@inproceedings{HartmannKallweitFeldusenetal.2012,
  author    = {Hartmann, Axel and Kallweit, Stephan and Feldusen, Antje and Schr{\"o}der, Wolfgang},
  title     = {Detection of upstream propagating sound waves at buffet flow using high-speed PIV},
  pages     = {14 S. : graph. Darst.},
  year      = {2012},
  language  = {en}
}
@inproceedings{BohrnMuchaWerneretal.2012,
  author    = {Bohrn, Ulrich and Mucha, Andreas and Werner, Frederik and St{\"u}tz, Evamaria and B{\"a}cker, Matthias and Krumbe, Christoph and Schienle, Meinrad and Fleischer, Maximilian and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Detection of toxic chromium species in water using cellbased sensor systems},
  isbn      = {978-3-9813484-2-2},
  doi       = {10.5162/IMCS2012/P2.1.14},
  pages     = {1364 -- 1367},
  year      = {2012},
  language  = {en}
}
@article{KernSchelthoffMathieu2012,
  author    = {Kern, Alexander and Schelthoff, Christof and Mathieu, Moritz},
  title     = {Detaillierte Berechnung der Einfangwirksamkeiten von Fangeinrichtungen},
  series = {Elektro-Praktiker},
  volume    = {66},
  journal   = {Elektro-Praktiker},
  number    = {4},
  publisher = {Huss Medien},
  address   = {Berlin},
  issn      = {0013-5569},
  pages     = {6 Seiten},
  year      = {2012},
  abstract  = {Im Beitrag wird zun{\"a}chst das Verfahren eines dynamischen elektro-geometrischen Modells vorgestellt. Dieses arbeitet im Gegensatz zum klassischen Blitzkugel-Verfahren nicht mit konstanten Radien; vielmehr wird der Radius der Blitzkugel variiert. Dabei werden ausschließlich vorhandene und in internationalen Normen anerkannte Ergebnisse, blitzphysikalische Grundlagen und Untersuchungen verwendet, und auf deren Grundlage ein numerisches Verfahren erarbeitet. Mit dem dynamischen elektro-geometrischen Modell werden dann einige Beispiele des Schutzes mit Fangstangen, die gem{\"a}ß dem klassischen Blitzkugel-Verfahren nach DIN EN 62305-3 f{\"u}r die Schutzklassen I - II - III - IV geplant sind, untersucht. Es wird gezeigt, dass die Einfangwirksamkeiten wesentlich h{\"o}her sind als in der Normenreihe DIN EN 62305 selbst angegeben. Grund daf{\"u}r ist die Tatsache, dass das Blitzkugel-Verfahren sehr konservativ aufgebaut ist und dem Planer von Blitzschutzsystemen nur die m{\"o}glichen Stellen f{\"u}r einen Einschlag aufzeigt, ohne eine Bewertung der Einschlagsh{\"a}ufigkeit zu liefern. Andererseits bedeutet dies jedoch, dass man mit dem klassischen Blitzkugel-Verfahren stets auf der „sicheren Seite" liegt.},
  language  = {de}
}
@article{FrauenrathFuchsDieringeretal.2012,
  author    = {Frauenrath, Tobias and Fuchs, Katharina and Dieringer, Matthias A. and {\"O}zerdem, Celal and Patel, Nishan and Renz, Wolfgang and Greiser, Andreas and Elgeti, Thomas and Niendorf, Thoralf},
  title     = {Detailing the use of magnetohydrodynamic effects for synchronization of MRI with the cardiac cycle: A feasibility study},
  series = {Journal of Magnetic Resonance Imaging},
  volume    = {36},
  journal   = {Journal of Magnetic Resonance Imaging},
  number    = {2},
  publisher = {Wiley-Liss},
  address   = {New York},
  issn      = {1522-2586},
  doi       = {10.1002/jmri.23634},
  pages     = {364 -- 372},
  year      = {2012},
  abstract  = {Purpose: To investigate the feasibility of using magnetohydrodynamic (MHD) effects for synchronization of magnetic resonance imaging (MRI) with the cardiac cycle. Materials and Methods: The MHD effect was scrutinized using a pulsatile flow phantom at B0 = 7.0 T. MHD effects were examined in vivo in healthy volunteers (n = 10) for B0 ranging from 0.05-7.0 T. Noncontrast-enhanced MR angiography (MRA) of the carotids was performed using a gated steady-state free-precession (SSFP) imaging technique in conjunction with electrocardiogram (ECG) and MHD synchronization. Results: The MHD potential correlates with flow velocities derived from phase contrast MRI. MHD voltages depend on the orientation between B0 and the flow of a conductive fluid. An increase in the interelectrode spacing along the flow increases the MHD potential. In vivo measurement of the MHD effect provides peak voltages of 1.5 mV for surface areas close to the common carotid artery at B0 = 7.0 T. Synchronization of MRI with the cardiac cycle using MHD triggering is feasible. MHD triggered MRA of the carotids at 3.0 T showed an overall image quality and richness of anatomic detail, which is comparable to ECG-triggered MRAs. Conclusion: This feasibility study demonstrates the use of MHD effects for synchronization of MR acquisitions with the cardiac cycle. J. Magn. Reson. Imaging 2012;36:364-372. © 2012 Wiley Periodicals, Inc.},
  language  = {en}
}
@article{LeursMezoOehlschlaegeretal.2012,
  author    = {Leurs, Ulrike and Mezo, Gabor and {\"O}hlschl{\"a}ger, Peter and Orban, Erika and Marquard, Andrea and Manea, Marilena},
  title     = {Design, synthesis, in vitro stability and cytostatic effect of multifunctional anticancer drug-bioconjugates containing GnRH-III as a targeting moiety},
  series = {Peptide Science},
  volume    = {98},
  journal   = {Peptide Science},
  number    = {1},
  publisher = {Wiley},
  address   = {New York, NY},
  issn      = {1097-0282},
  doi       = {10.1002/bip.21640},
  pages     = {1 -- 10},
  year      = {2012},
  abstract  = {Bioconjugates containing the GnRH-III hormone decapeptide as a targeting moiety are able to deliver chemotherapeutic agents specifically to cancer cells expressing GnRH receptors, thereby increasing their local efficacy while limiting the peripheral toxicity. However, the number of GnRH receptors on cancer cells is limited and they desensitize under continuous hormone treatment. A possible approach to increase the receptor mediated tumor targeting and consequently the cytostatic effect of the bioconjugates would be the attachment of more than one chemotherapeutic agent to one GnRH-III molecule. Here we report on the design, synthesis and biochemical characterization of multifunctional bioconjugates containing GnRH-III as a targeting moiety and daunorubicin as a chemotherapeutic agent. Two different drug design approaches were pursued. The first one was based on the bifunctional [4Lys]-GnRH-III (Glp-His-Trp-Lys-His-Asp-Trp-Lys-Pro-Gly-NH2) containing two lysine residues in positions 4 and 8, whose ϵ-amino groups were used for the coupling of daunorubicin. In the second drug design, the native GnRH-III (Glp-His-Trp-Ser-His-Asp-Trp-Lys-Pro-Gly-NH2) was used as a scaffold; an additional lysine residue was coupled to the ϵ-amino group of 8Lys in order to generate two free amino groups available for conjugation of daunorubicin. The in vitro stability/degradation of all synthesized compounds was investigated in human serum, as well as in the presence of rat liver lysosomal homogenate. Their cellular uptake was determined on human breast cancer cells and the cytostatic effect was evaluated on human breast, colon and prostate cancer cell lines. Compared with a monofunctional compound, both drug design approaches resulted in multifunctional bioconjugates with increased cytostatic effect.},
  language  = {en}
}
@misc{GraesslRenzHezeletal.2012,
  author    = {Gr{\"a}ßl, Andreas and Renz, Wolfgang and Hezel, Fabian and Frauenrath, Tobias and Pfeiffer, Harald and Hoffmann, Werner and Kellmann, Peter and Martin, Conrad and Niendorf, Thoralf},
  title     = {Design, evaluation and application of a modular 32 channel transmit/receive surface coil array for cardiac MRI at 7T},
  series = {2012 ISMRM Annual Meeting Proceedings},
  journal   = {2012 ISMRM Annual Meeting Proceedings},
  issn      = {1545-4428},
  year      = {2012},
  abstract  = {Cardiac MR (CMR) at ultrahigh (≥7.0 T) fields is regarded as one of the most challenging MRI applications. At 7.0 T image quality is not always exclusively defined by signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR). Detrimental effects bear the potential to spoil the signal-to-noise (SNR) and contrast-to-noise (CNR) benefits of cardiac MR (CMR) at 7.0 T. B₁⁺-inhomogeneities and signal voids represent the main challenges. Various pioneering coil concepts have been proposed to tackle these issues, enabling cardiac MRI at 7.0 T. This includes a trend towards an ever larger number of transmit and receive channels. This approach affords multi-dimensional B₁⁺ modulations to improve B₁⁺ shimming performance and to enhance RF efficiency. Also, parallel imaging benefits from a high number of receive channels enabling two-dimensional acceleration. Realizing the limitations of existing coil designs tailored for UHF CMR and recognizing the opportunities of a many element TX/RX channel architecture this work proposes a modular, two dimensional 32-channel transmit and receive array using loop elements and examines its efficacy for enhanced B¹+ homogeneity and improved parallel imaging performance.},
  language  = {en}
}
@article{ChludekTran2012,
  author    = {Chludek, Astrid and Tran, Duc Hung},
  title     = {Der Reformvorschlag des IAS 12 gem. ED/2009/2 - Ein Pl{\"a}doyer f{\"u}r die Einf{\"u}hrung der valuation allowance},
  series = {KoR Zeitschrift f{\"u}r kapitalmarktorientierte Rechnungslegung},
  journal   = {KoR Zeitschrift f{\"u}r kapitalmarktorientierte Rechnungslegung},
  number    = {1},
  publisher = {Fachmedien Otto Schmidt},
  address   = {D{\"u}sseldorf},
  issn      = {1617-8084},
  pages     = {4 -- 8},
  year      = {2012},
  language  = {de}
}
@techreport{ButenwegDargelHoechstetal.2012,
  author    = {Butenweg, Christoph and Dargel, H.-J. and H{\"o}chst, T. and Holtschoppen, B. and Schwarz, R. and Sippel, M.},
  title     = {Der Lastfall Erdbeben im Anlagenbau : Leitfaden : Entwurf, Bemessung und Konstruktion von Tragwerken und Komponenten in der chemischen Industrie in Anlehnung an die DIN EN 1998-1},
  publisher = {Verband der Chemischen Industrie e.V.},
  address   = {Frankfurt},
  pages     = {20 S.},
  year      = {2012},
  language  = {de}
}
@inproceedings{BeckerEggertFleischeretal.2012,
  author    = {Becker, J{\"o}rg and Eggert, Mathias and Fleischer, Stefan and Heddier, Marcel and Knackstedt, Ralf},
  title     = {Data Warehouse Design and Legal Visualization - The Applicability of H2 for Reporting},
  series = {Proceedings of the 23rd Australasian Conference on Information Systems 2012},
  booktitle = {Proceedings of the 23rd Australasian Conference on Information Systems 2012},
  pages     = {11 S.},
  year      = {2012},
  language  = {de}
}
@inproceedings{FissabreSchmidtSonnleitner2012,
  author    = {Fissabre, Anke and Schmidt, Klaus and Sonnleitner, Andrea},
  title     = {Das Lehnsm{\"u}hlschloß in Ortrand - ein s{\"a}chsisches Herrenhaus der Renaissance},
  series = {Wandel im Wohnbau zwischen Gotik und Barock : die s{\"a}chsisch-b{\"o}hmische Entwicklung im {\"u}berregionalen Vergleich},
  booktitle = {Wandel im Wohnbau zwischen Gotik und Barock : die s{\"a}chsisch-b{\"o}hmische Entwicklung im {\"u}berregionalen Vergleich},
  publisher = {Jonas},
  address   = {Marburg},
  isbn      = {978-3-89445-390-9},
  pages     = {487 -- 501},
  year      = {2012},
  language  = {de}
}
@inproceedings{KoetterDeckerDetzleretal.2012,
  author    = {K{\"o}tter, Jens and Decker, Stefan and Detzler, Raphael and Sch{\"a}fer, Jochen and Schmitz, Mark and Herrmann, Ulf},
  title     = {Cost Reduction of Solar Fields with HelioTrough Collector},
  publisher = {FLAGSOL},
  address   = {K{\"o}ln},
  pages     = {9 S. : Ill., graph. Darst.},
  year      = {2012},
  language  = {en}
}
@incollection{HoffschmidtAlexopoulosRauetal.2012,
  author    = {Hoffschmidt, Bernhard and Alexopoulos, Spiros and Rau, Christoph and Sattler, Johannes, Christoph and Anthrakidis, Anette and Teixeira Boura, Cristiano Jos{\´e} and O'Connor, P. and Hilger, Patrick},
  title     = {Concentrating solar power},
  series = {Comprehensive renewable energy / ed. Ali Sayigh. Vol. 3: Solar thermal systems: components and applications},
  volume    = {3},
  booktitle = {Comprehensive renewable energy / ed. Ali Sayigh. Vol. 3: Solar thermal systems: components and applications},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {978-0-08-087872-0},
  doi       = {10.1016/B978-0-08-087872-0.00319-X},
  pages     = {595 -- 636},
  year      = {2012},
  language  = {en}
}
@inproceedings{TakenagaWernerSawadaetal.2012,
  author    = {Takenaga, Shoko and Werner, Frederik and Sawada, Kazuaki and Sch{\"o}ning, Michael Josef},
  title     = {Comparison of label-free ACh image sensors based on CCD and LAPS},
  isbn      = {978-3-9813484-2-2},
  doi       = {10.5162/IMCS2012/4.2.6},
  pages     = {356 -- 359},
  year      = {2012},
  language  = {en}
}
@article{HuckPoghossianWagneretal.2012,
  author    = {Huck, Christina and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Combined amperometric/field-effect sensor for the detection of dissolved hydrogen},
  series = {Sensors and actuators B: Chemical},
  volume    = {187},
  journal   = {Sensors and actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2012.10.050},
  pages     = {168 -- 173},
  year      = {2012},
  abstract  = {Real-time and reliable monitoring of the biogas process is crucial for a stable and efficient operation of biogas production in order to avoid digester breakdowns. The concentration of dissolved hydrogen (H₂) represents one of the key parameters for biogas process control. In this work, a one-chip integrated combined amperometric/field-effect sensor for monitoring the dissolved H₂ concentration has been developed for biogas applications. The combination of two different transducer principles might allow a more accurate and reliable measurement of dissolved H₂ as an early warning indicator of digester failures. The feasibility of the approach has been demonstrated by simultaneous amperometric/field-effect measurements of dissolved H₂ concentrations in electrolyte solutions. Both, the amperometric and the field-effect transducer show a linear response behaviour in the H₂ concentration range from 0.1 to 3\% (v/v) with a slope of 198.4 ± 13.7 nA/\% (v/v) and 14.9 ± 0.5 mV/\% (v/v), respectively.},
  language  = {en}
}
@article{SchoeningBaecker2012,
  author    = {Sch{\"o}ning, Michael Josef and B{\"a}cker, Matthias},
  title     = {Chip-basierte Sensoren f{\"u}r die Biotechnik},
  volume    = {13},
  number    = {2},
  publisher = {BIOCOM},
  address   = {Berlin},
  issn      = {1611-0854},
  year      = {2012},
  language  = {de}
}
@article{MiyamotoIchimuraWagneretal.2012,
  author    = {Miyamoto, K. and Ichimura, H. and Wagner, Torsten and Yoshinobu, T. and Sch{\"o}ning, Michael Josef},
  title     = {Chemical Imaging of ion Diffusion in a Microfluidic Channel},
  series = {Procedia Engineering},
  journal   = {Procedia Engineering},
  number    = {47},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2012.09.289},
  pages     = {886 -- 889},
  year      = {2012},
  abstract  = {The chemical imaging sensor is a chemical sensor which is capable of visualizing the spatial distribution of chemical species in sample solution. In this study, a novel measurement system based on the chemical imaging sensor was developed to observe the inside of a Y-shaped microfluidic channel while injecting two sample solutions from two branches. From the collected chemical images, it was clearly observed that the injected solutions formed laminar flows in the microfluidic channel. In addition, ion diffusion across the laminar flows was observed. This label-free method can acquire quantitative data of ion distribution and diffusion in microfluidic devices, which can be used to determine the diffusion coefficients, and therefore, the molecular weights of chemical species in the sample solution.},
  language  = {en}
}
@article{SchusserPoghossianBaeckeretal.2012,
  author    = {Schusser, Sebastian and Poghossian, Arshak and B{\"a}cker, Matthias and Leinhos, Marcel and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Characterization of biodegradable polymers with capacitive field-effect sensors},
  series = {Sensors and actuators B: Chemical},
  volume    = {187},
  journal   = {Sensors and actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2012.07.099},
  pages     = {2 -- 7},
  year      = {2012},
  abstract  = {In vitro studies of the degradation kinetic of biopolymers are essential for the design and optimization of implantable biomedical devices. In the presented work, a field-effect capacitive sensor has been applied for the real-time and in situ monitoring of degradation processes of biopolymers for the first time. The polymer-covered field-effect sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. The feasibility of this approach has been experimentally proven by using the commercially available biomedical polymer poly(D,L-lactic acid) (PDLLA) as a model system. PDLLA films of different thicknesses were deposited on the Ta₂O₅-gate surface of the field-effect structure from a polymer solution by means of spin-coating method. The polymer-modified field-effect sensors have been characterized by means of capacitance-voltage and impedance-spectroscopy method. The degradation of the PDLLA was accelerated by changing the degradation medium from neutral (pH 7.2) to alkaline (pH 9) condition, resulting in drastic changes in the capacitance and impedance spectra of the polymer-modified field-effect sensor.},
  language  = {en}
}
@inproceedings{OertelBung2012,
  author    = {Oertel, Mario and Bung, Daniel Bernhard},
  title     = {Characteristics of cross-bar block ramp flows},
  series = {Hydraulic structures into the 21st century : 4th IAHR International Symposium on Hydraulic Structures : 9.-11.2.2012, Porto},
  booktitle = {Hydraulic structures into the 21st century : 4th IAHR International Symposium on Hydraulic Structures : 9.-11.2.2012, Porto},
  organization    = {International Symposium on Hydraulic Structures <4, 2012, Porto>},
  isbn      = {978-989-8509-01-7},
  pages     = {Elektronisch publiziert},
  year      = {2012},
  language  = {en}
}
@article{KirchnerReisertPuetzetal.2012,
  author    = {Kirchner, Patrick and Reisert, Steffen and P{\"u}tz, Patrick and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Characterisation of polymeric materials as passivation layer for calorimetric H2O2 gas sensors},
  series = {Physica Status Solidi (a)},
  volume    = {209},
  journal   = {Physica Status Solidi (a)},
  number    = {5},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201100773},
  pages     = {859 -- 863},
  year      = {2012},
  abstract  = {Calorimetric gas sensors for monitoring the H₂O₂ concentration at elevated temperatures in industrial sterilisation processes have been presented in previous works. These sensors are built up in form of a differential set-up of a catalytically active and passive temperature-sensitive structure. Although, various types of catalytically active dispersions have been studied, the passivation layer has to be established and therefore, chemically as well as physically characterised. In the present work, fluorinated ethylene propylene (FEP), perfluoralkoxy (PFA) and epoxy-based SU-8 photoresist as temperature-stable polymeric materials have been investigated for sensor passivation in terms of their chemical inertness against H₂O₂, their hygroscopic properties as well as their morphology. The polymeric materials were deposited via spin-coating on the temperature-sensitive structure, wherein spin-coated FEP and PFA show slight agglomerates. However, they possess a low absorption of humidity due to their hydrophobic surface, whereas the SU-8 layer has a closed surface but shows a slightly higher absorption of water. All of them were inert against gaseous H₂O₂ during the characterisation in H₂O₂ atmosphere that demonstrates their suitability as passivation layer for calorimetric H₂O₂ gas sensors.},
  language  = {en}
}
@inproceedings{ReisertGeisslerFloerkeetal.2012,
  author    = {Reisert, Steffen and Geissler, H. and Fl{\"o}rke, R. and Weiler, C. and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Characterisation of aseptic sterilisation processes using an electronic nose},
  series = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  booktitle = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  editor    = {Abdelghani, Adnane and Sch{\"o}ning, Michael Josef},
  pages     = {45 -- 45},
  year      = {2012},
  language  = {en}
}
@misc{TkachenkovonKnobelsdorffBrenkenhoffKleindienstetal.2012,
  author    = {Tkachenko, Valeriy and von Knobelsdorff-Brenkenhoff, Florian and Kleindienst, Denise and Winter, Lukas and Rieger, Jan and Frauenrath, Tobias and Dieringer, Matthias A. and Santoro, Davide and Niendorf, Thoralf and Schulz-Menger, Jeanette},
  title     = {Cardiovasular MR at 7Tesla: assessment of the right ventricle},
  series = {2012 ISMRM Annual Meeting Proceedings},
  journal   = {2012 ISMRM Annual Meeting Proceedings},
  issn      = {1545-4428},
  year      = {2012},
  abstract  = {The assessment of the right ventricle (RV) is a challenge in today's cardiology, but of growing clinical impact regarding patient prognosis in different cardiac diseases. The detection and differentiation of small wall motion abnormalities may help to enhance the differentiation of cardiomyopathies including Arrhythmogenic Rightventricular Cardiomyopathy. Cardiovascular magnetic resonance (CMR) at 1.5T is the accepted gold standard for RV quantification. The higher spatial resolution achievable at ultrahigh field strength (UHF) offers the potential to gain new insights into the structure and function of the RV. To approach this goal accurate RV chamber quantification at 7T has to be proven. Consequently this study examines the feasibility of assessment of RV dimensions and function at 7T using improved spatial resolution enabled by the intrinsic sensitivity gain of UHF CMR. For this purpose, a dedicated 16 channel TX/RX RF coil array is used together with 2D CINE fast gradient echo (FGRE) imaging. For comparison RV chamber quantification is conducted at 1.5T using a SSFP based state of the art clinical protocol.},
  language  = {en}
}
@misc{LindelGreiserWaxmanetal.2012,
  author    = {Lindel, Tomasz Dawid and Greiser, Andreas and Waxman, Patrick and Dietterle, Martin and Seifert, Frank and Fontius, Ulrich and Renz, Wolfgang and Dieringer, Matthias A. and Frauenrath, Tobias and Schulz-Menger, Jeanette and Niendorf, Thoralf and Ittermann, Bernd},
  title     = {Cardiac CINE MRI at 7 T using a transmit array},
  series = {2012 ISMRM Annual Meeting Proceedings},
  journal   = {2012 ISMRM Annual Meeting Proceedings},
  issn      = {1545-4428},
  year      = {2012},
  abstract  = {With its need for high SNR and short acquisition times, Cardiac MRI (CMR) is an intriguing target application for ultrahigh field MRI. Due to the sheer size of the upper torso, however, the known RF issues of 7T MRI are also most prominent in CMR. Recent years brought substantial progress but the full potential of the ultrahigh field for CMR is yet to be exploited. Parallel transmission (pTx) is a promising approach in this context and several groups have already reported B1 shimming for 7T CMR. In such a static pTx application amplitudes and phases of all Tx channels are adjusted individually but otherwise imaging techniques established in current clinical practice 1.5 T and 3 T are applied. More advanced forms of pTx as spatially selective excitation (SSE) using Transmit SENSE promise additional benefits like faster imaging with reduced fields of view or improved SAR control. SSE requires the full dynamic capabilities of pTx, however, and for the majority of today's implemented pTx hardware the internal synchronization of the Tx array does not easily permit external triggering as needed for CMR. Here we report a software solution to this problem and demonstrate the feasibility of CINE CMR at 7 T using a Tx array.},
  language  = {en}
}
@inproceedings{KernSchelthoffMathieu2012,
  author    = {Kern, Alexander and Schelthoff, Christof and Mathieu, Moritz},
  title     = {Calculation of interception efficiencies for mesh-type air-terminations according to IEC 62305-3 using a dynamic electro-geometrical model},
  series = {International Conference on Lightning Protection (ICLP) : 2 - 7 Sept. 2012, Vienna},
  booktitle = {International Conference on Lightning Protection (ICLP) : 2 - 7 Sept. 2012, Vienna},
  publisher = {IEEE},
  address   = {Piscataway, NJ},
  organization    = {International Conference on Lightning Protection <2012, Wien>},
  isbn      = {978-1-4673-1896-9 (E-Book) ; 978-1-4673-1898-3 (Print)},
  pages     = {1 -- 6},
  year      = {2012},
  language  = {en}
}
@article{SchifferFerreinLakemeyer2012,
  author    = {Schiffer, Stefan and Ferrein, Alexander and Lakemeyer, Gerhard},
  title     = {Caesar: an intelligent domestic service robot},
  series = {Intelligent service robotics},
  volume    = {5},
  journal   = {Intelligent service robotics},
  number    = {4},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1861-2776},
  doi       = {10.1007/s11370-012-0118-y},
  pages     = {259 -- 276},
  year      = {2012},
  abstract  = {In this paper we present CAESAR, an intelligent domestic service robot. In domestic settings for service robots complex tasks have to be accomplished. Those tasks benefit from deliberation, from robust action execution and from flexible methods for human-robot interaction that account for qualitative notions used in natural language as well as human fallibility. Our robot CAESAR deploys AI techniques on several levels of its system architecture. On the low-level side, system modules for localization or navigation make, for instance, use of path-planning methods, heuristic search, and Bayesian filters. For face recognition and human-machine interaction, random trees and well-known methods from natural language processing are deployed. For deliberation, we use the robot programming and plan language READYLOG, which was developed for the high-level control of agents and robots; it allows combining programming the behaviour using planning to find a course of action. READYLOG is a variant of the robot programming language Golog. We extended READYLOG to be able to cope with qualitative notions of space frequently used by humans, such as "near" and "far". This facilitates human-robot interaction by bridging the gap between human natural language and the numerical values needed by the robot. Further, we use READYLOG to increase the flexible interpretation of human commands with decision-theoretic planning. We give an overview of the different methods deployed in CAESAR and show the applicability of a system equipped with these AI techniques in domestic service robotics},
  language  = {en}
}
@article{SchmitzWeber2012,
  author    = {Schmitz, Philipp and Weber, Martin},
  title     = {Buying and selling behavior of individual investors in option-like securities},
  series = {Die Betriebswirtschaft : DBW},
  volume    = {72},
  journal   = {Die Betriebswirtschaft : DBW},
  number    = {5},
  publisher = {Sch{\"a}ffer-Poeschel},
  address   = {Stuttgart},
  issn      = {0342-7064},
  doi       = {10.2139/ssrn.2055088},
  pages     = {409 -- 426},
  year      = {2012},
  abstract  = {We analyze the trading behavior of individual investors in option-like securities, namely bankissued warrants, and thus expand the growing literature of investors behavior to a new kind of securities. A unique data set from a large German discount broker gives us the opportunity to analyze the trading behavior of 1,454 investors, making 89,958 transactions in 6,724 warrants on 397 underlyings. In different logit regression, we make use of the facts that investors can speculate on rising and falling prices of the underlying with call and put warrants and that we also have information about the stock portfolios of the investors. We report several facts about the trading behavior of individual investors in warrants that are consistent with the literature on the behavior of individual investors in the stock market. The warrant investors buy calls and sell puts if the price of the underlying has decreased over the past trading days and they sell calls and buy puts if the price of the underlying has increased. That means, the investors follow negative feedback trading strategies in all four trading categories observed. In addition, we find strong evidence for the disposition effect for call as well as put warrants, which is reversed in December. The trading behavior is also influenced if the underlying reaches some exceptionally prices, e.g. highs, lows or the strike price. We show that hedging, as one natural candidate to buy puts, does not play an important role in the market for bank-issued warrants.},
  language  = {en}
}
@inproceedings{OertelBungSchlenkhoff2012,
  author    = {Oertel, Mario and Bung, Daniel Bernhard and Schlenkhoff, Andreas},
  title     = {Blocksteinrampen in Riegelbauweise : Neue Bemessungsans{\"a}tze},
  series = {Staubauwerke : planen, bauen, betreiben; 35. Dresdner Wasserbaukolloquium 2012, 08. - 09. M{\"a}rz 2012},
  booktitle = {Staubauwerke : planen, bauen, betreiben; 35. Dresdner Wasserbaukolloquium 2012, 08. - 09. M{\"a}rz 2012},
  editor    = {Carstensen, Dirk},
  publisher = {Selbstverl. der Techn. Univ.},
  address   = {Dresden},
  organization    = {Technische Universit{\"a}t Dresden, Fakult{\"a}t Bauingenieurwesen},
  isbn      = {978-3-86780-261-1},
  pages     = {317 -- 326},
  year      = {2012},
  language  = {de}
}
@inproceedings{SchusserLeinhosPoghossianetal.2012,
  author    = {Schusser, Sebastian and Leinhos, Marcel and Poghossian, Arshak and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Biopolymer-degradation monitoring by chip-­based impedance spectroscopy technique},
  series = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  booktitle = {Nanoscale Science and Technology (NS\&T´12) : Proceedings Book Humboldt Kolleg ; Tunisia, 17-19 March, 2012},
  editor    = {Abdelghani, Adnane and Sch{\"o}ning, Michael Josef},
  pages     = {47 -- 47},
  year      = {2012},
  language  = {en}
}
@article{Alexopoulos2012,
  author    = {Alexopoulos, Spiros},
  title     = {Biogas systems: basics, biogas multifunction, principle of fermentation and hybrid application with a solar tower for the treatment of waste animal manure},
  series = {Journal of Engineering Science and Technology Review},
  volume    = {5},
  journal   = {Journal of Engineering Science and Technology Review},
  number    = {4},
  issn      = {1791-2377},
  pages     = {48 -- 55},
  year      = {2012},
  abstract  = {Two of the main environmental problems of today's society are the continuously increasing production of organic wastes as well as the increase of carbon dioxide in the atmosphere and the related green house effect. A way to solve these problems is the production of biogas. Biogas is a combustible gas consisting of methane, carbon dioxide and small amounts of other gases and trace elements. Production of biogas through anaerobic digestion of animal manure and slurries as well as of a wide range of digestible organic wastes and agricultural residues, converts these substrates into electricity and heat and offers a natural fertiliser for agriculture. The microbiological process of decomposition of organic matter, in the absence of oxygen takes place in reactors, called digesters. Biogas can be used as a fuel in a gas turbine or burner and can be used in a hybrid solar tower system offering a solution for waste treatment of agricultural and animal residues. A solar tower system consists of a heliostat field, which concentrates direct solar irradiation on an open volumetric central receiver. The receiver heats up ambient air to temperatures of around 700°C. The hot air's heat energy is transferred to a steam Rankine cycle in a heat recovery steam generator (HRSG). The steam drives a steam turbine, which in turn drives a generator for producing electricity. In order to increase the operational hours of a solar tower power plant, a heat storage system and/ or hybridization may be considered. The advantage of solar-fossil hybrid power plants, compared to solar-only systems, lies in low additional investment costs due to an adaptable solar share and reduced technical and economical risks. On sunny days the hybrid system operates in a solar-only mode with the central receiver and on cloudy days and at night with the gas turbine only. As an alternative to methane gas, environmentally neutral biogas can be used for operating the gas turbine. Hence, the hybrid system is operated to 100\% from renewable energy sources},
  language  = {en}
}
@article{MansurovDigelBiisenbaevetal.2012,
  author    = {Mansurov, Z. and Digel, Ilya and Biisenbaev, M. and Savistkaya, I. and Kistaubaeva, A. and Akimbekov, Nuraly S. and Zhubanova, A.},
  title     = {Bio-composite material on the basis of carbonized rice husk in biomedicine and environmental applications},
  series = {Eurasian Chemico-Technological Journal},
  volume    = {14},
  journal   = {Eurasian Chemico-Technological Journal},
  number    = {2},
  publisher = {Institute of Combustion Problems},
  address   = {Almaty},
  issn      = {2522-4867},
  doi       = {10.18321/ectj105},
  pages     = {115 -- 131},
  year      = {2012},
  language  = {en}
}
@book{Timme2012,
  author    = {Timme, Michael},
  title     = {BGB Crashkurs : der sichere Weg durch die Pr{\"u}fung ; [Fall f{\"u}r Fall durch das Privatrecht]. - 2. Aufl.},
  publisher = {Beck},
  address   = {M{\"u}nchen},
  isbn      = {978-3-406-63681-3},
  pages     = {160 S.},
  year      = {2012},
  language  = {de}
}
@article{TimmeGuennewig2012,
  author    = {Timme, Michael and G{\"u}nnewig, Sebastian},
  title     = {Betriebskostenabrechnung - Die Pflicht des Vermieters zur Beachtung des Wirtschaftlichkeitsgebots},
  series = {Der Miet-Rechts-Berater : MietRB ; Miete, Immobilien, Wohnungseigentum},
  journal   = {Der Miet-Rechts-Berater : MietRB ; Miete, Immobilien, Wohnungseigentum},
  number    = {3},
  publisher = {Verlag Dr. Otto Schmidt},
  address   = {K{\"o}ln},
  issn      = {1612-040X},
  pages     = {83 -- 88},
  year      = {2012},
  abstract  = {Mit seiner aktuellen Entscheidung (BGH v. 6.11.2011 - VIII ZR 340/10, MDR 2011, 1095 = MietRB MDR 2011, 337) hat der BGH die Darlegungs- und Beweislast f{\"u}r einen Verstoß gegen das Gebot der Wirtschaftlichkeit bei der Abrechnung von Betriebskosten konkretisiert. Der Beitrag erl{\"a}utert anhand der Hintergr{\"u}nde des Gebotes der Wirtschaftlichkeit die Konsequenzen f{\"u}r die Praxis.},
  language  = {de}
}
@incollection{Vismann2012,
  author    = {Vismann, Ulrich},
  title     = {Beton nach DIN 1045-2},
  series = {Wendehorst Bautechnische Zahlentafeln},
  booktitle = {Wendehorst Bautechnische Zahlentafeln},
  editor    = {Vismann, Ulrich},
  edition   = {34},
  publisher = {Vieweg + Teubner},
  address   = {Wiesbaden},
  isbn      = {978-3-8348-0960-5},
  doi       = {10.1007/978-3-8348-8613-2_11},
  pages     = {571 -- 600},
  year      = {2012},
  language  = {de}
}
@incollection{BorchertMichels2012,
  author    = {Borchert, J{\"o}rg and Michels, A.},
  title     = {Beschaffungsstrategien an der Schnittstelle Energiehandel / Vertrieb},
  series = {Energiehandel in Europa},
  booktitle = {Energiehandel in Europa},
  editor    = {Zenke, ines},
  edition   = {3. Aufl.},
  publisher = {Beck},
  address   = {M{\"u}nchen},
  isbn      = {978-3-406-63237-2},
  pages     = {508 -- 522},
  year      = {2012},
  language  = {de}
}
@book{MeskourisButenwegHolleretal.2012,
  author    = {Meskouris, Konstantin and Butenweg, Christoph and Holler, Stefan and Hake, Erwin},
  title     = {Baustatik in Beispielen},
  edition   = {2., bearb. Aufl.},
  publisher = {Springer},
  address   = {Heidelberg ; Dordrecht ; London ; New York},
  isbn      = {978-3-642-23529-0 (Print) ; 978-3-642-23530-6 (E-Book)},
  pages     = {XI, 431 S.},
  year      = {2012},
  language  = {de}
}
@article{SchubaHoefken2012,
  author    = {Schuba, Marko and H{\"o}fken, Hans},
  title     = {Backtrack5: Datensammlung und Reporterstellung f{\"u}r Pentester mit MagicTree / H{\"o}fken, Hans ; Schuba, Marko},
  series = {Hakin9. 73 (2012), H. 3},
  journal   = {Hakin9. 73 (2012), H. 3},
  publisher = {-},
  isbn      = {1733-7186},
  pages     = {12 -- 16},
  year      = {2012},
  language  = {de}
}
@article{Knueppel2012,
  author    = {Kn{\"u}ppel, Mark},
  title     = {Außerbilanzielle Korrekturen},
  series = {Handbuch der Bilanzierung online},
  journal   = {Handbuch der Bilanzierung online},
  editor    = {Federmann, Rudolf and Kußmaul, Heinz and M{\"u}ller, Stefan},
  publisher = {Haufe},
  address   = {Freiburg},
  issn      = {0172-0392},
  pages     = {Artikel HI 1380074},
  year      = {2012},
  language  = {de}
}
@article{KlingeWilkeMuehl2012,
  author    = {Klinge, Uwe and Wilke, Ralf and M{\"u}hl, Thomas},
  title     = {Auswahl der Herniennetze nach der "effektiven Porosit{\"a}t" - warum das Gewicht weniger wichtig ist},
  series = {Chirurgische Allgemeine : CHAZ ; Zeitung f{\"u}r Klinik und Praxis},
  volume    = {13},
  journal   = {Chirurgische Allgemeine : CHAZ ; Zeitung f{\"u}r Klinik und Praxis},
  number    = {12},
  publisher = {Kaden},
  address   = {Mannheim},
  isbn      = {1615-5378},
  pages     = {297 -- 301},
  year      = {2012},
  language  = {de}
}
@misc{TippkoetterPasteurMeyeretal.2012,
  author    = {Tippk{\"o}tter, Nils and Pasteur, A. and Meyer, C. and Kampeis, P. and Diller, R. and Ulber, Roland},
  title     = {Aufreinigung von Cephalosporin C durch por{\"o}se, selektiv-beschichtete Magnetpartikel},
  series = {Chemie Ingenieur Technik},
  volume    = {84},
  journal   = {Chemie Ingenieur Technik},
  number    = {8},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0009-286X},
  doi       = {10.1002/cite.201250391},
  pages     = {1369 -- 1370},
  year      = {2012},
  abstract  = {Die selektive Isolierung von Cephalosporin C (CPC) aus komplexen Fermentationssuspensionen unter Einsatz magnetischer Separation ist das Ziel dieser Arbeit. Das Verfahren wird im fr{\"u}hen Stadium der Aufarbeitung genutzt, um CPC zu stabilisieren und somit die Produktausbeute zu erh{\"o}hen. Als Adsorbersysteme f{\"u}r CPC wurden neben einem projektinternen magnetischen Material ND 10322, dessen Oberfl{\"a}chenladungen spezifisch f{\"u}r die Bindung des Zielmolek{\"u}ls synthetisiert wurden, verschiedene kommerzielle Partikelsysteme verglichen. Es konnten massenspezifische Maximalbeladungen von 51 mg g⁻¹ erreicht werden. Weiterhin wurde die Stabilit{\"a}t von CPC untersucht. Unter optimalen Adsorptionsbedingungen kann CPC stabilisiert werden, so dass die Geschwindigkeitskonstante der Degradation des b-Lactam-Rings unter diesen Bedingungen unter 0,005 h⁻¹ liegt. Untersuchungen zur Wiederverwertbarkeit der neuen Adsorbers zeigten eine irreversible Bindung geringer CPC-Mengen nach dem ersten Einsatz. Nach zw{\"o}lf Zyklen tritt eine irreversible Bindung von CPC ein, was zu einer signifikanten Reduktion der Adsorptionsf{\"a}higkeit f{\"u}hrt. Die Anh{\"a}ufung des CPC auf dem Adsorber konnte durch IR-Untersuchungen auf die Bildung einer Peptidbindung zwischen Carboxylgruppen des CPC und Aminogruppe der Adsorberoberfl{\"a}che zur{\"u}ckgef{\"u}hrt werden.},
  language  = {de}
}
@incollection{Borchert2012,
  author    = {Borchert, J{\"o}rg},
  title     = {Aufbau von Handelseinheiten},
  series = {Energiehandel in Europa},
  booktitle = {Energiehandel in Europa},
  editor    = {Zenke, Ines},
  edition   = {3. Aufl.},
  publisher = {Beck},
  address   = {M{\"u}nchen},
  isbn      = {978-3-406-63237-2},
  pages     = {467 -- 479},
  year      = {2012},
  language  = {de}
}
@inproceedings{BitzKraffOrzadaetal.2012,
  author    = {Bitz, Andreas and Kraff, O. and Orzada, S. and Maderwald, S. and Brote, I. and Johst, S. and Ladd, E.},
  title     = {Assessment of RF Safety of Transmit Coils at 7 Tesla by Experimental and Numerical Procedures (490.)},
  series = {19th annual ISMRM scientific meeting and exhibition 2011 : Montreal, Quebec, Canada, 7 - 13 May 2011},
  booktitle = {19th annual ISMRM scientific meeting and exhibition 2011 : Montreal, Quebec, Canada, 7 - 13 May 2011},
  number    = {Volume 1},
  publisher = {Curran},
  address   = {Red Hook, NY},
  isbn      = {978-1-61839-284-8},
  pages     = {475},
  year      = {2012},
  language  = {en}
}
@article{PaulssenKongArciszewskietal.2012,
  author    = {Paulßen, Elisabeth and Kong, Shushu and Arciszewski, Pawel and Wielbalck, Swantje and Abram, Ulrich},
  title     = {Aryl and NHC Compounds of Technetium and Rhenium},
  series = {Journal of the American Chemical Society},
  volume    = {134},
  journal   = {Journal of the American Chemical Society},
  number    = {22},
  publisher = {ACS Publications},
  address   = {Washington, DC},
  issn      = {1520-5126},
  doi       = {10.1021/ja3033718},
  pages     = {9118 -- 9121},
  year      = {2012},
  abstract  = {Air- and water-stable phenyl complexes with nitridotechnetium(V) cores can be prepared by straightforward procedures. [TcNPh2(PPh3)2] is formed by the reaction of [TcNCl2(PPh3)2] with PhLi. The analogous N-heterocyclic carbene (NHC) compound [TcNPh2(HLPh)2], where HLPh is 1,3,4-triphenyl-1,2,4-triazol-5-ylidene, is available from (NBu4)[TcNCl4] and HLPh or its methoxo-protected form. The latter compound allows the comparison of different Tc-C bonds within one compound. Surprisingly, the Tc chemistry with such NHCs does not resemble that of corresponding Re complexes, where CH activation and orthometalation dominate.},
  language  = {en}
}
@article{Wilke2012,
  author    = {Wilke, Thomas},
  title     = {Architekturzeichnung als Instrument der Theoriebildung. Lineamenta vs. Portraicture - Architekturdarstellung zwischen Wissenschaft und {\"O}ffentlichkeit. Tagung des DFG-Netzwerks-Schnittstelle Bild in Zusammenarbeit mit dem Lehrstuhl f{\"u}r Kunstgeschichte der Universit{\"a}t Regensburg, 28.4.2012.},
  series = {Kunstchronik},
  volume    = {65},
  journal   = {Kunstchronik},
  number    = {9/10},
  publisher = {Fachverlag Hans Carl},
  address   = {N{\"u}rnberg},
  issn      = {0023-5474},
  pages     = {494 -- 499},
  year      = {2012},
  language  = {de}
}
@article{PieperKlein2012,
  author    = {Pieper, Martin and Klein, Peter},
  title     = {Application of simple, periodic homogenization techniques to non-linear heat conduction problems in non-periodic, porous media},
  series = {Heat mass transfer},
  volume    = {48},
  journal   = {Heat mass transfer},
  number    = {2},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {0947-7411},
  doi       = {10.1007/s00231-011-0879-4},
  pages     = {291 -- 300},
  year      = {2012},
  abstract  = {Often, detailed simulations of heat conduction in complicated, porous media have large runtimes. Then homogenization is a powerful tool to speed up the calculations by preserving accurate solutions at the same time. Unfortunately real structures are generally non-periodic, which requires unpractical, complicated homogenization techniques. We demonstrate in this paper, that the application of simple, periodic techniques to realistic media, that are just close to periodic, gives accurate, approximative solutions. In order to obtain effective parameters for the homogenized heat equation, we have to solve a so called "cell problem". In contrast to periodic structures it is not trivial to determine a suitable unit cell, which represents a non-periodic media. To overcome this problem, we give a rule of thumb on how to choose a good cell. Finally we demonstrate the efficiency of our method for virtually generated foams as well as real foams and compare these results to periodic structures.},
  language  = {en}
}
@inproceedings{ReisgenSchleserAbdurakhmanovetal.2012,
  author    = {Reisgen, Uwe and Schleser, Markus and Abdurakhmanov, Aydemir and Gumenyuk, Andrej},
  title     = {Application of electron beam welding to fabrication of steel-aluminium dissimilar joint},
  series = {Beam technologies \& laser application : proceedings of the VII international conference, Saint Petersburg, Sept. 18-21, 2012},
  booktitle = {Beam technologies \& laser application : proceedings of the VII international conference, Saint Petersburg, Sept. 18-21, 2012},
  publisher = {Publ. House},
  address   = {Saint Petersburg},
  pages     = {265 -- 279},
  year      = {2012},
  language  = {en}
}
@inproceedings{FrotscherRaatschenStaat2012,
  author    = {Frotscher, Ralf and Raatschen, Hans-J{\"u}rgen and Staat, Manfred},
  title     = {Application of an edge-based smoothed finite element method on geometrically non-linear plates of non-linear material},
  series = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)},
  booktitle = {Proceedings European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012)},
  editor    = {Eberhardsteiner, J.},
  year      = {2012},
  language  = {en}
}
@incollection{BorggrafeOhndorfDachwaldetal.2012,
  author    = {Borggrafe, Andreas and Ohndorf, Andreas and Dachwald, Bernd and Seboldt, Wolfgang},
  title     = {Analysis of interplanetary solar sail trajectories with attitude dynamics},
  series = {Dynamics and Control of Space Systems 2012},
  booktitle = {Dynamics and Control of Space Systems 2012},
  publisher = {Univelt Inc},
  address   = {San Diego},
  isbn      = {978-0-87703-587-9},
  pages     = {1553 -- 1569},
  year      = {2012},
  abstract  = {We present a new approach to the problem of optimal control of solar sails for low-thrust trajectory optimization. The objective was to find the required control torque magnitudes in order to steer a solar sail in interplanetary space. A new steering strategy, controlling the solar sail with generic torques applied about the spacecraft body axes, is integrated into the existing low-thrust trajectory optimization software InTrance. This software combines artificial neural networks and evolutionary algorithms to find steering strategies close to the global optimum without an initial guess. Furthermore, we implement a three rotational degree-of-freedom rigid-body attitude dynamics model to represent the solar sail in space. Two interplanetary transfers to Mars and Neptune are chosen to represent typical future solar sail mission scenarios. The results found with the new steering strategy are compared to the existing reference trajectories without attitude dynamics. The resulting control torques required to accomplish the missions are investigated, as they pose the primary requirements to a real on-board attitude control system.},
  language  = {en}
}
@article{MuribTranCeunincketal.2012,
  author    = {Murib, Mohammed S. and Tran, Anh Quang and Ceuninck, Ward de and Sch{\"o}ning, Michael Josef and Nesladek, Milos and Serpeng{\"u}zel, Ali and Wagner, Patrick},
  title     = {Analysis of an optical biosensor based on elastic light scattering from diamond-, glass-, and sapphire microspheres},
  series = {Physica Status Solidi A},
  volume    = {209},
  journal   = {Physica Status Solidi A},
  number    = {9},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201100795},
  pages     = {1804 -- 1810},
  year      = {2012},
  abstract  = {Deoxyribonucleic acid (DNA) and protein recognition are now standard tools in biology. In addition, the special optical properties of microsphere resonators expressed by the high quality factor (Q-factor) of whispering gallery modes (WGMs) or morphology dependent resonances (MDRs) have attracted the attention of the biophotonic community. Microsphere-based biosensors are considered as powerful candidates to achieve label-free recognition of single molecules due to the high sensitivity of their WGMs. When the microsphere surface is modified with biomolecules, the effective refractive index and the effective size of the microsphere change resulting in a resonant wavelength shift. The transverse electric (TE) and the transverse magnetic (TM) elastic light scattering intensity of electromagnetic waves at 600 and 1400 nm are numerically calculated for DNA and unspecific binding of proteins to the microsphere surface. The effect of changing the optical properties was studied for diamond (refractive index 2.34), glass (refractive index 1.50), and sapphire (refractive index 1.75) microspheres with a 50 µm radius. The mode spacing, the linewidth of WGMs, and the shift of resonant wavelength due to the change in radius and refractive index, were analyzed by numerical simulations. Preliminary results of unspecific binding of biomolecules are presented. The calculated shift in WGMs can be used for biomolecules detection.},
  language  = {en}
}
@misc{StadtmuellerWollnyTippkoetteretal.2012,
  author    = {Stadtm{\"u}ller, R. and Wollny, S. and Tippk{\"o}tter, Nils and Ulber, Roland},
  title     = {Amplifikation und Einsatz von ssDNA-Aptameren},
  series = {Chemie Ingenieur Technik},
  volume    = {84},
  journal   = {Chemie Ingenieur Technik},
  number    = {8},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0009-286X},
  doi       = {10.1002/cite.201250112},
  pages     = {1294},
  year      = {2012},
  abstract  = {Die wachsende Produktpalette von z. B. Pharmazeutika geht mit einer steigenden Nachfrage f{\"u}r hochsensitive/schonende Aufreinigungstechniken einher. Bisherige Verfahren f{\"u}hren oft zu geringer Reinheit und verminderter Bioaktivit{\"a}t, zeigen eine Limitation der Analytengr{\"o}ße oder bedingen dessen Modifikation. Durch die Kombination von mikroskaligen Magnetpartikeln und spezifisch wechselwirkenden Einzelstrang-DNA-Oligonukleotiden, den sog. ssDNA-Aptameren, sind eine h{\"o}here Selektivit{\"a}t/Reinheit und eine Automatisierung m{\"o}glich. In diesem Kontext werden zum einen ssDNA-Amplifikationstechniken und zum anderen der praktische Einsatz von Aptameren in einer Magnetseparation vorgestellt. Die ssDNA-Synthese basiert auf einem In-vivo-dsDNA-Produktionsschritt mittels eines rekombinanten Escherichia coli. Die als High-copy-Plasmid organisierte Sequenz wird in vitro durch Kombination verschiedener enzymatischer Reaktionen in die funktionelle ssDNA {\"u}berf{\"u}hrt. Diese Technik bedingt nur minimale Instrumentierung bzw. Prozessregelung. Die zweite Synthesetechnik wird in Form eines In-vitro-Amplifikationsverfahrens realisiert und beruht auf dem Prinzip einer PCR (Potenzial zu einer Automatisierung bzw. Miniaturisierung). Die gewonnenen Aptamere werden im Anschluss in einem auf Magnetpartikeln basierten Trennverfahren zur Isolationvon 6xHis-tag-Proteinen bez{\"u}glich ihrer Eigenschaften untersucht.},
  language  = {de}
}
@misc{TippkoetterStaubSohlingetal.2012,
  author    = {Tippk{\"o}tter, Nils and Staub, C. and Sohling, U. and Ruf, N. and Ulber, Roland},
  title     = {Adsorptive Aufreinigung von Molkeproteinen},
  series = {Chemie Ingenieur Technik},
  volume    = {84},
  journal   = {Chemie Ingenieur Technik},
  number    = {8},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0009-286X},
  doi       = {10.1002/cite.201250395},
  pages     = {1285},
  year      = {2012},
  abstract  = {In der Molkeverarbeitung dominieren Membranfiltrationsverfahren die Prozessf{\"u}hrung. Hierbei werden {\"u}blicherweise Aufkonzentrierungen der Proteine und deren Trennung von dem Milchzucker Lactose durchgef{\"u}hrt. Der Prozess der adsorptiven Aufreinigung soll als kosteng{\"u}nstige Alternative zu den bisher gebr{\"a}uchlichen Verfahren dienen. Weiterhin er{\"o}ffnet sich durch das Verfahren die M{\"o}glichkeit, einzelne Proteinfraktionen w{\"a}hrend der Verarbeitung anzureichern. Als Proteinquellen wurden f{\"u}r die Untersuchungen Modellproteine, L{\"o}sungen aus Molkenproteinisolat, D{\"u}nnmolke und Molkekonzentrat verwendet. Die Eignung zur Proteinbindung wurden an Tonmaterialien, Silicaten und y-Aluminiumoxiden in Pulverform, in Form von Granulaten sowie Extrudaten als auch sph{\"a}rischen Partikeln {\"u}berpr{\"u}ft. Adsorbentien aus Bentonit/Silica und c-Aluminiumoxid k{\"o}nnen sowohl a-Lactalbumin (aLA) als auch b-Lactoglobulin (bLG) binden, wohingegen Materialien aus Siliciumoxid lediglich ein starkes Adsorptionsverhalten gegen{\"u}ber bLG zeigen. Mischmaterialien aus Siliciumoxid und a-Aluminiumoxid zeigen dasselbe Verhalten wie Materialien aus Siliciumoxid, weisen jedoch eine geringere Kapazit{\"a}t auf. Die Materialen wurden hinsichtlich ihres Einsatzes in chromatographischen Verfahren und Batch-Prozessen untersucht und ein Prozessentwurf f{\"u}r einen zweistufigen Batch-Prozess im R{\"u}hrkessel erarbeitet.},
  language  = {de}
}
@article{AtlasBrealeyDharetal.2012,
  author    = {Atlas, Glen and Brealey, David and Dhar, Sunil and Dikta, Gerhard and Singer, Meryvn},
  title     = {Additional hemodynamic measurements with an esophageal Doppler monitor: a preliminary report of compliance, force, kinetic energy, and afterload in the clinical setting},
  series = {Journal of clinical monitoring and computing},
  journal   = {Journal of clinical monitoring and computing},
  number    = {26},
  publisher = {Springer Nature},
  address   = {London},
  isbn      = {1573-2614},
  doi       = {10.1007/s10877-012-9386-5},
  pages     = {473 -- 482},
  year      = {2012},
  abstract  = {The esophageal Doppler monitor (EDM) is a minimally-invasive hemodynamic device which evaluates both cardiac output (CO), and fluid status, by estimating stroke volume (SV) and calculating heart rate (HR). The measurement of these parameters is based upon a continuous and accurate approximation of distal thoracic aortic blood flow. Furthermore, the peak velocity (PV) and mean acceleration (MA), of aortic blood flow at this anatomic location, are also determined by the EDM. The purpose of this preliminary report is to examine additional clinical hemodynamic calculations of: compliance (C), kinetic energy (KE), force (F), and afterload (TSVRi). These data were derived using both velocity-based measurements, provided by the EDM, as well as other contemporaneous physiologic parameters. Data were obtained from anesthetized patients undergoing surgery or who were in a critical care unit. A graphical inspection of these measurements is presented and discussed with respect to each patient's clinical situation. When normalized to each of their initial values, F and KE both consistently demonstrated more discriminative power than either PV or MA. The EDM offers additional applications for hemodynamic monitoring. Further research regarding the accuracy, utility, and limitations of these parameters is therefore indicated.},
  language  = {en}
}