@article{KetelhutGoellBraunsteinetal.2018, author = {Ketelhut, Maike and G{\"o}ll, Fabian and Braunstein, Bj{\"o}rn and Albracht, Kirsten and Abel, Dirk}, title = {Comparison of different training algorithms for the leg extension training with an industrial robot}, series = {Current Directions in Biomedical Engineering}, volume = {4}, journal = {Current Directions in Biomedical Engineering}, number = {1}, publisher = {De Gruyter}, address = {Berlin}, issn = {2364-5504}, doi = {10.1515/cdbme-2018-0005}, pages = {17 -- 20}, year = {2018}, abstract = {In the past, different training scenarios have been developed and implemented on robotic research platforms, but no systematic analysis and comparison have been done so far. This paper deals with the comparison of an isokinematic (motion with constant velocity) and an isotonic (motion against constant weight) training algorithm. Both algorithms are designed for a robotic research platform consisting of a 3D force plate and a high payload industrial robot, which allows leg extension training with arbitrary six-dimensional motion trajectories. In the isokinematic as well as the isotonic training algorithm, individual paths are defined i n C artesian s pace by sufficient s upport p oses. I n t he i sotonic t raining s cenario, the trajectory is adapted to the measured force as the robot should only move along the trajectory as long as the force applied by the user exceeds a minimum threshold. In the isotonic training scenario however, the robot's acceleration is a function of the force applied by the user. To validate these findings, a simulative experiment with a simple linear trajectory is performed. For this purpose, the same force path is applied in both training scenarios. The results illustrate that the algorithms differ in the force dependent trajectory adaption.}, language = {en} } @article{FunkeBeckmannKeinzetal.2018, author = {Funke, Harald and Beckmann, Nils and Keinz, Jan and Abanteriba, Sylvester}, title = {Comparison of Numerical Combustion Models for Hydrogen and Hydrogen-Rich Syngas Applied for Dry-Low-Nox-Micromix-Combustion}, series = {Journal of Engineering for Gas Turbines and Power}, volume = {140}, journal = {Journal of Engineering for Gas Turbines and Power}, number = {8}, publisher = {ASME}, address = {New York, NY}, issn = {0742-4795}, doi = {10.1115/1.4038882}, pages = {9 Seiten}, year = {2018}, abstract = {The Dry-Low-NOx (DLN) Micromix combustion technology has been developed as low emission combustion principle for industrial gas turbines fueled with hydrogen or syngas. The combustion process is based on the phenomenon of jet-in-crossflow-mixing (JICF). Fuel is injected perpendicular into the air-cross-flow and burned in a multitude of miniaturized, diffusion-like flames. The miniaturization of the flames leads to a significant reduction of NOx emissions due to the very short residence time of reactants in the flame. In the Micromix research approach, computational fluid dynamics (CFD) analyses are validated toward experimental results. The combination of numerical and experimental methods allows an efficient design and optimization of DLN Micromix combustors concerning combustion stability and low NOx emissions. The paper presents a comparison of several numerical combustion models for hydrogen and hydrogen-rich syngas. They differ in the complexity of the underlying reaction mechanism and the associated computational effort. The performance of a hybrid eddy-break-up (EBU) model with a one-step global reaction is compared to a complex chemistry model and a flamelet generated manifolds (FGM) model, both using detailed reaction schemes for hydrogen or syngas combustion. Validation of numerical results is based on exhaust gas compositions available from experimental investigation on DLN Micromix combustors. The conducted evaluation confirms that the applied detailed combustion mechanisms are able to predict the general physics of the DLN-Micromix combustion process accurately. The FGM method proved to be generally suitable to reduce the computational effort while maintaining the accuracy of detailed chemistry.}, language = {en} } @incollection{BhattaraiFrotscherStaat2018, author = {Bhattarai, Aroj and Frotscher, Ralf and Staat, Manfred}, title = {Computational Analysis of Pelvic Floor Dysfunction}, series = {Women's Health and Biomechanics}, booktitle = {Women's Health and Biomechanics}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-71574-2}, doi = {10.1007/978-3-319-71574-2_17}, pages = {217 -- 230}, year = {2018}, abstract = {Pelvic floor dysfunction (PFD) is characterized by the failure of the levator ani (LA) muscle to maintain the pelvic hiatus, resulting in the descent of the pelvic organs below the pubococcygeal line. This chapter adopts the modified Humphrey material model to consider the effect of the muscle fiber on passive stretching of the LA muscle. The deformation of the LA muscle subjected to intra-abdominal pressure during Valsalva maneuver is compared with the magnetic resonance imaging (MRI) examination of a nulliparous female. Numerical result shows that the fiber-based Humphrey model simulates the muscle behavior better than isotropic constitutive models. Greater posterior movement of the LA muscle widens the levator hiatus due to lack of support from the anococcygeal ligament and the perineal structure as a consequence of birth-related injury and aging. Old and multiparous females with uncontrolled urogenital and rectal hiatus tend to develop PFDs such as prolapse and incontinence.}, language = {en} } @article{BhattaraiStaat2018, author = {Bhattarai, Aroj and Staat, Manfred}, title = {Computational comparison of different textile implants to correct apical prolapse in females}, series = {Current Directions in Biomedical Engineering}, volume = {4}, journal = {Current Directions in Biomedical Engineering}, number = {1}, publisher = {De Gruyter}, address = {Berlin}, doi = {10.1515/cdbme-2018-0159}, pages = {661 -- 664}, year = {2018}, abstract = {Prosthetic textile implants of different shapes, sizes and polymers are used to correct the apical prolapse after hysterectomy (removal of the uterus). The selection of the implant before or during minimally invasive surgery depends on the patient's anatomical defect, intended function after reconstruction and most importantly the surgeon's preference. Weakness or damage of the supporting tissues during childbirth, menopause or previous pelvic surgeries may put females in higher risk of prolapse. Numerical simulations of reconstructed pelvic floor with weakened tissues and organ supported by textile product models: DynaMesh®-PRS soft, DynaMesh®-PRP soft and DynaMesh®-CESA from FEG Textiletechnik mbH, Germany are compared.}, language = {en} } @phdthesis{Bhattarai2018, author = {Bhattarai, Aroj}, title = {Constitutive modeling of female pelvic floor dysfunctions and reconstructive surgeries using prosthetic mesh implants}, isbn = {978-3-9818074-8-6}, doi = {10.17185/duepublico/70340}, pages = {192 S.}, year = {2018}, language = {en} } @inproceedings{HofmannMatareSchifferetal.2018, author = {Hofmann, Till and Matar{\´e}, Victor and Schiffer, Stefan and Ferrein, Alexander and Lakemeyer, Gerhard}, title = {Constraint-based online transformation of abstract plans into executable robot actions}, series = {Proceedings of the 2018 AAAI Spring Symposium on Integrating Representation, Reasoning, Learning, and Execution for Goal Directed Autonomy}, booktitle = {Proceedings of the 2018 AAAI Spring Symposium on Integrating Representation, Reasoning, Learning, and Execution for Goal Directed Autonomy}, pages = {549 -- 553}, year = {2018}, language = {en} } @inproceedings{SchmidtsKraftSchreiberetal.2018, author = {Schmidts, Oliver and Kraft, Bodo and Schreiber, Marc and Z{\"u}ndorf, Albert}, title = {Continuously evaluated research projects in collaborative decoupled environments}, series = {2018 ACM/IEEE 5th International Workshop on Software Engineering Research and Industrial PracticePractice, May 29, 2018, Gothenburg, Sweden : SER\&IP' 18}, booktitle = {2018 ACM/IEEE 5th International Workshop on Software Engineering Research and Industrial PracticePractice, May 29, 2018, Gothenburg, Sweden : SER\&IP' 18}, publisher = {ACM}, address = {New York, NY}, pages = {1 -- 9}, year = {2018}, abstract = {Often, research results from collaboration projects are not transferred into productive environments even though approaches are proven to work in demonstration prototypes. These demonstration prototypes are usually too fragile and error-prone to be transferred easily into productive environments. A lot of additional work is required. Inspired by the idea of an incremental delivery process, we introduce an architecture pattern, which combines the approach of Metrics Driven Research Collaboration with microservices for the ease of integration. It enables keeping track of project goals over the course of the collaboration while every party may focus on their expert skills: researchers may focus on complex algorithms, practitioners may focus on their business goals. Through the simplified integration (intermediate) research results can be introduced into a productive environment which enables getting an early user feedback and allows for the early evaluation of different approaches. The practitioners' business model benefits throughout the full project duration.}, language = {en} } @article{JungStaatMueller2018, author = {Jung, Alexander and Staat, Manfred and M{\"u}ller, Wolfram}, title = {Corrigendum to "Flight style optimization in ski jumping on normal, large, and ski flying hills" [J. Biomech 47 (2014) 716-722]}, series = {Journals of Biomechanics}, journal = {Journals of Biomechanics}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0021-9290}, doi = {10.1016/j.jbiomech.2018.02.001}, pages = {313}, year = {2018}, language = {en} } @inproceedings{JockwerKleiberUibel2018, author = {Jockwer, R. and Kleiber, M. and Uibel, Thomas}, title = {Criteria for Evaluating the Simplification of Design Rules for Dowel-type Fasteners}, series = {International Network on Timber Engineering Research, INTER : proceedings, meeting 51, 10 - 13 August 2016, Tallinn, Estonia}, booktitle = {International Network on Timber Engineering Research, INTER : proceedings, meeting 51, 10 - 13 August 2016, Tallinn, Estonia}, editor = {G{\"o}rlacher, Rainer}, publisher = {Timber Scientific Publishing, KIT Holzbau und Baukonstruktionen}, address = {Karlsruhe}, pages = {461 -- 466}, year = {2018}, language = {en} } @inproceedings{AlhwarinFerreinScholl2018, author = {Alhwarin, Faraj and Ferrein, Alexander and Scholl, Ingrid}, title = {CRVM: Circular Random Variable-based Matcher - A Novel Hashing Method for Fast NN Search in High-dimensional Spaces}, series = {Proceedings of the 7th International Conference on Pattern Recognition Applications and Methods, ICPRAM 2018}, booktitle = {Proceedings of the 7th International Conference on Pattern Recognition Applications and Methods, ICPRAM 2018}, isbn = {978-989-758-276-9}, doi = {10.5220/0006692802140221}, pages = {214 -- 221}, year = {2018}, language = {en} } @inproceedings{KoenigWolf2018, author = {K{\"o}nig, Johannes Alexander and Wolf, Martin R.}, title = {Cybersecurity awareness training provided by the competence developing game GHOST}, series = {ACHI 2018 : The Eleventh International Conference on Advances in Computer-Human Interactions}, booktitle = {ACHI 2018 : The Eleventh International Conference on Advances in Computer-Human Interactions}, isbn = {978-1-61208-616-3}, pages = {81 -- 87}, year = {2018}, abstract = {This paper introduces a Competence Developing Game (CDG) for the purpose of a cybersecurity awareness training for businesses. The target audience will be discussed in detail to understand their requirements. It will be explained why and how a mix of business simulation and serious game meets these stakeholder requirements. It will be shown that a tablet and touchscreen based approach is the most suitable solution. In addition, an empirical study will be briefly presented. The study was carried out to examine how an interaction system for a 3D-tablet based CDG has to be designed, to be manageable for non-game experienced employees. Furthermore, it will be explained which serious content is necessary for a Cybersecurity awareness training CDG and how this content is wrapped in the game}, language = {en} } @inproceedings{ButenwegMarinkovic2018, author = {Butenweg, Christoph and Marinkovic, Marko}, title = {Damage reduction system for masonry infill walls under seismic loading}, series = {ce/papers}, volume = {2}, booktitle = {ce/papers}, number = {4}, publisher = {Ernst \& Sohn Verlag}, address = {Berlin}, doi = {10.1002/cepa.863}, pages = {267 -- 273}, year = {2018}, abstract = {Reinforced concrete (RC) frames with masonry infills are frequently used in seismic regions all over the world. Generally masonry infills are considered as nonstructural elements and thus are typically neglected in the design process. However, the observations made after strong earthquakes have shown that masonry infills can modify the dynamic behavior of the structure significantly. The consequences were total collapses of buildings and loss of human lives. This paper presents the new system INODIS (Innovative Decoupled Infill System) developed within the European research project INSYSME (Innovative Systems for Earthquake Resistant Masonry Enclosures in RC Buildings). INODIS decouples the frame and the masonry infill by means of special U-shaped rubbers placed in between frame and infill. The effectiveness of the system was investigated by means of full scale tests on RC frames with masonry infills subjected to in-plane and out-of-plane loading. Furthermore small specimen tests were conducted to determine material characteristics of the components and the resistances of the connections. Finally, a micromodel was developed to simulate the in-plane behavior of RC frames infilled with AAC blocks with and without installation of the INODIS system.}, language = {en} } @article{Golland2018, author = {Golland, Alexander}, title = {Das Kopplungsverbot in der Datenschutz-Grundverordnung Anwendungsbereich, {\"o}konomische Auswirkungen auf Web 2.0-Dienste und L{\"o}sungsvorschlag}, series = {MMR Multimedia und Recht}, volume = {21}, journal = {MMR Multimedia und Recht}, number = {3}, publisher = {Beck}, address = {M{\"u}nchen}, isbn = {1434-596X}, pages = {130 -- 135}, year = {2018}, abstract = {Das Kopplungsverbot fristete - obwohl in rechtswissenschaftlicher Literatur seit jeher diskutiert - unter der Geltung des BDSG ein Schattendasein. Mit der Datenschutz-Grundverordnung (DS-GVO) ist eine {\"A}nderung absehbar: Der neue Art. EWG_DSGVO Artikel 7 Abs. EWG_DSGVO Artikel 7 Absatz 4 DS-GVO stellt klar, dass die Leistungserbringung nicht von der Einwilligungserteilung abh{\"a}ngig gemacht werden darf. Doch dieses scheinbare Novum des Datenschutzrechts wirft zahlreiche Fragen auf. W{\"a}hrend vor allem Vertreter der unternehmerischen Praxis die Anwendung des Kopplungsverbots in zahlreichen Konstellationen ablehnen, beschw{\"o}ren dessen Apologeten das Ende s{\"a}mtlicher „datenfinanzierten" Dienste herauf. Der vorliegende Beitrag gibt Einblick in die Regelungstiefe einer Norm, die das Web 2.0 revolutionieren k{\"o}nnte, und schl{\"a}gt eine L{\"o}sung vor, die dem Schutz der Privatsph{\"a}re des Betroffenen und den wirtschaftlichen Interessen von Diensteanbietern gleichermaßen gerecht wird.}, language = {de} } @article{Golland2018, author = {Golland, Alexander}, title = {Das neue kirchliche Datenschutzrecht - Herausforderungen f{\"u}r Unternehmen der Privatwirtschaft}, series = {DSB Datenschutz-Berater}, volume = {42}, journal = {DSB Datenschutz-Berater}, number = {9}, publisher = {dfv Mediengruppe}, address = {Frankfurt a.M.}, isbn = {0170-7256}, pages = {179 -- 181}, year = {2018}, language = {de} } @article{Olbertz2018, author = {Olbertz, Klaus}, title = {Das rechtssichere Arbeitszeugnis - Erlaubte und nicht erlaubte Formulierungen und anderes Wissenswertes}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {12}, publisher = {NWB-Verl.}, address = {Herne}, issn = {1860-9449}, pages = {802 -- 813}, year = {2018}, language = {de} } @article{Olbertz2018, author = {Olbertz, Klaus}, title = {Der Interimsmanager als Selbst{\"a}ndiger oder Arbeitnehmer : Vertragliche Varianten des Interimsmanagements im Faktencheck}, series = {NWB - Steuer- und Wirtschaftsrecht}, journal = {NWB - Steuer- und Wirtschaftsrecht}, number = {31}, publisher = {NWB-Verl.}, address = {Herne}, issn = {1860-9449}, pages = {2260 -- 2266}, year = {2018}, language = {de} } @article{Golland2018, author = {Golland, Alexander}, title = {Der r{\"a}umliche Anwendungsbereich der DS-GVO}, series = {DuD Datenschutz und Datensicherheit}, volume = {42}, journal = {DuD Datenschutz und Datensicherheit}, number = {6}, publisher = {Springer}, address = {Heidelberg}, isbn = {1862-2607}, pages = {351 -- 357}, year = {2018}, abstract = {Die Datenschutz-Grundverordnung (DS-GVO) regelt in ihrem Art. 3 das r{\"a}umlich anwendbare Datenschutzrecht und zielt dabei gerade auch auf Angebote nichteurop{\"a}ischer Diensteanbieter ab. Die bisherige Diskussion konzentriert sich bislang in erster Linie darauf, das eingef{\"u}hrte Marktortprinzip zu thematisieren; das weitgehend unangetastete Niederlassungsprinzip und vor allem die Probleme, die sich durch dessen unver{\"a}nderte Beibehaltung ergeben, werden dagegen nicht er{\"o}rtert. Der folgende Beitrag versucht sich an einer systematischen Analyse eines teils kontrovers, teils kaum diskutierten Themas.}, language = {de} } @article{FissabreWilson2018, author = {Fissabre, Anke and Wilson, Ariane}, title = {Der Turm mit zehn Spornen - Ein in Monthoiron gebauter Entwurf von Leonardo Da Vinci?}, series = {In situ: Zeitschrift f{\"u}r Architekturgeschichte}, journal = {In situ: Zeitschrift f{\"u}r Architekturgeschichte}, number = {1}, publisher = {Wernersche Verlagsgesellschaft}, address = {Worms}, issn = {1866-959X}, pages = {65 -- 82}, year = {2018}, language = {de} } @book{Kurz2018, author = {Kurz, Melanie}, title = {Designstreit : exemplarische Kontroversen {\"u}ber Gestaltung}, publisher = {Wilhelm Fink}, address = {Paderborn}, isbn = {978-3-7705-6294-7 (Druckausgabe)}, pages = {304 Seiten}, year = {2018}, abstract = {Die Geschichte des Designs ist ges{\"a}umt von Auseinandersetzungen. Debattiert wird unter Berufsgenossen, in Interessensverb{\"a}nden, zwischen Wettbewerbern und nicht zuletzt an Hochschulen; als Foren dienen zum Beispiel Zeitungen, Konferenzen oder Gerichtss{\"a}le. Doch welche Gr{\"u}nde gibt es f{\"u}r Streit {\"u}ber Design? Die Kontroversen beschr{\"a}nken sich keineswegs auf die {\"A}sthetik von Artefakten. Auch haben wir es trotz der Vielfalt an Streitf{\"a}llen nicht mit einem un{\"u}berschaubaren Feld von zusammenhanglosen Einzelereignissen zu tun. Wie das vorliegende Buch anhand historischer Kontroversen zeigt, lassen sich im Bereich der Gestaltung Streitkategorien identifizieren. Die Diskursanalyse verr{\"a}t, dass sich die Konfliktursachen im Verlauf der Designhistorie kaum ver{\"a}ndern. So haben die angef{\"u}hrten Dispute erstaunliche {\"A}hnlichkeit mit aktuellen Debatten im Fach. Sie sind Lehrst{\"u}cke und k{\"o}nnen dazu anregen, eine Streitkultur im Design zu etablieren, die sich davon distanziert, den Meinungsgegner in ein politisches Lager zu ›verr{\"a}umen‹.}, language = {de} } @article{MolinnusHardtSiegertetal.2018, author = {Molinnus, Denise and Hardt, Gabriel and Siegert, Petra and Willenberg, Holger S. and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Detection of Adrenaline in Blood Plasma as Biomarker for Adrenal Venous Sampling}, series = {Electroanalysis}, volume = {30}, journal = {Electroanalysis}, number = {5}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1521-4109}, doi = {10.1002/elan.201800026}, pages = {937 -- 942}, year = {2018}, abstract = {An amperometric bi-enzyme biosensor based on substrate recycling principle for the amplification of the sensor signal has been developed for the detection of adrenaline in blood. Adrenaline can be used as biomarker verifying successful adrenal venous sampling procedure. The adrenaline biosensor has been realized via modification of a galvanic oxygen sensor with a bi-enzyme membrane combining a genetically modified laccase and a pyrroloquinoline quinone-dependent glucose dehydrogenase. The measurement conditions such as pH value and temperature were optimized to enhance the sensor performance. A high sensitivity and a low detection limit of about 0.5-1 nM adrenaline have been achieved in phosphate buffer at pH 7.4, relevant for measurements in blood samples. The sensitivity of the biosensor to other catecholamines such as noradrenaline, dopamine and dobutamine has been studied. Finally, the sensor has been successfully applied for the detection of adrenaline in human blood plasma.}, language = {en} } @article{BronderJessingPoghossianetal.2018, author = {Bronder, Thomas and Jessing, Max P. and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Detection of PCR-Amplified Tuberculosis DNA Fragments with Polyelectrolyte-Modified Field-Effect Sensors}, series = {Analytical Chemistry}, volume = {90}, journal = {Analytical Chemistry}, number = {12}, publisher = {ACS Publications}, address = {Washington, DC}, issn = {0003-2700}, doi = {10.1021/acs.analchem.8b01807}, pages = {7747 -- 7753}, year = {2018}, abstract = {Field-effect-based electrolyte-insulator-semiconductor (EIS) sensors were modified with a bilayer of positively charged weak polyelectrolyte (poly(allylamine hydrochloride) (PAH)) and probe single-stranded DNA (ssDNA) and are used for the detection of complementary single-stranded target DNA (cDNA) in different test solutions. The sensing mechanism is based on the detection of the intrinsic molecular charge of target cDNA molecules after the hybridization event between cDNA and immobilized probe ssDNA. The test solutions contain synthetic cDNA oligonucleotides (with a sequence of tuberculosis mycobacteria genome) or PCR-amplified DNA (which origins from a template DNA strand that has been extracted from Mycobacterium avium paratuberculosis-spiked human sputum samples), respectively. Sensor responses up to 41 mV have been measured for the test solutions with DNA, while only small signals of ∼5 mV were detected for solutions without DNA. The lower detection limit of the EIS sensors was ∼0.3 nM, and the sensitivity was ∼7.2 mV/decade. Fluorescence experiments using SybrGreen I fluorescence dye support the electrochemical results.}, language = {en} } @article{MolinnusMuschallikGonzalezetal.2018, author = {Molinnus, Denise and Muschallik, Lukas and Gonzalez, Laura Osorio and Bongaerts, Johannes and Wagner, Torsten and Selmer, Thorsten and Siegert, Petra and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Development and characterization of a field-effect biosensor for the detection of acetoin}, series = {Biosensors and Bioelectronics}, volume = {115}, journal = {Biosensors and Bioelectronics}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.bios.2018.05.023}, pages = {1 -- 6}, year = {2018}, abstract = {A capacitive electrolyte-insulator-semiconductor (EIS) field-effect biosensor for acetoin detection has been presented for the first time. The EIS sensor consists of a layer structure of Al/p-Si/SiO₂/Ta₂O₅/enzyme acetoin reductase. The enzyme, also referred to as butane-2,3-diol dehydrogenase from B. clausii DSM 8716T, has been recently characterized. The enzyme catalyzes the (R)-specific reduction of racemic acetoin to (R,R)- and meso-butane-2,3-diol, respectively. Two different enzyme immobilization strategies (cross-linking by using glutaraldehyde and adsorption) have been studied. Typical biosensor parameters such as optimal pH working range, sensitivity, hysteresis, linear concentration range and long-term stability have been examined by means of constant-capacitance (ConCap) mode measurements. Furthermore, preliminary experiments have been successfully carried out for the detection of acetoin in diluted white wine samples.}, language = {en} } @article{AboulnagaZouSelmeretal.2018, author = {Aboulnaga, Elhussiny A. and Zou, Huibin and Selmer, Thorsten and Xian, Mo}, title = {Development of a plasmid-based, tunable, tolC-derived expression system for application in Cupriavidus necator H16}, series = {Journal of Biotechnology}, volume = {274}, journal = {Journal of Biotechnology}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0168-1656}, doi = {10.1016/j.jbiotec.2018.03.007}, pages = {15 -- 27}, year = {2018}, abstract = {Cupriavidus necator H16 gains increasing attention in microbial research and biotechnological application due to its diverse metabolic features. Here we present a tightly controlled gene expression system for C. necator including the pBBR1-vector that contains hybrid promoters originating from C. necator native tolC-promoter in combination with a synthetic tetO-operator. The expression of the reporter gene from these plasmids relies on the addition of the exogenous inducer doxycycline (dc). The novel expression system offers a combination of advantageous features as; (i) high and dose-dependent recombinant protein production, (ii) tight control with a high dynamic range (On/Off ratio), which makes it applicable for harmful pathways or for toxic protein production, (iii) comparable cheap inducer (doxycycline, dc), (iv) effective at low inducer concentration, that makes it useful for large scale application, (v) rapid, diffusion controlled induction, and (vi) the inducer does not interfere within the cell metabolism. As applications of the expression system in C. necator H16, the growth ability on glycerol was enhanced by constitutively expressing the E. coli glpk gene-encoding for glycerol kinase. Likewise, we used the system to overcome the expression toxicity of mevalonate pathway in C. necator H16. With this system, the mevalonate-genes were successfully introduced in the host and the recombinant strains could produce about 200 mg/l mevalonate.}, language = {en} } @article{EdipSesovButenwegetal.2018, author = {Edip, K. and Sesov, V. and Butenweg, Christoph and Bojadjieva, J.}, title = {Development of coupled numerical model for simulation of multiphase soil}, series = {Computers and Geotechnics}, volume = {96}, journal = {Computers and Geotechnics}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0266-352X}, doi = {10.1016/j.compgeo.2017.08.016}, pages = {118 -- 131}, year = {2018}, abstract = {In this paper, a coupled multiphase model considering both non-linearities of water retention curves and solid state modeling is proposed. The solid displacements and the pressures of both water and air phases are unknowns of the proposed model. The finite element method is used to solve the governing differential equations. The proposed method is demonstrated through simulation of seepage test and partially consolidation problem. Then, implementation of the model is done by using hypoplasticity for the solid phase and analyzing the fully saturated triaxial experiments. In integration of the constitutive law error controlling is improved and comparisons done accordingly. In this work, the advantages and limitations of the numerical model are discussed.}, language = {en} } @inproceedings{MilkovaRosinButenwegetal.2018, author = {Milkova, Kristina and Rosin, Julia and Butenweg, Christoph and Dumova-Jovanoska, Elena}, title = {Development of Seismic Vulnerability Curves for Region Specific Masonry Buildings}, series = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018}, booktitle = {16th European Conference on Earthquake Engineering, Thessaloniki, 18-21 June, 2018}, pages = {1 -- 10}, year = {2018}, language = {en} } @article{Fissabre2018, author = {Fissabre, Anke}, title = {Die Relevanz der historischen Bauforschung f{\"u}r neue Impulse in Stadtplanung und Architektur. Das Beispiel der Chiesa della SS. Maria Incoronata und des Servitenklosters in Sabbioneta.}, series = {archimaera}, journal = {archimaera}, number = {Nr. 7, Juli 2018}, publisher = {Archimaera}, address = {Aachen}, issn = {1865-7001}, url = {http://nbn-resolving.de/urn:nbn:de:0009-21-47067}, pages = {99 -- 105}, year = {2018}, abstract = {Durch die Bauforschung im Rahmen des mehrj{\"a}hrigen Projektes "Die Hochkorridore von Sabbioneta" konnten der Verlauf und viele Anschl{\"u}sse der hochliegenden G{\"a}nge an bestehende Bauten weitgehend gekl{\"a}rt werden. Im Bereich der Chiesa della SS. Maria Incoronata und des angrenzenden Servitenklosters f{\"u}hrten die Bauuntersuchungen zu v{\"o}llig neuen Erkenntnissen {\"u}ber den ehemaligen Verlauf des Hochkorridors und damit zu einer Neuinterpretation des baulichen Ensembles sowie seiner Bedeutung f{\"u}r die Idealstadt. Aus dieser historischen Umdeutung entstanden Ideen f{\"u}r die Umnutzung des ehemaligen Servitenklosters und seiner angrenzenden Freifl{\"a}chen, die im Rahmen von studentischen Entw{\"u}rfen am Lehrstuhl f{\"u}r Baugeschichte und Denkmalpflege in Kooperation mit dem Lehrstuhl f{\"u}r Landschaftsarchitektur der RWTH Aachen weiterentwickelt wurden. Somit stellten sich Befunde einer historisch orientierten Bauforschung mit {\"u}bergeordneter Fragestellung als neue Impulsgeber f{\"u}r Stadtplanung, Architektur und Denkmalpflege heraus.}, language = {de} } @incollection{Finkenberger2018, author = {Finkenberger, Isabel Maria}, title = {Die Stadt als st{\"a}dtisch-theatrale Versuchsanordnung: Wie wollen wir in Zukunft leben und welche Stadt brauchen wir daf{\"u}r?}, series = {Un/Certain Futures - Rollen des Designs in gesellschaftlichen Transformationsprozessen}, booktitle = {Un/Certain Futures - Rollen des Designs in gesellschaftlichen Transformationsprozessen}, publisher = {transcript}, address = {Bielefeld}, isbn = {9783839443323}, doi = {https://doi.org/10.1515/9783839443323-009}, pages = {86 -- 95}, year = {2018}, language = {de} } @article{JochimMenzel2018, author = {Jochim, Haldor E. and Menzel, Christoph J.}, title = {Die Trassenb{\"u}ndelung als Planungsmethode nachhaltiger Verkehrspolitik}, series = {Der Eisenbahningenieur : EI}, volume = {69}, journal = {Der Eisenbahningenieur : EI}, number = {11}, publisher = {DVV Media Group}, address = {Hamburg}, issn = {0013-2810}, pages = {26 -- 31}, year = {2018}, language = {de} } @inproceedings{Pieper2018, author = {Pieper, Martin}, title = {Digitale Hochschullehre in mathematischen und mathematikdidaktischen Veranstaltungen}, series = {Beitr{\"a}ge zum Mathematikunterricht 2018 : Vortr{\"a}ge zur Mathematikdidaktik und zur Schnittstelle Mathematik/Mathematikdidaktik auf der gemeinsamen Jahrestagung GDM und DMV 2018 (52. Jahrestagung der Gesellschaft f{\"u}r Didaktik der Mathematik). Bd. 1}, booktitle = {Beitr{\"a}ge zum Mathematikunterricht 2018 : Vortr{\"a}ge zur Mathematikdidaktik und zur Schnittstelle Mathematik/Mathematikdidaktik auf der gemeinsamen Jahrestagung GDM und DMV 2018 (52. Jahrestagung der Gesellschaft f{\"u}r Didaktik der Mathematik). Bd. 1}, publisher = {WTM-Verlag}, address = {M{\"u}nster}, isbn = {978-3-95987-089-4}, pages = {105 -- 106}, year = {2018}, language = {de} } @misc{OPUS4-8740, title = {Dimensionen 1-2018: Magazin der FH Aachen University of Applied Sciences - Grenzg{\"a}nge}, organization = {FH Aachen, University of Applied Sciences}, pages = {62 Seiten}, year = {2018}, abstract = {Grenzg{\"a}nge: Op j{\"o}ck in Vaals mit Peter Sparla Inhaltsverzeichnis 6 "Mr. Vaals": Ein Spaziergang mit Peter Sparla durch die niederl{\"a}ndische Gemeinde 14 Ein Verein hebt ab: Von der Theorie in die Praxis: Die Flugtechnische Arbeitsgemeinschaft will Studierende f{\"u}rs Fliegen begeistern 18 Vom Flugplatzkind zur Ingenieurin: Sarah Hamacher hat Luft- und Raumfahrt studiert und arbeitet jetzt bei der ADAC-Luftfahrttechnik 20 Mit Sonne im Tank durch das australische Outback: FH-Student Enno D{\"u}lberg berichtet von der World Solar Challenge 24 Es steckt mehr dahinter: Eine Eschweiler Firma entwickelt Elektronik-L{\"o}sungen f{\"u}r Anh{\"a}ngerkupplungen - mit Unterst{\"u}tzung der FH Aachen 27 Von Mekn{\`e}s nach J{\"u}lich: Die Geschichte von Rabab Azizi 28 Das blaue Wunder neu erleben: Aachener Tuchtradition soll wieder in Mode kommen 32 Es werde Licht: Markus van Hauten macht spektakul{\"a}re Landschaftsfotos 36 Maschinenbau von morgen: Dr. Julia Kessler forscht zu additiv gefertigten Leichtbaustrukturen 39 Vier Siebenen und eine Eins: Kopfnuss 40 Auf Tuchf{\"u}hlung mit der Praxis: Das ausbildungsintegrierende Studium ist anspruchsvoll und fordernd. Aber es bietet den Studierenden und Unternehmen auch viel. 44 Eine große B{\"u}hne f{\"u}r die Forschung: FH aachen pr{\"a}sentiert das Spektrum ihrer wissenschaftlichen Arbeit 46 Eine Erfolgsstory: Das Institut f{\"u}r Nano- und Biotechnologien feiert sein 10-j{\"a}hriges Jubil{\"a}um 49 Das Ingenieurstudium fr{\"u}her und heute: Der Verein "Ingenieurfreunde der FH Aachen" blickt auf eine ereignisreiche Zeit zur{\"u}ck 50 Ist es ein Flugzeug? Ist es ein Multikopter: Nein es ist PhoenAix! Das Flugger{\"a}t soll Vorteile von Flugzeug- und Hubschraubertechnik kombinieren 54 G{\"u}terwagen der Zukunft: Im Studiengang Schienfahrzeugtechnik wird an intelligenten und hoch technisierten G{\"u}terwaggons gearbeitet 58 Wenn Gedanken Gestalt annehmen: Prof. Thomas T{\"u}nnemann zum Projekt Neo Forma 60 Vorhang auf f{\"u}r die Wissenschaft: Future-Lab-Gala im Theater Aachen 62 Impressum}, language = {de} } @misc{OPUS4-8741, title = {Dimensionen 2-2018: Magazin der FH Aachen University of Applied Sciences - Virtuelle Realit{\"a}ten}, address = {Aachen}, organization = {FH Aachen, University of Applied Sciences}, pages = {63 Seiten}, year = {2018}, abstract = {Virtuelle Realit{\"a}ten Inhaltsverzeichnis 6 Erweiterte Dimensionen: Special zum Thema Virtual Reality 10 "VR und AR werden unsere Welt durchdringen": Ein Interview zum Potenzial von Virtual und Augmented Reality 14 Lernen aus einem anderen Blickwinkel: VR wird in Studium und Lehre zunehmend angewandt 18 Parallele Realit{\"a}ten in der Forschung: Virtual und Augmented Reality in Forschungsprojekten 22 Willkommen in der Welt der M{\"o}glichkeiten: Wie real ist die Illusion der Realit{\"a}t 24 Eine z{\"u}ndende Idee: Institut f{\"u}r Mikrowellen- und Plasmatechnik (IMP) entwickelt neue Plasmaz{\"u}ndkerze f{\"u}r sparsamere Benzinmotoren 28 Der Elefant im Park: "WESTPARK story constructed": Studierende bauen skulpturales M{\"o}bel 30 Herr Bernoulli geht auf Reisen: Das "aero | race lab" bringt Experimente zur Luft- und Raumfahrt an die Schulen 32 Eine Auszeit vom Alltag: Martin Stockberg schafft Kunstwerke im Sand 36 Der Einer im urbanen Mobilit{\"a}tstetris: An der FH Aachen wird urbane Elektromobilit{\"a}t neu gedacht 39 Der Primzahlw{\"u}rfel: Kopfnuss 40 Schwarz Weiß Bunt: Die politische Kunst des FH-Absolventen Ralf Metzenmacher 44 Die Champions League des Schweißens: LaVa-X will das Laserstrahlschweißen im Vakuum etablieren 46 Auf der Suche nach dem goldenen Schnatz: St{\"o}cke statt Besen. Spielfeld statt Arena. In J{\"u}lich spielen Studierende Quidditch. 48 Bei ihm wird Science-Fiction zu Science-Fact: Volker Schmid erz{\"a}hlt von seiner Arbeit beim Deutschen Zentrum f{\"u}r Luft- und Raumfahrt (DLR) 52 Die Ideenschmieden: Junge Menschen aus aller Welt diskutieren bei den Summerschools {\"u}ber Zukunftsthemen 56 Forschung auf h{\"o}chstem Niveau: Dr. Jan Oberl{\"a}nder und Doktorand Dua {\"O}zsoylu stehen f{\"u}r das, was das Institut f{\"u}r Nano- und Biotechnologien auszeichnet 58 Der Dom und ich: Dompublikation und LEGO-Throne zum Jubil{\"a}um 40 Jahre UNESCO-Weltkulturerbe 62 Sag "Ja" zum Studium: Der neue kooperative Bachelorstudiengang "Elektrotechnik mit Orientierungssemester" 63 Impressum}, language = {de} } @inproceedings{TranMatthiesStavroulakisetal.2018, author = {Tran, Ngoc Trinh and Matthies, Hermann G. and Stavroulakis, Georgios Eleftherios and Staat, Manfred}, title = {Direct plastic structural design by chance constrained programming}, series = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, booktitle = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, pages = {12 Seiten}, year = {2018}, abstract = {We propose a stochastic programming method to analyse limit and shakedown of structures under random strength with lognormal distribution. In this investigation a dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit or the shakedown limit. The edge-based smoothed finite element method (ES-FEM) using three-node linear triangular elements is used.}, language = {en} } @inproceedings{SchollSuderSchiffer2018, author = {Scholl, Ingrid and Suder, Sebastian and Schiffer, Stefan}, title = {Direct Volume Rendering in Virtual Reality}, series = {Bildverarbeitung f{\"u}r die Medizin 2018}, booktitle = {Bildverarbeitung f{\"u}r die Medizin 2018}, publisher = {Springer Vieweg}, address = {Berlin}, isbn = {978-3-662-56537-7}, doi = {10.1007/978-3-662-56537-7_79}, pages = {297 -- 302}, year = {2018}, language = {en} } @article{HirschKleebergSchmitz2018, author = {Hirsch, Marko and Kleeberg, Jochen and Schmitz, Philipp}, title = {Dynamische Asset-Allocation- Strategien im Niedrigzinsumfeld}, series = {Absolut|report : neue Perspektiven f{\"u}r institutionelle Investoren}, journal = {Absolut|report : neue Perspektiven f{\"u}r institutionelle Investoren}, number = {6}, publisher = {Absolut Research}, address = {Hamburg}, pages = {52}, year = {2018}, language = {de} } @article{Wollert2018, author = {Wollert, J{\"o}rg}, title = {Echtzeit-Ethernet - Basis f{\"u}r Industrie 4.0}, series = {Design \& Elektronik}, journal = {Design \& Elektronik}, publisher = {WEKA-Fachmedien}, address = {M{\"u}nchen}, isbn = {0933-8667}, year = {2018}, language = {de} } @article{WerkhausenAlbrachtCroninetal.2018, author = {Werkhausen, Amelie and Albracht, Kirsten and Cronin, Neil J and Paulsen, G{\o}ran and Bojsen-M{\o}ller, Jens and Seynnes, Olivier R}, title = {Effect of training-induced changes in achilles tendon stiffness on muscle-tendon behavior during landing}, series = {Frontiers in physiology}, journal = {Frontiers in physiology}, number = {9}, publisher = {Frontiers Research Foundation}, address = {Lausanne}, issn = {1664-042X}, doi = {10.3389/fphys.2018.00794}, pages = {11 Seiten}, year = {2018}, abstract = {During rapid deceleration of the body, tendons buffer part of the elongation of the muscle-tendon unit (MTU), enabling safe energy dissipation via eccentric muscle contraction. Yet, the influence of changes in tendon stiffness within the physiological range upon these lengthening contractions is unknown. This study aimed to examine the effect of training-induced stiffening of the Achilles tendon on triceps surae muscle-tendon behavior during a landing task. Twenty-one male subjects were assigned to either a 10-week resistance-training program consisting of single-leg isometric plantarflexion (n = 11) or to a non-training control group (n = 10). Before and after the training period, plantarflexion force, peak Achilles tendon strain and stiffness were measured during isometric contractions, using a combination of dynamometry, ultrasound and kinematics data. Additionally, testing included a step-landing task, during which joint mechanics and lengths of gastrocnemius and soleus fascicles, Achilles tendon, and MTU were determined using synchronized ultrasound, kinematics and kinetics data collection. After training, plantarflexion strength and Achilles tendon stiffness increased (15 and 18\%, respectively), and tendon strain during landing remained similar. Likewise, lengthening and negative work produced by the gastrocnemius MTU did not change detectably. However, in the training group, gastrocnemius fascicle length was offset (8\%) to a longer length at touch down and, surprisingly, fascicle lengthening and velocity were reduced by 27 and 21\%, respectively. These changes were not observed for soleus fascicles when accounting for variation in task execution between tests. These results indicate that a training-induced increase in tendon stiffness does not noticeably affect the buffering action of the tendon when the MTU is rapidly stretched. Reductions in gastrocnemius fascicle lengthening and lengthening velocity during landing occurred independently from tendon strain. Future studies are required to provide insight into the mechanisms underpinning these observations and their influence on energy dissipation.}, language = {en} } @article{BaringhausGaigall2018, author = {Baringhaus, Ludwig and Gaigall, Daniel}, title = {Efficiency comparison of the Wilcoxon tests in paired and independent survey samples}, series = {Metrika}, volume = {2018}, journal = {Metrika}, number = {81}, publisher = {Springer}, address = {Berlin}, issn = {1435-926X}, doi = {10.1007/s00184-018-0661-4}, pages = {891 -- 930}, year = {2018}, abstract = {The efficiency concepts of Bahadur and Pitman are used to compare the Wilcoxon tests in paired and independent survey samples. A comparison through the length of corresponding confidence intervals is also done. Simple conditions characterizing the dominance of a procedure are derived. Statistical tests for checking these conditions are suggested and discussed.}, language = {de} } @inproceedings{GrundmannBauerBieleetal.2018, author = {Grundmann, Jan Thimo and Bauer, Waldemar and Biele, Jens and Boden, Ralf and Ceriotti, Matteo and Cordero, Federico and Dachwald, Bernd and Dumont, Etienne and Grimm, Christian and Herč{\´i}k, David and Herique, Alain and Ho, Tra-Mi and Jahnke, Rico and Koch, Aaron and Kofman, Wlodek and Koncz, Alexander and Krause, Christian and Lange, Caroline and Lichtenheldt, Roy and Maiwald, Volker and Mikschl, Tobias and Mikulz, Eugen and Montenegro, Sergio and Pelivan, Ivanka and Peloni, Alessandro and Plettemeier, Dirk and Quantius, Dominik and Reershemius, Siebo and Renger, Thomas and Riemann, Johannes and Ruffer, Michael and Sasaki, Kaname and Schmitz, Nicole and Seboldt, Wolfgang and Seefeldt, Patric and Spietz, Peter and Spr{\"o}witz, Tom and Sznajder, Maciej and Tardivel, Simon and Toth, Norbert and Wejmo, Elisabet and Wolff, Friederike and Ziach, Christian}, title = {Efficient massively parallel prospection for ISRU by multiple near-earth asteroid rendezvous using near-term solar sails and'now-term'small spacecraft solutions}, series = {2nd Asteroid Science Intersections with In-Space Mine Engineering - ASIME 2018}, booktitle = {2nd Asteroid Science Intersections with In-Space Mine Engineering - ASIME 2018}, pages = {1 -- 33}, year = {2018}, abstract = {Physical interaction with small solar system bodies (SSSB) is key for in-situ resource utilization (ISRU). The design of mining missions requires good understanding of SSSB properties, including composition, surface and interior structure, and thermal environment. But as the saying goes "If you've seen one asteroid, you've seen one Asteroid": Although some patterns may begin to appear, a stable and reliable scheme of SSSB classification still has to be evolved. Identified commonalities would enable generic ISRU technology and spacecraft design approaches with a high degree of re-use. Strategic approaches require much broader in-depth characterization of the SSSB populations of interest to the ISRU community. The DLR-ESTEC GOSSAMER Roadmap Science Working Groups identified target-flexible Multiple Near-Earth asteroid (NEA) Rendezvous (MNR) as one of the missions only feasible with solar sail propulsion, showed the ability to access any inclination and a wide range of heliocentric distances as well as continuous operation close to Earth's orbit where low delta-v objects reside.}, language = {en} } @incollection{GollandBaumHammingeretal.2018, author = {Golland, Alexander and Baum, Michael and Hamminger, Alexander and Olbertz, Klaus}, title = {Ein {\"U}berblick: Umsetzung der Datenschutz-Grundverordnung}, series = {Das neue Datenschutzrecht in der Praxis des Steuerberaters Beitragssammlung}, booktitle = {Das neue Datenschutzrecht in der Praxis des Steuerberaters Beitragssammlung}, publisher = {NWB Verlag}, address = {Herne}, isbn = {978-3-482-67271-2}, pages = {8 -- 14}, year = {2018}, abstract = {Datenschutz und der 25.5.2018, wie ein Damoklesschwert scheinen beide Begriffe zurzeit im Raum zu stehe. Jeder weiß oder sollte zumindest um das Inkrafttreten der europ{\"a}ischen DSGVO am 25.5.2018 wissen. Viel wurde {\"u}ber wesentliche Neuerungen im Datenschutzrecht berichtet. Nicht zuletzt {\"u}ber gesteigerte organisatorische Anforderungen, Dokumentationspflichten und drohende Bußgelder. Doch was bedeuten diese Neuerungen ganz konkret f{\"u}r die Praxis des Steuerberaters? Anders als man vermuten k{\"o}nnte, werden die datenschutzrechtlichen Neuerungen nicht nur im Bereich der Kanzleiorganisation relevant. Auch im Steuerverwaltungsverfahren sieht sich der Steuerberater datenschutzrechtlichen Fragestellungen gegen{\"u}ber, bspw. dann, wenn die Finanzbeh{\"o}rden bei der Verarbeitung der personenbezogenen Daten des Mandanten gegen die DSGVO verstoßen. Gleiches gilt in Bereichen des Besch{\"a}ftigtendatenschutzes. Sowohl der Kanzleiinhaber selbst, als auch seine Arbeitgeber-Mandanten haben die Vorschriften des Besch{\"a}ftigtendatenschutzes einzuhalten. Der Steuerberater ben{\"o}tigt datenschutzrechtliches Know How, welches unmittelbar seine t{\"a}gliche Praxis betrifft. Andernfalls besteht das Risiko, dass dieser mit mehr Fragen, als Antworten zur{\"u}ck bleibt.}, language = {de} } @incollection{Fabo2018, author = {Fabo, Sabine}, title = {Eine dekonstruktive Erinnerungsarbeit}, series = {Doris Frohnapfel, bewaffnete G{\"o}tter = Doris Frohnapfel, armed gods}, booktitle = {Doris Frohnapfel, bewaffnete G{\"o}tter = Doris Frohnapfel, armed gods}, publisher = {RpB Richter-Br{\"u}ckner}, address = {K{\"o}ln}, isbn = {978-3-9817241-2-7}, pages = {31 -- 35}, year = {2018}, language = {de} } @article{BensbergAuthCzarnecki2018, author = {Bensberg, Frank and Auth, Gunnar and Czarnecki, Christian}, title = {Einsatz von Text Analytics zur Unterst{\"u}tzung literaturintensiver Forschungsprozesse: Konzeption, Realisierung und Lessons Learned}, series = {Anwendungen und Konzepte der Wirtschaftsinformatik}, volume = {2018}, journal = {Anwendungen und Konzepte der Wirtschaftsinformatik}, number = {8}, publisher = {AKWI}, address = {Luzern}, issn = {2296-4592}, doi = {10.26034/lu.akwi.2018.3221}, pages = {1 -- 6}, year = {2018}, abstract = {Das anhaltende Wachstum wissenschaftlicher Ver{\"o}ffentlichungen wirft die Fragestellung auf, wie Literaturana-lysen im Rahmen von Forschungsprozessen digitalisiert und somit produktiver realisiert werden k{\"o}nnen. Insbesondere in informationstechnischen Fachgebieten ist die Forschungspraxis durch ein rasant wachsendes Publikationsaufkommen gekennzeichnet. Infolgedessen bietet sich der Einsatz von Methoden der Textanalyse (Text Analytics) an, die Textdaten automatisch vorbereiten und verarbeiten k{\"o}nnen. Erkenntnisse entstehen dabei aus Analysen von Wortarten und Subgruppen, Korrelations- sowie Zeitreihenanalysen. Dieser Beitrag stellt die Konzeption und Realisierung eines Prototypen vor, mit dem Anwender bibliographische Daten aus der etablierten Literaturdatenbank EBSCO Discovery Service mithilfe textanalytischer Methoden erschließen k{\"o}nnen. Der Prototyp basiert auf dem Analysesystem IBM Watson Explorer, das Hochschulen lizenzkostenfrei zur Verf{\"u}gung steht. Potenzielle Adressaten des Prototypen sind Forschungseinrichtungen, Beratungsunternehmen sowie Entscheidungstr{\"a}ger in Politik und Unternehmenspraxis.}, language = {de} } @incollection{Fabo2018, author = {Fabo, Sabine}, title = {Einspr{\"u}che gegen den informierten Himmel ; Wegsehen; Distanzschaffen, Spielen}, series = {Orbitale Irritationen / Herausgeber: REMOTEWORDS: Achim Mohn{\´e} \& Uta Kopp}, booktitle = {Orbitale Irritationen / Herausgeber: REMOTEWORDS: Achim Mohn{\´e} \& Uta Kopp}, publisher = {Herbert von Halem Verlag}, address = {K{\"o}ln}, isbn = {978-3-86962-302-3}, pages = {20 -- 45}, year = {2018}, language = {de} } @article{WeldenSchejaSchoeningetal.2018, author = {Welden, Rene and Scheja, Sabrina and Sch{\"o}ning, Michael Josef and Wagner, Patrick and Wagner, Torsten}, title = {Electrochemical Evaluation of Light-Addressable Electrodes Based on TiO2 for the Integration in Lab-on-Chip Systems}, series = {physica status solidi a : applications and materials sciences}, volume = {215}, journal = {physica status solidi a : applications and materials sciences}, number = {15}, publisher = {Wiley-VCH}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201800150}, pages = {Article number 1800150}, year = {2018}, abstract = {In lab-on-chip systems, electrodes are important for the manipulation (e.g., cell stimulation, electrolysis) within such systems. An alternative to commonly used electrode structures can be a light-addressable electrode. Here, due to the photoelectric effect, the conducting area can be adjusted by modification of the illumination area which enables a flexible control of the electrode. In this work, titanium dioxide based light-addressable electrodes are fabricated by a sol-gel technique and a spin-coating process, to deposit a thin film on a fluorine-doped tin oxide glass. To characterize the fabricated electrodes, the thickness, and morphological structure are measured by a profilometer and a scanning electron microscope. For the electrochemical behavior, the dark current and the photocurrent are determined for various film thicknesses. For the spatial resolution behavior, the dependency of the photocurrent while changing the area of the illuminated area is studied. Furthermore, the addressing of single fluid compartments in a three-chamber system, which is added to the electrode, is demonstrated.}, language = {en} } @inproceedings{JungFrotscherStaat2018, author = {Jung, Alexander and Frotscher, Ralf and Staat, Manfred}, title = {Electromechanical model of hiPSC-derived ventricular cardiomyocytes cocultured with fibroblasts}, series = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, booktitle = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK}, pages = {11 Seiten}, year = {2018}, abstract = {The CellDrum provides an experimental setup to study the mechanical effects of fibroblasts co-cultured with hiPSC-derived ventricular cardiomyocytes. Multi-scale computational models based on the Finite Element Method are developed. Coupled electrical cardiomyocyte-fibroblast models (cell level) are embedded into reaction-diffusion equations (tissue level) which compute the propagation of the action potential in the cardiac tissue. Electromechanical coupling is realised by an excitation-contraction model (cell level) and the active stress arising during contraction is added to the passive stress in the force balance, which determines the tissue displacement (tissue level). Tissue parameters in the model can be identified experimentally to the specific sample.}, language = {en} } @article{MuellerBeckersMussmannetal.2018, author = {M{\"u}ller, Janina and Beckers, Mario and Mußmann, Nina and Bongaerts, Johannes and B{\"u}chs, Jochen}, title = {Elucidation of auxotrophic deficiencies of Bacillus pumilus DSM 18097 to develop a defined minimal medium}, series = {Microbial Cell Factories}, volume = {17}, journal = {Microbial Cell Factories}, number = {1}, publisher = {BioMed Central}, issn = {1475-2859}, doi = {10.1186/s12934-018-0956-1}, pages = {Article No. 106}, year = {2018}, abstract = {Background Culture media containing complex compounds like yeast extract or peptone show numerous disadvantages. The chemical composition of the complex compounds is prone to significant variations from batch to batch and quality control is difficult. Therefore, the use of chemically defined media receives more and more attention in commercial fermentations. This concept results in better reproducibility, it simplifies downstream processing of secreted products and enable rapid scale-up. Culturing bacteria with unknown auxotrophies in chemically defined media is challenging and often not possible without an extensive trial-and-error approach. In this study, a respiration activity monitoring system for shake flasks and its recent version for microtiter plates were used to clarify unknown auxotrophic deficiencies in the model organism Bacillus pumilus DSM 18097. Results Bacillus pumilus DSM 18097 was unable to grow in a mineral medium without the addition of complex compounds. Therefore, a rich chemically defined minimal medium was tested containing basically all vitamins, amino acids and nucleobases, which are essential ingredients of complex components. The strain was successfully cultivated in this medium. By monitoring of the respiration activity, nutrients were supplemented to and omitted from the rich chemically defined medium in a rational way, thus enabling a systematic and fast determination of the auxotrophic deficiencies. Experiments have shown that the investigated strain requires amino acids, especially cysteine or histidine and the vitamin biotin for growth. Conclusions The introduced method allows an efficient and rapid identification of unknown auxotrophic deficiencies and can be used to develop a simple chemically defined tailor-made medium. B. pumilus DSM 18097 was chosen as a model organism to demonstrate the method. However, the method is generally suitable for a wide range of microorganisms. By combining a systematic combinatorial approach based on monitoring the respiration activity with cultivation in microtiter plates, high throughput experiments with high information content can be conducted. This approach facilitates media development, strain characterization and cultivation of fastidious microorganisms in chemically defined minimal media while simultaneously reducing the experimental effort.}, language = {en} } @book{Huening2018, author = {H{\"u}ning, Felix}, title = {Embedded Design For IoT With Renesas Synergy}, publisher = {Renesas Electronics}, address = {D{\"u}sseldorf}, pages = {143 S.}, year = {2018}, language = {en} } @article{ValeroBungCrookston2018, author = {Valero, Daniel and Bung, Daniel Bernhard and Crookston, B.M.}, title = {Energy dissipation of a Type III basin under design and adverse conditions for stepped and smooth spillways}, series = {Journal of Hydraulic Engineering}, volume = {144}, journal = {Journal of Hydraulic Engineering}, number = {7}, publisher = {ASCE}, address = {Reston, Va.}, issn = {0733-9429}, doi = {10.1061/(ASCE)HY.1943-7900.0001482}, year = {2018}, abstract = {New information regarding the influence of a stepped chute on the hydraulic performance of the United States Bureau of Reclamation (Reclamation) Type III hydraulic jump stilling basin is presented for design (steady) and adverse (decreasing tailwater) conditions. Using published experimental data and computational fluid dynamics (CFD) models, this paper presents a detailed comparison between smooth-chute and stepped-chute configurations for chute slopes of 0.8H:1V and 4H:1V and Froude numbers (F) ranging from 3.1 to 9.5 for a Type III basin designed for F = 8. For both stepped and smooth chutes, the relative role of each basin element was quantified, up to the most hydraulic extreme case of jump sweep-out. It was found that, relative to a smooth chute, the turbulence generated by a stepped chute causes a higher maximum velocity decay within the stilling basin, which represents an enhancement of the Type III basin's performance but also a change in the relative role of the basin elements. Results provide insight into the ability of the CFD models [unsteady Reynolds-averaged Navier-Stokes (RANS) equations with renormalization group (RNG) k-ϵ turbulence model and volume-of-fluid (VOF) for free surface tracking] to predict the transient basin flow structure and velocity profiles. Type III basins can perform adequately with a stepped chute despite the effects steps have on the relative role of each basin element. It is concluded that the classic Type III basin design, based upon methodology by reclamation specific to smooth chutes, can be hydraulically improved for the case of stepped chutes for design and adverse flow conditions using the information presented herein.}, language = {en} } @incollection{LeiseAltherrPelz2018, author = {Leise, Philipp and Altherr, Lena and Pelz, Peter F.}, title = {Energy-Efficient design of a water supply system for skyscrapers by mixed-integer nonlinear programming}, series = {Operations Research Proceedings 2017}, booktitle = {Operations Research Proceedings 2017}, publisher = {Springer}, address = {Cham}, isbn = {978-3-319-89919-0}, doi = {10.1007/978-3-319-89920-6_63}, year = {2018}, abstract = {The energy-efficiency of technical systems can be improved by a systematic design approach. Technical Operations Research (TOR) employs methods known from Operations Research to find a global optimal layout and operation strategy of technical systems. We show the practical usage of this approach by the systematic design of a decentralized water supply system for skyscrapers. All possible network options and operation strategies are modeled by a Mixed-Integer Nonlinear Program. We present the optimal system found by our approach and highlight the energy savings compared to a conventional system design.}, language = {en} } @article{TekinAshikagaHorikawaetal.2018, author = {Tekin, Nurettin and Ashikaga, Mitsugu and Horikawa, Atsushi and Funke, Harald}, title = {Enhancement of fuel flexibility of industrial gas turbines by development of innovative hydrogen combustion systems}, series = {Gas for energy}, journal = {Gas for energy}, number = {2}, publisher = {Vulkan-Verlag}, address = {Essen}, pages = {4}, year = {2018}, abstract = {For fuel flexibility enhancement hydrogen represents a possible alternative gas turbine fuel within future low emission power generation, in case of hydrogen production by the use of renewable energy sources such as wind energy or biomass. Kawasaki Heavy Industries, Ltd. (KHI) has research and development projects for future hydrogen society; production of hydrogen gas, refinement and liquefaction for transportation and storage, and utilization with gas turbine / gas engine for the generation of electricity. In the development of hydrogen gas turbines, a key technology is the stable and low NOx hydrogen combustion, especially Dry Low Emission (DLE) or Dry Low NOx (DLN) hydrogen combustion. Due to the large difference in the physical properties of hydrogen compared to other fuels such as natural gas, well established gas turbine combustion systems cannot be directly applied for DLE hydrogen combustion. Thus, the development of DLE hydrogen combustion technologies is an essential and challenging task for the future of hydrogen fueled gas turbines. The DLE Micro-Mix combustion principle for hydrogen fuel has been in development for many years to significantly reduce NOx emissions. This combustion principle is based on cross-flow mixing of air and gaseous hydrogen which reacts in multiple miniaturized "diffusion-type" flames. The major advantages of this combustion principle are the inherent safety against flashback and the low NOx-emissions due to a very short residence time of the reactants in the flame region of the micro-flames.}, language = {en} } @inproceedings{HofmannMatareNeumannetal.2018, author = {Hofmann, Till and Matar{\´e}, Victor and Neumann, Tobias and Sch{\"o}nitz, Sebastian and Henke, Christoph and Limpert, Nicolas and Niemueller, Tim and Ferrein, Alexander and Jeschke, Sabina and Lakemeyer, Gerhard}, title = {Enhancing Software and Hardware Reliability for a Successful Participation in the RoboCup Logistics League 2017}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-00308-1}, doi = {10.1007/978-3-030-00308-1_40}, pages = {486 -- 497}, year = {2018}, language = {en} }