@article{GuoSekiMiyamotoetal.2014, author = {Guo, Yuanyuan and Seki, Kosuke and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Device simulation of the light-addressable potentiometric sensor with a novel photoexcitation method for a higher spatial resolution}, series = {Procedia Engineering}, volume = {87}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2014.11.369}, pages = {456 -- 459}, year = {2014}, abstract = {A novel photoexcitation method for the light-addressable potentiometric sensor (LAPS) realized a higher spatial resolution of chemical imaging. In this method, a modulated light probe, which generates the alternating photocurrent signal, is surrounded by a ring of constant light, which suppresses the lateral diffusion of photocarriers by enhancing recombination. A device simulation verified that a higher spatial resolution could be obtained by adjusting the gap between the modulated and constant light. It was also found that a higher intensity and a longer wavelength of constant light was more effective. However, there exists a tradeoff between the spatial resolution and the amplitude of the photocurrent, and thus, the signal-to-noise ratio. A tilted incidence of constant light was applied, which could achieve even higher resolution with a smaller loss of photocurrent.}, language = {en} } @article{SchusserBaeckerKrischeretal.2014, author = {Schusser, Sebastian and B{\"a}cker, Matthias and Krischer, M. and Wenzel, L. and Leinhos, Marcel and Poghossian, Arshak and Biselli, Manfred and Wagner, P. and Sch{\"o}ning, Michael Josef}, title = {Enzymatically catalyzed degradation of biodegradable polymers investigated by means of a semiconductor-based field-effect sensor}, series = {Procedia Engineering}, volume = {87}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2014.11.689}, pages = {1314 -- 1317}, year = {2014}, abstract = {A semiconductor field-effect device has been used for an enzymatically catalyzed degradation of biopolymers for the first time. This novel technique is capable to monitor the degradation process of multiple samples in situ and in real-time. As model system, the degradation of the biopolymer poly(D, L-lactic acid) has been monitored in the degradation medium containing the enzyme lipase from Rhizomucor miehei. The obtained results demonstrate the potential of capacitive field-effect sensors for degradation studies of biodegradable polymers.}, language = {en} } @article{HuckPoghossianBaeckeretal.2014, author = {Huck, Christina and Poghossian, Arshak and B{\"a}cker, Matthias and Reisert, Steffen and Schubert, J. and Zander, W. and Begoyan, V. K. and Buniatyan, V. V. and Sch{\"o}ning, Michael Josef}, title = {Chemical sensors based on a high-k perovskite oxide of barium strontium titanate}, series = {Procedia Engineering}, volume = {87}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2014.11.258}, pages = {28 -- 31}, year = {2014}, abstract = {High-k perovskite oxide of barium strontium titanate (BST) represents a very attractive multi-functional transducer material for the development of (bio-)chemical sensors for liquids. In this work, BST films have been applied as a sensitive transducer material for a label-free detection of adsorbed charged macromolecules (positively charged polyelectrolytes) and concentration of hydrogen peroxide vapor as well as protection insulator layer for a contactless electrolyte-conductivity sensor. The experimental results of characterization of individual sensors are presented. Special emphasis is devoted towards the development of a capacitively-coupled contactless electrolyte-conductivity sensor.}, language = {en} } @article{BronderWuPoghossianetal.2014, author = {Bronder, Thomas and Wu, Chunsheng and Poghossian, Arshak and Werner, Frederik and Keusgen, M. and Sch{\"o}ning, Michael Josef}, title = {Label-free detection of DNA hybridization with light-addressable potentiometric sensors: comparison of various DNA-immobilization strategies}, series = {Procedia Engineering}, volume = {87}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2014.11.647}, pages = {755 -- 758}, year = {2014}, abstract = {Light-addressable potentiometric sensors (LAPS) consisting of a p-Si-SiO2 and p-Si-SiO2-Au structure, respectively, have been tested for a label-free electrical detection of DNA (deoxyribonucleic acid) hybridization. Three different strategies for immobilizing single-stranded probe DNA (ssDNA) molecules on a LAPS surface have been studied and compared: (a) immobilization of thiol-modified ssDNA on the patterned Au surface via gold-thiol bond, (b) covalent immobilization of amino-modified ssDNA onto the SiO2 surface functionalized with 3-aminopropyltriethoxysilane and (c) layer-by-layer adsorption of negatively charged ssDNA on a positively charged weak polyelectrolyte layer of poly(allylamine hydrochloride).}, language = {en} } @article{MiyamotoSekiWagneretal.2014, author = {Miyamoto, K. and Seki, K. and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Yoshinobu, T.}, title = {Enhancement of the spatial resolution of the chemical imaging sensor by a hybrid fiber-optic illumination}, series = {Procedia Engineering}, volume = {87}, journal = {Procedia Engineering}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2014.11.563}, pages = {612 -- 615}, year = {2014}, abstract = {The chemical imaging sensor, which is based on the principle of the light-addressable potentiometric sensor (LAPS), is a powerful tool to visualize the spatial distribution of chemical species on the sensor surface. The spatial resolution of this sensor depends on the diffusion of photocarriers excited by a modulated light. In this study, a novel hybrid fiber-optic illumination was developed to enhance the spatial resolution. It consists of a modulated light probe to generate a photocurrent signal and a ring of constant light, which suppresses the lateral diffusion of minority carriers excited by the modulated light. It is demonstrated that the spatial resolution was improved from 92 μm to 68 μm.}, language = {en} } @inproceedings{KernBraun2014, author = {Kern, Alexander and Braun, Christian}, title = {Risk management according to IEC 62305-2 edition 2: 2010-12 assessment of structures with a risk of explosion}, series = {2014 International Conference on Lightning Protection (ICLP), Shanghai, China}, booktitle = {2014 International Conference on Lightning Protection (ICLP), Shanghai, China}, organization = {International Conference on Lightning Protection <2014, Shanghai>}, pages = {1237 -- 1242}, year = {2014}, abstract = {Risk management for structures with a risk of explosion should be considered very carefully when performing a risk analysis according to IEC 62305-2. In contrast to the 2006 edition of the standard, the 2010 edition describes the topic "Structures with a risk of explosion" in more detail. Moreover, in Germany separate procedures and parameters are defined for the risk analysis of structures with a risk of explosion (Supplement 3 of the German DIN EN 62305-2 standard). This paper describes the contents and the relevant calculations of this Supplement 3, together with a numerical example.}, language = {en} } @inproceedings{RousseauKern2014, author = {Rousseau, Alain and Kern, Alexander}, title = {How to deal with environmental risk in IEC 62305-2}, series = {2014 International Conference on Lightning Protection (ICLP), Shanghai, China}, booktitle = {2014 International Conference on Lightning Protection (ICLP), Shanghai, China}, organization = {International Conference on Lightning Protection <2014, Shanghai>}, pages = {521 -- 527}, year = {2014}, abstract = {The 2nd edition of the lightning risk management standard (IEC 62305-2) considers structures, which may endanger environment. In these cases, the loss is not limited to the structure itself, which is valid for usual structures. In the past (Edition 1) this danger was simply taken into account by a special hazard factor, multiplying the existing risk for the structure with a number. Now, in the edition 2, we add to the risk for the structure itself a "second risk" due to the losses outside the structure. The losses outside can be treated independently from what occurs inside. This is a major advantage to analyze the risk for sensitive structures, like chemical plants, nuclear plants, or structures containing explosives, etc. In this paper, the existing procedure given by the European version EN 62305-2 Ed.2 is further developed and applied to a few structures.}, language = {en} } @article{DachwaldMikuckiTulaczyketal.2014, author = {Dachwald, Bernd and Mikucki, Jill and Tulaczyk, Slawek and Digel, Ilya and Espe, Clemens and Feldmann, Marco and Francke, Gero and Kowalski, Julia and Xu, Changsheng}, title = {IceMole : A maneuverable probe for clean in situ analysis and sampling of subsurface ice and subglacial aquatic ecosystems}, series = {Annals of Glaciology}, volume = {55}, journal = {Annals of Glaciology}, number = {65}, publisher = {Cambridge University Press}, address = {Cambridge}, issn = {1727-5644}, doi = {10.3189/2014AoG65A004}, pages = {14 -- 22}, year = {2014}, abstract = {There is significant interest in sampling subglacial environments for geobiological studies, but they are difficult to access. Existing ice-drilling technologies make it cumbersome to maintain microbiologically clean access for sample acquisition and environmental stewardship of potentially fragile subglacial aquatic ecosystems. The IceMole is a maneuverable subsurface ice probe for clean in situ analysis and sampling of glacial ice and subglacial materials. The design is based on the novel concept of combining melting and mechanical propulsion. It can change melting direction by differential heating of the melting head and optional side-wall heaters. The first two prototypes were successfully tested between 2010 and 2012 on glaciers in Switzerland and Iceland. They demonstrated downward, horizontal and upward melting, as well as curve driving and dirt layer penetration. A more advanced probe is currently under development as part of the Enceladus Explorer (EnEx) project. It offers systems for obstacle avoidance, target detection, and navigation in ice. For the EnEx-IceMole, we will pay particular attention to clean protocols for the sampling of subglacial materials for biogeochemical analysis. We plan to use this probe for clean access into a unique subglacial aquatic environment at Blood Falls, Antarctica, with return of a subglacial brine sample.}, language = {en} } @article{Stulpe2014, author = {Stulpe, Werner}, title = {From the attempt of certain classical reformulations of quantum mechanics to quasi-probability representations}, series = {Journal of Mathematical Physics}, volume = {55}, journal = {Journal of Mathematical Physics}, number = {1}, publisher = {AIP Publishing}, address = {College Park, Md.}, issn = {222-488}, doi = {10.1063/1.4861939}, pages = {Artikel 012109}, year = {2014}, abstract = {The concept of an injective affine embedding of the quantum states into a set of classical states, i.e., into the set of the probability measures on some measurable space, as well as its relation to statistically complete observables is revisited, and its limitation in view of a classical reformulation of the statistical scheme of quantum mechanics is discussed. In particular, on the basis of a theorem concerning a non-denseness property of a set of coexistent effects, it is shown that an injective classical embedding of the quantum states cannot be supplemented by an at least approximate classical description of the quantum mechanical effects. As an alternative approach, the concept of quasi-probability representations of quantum mechanics is considered.}, language = {en} } @article{LevesqueSiegwolfEilmannetal.2014, author = {L{\´e}vesque, Mathieu and Siegwolf, Rolf and Eilmann, Britta and Saurer, Matthias and Rigling, Andreas}, title = {Increased water-use efficiency does not lead to enhanced tree growth under xeric and mesic conditions}, series = {New Phytologist}, volume = {203}, journal = {New Phytologist}, number = {1}, publisher = {Wiley-Blackwell}, address = {Oxford}, issn = {1469-8137 (Online)}, doi = {10.1111/nph.12772}, pages = {94 -- 109}, year = {2014}, language = {en} } @article{EilmannSterckWegneretal.2014, author = {Eilmann, Britta and Sterck, Frank J. and Wegner, L. and de Vries, Sven M. G. and von Arx, G. and Mohren, Godefridus M. J. and den Ouden, Jan and Sass-Klaassen, Ute G. W.}, title = {Wood structural differences between northern and southern beech provenances growing at a moderate site}, series = {Tree Physiology}, volume = {34}, journal = {Tree Physiology}, number = {8}, publisher = {Oxford University Press}, address = {Oxford}, issn = {1758-4469 (Online)}, doi = {10.1093/treephys/tpu069}, pages = {882 -- 893}, year = {2014}, language = {en} } @article{FeichtingerEilmannBuchmannetal.2014, author = {Feichtinger, Linda M. and Eilmann, Britta and Buchmann, Nina and Rigling, Andreas}, title = {Growth adjustments of conifers to drought and to century-long irrigation}, series = {Forest Ecology and Management}, volume = {2014}, journal = {Forest Ecology and Management}, number = {334}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1872-7042 (Online)}, doi = {10.1016/j.foreco.2014.08.008}, pages = {96 -- 105}, year = {2014}, abstract = {Our knowledge on tree responses to drought is mainly based on short-term manipulation experiments which do not capture any possible long-term adjustments in this response. Therefore, historical water channels in inner-Alpine dry valleys were used as century-long irrigation experiments to investigate adjustments in tree growth to contrasting water supply. This involved quantifying the tree-ring growth of irrigated and non-irrigated (control) Scots pine (Pinus sylvestris L.) in Valais (Switzerland), as well as European larch (Larix decidua Mill.) and black pine (Pinus nigra Arnold) in Vinschgau (Italy). Furthermore, the adjustments in radial growth of Scots pine and European larch to an abrupt stop in irrigation were analyzed. Irrigation promoted the radial growth of all tree species investigated compared to the control: (1) directly through increased soil water availability, and (2) indirectly through increased soil nutrients and humus contents in the irrigated plots. Irrigation led to a full elimination of growth responses to climate for European larch and black pine, but not for Scots pine, which might become more sensitive to drought with increasing tree size in Valais. For the control trees, the response of the latewood increment to water availability in July/August has decreased in recent decades for all species, but increased in May for Scots pine only. The sudden irrigation stop caused a drop in radial growth to a lower level for Scots pine or similar level for larch compared to the control for up to ten years. However, both tree species were then able to adjust to the new conditions and subsequently grew with similar (Scots pine) or even higher growth rates (larch) than the control. To estimate the impact of climate change on future forest development, the duration of manipulation experiments should be on longer time scales in order to capture adjustment processes and feedback mechanisms of forest ecosystems.}, language = {en} } @inproceedings{Bung2014, author = {Bung, Daniel B.}, title = {Observations on non-aerated flow and air entrainment on moderately sloped stepped spillways}, series = {7th Chinese-German Joint Symposium on Hydraulic and Ocean Engineering : 8. - 12. Sept. 2014, Hannover}, booktitle = {7th Chinese-German Joint Symposium on Hydraulic and Ocean Engineering : 8. - 12. Sept. 2014, Hannover}, organization = {Chinese-German Joint Symposium on Hydraulic and Ocean Engineering <7, 2014, Hannover>}, pages = {1 -- 8}, year = {2014}, language = {en} } @inproceedings{BungOertel2014, author = {Bung, Daniel B. and Oertel, Mario}, title = {Manipulation of non-aerated cavity flow on a stepped spillway model}, series = {3rd European IAHR Congress : April 14 - 16, 2014, Porto}, booktitle = {3rd European IAHR Congress : April 14 - 16, 2014, Porto}, publisher = {Univ. of Porto}, address = {Porto}, organization = {International Association of Hydro-Environment Engineering and Research}, year = {2014}, language = {en} } @article{LeandroBungCarvalho2014, author = {Leandro, J. and Bung, Daniel B. and Carvalho, R.}, title = {Measuring void fraction and velocity fields of a stepped spillway for skimming flow using non-intrusive methods}, series = {Experiments in fluids}, journal = {Experiments in fluids}, number = {55}, publisher = {Springer Nature}, address = {Heidelberg}, issn = {0723-4864 (Print) ; 1432-1114 (Online)}, doi = {10.1007/s00348-014-1732-6}, pages = {Art. 1732}, year = {2014}, language = {en} } @article{RatkeMilowLisinskietal.2014, author = {Ratke, Lorenz and Milow, Barbara and Lisinski, Susanne and Hoepfner, Sandra}, title = {On an effect of fine ceramic particles on the structure of aerogels}, series = {Microgravity science and technology}, volume = {26}, journal = {Microgravity science and technology}, publisher = {Springer Nature}, address = {Heidelberg}, issn = {0938-0108 ; 1875-0494}, doi = {10.1007/s12217-014-9380-2}, pages = {103 -- 110}, year = {2014}, language = {en} } @article{AlmajhdiSengerAmeretal.2014, author = {Almajhdi, Fahad N. and Senger, Tilo and Amer, Haitham M. and Gissmann, Lutz and {\"O}hlschl{\"a}ger, Peter}, title = {Design of a highly effective therapeutic HPV16 E6/E7-specific DNA vaccine: optimization by different ways of sequence rearrangements (Shuffling)}, series = {PLOS one}, volume = {11}, journal = {PLOS one}, number = {9}, publisher = {PLOS}, address = {San Francisco}, issn = {1932-6203}, doi = {10.1371/journal.pone.0113461}, pages = {e113461}, year = {2014}, abstract = {Persistent infection with the high-risk Human Papillomavirus type 16 (HPV 16) is the causative event for the development of cervical cancer and other malignant tumors of the anogenital tract and of the head and neck. Despite many attempts to develop therapeutic vaccines no candidate has entered late clinical trials. An interesting approach is a DNA based vaccine encompassing the nucleotide sequence of the E6 and E7 viral oncoproteins. Because both proteins are consistently expressed in HPV infected cells they represent excellent targets for immune therapy. Here we report the development of 8 DNA vaccine candidates consisting of differently rearranged HPV-16 E6 and E7 sequences within one molecule providing all naturally occurring epitopes but supposedly lacking transforming activity. The HPV sequences were fused to the J-domain and the SV40 enhancer in order to increase immune responses. We demonstrate that one out of the 8 vaccine candidates induces very strong cellular E6- and E7- specific cellular immune responses in mice and, as shown in regression experiments, efficiently controls growth of HPV 16 positive syngeneic tumors. This data demonstrates the potential of this vaccine candidate to control persistent HPV 16 infection that may lead to malignant disease. It also suggests that different sequence rearrangements influence the immunogenecity by an as yet unknown mechanism.}, language = {en} } @misc{ReyesOchoa2014, type = {Master Thesis}, author = {Reyes Ochoa, Leonel}, title = {Engineering aspects of a parabolic trough collector field with direct steam generation and an organic rankine cycle}, publisher = {Fachhochschule Aachen}, address = {Aachen}, pages = {X, 72 S.}, year = {2014}, language = {en} } @inproceedings{VoronkovaBauerKotliar2014, author = {Voronkova, Eva B. and Bauer, Svetlana M. and Kotliar, Konstantin}, title = {Computer simulation of the cornea-scleral shell as applied to pressure-volume relationship in the human eye}, series = {2014 International Conference on Computer Technologies in Physical and Engineering Applications : ICCTPEA 2014 : proceedings : June 30 2014-July 4 2014, St. Petersburg}, booktitle = {2014 International Conference on Computer Technologies in Physical and Engineering Applications : ICCTPEA 2014 : proceedings : June 30 2014-July 4 2014, St. Petersburg}, organization = {Institute of Electrical and Electronics Engineers}, isbn = {978-1-4799-5315-8}, pages = {204 -- 205}, year = {2014}, language = {en} } @inproceedings{BaeckerSchusserLeinhosetal.2014, author = {B{\"a}cker, Matthias and Schusser, Sebastian and Leinhos, Marcel and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Sensor system for the monitoring of degradation processes of biodegradable biopolymers}, series = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)}, booktitle = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)}, publisher = {VDE-Verl.}, address = {D{\"u}sseldorf}, organization = {VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik}, isbn = {978-3-8007-3622-5}, pages = {1 -- 4}, year = {2014}, language = {en} }