@incollection{WolfKapelyukhScheeretal.2015, author = {Wolf, C. Roland and Kapelyukh, Yury and Scheer, Nico and Henderson, Colin J.}, title = {Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs}, editor = {Wilson, Alan G. E.}, publisher = {RSC Publ.}, address = {Cambridge}, isbn = {978-1-78262-778-4}, doi = {10.1039/9781782622376-00152}, pages = {152 -- 176}, year = {2015}, abstract = {The use of transgenic animal models has transformed our knowledge of complex biochemical pathways in vivo. It has allowed disease processes to be modelled and used in the development of new disease prevention and treatment strategies. They can also be used to define cell- and tissue-specific pathways of gene regulation. A further major application is in the area of preclinical development where such models can be used to define pathways of chemical toxicity, and the pathways that regulate drug disposition. One major application of this approach is the humanisation of mice for the proteins that control drug metabolism and disposition. Such models can have numerous applications in the development of drugs and in their more sophisticated use in the clinic.}, language = {en} } @incollection{ScheerChuSalphatietal.2016, author = {Scheer, Nico and Chu, Xiaoyan and Salphati, Laurent and Zamek-Gliszczynski, Maciej J.}, title = {Knockout and humanized animal models to study membrane transporters in drug development}, series = {Drug Transporters: Volume 1: Role and Importance in ADME and Drug Development}, booktitle = {Drug Transporters: Volume 1: Role and Importance in ADME and Drug Development}, editor = {Nicholls, Glynis}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, isbn = {978-1-78262-379-3}, doi = {10.1039/9781782623793-00298}, pages = {298 -- 332}, year = {2016}, language = {en} } @incollection{SamuelssonScheerWilsonetal.2017, author = {Samuelsson, K. and Scheer, Nico and Wilson, I. and Wolf, C.R. and Henderson, C.J.}, title = {Genetically Humanized Animal Models}, series = {Comprehensive Medicinal Chemistry III. 3rd Edition}, booktitle = {Comprehensive Medicinal Chemistry III. 3rd Edition}, editor = {Chackalamannil, Samuel}, publisher = {Elsevier}, address = {Saint Louis}, isbn = {978-0-12-803201-5}, doi = {10.1016/B978-0-12-409547-2.12376-5}, pages = {130 -- 149}, year = {2017}, abstract = {Genetically humanized mice for proteins involved in drug metabolism and toxicity and mice engrafted with human hepatocytes are emerging as promising in vivo models for improved prediction of the pharmacokinetic, drug-drug interaction, and safety characteristics of compounds in humans. This is an overview on the genetically humanized and chimeric liver-humanized mouse models, which are illustrated with examples of their utility in drug metabolism and toxicity studies. The models are compared to give guidance for selection of the most appropriate model by highlighting advantages and disadvantages to be carefully considered when used for studies in drug discovery and development.}, language = {en} } @incollection{Eggert2019, author = {Eggert, Mathias}, title = {Big Data Research - How to Structure the Changes of the Past Decade?}, series = {The Art of Structuring}, booktitle = {The Art of Structuring}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-06234-7}, doi = {10.1007/978-3-030-06234-7_26}, pages = {271 -- 281}, year = {2019}, abstract = {In the past decade, many IS researchers focused on researching the phenomenon of Big Data. At the same time, the relevance of data protection gets more attention than ever before. In particular, since the enactment of the European General Data Protection Regulation in May 2018 Information Systems research should provide answers for protecting personal data. The article at hand presents a structuring framework for Big Data research outcome and the consideration of data protection. IS Researchers might use the framework in order to structure Big Data literature and to identify research gaps that should be addressed in the future.}, language = {en} } @incollection{FranzenSteckenPfaffetal.2019, author = {Franzen, Julian and Stecken, Jannis and Pfaff, Raphael and Kuhlenk{\"o}tter, Bernd}, title = {Using the Digital Shadow for a Prescriptive Optimization of Maintenance and Operation : The Locomotive in the Context of the Cyber-Physical System}, series = {Advances in Production, Logistics and Traffic}, booktitle = {Advances in Production, Logistics and Traffic}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-13535-5}, doi = {10.1007/978-3-030-13535-5_19}, pages = {265 -- 276}, year = {2019}, abstract = {In competition with other modes of transport, rail freight transport is looking for solutions to become more attractive. Short-term success can be achieved through the data-driven optimization of operations and maintenance as well as the application of novel strategies such as prescriptive maintenance. After introducing the concept of prescriptive maintenance, this paper aims to prove that vehicle-focused applications of this approach indeed have the potential to increase attractiveness. However, even greater advantages can be activated if data from the horizontal network of the vehicle is available. Drawing on the state of the art in research and technology in the field of cyber-physical systems (CPS) as well as digital twins and shadows, our work serves to design a system of systems for the horizontal interconnection of a rail vehicle and to conceptualize a draft for a digital twin of a locomotive.}, language = {en} } @incollection{BosseBarnat2019, author = {Bosse, Elke and Barnat, Miriam}, title = {Kombination quantitativer und qualitativer Methoden zur Untersuchung der Studieneingangsphase}, series = {Hochschulbildungsforschung. Theoretische, methodologische und methodische Denkanst{\"o}ße f{\"u}r die Hochschuldidaktik}, booktitle = {Hochschulbildungsforschung. Theoretische, methodologische und methodische Denkanst{\"o}ße f{\"u}r die Hochschuldidaktik}, editor = {Jenert, Tobias and Reinmann, Gabi and Schmohl, Tobias}, publisher = {Springer VS}, address = {Wiesbaden}, isbn = {978-3-658-20308-5}, pages = {169 -- 184}, year = {2019}, language = {de} } @incollection{DrummLemckeOberle2007, author = {Drumm, Christian and Lemcke, Jens and Oberle, Daniel}, title = {Business Process Management And Semantic Technologies}, series = {The Semantic Web}, booktitle = {The Semantic Web}, publisher = {Springer}, address = {Boston, MA}, isbn = {978-0-387-48531-7}, doi = {10.1007/978-0-387-48531-7_10}, pages = {207 -- 239}, year = {2007}, language = {en} } @incollection{RoethDeutskensKreiskoetheretal.2018, author = {R{\"o}th, Thilo and Deutskens, Christoph and Kreisk{\"o}ther, Kai and Heimes, Heiner Hans and Schittny, Bastian and Ivanescu, Sebastian and Kleine B{\"u}ning, Max and Reinders, Christian and Wessels, Saskia and Haunreiter, Andreas and Reisgen, Uwe and Thiele, Regina and Hameyer, Kay and Doncker, Rik W. de and Sauer, Uwe and Hoek, Hauke van and H{\"u}bner, Mareike and Hennen, Martin and Stolze, Thilo and Vetter, Andreas and Hagedorn, J{\"u}rgen and M{\"u}ller, Dirk and Rewitz, Kai and Wesseling, Mark and Flieger, Bj{\"o}rn}, title = {Entwicklung von elektrofahrzeugspezifischen Systemen}, series = {Elektromobilit{\"a}t}, booktitle = {Elektromobilit{\"a}t}, publisher = {Springer Vieweg}, address = {Berlin, Heidelberg}, isbn = {978-3-662-53137-2}, doi = {10.1007/978-3-662-53137-2_6}, pages = {279 -- 386}, year = {2018}, abstract = {Die Batterie ist eine der absolut zentralen Komponenten des Elektrofahrzeugs. Die serielle Entwicklung und Produktion dieser Batterien und die Verbesserung der Leistungen wird entscheidend f{\"u}r den Erfolg der Elektromobilit{\"a}t sein. Die Batterie ist jedoch nicht das einzige elektrofahrzeugspezifische System, das neu entwickelt, umkonzipiert oder verbessert werden muss. So sind ebenso die Entwicklung der neuen Fahrzeugstruktur sowie des elektrifizierten Antriebsstranges Teil dieses Kapitels. Weiterhin wird ein Blick auf das bedeutende Thema des Thermomanagements geworfen.}, language = {de} } @incollection{KrollLudwigs2015, author = {Kroll-Ludwigs, Kathrin}, title = {Art. 5 Rom III-Regulation (choice of applicable law by the parties)}, series = {Rome Regulations : commentary}, booktitle = {Rome Regulations : commentary}, editor = {Calliess, Gralf-Peter}, edition = {2nd ed.}, publisher = {Wolters Kluwer}, isbn = {9789041147547}, year = {2015}, language = {en} } @incollection{KrollLudwigs2015, author = {Kroll-Ludwigs, Kathrin}, title = {Art. 7 Rome III-Regulation (formal validity)}, series = {Rome Regulations : commentary}, booktitle = {Rome Regulations : commentary}, editor = {Colliess, Gralf-Peter}, edition = {2nd ed.}, publisher = {Wolters Kluwer}, isbn = {9789041147547}, year = {2015}, language = {en} } @incollection{CalliessKrollLudwigs2015, author = {Calliess, Gralf-Peter and Kroll-Ludwigs, Kathrin}, title = {Art. 6 Rome III-Regulation (consent and material validity)}, series = {Rome Regulations : commentary}, booktitle = {Rome Regulations : commentary}, publisher = {Wolters Kluwer}, isbn = {9789041147547}, year = {2015}, language = {en} } @incollection{BarnatJaensch2019, author = {Barnat, Miriam and J{\"a}nsch, Vanessa K.}, title = {Forschendes Lernen und Studienerfolg: Die Bedeutung epistemischer Neugier}, series = {Forschendes Lernen in der Studieneingangsphase: Empirische Befunde, Fallbeispiele und individuelle Perspektiven}, booktitle = {Forschendes Lernen in der Studieneingangsphase: Empirische Befunde, Fallbeispiele und individuelle Perspektiven}, publisher = {Springer VS}, address = {Wiesbaden}, isbn = {978-3-658-25312-7}, doi = {10.1007/978-3-658-25312-7_6}, pages = {99 -- 109}, year = {2019}, abstract = {Forschendes Lernen ist dazu geeignet, epistemische Neugier - definiert als Freude an neuen Erkenntnissen - anzuregen und zu befriedigen. Neben der Selbstwirksamkeit zeigt sich die Neugier als relevant f{\"u}r den Studienerfolg. Allerdings ist bisher nicht gekl{\"a}rt, in welcher Beziehung diese beiden Konstrukte zueinanderstehen.}, language = {de} } @incollection{KrollLudwigs2017, author = {Kroll-Ludwigs, Kathrin}, title = {Small Claims Regulation}, series = {European Encyclopedia of Private International Law}, booktitle = {European Encyclopedia of Private International Law}, publisher = {Edward Elgar Publishing}, address = {Cheltenham, UK}, isbn = {9781782547228}, year = {2017}, language = {en} } @incollection{KrollLudwigs2017, author = {Kroll-Ludwigs, Kathrin}, title = {Names of individuals}, series = {European Encyclopedia of Private International Law}, booktitle = {European Encyclopedia of Private International Law}, publisher = {Edward Elgar Publishing}, address = {Cheltenham, UK}, isbn = {9781782547228}, year = {2017}, language = {en} } @incollection{KrollLudwigs2017, author = {Kroll-Ludwigs, Kathrin}, title = {Art. 48 EGBGB: Wahl eines in einem anderen Mitgliedstaat der Europ{\"a}ischen Union erworbenen Namens, Rn. 5-8, Rn. 11-14, Rn. 45-47, Rn. 48-51}, series = {Beck'scher Online-Großkommentar zum B{\"u}rgerlichen Recht (BeckOGK), Band: Internationales Privatrecht}, booktitle = {Beck'scher Online-Großkommentar zum B{\"u}rgerlichen Recht (BeckOGK), Band: Internationales Privatrecht}, editor = {Weller, Marc-Philippe and Kindler, Peter}, publisher = {C.H.Beck}, address = {M{\"u}nchen}, year = {2017}, language = {de} } @incollection{KrollLudwigs2017, author = {Kroll-Ludwigs, Kathrin}, title = {Kommentierung zu \S\S 1852 - 1857a}, series = {M{\"u}nchener Kommentar zum BGB Band 9, Familienrecht II}, booktitle = {M{\"u}nchener Kommentar zum BGB Band 9, Familienrecht II}, edition = {7. Auflage}, publisher = {C.H.Beck}, address = {M{\"u}nchen}, isbn = {978-3-406-66548-6}, year = {2017}, language = {de} } @incollection{KrollLudwigs2017, author = {Kroll-Ludwigs, Kathrin}, title = {Kommentierung zu \S\S 1837 - 1851}, series = {M{\"u}nchener Kommentar zum BGB Band 9, Familienrecht II}, booktitle = {M{\"u}nchener Kommentar zum BGB Band 9, Familienrecht II}, edition = {7. Auflage}, publisher = {C.H.Beck}, address = {M{\"u}nchen}, isbn = {978-3-406-66548-6}, year = {2017}, language = {de} } @incollection{KrollLudwigs2017, author = {Kroll-Ludwigs, Kathrin}, title = {Kommentierung zu \S\S 1802 - 1834}, series = {M{\"u}nchener Kommentar zum BGB Band 9, Familienrecht II}, booktitle = {M{\"u}nchener Kommentar zum BGB Band 9, Familienrecht II}, editor = {Oetker, Hartmut and Rixecker, Roland and S{\"a}cker, J{\"u}rgen}, edition = {7. Auflage}, publisher = {C.H.Beck}, address = {M{\"u}nchen}, isbn = {978-3-406-66548-6}, year = {2017}, language = {de} } @incollection{KrollLudwigs2015, author = {Kroll-Ludwigs, Kathrin}, title = {Kommentierung zu EU-LP-G{\"u}terVO}, series = {Europ{\"a}isches Zivilprozess- und Kollisionsrecht EuZPR/EuIPR, Band IV}, booktitle = {Europ{\"a}isches Zivilprozess- und Kollisionsrecht EuZPR/EuIPR, Band IV}, editor = {Rauscher, Thomas}, edition = {4., neu bearbeitete Auflage}, publisher = {Verlag Dr. Otto Schmidt}, address = {K{\"o}ln}, isbn = {978-3-504-38437-1}, doi = {10.9785/9783504384371-008}, pages = {1147 -- 1188}, year = {2015}, language = {de} } @incollection{KrollLudwigs2015, author = {Kroll-Ludwigs, Kathrin}, title = {Kommentierung zu EU-EheG{\"u}terVO-E}, series = {Europ{\"a}isches Zivilprozess- und Kollisionsrecht EuZPR/EuIPR, Band IV}, booktitle = {Europ{\"a}isches Zivilprozess- und Kollisionsrecht EuZPR/EuIPR, Band IV}, editor = {Rauscher, Thomas}, edition = {4., neu bearbeitete Auflage}, publisher = {Verlag Dr. Otto Schmidt}, address = {K{\"o}ln}, isbn = {978-3-504-38437-1}, doi = {10.9785/9783504384371-007}, pages = {1081 -- 1146}, year = {2015}, language = {de} }