, K. and Mottaghy, K.}, title = {Modeling and Numerical Simulation of Blood Damage}, year = {2010}, language = {en} } @article{BehbahaniNamWalugaetal.2010, author = {Behbahani, Mehdi and Nam, J. and Waluga, C. and Behr, M. and Pasquali, M. and Mottaghy, K.}, title = {Modeling and Numerical Analysis of Platelet Activation, Adhesion and Aggregation in Artificial Organs}, doi = {10.1097/01.mat.0000369377.65122.a3}, year = {2010}, language = {en} } @article{SchaeferHeil2002, author = {Sch{\"a}fer, Horst and Heil, G{\"u}nter}, title = {Modeling and Graphic Presentation of Acid-Base Titration Curves. Presentation of an Alternative Method}, series = {The Chemical Educator. 7 (2002), H. 6}, journal = {The Chemical Educator. 7 (2002), H. 6}, isbn = {1430-4171}, pages = {339 -- 346}, year = {2002}, language = {en} } @article{BehbahaniTranWalugaetal.2009, author = {Behbahani, Mehdi and Tran, L. and Waluga, C. and Behr, M. and Oedekoven, B. and Mottaghy, K.}, title = {Model-based Numerical Analysis of Platelet Adhesion, Thrombus Growth and Aggregation for Assist Devices}, series = {The International Journal of Artificial Organs. 32 (2009), H. 7}, journal = {The International Journal of Artificial Organs. 32 (2009), H. 7}, isbn = {0391-3988}, pages = {398 -- 398}, year = {2009}, language = {en} } @article{KotliarBauerZamuraev2006, author = {Kotliar, Konstantin and Bauer, S. M. and Zamuraev, L. A.}, title = {Model of the transversely isotropic spherical layer for estimation of intraocular pressure changes after intravitreal injections / Bauer, S. M. ; Zamuraev, L. A. ; Kotliar, K. E.}, series = {Rossiiskii zhurnal biomekhaniki = Russian Journal of biomechanics. 10 (2006), H. 2}, journal = {Rossiiskii zhurnal biomekhaniki = Russian Journal of biomechanics. 10 (2006), H. 2}, publisher = {-}, isbn = {1812-5123}, pages = {41 -- 47}, year = {2006}, language = {en} } @article{FoersterZamdmerHuetal.1999, author = {F{\"o}rster, Arnold and Zamdmer, N. and Hu, Qing and Verghese, S.}, title = {Mode-Discriminating Photoconductor and Coplanar Wave-Guide Circuits for Picosecond Sampling. Zamdmer, N.; Hu, Qing ; Verghese, S. ; F{\"o}rster, A.}, series = {Applied Physics Letters. 74 (1999), H. 7}, journal = {Applied Physics Letters. 74 (1999), H. 7}, isbn = {1077-3118}, pages = {1039 -- 1041}, year = {1999}, language = {en} } @article{WallenbornRitz2014, author = {Wallenborn, Ramona and Ritz, Thomas}, title = {Mobilit{\"a}t miteinander teilen : st{\"a}dtisches eCarsharing in einer vernetzten Gesellschaft ; [vernetztes Fahren von morgen]}, series = {Neue Mobilit{\"a}t : das Magazin vom Bundesverband eMobilit{\"a}t}, volume = {5}, journal = {Neue Mobilit{\"a}t : das Magazin vom Bundesverband eMobilit{\"a}t}, number = {14 (Herbstausg.)}, publisher = {Bundesverband eMobilit{\"a}t BEM}, address = {Berlin}, issn = {2191-5636}, pages = {92 -- 95}, year = {2014}, language = {de} } @article{RitzStender2002, author = {Ritz, Thomas and Stender, Michael}, title = {Mobilit{\"a}t meistern - Integration von mobilen Akteuren durch ad-hoc Integrationskonzepte}, series = {Wireless Technologien nutzbar machen: UMTS und alternative Netzwerktechnologien f{\"u}r innovative mobile Anwendungen in Vertrieb und Service}, journal = {Wireless Technologien nutzbar machen: UMTS und alternative Netzwerktechnologien f{\"u}r innovative mobile Anwendungen in Vertrieb und Service}, year = {2002}, language = {de} } @article{Ritz2006, author = {Ritz, Thomas}, title = {Mobile Unternehmenssoftware}, series = {Das Wirtschaftsstudium : wisu ; Zeitschrift f{\"u}r Ausbildung, Examen, Berufseinstieg und Weiterbildung}, volume = {36}, journal = {Das Wirtschaftsstudium : wisu ; Zeitschrift f{\"u}r Ausbildung, Examen, Berufseinstieg und Weiterbildung}, number = {10}, isbn = {0340-3084}, pages = {1212 -- 1218}, year = {2006}, language = {de} } @article{HartungHornHuschkeetal.2007, author = {Hartung, Frank and Horn, Uwe and Huschke, J{\"o}rg and Kampmann, Markus}, title = {Mobile TV Services in 3G Networks / Hartung, Frank ; Horn, Uwe ; Huschke, J{\"o}rg ; Kampmann, Markus ; Lohmar, Thorsten}, series = {KIVS 2007 : Kommunikation in verteilten Systemen : 15. ITG-GI-Fachtagung vom 26. Februar bis 2. M{\"a}rz 2007 in Bern, Schweiz ; Industriebeitr{\"a}ge, Kurzbeitr{\"a}ge und Workshops / T. Braun ... (Hrsg.)}, journal = {KIVS 2007 : Kommunikation in verteilten Systemen : 15. ITG-GI-Fachtagung vom 26. Februar bis 2. M{\"a}rz 2007 in Bern, Schweiz ; Industriebeitr{\"a}ge, Kurzbeitr{\"a}ge und Workshops / T. Braun ... (Hrsg.)}, isbn = {978-3-8007-2980-7}, pages = {15 -- 18}, year = {2007}, language = {en} } @article{HartungKampmannHornetal.2007, author = {Hartung, Frank and Kampmann, Markus and Horn, Uwe and Kritzner, Jan}, title = {Mobile Television / Hartung, Frank ; Kampmann, Markus ; Horn, Uwe ; Kritzner, Jan}, series = {Encyclopedia of mobile computing and commerce / David Taniar ; Bd. 2 : Mobile ICT - Z}, journal = {Encyclopedia of mobile computing and commerce / David Taniar ; Bd. 2 : Mobile ICT - Z}, publisher = {Information Science Reference}, address = {Hershey}, isbn = {978-1-59904-002-8}, pages = {611 -- 615}, year = {2007}, language = {en} } @article{SchubaWronaZavagli2001, author = {Schuba, Marko and Wrona, Konrad and Zavagli, Guido}, title = {Mobile Payments - State of the Art and Open Problems / Wrona, Konrad ; Schuba, Marko ; Zavagli, Guido}, series = {Electronic commerce : second international workshop ; proceedings / WELCOM 2001, Heidelberg, Germany, November 16-17, 2001. Ludger Fiege ... (ed.)}, journal = {Electronic commerce : second international workshop ; proceedings / WELCOM 2001, Heidelberg, Germany, November 16-17, 2001. Ludger Fiege ... (ed.)}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-42878-7}, pages = {88 -- 100}, year = {2001}, language = {en} } @article{Hartung2003, author = {Hartung, Frank}, title = {Mobile DRM Introduction: The Need for Mobile DRM}, series = {Digital Rights Management : Technological, Economic, Legal and Political Aspects / Becker, Eberhard [u.a.]}, journal = {Digital Rights Management : Technological, Economic, Legal and Political Aspects / Becker, Eberhard [u.a.]}, publisher = {Springer}, address = {Berlin}, pages = {138 -- 149}, year = {2003}, language = {en} } @article{Ritz2003, author = {Ritz, Thomas}, title = {Mobile CRM-Systeme : Customer Relationship Management zur Unterst{\"u}tzung des Vertriebsaußendienstes}, series = {Zeitschrift f{\"u}r wirtschaftlichen Fabrikbetrieb : ZWF ; Organ des VDI-Kompetenzfeldes Informationstechnik (VDI-KfIT)}, volume = {99}, journal = {Zeitschrift f{\"u}r wirtschaftlichen Fabrikbetrieb : ZWF ; Organ des VDI-Kompetenzfeldes Informationstechnik (VDI-KfIT)}, number = {12}, issn = {0932-0482 (Print)}, pages = {699 -- 702}, year = {2003}, language = {de} } @article{SchubaWrona2000, author = {Schuba, Marko and Wrona, Konrad}, title = {Mobile Chip Electronic Commerce: Enabling Credit Card Payment for Mobile Devices / Schuba, Marko ; Wrona, Konrad}, pages = {1 -- 6}, year = {2000}, language = {en} } @article{Benkner2000, author = {Benkner, Thorsten}, title = {Mobile Breitband-Zugangstechniken f{\"u}r ATM-Netze}, series = {Konvergenz im Bereich der Telekommunikation. Beitr{\"a}ge der Invited Speakers und aus dem Call for Papers der gleichnamigen Tagung an der TU Graz}, journal = {Konvergenz im Bereich der Telekommunikation. Beitr{\"a}ge der Invited Speakers und aus dem Call for Papers der gleichnamigen Tagung an der TU Graz}, publisher = {Eigenverl. d. {\"O}sterr. Verb. f{\"u}r Elektrotechnik}, address = {Wien}, isbn = {3-85133-021-8}, year = {2000}, language = {de} }