@inproceedings{BaumannTeixeiraBouraGoettscheetal.2010,
  author    = {Baumann, Torsten and Teixeira Boura, Cristiano Jos{\´e} and G{\"o}ttsche, Joachim and Hoffschmidt, Bernhard and O'Connell, Bryan and Schmitz, Stefan and Zunft, Stefan},
  title     = {Air/Sand heat exchanger design and materials for solar thermal power plant applications},
  series = {SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France},
  booktitle = {SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France},
  publisher = {Soc. OSC},
  address   = {Saint Maur},
  pages     = {146 -- 147},
  year      = {2010},
  language  = {en}
}
@article{BaeckerPoghossianAbouzaretal.2010,
  author    = {B{\"a}cker, Matthias and Poghossian, Arshak and Abouzar, Maryam H. and Wenmackers, Sylvia and Janssens, Stoffel D. and Haenen, Ken and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Capacitive field-effect (bio-)chemical sensors based on nanocrystalline diamond films},
  series = {MRS Online Proceedings Library},
  volume    = {1203},
  journal   = {MRS Online Proceedings Library},
  publisher = {MRS},
  address   = {Warrendale},
  issn      = {1946-4274},
  year      = {2010},
  abstract  = {Capacitive field-effect electrolyte-diamond-insulator-semiconductor (EDIS) structures with O-terminated nanocrystalline diamond (NCD) as sensitive gate material have been realized and investigated for the detection of pH, penicillin concentration, and layer-by-layer adsorption of polyelectrolytes. The surface oxidizing procedure of NCD thin films as well as the seeding and NCD growth process on a Si-SiO2 substrate have been improved to provide high pH-sensitive, non-porous thin films without damage of the underlying SiO2 layer and with a high coverage of O-terminated sites. The NCD surface topography, roughness, and coverage of the surface groups have been characterized by SEM, AFM and XPS methods. The EDIS sensors with O-terminated NCD film treated in oxidizing boiling mixture for 45 min show a pH sensitivity of about 50 mV/pH. The pH-sensitive properties of the NCD have been used to develop an EDIS-based penicillin biosensor with high sensitivity (65-70 mV/decade in the concentration range of 0.25-2.5 mM penicillin G) and low detection limit (5 μM). The results of label-free electrical detection of layer-by-layer adsorption of charged polyelectrolytes are presented, too.},
  language  = {en}
}
@article{BegingMlynekHataihimakuletal.2010,
  author    = {Beging, Stefan and Mlynek, Daniela and Hataihimakul, Sudkanung and Poghossian, Arshak and Baldsiefen, Gerhard and Busch, Heinz and Laube, Norbert and Kleinen, Lisa and Sch{\"o}ning, Michael Josef},
  title     = {Field-effect calcium sensor for the determination of the risk of urinary stone formation},
  series = {Sensors and Actuators B: Chemical},
  volume    = {144},
  journal   = {Sensors and Actuators B: Chemical},
  number    = {2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2008.12.012},
  pages     = {374 -- 379},
  year      = {2010},
  abstract  = {Urinary stone formation has been evolved to a widespread disease during the last years. The reason for the formation of urinary stones are little crystals, mostly composed of calcium oxalate, which are formed in human kidneys. The early diagnosis of the risk for urinary stone formation of patients can be determined by the "Bonn-Risk-Index" method based on the potentiometric detection of the Ca2+-ion concentration and an optical determination of the triggered crystallisation of calcium oxalate in unprocessed urine. In this work, miniaturised capacitive field-effect EMIS (electrolyte-membrane-insulator-semiconductor) sensors have been developed for the determination of the Ca2+-ion concentration in human native urine. The Ca2+-sensitive EMIS sensors have been systematically characterised by impedance spectroscopy, capacitance-voltage and constant-capacitance method in terms of sensitivity, signal stability and response time in both CaCl2 solutions and in native urine. The obtained results demonstrate the suitability of EMIS sensors for the measurement of the Ca2+-ion concentration in native urine of patients.},
  language  = {en}
}
@article{ReisertHenkelSchneideretal.2010,
  author    = {Reisert, Steffen and Henkel, Hartmut and Schneider, Andreas and Sch{\"a}fer, Daniel and Friedrich, Peter and Berger, J{\"o}rg and Sch{\"o}ning, Michael Josef},
  title     = {Development of a handheld sensor system for the online measurement of hydrogen peroxide in aseptic filling systems},
  series = {Physica Status Solidi (A)},
  volume    = {207},
  journal   = {Physica Status Solidi (A)},
  number    = {4},
  publisher = {Wiley-VCH},
  address   = {Berlin},
  issn      = {1862-6300},
  doi       = {10.1002/pssa.200983304},
  pages     = {913 -- 918},
  year      = {2010},
  abstract  = {A handheld sensor system for the online measurement of hydrogen peroxide (H2O2) in aseptic sterilisation processes has been developed. It is based on a calorimetric-type gas sensor that consists of a differential set-up of two temperature sensors, of which one is catalytically activated and the second one is passivated and used as reference. The sensor principle relies in detecting a rise in temperature on the active sensor due to the exothermic reaction of H2O2 on the catalytic surface. To characterise the sensor system towards H2O2 sensitivity and other influencing factors, measurements have been carried out both at an experimental set-up and a manufacturer's sterilisation machine. Physical sensor characterisation was done by means of the optical microscopy.},
  language  = {en}
}
@article{MiyamotoSugawaraKanohetal.2010,
  author    = {Miyamoto, Ko-ichiro and Sugawara, Yuri and Kanoh, Shin´ichiro and Yoshinobu, Tatsuo and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Image correction method for the chemical imaging sensor},
  series = {Sensors and Actuators B: Chemical},
  volume    = {144},
  journal   = {Sensors and Actuators B: Chemical},
  number    = {2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0925-4005},
  doi       = {10.1016/j.snb.2008.10.069},
  pages     = {344 -- 348},
  year      = {2010},
  abstract  = {The chemical imaging sensor is a semiconductor-based chemical sensor that can visualize the spatial distribution of chemical species. For the practical application of this sensor, artifacts in the chemical images due to defects of the semiconductor substrate and contamination of the sensing surface etc. have been a major problem. An image correction method was developed to eliminate the influence of nonuniformity of individual sensor plate.},
  language  = {en}
}
@article{AbouzarPoghossianSiqueiraetal.2010,
  author    = {Abouzar, Maryam H. and Poghossian, Arshak and Siqueira, Jos{\´e} R. Jr. and Oliveira, Osvaldo N. Jr. and Moritz, Werner and Sch{\"o}ning, Michael Josef},
  title     = {Capacitive electrolyte-insulator-semiconductor structures functionalised with a polyelectrolyte/enzyme multilayer: New strategy for enhanced field-effect biosensing},
  series = {Physica Status Solidi (A)},
  volume    = {207},
  journal   = {Physica Status Solidi (A)},
  number    = {4},
  publisher = {Wiley-VCH},
  address   = {Berlin},
  issn      = {1862-6300},
  doi       = {10.1002/pssa.200983317},
  pages     = {884 -- 890},
  year      = {2010},
  abstract  = {A novel strategy for enhanced field-effect biosensing using capacitive electrolyte-insulator-semiconductor (EIS) structures functionalised with pH-responsive weak polyelectrolyte/enzyme or dendrimer/enzyme multilayers is presented. The feasibility of the proposed approach is exemplarily demonstrated by realising a penicillin biosensor based on a capacitive p-Si-SiO2 EIS structure functionalised with a poly(allylamine hydrochloride) (PAH)/penicillinase and a poly(amidoamine) dendrimer/penicillinase multilayer. The developed sensors response to changes in both the local pH value near the gate surface and the charge of macromolecules induced via enzymatic reaction, resulting in a higher sensitivity. For comparison, an EIS penicillin biosensor with adsorptively immobilised penicillinase has been also studied. The highest penicillin sensitivity of 100 mV/dec has been observed for the EIS sensor functionalised with the PAH/penicillinase multilayer. The lower and upper detection limit was around 20 µM and 10 mM, respectively. In addition, an incorporation of enzymes in a multilayer prepared by layer-by-layer technique provides a larger amount of immobilised enzymes per sensor area, reduces enzyme leaching effects and thus, enhances the biosensor lifetime (the loss of penicillin sensitivity after 2 months was 10-12\%).},
  language  = {en}
}
@article{SchoeningKirchnerNgetal.2010,
  author    = {Sch{\"o}ning, Michael Josef and Kirchner, Patrick and Ng, Yue Ann and Spelthahn, Heiko and Schneider, Andreas and Henkel, Hartmut and Friedrich, Peter and Kolstad, Jens and Berger, J{\"o}rg and Keusgen, Michael},
  title     = {Gas sensor investigation based on a catalytically activated thin-film thermopile for H2O2 detection},
  series = {Physica Status Solidi (A)},
  volume    = {207},
  journal   = {Physica Status Solidi (A)},
  number    = {4},
  publisher = {Wiley-VCH},
  address   = {Berlin},
  issn      = {1862-6300},
  doi       = {10.1002/pssa.200983309},
  pages     = {787 -- 792},
  year      = {2010},
  abstract  = {In aseptic filling systems, hydrogen peroxide vapour is commonly used for the reduction of microbial contaminations in carton packages. In this process, the germicidal efficiency of the vapour depends especially on the H₂O₂ concentration. To monitor the H₂O₂ concentration, a calorimetric H₂O₂ gas sensor based on a catalytically activated thin-film thermopile is investigated. Two different sensor layouts, namely a circular and a linear form, as well as two various material pairs such as tungsten/nickel and gold/nickel, have been examined for the realization of a thin-film thermopile. Additionally, manganese oxide and palladium particles have been compared as responsive catalysts towards H₂O₂. The thin-film sensors have been investigated at various H₂O₂ concentrations, gas temperatures and flow rates.},
  language  = {en}
}
@article{BuniatyanAbouzarMartirosyanetal.2010,
  author    = {Buniatyan, Vahe V. and Abouzar, Maryam H. and Martirosyan, Norayr W. and Schubert, J{\"u}rgen and Gevorgian, Spartak and Sch{\"o}ning, Michael Josef and Poghossian, Arshak},
  title     = {pH-sensitive properties of barium strontium titanate (BST) thin films prepared by pulsed laser deposition technique},
  series = {Physica Status Solidi (A)},
  volume    = {207},
  journal   = {Physica Status Solidi (A)},
  number    = {4},
  publisher = {Wiley-VCH},
  address   = {Berlin},
  issn      = {1862-6300},
  doi       = {10.1002/pssa.200983310},
  pages     = {824 -- 830},
  year      = {2010},
  abstract  = {pH-sensitive properties of barium strontium titanate (BST) high-k thin films as alternative gate material for field-effect capacitive (bio-)chemical sensors based on an electrolyte-insulator-semiconductor system have been investigated. The BST films of different compositions (Ba0.31Sr0.69TiO3, Ba0.25Sr0.75TiO3 and Mg-doped Ba0.8Sr0.2Mg0.1Ti0.9O3) were deposited by pulsed laser deposition technique from targets fabricated by self-propagating high-temperature synthesis. The realised sensors have been electrochemically characterised by means of impedance-spectroscopy, capacitance-voltage and constant-capacitance method. The sensors possess a Nernstian-like pH sensitivity in the concentration range between pH 3 and 11 with a response time of 5-10 s. An equivalent circuit model for the BST-based capacitive field-effect sensor is discussed.},
  language  = {en}
}
@article{TurekHeidenGuoetal.2010,
  author    = {Turek, Monik and Heiden, Wolfgang and Guo, Sharon and Riesen, Alfred and Schubert, J{\"u}rgen and Zander, Willi and Kr{\"u}ger, Peter and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Simultaneous detection of cyanide and heavy metals for environmental analysis by means of µISEs},
  series = {Physica Status Solidi (A)},
  volume    = {207},
  journal   = {Physica Status Solidi (A)},
  number    = {4},
  publisher = {Wiley-VCH},
  address   = {Berlin},
  issn      = {1862-6300},
  doi       = {10.1002/pssa.200983303},
  pages     = {817 -- 823},
  year      = {2010},
  abstract  = {In environmental analysis, cyanide and heavy metals play an important role, because these substances are highly toxic for biological systems. They can lead to chronic and acute diseases. Due to the chemical properties of cyanide it is frequently used for industrial processes such as extraction of silver and gold. Heavy metals can be found as trace elements in nature and are often applied in industries e.g., galvanization processes. Up to now, cyanide and heavy metals can be detected by several sensors separately and their detection is often limited to laboratory investigations. In this publication, with regard to an in situ analysis, a new miniaturized silicon-based sensor system for the simultaneous detection of cyanide and heavy metals in aqueous solutions is presented that is based on chalcogenide glass-based micro ion-selective electrodes (µISEs). The µISEs are incorporated into a specially designed measuring system for the simultaneous detection of heavy metals and cyanide in solutions and validated by simultaneous measurements of Cu2+- and CN--ions, Cd2+- and CN-- ions and Pb2+- and CN--ions. The particular sensor system has shown good sensor properties in the µ-molar ion-concentration range. For simultaneous measurements in complex heavy metal and cyanide solutions an intelligent software using fuzzy logic is discussed.},
  language  = {en}
}
@article{JansenBehbahaniLaumenetal.2010,
  author    = {Jansen, S. V. and Behbahani, Mehdi and Laumen, M. and Kaufmann, T. and Hormes, M. and Behr, Marek and Schmitz-Rode, T. and Steinseifer, U.},
  title     = {Investigation of Steady Flow Through a Realistic Model of the Thoracic Human Aorta Using 3D Stereo PIV and CFD-Simulation},
  series = {ASAIO Journal},
  volume    = {56},
  journal   = {ASAIO Journal},
  number    = {2},
  publisher = {Lippincott Williams \& Wilkins},
  address   = {Philadelphia},
  doi       = {10.1097/01.mat.0000369377.65122.a3},
  pages     = {98},
  year      = {2010},
  language  = {en}
}
@article{BehbahaniProbstMaietal.2010,
  author    = {Behbahani, Mehdi and Probst, M. and Mai, A. and Tran, L. and Vonderstein, K. and Keschenau, P. and Linde, T. and Steinseifer, U. and Behr, Marek and Mottaghy, K.},
  title     = {The influence of high shear on thrombosis and hemolysis in artificial organs},
  series = {The International Journal of Artificial Organs},
  volume    = {33},
  journal   = {The International Journal of Artificial Organs},
  number    = {7},
  publisher = {Sage},
  address   = {Thousand Oaks},
  issn      = {0391-3988},
  pages     = {426 -- 426},
  year      = {2010},
  language  = {en}
}
@article{SiqueiraBaeckerPoghossianetal.2010,
  author    = {Siqueira, Jos{\´e} R. Jr. and B{\"a}cker, Matthias and Poghossian, Arshak and Zucolotto, Valtencir and Oliveira, Osvaldo N. Jr. and Sch{\"o}ning, Michael Josef},
  title     = {Associating biosensing properties with the morphological structure of multilayers containing carbon nanotubes on field-effect devices},
  series = {Physica Status Solidi (A)},
  volume    = {207},
  journal   = {Physica Status Solidi (A)},
  number    = {4},
  publisher = {Wiley-VCH},
  address   = {Berlin},
  issn      = {1862-6300},
  doi       = {10.1002/pssa.200983301},
  pages     = {781 -- 786},
  year      = {2010},
  abstract  = {The control of molecular architecture provided by the layer-by-layer (LbL) technique has led to enhanced biosensors, in which advantageous features of distinct materials can be combined. Full optimization of biosensing performance, however, is only reached if the film morphology is suitable for the principle of detection of a specific biosensor. In this paper, we report a detailed morphology analysis of LbL films made with alternating layers of single-walled carbon nanotubes (SWNTs) and polyamidoamine (PAMAM) dendrimers, which were then covered with a layer of penicillinase (PEN). An optimized performance to detect penicillin G was obtained with 6-bilayer SWNT/PAMAM LbL films deposited on p-Si-SiO2-Ta2O5 chips, used in biosensors based on a capacitive electrolyte-insulator-semiconductor (EIS) and a light-addressable potentiometric sensor (LAPS) structure, respectively. Field-emission scanning electron microscopy (FESEM) and atomic force microscopy (AFM) images indicated that the LbL films were porous, with a large surface area due to interconnection of SWNT into PAMAM layers. This morphology was instrumental for the adsorption of a larger quantity of PEN, with the resulting LbL film being highly stable. The experiments to detect penicillin were performed with constant-capacitance (ConCap) and constant-current (CC) measurements for EIS and LAPS sensors, respectively, which revealed an enhanced detection signal and sensitivity of ca. 100 mV/decade for the field-effect sensors modified with the PAMAM/SWNT LbL film. It is concluded that controlling film morphology is essential for an enhanced performance of biosensors, not only in terms of sensitivity but also stability and response time.},
  language  = {en}
}
@article{NamAroraBehbahanietal.2010,
  author    = {Nam, J. and Arora, D. and Behbahani, Mehdi and Probst, M. and Benkowski, R. and Behr, Marek and Pasquali, M.},
  title     = {New computational method in hemolysis analysis for artificial heart pump},
  year      = {2010},
  language  = {en}
}
@article{UllrichGrottkeRossaintetal.2010,
  author    = {Ullrich, Sebastian and Grottke, Oliver and Rossaint, Rolf and Staat, Manfred and Deserno, Thomas M. and Kuhlen, Torsten},
  title     = {Virtual Needle Simulation with Haptics for Regional Anaesthesia},
  pages     = {3 Seiten},
  year      = {2010},
  language  = {en}
}
@article{RibitschKarlBirnerGruenbergeretal.2010,
  author    = {Ribitsch, Doris and Karl, Wolfgang and Birner-Gruenberger, R. and Gruber, K. and Eiteljoerg, I. and Remler, Peter and Wieland, S. and Siegert, Petra and Maurer, Karl-Heinz and Schwab, H.},
  title     = {C-terminal truncation of a metagenome-derived detergent protease for effective expression in E. coli},
  series = {Journal of biotechnology},
  volume    = {150},
  journal   = {Journal of biotechnology},
  number    = {3},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-4863 (E-Journal); 0168-1656 (Print)},
  doi       = {10.1016/j.jbiotec.2010.09.947},
  pages     = {408 -- 416},
  year      = {2010},
  abstract  = {Recently, a new alkaline protease named HP70 showing highest homology to extracellular serine proteases of Stenotrophomonas maltophilia and Xanthomonas campestris was found in the course of a metagenome screening for detergent proteases (Niehaus et al., submitted for publication). Attempts to efficiently express the enzyme in common expression hosts had failed. This study reports on the realization of overexpression in Escherichia coli after structural modification of HP70. Modelling of HP70 resulted in a two-domain structure, comprising the catalytic domain and a C-terminal domain which includes about 100 amino acids. On the basis of the modelled structure the enzyme was truncated by deletion of most of the C-terminal domain yielding HP70-C477. This structural modification allowed effective expression of active enzyme using E. coli BL21-Gold as the host. Specific activity of HP70-C477 determined with suc-l-Ala-l-Ala-l-Pro-l-Phe-p-nitroanilide as the substrate was 30 ± 5 U/mg compared to 8 ± 1 U/mg of the native enzyme. HP70-C477 was most active at 40 °C and pH 7-11; these conditions are prerequisite for a potential application as detergent enzyme. Determination of kinetic parameters at 40 °C and pH = 9.5 resulted in KM = 0.23 ± 0.01 mM and kcat = 167.5 ± 3.6 s⁻¹. MS-analysis of peptide fragments obtained from incubation of HP70 and HP70-C477 with insulin B indicated that the C-terminal domain influences the cleavage preferences of the enzyme. Washing experiments confirmed the high potential of HP70-C477 as detergent protease.},
  language  = {en}
}
@article{ProbstBehbahaniBorrmannetal.2010,
  author    = {Probst, M. and Behbahani, Mehdi and Borrmann, E. and Elgeti, S. and Nicolai, M. and Behr, Marek},
  title     = {Hemodynamic Modeling for Numerical Analysis and Design of Medical Devices},
  year      = {2010},
  language  = {en}
}
@article{BehbahaniMaiBergmannetal.2010,
  author    = {Behbahani, Mehdi and Mai, A. and Bergmann, B. and Waluga, C. and Behr, Marek and Tran, L. and Vonderstein, K. and Mottaghy, K.},
  title     = {Modeling and Numerical Simulation of Blood Damage},
  year      = {2010},
  language  = {en}
}
@article{BehbahaniProbstMaietal.2010,
  author    = {Behbahani, Mehdi and Probst, M. and Mai, A. and Behr, Marek and Tran, L. and Vonderstein, K. and Mottaghy, K.},
  title     = {Numerical Prediction of Blood Damage in Biomedical Devices},
  year      = {2010},
  language  = {en}
}
@misc{DieringerRenzLindeletal.2010,
  author    = {Dieringer, Matthias A. and Renz, Wolfgang and Lindel, Tomasz Dawid and Seifert, Frank and Frauenrath, Tobias and Waiczies, Helmar and von Knobelsdorff-Brenkhoff, Florian and Santoro, Davide and Hoffmann, Werner and Ittermann, Bernd and Schulz-Menger, Jeanette and Niendorf, Thoralf},
  title     = {4CH TX/RX Surface Coil for 7T: Design, Optimization and Application for Cardiac Function Imaging},
  series = {2010 ISMRM-ESMRMB joint annual meeting},
  journal   = {2010 ISMRM-ESMRMB joint annual meeting},
  issn      = {1545-4428},
  year      = {2010},
  abstract  = {Practical impediments of ultra high field cardiovascular MR (CVMR) can be catalogued in exacerbated magnetic field and radio frequency (RF) inhomogeneities, susceptibility and off-resonance effects, conductive and dielectric effects in tissue, and RF power deposition constraints, which all bear the potential to spoil the benefit of CVMR at 7T. Therefore, a four element cardiac transceive surface coil array was developed. Cardiac imaging provided clinically acceptable signal homogeneity with an excellent blood myocardium contrast. Subtle anatomic structures, such as pericardium, mitral and tricuspid valves and their apparatus, papillary muscles, and trabecles were accurately delineated.},
  language  = {en}
}
@misc{FrauenrathBeckerHezeletal.2010,
  author    = {Frauenrath, Tobias and Becker, Meike and Hezel, Fabian and Krombach, Gabriele A. and Kremer, Ute and Schulz-Menger, Jeanette and Niendorf, Thoralf},
  title     = {Comparison of Left Function Assessment Using Phonocardiogram and Electrocardiogram Triggered 2D SSFP CINE MR Imaging at 1.5 T and 3.0 T},
  series = {2010 ISMRM-ESMRMB joint annual meeting},
  journal   = {2010 ISMRM-ESMRMB joint annual meeting},
  issn      = {1545-4428},
  year      = {2010},
  abstract  = {As high-field cardiac MRI (CMR) becomes more widespread the propensity of ECG to distortions and mistriggering increases and with it the motivation for a cardiac triggering alternative. Hence, this study explores the suitability of acoustic cardiac triggering (ACT) for left ventricular (LV) function assessment in healthy subjects at 1.5T and 3.0T.},
  language  = {en}
}
@misc{HezelFrauenrathRenzetal.2010,
  author    = {Hezel, Fabian and Frauenrath, Tobias and Renz, Wolfgang and Schulz-Menger, Jeanette and Niendorf, Thoralf},
  title     = {Feasibility of CINE Myocardial T2* Mapping Using Susceptibility Weighted Gradient-Echo Imaging at 7.0 T},
  series = {2010 ISMRM-ESMRMB joint annual meeting},
  journal   = {2010 ISMRM-ESMRMB joint annual meeting},
  issn      = {1545-4428},
  year      = {2010},
  abstract  = {This study is designed to demonstrate the promise of susceptibility weighted 2D CINE FLASH and T2* Mapping of the heart at 7T.},
  language  = {en}
}