@inproceedings{DigelDemirciTrzewiketal.2004,
  author    = {Digel, Ilya and Demirci, Taylan and Trzewik, J{\"u}rgen and Linder, Peter and Temiz Artmann, Ayseg{\"u}l},
  title     = {Fibroblast response to mechanical stress: role of the adhesion substrate : [abstract]},
  year      = {2004},
  abstract  = {Mechanical stimulation of the cells resulted in evident changes in the cell morphology, protein composition and gene expression. Microscopically, additional formation of stress fibers accompanied by cell re-arrangements in a monolayer was observed. Also, significant activation of p53 gene was revealed as compared to control. Interestingly, the use of CellTech membrane coating induced cell death after mechanical stress had been applied. Such an effect was not detected when fibronectin had been used as an adhesion substrate.},
  subject      = {Fibroblast},
  language  = {en}
}
@inproceedings{StadlerEmbsZerlinetal.2007,
  author    = {Stadler, Andreas M. and Embs, Jan P. and Zerlin, Kay and Digel, Ilya and Artmann, Gerhard and Zaccai, Joe and B{\"u}ldt, Georg},
  title     = {Temperature transitions of hemoglobin and cytosolic water diffusion in human red blood cells : [poster]},
  year      = {2007},
  abstract  = {Background Hemoglobin interactions in red blood cells Hemoglobin dynamics in human red blood cells Diffusion of H2O in red blood cells},
  subject      = {Erythrozyt},
  language  = {en}
}
@inproceedings{MansurovZhubanovaDigeletal.2008,
  author    = {Mansurov, Zulkhair and Zhubanova, Azhar A. and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l and Savitskaja, Irina S. and Kozhalakova, A. A. and Kistaubaeva, Aida S.},
  title     = {The sorption of LPS toxic shock by nanoparticles on base of carbonized vegetable raw materials},
  year      = {2008},
  abstract  = {Immobilization of lactobacillus on high temperature carbonizated vegetable raw material (rice husk, grape stones) increases their physiological activity and the quantity of the antibacterial metabolits, that consequently lead to increase of the antagonistic activity of lactobacillus. It is implies that the use of the nanosorbents for the attachment of the probiotical microorganisms are highly perspective for decision the important problems, such as the probiotical preparations delivery to the right address and their attachment to intestines mucosa with the following detoxication of gastro-intestinal tract and the normalization of it's microecology. Besides that, thus, the received carbonizated nanoparticles have peculiar properties - ability to sorption of LPS toxical shock and, hence, to the detoxication of LPS.},
  subject      = {Kohlenstofffaser},
  language  = {en}
}
@inproceedings{DigelDachwaldArtmannetal.2009,
  author    = {Digel, Ilya and Dachwald, Bernd and Artmann, Gerhard and Linder, Peter and Funke, O.},
  title     = {A concept of a probe for particle analysis and life detection in icy environments},
  year      = {2009},
  abstract  = {A melting probe equipped with autofluorescence-based detection system combined with a light scattering unit, and, optionally, with a microarray chip would be ideally suited to probe icy environments like Europa's ice layer as well as the polar ice layers of Earth and Mars for recent and extinct live.},
  subject      = {Sonde},
  language  = {en}
}
@inproceedings{BassamDigelArtmann2009,
  author    = {Bassam, Rasha and Digel, Ilya and Artmann, Gerhard},
  title     = {Effect of nitric oxide on protein thermal stability : [abstract]},
  year      = {2009},
  abstract  = {As a deduction from these results, we can conclude that proteins mainly in vitro, denaturate totally at a temperature between 57°C -62°C, and they also affected by NO and different ions types. In which mainly, NO cause earlier protein denaturation, which means that, NO has a destabilizing effect on proteins, and also different ions will alter the protein denaturation in which, some ions will cause earlier protein denaturation while others not.},
  subject      = {Stickstoffmonoxid},
  language  = {en}
}
@inproceedings{O'HerasDigelTemizArtmann2009,
  author    = {O\'Heras, Carlos and Digel, Ilya and Temiz Artmann, Ayseg{\"u}l},
  title     = {Nanostructured carbon-based column for LPS/protein adsorption : [abstract]},
  year      = {2009},
  abstract  = {The absence of a general method for endotoxin removal from liquid interfaces gives an opportunity to find new methods and materials to overcome this gap. Activated nanostructured carbon is a promising material that showed good adsorption properties due to its vast pore network and high surface area. The aim of this study is to find the adsorption rates for a carboneous material produced at different temperatures, as well as to reveal possible differences between the performance of the material for each of the adsorbates used during the study (hemoglobin, serum albumin and lipopolysaccharide, LPS).},
  subject      = {Kohlenstofffaser},
  language  = {en}
}
@inproceedings{ElBashirDigel2009,
  author    = {ElBashir, Rasha and Digel, Ilya},
  title     = {Effect of nitric oxide gas on hydrogels : [abstract]},
  year      = {2009},
  abstract  = {The results support our theory that the NO gas has an influence in increasing the translational diffusion of hydrogels and it accelerates the melting process of the gels.},
  subject      = {Stickstoffmonoxid},
  language  = {en}
}
@inproceedings{ArinkinDigel2009,
  author    = {Arinkin, Vladimir and Digel, Ilya},
  title     = {Water bridge phenomenon : [abstract]},
  year      = {2009},
  abstract  = {One of interesting but not well known water properties is related to appearance of highly ordered structures in response to strong electrical field. In 1893 Sir William Armstrong placed a cotton thread between two wine glasses filled with chemically pure water. When high DC voltage was applied between the glasses, a connection consisting of water formed, producing a "water bridge"},
  subject      = {Hydrodynamik},
  language  = {en}
}
@inproceedings{DigelLeimenaDachwaldetal.2010,
  author    = {Digel, Ilya and Leimena, W. and Dachwald, Bernd and Linder, Peter and Porst, Dariusz and Kayser, Peter and Funke, O. and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard},
  title     = {In-situ biological decontamination of an ice melting probe : [abstract]},
  year      = {2010},
  abstract  = {The objective of our study was to investigate the efficacy of different in-situ decontamination protocols in the conditions of thermo-mechanical ice-melting.},
  subject      = {Sonde},
  language  = {en}
}
@inproceedings{ArtmannStadlerEmbsetal.2010,
  author    = {Artmann, Gerhard and Stadler, Andreas M. and Embs, Jan P. and Zaccai, Giuseppe and B{\"u}ldt, Georg and Digel, Ilya and Temiz Artmann, Ayseg{\"u}l},
  title     = {The crucial role of water in a phase transition of hemoglobin at body temperature : [abstract]},
  year      = {2010},
  abstract  = {The observation of a temperature transition of hemoglobin occurring at a critical temperature close to body temperature},
  subject      = {H{\"a}moglobin},
  language  = {en}
}
@inproceedings{KurulganDemirciLinderDemircietal.2010,
  author    = {Kurulgan Demirci, Eylem and Linder, Peter and Demirci, Taylan and Gierkowski, Jessica R. and Digel, Ilya and Gossmann, Matthias and Temiz Artmann, Ayseg{\"u}l},
  title     = {rhAPC reduces the endothelial cell permeability via a decrease of cellular mechanical contractile tensions : [abstract]},
  year      = {2010},
  abstract  = {In this study, the CellDrum technology quanitfying cellular mechanical tension on a pico-scale was used to investigate the effect of LPS (lipopolysaccharide) on HAoEC (Human Aortic Endothelial Cell) tension.},
  subject      = {Endothelzelle},
  language  = {en}
}
@inproceedings{DachwaldXuFeldmannetal.2011,
  author    = {Dachwald, Bernd and Xu, Changsheng and Feldmann, Marco and Plescher, Engelbert and Digel, Ilya and Artmann, Gerhard},
  title     = {Development and testing of a subsurface probe for detection of life in deep ice : [abstract]},
  year      = {2011},
  abstract  = {We present the novel concept of a combined drilling and melting probe for subsurface ice research. This probe, named "IceMole", is currently developed, built, and tested at the FH Aachen University of Applied Sciences' Astronautical Laboratory. Here, we describe its first prototype design and report the results of its field tests on the Swiss Morteratsch glacier. Although the IceMole design is currently adapted to terrestrial glaciers and ice shields, it may later be modified for the subsurface in-situ investigation of extraterrestrial ice, e.g., on Mars, Europa, and Enceladus. If life exists on those bodies, it may be present in the ice (as life can also be found in the deep ice of Earth).},
  subject      = {Eisschicht},
  language  = {en}
}
@inproceedings{ArtmannDigelLinderetal.2011,
  author    = {Artmann, Gerhard and Digel, Ilya and Linder, Peter and Temiz Artmann, Ayseg{\"u}l},
  title     = {Biophysical and Engineering Contributions to Plant Research},
  year      = {2011},
  abstract  = {Tests with palm tree leaves have just started yet and scan data are in the process to be analyzed. The final goal of future project for palm tree gender and species recognition will be to develop optical scanning technology to be applied to date palm tree leaves for in-situ screening purposes. Depending on the software used and the particular requirements of the users the technology potentially shall be able to identify palm tree diseases, palm tree gender, and species of young date palm trees by scanning leaves.},
  subject      = {Pflanzenphysiologie},
  language  = {en}
}
@article{BogoyavlenskiyDigelBerezin1997,
  author    = {Bogoyavlenskiy, A. P. and Digel, Ilya and Berezin, V. E.},
  title     = {Assessment of dot-blot ELISA sensitivity on membrane sorbent using various peroxidase substrates},
  year      = {1997},
  abstract  = {The sensitivity of the peroxidase reaction in dot-blot ELISA significantly depends on the substrate. The highest sensitivity is observed using benzidine and diamine- phenol combinations as the substrates due to the reaction of the coupled oxidation (NADI)},
  subject      = {Enzyme-linked immunosorbent assay},
  language  = {en}
}
@article{ZhubanovaDigelNojimaetal.2007,
  author    = {Zhubanova, Azhar A. and Digel, Ilya and Nojima, H. and Artmann, Gerhard},
  title     = {The use of bactericidal effects of cluster ions generated by plasma in medical biotechnology},
  year      = {2007},
  abstract  = {The most of conventional methods of air purification use the power of a fan to draw in air and pass it through a filter. The problem of bacterial contamination of inner parts of such a type of air conditioners in some cases draws attention towards alternative air-cleaning systems. Some manufacturers offer to use the ozone's bactericidal and deodorizing effects, but the wide spreading of such systems is restricted by the fact that toxic effects of ozone in respect of human beings are well known. In 2000 Sharp Inc. introduced "Plasma Cluster Ions (PCI)" air purification technology, which uses plasma discharge to generate cluster ions (I 0-14 ). This technology has been developed for those customers that are conscious about health and hygiene. In our experiments, we focused on some principal aspects of plasma-generated ions application - time-dependency and irreversibility of bactericidal action, spatial and kinetic characteristics of emitted cluster particles, their chemical targets in the microbial cells.},
  subject      = {Clusterion},
  language  = {en}
}
@article{ZhubanovaAknazarovMansurovetal.2010,
  author    = {Zhubanova, Azhar A. and Aknazarov, S. K. and Mansurov, Zulkhair and Digel, Ilya and Kozhalakova, A. A. and Akimbekov, Nuraly Shardarbekovich and O'Heras, Carlos and Tazhibayeva, S. and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {Adsorption of bacterial Lipopolysaccharides and blood plasma proteins on modified carbonized materials},
  year      = {2010},
  abstract  = {Bacterial lipopolysaccharides (endotoxins) show strong biological effects at very low concentrations in human beings and many animals when entering the blood stream. These include affecting structure and function of organs and cells, changing metabolic functions, raising body temperature, triggering the coagulation cascade, modifying hemodynamics and causing septic shock. Because of this toxicity, the removal of even minute amounts is essential for safe parenteral administration of drugs and also for septic shock patients' care. The absence of a general method for endotoxin removal from liquid interfaces urgently requires finding new methods and materials to overcome this gap. Nanostructured carbonized plant parts is a promising material that showed good adsorption properties due to its vast pore network and high surface area. The aim of this study was comparative measurement of endotoxin- and blood proteins-related adsorption rate and adsorption capacity for different carboneous materials produced at different temperatures and under different surface modifications. As a main surface modificator, positively cbarged polymer, polyethileneimine (PEl) was used. Activated carbon materials showed good adsorption properties for LPS and some proteins used in the experiments. During the batch experiments, several techniques (dust removal, autoclaving) were used and optimized for improving the material's adsorption behavior. Also, with the results obtained it was possible to differentiate the materials according to their adsorption capacity and kinetic characteristics. Modification of the surface apparently has not affected hemoglobin binding to the adsorbent's surface. Obtained adsorption isotherms can be used as a powerful tool for designing of future column-based setups for blood purification from LPS, which is especially important for septic shock treatment.},
  subject      = {Kohlenstofffaser},
  language  = {en}
}
@article{SeifarthSchehlLinderetal.2011,
  author    = {Seifarth, Volker and Schehl, D. and Linder, Peter and Gossmann, Matthias and Digel, Ilya and Artmann, Gerhard and Porst, Dariusz and Preiß, C. and Kayser, Peter and Pack, O. and Temiz Artmann, Ayseg{\"u}l},
  title     = {Ureplace: development of a bioreactor for in vitro culturing of cell seeded tubular vessels on collagen scaffolds},
  year      = {2011},
  abstract  = {The demand of replacements for inoperable organs exceeds the amount of available organ transplants. Therefore, tissue engineering developed as a multidisciplinary field of research for autologous in-vitro organs. Such three dimensional tissue constructs request the application of a bioreactor. The UREPLACE bioreactor is used to grow cells on tubular collagen scaffolds OPTIMAIX Sponge 1 with a maximal length of 7 cm, in order to culture in vitro an adequate ureter replacement. With a rotating unit, (urothelial) cells can be placed homogeneously on the inner scaffold surface. Furthermore, a stimulation is combined with this bioreactor resulting in an orientation of muscle cells. These culturing methods request a precise control of several parameters and actuators. A combination of a LabBox and the suitable software LabVision is used to set and conduct parameters like rotation angles, velocities, pressures and other important cell culture values. The bioreactor was tested waterproof successfully. Furthermore, the temperature controlling was adjusted to 37 °C and the CO2 - concentration regulated to 5 \%. Additionally, the pH step responses of several substances showed a perfect functioning of the designed flow chamber. All used software was tested and remained stable for several days.},
  subject      = {Tissue Engineering},
  language  = {en}
}
@article{PreissLinderWendtetal.2011,
  author    = {Preiß, C. and Linder, Peter and Wendt, K. and Krystek, M. and Digel, Ilya and Gossmann, Matthias and Temiz Artmann, Ayseg{\"u}l and Porst, Dariusz and Kayser, Peter and Bassam, Rasha and Artmann, Gerhard},
  title     = {Engineering technology for plant physiology and plant stress research},
  year      = {2011},
  abstract  = {Plant physiology and plant stress: Plant physiology will be much more important for human mankind because of yield and cultivation limits of crops determined by their resistance to stress. To assess and counteract various stress factors it is necessary to conduct plant research to gain information and results on plant physiology.},
  subject      = {Pflanzenphysiologie},
  language  = {en}
}
@article{BassamArtmannHescheleretal.2011,
  author    = {Bassam, Rasha and Artmann, Gerhard and Hescheler, J{\"u}rgen and Graef, T. and Temiz Artmann, Ayseg{\"u}l and Porst, Dariusz and Linder, Peter and Kayser, Peter and Arinkin, Vladimir and Gossmann, Matthias and Digel, Ilya},
  title     = {Alterations in human hemoglobin structure related to red blood cell storage},
  year      = {2011},
  abstract  = {The importance of the availability of stored blood or blood cells, respectively, for urgent transfusion cannot be overestimated. Nowadays, blood storage becomes even more important since blood products are used for epidemiological studies, bio-technical research or banked for transfusion purposes. Thus blood samples must not only be processed, stored, and shipped to preserve their efficacy and safety, but also all parameters of storage must be recorded and reported for Quality Assurance. Therefore, blood banks and clinical research facilities are seeking more accurate, automated means for blood storage and blood processing.},
  subject      = {H{\"a}moglobin},
  language  = {en}
}
@inproceedings{SchoeningAbdelghani2012,
  author    = {Sch{\"o}ning, Michael Josef and Abdelghani, Adnane},
  title     = {Nanoscale Science and Technology (NS\&T'12) : Proceedings Book Humboldt Kolleg <2012, Tunisia> ; Tunisia, 17-19 March, 2012 / ed. by Michael J. Sch{\"o}ning ; Adnane Abdelghani},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-3544},
  year      = {2012},
  abstract  = {Proceedings of the 2nd Humboldt Kolleg, Hammamet, Tunisia Organizer: Alexander von Humboldt Stiftung, Germany. pdf 184 p. Welcome Address Dear Participants, Welcome to the 2nd Humboldt Kolleg in "Nanoscale Science and Technology" (NS\&T'12) in Tunisia, sponsored by the "Alexander von Humboldt" foundation. The NS\&T'12 multidisciplinary scientific program includes seven "hot" topics dealing with "Nanoscale Science and Technology" covering basic and application-oriented research as well as industrial (market) aspects: - Molecular Biophyics, Spectroscopy Techniques, Imaging Microscopy - Nanomaterials Synthesis for Medicine and Bio-chemical Sensors - Nanostructures, Semiconductors, Photonics and Nanodevices - New Technologies in Market Industry - Environment, Electro-chemistry, Bio-polymers and Fuel Cells - Nanomaterials, Photovoltaic, Modelling, Quantum Physics - Microelectronics, Sensors Networks and Embedded Systems We are deeply indebted to all members of the Scientific Committee and General Chairs for joint Sessions and to all speakers and chairmen, who have dedicated invaluable time and efforts for the realization of this event. On behalf of the Organizing Committee, we are cordially inviting you to join the conference and hope that your stay will be fruitful, rewarding and enjoyable. Prof. Dr. Michael J. Sch{\"o}ning, Prof. Dr. Adnane Abdelghani},
  subject      = {Biosensor},
  language  = {en}
}
@inproceedings{TranNovacekTolbaetal.2011,
  author    = {Tran, Thanh Ngoc and Novacek, V. and Tolba, R. and Klinge, U. and Turquier, F. and Staat, Manfred},
  title     = {Experimental and Computational approach to study colorectal anastomosis. ISB2011, Proceedings of the XXIII Congress of the International Society of Biomechanics, Brussels, Belgium, July 3-7, 2011},
  year      = {2011},
  abstract  = {Summary: This paper presents a methodology to study and understand the mechanics of stapled anastomotic behaviors by combining empirical experimentation and finite element analysis. Performance of stapled anastomosis is studied in terms of leakage and numerical results which are compared to in vitro experiments performed on fresh porcine tissue. Results suggest that leaks occur between the tissue and staple legs penetrating through the tissue.},
  subject      = {Anastomose},
  language  = {en}
}
@article{StaatBallmann1988,
  author    = {Staat, Manfred and Ballmann, J.},
  title     = {Computation of impacts on elastic solids by methods of bicharacteristics},
  series = {Computational Mechanics '88 : theory and applications ; proceedings of the International Conference on Computational Engineering Science April 10-14, 1988, Atlanta, GA, USA ; vol. 2},
  journal   = {Computational Mechanics '88 : theory and applications ; proceedings of the International Conference on Computational Engineering Science April 10-14, 1988, Atlanta, GA, USA ; vol. 2},
  pages     = {1719 -- 1722},
  year      = {1988},
  abstract  = {Shock waves, explosions, impacts or cavitation bubble collapses may generate stress waves in solids causing cracks or unexpected dammage due to focussing, physical nonlinearity or interaction with existing cracks. There is a growing interest in wave propagation, which poses many novel problems to experimentalists and theorists.},
  subject      = {Bicharakteristikenverfahren},
  language  = {en}
}
@article{KraftNagl2007,
  author    = {Kraft, Bodo and Nagl, Manfred},
  title     = {Visual Knowledge Specification for Conceptual Design: Definition and Tool Support},
  year      = {2007},
  abstract  = {In: Advanced Engineering Informatics. Vol 21, Issue 1, 2007, Pages 67-83 http://dx.doi.org/10.1016/j.aei.2006.10.001 eds. J.C. Kunz, I.F.C. Smith and T. Tomiyama, Elsevier, Seite 1-22 Current CAD tools are not able to support the conceptual design phase, and none of them provides a consistency analysis for sketches produced by architects. This phase is fundamental and crucial for the whole design and construction process of a building. To give architects a better support, we developed a CAD tool for conceptual design and a knowledge specification tool. The knowledge is specific to one class of buildings and it can be reused. Based on a dynamic and domain-specific knowledge ontology, different types of design rules formalize this knowledge in a graph-based form. An expressive visual language provides a user-friendly, human readable representation. Finally, a consistency analysis tool enables conceptual designs to be checked against this formal conceptual knowledge. In this article, we concentrate on the knowledge specification part. For that, we introduce the concepts and usage of a novel visual language and describe its semantics. To demonstrate the usability of our approach, two graph-based visual tools for knowledge specification and conceptual design are explained.},
  subject      = {CAD},
  language  = {en}
}
@inproceedings{KraftRetkowitz2006,
  author    = {Kraft, Bodo and Retkowitz, Daniel},
  title     = {Rule-Dependencies for Visual Knowledge Specification in Conceptual Design},
  year      = {2006},
  abstract  = {In: Proc. of the 11th Intl. Conf. on Computing in Civil and Building Engineering (ICCCBE-XI) ed. Hugues Rivard, Montreal, Canada, Seite 1-12, ACSE (CD-ROM), 2006 Currently, the conceptual design phase is not adequately supported by any CAD tool. Neither the support while elaborating conceptual sketches, nor the automatic proof of correctness with respect to effective restrictions is currently provided by any commercial tool. To enable domain experts to store the common as well as their personal domain knowledge, we develop a visual language for knowledge formalization. In this paper, a major extension to the already existing concepts is introduced. The possibility to define rule dependencies extends the expressiveness of the knowledge definition language and contributes to the usability of our approach.},
  subject      = {CAD},
  language  = {en}
}
@inproceedings{KraftWilhelms2005,
  author    = {Kraft, Bodo and Wilhelms, Nils},
  title     = {Visual Knowledge Specification for Conceptual Design},
  year      = {2005},
  abstract  = {Proc. of the 2005 ASCE Intl. Conf. on Computing in Civil Engineering (ICCC 2005) eds. L. Soibelman und F. Pena-Mora, Seite 1-14, ASCE (CD-ROM), Cancun, Mexico, 2005 Current CAD tools are not able to support the fundamental conceptual design phase, and none of them provides consistency analyses of sketches produced by architects. To give architects a greater support at the conceptual design phase, we develop a CAD tool for conceptual design and a knowledge specification tool allowing the definition of conceptually relevant knowledge. The knowledge is specific to one class of buildings and can be reused. Based on a dynamic knowledge model, different types of design rules formalize the knowledge in a graph-based realization. An expressive visual language provides a user-friendly, human readable representation. Finally, consistency analyses enable conceptual designs to be checked against this defined knowledge. In this paper we concentrate on the knowledge specification part of our project.},
  subject      = {CAD},
  language  = {en}
}
@inproceedings{KraftSchneider2005,
  author    = {Kraft, Bodo and Schneider, Gerd},
  title     = {Semantic Roomobjects for Conceptual Design Support : A Knowledge-based Approach},
  isbn      = {978-1-4020-3460-2},
  year      = {2005},
  abstract  = {In: Computer Aided Architectural Design Futures 2005 2005, Part 4, 207-216, DOI: http://dx.doi.org/10.1007/1-4020-3698-1_19 The conceptual design at the beginning of the building construction process is essential for the success of a building project. Even if some CAD tools allow elaborating conceptual sketches, they rather focus on the shape of the building elements and not on their functionality. We introduce semantic roomobjects and roomlinks, by way of example to the CAD tool ArchiCAD. These extensions provide a basis for specifying the organisation and functionality of a building and free architects being forced to directly produce detailed constructive sketches. Furthermore, we introduce consistency analyses of the conceptual sketch, based on an ontology containing conceptual relevant knowledge, specific to one class of buildings.},
  subject      = {CAD},
  language  = {en}
}
@inproceedings{KirchhofKraft2004,
  author    = {Kirchhof, M. and Kraft, Bodo},
  title     = {UML-based modeling of architectural knowledge and design},
  year      = {2004},
  abstract  = {IASSE-2004 - 13th International Conference on Intelligent and Adaptive Systems and Software Engineering eds. W. Dosch, N. Debnath, pp. 245-250, ISCA, Cary, NC, 1-3 July 2004, Nice, France We introduce a UML-based model for conceptual design support in civil engineering. Therefore, we identify required extensions to standard UML. Class diagrams are used for elaborating building typespecific knowledge: Object diagrams, implicitly contained in the architect's sketch, are validated against the defined knowledge. To enable the use of industrial, domain-specific tools, we provide an integrated conceptual design extension. The developed tool support is based on graph rewriting. With our approach architects are enabled to deal with semantic objects during early design phase, assisted by incremental consistency checks.},
  subject      = {UML},
  language  = {en}
}
@inproceedings{KraftWilhelms2004,
  author    = {Kraft, Bodo and Wilhelms, N.},
  title     = {Interactive distributed knowledge support for conceptual building design},
  isbn      = {3-86068-213-X},
  year      = {2004},
  abstract  = {In: Net-distributed Co-operation : Xth International Conference on Computing in Civil and Building Engineering, Weimar, June 02 - 04, 2004 ; proceedings / [ed. by Karl Beuke ...] . - Weimar: Bauhaus-Univ. Weimar 2004. - 1. Aufl. . Seite 1-14 ISBN 3-86068-213-X International Conference on Computing in Civil and Building Engineering <10, 2004, Weimar> Summary In our project, we develop new tools for the conceptual design phase. During conceptual design, the coarse functionality and organization of a building is more important than a detailed worked out construction. We identify two roles, first the knowledge engineer who is responsible for knowledge definition and maintenance; second the architect who elaborates the conceptual de-sign. The tool for the knowledge engineer is based on graph technology, it is specified using PROGRES and the UPGRADE framework. The tools for the architect are integrated to the in-dustrial CAD tool ArchiCAD. Consistency between knowledge and conceptual design is en-sured by the constraint checker, another extension to ArchiCAD.},
  subject      = {CAD},
  language  = {en}
}
@inproceedings{KraftNagl2003,
  author    = {Kraft, Bodo and Nagl, Manfred},
  title     = {Semantic tool support for conceptual design},
  year      = {2003},
  abstract  = {ITCE-2003 - 4th Joint Symposium on Information Technology in Civil Engineering ed Flood, I., Seite 1-12, ASCE (CD-ROM), Nashville, USA In this paper we discussed graph based tools to support architects during the conceptual design phase. Conceptual Design is defined before constructive design; the used concepts are more abstract. We develop two graph based approaches, a topdown using the graph rewriting system PROGRES and a more industrially oriented approach, where we extend the CAD system ArchiCAD. In both approaches, knowledge can be defined by a knowledge engineer, in the top-down approach in the domain model graph, in the bottom-up approach in the in an XML file. The defined knowledge is used to incrementally check the sketch and to inform the architect about violations of the defined knowledge. Our goal is to discover design error as soon as possible and to support the architect to design buildings with consideration of conceptual knowledge.},
  subject      = {CAD},
  language  = {en}
}
@inproceedings{Kraft2004,
  author    = {Kraft, Bodo},
  title     = {Conceptual design tools for civil engineering},
  year      = {2004},
  abstract  = {Applications of Graph Transformations with Industrial Relevance Lecture Notes in Computer Science, 2004, Volume 3062/2004, 434-439, DOI: http://dx.doi.org/10.1007/978-3-540-25959-6_33 This paper gives a brief overview of the tools we have developed to support conceptual design in civil engineering. Based on the UPGRADE framework, two applications, one for the knowledge engineer and another for architects allow to store domain specific knowledge and to use this knowledge during conceptual design. Consistency analyses check the design against the defined knowledge and inform the architect if rules are violated.},
  subject      = {CAD},
  language  = {en}
}
@inproceedings{KraftMeyerNagl2002,
  author    = {Kraft, Bodo and Meyer, Oliver and Nagl, Manfred},
  title     = {Graph technology support for conceptual design in civil engineering},
  isbn      = {3-18-318004-9},
  year      = {2002},
  abstract  = {In: Advances in intelligent computing in engineering : proceedings of the 9.International EG-ICE Workshop ; Darmstadt, (01 - 03 August) 2002 / Martina Schnellenbach-Held ... (eds.) . - D{\"u}sseldorf: VDI-Verl., 2002 .- Fortschritt-Berichte VDI, Reihe 4, Bauingenieurwesen ; 180 ; S. 1-35 The paper describes a novel way to support conceptual design in civil engineering. The designer uses semantical tools guaranteeing certain internal structures of the design result but also the fulfillment of various constraints. Two different approaches and corresponding tools are discussed: (a) Visually specified tools with automatic code generation to determine a design structure as well as fixing various constraints a design has to obey. These tools are also valuable for design knowledge specialist. (b) Extensions of existing CAD tools to provide semantical knowledge to be used by an architect. It is sketched how these different tools can be combined in the future. The main part of the paper discusses the concepts and realization of two prototypes following the two above approaches. The paper especially discusses that specific graphs and the specification of their structure are useful for both tool realization projects.},
  subject      = {CAD},
  language  = {en}
}
@inproceedings{SchoeningAbdelghani2009,
  author    = {Sch{\"o}ning, Michael Josef and Abdelghani, Adnane},
  title     = {Advancements in Nanotechnology and Microelectronics (ANM '09) <2009, Tunisia>: Proceedings book ; Tunisia, November, 13 \& 14, 2009 / Humboldt Kolleg. Ed. by Michael J. Sch{\"o}ning ; Adnane Abdelghani},
  organization    = {Humboldt-Kolleg Advancements in Nanotechnology and Microelectronics (ANM '09) <2009, Tunisia>},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-3113},
  year      = {2009},
  abstract  = {The ANM'09 multi-disciplinary scientific program includes topics in the fields of "Nanotechnology and Microelectronics" ranging from "Bio/Micro/Nano Materials and Interfacing" aspects, "Chemical and Bio-Sensors", "Magnetic and Superconducting Devices", "MEMS and Microfluidics" over "Theoretical Aspects, Methods and Modelling" up to the important bridging "Academics meet Industry".},
  subject      = {Nanopartikel},
  language  = {en}
}
@inproceedings{BallmannRaatschenStaat1985,
  author    = {Ballmann, J. and Raatschen, Hans-J{\"u}rgen and Staat, Manfred},
  title     = {High stress intensities in focussing zones of waves},
  doi       = {10.1016/B978-0-444-42520-1.50015-3},
  year      = {1985},
  abstract  = {The propagation of mechanical waves in plates of isotropic elastic material is investigated. After a short introduction to the understanding of focussing of stress waves in a plate with a curved boundary the method of characteristics is applied to a plate of hyperelastic material. Using this method the propagation of acceleration waves is discussed. Based on this a numerical difference scheme is developed for solving initial-boundary-value problems and applied to two examples: propagation of a point disturbance in a homogeneously finitely strained non-linear elastic plate and geometrical focussing in al linear elastic plate.},
  subject      = {Technische Mechanik},
  language  = {en}
}
@inproceedings{KernDikta2009,
  author    = {Kern, Alexander and Dikta, Gerhard},
  title     = {Probability of damage of electrical and electronic systems due to indirect lightning flashes - investigation of data from German insurance companies},
  year      = {2009},
  abstract  = {In the presented paper data collected from the field related to damage statistics of electrical and electronic apparatus in household are reported and investigated. These damages (total number approx. 74000 cases), registered by five German insurance companies in 2005 and 2006, were adviced by customers as caused by lightning overvoltages. With the use of stochastical methods it is possible, to reasses the collected data and to distinguish between cases, which are with high probability caused by lightning overvoltages, and those, which are not. If there was an indication for a direct strike, this case was excluded, so the focus was only on indirect lightning flashes, i.e. only flashes to ground near the structure and flashes to or nearby an incoming service line were investigated. The data from the field contain the location of damaged apparatus (residence of the policy holder) and the distances of the nearest cloud-to-ground stroke to the location of the damage registered by the German lightning location network BLIDS at the date of damage. The statistical data along with some complementary numerical simulations allow to verify the correspondence of the Standards rules used for IEC 62305-2 with the field data and to define some correction needs. The results could lead to a better understanding whether a damage reported to an insurance company is really caused by indirect lightning, or not.},
  subject      = {Blitzschutz},
  language  = {en}
}
@inproceedings{StaatTranPham2008,
  author    = {Staat, Manfred and Tran, Thanh Ngoc and Pham, Phu Tinh},
  title     = {Limit and shakedown reliability analysis by nonlinear programming},
  year      = {2008},
  abstract  = {7th International Conference on Reliability of Materials and Structures (RELMAS 2008). June 17 - 20, 2008 ; Saint Petersburg, Russia. pp 354-358. Reprint with corrections in red Introduction Analysis of advanced structures working under extreme heavy loading such as nuclear power plants and piping system should take into account the randomness of loading, geometrical and material parameters. The existing reliability are restricted mostly to the elastic working regime, e.g. allowable local stresses. Development of the limit and shakedown reliability-based analysis and design methods, exploiting potential of the shakedown working regime, is highly needed. In this paper the application of a new algorithm of probabilistic limit and shakedown analysis for shell structures is presented, in which the loading and strength of the material as well as the thickness of the shell are considered as random variables. The reliability analysis problems may be efficiently solved by using a system combining the available FE codes, a deterministic limit and shakedown analysis, and the First and Second Order Reliability Methods (FORM/SORM). Non-linear sensitivity analyses are obtained directly from the solution of the deterministic problem without extra computational costs.},
  subject      = {Finite-Elemente-Methode},
  language  = {en}
}
@inproceedings{TranPhamStaat2008,
  author    = {Tran, Thanh Ngoc and Pham, Phu Tinh and Staat, Manfred},
  title     = {Reliability analysis of shells based on direct plasticity methods},
  year      = {2008},
  abstract  = {Abstracts der CD-Rom Proceedings of the 8th World Congress on Computational Mechanics (WCCM8) and 5th Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008) 30.06. - 04.07.2008 Venedig, Italien. 2 Seiten Zusammenfassung der Autoren mit graph. Darst. und Literaturverzeichnis},
  subject      = {Finite-Elemente-Methode},
  language  = {en}
}
@inproceedings{StaatHeitzer1997,
  author    = {Staat, Manfred and Heitzer, Michael},
  title     = {Limit and shakedown analysis for plastic design},
  year      = {1997},
  abstract  = {Limit and shakedown theorems are exact theories of classical plasticity for the direct computation of safety factors or of the load carrying capacity under constant and varying loads. Simple versions of limit and shakedown analysis are the basis of all design codes for pressure vessels and pipings. Using Finite Element Methods more realistic modeling can be used for a more rational design. The methods can be extended to yield optimum plastic design. In this paper we present a first implementation in FE of limit and shakedown analyses for perfectly plastic material. Limit and shakedown analyses are done of a pipe-junction and a interaction diagram is calculated. The results are in good correspondence with the analytic solution we give in the appendix.},
  subject      = {Einspielen <Werkstoff>},
  language  = {en}
}
@inproceedings{HeitzerStaat2000,
  author    = {Heitzer, M. and Staat, Manfred},
  title     = {Direct FEM approach to design-by-analysis of pressurized components},
  year      = {2000},
  abstract  = {Abstracts of the ACHEMA 2000 - International Meeting on Chemical Engineering, Environmental Protection and Biotechnology, May 22 - 27, 2000. Frankfurt am Main. Achema 2000 : special edition / Linde. [Ed.: Linde AG. Red.: Volker R. Leski]. - Wiesbaden : Linde AG, 2000. - 56 p. : Ill., . - pp: 79 - 81},
  subject      = {Finite-Elemente-Methode},
  language  = {en}
}
@inproceedings{TranStaatKreissig2007,
  author    = {Tran, Thanh Ngoc and Staat, Manfred and Kreißig, R.},
  title     = {Finite element shakedown and limit reliability analysis of thin shells},
  year      = {2007},
  abstract  = {A procedure for the evaluation of the failure probability of elastic-plastic thin shell structures is presented. The procedure involves a deterministic limit and shakedown analysis for each probabilistic iteration which is based on the kinematical approach and the use the exact Ilyushin yield surface. Based on a direct definition of the limit state function, the non-linear problems may be efficiently solved by using the First and Second Order Reliabiblity Methods (Form/SORM). This direct approach reduces considerably the necessary knowledge of uncertain technological input data, computing costs and the numerical error. In: Computational plasticity / ed. by Eugenio Onate. Dordrecht: Springer 2007. VII, 265 S. (Computational Methods in Applied Sciences ; 7) (COMPLAS IX. Part 1 . International Center for Numerical Methods in Engineering (CIMNE)). ISBN 978-1-402-06576-7 S. 186-189},
  subject      = {Finite-Elemente-Methode},
  language  = {en}
}
@inproceedings{TranStaatKreissig2007,
  author    = {Tran, Thanh Ngoc and Staat, Manfred and Kreißig, R.},
  title     = {Calculation of load carrying capacity of shell structures with elasto-plastic material by direct methods},
  year      = {2007},
  abstract  = {Proceedings of the International Conference on Material Theory and Nonlinear Dynamics. MatDyn. Hanoi, Vietnam, Sept. 24-26, 2007, 8 p. In this paper, a method is introduced to determine the limit load of general shells using the finite element method. The method is based on an upper bound limit and shakedown analysis with elastic-perfectly plastic material model. A non-linear constrained optimisation problem is solved by using Newton's method in conjunction with a penalty method and the Lagrangean dual method. Numerical investigation of a pipe bend subjected to bending moments proves the effectiveness of the algorithm.},
  subject      = {Finite-Elemente-Methode},
  language  = {en}
}
@inproceedings{StaatBallmann1989,
  author    = {Staat, Manfred and Ballmann, J.},
  title     = {Fundamental aspects of numerical methods for the propagation of multi-dimensional nonlinear waves in solids},
  series = {Nonlinear hyperbolic equations : theory, computations methods, and applications ; proceedings of the 2nd International Conference on Nonlinear Hyperbolic Problems, Aachen},
  booktitle = {Nonlinear hyperbolic equations : theory, computations methods, and applications ; proceedings of the 2nd International Conference on Nonlinear Hyperbolic Problems, Aachen},
  pages     = {574 -- 588},
  year      = {1989},
  abstract  = {The nonlinear scalar constitutive equations of gases lead to a change in sound speed from point to point as would be found in linear inhomogeneous (and time dependent) media. The nonlinear tensor constitutive equations of solids introduce the additional local effect of solution dependent anisotropy. The speed of a wave passing through a point changes with propagation direction and its rays are inclined to the front. It is an open question whether the widely used operator splitting techniques achieve a dimensional splitting with physically reasonable results for these multi-dimensional problems. May be this is the main reason why the theoretical and numerical investigations of multi-dimensional wave propagation in nonlinear solids are so far behind gas dynamics. We hope to promote the subject a little by a discussion of some fundamental aspects of the solution of the equations of nonlinear elastodynamics. We use methods of characteristics because they only integrate mathematically exact equations which have a direct physical interpretation.},
  subject      = {Nichtlineare Welle},
  language  = {en}
}
@inproceedings{Staat2006,
  author    = {Staat, Manfred},
  title     = {Problems and chances for probabilistic fracture mechanics in the analysis of steel pressure boundary reliability. - {\"U}berarb. Ausg.},
  year      = {2006},
  abstract  = {In: Technical feasibility and reliability of passive safety systems for nuclear power plants. Proceedings of an Advisory Group Meeting held in J{\"u}lich, 21-24 November 1994. - Vienna , 1996. - Seite: 43 - 55 IAEA-TECDOC-920 Abstract: It is shown that the difficulty for probabilistic fracture mechanics (PFM) is the general problem of the high reliability of a small population. There is no way around the problem as yet. Therefore what PFM can contribute to the reliability of steel pressure boundaries is demon­strated with the example of a typical reactor pressure vessel and critically discussed. Although no method is distinguishable that could give exact failure probabilities, PFM has several addi­tional chances. Upper limits for failure probability may be obtained together with trends for design and operating conditions. Further, PFM can identify the most sensitive parameters, improved control of which would increase reliability. Thus PFM should play a vital role in the analysis of steel pressure boundaries despite all shortcomings.},
  subject      = {Bruchmechanik},
  language  = {en}
}
@misc{StaatBarry2006,
  author    = {Staat, Manfred and Barry, Steve},
  title     = {Continuum Mechanics with an Introduction to the Finite Element Method / Steve Barry; Manfred Staat. With extensions by Manfred Staat.},
  year      = {2006},
  abstract  = {Contents: 1 Introduction 2 One Dimensional Continuum Mechanics 3 Tensors 4 Three Dimensional Stress and Strain 5 Conservation Laws 6 Contiunuum Modelling 7 Plain Problems 8 Questions 9 Reference Information},
  subject      = {Technische Mechanik},
  language  = {en}
}
@misc{Staat2006,
  author    = {Staat, Manfred},
  title     = {Engineering Mechanics. Lecture Notes. 2nd edition, translation of the 3rd corrected and extended German edition of "Technische Mechanik"},
  year      = {2006},
  abstract  = {English translation of the corrected lectures notes of Sebastian Kr{\"a}mer. Contents 0 Introduction to Mechanics 1 Statics of Rigid Bodies 2 Elastostatics (Strength of Materials) 3 Kinematics 4 Kinetics Literature},
  subject      = {Technische Mechanik},
  language  = {en}
}
@inproceedings{LeiMulchandaniChenetal.2006,
  author    = {Lei, Yu and Mulchandani, Priti and Chen, Wilfred and Mulchandani, Ashok},
  title     = {Biosensor for direct determination of fenitrothion and EPN using recombinant Pseudomonas putida JS444 with surface expressed organophosphorus hydrolase. 1. modified clark oxygen electrode},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-1573},
  year      = {2006},
  abstract  = {This paper reports a first microbial biosensor for rapid and cost-effective determination of organophosphorus pesticides fenitrothion and EPN. The biosensor consisted of recombinant PNP-degrading/oxidizing bacteria Pseudomonas putida JS444 anchoring and displaying organophosphorus hydrolase (OPH) on its cell surface as biological sensing element and a dissolved oxygen electrode as the transducer. Surfaceexpressed OPH catalyzed the hydrolysis of fenitrothion and EPN to release 3-methyl-4-nitrophenol and p-nitrophenol, respectively, which were oxidized by the enzymatic machinery of Pseudomonas putida JS444 to carbon dioxide while consuming oxygen, which was measured and correlated to the concentration of organophosphates. Under the optimum operating conditions, the biosensor was able to measure as low as 277 ppb of fenitrothion and 1.6 ppm of EPN without interference from phenolic compounds and other commonly used pesticides such as carbamate pesticides, triazine herbicides and organophosphate pesticides without nitrophenyl substituent. The applicability of the biosensor to lake water was also demonstrated.},
  subject      = {Biosensor},
  language  = {en}
}
@inproceedings{BaronasIvanauskasKulys2006,
  author    = {Baronas, Romas and Ivanauskas, Feliksas and Kulys, Juozas},
  title     = {Mathematical modeling of biosensors based on an array of enzyme microreactors},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-1569},
  year      = {2006},
  abstract  = {This paper presents a two-dimensional-in-space mathematical model of biosensors based on an array of enzyme microreactors immobilised on a single electrode. The modeling system acts under amperometric conditions. The microreactors were modeled by particles and by strips. The model is based on the diffusion equations containing a nonlinear term related to the Michaelis-Menten kinetics of the enzymatic reaction. The model involves three regions: an array of enzyme microreactors where enzyme reaction as well as mass transport by diffusion takes place, a diffusion limiting region where only the diffusion takes place, and a convective region, where the analyte concentration is maintained constant. Using computer simulation, the influence of the geometry of the microreactors and of the diffusion region on the biosensor response was investigated. The digital simulation was carried out using the finite difference technique.},
  subject      = {Biosensor},
  language  = {en}
}
@inproceedings{BarekFischerNavratiletal.2006,
  author    = {Barek, Jiri and Fischer, Jan and Navratil, Tomas and Peckova, Karolina and Yosypchuk, Bogdan},
  title     = {Silver solid amalgam electrodes as sensors for chemical carcinogens},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-1554},
  year      = {2006},
  abstract  = {The applicability of differential pulse voltammetry (DPV) and adsorptive stripping voltammetry (AdSV) at a non-toxic meniscus-modified silver solid amalgam electrode (m-AgSAE) for the determination of trace amounts of genotoxic substances was demonstrated on the determination of micromolar and submicromolar concentrations of 3-nitrofluoranthene using methanol - 0.01 mol L-1 NaOH (9:1) mixture as a base electrolyte and of Ostazine Orange using 0.01 mol L-1 NaOH as a base electrolyte.},
  subject      = {Biosensor},
  language  = {en}
}
@inproceedings{AridaKloockSchoening2006,
  author    = {Arida, Hassan A. and Kloock, Joachim P. and Sch{\"o}ning, Michael Josef},
  title     = {Novel organic membrane-based thin-film microsensors for the determination of heavy metal cations},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-1545},
  year      = {2006},
  abstract  = {A first step towards the fabrication and electrochemical evaluation of thin-film microsensors based on organic PVC membranes for the determination of Hg(II), Cd(II), Pb(II) and Cu(II) ions in solutions has been realised. The membrane-coating mixture used in the preparation of this new type of microsensors is incorporating PVC as supporting matrix, o-nitrophenyloctylether (o-NPOE) as solvent mediator and a recently synthesized Hg[dimethylglyoxime(phene)]2+ and Bis-(4-hydroxyacetophenone)-ethylenediamine as electroactive materials for Hg(II) and Cd(II), respectively. A set of three commercialised ionophores for Cd(II), Pb(II) and Cu(II) has been also used for comparison. Thin-film microsensors based on these membranes showed a Nernstian response of slope (26-30 mV/dec.) for the respective tested cations. The potentiometric response characteristics (linear range, pH range, detection limit and response time) are comparable with those obtained by conventional membranes as well as coated wire electrodes prepared from the same membrane. The realisation of the new organic membrane-based thin-film microsensors overcomes the problem of an insufficient selectivity of solid-state-based thinfilm sensors.},
  subject      = {Biosensor},
  language  = {en}
}
@inproceedings{PijanowskaRemiszewska2006,
  author    = {Pijanowska, Dorota G. and Remiszewska, Elzbieta},
  title     = {pH-based detection of phenylalnine by potentiometric and colorimetric methods},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-1536},
  year      = {2006},
  abstract  = {In this paper, methods of sample preparation for potentiometric measurement of phenylalanine are presented. Basing on the spectrophotometric measurements of phenylalanine, the concentrations of reagents of the enzymatic reaction (10 mM L-Phe, 0,4 mM NAD+, 2U L-PheDH) were determined. Then, the absorption spectrum of the reaction product, NADH, was monitored (maximum peak at 340 nm). The results obtained by the spectrophotometric method were compared with the results obtained by the colourimetry, using pH indicators. The above-mentioned two methods will be used as references for potentiometric measurements of phenylalanine concentration.},
  subject      = {Biosensor},
  language  = {en}
}
@inproceedings{KatzWillner2006,
  author    = {Katz, Eugenii and Willner, Itamar},
  title     = {Magneto-controlled quantized electron transfer to surface-confined redox units and metal nanoparticles},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-1528},
  year      = {2006},
  abstract  = {Hydrophobic magnetic nanoparticles (NPs) consisting of undecanoate-capped magnetite (Fe3O4, average diameter ca. 5 nm) are used to control quantized electron transfer to surface-confined redox units and metal NPs. A two-phase system consisting of an aqueous electrolyte solution and a toluene phase that includes the suspended undecanoatecapped magnetic NPs is used to control the interfacial properties of the electrode surface. The attracted magnetic NPs form a hydrophobic layer on the electrode surface resulting in the change of the mechanisms of the surface-confined electrochemical processes. A quinone-monolayer modified Au electrode demonstrates an aqueous-type of the electrochemical process (2e-+2H+ redox mechanism) for the quinone units in the absence of the hydrophobic magnetic NPs, while the attraction of the magnetic NPs to the surface results in the stepwise single-electron transfer mechanism characteristic of a dry nonaqueous medium. Also, the attraction of the hydrophobic magnetic NPs to the Au electrode surface modified with Au NPs (ca. 1.4 nm) yields a microenvironment with a low dielectric constant that results in the single-electron quantum charging of the Au NPs.},
  subject      = {Biosensor},
  language  = {en}
}