@article{Olbertz2012, author = {Olbertz, Klaus}, title = {{\"U}bergang von Leiharbeitnehmern bei {\"U}bertragung des Entleiherbetriebs - Entscheidung des EuGH zum Recht des Betriebs{\"u}bergangs}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {5}, publisher = {NWB-Verlag}, address = {Herne}, issn = {1860-9449}, pages = {398 -- 403}, year = {2012}, abstract = {Wieder einmal hat eine Entscheidung des Europ{\"a}ischen Gerichtshofs (EuGH) das bisherige nationale Verst{\"a}ndnis zu einer Frage des Rechts des Betriebs{\"u}bergangs erheblich ins Wanken gebracht. Bisher entsprach es allgemeiner Auffassung, dass die Arbeitsverh{\"a}ltnisse von Zeit- bzw. Leiharbeitnehmern bei einem Betriebs(teil){\"u}bergang des die Leiharbeitnehmer entleihenden Betriebs nicht auf den Betriebserwerber {\"u}bergehen. Der EuGH hat in der Rechtssache Albron Catering mit Urteil vom 21.10.2010 jedoch entschieden, dass auch Leiharbeitnehmer von einem Betriebs(teil){\"u}bergang erfasst sein k{\"o}nnen. Folglich kann der Erwerber eines Betriebs oder Betriebsteils gem. \S 613a BGB zuk{\"u}nftig verpflichtet sein, auch die an den Betriebsver{\"a}ußerer verliehenen Leiharbeitnehmer zu {\"u}bernehmen. Die Entscheidung des EuGH hat somit zur Konsequenz, dass der {\"U}bergang von Leiharbeitsverh{\"a}ltnissen auf den Erwerber eines Betriebs jedenfalls nicht mehr pauschal ausgeschlossen werden kann. Dies gilt es bei k{\"u}nftigen Betriebs(teil){\"u}bertragungen zu ber{\"u}cksichtigen, um unliebsame {\"U}berraschungen zu vermeiden.}, language = {de} } @article{Lind2012, author = {Lind, Thorsten Patric}, title = {Zur Rechtsscheinhaftung bei Handeln einer Unternehmergesellschaft unter dem Rechtsformzusatz „GmbH" : Urteil vom 12.06.2012 - II ZR 256/11 : Anmerkung}, series = {Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-M{\"o}hring}, journal = {Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-M{\"o}hring}, number = {Ausg. 11}, publisher = {Beck}, address = {M{\"u}nchen}, issn = {1611-1095}, pages = {339268}, year = {2012}, language = {de} } @article{RiglingElkinDobbertinetal.2012, author = {Rigling, Andreas and Elkin, Ch{\´e} and Dobbertin, Matthias and Eilmann, Britta and Giuggiola, Arnaud and Wohlgemuth, Thomas and Bugmann, Harald}, title = {Wald und Klimawandel in der inneralpinen Trockenregion Visp}, series = {Schweizerische Zeitschrift f{\"u}r Forstwesen}, volume = {163}, journal = {Schweizerische Zeitschrift f{\"u}r Forstwesen}, number = {12}, publisher = {Schweizerischer Forstverein}, address = {Z{\"u}rich}, issn = {2235-1469 (Online)}, doi = {10.3188/szf.2012.0481}, pages = {481 -- 492}, year = {2012}, abstract = {Der Temperaturanstieg der vergangenen Jahrzehnte war in Gebirgsregionen besonders ausgepr{\"a}gt. Sollte sich dieser Temperaturtrend im 21. Jahrhundert fortsetzen, dann d{\"u}rf-ten sich auch die H{\"a}ufigkeit und Intensit{\"a}t von Niederschl{\"a}-gen und Trockenperioden ver{\"a}ndern, was die Waldwirtschaft vor grosse Herausforderungen stellen wird. Trockenheit ist ein entscheidender Faktor f{\"u}r die Wald{\"o}kosysteme der inner-alpinen T{\"a}ler, wo seit Jahren trockenheitsbedingtes Baum-sterben festgestellt wird. Der vorliegende Beitrag hat zum Ziel, die Sensitivit{\"a}t der verschiedenen Wald{\"o}kosysteme ge-gen{\"u}ber Klimawandel und alternative, teilweise extreme Bewirtschaftungsvarianten in der Region Visp zu testen. Me-thodische Ans{\"a}tze wie Monitoring, Feldexperimente und dy-namische Modellierung wurden kombiniert, und es wurden verschiedene {\"O}kosystemleistungen ber{\"u}cksichtigt, so Holz-produktion, Schutz vor Naturgefahren, Kohlenstoffspeiche-rung und Aspekte der Biodiversit{\"a}t. Die Resultate deuten da-rauf hin, dass auf den Trockenstandorten der Tieflagen die einheimischen Baumarten an ihre physiologischen Grenzen stossen und l{\"a}ngerfristig {\"u}ber alternative Baumarten nach-gedacht werden sollte. In den mittleren Lagen d{\"u}rften Tro-ckenheit und Schadinsekten wie die Borkenk{\"a}fer die zuk{\"u}nf-tige Waldentwicklung steuern. In den Hochlagen hingegen werden sich die W{\"a}lder ausdehnen und besser wachsen als heute. Alle untersuchten {\"O}kosystemleistungen werden ge-bietsweise starken Ver{\"a}nderungen unterworfen sein. Die dis-kutierten Bewirtschaftungsvarianten scheinen dazu geeignet, die Wasserverf{\"u}gbarkeit der Best{\"a}nde, haupts{\"a}chlich in tief-eren Lagen, zu erh{\"o}hen und dadurch die Widerstandskraft der B{\"a}ume gegen{\"u}ber Trockenperioden vor{\"u}bergehend zu st{\"a}rken. Es ist aber davon ausgehen, dass nur verh{\"a}ltnism{\"a}s-sig starke Eingriffe wesentliche Effekte erzielen k{\"o}nnen. Die Verkn{\"u}pfung von Umweltmonitoring, Feldexperimenten und Modellierung unter Miteinbezug von {\"O}kosystemleistungen ist vielversprechend, da sie eine differenzierte Absch{\"a}tzung des zuk{\"u}nftigen Landschaftswandels und seiner Effekte auf die Waldleistungen erm{\"o}glicht.}, language = {de} } @article{Wolf2012, author = {Wolf, Martin}, title = {Von Security Awareness zum Secure Behaviour}, series = {Hakin9 Extra - IT-Forensik}, volume = {2012}, journal = {Hakin9 Extra - IT-Forensik}, number = {5}, publisher = {Software Wydawnictwo}, address = {Warszawa}, issn = {1733-7186}, pages = {18 -- 19}, year = {2012}, abstract = {Security Awareness ist derzeit ein viel diskutiertes Thema. Es reicht nicht, einfach nur ein paar technische Systeme (z.B. Firewalls) zu installieren, um ein angemessenes Schutzniveau zu erzielen. Neben einer guten Organisation von IT Security ist es auch notwendig, den Mitarbeiter einzubinden. Der vielzitierte "Faktor Mensch" ist derjenige, der die Technik korrekt anwenden muss und der durch falsches Verhalten technische und organisatorische Schutzmaßnahmen aushebeln kann. Deshalb reicht es nicht aus, wenn sich der Mitarbeiter der Gefahren bewusst ("aware") ist, er muss auch dementsprechend "sicher" handeln.}, language = {de} } @article{Lind2012, author = {Lind, Thorsten Patric}, title = {Vollzug der Schenkung einer Unterbeteiligung : BGH, Urteil vom 29.11.2011 - II ZR 306/09 : Anmerkung}, series = {Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-M{\"o}hring}, journal = {Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-M{\"o}hring}, number = {Ausg. 4}, publisher = {Beck}, address = {M{\"u}nchen}, issn = {1611-1095}, pages = {330150}, year = {2012}, language = {de} } @article{FissabreLohmann2012, author = {Fissabre, Anke and Lohmann, Daniel}, title = {Verlust einer „tragenden Wand" : Das Haus der Jugend von Rudolf Schwarz in Aachen}, series = {Bauwelt}, volume = {103}, journal = {Bauwelt}, number = {45}, publisher = {Bauverlag BV}, address = {G{\"u}tersloh}, issn = {0005-6855}, pages = {6 -- 7}, year = {2012}, language = {de} } @article{Frings2012, author = {Frings, Michael}, title = {Verbesserter Schutz vor Kostenfallen im elektronischen Gesch{\"a}ftsverkehr („Buttonl{\"o}sung") : Erster Schritt zur Umsetzung der neuen EU-Verbraucherrechterichtlinie}, series = {NWB : NWB-Steuer- und Wirtschaftsrecht}, volume = {2012}, journal = {NWB : NWB-Steuer- und Wirtschaftsrecht}, number = {23}, publisher = {NWB-Verlag}, address = {Herne}, issn = {0028-3460}, pages = {1912 -- 1918}, year = {2012}, abstract = {Der Deutsche Bundestag und Bundesrat haben am 2.3.2012 bzw. 30.3.2012 das Gesetz gegen Kostenfallen im Internet verabschiedet, das am 1.8.2012 in Kraft treten wird. Hiermit hat der deutsche Gesetzgeber einen ersten Schritt getan, um die neue EU-Verbraucherrechterichtlinie vom 25.10.2011 (2011/83/EU, ABl L 304/64) in nationales Recht umzusetzen. Mit dieser Umsetzung ist das dr{\"a}ngendste Problem der Kosten- und Abo-Fallen im elektronischen Gesch{\"a}ftsverkehr aus dem Gesamtpaket der Verbraucherrechterichtlinie herausgel{\"o}st und in dem neugefassten \S 312g BGB behandelt worden. Eile bei der Umsetzung war hier geboten, weil unseri{\"o}se Unternehmen im elektronischen Rechtsverkehr zunehmend und in großem Umfang gegen{\"u}ber ihren Kunden durch irref{\"u}hrende Gestaltungen ihrer Internetseiten verschleiern, dass die angebotenen Leistungen entgeltpflichtig sind.}, language = {de} } @article{YazdanbakhshSolbachBitz2012, author = {Yazdanbakhsh, Pedram and Solbach, Klaus and Bitz, Andreas}, title = {Variable power combiner for RF mode shimming in 7-T MR imaging}, series = {IEEE Transaction on Biomedical Engineering}, volume = {59}, journal = {IEEE Transaction on Biomedical Engineering}, number = {9}, publisher = {IEEE}, address = {New York}, issn = {1558-2531}, doi = {10.1109/TBME.2012.2205926}, pages = {2549 -- 2557}, year = {2012}, abstract = {This contribution discusses the utilization of RF power in an MRI system with RF mode shimming which enables the superposition of circularly polarized modes of a transmit RF coil array driven by a Butler matrix. Since the required power for the individual modes can vary widely, mode-shimming can result in a significant underutilization of the total available RF power. A variable power combiner (VPC) is proposed to improve the power utilization: it can be realized as a reconfiguration of the MRI transmit system by the inclusion of one additional matrix network which receives the power from all transmit amplifiers at its input ports and provides any desired (combined) power distribution at its output ports by controlling the phase and amplitude of the amplifiers' input signals. The power distribution at the output ports of the VPC is then fed into the "mode" ports of the coil array Butler matrix in order to superimpose the spatial modes at the highest achievable power utilization. The VPC configuration is compared to the standard configuration of the transmit chain of our MRI system with 8 transmit channels and 16 coils. In realistic scenarios, improved power utilization was achieved from 17\% to 60\% and from 14\% to 55\% for an elliptical phantom and a region of interest in the abdomen, respectively, and an increase of the power utilization of 1 dB for a region of interest in the upper leg. In general, it is found that the VPC allows significant improvement in power utilization when the shimming solution demands only a few modes to be energized, while the technique can yield loss in power utilization in cases with many modes required at high power level.}, language = {en} } @article{Huening2012, author = {H{\"u}ning, Felix}, title = {Using Trench PowerMOSFETs in Linear Mode}, series = {Power Electronics Europe (2012)}, journal = {Power Electronics Europe (2012)}, publisher = {DFA Media}, address = {Tonbridge}, issn = {1748-3530}, pages = {27 -- 29}, year = {2012}, abstract = {If we think about applications for modern Power MOSFETs using trench technology, running them in linear mode may not be top of the priority list. Yet there are multiple uses for Trench Power MOSFETs in linear mode. In fact, even turning the device on and off in switching applications is a form of linear operation. Also, these components can be run in linear mode to protect the device against voltage surges. This article will illustrate the factors that need to be considered for linear operation and show how Trench Power MOSFETs are suited to it.}, language = {en} } @article{PaulssenNgyugenKahlckeetal.2012, author = {Paulßen, Elisabeth and Ngyugen, Hung Huy and Kahlcke, Nils and Deflon, Victor M. and Abram, Ulrich}, title = {Tricarbonyltechnetium(I) and -rhenium(I) complexes with N′-thiocarbamoylpicolylbenzamidines}, series = {Polyhedron}, volume = {40}, journal = {Polyhedron}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0277-5387}, doi = {10.1016/j.poly.2012.04.008}, pages = {153 -- 158}, year = {2012}, abstract = {N,N-Dialkylamino(thiocarbonyl)-N′-picolylbenzamidines react with (NEt4)2[M(CO)3X3] (M = Re, X = Br; M = Tc, X = Cl) under formation of neutral [M(CO)3L] complexes in high yields. The monoanionic NNS ligands bind in a facial coordination mode and can readily be modified at the (CS)NR1R2 moiety. The complexes [99Tc(CO)3(LPyMor)] and [Re(CO)3(L)] (L = LPyMor, LPyEt) were characterized by X-ray diffraction. Reactions of [99mTc(CO)3(H2O)3]+ with the N′-thiocarbamoylpicolylbenzamidines give the corresponding 99mTc complexes. The ester group in HLPyCOOEt allows linkage between biomolecules and the metal core.}, language = {en} } @article{EilmannRigling2012, author = {Eilmann, Britta and Rigling, Andreas}, title = {Tree-growth analyses to estimate tree species' drought tolerance}, series = {Tree Physiology}, volume = {32}, journal = {Tree Physiology}, number = {2}, editor = {Abrams, Marc}, publisher = {Oxford University Press}, address = {Oxford}, issn = {0829-318X (Print)}, doi = {10.1093/treephys/tps004}, pages = {178 -- 187}, year = {2012}, abstract = {Climate change is challenging forestry management and practices. Among other things, tree species with the ability to cope with more extreme climate conditions have to be identified. However, while environmental factors may severely limit tree growth or even cause tree death, assessing a tree species' potential for surviving future aggravated environmental conditions is rather demanding. The aim of this study was to find a tree-ring-based method suitable for identifying very drought-tolerant species, particularly potential substitute species for Scots pine (Pinus sylvestris L.) in Valais. In this inner-Alpine valley, Scots pine used to be the dominating species for dry forests, but today it suffers from high drought-induced mortality. We investigate the growth response of two native tree species, Scots pine and European larch (Larix decidua Mill.), and two non-native species, black pine (Pinus nigra Arnold) and Douglas fir (Pseudotsuga menziesii Mirb. var. menziesii), to drought. This involved analysing how the radial increment of these species responded to increasing water shortage (abandonment of irrigation) and to increasingly frequent drought years. Black pine and Douglas fir are able to cope with drought better than Scots pine and larch, as they show relatively high radial growth even after irrigation has been stopped and a plastic growth response to drought years. European larch does not seem to be able to cope with these dry conditions as it lacks the ability to recover from drought years. The analysis of trees' short-term response to extreme climate events seems to be the most promising and suitable method for detecting how tolerant a tree species is towards drought. However, combining all the methods used in this study provides a complete picture of how water shortage could limit species.}, language = {en} } @article{FischerKowalskiPudasaini2012, author = {Fischer, Jan-Thomas and Kowalski, Julia and Pudasaini, Shiva P.}, title = {Topographic curvature effects in applied avalanche modelling}, series = {Cold Regions Science and Technology}, volume = {74-75}, journal = {Cold Regions Science and Technology}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1872-7441}, doi = {10.1016/j.coldregions.2012.01.005}, pages = {21 -- 30}, year = {2012}, abstract = {This paper describes the implementation of topographic curvature effects within the RApid Mass MovementS (RAMMS) snow avalanche simulation toolbox. RAMMS is based on a model similar to shallow water equations with a Coulomb friction relation and the velocity dependent Voellmy drag. It is used for snow avalanche risk assessment in Switzerland. The snow avalanche simulation relies on back calculation of observed avalanches. The calibration of the friction parameters depends on characteristics of the avalanche track. The topographic curvature terms are not yet included in the above mentioned classical model. Here, we fundamentally improve this model by mathematically and physically including the topographic curvature effects. By decomposing the velocity dependent friction into a topography dependent term that accounts for a curvature enhancement in the Coulomb friction, and a topography independent contribution similar to the classical Voellmy drag, we construct a general curvature dependent frictional resistance, and thus propose new extended model equations. With three site-specific examples, we compare the apparent frictional resistance of the new approach, which includes topographic curvature effects, to the classical one. Our simulation results demonstrate substantial effects of the curvature on the flow dynamics e.g., the dynamic pressure distribution along the slope. The comparison of resistance coefficients between the two models demonstrates that the physically based extension presents an improvement to the classical approach. Furthermore a practical example highlights its influence on the pressure outline in the run out zone of the avalanche. Snow avalanche dynamics modeling natural terrain curvature centrifugal force friction coefficients.}, language = {en} } @article{OrzadaMaderwaldPoseretal.2012, author = {Orzada, S. and Maderwald, S. and Poser, B. A. and Johst, S. and Kannengiesser, S. and Ladd, M. E. and Bitz, Andreas}, title = {Time-interleaved acquisition of modes: an analysis of SAR and image contrast implications}, series = {Magnetic Resonance in Medicine}, volume = {67}, journal = {Magnetic Resonance in Medicine}, number = {4}, publisher = {Wiley-Liss}, address = {New York}, issn = {1522-2594}, doi = {10.1002/mrm.23081}, pages = {1033 -- 1041}, year = {2012}, abstract = {s the magnetic field strength and therefore the operational frequency in MRI are increased, the radiofrequency wavelength approaches the size of the human head/body, resulting in wave effects which cause signal decreases and dropouts. Especially, whole-body imaging at 7 T and higher is therefore challenging. Recently, an acquisition scheme called time-interleaved acquisition of modes has been proposed to tackle the inhomogeneity problems in high-field MRI. The basic premise is to excite two (or more) different Burn:x-wiley:07403194:media:MRM23081:tex2gif-stack-1 modes using static radiofrequency shimming in an interleaved acquisition, where the complementary radiofrequency patterns of the two modes can be exploited to improve overall signal homogeneity. In this work, the impact of time-interleaved acquisition of mode on image contrast as well as on time-averaged specific absorption rate is addressed in detail. Time-interleaved acquisition of mode is superior in Burn:x-wiley:07403194:media:MRM23081:tex2gif-stack-2 homogeneity compared with conventional radiofrequency shimming while being highly specific absorption rate efficient. Time-interleaved acquisition of modes can enable almost homogeneous high-field imaging throughout the entire field of view in PD, T2, and T2*-weighted imaging and, if a specified homogeneity criterion is met, in T1-weighted imaging as well.}, language = {en} } @article{ScheikSchleserReisgen2012, author = {Scheik, Sven and Schleser, Markus and Reisgen, Uwe}, title = {Thermisches Direktf{\"u}gen von Metall und Kusntstoff: eine Alternative zur Klebtechnik}, series = {Adh{\"a}sion : Kleben \& Dichten}, volume = {56}, journal = {Adh{\"a}sion : Kleben \& Dichten}, number = {11}, publisher = {Springer Vieweg}, address = {Wiesbaden}, issn = {0001-8198 (E-Journal); 0001-8198 (Print)}, doi = {10.1007/s35145-012-0005-x}, pages = {36 -- 40}, year = {2012}, abstract = {Im Rahmen des Exzellenzclusters „Integrative Produktionstechnik f{\"u}r Hochlohnl{\"a}nder" der RWTHAachen University werden derzeit alternative Verfahren zur Herstellung von Metall/Kunststoff- Verbindungen untersucht. Eines davon ist das thermische Direktf{\"u}gen, das eine stoffschl{\"u}ssige Verbindung zwischen Kunststoff und Metall erm{\"o}glicht und ohne die Verwendung von Klebstoffen, Haftvermittlern oder mechanischen Verbindungshilfen auskommt.}, language = {de} } @article{StadlerGarveyBocahutetal.2012, author = {Stadler, Andreas M. and Garvey, G. J. and Bocahut, A. and Sacquin-Mora, S. and Digel, Ilya and Schneider, G. J. and Natali, F. and Artmann, Gerhard and Zaccai, G.}, title = {Thermal fluctuations of haemoglobin from different species : adaptation to temperature via conformational dynamics}, series = {Journal of the Royal Society Interface}, volume = {9}, journal = {Journal of the Royal Society Interface}, number = {76}, publisher = {The Royal Society}, address = {London}, issn = {1742-5689}, doi = {10.1098/rsif.2012.0364}, pages = {2845 -- 2855}, year = {2012}, abstract = {Thermodynamic stability, configurational motions and internal forces of haemoglobin (Hb) of three endotherms (platypus, Ornithorhynchus anatinus; domestic chicken, Gallus gallus domesticus and human, Homo sapiens) and an ectotherm (salt water crocodile, Crocodylus porosus) were investigated using circular dichroism, incoherent elastic neutron scattering and coarse-grained Brownian dynamics simulations. The experimental results from Hb solutions revealed a direct correlation between protein resilience, melting temperature and average body temperature of the different species on the 0.1 ns time scale. Molecular forces appeared to be adapted to permit conformational fluctuations with a root mean square displacement close to 1.2 {\AA} at the corresponding average body temperature of the endotherms. Strong forces within crocodile Hb maintain the amplitudes of motion within a narrow limit over the entire temperature range in which the animal lives. In fully hydrated powder samples of human and chicken, Hb mean square displacements and effective force constants on the 1 ns time scale showed no differences over the whole temperature range from 10 to 300 K, in contrast to the solution case. A complementary result of the study, therefore, is that one hydration layer is not sufficient to activate all conformational fluctuations of Hb in the pico- to nanosecond time scale which might be relevant for biological function. Coarse-grained Brownian dynamics simulations permitted to explore residue-specific effects. They indicated that temperature sensing of human and chicken Hb occurs mainly at residues lining internal cavities in the β-subunits.}, language = {en} } @article{NomdedeuWillenSchiefferetal.2012, author = {Nomdedeu, Mar Monsonis and Willen, Christine and Schieffer, Andre and Arndt, Hartmut}, title = {Temperature-dependent ranges of coexistence in a model of a two-prey-one-predator microbial food web}, series = {Marine Biology}, volume = {159}, journal = {Marine Biology}, number = {11}, publisher = {Springer}, address = {Berlin}, issn = {1432-1793}, doi = {10.1007/s00227-012-1966-x}, pages = {2423 -- 2430}, year = {2012}, abstract = {The objective of our study was to analyze the effects of temperature on the population dynamics of a three-species food web consisting of two prey bacteria (Pedobacter sp. and Acinetobacter johnsonii) and a protozoan predator (Tetrahymena pyriformis) as model organisms. We assessed the effects of temperature on the growth rates of all three species with the objective of developing a model with four differential equations based on the experimental data. The following hypotheses were tested at a theoretical level: Firstly, temperature changes can affect the dynamic behavior of a system by temperature-dependent parameters and interactions and secondly, food web response to temperature cannot be derived from the single species temperature response. The main outcome of the study is that temperature changes affect the parameter range where coexistence is possible within all three species. This has significant consequences on our ideas regarding the evaluation of effects of global warming.}, language = {en} } @article{ImmelGruetzkeSpaeteetal.2012, author = {Immel, Timo and Gr{\"u}tzke, Martin and Sp{\"a}te, Anne-Katrin and Groth, Ulrich and {\"O}hlschl{\"a}ger, Peter and Huhn, Thomas}, title = {Synthesis and X-ray structure analysis of a heptacoordinate titanium(IV)-bis-chelate with enhanced in vivo antitumor efficacy}, series = {Chemical Communications}, volume = {48}, journal = {Chemical Communications}, number = {46}, publisher = {Royal Society of Chemistry}, address = {Cambridge}, issn = {1364-548X}, doi = {10.1039/C2CC31624B}, pages = {5790 -- 5792}, year = {2012}, abstract = {Chelate stabilization of a titanium(IV)-salan alkoxide by ligand exchange with 2,6-pyridinedicarboxylic acid (dipic) resulted in heptacoordinate complex 3 which is not redox-active, stable on silica gel and has increased aqueous stability. 3 is highly toxic in HeLa S3 and Hep G2 and has enhanced antitumor efficacy in a mouse cervical-cancer model.}, language = {en} } @article{Grotendorst2012, author = {Grotendorst, Johannes}, title = {Supercomputer programmieren - ein besonderes Studienangebot in J{\"u}lich}, series = {Junge Wissenschaft. 27 (2012), H. 94}, journal = {Junge Wissenschaft. 27 (2012), H. 94}, publisher = {-}, isbn = {0179-8529}, pages = {12 -- 14}, year = {2012}, language = {de} } @article{Weigand2012, author = {Weigand, Christoph}, title = {Statistical Tests Based on Reliability and Precision}, series = {Economic Quality Control : EQC ; international journal for quality and reliability}, volume = {27}, journal = {Economic Quality Control : EQC ; international journal for quality and reliability}, number = {1}, publisher = {De Gruyter}, address = {Berlin}, issn = {1869-6147}, doi = {10.1515/eqc-2012-0002}, pages = {43 -- 64}, year = {2012}, abstract = {The construction of a statistical test is investigated which is based only on "reliability" and "precision" as quality criteria. The reliability of a statistical test is quantifiedin a straightforward way by the probability that the decision of the test is correct. However, the quantification of the precision of a statistical test is not at all evident. Thereforethe paper presents and discusses several approaches. Moreover the distinction of "nullhypothesis" and "alternative hypothesis" is not necessary any longer.}, language = {en} } @article{ReisgenSchleserMokrovetal.2012, author = {Reisgen, Uwe and Schleser, Markus and Mokrov, Oleg and Ahmed, Essam}, title = {Statistical modeling of laser welding of DP/TRIP steel sheets}, series = {Optics and laser technology}, volume = {44}, journal = {Optics and laser technology}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1879-2545 (E-Journal); 0030-3992 (Print); 0308-4280 (Print)}, doi = {10.1016/j.optlastec.2011.05.025}, pages = {92 -- 101}, year = {2012}, abstract = {In this research work, a statistical analysis of the CO2 laser beam welding of dual phase (DP600)/transformation induced plasticity (TRIP700) steel sheets was done using response surface methodology. The analysis considered the effect of laser power (2-2.2 kW), welding speed (40-50 mm/s) and focus position (-1 to 0 mm) on the heat input, the weld bead geometry, uniaxial tensile strength, formability limited dome height and welding operation cost. The experimental design was based on Box-Behnken design using linear and quadratic polynomial equations for predicting the mathematical models. The results indicate that the proposed models predict the responses adequately within the limits of welding parameters being used and the welding speed is the most significant parameter during the welding process.}, language = {en} } @article{SchubaHoefkenSchaefer2012, author = {Schuba, Marko and H{\"o}fken, H. and Schaefer, T.}, title = {Smartphone Forensik}, series = {Hakin9 : Practical Protection (2012)}, journal = {Hakin9 : Practical Protection (2012)}, publisher = {-}, isbn = {1733-7186}, pages = {10 -- 20}, year = {2012}, language = {de} } @article{HoetterFateriGebhardt2012, author = {H{\"o}tter, Jan-Steffen and Fateri, Miranda and Gebhardt, Andreas}, title = {Selective laser melting of metals: desktop machines open up new chances even for small companies}, series = {Advanced materials research}, volume = {622-623}, journal = {Advanced materials research}, publisher = {Trans Tech Publ.}, address = {Baech}, issn = {1662-8985 (E-Journal); 1022-6680 (Print)}, doi = {10.4028/www.scientific.net/AMR.622-623.461}, pages = {461 -- 465}, year = {2012}, abstract = {Additive manufacturing (AM) of metal parts by using Selective Laser Melting (SLM) has become a powerful tool mostly in the area of automotive, aerospace engineering and others. Especially in the field of dentistry, jewelry and related branches that require individualized or even one-of-a-kind products, the direct digital manufacturing process opens up new ways of design and manufacturing. In these fields, mostly small and medium sized businesses (SME) are operating which do not have sufficient human and economic resources to invest in this technology. But to stay competitive, the application of AM can be regarded as a necessity. In this situation a new desktop machine (Realizer SLM 50) was introduced that cost about 1/3 of a shop floor SLM machine and promises small quality parts. To find out whether the machine really is an alternative for SMEs the University of Applied Science, Aachen, Germany, designed, build and optimized typical parts from the dentistry and the jewelry branches using CoCr and silver material, the latter being new with this application. The paper describes the SLM procedure and how to find and optimize the most important parameters. The test is accompanied by digital simulation in order to verify the build parameters and to plan future builds. The procedure is shown as well as the resulting parts made from CoCr and silver material.}, language = {en} } @article{KirsteinMuellerWaleckiMingersetal.2012, author = {Kirstein, Simon and M{\"u}ller, Karsten and Walecki-Mingers, Mark and Deserno, Thomas M.}, title = {Robust adaptive flow line detection in sewer pipes}, series = {Automation in construction}, journal = {Automation in construction}, number = {21}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1872-7891 (E-Journal) ; 0926-5805 (Print)}, doi = {10.1016/j.autcon.2011.05.009}, pages = {24 -- 31}, year = {2012}, abstract = {As part of a novel approach to automatic sewer inspection, this paper presents a robust algorithm for automatic flow line detection. A large image repository is obtained from about 50,000 m sewers to represent the high variability of real world sewer systems. Automatic image processing combines Canny edge detection, Hough transform for straight lines and cost minimization using Dijkstra's shortest path algorithm. Assuming that flow lines are mostly smoothly connected horizontal structures, piecewise flow line delineation is reduced to a process of selecting adjacent line candidates. Costs are derived from the gap between adjacent candidates and their reliability. A single parameter α enables simple control of the algorithm. The detected flow line may precisely follow the segmented edges (α = 0.0) or minimize gaps at joints (α = 1.0). Both, manual and ground truth-based analysis indicate that α = 0.8 is optimal and independent of the sewer's material. The algorithm forms an essential step to further automation of sewer inspection.}, language = {en} } @article{KurulganDemirciDemirciLinderetal.2012, author = {Kurulgan Demirci, Eylem and Demirci, Taylan and Linder, Peter and Trzewik, J{\"u}rgen and Gierkowski, Jessica Ricarda and Gossmann, Matthias and Kayser, Peter and Porst, Dariusz and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l}, title = {rhAPC reduces the endothelial cell permeability via a decrease of contractile tensions induced by endothelial cells}, series = {Journal of Bioscience and Bioengineering}, volume = {113}, journal = {Journal of Bioscience and Bioengineering}, number = {2}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1347-4421}, doi = {10.1016/j.jbiosc.2012.03.019}, pages = {212 -- 219}, year = {2012}, abstract = {All cells generate contractile tension. This strain is crucial for mechanically controlling the cell shape, function and survival. In this study, the CellDrum technology quantifying cell's (the cellular) mechanical tension on a pico-scale was used to investigate the effect of lipopolysaccharide (LPS) on human aortic endothelial cell (HAoEC) tension. The LPS effect during gram-negative sepsis on endothelial cells is cell contraction causing endothelium permeability increase. The aim was to finding out whether recombinant activated protein C (rhAPC) would reverse the endothelial cell response in an in-vitro sepsis model. In this study, the established in-vitro sepsis model was confirmed by interleukin 6 (IL-6) levels at the proteomic and genomic levels by ELISA, real time-PCR and reactive oxygen species (ROS) activation by florescence staining. The thrombin cellular contraction effect on endothelial cells was used as a positive control when the CellDrum technology was applied. Additionally, the Ras homolog gene family, member A (RhoA) mRNA expression level was checked by real time-PCR to support contractile tension results. According to contractile tension results, the mechanical predominance of actin stress fibers was a reason of the increased endothelial contractile tension leading to enhanced endothelium contractility and thus permeability enhancement. The originality of this data supports firstly the basic measurement principles of the CellDrum technology and secondly that rhAPC has a beneficial effect on sepsis influenced cellular tension. The technology presented here is promising for future high-throughput cellular tension analysis that will help identify pathological contractile tension responses of cells and prove further cell in-vitro models.}, language = {en} } @article{HerzwurmKramsPietschetal.2012, author = {Herzwurm, Georg and Krams, Benedikt and Pietsch, Wolfram and Schockert, Sixten}, title = {Report from the 3rd international workshop on requirements prioritization for customer oriented software development (RePriCo'12)}, series = {ACM SIGSOFT Software Engineering Notes}, volume = {37}, journal = {ACM SIGSOFT Software Engineering Notes}, number = {4}, publisher = {Association for Computing Machinery}, address = {New York}, issn = {0163-5948}, doi = {10.1145/2237796.2237817}, pages = {32 -- 34}, year = {2012}, abstract = {Prioritization is an essential task within requirements engineering to cope with complexity and to establish focus properly. The 3rd Workshop on Requirements Prioritization for customer oriented Software Development (RePriCo'12) focused on requirements prioritization and adjacent themes in the context of customer oriented development of bespoke and standard software. Five submissions have been accepted for the proceedings and for presentation. The report summarizes and points out key findings.}, language = {en} } @article{Lind2012, author = {Lind, Thorsten Patric}, title = {Rechtsprobleme bei der Liquidation der GmbH und der Gewinnaussch{\"u}ttung trotz bestehenden Anspruchs gegen den Gesellschafter : BGH, Urteil vom 23.04.2012 - II ZR 252/10 : Anmerkung}, series = {Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-M{\"o}hring}, journal = {Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-M{\"o}hring}, number = {Ausg. 10}, publisher = {Beck}, address = {M{\"u}nchen}, issn = {1611-1095}, pages = {338415}, year = {2012}, language = {de} } @article{LeidingerNoistenWollert2012, author = {Leidinger, Rafael and Noisten, Thomas and Wollert, J{\"o}rg}, title = {Realtime automation networks in moVing industrial environments}, series = {Journal of systemics, cybernetics and informatics}, volume = {Vol. 10}, journal = {Journal of systemics, cybernetics and informatics}, number = {Iss. 2}, publisher = {IIIC}, address = {Orlando}, issn = {1690-4532}, pages = {52 -- 56}, year = {2012}, abstract = {The radio-based wireless data communication has made the realization of new technical solutions possible in many fields of the automation technology (AT). For about ten years, a constant disproportionate growth of wireless technologies can be observed in the automation technology. However, it shows that especially for the AT, conventional technologies of office automation are unsuitable and/or not manageable. The employment of mobile services in the industrial automation technology has the potential of significant cost and time savings. This leads to an increased productivity in various fields of the AT, for example in the factory and process automation or in production logistics. In this paper technologies and solutions for an automation-suited supply of mobile wireless services will be introduced under the criteria of real time suitability, IT-security and service orientation. Emphasis will be put on the investigation and development of wireless convergence layers for different radio technologies, on the central provision of support services for an easy-to-use, central, backup enabled management of combined wired / wireless networks and on the study on integrability in a Profinet real-time Ethernet network.}, language = {en} } @article{KirchnerOberlaenderFriedrichetal.2012, author = {Kirchner, Patrick and Oberl{\"a}nder, Jan and Friedrich, Peter and Berger, J{\"o}rg and Rysstad, Gunnar and Sch{\"o}ning, Michael Josef and Keusgen, Michael}, title = {Realisation of a calorimetric gas sensor on polyimide foil for applications in aseptic food industry}, series = {Sensors and Actuators B: Chemical}, volume = {170}, journal = {Sensors and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2011.01.032}, pages = {60 -- 66}, year = {2012}, abstract = {A calorimetric gas sensor is presented for the monitoring of vapour-phase H2O2 at elevated temperature during sterilisation processes in aseptic food industry. The sensor was built up on a flexible polyimide foil (thickness: 25 μm) that has been chosen due to its thermal stability and low thermal conductivity. The sensor set-up consists of two temperature-sensitive platinum thin-film resistances passivated by a layer of SU-8 photo resist and catalytically activated by manganese(IV) oxide. Instead of an active heating structure, the calorimetric sensor utilises the elevated temperature of the evaporated H2O2 aerosol. In an experimental test rig, the sensor has shown a sensitivity of 4.78 °C/(\%, v/v) in a H2O2 concentration range of 0\%, v/v to 8\%, v/v. Furthermore, the sensor possesses the same, unchanged sensor signal even at varied medium temperatures between 210 °C and 270 °C of the gas stream. At flow rates of the gas stream from 8 m3/h to 12 m3/h, the sensor has shown only a slightly reduced sensitivity at a low flow rate of 8 m3/h. The sensor characterisation demonstrates the suitability of the calorimetric gas sensor for monitoring the efficiency of industrial sterilisation processes.}, language = {en} } @article{BleckenHolthausSellheier2012, author = {Blecken, Udo and Holthaus-Sellheier, Ursula}, title = {Quantitative Prognoseverfahren f{\"u}r Mietpreise von Bueroimmobilien am Beispiel D{\"u}sseldorf}, series = {GuG : Grundst{\"u}cksmarkt und Grundst{\"u}ckswert}, volume = {23}, journal = {GuG : Grundst{\"u}cksmarkt und Grundst{\"u}ckswert}, number = {1}, publisher = {Werner}, address = {K{\"o}ln}, issn = {0938-0175}, pages = {12 -- 21}, year = {2012}, language = {de} } @article{HoetterFateriGebhardt2012, author = {H{\"o}tter, Jan-Steffen and Fateri, Miranda and Gebhardt, Andreas}, title = {Prozessoptimierung des SLM-Prozesses mit hoch-reflektiven und thermisch sehr gut leitenden Materialien durch systematische Parameterfindung und begleitende Simulationen am Beispiel von Silber}, series = {RTejournal - Forum f{\"u}r Rapid Technologie}, volume = {9}, journal = {RTejournal - Forum f{\"u}r Rapid Technologie}, number = {1}, publisher = {Fachhoschule Aachen}, address = {Aachen}, issn = {1614-0923}, url = {http://nbn-resolving.de/urn:nbn:de:0009-2-33639}, pages = {1 -- 14}, year = {2012}, abstract = {Additive Manufacturing durch Aufschmelzen von Metallpulvern hat sich auf breiter Front als Herstellverfahren, auch f{\"u}r Endprodukte, etabliert. Besonders f{\"u}r die Variante des Selective Laser Melting (SLM) sind Anwendungen in der Zahntechnik bereits weit verbreitet und der Einsatz in sensitiven Branchen wie der Luftfahrt ist in greifbare N{\"a}he ger{\"u}ckt. Deshalb werden auch vermehrt Anstrengungen unternommen, um bisher nicht verarbeitete Materialien zu qualifizieren. Dies sind vorzugsweise Nicht-Eisen- und Edelmetalle, die sowohl eine sehr hohe Reflektivit{\"a}t als auch eine sehr gute W{\"a}rmeleitf{\"a}higkeit aufweisen - beides Eigenschaften, die die Beherrschung des Laser-Schmelzprozesses erschweren und nur kleine Prozessfenster zulassen. Die Arbeitsgruppe SLM des Lehr- und Forschungsgebietes Hochleistungsverfahren der Fertigungstechnik hat sich unter der Randbedingung einer kleinen und mit geringer Laserleistung ausgestatteten SLM Maschine der Aufgabe gewidmet und am Beispiel von Silber die Parameterfelder f{\"u}r Einzelspuren und wenig komplexe Geometrien systematisch untersucht. Die Arbeiten wurden von FEM Simulationen begleitet und durch metallographische Untersuchungen verifiziert. Die Ergebnisse bilden die Grundlage zur schnellen Parameterfindung bei komplexen Geometrien und bei Ver{\"a}nderungen der Zusammensetzung, wie sie bei zuk{\"u}nftigen Legierungen zu erwarten sind. Die Ergebnisse werden exemplarisch auf unterschiedliche Geometrien angewandt und entsprechende Bauteile gezeigt.}, language = {de} } @article{HenkenOosterhuisOehlschlaegeretal.2012, author = {Henken, F. E. and Oosterhuis, K. and {\"O}hlschl{\"a}ger, Peter and Bosch, L. and Hooijberg, E. and Haanen, J. B. A. G. and Steenbergen, R. D. M.}, title = {Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7}, series = {Vaccine}, volume = {30}, journal = {Vaccine}, number = {28}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0264-410X}, doi = {10.1016/j.vaccine.2012.04.013}, pages = {4259 -- 4266}, year = {2012}, abstract = {Persistent infection with high-risk human papillomaviruses (hrHPV) can result in the formation of anogenital cancers. As hrHPV proteins E6 and E7 are required for cancer initiation and maintenance, they are ideal targets for immunotherapeutic interventions. Previously, we have described the development of DNA vaccines for the induction of HPV16 E6 and E7 specific T cell immunity. These vaccines consist of 'gene-shuffled' (SH) versions of HPV16 E6 and E7 that were fused to Tetanus Toxin Fragment C domain 1 (TTFC) and were named TTFC-E6SH and TTFC-E7SH. Gene-shuffling was performed to avoid the risk of inducing malignant transformation at the vaccination site. Here, we describe the preclinical safety evaluation of these candidate vaccines by analysis of their transforming capacity in vitro using established murine fibroblasts (NIH 3T3 cells) and primary human foreskin keratinocytes (HFKs). We demonstrate that neither ectopic expression of TTFC-E6SH and TTFC-E7SH alone or in combination enabled NIH 3T3 cells to form colonies in soft agar. In contrast, expression of HPV16 E6WT and E7WT alone or in combination resulted in effective transformation. Similarly, retroviral transduction of HFKs from three independent donors with both TTFC-E6SH and TTFC-E7SH alone or in combination did not show any signs of immortalization. In contrast, the combined expression of E6WT and E7WT induced immortalization in HFKs from all donors. Based on these results we consider it justified to proceed to clinical evaluation of DNA vaccines encoding TTFC-E6SH and TTFC-E7SH in patients with HPV16 associated (pre)malignancies.}, language = {en} } @article{GutheilBergGrotendorst2012, author = {Gutheil, Inge and Berg, Tommy and Grotendorst, Johannes}, title = {Performance Analysis of Parallel Eigensolvers of two Libraries on BlueGene/P}, series = {Journal of Mathematics and Systems Science}, volume = {2}, journal = {Journal of Mathematics and Systems Science}, number = {4}, publisher = {David Publishing}, address = {Libertyville}, issn = {2159-5291}, doi = {10.17265/2159-5291/2012.04.003}, pages = {231 -- 236}, year = {2012}, abstract = {Many applications in computational science and engineering require the computation of eigenvalues and vectors of dense symmetric or Hermitian matrices. For example, in DFT (density functional theory) calculations on modern supercomputers 10\% to 30\% of the eigenvalues and eigenvectors of huge dense matrices have to be calculated. Therefore, performance and parallel scaling of the used eigensolvers is of upmost interest. In this article different routines of the linear algebra packages ScaLAPACK and Elemental for parallel solution of the symmetric eigenvalue problem are compared concerning their performance on the BlueGene/P supercomputer. Parameters for performance optimization are adjusted for the different data distribution methods used in the two libraries. It is found that for all test cases the new library Elemental which uses a two-dimensional element by element distribution of the matrices to the processors shows better performance than the old ScaLAPACK library which uses a block-cyclic distribution.}, language = {en} } @article{BoettcherHaselhuhnJakseetal.2012, author = {Boettcher, Martin and Haselhuhn, Angelika and Jakse, Gerhard and Brehmer, Bernhard and Kirschner-Hermanns, Ruth}, title = {Overactive bladder syndrome: an underestimated long-term problem after treatment of patients with localized prostate cancer?}, series = {BJU international}, volume = {109}, journal = {BJU international}, number = {12}, publisher = {Wiley-Blackwell}, address = {Oxford}, issn = {1365-2176 (E-Journal); 1464-410X (E-Journal); 0007-1331 (Print); 1464-4096 (Print)}, doi = {10.1111/j.1464-410X.2011.10623.x}, pages = {1824 -- 1830}, year = {2012}, abstract = {In this study we observed courses of micturition symptoms and differentiated degrees of symptoms for each point in time while also considering the impact of bothersomeness. Our data show that not only significantly more patients who have undergone BT suffer from OAB than those who have undergone RP, but also that those affected show significantly higher values for severity of OAB symptoms throughout the whole observation period of 36 months. Our data analysis further shows that variability of OAB symptoms as well as fluctuation of severity of OAB symptoms vary to a significantly higher degree after BT than after RP. Looking only at mean figures at a given point in time clearly underestimates the underlying problem. This fact is not reflected in the literature.}, language = {en} } @article{ReisgenSchleserMokrovetal.2012, author = {Reisgen, Uwe and Schleser, Markus and Mokrov, Oleg and Ahmed, Essam}, title = {Optimization of laser welding of DP/TRIP steel sheets using statistical approach}, series = {Optics and laser technology}, volume = {44}, journal = {Optics and laser technology}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1879-2545 (E-Journal); 0030-3992 (Print); 0308-4280 (Print)}, doi = {10.1016/j.optlastec.2011.06.028}, pages = {255 -- 262}, year = {2012}, abstract = {Generally, the quality of a weld joint is directly influenced by the welding input parameter settings. Selection of proper process parameters is important to obtain the desired weld bead profile and quality. In this research work, numerical and graphical optimization techniques of the CO2 laser beam welding of dual phase (DP600)/transformation induced plasticity (TRIP700) steel sheets were carried out using response surface methodology (RSM) based on Box-Behnken design. The procedure was established to improve the weld quality, increase the productivity and minimize the total operation cost by considering the welding parameters range of laser power (2-2.2 kW), welding speed (40-50 mm/s) and focus position (-1 to 0 mm). It was found that, RSM can be considered as a powerful tool in experimental welding optimization, even when the experimenter does not have a model for the process. Strong, efficient and low cost weld joints could be achieved using the optimum welding conditions.}, language = {en} } @article{AggarwalDhimanKumaretal.2012, author = {Aggarwal, P. and Dhiman, S. and Kumar, G. and Scherer, Ulrich W. and Singla, M. L. and Srivastava, A.}, title = {Optical study of poly(ethyleneterephthalate) modified by different ionizing radiation dose}, series = {Indian Journal of Pure and Applied Physics}, volume = {50}, journal = {Indian Journal of Pure and Applied Physics}, number = {2}, issn = {0019-5596}, pages = {129 -- 132}, year = {2012}, abstract = {Thin films of poly(ethyleneterephthalate) [PET]were exposed to radiation dose ranging from 10 to 30 kGy by using gamma rays in the range 12.8-177.8 MGy using swift light ions of hydrogen. There was no effect of the radiation dose on the optical behaviour of PET as a result of exposure to radiation dose up to 30 kGy brought about by gamma rays but a significant decrease in the optical band gap values was observed when PET was exposed to swift light ions of hydrogen. The data obtained are discussed in terms of optical studies carried out on PET using swift heavy ions.}, language = {en} } @article{OlbertzFahrig2012, author = {Olbertz, Klaus and Fahrig, Stephan}, title = {Offshoring als Betriebs(teil){\"u}bergang gem{\"a}ß \S 613a BGB}, series = {ZIP Zeitschrift f{\"u}r Wirtschaftsrecht}, journal = {ZIP Zeitschrift f{\"u}r Wirtschaftsrecht}, number = {42}, publisher = {Verlag Dr. Otto Schmidt}, address = {K{\"o}ln}, issn = {0723-9416}, pages = {2045}, year = {2012}, language = {de} } @article{WernerGroebelKrumbeetal.2012, author = {Werner, Frederik and Groebel, Simone and Krumbe, Christoph and Wagner, Torsten and Selmer, Thorsten and Yoshinobu, Tatsuo and Baumann, Marcus and Sch{\"o}ning, Michael Josef}, title = {Nutrient concentration-sensitive microorganism-based biosensor}, series = {Physica Status Solidi (a)}, volume = {209}, journal = {Physica Status Solidi (a)}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201100801}, pages = {900 -- 904}, year = {2012}, language = {en} } @article{IkenKirsanovLeginetal.2012, author = {Iken, Heiko and Kirsanov, D. and Legin, A. and Sch{\"o}ning, Michael Josef}, title = {Novel Thin-Film Polymeric Materials for the Detection of Heavy Metals}, series = {Procedia Engineering}, journal = {Procedia Engineering}, number = {47}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1877-7058}, doi = {10.1016/j.proeng.2012.09.148}, pages = {322 -- 325}, year = {2012}, abstract = {A variety of transition metals, e.g., copper, zinc, cadmium, lead, etc. are widely used in industry as components for wires, coatings, alloys, batteries, paints and so on. The inevitable presence of transition metals in industrial processes implies the ambition of developing a proper analytical technique for their adequate monitoring. Most of these elements, especially lead and cadmium, are acutely toxic for biological organisms. Quantitative determination of these metals at low activity levels in different environmental and industrial samples is therefore a vital task. A promising approach to achieve an at-side or on-line monitoring on a miniaturized and cost efficient way is the combination of a common potentiometric sensor array with heavy metal-sensitive thin-film materials, like chalcogenide glasses and polymeric materials, respectively.}, language = {en} } @article{StaatTrenzLohmannetal.2012, author = {Staat, Manfred and Trenz, Eva and Lohmann, Philipp and Frotscher, Ralf and Klinge, Uwe and Tabaza, Ruth and Kirschner-Hermanns, Ruth}, title = {New measurements to compare soft tissue anchoring systems in pelvic floor surgery}, series = {Journal of Biomedical Materials Research Part B: Applied Biomaterials}, volume = {100B}, journal = {Journal of Biomedical Materials Research Part B: Applied Biomaterials}, number = {4}, publisher = {Wiley}, address = {Hoboken, NJ}, issn = {1552-4981}, doi = {10.1002/jbm.b.32654}, pages = {924 -- 933}, year = {2012}, abstract = {Suburethral slings as well as different meshes are widely used treating stress urinary incontinence and prolaps in women. With the development of MiniSlings and special meshes using less alloplastic material anchorage systems become more important to keep devices in place and to put some tension especially on the MiniSlings. To date, there are many different systems of MiniSlings of different companies on the market which differ in the structure of the used meshes and anchors. A new objective measurement method to compare different properties of MiniSling systems (mesh and anchor) is presented in this article. Ballistic gelatine acts as soft tissue surrogate. Significant differences in parameters like pull-out strength of anchors or shrinkage of meshes under loading conditions have been determined. The form and size of the anchors as well as the structural stability of the meshes are decisive for a proper integration. The tested anchorings sytems showed markedly different mechanical function at their respective load bearing capacity. As the stable fixation of the device in tissue is a prerequisite for a permanet reinforcement, the proposed test system permits further optimisation of anchor and mesh devices to improve the success of the surgical treatment}, language = {en} } @article{ButenwegHoltschoppen2012, author = {Butenweg, Christoph and Holtschoppen, Britta}, title = {Neuer VCI-Leitfaden f{\"u}r die erdbebensichere Auslegung von Industrieanlagen}, series = {Bauingenieur : die richtungsweisende Zeitschrift im Bauingenieurswesen ; offizielle Zeitschrift der VDI-Gesellschaft Bautechnik}, volume = {Band 87}, journal = {Bauingenieur : die richtungsweisende Zeitschrift im Bauingenieurswesen ; offizielle Zeitschrift der VDI-Gesellschaft Bautechnik}, publisher = {VDI Fachmedien}, address = {D{\"u}sseldorf}, issn = {1436-4867 (E-Journal); 0005-6650 (Print)}, pages = {S18}, year = {2012}, language = {de} } @article{BohrnStuetzFuchsetal.2012, author = {Bohrn, U. and St{\"u}tz, E. and Fuchs, K. and Fleischer, M. and Sch{\"o}ning, Michael Josef and Wagner, P.}, title = {Monitoring of irritant gas using a whole-cell-based sensor system}, series = {Sensors and Actuators B: Chemical}, volume = {175}, journal = {Sensors and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2012.05.088}, pages = {208 -- 217}, year = {2012}, abstract = {Cell-based sensors for the detection of gases have long been underrepresented, due to the cellular requirement of being cultured in a liquid environment. In this work we established a cell-based gas biosensor for the detection of toxic substances in air, by adapting a commercial sensor chip (Bionas®), previously used for the measurement of pollutants in liquids. Cells of the respiratory tract (A549, RPMI 2650, V79), which survive at a gas phase in a natural context, are used as biological receptors. The physiological cell parameters acidification, respiration and morphology are continuously monitored in parallel. Ammonia was used as a highly water-soluble model gas to test the feasibility of the sensor system. Infrared measurements confirmed the sufficiency of the medium draining method. This sensor system provides a basis for many sensor applications such as environmental monitoring, building technology and public security.}, language = {en} } @article{ReisgenSchleserMokrovetal.2012, author = {Reisgen, Uwe and Schleser, Markus and Mokrov, Oleg and Zabirov, Alexander and F{\"u}ssel, Uwe and Schnick, Michael and Hertel, Martin and Jaeckel, Sebastian}, title = {Modelling and visualisation of the GMA process}, series = {Welding and Cutting}, volume = {11}, journal = {Welding and Cutting}, number = {4}, publisher = {DVS Verlag}, address = {D{\"u}sseldorf}, issn = {1612-3433}, pages = {242 -- 249}, year = {2012}, language = {en} } @article{ReisgenSchleserMokrovetal.2012, author = {Reisgen, Uwe and Schleser, Markus and Mokrov, Oleg and Zabirov, Alexander and F{\"u}ssel, Uwe and Schnick, Michael and Hertel, Martin and Jaeckel, Sebastian}, title = {Modellierung und Visualisierung der MSG-Lichtbogenprozesse}, series = {Schweissen und Schneiden : Fachzeitschrift f{\"u}r Schweißen und verwandte Verfahren}, volume = {64}, journal = {Schweissen und Schneiden : Fachzeitschrift f{\"u}r Schweißen und verwandte Verfahren}, number = {4}, publisher = {DVS Verlag}, address = {D{\"u}sseldorf}, issn = {0036-7184}, pages = {166 -- 174}, year = {2012}, language = {de} } @article{ScheerKapelyukhMcEwanetal.2012, author = {Scheer, Nico and Kapelyukh, Yury and McEwan, Jillian and Beuger, Vincent and Stanley, Lesley A. and Rode, Anja and Wolf, C. Roland}, title = {Modeling Human Cytochrome P450 2D6 Metabolism and Drug-drug Interaction by a Novel Panel of Knockout and Humanized Mouse Lines}, series = {Molecular Pharmacology}, volume = {81}, journal = {Molecular Pharmacology}, number = {1}, publisher = {ASPET}, address = {Bethesda, Md.}, issn = {1521-0111}, doi = {10.1124/mol.111.075192}, pages = {63 -- 72}, year = {2012}, abstract = {The highly polymorphic human cytochrome P450 2D6 enzyme is involved in the metabolism of up to 25\% of all marketed drugs and accounts for significant individual differences in response to CYP2D6 substrates. Because of the differences in the multiplicity and substrate specificity of CYP2D family members among species, it is difficult to predict pathways of human CYP2D6-dependent drug metabolism on the basis of animal studies. To create animal models that reflect the human situation more closely and that allow an in vivo assessment of the consequences of differential CYP2D6 drug metabolism, we have developed a novel straightforward approach to delete the entire murine Cyp2d gene cluster and replace it with allelic variants of human CYP2D6. By using this approach, we have generated mouse lines expressing the two frequent human protein isoforms CYP2D6.1 and CYP2D6.2 and an as yet undescribed variant of this enzyme, as well as a Cyp2d cluster knockout mouse. We demonstrate that the various transgenic mouse lines cover a wide spectrum of different human CYP2D6 metabolizer phenotypes. The novel humanization strategy described here provides a robust approach for the expression of different CYP2D6 allelic variants in transgenic mice and thus can help to evaluate potential CYP2D6-dependent interindividual differences in drug response in the context of personalized medicine.}, language = {en} } @article{VerbanellaFabo2012, author = {Verbanella, Stresa and Fabo, Sabine}, title = {Mit Pinsel und Farbe hacken : Interview mit Sabine Fabo}, series = {Remotewords.net}, journal = {Remotewords.net}, year = {2012}, abstract = {Remotewords makes its mark on the picturesque "Bar Verbanella", located in Stresa near Isola Bella on Lago Maggiore. The words CUM GRANO SALIS (with a grain of salt) by Sabine Fabo, art theorist on media contexts, were applied to its roof in collaboration with the German-Italian art organization "Lo spirito del Lago".}, language = {de} } @article{MiyamotoKanekoMatsuoetal.2012, author = {Miyamoto, Ko-ichiro and Kaneko, Kazumi and Matsuo, Akira and Wagner, Torsten and Kanoh, Shin{\´i}chiro and Sch{\"o}ning, Michael Josef and Yoshinobu, Tatsuo}, title = {Miniaturized chemical imaging sensor system using an OLED display panel}, series = {Sensors and Actuators B: Chemical}, volume = {170}, journal = {Sensors and Actuators B: Chemical}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0925-4005}, doi = {10.1016/j.snb.2011.02.029}, pages = {82 -- 87}, year = {2012}, abstract = {The chemical imaging sensor is a semiconductor-based chemical sensor that can visualize the two-dimensional distribution of specific ions or molecules in the solution. In this study, we developed a miniaturized chemical imaging sensor system with an OLED display panel as a light source that scans the sensor plate. In the proposed configuration, the display panel is placed directly below the sensor plate and illuminates the back surface. The measured area defined by illumination can be arbitrarily customized to fit the size and the shape of the sample to be measured. The waveform of the generated photocurrent, the current-voltage characteristics and the pH sensitivity were investigated and pH imaging with this miniaturized system was demonstrated.}, language = {en} } @article{BaeckerRaueSchusseretal.2012, author = {B{\"a}cker, Matthias and Raue, Markus and Schusser, Sebastian and Jeitner, C. and Breuer, L. and Wagner, P. and Poghossian, Arshak and F{\"o}rster, Arnold and Mang, Thomas and Sch{\"o}ning, Michael Josef}, title = {Microfluidic chip with integrated microvalves based on temperature- and pH-responsive hydrogel thin films}, series = {Physica Status Solidi (a)}, volume = {209}, journal = {Physica Status Solidi (a)}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201100763}, pages = {839 -- 845}, year = {2012}, abstract = {Two types of microvalves based on temperature-responsive poly(N-isopropylacrylamide) (PNIPAAm) and pH-responsive poly(sodium acrylate) (PSA) hydrogel films have been developed and tested. The PNIPAAm and PSA hydrogel films were prepared by means of in situ photopolymerization directly inside the fluidic channel of a microfluidic chip fabricated by combining Si and SU-8 technologies. The swelling/shrinking properties and height changes of the PNIPAAm and PSA films inside the fluidic channel were studied at temperatures of deionized water from 14 to 36 °C and different pH values (pH 3-12) of Titrisol buffer, respectively. Additionally, in separate experiments, the lower critical solution temperature (LCST) of the PNIPAAm hydrogel was investigated by means of a differential scanning calorimetry (DSC) and a surface plasmon resonance (SPR) method. Mass-flow measurements have shown the feasibility of the prepared hydrogel films to work as an on-chip integrated temperature- or pH-responsive microvalve capable to switch the flow channel on/off.}, language = {en} } @article{LustfeldPithanReissel2012, author = {Lustfeld, H. and Pithan, C. and Reißel, Martin}, title = {Metallic electrolyte composites in the framework of the brick-layer model}, series = {Journal of the European Ceramic Society}, volume = {32}, journal = {Journal of the European Ceramic Society}, number = {4}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0955-2219}, doi = {10.1016/j.jeurceramsoc.2011.10.017}, pages = {859 -- 864}, year = {2012}, abstract = {It is well known that the already large dielectric constants of some electrolytes like BaTiO₃ can be enhanced further by adding metallic (e.g. Ni, Cu or Ag) nanoparticles. The enhancement can be quite large, a factor of more than 1000 is possible. The consequences for the properties will be discussed in the present paper applying a brick-layer model (BLM) for calculating dc-resistivities of thin layers and a modified one (PBLM) that includes percolation for calculating dielectric properties of these materials. The PBLM results in an at least qualitative description and understanding of the physical phenomena: This model gives an explanation for the steep increase of the dielectric constant below the percolation threshold and why this increase is connected to a dramatic decrease of the breakdown voltage as well as the ability of storing electrical energy. We conclude that metallic electrolyte composites like BaTiO₃ are not appropriate for energy storage.}, language = {en} } @article{ReisgenSchleserAbdurakhmanovetal.2012, author = {Reisgen, Uwe and Schleser, Markus and Abdurakhmanov, Aydemir and Gumenyuk, Andrey}, title = {Measuring of plasma properties induced by non-vacuum electron beam welding}, series = {Physics of plasma}, volume = {19}, journal = {Physics of plasma}, number = {1}, publisher = {AIP Publishing}, address = {Melville, NY}, issn = {1089-7674 (E-Journal); 1070-664X (Print)}, doi = {10.1063/1.3675874}, pages = {1 -- 7}, year = {2012}, abstract = {Electron beam plasma measurement was realised by means of DIABEAM system invented by ISF RWTH Aachen. The Langmuir probe method is used for measurement. The relative simplicity of the method and the possibility of dispersion of high power on the probe allow its application for the investigation of high-power electron beams. The key element of the method is a rotating thin tungsten wire, which intersects the beam transversely on its axis and collects part of the current by itself. The signals, which are registered in the DIABEAM as a voltage, were taken in the form of amplitude. The conversion of the probe current into the distribution along the beam radius was realised using the Abel's method. A voltage-current characteristic was built for the beam current. The local electron density as well as the electron temperature, the floating potential and the plasma potential were measured and calculated by means of this characteristic.}, language = {en} } @article{Staat2012, author = {Staat, Manfred}, title = {Limit and shakedown analysis under uncertainty}, series = {Tap chi Khoa hoc \& ung dung - Dai hoc Ton Duc Thang}, volume = {19}, journal = {Tap chi Khoa hoc \& ung dung - Dai hoc Ton Duc Thang}, pages = {45 -- 47}, year = {2012}, language = {en} }