@article{BiselliWandrey1988, author = {Biselli, Manfred and Wandrey, Christian}, title = {Reaction Mechanism of an Endoglucanase of Trichoderma Reesei QM 9414 using Cellodextrins as Substrate}, series = {Technology of biological processes, safety in biotechnology, applied genetic engineering : lectures held at the 5th DECHEMA Annual Meeting of Biotechnologists, May 12 - 13, 1987, [Frankfurt, Main] / [hrsg. von Dieter Behrens ...]}, journal = {Technology of biological processes, safety in biotechnology, applied genetic engineering : lectures held at the 5th DECHEMA Annual Meeting of Biotechnologists, May 12 - 13, 1987, [Frankfurt, Main] / [hrsg. von Dieter Behrens ...]}, publisher = {VCH}, address = {Weinheim}, pages = {425 -- 429}, year = {1988}, language = {en} } @article{BiselliVanderPolSpohnetal.1994, author = {Biselli, Manfred and Van der Pol, Jens J. and Spohn, Uwe and Eberhardt, Rolf}, title = {On-line monitoring of an animal cell culture with multi-channel flow injection analysis / van der Pol, Jens J.; Spohn, Uwe ; Eberhardt, Rolf ; G{\"a}tgens, Jochen ; Biselli, Manfred ; Wandrey, Christian ; Tramper, Johannes}, series = {Journal of Biotechnology. 37 (1994), H. 3}, journal = {Journal of Biotechnology. 37 (1994), H. 3}, isbn = {0168-1656}, pages = {253 -- 264}, year = {1994}, language = {en} } @article{BiselliVanderPolMachniketal.1997, author = {Biselli, Manfred and Van der Pol, Jens J. and Machnik, Marc and Portela-Klein, Theresa}, title = {On-line immunoanalysis of monoclonal antibodies during a continuous culture of hybridoma cells / Jens J. van der Pol, Marc Machnik, Manfred Biselli, Theresa Portela-Klein, Cornelis D. de Gooijer, Johannes Tramper und Christian Wandrey}, series = {Cytotechnology. 24 (1997), H. 1}, journal = {Cytotechnology. 24 (1997), H. 1}, isbn = {0920-9069}, pages = {19 -- 30}, year = {1997}, language = {en} } @article{BiselliVanderPolJokschetal.1995, author = {Biselli, Manfred and Van der Pol, Jens J. and Joksch, Burkhard and Galgens, Jochem}, title = {On-line control of an immobilized hybridoma culture with multi-channel flow injektion analysis / Jens J. van der Pol, Burkhard Joksch, Jochem Galgens, Manfred Biselli, Cornelis D. de Gooijer, Johannes Tramper and Christian Wandrey}, series = {Journal of Biotechnology. 43 (1995), H. 3}, journal = {Journal of Biotechnology. 43 (1995), H. 3}, isbn = {0168-1656}, pages = {229 -- 242}, year = {1995}, language = {en} } @article{BiselliVanderPolJokschetal.1994, author = {Biselli, Manfred and Van der Pol, Jens J. and Joksch, B. and Spohn, U.}, title = {On-line monitoring and control of glucose, glutamine, lactate and ammonium during a high-cell-density cultivation of hybridoma cells / van der Pol, Jens J. ; Joksch, B. ; Spohn, U. ; Biselli, M. ; Wandrey, C.}, series = {Proceedings of the sixth international meeting of the Japanese Association for Animal Cell Technology [JAACT 93]: Nagoya, Japan, November 9 - 12, 1993 / ed. by T. Kobayashi}, journal = {Proceedings of the sixth international meeting of the Japanese Association for Animal Cell Technology [JAACT 93]: Nagoya, Japan, November 9 - 12, 1993 / ed. by T. Kobayashi}, publisher = {Springer Netherland}, address = {Berlin}, isbn = {0-7923-3156-7}, pages = {167 -- 170}, year = {1994}, language = {en} } @article{BiselliVanderPolJokschetal.1992, author = {Biselli, Manfred and Van der Pol, Jens J. and Joksch, B. and Eberhardt, R.}, title = {Development of an enzymatic multichannel flow injection analysis system for monitoring mammalian cell fermentations / Van der Pol, J.J.; Joksch, B.; Eberhardt, R.; Biselli, M.; Wandrey, C., Tramper, J.}, series = {Biosensors : fundamentals, technologies and applications ; contributions to the BMFT status seminar with international participation May, 12 to 14, 1991, Internationales Bildungs-Centrum Bogensee/Brandenburg, Germany / org. by ZIM-Zentralinstitut f{\"u}r Molekularbiologie, Berlin-Buch and GBF, Braunschweig. Ed. by F. Scheller}, journal = {Biosensors : fundamentals, technologies and applications ; contributions to the BMFT status seminar with international participation May, 12 to 14, 1991, Internationales Bildungs-Centrum Bogensee/Brandenburg, Germany / org. by ZIM-Zentralinstitut f{\"u}r Molekularbiologie, Berlin-Buch and GBF, Braunschweig. Ed. by F. Scheller}, publisher = {VCH}, address = {Weinheim}, isbn = {3527284370}, pages = {349 -- 352}, year = {1992}, language = {en} } @article{BiselliVanderPolDeGooijeretal.1996, author = {Biselli, Manfred and Van der Pol, Jens J. and De Gooijer, Cornelis D. and Wandrey, Christian}, title = {Automation of selective assays for on-line bioprocess monitoring by flow-injection analysis / van der Pol, Jens J. ; de Gooijer, Cornelis D. ; Biselli, Manfred ; Wandrey, Christian ; Tramper, Johannes}, series = {Trends in Biotechnology. 14 (1996), H. 12}, journal = {Trends in Biotechnology. 14 (1996), H. 12}, isbn = {0167-7799}, pages = {471 -- 477}, year = {1996}, language = {en} } @article{BiselliThoemmesKulaetal.1994, author = {Biselli, Manfred and Th{\"o}mmes, J. and Kula, M.-R. and Wandrey, Christian}, title = {Batch kinetic data of hybridoma growth and productivity as a basis for the simulation of antibody production in various culture systems / Th{\"o}mmes, J. ; Biselli, M. ; Kula, M.-R. ; Wandrey, C.}, series = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier}, journal = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier}, publisher = {Butterworth-Heinemann}, address = {Oxford}, isbn = {0750618450}, pages = {513 -- 517}, year = {1994}, language = {en} } @article{BiselliThoemmesGaetgensetal.1993, author = {Biselli, Manfred and Th{\"o}mmes, J. and G{\"a}tgens, J. and Runstadler, P. W.}, title = {The influence of dissolved oxygen tension on the metabolic activity of an immobilized hybridoma population / Th{\"o}mmes, J. ; G{\"a}tgens, J. ; Biselli, M. ; Runstadler, P.W. ; Wandrey, C.}, series = {Cytotechnology . 13 (1993), H. 1}, journal = {Cytotechnology . 13 (1993), H. 1}, isbn = {0920-9069}, pages = {29 -- 39}, year = {1993}, language = {en} } @article{BiselliThoemmesGarskeetal.1992, author = {Biselli, Manfred and Th{\"o}mmes, J. and Garske, U. and Wandrey, Christian}, title = {Integrated detoxification: Reduction of ammonium concentration by dialysis with cation exchange membranes / Th{\"o}mmes, J. ; Garske, U. ; Biselli, M. ; Wandrey, C.}, series = {Animal cell technology : developments, processes, and products ; ESACT, European Society for Animal Cell Technology, the 11th meeting / Ed. R. E. Spier}, journal = {Animal cell technology : developments, processes, and products ; ESACT, European Society for Animal Cell Technology, the 11th meeting / Ed. R. E. Spier}, publisher = {Butterworth-Heinemann}, address = {Oxford}, isbn = {0750604212}, pages = {171 -- 175}, year = {1992}, language = {en} } @article{BiselliThoemmesBornetal.1995, author = {Biselli, Manfred and Th{\"o}mmes, J. and Born, C. and Wandrey, C.}, title = {Purification of monoclonal antibodies by fluidized bed adsorption / Th{\"o}mmes, J. ; Born, C. Biselli, M. ; Wandrey, C. ; Kula, M.-R.}, series = {Animal cell technology : developments towards the 21st century / edited by E. C. Beuvery}, journal = {Animal cell technology : developments towards the 21st century / edited by E. C. Beuvery}, publisher = {Kluwer Acad. Press}, address = {Dordrecht}, isbn = {0-7923-3736-0}, pages = {515 -- 519}, year = {1995}, language = {en} } @article{BiselliSchroederHerfurthetal.1997, author = {Biselli, Manfred and Schr{\"o}der, B. and Herfurth, C. and Schmoll, H.-J.}, title = {Cocultivation of hematopoietic cells in a fluidized bed reactor / Schr{\"o}der, B. ; Herfurth, C. ; Biselli, M. ; Schmoll, H.-J. ; Link, H. ; Ebell, W. ; Wandrey, C.}, series = {Animal cell technology : basic \& applied aspects : proceedings of the Eighth Annual Meeting of the Japanese Association for Animal Cell Technology, Iizuka, Fukuoka, Japan, November 6-10, 1995 / edited by K. Funatsu, Y. Shirai, and T. Matsushita}, journal = {Animal cell technology : basic \& applied aspects : proceedings of the Eighth Annual Meeting of the Japanese Association for Animal Cell Technology, Iizuka, Fukuoka, Japan, November 6-10, 1995 / edited by K. Funatsu, Y. Shirai, and T. Matsushita}, publisher = {Kluwer Acad. Press}, address = {Boston}, isbn = {0-7923-4486-3}, pages = {137 -- 141}, year = {1997}, language = {en} } @article{BiselliSchroederHerfurthetal.1997, author = {Biselli, Manfred and Schr{\"o}der, B. and Herfurth, C. and Meißner, P.}, title = {Differentiation of bone marrow cells immobilized on microcarriers in a fluidized bed reactor / Schr{\"o}der, B. ; Herfurth, C. ; Meißner, P. ; Biselli, M. ; Link, H. ; Wandrey, C.}, series = {Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo}, journal = {Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo}, publisher = {Kluwer}, address = {Dordrecht}, isbn = {0-7923-4321-2}, pages = {589 -- 593}, year = {1997}, language = {en} } @article{BiselliSchmidtBuechsetal.1999, author = {Biselli, Manfred and Schmidt, S. and B{\"u}chs, J. and Born, C.}, title = {A new correlation for the wall-to-fluid mass transfer in liquid-sol fluidized beds / Schmidt, S. ; B{\"u}chs, J. ; Born, C. ; Biselli, M.}, series = {Chemical Engineering Science. 54 (1999), H. 6}, journal = {Chemical Engineering Science. 54 (1999), H. 6}, isbn = {0009-2509}, pages = {829 -- 839}, year = {1999}, language = {en} } @article{BiselliSchmidWandrey1988, author = {Biselli, Manfred and Schmid, Georg and Wandrey, Christian}, title = {Preparation of cellodextrins and isolation of oligomeric side components and their characterization / Schmid, Georg ; Biselli, Manfred ; Wandrey, Christian}, series = {Analytical Biochemistry. 175 (1988)}, journal = {Analytical Biochemistry. 175 (1988)}, isbn = {0003-2697}, pages = {573 -- 583}, year = {1988}, language = {en} } @article{BiselliRolefDunkeretal.1994, author = {Biselli, Manfred and Rolef, G. and Dunker, R. and Wandrey, Christian}, title = {Optimization of antibody production in a fluidized bed bioreactor / Rolef, G. ; Biselli, M. ; Dunker, R. ; Wandrey, C.}, series = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier}, journal = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier}, publisher = {Butterworth-Heinemann}, address = {Oxford}, isbn = {0750618450}, pages = {481 -- 484}, year = {1994}, language = {en} } @article{BiselliRechmannFriedrichetal.2007, author = {Biselli, Manfred and Rechmann, Hanrik and Friedrich, Andrea and Forouzan, Dara}, title = {Characterization of photosynthetically active duckweed ( Wolffia australiana ) in vitro culture by Respiration Activity Monitoring System (RAMOS) / Henrik Rechmann, Andrea Friedrich, Dara Forouzan, Stefan Barth, Heide Schnabl, Manfred Biselli und Robert B}, series = {Biotechnology Letters. 29 (2007), H. 6}, journal = {Biotechnology Letters. 29 (2007), H. 6}, isbn = {0141-5492}, pages = {971 -- 977}, year = {2007}, language = {en} } @article{BiselliNollMuehlsiepenetal.2000, author = {Biselli, Manfred and Noll, Thomas and M{\"u}hlsiepen, Heinz and Engels, Ralf}, title = {A cell-culture reactor for the on-line evaluation of radiopharmaceuticals : evaluation of the lumped constant of FDG in human glioma cells / Noll, Thomas ; M{\"u}hlensiepen, Heinz ; Engels, Ralf ; Hamacher, Kurt ; Papaspyrou, Manfred ; Langen, Karl-Josef ; Bi}, series = {Journal of Nuclear Medicine. 41 (2000), H. 3}, journal = {Journal of Nuclear Medicine. 41 (2000), H. 3}, isbn = {0022-3123}, pages = {556 -- 564}, year = {2000}, language = {en} } @article{BiselliNollJelineketal.2002, author = {Biselli, Manfred and Noll, Thomas and Jelinek, Nanni and Schmidt, Sebastian}, title = {Cultivation of Hematopoietic Stem and Progenitor Cells: biochemical Engineering Aspects / Thomas Noll, Nanni Jelinek, Sebastian Schmidt, Manfred Biselli und Christian Wandrey}, series = {Tools and Applications of Biochemical Engineering Science}, journal = {Tools and Applications of Biochemical Engineering Science}, publisher = {Springer}, address = {Berlin}, isbn = {3-540-42250-1}, pages = {111 -- 128}, year = {2002}, language = {en} } @article{BiselliNollEisenkraetzeretal.2002, author = {Biselli, Manfred and Noll, Thomas and Eisenkr{\"a}tzer, Detlef and Kiesewetter, Andr{\´e}}, title = {Improved product formation in high density Chinese hamster ovary cell cultures transfected at confluency / Thomas Noll, Detlef Eisenkr{\"a}tzer, Andr{\´e} Kiesewetter, Andr{\´e} Dinter, Steffen Zeng, Christian Wandrey, Manfred Biselli und Eric G. Berger}, series = {Biotechnology Letters. 24 (2002), H. 11}, journal = {Biotechnology Letters. 24 (2002), H. 11}, isbn = {0141-5492}, pages = {861 -- 866}, year = {2002}, language = {en} } @article{BiselliNollWandrey1996, author = {Biselli, Manfred and Noll, T. and Wandrey, C.}, title = {Wirbelschichtreaktor und Biomasse-Monitor : ein leistungsf{\"a}higes Fermenationssystem f{\"u}r S{\"a}ugerzellen / Noll, T. ; Biselli, M. ; Wandrey, C.}, series = {Biospektrum. 2 (1996), H. 1}, journal = {Biospektrum. 2 (1996), H. 1}, isbn = {0947-0867}, pages = {65 -- 67}, year = {1996}, language = {de} } @article{BiselliNollWandrey1997, author = {Biselli, Manfred and Noll, T. and Wandrey, C.}, title = {On-line biomass monitoring of immobilized hybridoma cells by dielectrical measurements / Noll, T. ; Biselli, M. ; Wandrey, C.}, series = {Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo}, journal = {Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo}, publisher = {Kluwer}, address = {Dordrecht}, isbn = {0-7923-4321-2}, pages = {289 -- 294}, year = {1997}, language = {en} } @article{BiselliNoll1998, author = {Biselli, Manfred and Noll, T.}, title = {Dielectric spectroscopy in the cultivation of suspended and immobilized hybridoma cells / Noll, T.; Biselli, M.}, series = {Journal of Biotechnology. 63 (1998), H. 3}, journal = {Journal of Biotechnology. 63 (1998), H. 3}, isbn = {0168-1656}, pages = {187 -- 198}, year = {1998}, language = {en} } @article{BiselliMeissnerSchroederetal.1999, author = {Biselli, Manfred and Meissner, Petra and Schr{\"o}der, Bernd and Herfurth, Cornelia}, title = {Development of a fixed bed bioreactor for the expansion of human hematopoietic progenitor cells / Meissner, Petra ; Schr{\"o}der, Bernd ; Herfurth, Cornelia ; Biselli, Manfred}, series = {Cytotechnology. 30 (1999), H. 1}, journal = {Cytotechnology. 30 (1999), H. 1}, isbn = {0920-9069}, pages = {227 -- 234}, year = {1999}, language = {en} } @article{BiselliMachnikWandrey1996, author = {Biselli, Manfred and Machnik, M. and Wandrey, C.}, title = {Online-Immunoanalytik bei der kontinuierlichen Fermentation von Hybridomazellen / Machnik, M. ; Biselli, M. ; Wandrey, C.}, series = {BIO WORLD. 1 (1996), H. 3}, journal = {BIO WORLD. 1 (1996), H. 3}, isbn = {1424-8514}, pages = {12 -- 15}, year = {1996}, language = {de} } @article{BiselliLuellauWandrey1994, author = {Biselli, Manfred and L{\"u}llau, E. and Wandrey, Christian}, title = {Growth and metabolism of CHO-cells in porous glass carriers / L{\"u}llau, E. ; Biselli, M. ; Wandrey, C.}, series = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier}, journal = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier}, publisher = {Butterworth-Heinemann}, address = {Oxford}, isbn = {0750618450}, pages = {252 -- 255}, year = {1994}, language = {en} } @article{BiselliLuellauDreisbachetal.1992, author = {Biselli, Manfred and L{\"u}llau, E. and Dreisbach, C. and Grogg, A.}, title = {Immobilization of animal cells on chemically modified siran carrier / L{\"u}llau, E. ; Dreisbach, C. ; Grogg, A. ; Biselli, M. ; Wandrey, C.}, series = {Animal cell technology : developments, processes, and products ; ESACT, European Society for Animal Cell Technology, the 11th meeting / Ed. R. E. Spier}, journal = {Animal cell technology : developments, processes, and products ; ESACT, European Society for Animal Cell Technology, the 11th meeting / Ed. R. E. Spier}, publisher = {Butterworth-Heinemann}, address = {Oxford}, isbn = {0750604212}, pages = {469 -- 475}, year = {1992}, language = {en} } @article{BiselliKraglWandrey2002, author = {Biselli, Manfred and Kragl, U. and Wandrey, C.}, title = {Reaction Engineering for Enzyme-Catalyzed Biotransformations}, series = {Enzyme catalysis in organic synthesis : a comprehensive handbook. Bd. 1. - 2., completely rev. and enl. ed. / ed. by Karlheinz Drauz.}, journal = {Enzyme catalysis in organic synthesis : a comprehensive handbook. Bd. 1. - 2., completely rev. and enl. ed. / ed. by Karlheinz Drauz.}, publisher = {Wiley-VCH}, address = {Weinheim}, isbn = {3-527-29949-1}, pages = {185 -- 257}, year = {2002}, language = {en} } @article{BiselliKraglWandrey1995, author = {Biselli, Manfred and Kragl, U. and Wandrey, C.}, title = {Reaction Engineering for Enzyme-Catalyzed Biotransformations}, series = {Enzyme catalysis in organic synthesis : a comprehensive handbook. Bd. 1. / ed. by Karlheinz Drauz.}, journal = {Enzyme catalysis in organic synthesis : a comprehensive handbook. Bd. 1. / ed. by Karlheinz Drauz.}, publisher = {Wiley-VCH}, address = {Weinheim}, isbn = {3-527-28479-6}, pages = {89 -- 155}, year = {1995}, language = {en} } @article{BiselliKlyushnichenkoRodenbrocketal.1998, author = {Biselli, Manfred and Klyushnichenko, Vadim and Rodenbrock, Anja and Th{\"o}mmes, J{\"o}rg}, title = {Analysis of Hybridoma Cell Culture Processes by SDS-Gel Capillary Electrophoresis and matrix-assisted laser desorption ionization-time-of-flight MS / Vadim Klyushnichenko, Anja Rodenbrock, J{\"o}rg Th{\"o}mmes, Maria-Regina Kula, Holger Heine, Manfred Biselli}, series = {Biotechnology and Applied Biochemistry. 27 (1998), H. 3}, journal = {Biotechnology and Applied Biochemistry. 27 (1998), H. 3}, isbn = {0885-4513}, pages = {181 -- 188}, year = {1998}, language = {en} } @article{BiselliJelinekSchmidtetal.2001, author = {Biselli, Manfred and Jelinek, N. and Schmidt, S. and Noll, T.}, title = {Bioreaktoren zur Kultivierung blutbildender Zellen / Jelinek, N. ; Schmidt, S. ; Noll, T. ; Biselli, M.}, series = {Bioforum. 24 (2001), H. 6}, journal = {Bioforum. 24 (2001), H. 6}, isbn = {0940-0079}, pages = {418 -- 419}, year = {2001}, language = {de} } @article{BiselliJelinekSchmidtetal.2001, author = {Biselli, Manfred and Jelinek, N. and Schmidt, S. and Hilbert, U.}, title = {Neue Bioreaktoren zur Kultivierung h{\"a}matopoetischer Zellen / Jelinek, N. ; Schmidt, S. ; Hilbert, U. ; Thoma, S. ; Biselli, M. ; Wandrey, C.}, series = {Chemie Ingenieur Technik. 73 (2001), H. 7}, journal = {Chemie Ingenieur Technik. 73 (2001), H. 7}, isbn = {0009-286X}, pages = {894 -- 898}, year = {2001}, language = {de} } @article{BiselliJelinekSchmidtetal.2002, author = {Biselli, Manfred and Jelinek, N. and Schmidt, S. and Hilbert, U.}, title = {Novel bioreactors for the ex vivo cultivation of hematopoietic cells / Jelinek, N. ; Schmidt, S. ; Hilbert, U. ; Thoma, S. ; Biselli, M. ; Wandrey, C.}, series = {Engineering in Life Sciences. 2 (2002), H. 1}, journal = {Engineering in Life Sciences. 2 (2002), H. 1}, isbn = {1618-0240}, pages = {15 -- 18}, year = {2002}, language = {en} } @article{BiselliHilbertJelineketal.2000, author = {Biselli, Manfred and Hilbert, Ulrike and Jelinek, Nanni and Schmidt, Sebastian}, title = {Biotechnologische Aspekte der Kultivierung humaner T-Lymphozyten / Hilbert, Ulrike ; Jelinek, Nanni ; Schmidt, Sebastian ; Biselli, Manfred}, series = {Chemie Ingenieur Technik. 72 (2000), H. 7}, journal = {Chemie Ingenieur Technik. 72 (2000), H. 7}, isbn = {1522-2640}, pages = {746 -- 750}, year = {2000}, language = {de} } @article{BiselliHilbertNoll2001, author = {Biselli, Manfred and Hilbert, U. and Noll, T.}, title = {Cultivation of Human HCMV Specific Lymphocytes - An Example for Adoptive Immunotherapy / Hilbert, U. ; Biselli, M. ; Noll, T.}, series = {Animal cell technology : from target to market ; Tyl{\"o}sand, Sweden, June 10 - 14, 2001 / ed. by E. Lindner-Olsson ...}, journal = {Animal cell technology : from target to market ; Tyl{\"o}sand, Sweden, June 10 - 14, 2001 / ed. by E. Lindner-Olsson ...}, publisher = {Kluwer}, address = {Dordrecht}, isbn = {1-4020-0264-5}, pages = {558 -- 561}, year = {2001}, language = {en} } @article{BiselliHilbertJelineketal.2001, author = {Biselli, Manfred and Hilbert, U. and Jelinek, N. and Schmidt, S.}, title = {Bioprocess development for the cultivation of human T-lymphocytes / Hilbert, U. ; Jelinek, N. Schmidt, S. ; Biselli, M.}, series = {Engineering in Life Sciences. 1 (2001)}, journal = {Engineering in Life Sciences. 1 (2001)}, isbn = {1618-0240}, pages = {20 -- 23}, year = {2001}, language = {en} } @article{BiselliHambachRunstadleretal.1992, author = {Biselli, Manfred and Hambach, B. and Runstadler, P. W. and Wandrey, Christian}, title = {Development of a reactor-integrated aeration system for cultivation of animal cells in fluidized beds / Hambach, B. ; Biselli, M. ; Runstadler, P.W. ; Wandrey, C.}, series = {Animal cell technology : developments, processes, and products ; ESACT, European Society for Animal Cell Technology, the 11th meeting / Ed. R. E. Spier}, journal = {Animal cell technology : developments, processes, and products ; ESACT, European Society for Animal Cell Technology, the 11th meeting / Ed. R. E. Spier}, publisher = {Butterworth-Heinemann}, address = {Oxford}, isbn = {0750604212}, pages = {381 -- 385}, year = {1992}, language = {en} } @article{BiselliBaeckerPoghossianetal.2010, author = {Biselli, Manfred and B{\"a}cker, Matthias and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Schnitzler, Thomas and Zang, Werner and Wagner, P.}, title = {Entwicklung eines modularen festk{\"o}rperbasierten Sensorsystems f{\"u}r die {\"U}berwachung von Zellkulturfermenationen}, series = {Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vortr{\"a}ge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in N{\"u}rnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)}, journal = {Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vortr{\"a}ge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in N{\"u}rnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)}, publisher = {VDE Verlag}, address = {Berlin}, isbn = {978-3-8007-3260-9}, pages = {688 -- 691}, year = {2010}, language = {de} } @article{BiselliBornWandrey1995, author = {Biselli, Manfred and Born, C. and Wandrey, C.}, title = {Production of monoclonal antibodies in a pilot scale fluidized bed bioreactor / Born, C.; Biselli, M.; Wandrey, C.}, series = {Animal cell technology : developments towards the 21st century / edited by E. C. Beuvery}, journal = {Animal cell technology : developments towards the 21st century / edited by E. C. Beuvery}, publisher = {Kluwer Acad. Press}, address = {Dordrecht}, isbn = {0-7923-3736-0}, pages = {515 -- 519}, year = {1995}, language = {en} } @article{BiselliBornWandrey1995, author = {Biselli, Manfred and Born, C. and Wandrey, C.}, title = {Oxygen transfer from the gasphase to the immobilized cells in membrane aerated fluidized beds / Born, C. ; Biselli, M. ; Wandrey, C.}, series = {Animal cell technology : basic \& applied aspects : proceedings of the Eighth Annual Meeting of the Japanese Association for Animal Cell Technology, Iizuka, Fukuoka, Japan, November 6-10, 1995 / edited by K. Funatsu, Y. Shirai, and T. Matsushita}, journal = {Animal cell technology : basic \& applied aspects : proceedings of the Eighth Annual Meeting of the Japanese Association for Animal Cell Technology, Iizuka, Fukuoka, Japan, November 6-10, 1995 / edited by K. Funatsu, Y. Shirai, and T. Matsushita}, publisher = {Kluwer Acad. Press}, address = {Boston}, isbn = {0-7923-4486-3}, pages = {83 -- 87}, year = {1995}, language = {en} } @article{BiselliBornThoemmesetal.1996, author = {Biselli, Manfred and Born, C. and Th{\"o}mmes, J. and Wandrey, C.}, title = {An approach to integrated antibody production: Coupling of fluidized bed cultivation and fluidized bed adsorption / Born, C. ; Th{\"o}mmes, J. ; Biselli, M. ; Wandrey, C. ; Kula, M.-R.}, series = {Bioprocess Engineering. 15 (1996), H. 1}, journal = {Bioprocess Engineering. 15 (1996), H. 1}, isbn = {1615-7591}, pages = {21 -- 29}, year = {1996}, language = {en} } @article{BerndtZahn1975, author = {Berndt, Heinz and Zahn, Helmut}, title = {Peptide, 99 : Monomere cyclische Cystinpeptidderivate, III ; Synthese der Schafinsulin-A-Kettensequenzen A2-21 und A1-21 als monomere cyclische Dicystinpeptidderivate}, series = {Justus Liebigs Annalen der Chemie}, volume = {1975}, journal = {Justus Liebigs Annalen der Chemie}, number = {9}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1099-0690}, doi = {10.1002/jlac.197519750908}, pages = {1601 -- 1612}, year = {1975}, abstract = {Die Synthese der Sequenzen A2—21 (13) und A1—21 (15) der Schafinsulin-A-Kette als monomere cyclische Dicystinpeptidderivate wird beschrieben. Die intrachenaren Cystinbr{\"u}cken A6—7 und A 11 —20 vermitteln die L{\"o}slichkeit dieser Derivate in Dimethylformamid und erm{\"o}glichen erstmalig die Reindarstellung vollgesch{\"u}tzter Insulin-A-Kettenderivate. Die w{\"a}hrend der Synthese eingesetzten Schutzgruppen lassen sich mittels Trifluoressigs{\"a}ure und 2-Mercapto{\"a}thanol quantitativ entfernen.}, language = {de} } @article{BerndtKrueger1985, author = {Berndt, Heinz and Kr{\"u}ger, G{\"o}tz}, title = {Resolution of enantiomeric amino acid derivatives by high-performance liquid chromatography on chiral stationary phases}, series = {Journal of chromatography A}, volume = {1985}, journal = {Journal of chromatography A}, number = {348}, issn = {0021-9673}, doi = {10.1016/S0021-9673(01)92461-6}, pages = {275 -- 279}, year = {1985}, language = {en} } @article{BerndtKlostermeyerZahn1972, author = {Berndt, Heinz and Klostermeyer, Henning and Zahn, Helmut}, title = {Zur Synthese monomerer cyclischer Cystinpeptidderivate, I : Synthese der Sequenz A 6-9 des Schafinsulins als Cyclocystinylderivat}, series = {Justus Liebigs Annalen der Chemie}, volume = {759}, journal = {Justus Liebigs Annalen der Chemie}, number = {1}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1099-0690}, doi = {10.1002/jlac.19727590109}, pages = {114 -- 120}, year = {1972}, abstract = {Es wird die Synthese der Sequenz A 6-9 des Schafinsulins in der gesch{\"u}tzten Form Boc-Cys-Cys-Ala-Gly-OBuᵗ (5) sowie das Verhalten dieses monomeren cyclischen Cystinpeptidderivates gegen{\"u}ber den in der Peptidchemie gebr{\"a}uchlichen Reagenzien Bortrifluorid/Eisessig, Tri{\"a}thylamin und Hydrazinhydrat beschrieben.}, language = {de} } @article{BerndtGattnerZahn1975, author = {Berndt, Heinz and Gattner, Hans-Gregor and Zahn, Helmut}, title = {Semisynthetisches Des-A1-glycin-Schafinsulin}, series = {Biological Chemistry}, volume = {356}, journal = {Biological Chemistry}, number = {2}, publisher = {De Gruyter}, address = {Berlin}, issn = {1437-4315}, doi = {10.1515/bchm2.1975.356.2.1455}, pages = {1469 -- 1472}, year = {1975}, language = {de} } @article{Berndt1979, author = {Berndt, Heinz}, title = {Synthese der Sequenz 71—86 des Humanproinsulins, I : Synthese der Sequenz 71—86 als monomeres cyclisches Biscystinpeptidderivat und als Tetra-S-tritylderivat}, series = {Hoppe-Seyler's Zeitschrift f{\"u}r physiologische Chemie}, volume = {360}, journal = {Hoppe-Seyler's Zeitschrift f{\"u}r physiologische Chemie}, number = {1}, issn = {1437-4315}, doi = {10.1515/bchm2.1979.360.1.747}, pages = {747 -- 760}, year = {1979}, language = {de} } @article{Berndt1979, author = {Berndt, Heinz}, title = {Synthese der Sequenz 71—86 des Humanproinsulins, III : Synthese {\"u}ber die Fragmente 71—78 und 79—86}, series = {Hoppe-Seyler's Zeitschrift f{\"u}r physiologische Chemie}, volume = {360}, journal = {Hoppe-Seyler's Zeitschrift f{\"u}r physiologische Chemie}, number = {1}, issn = {1437-4315}, doi = {10.1515/bchm2.1979.360.1.765}, pages = {765 -- 772}, year = {1979}, language = {de} } @article{Berndt1980, author = {Berndt, Heinz}, title = {Zur Reaktion von Iminodithiocarbonaten mit Carbons{\"a}uren. I : Synthese des Modellpeptid-Derivates Z-(L)-Ala-(L/D)-Phe-(L)-Val-OMe}, series = {Tetrahedron letters}, volume = {21}, journal = {Tetrahedron letters}, number = {34}, issn = {0040-4039}, doi = {10.1016/S0040-4039(00)78663-1}, pages = {3265 -- 3268}, year = {1980}, language = {de} } @article{BergsMonakhovaDiehletal.2021, author = {Bergs, Michel and Monakhova, Yulia and Diehl, Bernd W. and Konow, Christopher and V{\"o}lkering, Georg and Pude, Ralf and Schulze, Margit}, title = {Lignins isolated via catalyst-free organosolv pulping from Miscanthus x giganteus, M. sinensis, M. robustus and M. nagara: a comparative study}, series = {Molecules}, volume = {26}, journal = {Molecules}, number = {4}, publisher = {MDPI}, address = {Basel}, issn = {1420-3049}, doi = {10.3390/molecules26040842}, year = {2021}, abstract = {As a low-input crop, Miscanthus offers numerous advantages that, in addition to agricultural applications, permits its exploitation for energy, fuel, and material production. Depending on the Miscanthus genotype, season, and harvest time as well as plant component (leaf versus stem), correlations between structure and properties of the corresponding isolated lignins differ. Here, a comparative study is presented between lignins isolated from M. x giganteus, M. sinensis, M. robustus and M. nagara using a catalyst-free organosolv pulping process. The lignins from different plant constituents are also compared regarding their similarities and differences regarding monolignol ratio and important linkages. Results showed that the plant genotype has the weakest influence on monolignol content and interunit linkages. In contrast, structural differences are more significant among lignins of different harvest time and/or season. Analyses were performed using fast and simple methods such as nuclear magnetic resonance (NMR) spectroscopy. Data was assigned to four different linkages (A: β-O-4 linkage, B: phenylcoumaran, C: resinol, D: β-unsaturated ester). In conclusion, A content is particularly high in leaf-derived lignins at just under 70\% and significantly lower in stem and mixture lignins at around 60\% and almost 65\%. The second most common linkage pattern is D in all isolated lignins, the proportion of which is also strongly dependent on the crop portion. Both stem and mixture lignins, have a relatively high share of approximately 20\% or more (maximum is M. sinensis Sin2 with over 30\%). In the leaf-derived lignins, the proportions are significantly lower on average. Stem samples should be chosen if the highest possible lignin content is desired, specifically from the M. x giganteus genotype, which revealed lignin contents up to 27\%. Due to the better frost resistance and higher stem stability, M. nagara offers some advantages compared to M. x giganteus. Miscanthus crops are shown to be very attractive lignocellulose feedstock (LCF) for second generation biorefineries and lignin generation in Europe.}, language = {en} } @article{BechtSchollmayerMonakhovaetal.2021, author = {Becht, Alexander and Schollmayer, Curd and Monakhova, Yulia and Holzgrabe, Ulrike}, title = {Tracing the origin of paracetamol tablets by near-infrared, mid-infrared, and nuclear magnetic resonance spectroscopy using principal component analysis and linear discriminant analysis}, series = {Analytical and Bioanalytical Chemistry}, volume = {413}, journal = {Analytical and Bioanalytical Chemistry}, publisher = {Springer Nature}, issn = {1618-2650}, doi = {10.1007/s00216-021-03249-z}, pages = {3107 -- 3118}, year = {2021}, abstract = {Most drugs are no longer produced in their own countries by the pharmaceutical companies, but by contract manufacturers or at manufacturing sites in countries that can produce more cheaply. This not only makes it difficult to trace them back but also leaves room for criminal organizations to fake them unnoticed. For these reasons, it is becoming increasingly difficult to determine the exact origin of drugs. The goal of this work was to investigate how exactly this is possible by using different spectroscopic methods like nuclear magnetic resonance and near- and mid-infrared spectroscopy in combination with multivariate data analysis. As an example, 56 out of 64 different paracetamol preparations, collected from 19 countries around the world, were chosen to investigate whether it is possible to determine the pharmaceutical company, manufacturing site, or country of origin. By means of suitable pre-processing of the spectra and the different information contained in each method, principal component analysis was able to evaluate manufacturing relationships between individual companies and to differentiate between production sites or formulations. Linear discriminant analysis showed different results depending on the spectral method and purpose. For all spectroscopic methods, it was found that the classification of the preparations to their manufacturer achieves better results than the classification to their pharmaceutical company. The best results were obtained with nuclear magnetic resonance and near-infrared data, with 94.6\%/99.6\% and 98.7/100\% of the spectra of the preparations correctly assigned to their pharmaceutical company or manufacturer.}, language = {en} }