@article{LuftBalcBremen2024,
  author    = {Luft, Angela and Balc, Nicolae and Bremen, Sebastian},
  title     = {Experts' perspectives on the adoption of additive manufacturing in the industry and its interrelated implications in production structures},
  series = {Acta Technica Napocensis},
  volume    = {67},
  journal   = {Acta Technica Napocensis},
  number    = {1s},
  publisher = {Technical University of Cluj-Napoca},
  address   = {Cluj-Napoca},
  issn      = {1221-5872},
  pages     = {159 -- 168},
  year      = {2024},
  abstract  = {Additive Manufacturing (AM) is a topic that is becoming more relevant to many companies globally. With AM's progressive development and use for series production, integrating the technology into existing production structures is becoming an important criterion for businesses. This study qualitatively examines the actual state and different perspectives on the integration of AM in production structures. Seven semi-structured interviews were conducted and analyzed. The interview partners were high-level experts in Additive Manufacturing and production systems from industry and science. Four main themes were identified. Key findings are the far-reaching interrelationships and implications of AM within production structures. Specific AM-related aspects were identified. Those can be used to increase the knowledge and practical application of the technology in the industry and as a foundation for economic considerations.},
  language  = {en}
}
@article{LuftArntz2024,
  author    = {Luft, Nils and Arntz, Kristian},
  title     = {The impact and challenges of Industry 4.0 on factory design, organization and management},
  series = {Acta Technica Napocensis},
  volume    = {67},
  journal   = {Acta Technica Napocensis},
  number    = {1s},
  publisher = {Technical University of Cluj-Napoca},
  address   = {Cluj-Napoca},
  issn      = {1221-5872},
  pages     = {151 -- 158},
  year      = {2024},
  abstract  = {The fourth industrial revolution is on its way to reshape manufacturing and value creation in a profound way. The underlying technologies like cyber-physical systems (CPS), big data, collaborative robotics, additive manufacturing or artificial intelligence offer huge potentials for the optimization and evolution of production systems. However, many manufacturing companies struggle to implement these technologies. This can only in part be attributed to the lack of skilled personal within these companies or a missing digitalization strategy. Rather, there is a fundamental incompatibility between the way current production systems and companies (Industry 3.0) are structured across multiple dimensions compared to what is necessary for industry 4.0. This is especially true in manufacturing systems and their transition towards flexible, decentralized and autonomous value creation networks. This paper shows across various dimensions these incompatibilities within manufacturing systems, explores their reasons and discusses a different approach to create a foundation for Industry 4.0 in manufacturing companies.},
  language  = {en}
}
@article{AbbasBalcBremenetal.2024,
  author    = {Abbas, Karim and Balc, Nicolae and Bremen, Sebastian and Hedwig, Lukas},
  title     = {Polyetheretherketone (PEEK) in rapid tooling: advancements and applications for fused filament fabrication of rubber molds},
  series = {Acta Technica Napocensis},
  volume    = {67},
  journal   = {Acta Technica Napocensis},
  number    = {1s},
  publisher = {Technical University of Cluj-Napoca},
  address   = {Cluj-Napoca},
  issn      = {1221-5872},
  pages     = {13 -- 22},
  year      = {2024},
  abstract  = {Establishing high-performance polymers in additive manufacturing opens up new industrial applications. Polyetheretherketone (PEEK) was initially used in aerospace but is now widely applied in automotive, electronics, and medical industries. This study focuses on developing applications using PEEK and Fused Filament Fabrication for cost-efficient vulcanization injection mold production. A proof of concept confirms PEEK's suitability for AM mold making, withstanding vulcanization conditions. Printing PEEK above its glass transition temperature of 145 °C is preferable due to its narrow process window. A new process strategy at room temperature is discussed, with micrographs showing improved inter-layer bonding at 410°C nozzle temperature and 0.1 mm layer thickness. Minimizing the layer thickness from 0.15 mm to 0.1 mm improves tensile strength by 16\%.},
  language  = {en}
}
@article{EichlerBalcBremenetal.2024,
  author    = {Eichler, Fabian and Balc, Nicolae and Bremen, Sebastian and Schleser, Markus and Schwarz, Alexander},
  title     = {Research on reducing residual stresses of SLM parts made for downstream welding process},
  series = {Acta Technica Napocensis},
  volume    = {67},
  journal   = {Acta Technica Napocensis},
  number    = {1s},
  publisher = {Technical University of Cluj-Napoca},
  address   = {Cluj-Napoca},
  issn      = {1221-5872},
  pages     = {69 -- 78},
  year      = {2024},
  abstract  = {In the face of the current trend towards larger and more complex production tasks in the SLM process and the current limitations in terms of maximum build space, the welding of SLM components to each other or to conventionally manufactured parts is becoming increasingly relevant. The fusion welding of SLM components made of 316L has so far been rarely investigated and if so, then for highly specialised laser welding processes. When welding with industrial gas welding processes such as MIG/MAG or TIG welding, distortions occur which are associated with the resulting residual stresses in the components. This paper investigates process-side influencing factors to avoid resulting residual stresses in SLM components made of 316L. The aim is to develop a strategy to build up SLM components as stress-free as possible in order to join them as profitably as possible with a downstream welding process. For this purpose, influencing parameters such as laser power, scan speed, but also scan vector length and different scan patterns are investigated with regard to their influence on residual stresses.},
  language  = {en}
}
@article{ValeroFelderKrameretal.2024,
  author    = {Valero, Daniel and Felder, Stefan and Kramer, Matthias and Wang, Hang and Carrillo, Jos{\´e} M. and Pfister, Michael and Bung, Daniel},
  title     = {Air-water flows},
  series = {Journal of Hydraulic Research},
  volume    = {62},
  journal   = {Journal of Hydraulic Research},
  number    = {4},
  publisher = {Taylor \& Francis},
  issn      = {0022-1686 (Print)},
  doi       = {10.1080/00221686.2024.2379482},
  pages     = {319 -- 339},
  year      = {2024},
  abstract  = {High Froude-number open-channel flows can entrain significant volumes of air, a phenomenon that occurs continuously in spillways, in free-falling jets and in hydraulic jumps, or as localized events, notably at the toe of hydraulic jumps or in plunging jets. Within these flows, turbulence generates millions of bubbles and droplets as well as highly distorted wavy air-water interfaces. This phenomenon is crucial from a design perspective, as it influences the behaviour of high-velocity flows, potentially impairing the safety of dam operations. This review examines recent scientific and engineering progress, highlighting foundational studies and emerging developments. Notable advances have been achieved in the past decades through improved sampling of flows and the development of physics-based models. Current challenges are also identified for instrumentation, numerical modelling and (up)scaling that hinder the formulation of fundamental theories, which are instrumental for improving predictive models, able to offer robust support for the design of large hydraulic structures at prototype scale.},
  language  = {en}
}
@article{MyburghJacobszBothaLeRouxKotliaretal.2024,
  author    = {Myburgh-Jacobsz, Catharina Elizabeth and Botha-Le Roux, Shani and Kotliar, Konstantin and Wentzel, Annemarie and Jacobs, Adriaan and De Boever, Patrick and Goswami, Nandu and Strijdom, Hans and Smith, Wayne},
  title     = {Retinal vessel functional responses in South Africans living with and without HIV: the EndoAfrica-NWU study},
  series = {Microcirculation},
  journal   = {Microcirculation},
  number    = {Early View},
  publisher = {Wiley},
  address   = {Malden, MA},
  issn      = {1073-9688 (Print)},
  doi       = {10.1111/micc.12878},
  pages     = {11 Seiten},
  year      = {2024},
  language  = {en}
}
@article{FreyerKemptKloeser2024,
  author    = {Freyer, Nils and Kempt, Hendrik and Kl{\"o}ser, Lars},
  title     = {Easy-read and large language models: on the ethical dimensions of LLM-based text simplification},
  series = {Ethics and Information Technology},
  volume    = {26},
  journal   = {Ethics and Information Technology},
  publisher = {Springer},
  address   = {Dortrecht},
  issn      = {1388-1957 (Print)},
  doi       = {10.1007/s10676-024-09792-4},
  pages     = {10 Seiten},
  year      = {2024},
  abstract  = {The production of easy-read and plain language is a challenging task, requiring well-educated experts to write context-dependent simplifications of texts. Therefore, the domain of easy-read and plain language is currently restricted to the bare minimum of necessary information. Thus, even though there is a tendency to broaden the domain of easy-read and plain language, the inaccessibility of a significant amount of textual information excludes the target audience from partaking or entertainment and restricts their ability to live life autonomously. Large language models can solve a vast variety of natural language tasks, including the simplification of standard language texts to easy-read or plain language. Moreover, with the rise of generative models like GPT, easy-read and plain language may be applicable to all kinds of natural language texts, making formerly inaccessible information accessible to marginalized groups like, a.o., non-native speakers, and people with mental disabilities. In this paper, we argue for the feasibility of text simplification and generation in that context, outline the ethical dimensions, and discuss the implications for researchers in the field of ethics and computer science.},
  language  = {en}
}
@article{AkimbekovDigelZhubanovaetal.2024,
  author    = {Akimbekov, Nuraly and Digel, Ilya and Zhubanova, Azhar and Tastambek, Kuanysh T. and Tepecik, Atakan and Sherelkhan, Dinara},
  title     = {Biotechnological potentials of surfactants in coal utilization: a review},
  series = {Environmental Science and Pollution Research},
  volume    = {31},
  journal   = {Environmental Science and Pollution Research},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1614-7499},
  doi       = {10.1007/s11356-024-34892-5},
  pages     = {55099 -- 55118},
  year      = {2024},
  abstract  = {The quest for scientifically advanced and sustainable solutions is driven by growing environmental and economic issues associated with coal mining, processing, and utilization. Consequently, within the coal industry, there is a growing recognition of the potential of microbial applications in fostering innovative technologies. Microbial-based coal solubilization, coal beneficiation, and coal dust suppression are green alternatives to traditional thermochemical and leaching technologies and better meet the need for ecologically sound and economically viable choices. Surfactant-mediated approaches have emerged as powerful tools for modeling, simulation, and optimization of coal-microbial systems and continue to gain prominence in clean coal fuel production, particularly in microbiological co-processing, conversion, and beneficiation. Surfactants (surface-active agents) are amphiphilic compounds that can reduce surface tension and enhance the solubility of hydrophobic molecules. A wide range of surfactant properties can be achieved by either directly influencing microbial growth factors, stimulants, and substrates or indirectly serving as frothers, collectors, and modifiers in the processing and utilization of coal. This review highlights the significant biotechnological potential of surfactants by providing a thorough overview of their involvement in coal biodegradation, bioprocessing, and biobeneficiation, acknowledging their importance as crucial steps in coal consumption.},
  language  = {en}
}
@book{Heinrichs2024,
  author    = {Heinrichs, Florian},
  title     = {Algorithmen, Zufall, Unsicherheit - und Pizza!},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {978-3-662-69171-7 (Print)},
  doi       = {10.1007/978-3-662-69172-4},
  pages     = {X, 191 Seiten},
  year      = {2024},
  abstract  = {Dieses Buch l{\"a}dt dazu ein, die Welt um uns herum aus einem neuen Blickwinkel zu betrachten und dabei die spannende Verbindung zwischen der Mathematik und unserem t{\"a}glichen Leben zu entdecken - denn um die Technologien und Entwicklungen unserer modernen Gesellschaft zu verstehen, ben{\"o}tigen wir ein intuitives Verst{\"a}ndnis grundlegender mathematischer Ideen. In diesem Buch geht es um diese Grundlagen, vor allem aber um ihre praktische Anwendung im Alltag: Gemeinsam begeben wir uns auf eine unterhaltsame Reise und entdecken dabei, wie Mathematik in vielf{\"a}ltiger Weise allgegenw{\"a}rtig ist. Anschauliche Beispiele zeigen, wie wir t{\"a}glich - oft unbewusst - mathematische Ideen nutzen und wie wir mit Hilfe von Mathematik bessere Entscheidungen treffen k{\"o}nnen. Nach einer Einf{\"u}hrung in Algorithmen und Optimierungsprobleme, geht es im weiteren Verlauf um die Modellierung von Zufall und Unsicherheiten. Zum Ende des Buchs werden die Themen zusammengef{\"u}hrt und Algorithmen f{\"u}r Anwendungen besprochen, bei denen der Zufall eine entscheidende Rolle spielt.},
  language  = {de}
}
@article{AdelsThoennessenMonakhova2024,
  author    = {Adels, Klaudia and Th{\"o}nnessen, Vera and Monakhova, Yulia},
  title     = {Complementary instrumental techniques applied to pain relieving tablets in an undergraduate laboratory experiment},
  series = {Journal of Chemical Education},
  journal   = {Journal of Chemical Education},
  publisher = {ACS},
  issn      = {0021-9584 (Print)},
  doi       = {10.1021/acs.jchemed.4c00681},
  pages     = {11 Seiten},
  year      = {2024},
  abstract  = {Several unconnected laboratory experiments are usually offered for students in instrumental analysis lab. To give the students a more rational overview of the most common instrumental techniques, a new laboratory experiment was developed. Marketed pain relief drugs, familiar consumer products with one to three active components, namely, acetaminophen (paracetamol), acetylsalicylic acid (ASA), and caffeine, were selected. Common analytical methods were compared regarding the performance of qualitative and quantitative analysis of unknown tablets: UV-visible (UV-vis), infrared (IR), and nuclear magnetic resonance (NMR) spectroscopies, as well as high-performance liquid chromatography (HPLC). The students successfully uncovered the composition of formulations, which were divided into three difficulty categories. Students were shown that in addition to simple mixtures handled in theoretical classes, the composition of complex drug products can also be uncovered. By comparing the performance of different techniques, students deepen their understanding and compare the efficiency of analytical methods in the context of complex mixtures. The laboratory experiment can be adjusted for graduate level by including extra tasks such as method optimization, validation, and 2D spectroscopic techniques.},
  language  = {en}
}
@book{AlparAltBensbergetal.2023,
  author    = {Alpar, Paul and Alt, Rainer and Bensberg, Frank and Czarnecki, Christian},
  title     = {Anwendungsorientierte Wirtschaftsinformatik : Strategische Planung, Entwicklung und Nutzung von Informationssystemen},
  edition   = {10. Auflage},
  publisher = {Springer Vieweg},
  address   = {Wiesbaden},
  isbn      = {978-3-658-40351-5},
  doi       = {10.1007/978-3-658-40352-2},
  pages     = {XVIII, 557 Seiten},
  year      = {2023},
  abstract  = {Ein Lehrbuch f{\"u}r die anwendungsorientierte Seite der Wirtschaftsinformatik. Dieses Lehrbuch der Wirtschaftsinformatik ist vor allem eines: anwendungsorientiert. Nutzen Sie die zahlreichen Fallbeispiele, um die Kerninhalte des Fachgebiets zu erlernen und einen Einblick in die umfassenden Einsatzm{\"o}glichkeiten der Informationstechnologien zu gewinnen, die in Zeiten der Digitalisierung f{\"u}r Wirtschaft und Gesellschaft unverzichtbar sind. Von den Grundbegriffen der Informations- und Kommunikationstechnologie bis zur strategischen Planung, Nutzung und Entwicklung von Informationssystemen - dieses Buch bietet Ihnen alle Werkzeuge zur Integration neuer Konzepte in bestehende Softwarearchitekturen.},
  language  = {de}
}
@masterthesis{Peters2024,
  type      = {Bachelor Thesis},
  author    = {Peters, Carla},
  title     = {Display Neuke : Archivierte Perspektive},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {24 Seiten},
  year      = {2024},
  abstract  = {Die Website „Display Neuke" macht den bisher unver{\"o}ffentlichten Nachlass der Bildjournalistin Angela Neuke (1943-1997) aus der Sammlung des LVR-LandesMuseums Bonn digital und interaktiv zug{\"a}nglich. Das Projekt beleuchtet insbesondere Neukes Dokumentation der Frauenbewegung der 1970er Jahre in Westdeutschland und regt zur Reflexion {\"u}ber historische sowie aktuelle Frauenbilder an. Durch die bewusste Zusammenf{\"u}hrung und kontextuelle Einordnung des Materials wird sichtbar, wo, warum und unter welchen Umst{\"a}nden Fotostrecken und Magazinreportagen entstanden sind - das Archiv wird so als ein lebendiger Ort der Wissensvermittlung erfahrbar. Der Ansatz der programmierten und ver{\"o}ffentlichten Website erm{\"o}glicht es, Inhalte dynamisch anzupassen und zuk{\"u}nftig zu erweitern.},
  language  = {de}
}
@incollection{FerreinNikolovskiLimpertetal.2023,
  author    = {Ferrein, Alexander and Nikolovski, Gjorgji and Limpert, Nicolas and Reke, Michael and Schiffer, Stefan and Scholl, Ingrid},
  title     = {Controlling a Fleet of Autonomous LHD Vehicles in Mining Operation},
  series = {Multi-Robot Systems - New Advances},
  booktitle = {Multi-Robot Systems - New Advances},
  editor    = {K{\"u}{\c{c}}{\"u}k, Serdar},
  publisher = {Intech Open},
  address   = {London},
  isbn      = {978-1-83768-290-4},
  doi       = {10.5772/intechopen.113044},
  pages     = {21 Seiten},
  year      = {2023},
  abstract  = {In this chapter, we report on our activities to create and maintain a fleet of autonomous load haul dump (LHD) vehicles for mining operations. The ever increasing demand for sustainable solutions and economic pressure causes innovation in the mining industry just like in any other branch. In this chapter, we present our approach to create a fleet of autonomous special purpose vehicles and to control these vehicles in mining operations. After an initial exploration of the site we deploy the fleet. Every vehicle is running an instance of our ROS 2-based architecture. The fleet is then controlled with a dedicated planning module. We also use continuous environment monitoring to implement a life-long mapping approach. In our experiments, we show that a combination of synthetic, augmented and real training data improves our classifier based on the deep learning network Yolo v5 to detect our vehicles, persons and navigation beacons. The classifier was successfully installed on the NVidia AGX-Drive platform, so that the abovementioned objects can be recognised during the dumper drive. The 3D poses of the detected beacons are assigned to lanelets and transferred to an existing map.},
  language  = {de}
}
@misc{OPUS4-11152,
  title     = {Ordnung zur Aufhebung der Pr{\"u}fungsordnung f{\"u}r die Bachelorstudieng{\"a}nge „Smart Building Engineering", „Smart Building Engineering mit Praxissemester" und „Smart Building Engineering mit Auslandssemester"},
  organization    = {FH Aachen},
  pages     = {4 Seiten},
  year      = {2024},
  language  = {de}
}
@masterthesis{Celenk2024,
  type      = {Bachelor Thesis},
  author    = {Celenk, Mert Osman},
  title     = {Grafischer Aktivismus : Eine gestalterische Auseinandersetzung mit der Entwicklung einer visuellen Sprache f{\"u}r soziale Gerechtigkeit},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {386 Seiten},
  year      = {2024},
  abstract  = {Das Projekt "Grafischer Aktivismus" verortet sich im Schnittpunkt von Design und sozialem Engagement. Es ist eine gestalterische Auseinandersetzung, wie visuelle Kommunikation genutzt werden kann, um soziale Ungerechtigkeiten sichtbar zu machen und Bewusstsein zu schaffen. Durch die Entwicklung einer visuellen Sprache k{\"o}nnen Missst{\"a}nde thematisiert werden. Ziel ist es, durch gestalterische Mittel einen Dialog zu initiieren und die {\"o}ffentliche Wahrnehmung zu beeinflussen. Zu den Herangehensweisen geh{\"o}ren die Erstellung einer Schablone, die Entwicklung einer Schriftart und dessen Specimen. Diese Auseinandersetzung tr{\"a}gt dazu bei, gesellschaftliche Ver{\"a}nderungen anzustoßen und Gerechtigkeit zu f{\"o}rdern. Das Projekt bietet eine weitere Perspektive auf die Rolle von Grafikdesign im Aktivismus.},
  language  = {de}
}
@unpublished{BremmBlaneckBornheimetal.2024,
  author    = {Bremm, Florian and Blaneck, Patrick Gustav and Bornheim, Tobias and Grieger, Niklas and Bialonski, Stephan},
  title     = {Preprint: Detecting sexism in German online newspaper comments with open-source text embeddings},
  series = {arXiv},
  journal   = {arXiv},
  doi       = {10.48550/arXiv.2403.08592},
  pages     = {6 Seiten},
  year      = {2024},
  abstract  = {Sexism in online media comments is a pervasive challenge that often manifests subtly, complicating moderation efforts as interpretations of what constitutes sexism can vary among individuals. We study monolingual and multilingual open-source text embeddings to reliably detect sexism and misogyny in Germanlanguage online comments from an Austrian newspaper. We observed classifiers trained on text embeddings to mimic closely the individual judgements of human annotators. Our method showed robust performance in the GermEval 2024 GerMS-Detect Subtask 1 challenge, achieving an average macro F1 score of 0.597 (4th place, as reported on Codabench). It also accurately predicted the distribution of human annotations in GerMS-Detect Subtask 2, with an average Jensen-Shannon distance of 0.301 (2nd place). The computational efficiency of our approach suggests potential for scalable applications across various languages and linguistic contexts.},
  language  = {en}
}
@masterthesis{CarrenoPintaudi2024,
  type      = {Bachelor Thesis},
  author    = {Carreno Pintaudi, Delia},
  title     = {/SANO : Personal Well-Being - Eine mobile Anwendung zur Gesundheitsoptimierung und langfristigem Wohlbefinden},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {205 Seiten},
  year      = {2024},
  abstract  = {/SANO - eine App zur Gesundheitsoptimierung und langfristigem Wohlbefinden. In unserer schnelllebigen Welt f{\"u}hrt t{\"a}glicher Stress oft zur Vernachl{\"a}ssigung folgender Bereiche: Ern{\"a}hrung, Schlaf, Bewegung und Stress. Dieser Lebensstil f{\"o}rdert nicht {\"u}bertragbare Krankheiten wie Krebs, Herz-Kreislauf-Erkrankungen, Diabetes und chronische Atemwegserkrankungen, die weltweit viele Todesf{\"a}lle verursachen. Die Notwendigkeit umfassender L{\"o}sungen zur F{\"o}rderung gesunder Gewohnheiten wird immer dringlicher. /SANO unterst{\"u}tzt mit einem Werkzeug f{\"u}r Achtsamkeit und Gesundheit, das gesunde Gewohnheiten und Ziele definiert. Durch Tracking-M{\"o}glichkeiten, Routinen und To-Do-Listen werden sie individuell gef{\"o}rdert. Diese Arbeit stellt sich den Herausforderungen des aktuellen Krankheitszustandes unserer Gesellschaft und er{\"o}ffnet eine neue Perspektive im Well-Being und Gesundheitsbereich.},
  language  = {de}
}
@masterthesis{Russo2024,
  type      = {Bachelor Thesis},
  author    = {Russo, Jessica Rose},
  title     = {Ein lebendiger Ort : Eindr{\"u}cke aus dem Gemeinschaftsgarten HirschGr{\"u}n},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {95 Seiten},
  year      = {2024},
  abstract  = {Die interaktive Dokumentation erz{\"a}hlt die sinnliche Wirkung des Gemeinschaftsgartens HirschGr{\"u}n und teilt die Erfahrungen von vier G{\"a}rtner:innen in einer auditiven und visuellen Auseinandersetzung, innerhalb eines Open-World Ansatzes. Das Projekt stellt eine progressive Weise dar, sich mit journalistischen Inhalten zu besch{\"a}ftigen. Es schafft Perspektiven f{\"u}r die sozialen und sch{\"o}pferischen Potenziale eines Gemeinschaftsgartens. Interaktionen, visuelle und auditive Reize illustrieren die Atmosph{\"a}re. Gr{\"u}nfl{\"a}chen sind nicht nur klimarelevant, sondern schaffen f{\"u}r Stadtbewohner:innen vielf{\"a}ltige Wege, mit Leben in Kontakt zu treten. Besonders jene verbinden Gemeinschaft, Natur und Nachhaltigkeit. Die explorative Art technischer Informationsvermittlung und aktuelle Themen dieser Zeit werden auf einer Webseite vereint. Das Projekt zeigt eine Aussicht, multimedialen Journalismus zu gestalten.},
  language  = {de}
}
@incollection{HarlacherAltepostElsenetal.2024,
  author    = {Harlacher, Markus and Altepost, Andrea and Elsen, Ingo and Ferrein, Alexander and Hansen-Ampah, Adjan and Merx, Wolfgang and Niehues, Sina and Schiffer, Stefan and Shahinfar, Fatemeh Nasim},
  title     = {Approach for the identification of requirements on the design of AI-supported work systems (in problem-based projects)},
  series = {AI in Business and Economics},
  booktitle = {AI in Business and Economics},
  editor    = {Lausberg, Isabel and Vogelsang, Michael},
  publisher = {De Gruyter},
  address   = {Berlin},
  isbn      = {9783110790320},
  doi       = {10.1515/9783110790320},
  pages     = {87 -- 99},
  year      = {2024},
  abstract  = {To successfully develop and introduce concrete artificial intelligence (AI) solutions in operational practice, a comprehensive process model is being tested in the WIRKsam joint project. It is based on a methodical approach that integrates human, technical and organisational aspects and involves employees in the process. The chapter focuses on the procedure for identifying requirements for a work system that is implementing AI in problem-driven projects and for selecting appropriate AI methods. This means that the use case has already been narrowed down at the beginning of the project and must be completely defined in the following. Initially, the existing preliminary work is presented. Based on this, an overview of all procedural steps and methods is given. All methods are presented in detail and good practice approaches are shown. Finally, a reflection of the developed procedure based on the application in nine companies is given.},
  language  = {en}
}
@article{SanchezCespedesLeasureTejedorGaravitoetal.2023,
  author    = {Sanchez-Cespedes, Lina Maria and Leasure, Douglas Ryan and Tejedor-Garavito, Natalia and Amaya Cruz, Glenn Harry and Garcia Velez, Gustavo Adolfo and Mendoza Beltr{\´a}n, Andryu Enrique and Mar{\´i}n-Salazar, Yenny Andrea and Esch, Thomas and Tatem, Andrew J. and Ospina Boh{\´o}rquez, Mariana Francisca},
  title     = {Social cartography and satellite-derived building coverage for post-census population estimates in difficult-to-access regions of Colombia},
  series = {Population studies : a Journal of Demography},
  volume    = {78},
  journal   = {Population studies : a Journal of Demography},
  number    = {1},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1477-4747},
  doi       = {10.1080/00324728.2023.2190151},
  pages     = {3 -- 20},
  year      = {2023},
  abstract  = {Effective government services rely on accurate population numbers to allocate resources. In Colombia and globally, census enumeration is challenging in remote regions and where armed conflict is occurring. During census preparations, the Colombian National Administrative Department of Statistics conducted social cartography workshops, where community representatives estimated numbers of dwellings and people throughout their regions. We repurposed this information, combining it with remotely sensed buildings data and other geospatial data. To estimate building counts and population sizes, we developed hierarchical Bayesian models, trained using nearby full-coverage census enumerations and assessed using 10-fold cross-validation. We compared models to assess the relative contributions of community knowledge, remotely sensed buildings, and their combination to model fit. The Community model was unbiased but imprecise; the Satellite model was more precise but biased; and the Combination model was best for overall accuracy. Results reaffirmed the power of remotely sensed buildings data for population estimation and highlighted the value of incorporating local knowledge.},
  language  = {en}
}
@misc{Westhoff2024,
  type      = {Master Thesis},
  author    = {Westhoff, Lou-Mailin},
  title     = {Digitaler Marktplatz : f{\"u}r Erzeuger:innen und Konsument:innen regionaler Produkte},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {145 Seiten},
  year      = {2024},
  abstract  = {Digitaler Marktplatz f{\"u}r Erzeuger:innen und Verbraucher:innen regionaler Produkte. Das Ziel dieses Projekts ist es, solidarische Landwirtschaft (SoLaWi) zu digitalisieren, um eine zeitgem{\"a}ße Alternative zu den bestehenden Kauf- und Abonnementprozessen zu schaffen. Die dabei entstandene App „KoHof" erm{\"o}glicht landwirtschaftlichen Betrieben, sich online zu pr{\"a}sentieren, Abonnements zu verwalten und neue Mitglieder zu gewinnen. Gleichzeitig bietet die Plattform Verbraucher:innen eine unkomplizierte M{\"o}glichkeit, passende Betriebe und dazugeh{\"o}rige Produkte in der Region zu finden sowie ihre Mitgliedschaft zu verwalten. Insgesamt strebt das Projekt "KoHof" danach, die Solidarische Landwirtschaft digital zu transformieren und eine neue Perspektive f{\"u}r die regionale Erzeugung von Lebensmitteln zu er{\"o}ffnen. Durch diese innovative Plattform wird die Vernetzung zwischen Erzeugerinnen und Verbraucherinnen in der SoLaWi-Bewegung auf eine neue Stufe gehoben.},
  language  = {de}
}
@misc{Kaiser2024,
  type      = {Master Thesis},
  author    = {Kaiser, Leonie},
  title     = {Der Konflikt von Konsum und Minimalismus : die Beziehung zu unseren Dingen und ihre Rolle im Wohnraum},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {137 Seiten},
  year      = {2024},
  abstract  = {Das Thema der Masterarbeit erl{\"a}utert den Konflikt zwischen Konsum und Minimalismus. {\"U}berkonsum und Minimalismus sind gegens{\"a}tzliche Extreme. Durch die Beziehung zwischen Mensch und Objekt lassen sich die beiden Gegens{\"a}tze vereinen. Die Konzentration auf nur wenige Objekte hat eine Reduktion des Konsums und eine Fokussierung auf wenige Objekte zur Folge. Das Konzept „kubo" gibt Objekten einen Raum. Das Regal „kubo" ist mit verstellbaren Regalb{\"o}den ausgestattet. So k{\"o}nnen die Gegenst{\"a}nde individuell platziert werden. Das Verstellen und Anordnen der Regalb{\"o}den k{\"o}nnen Benutzer:innen nach eigenem Belieben vornehmen. Die Objekte werden im Regal hervorgehoben. Sie erhalten dadurch mehr Aufmerksamkeit. Ziel ist es, dass der Benutzer:innen mehr mit den Objekten interagieren und sich bewusst werden, was wirklich wichtig ist. „kubo" versucht dem Problem des {\"U}berkonsums entgegenzuwirken. Durch die Hervorhebung wichtiger Objekte wird das Bewusstsein f{\"u}r den eigenen Konsum gesch{\"a}rft.},
  language  = {de}
}
@misc{Breuer2024,
  type      = {Master Thesis},
  author    = {Breuer, Annika},
  title     = {Climate Engineering : Entwicklung einer digitalen Plattform f{\"u}r Climate Engineering Maßnahmen},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {131 Seiten},
  year      = {2024},
  abstract  = {Dieses Projekt hat zum Ziel, umfassend {\"u}ber Climate Engineering-Maßnahmen zu informieren und dabei insbesondere ihre Funktionsweise, Kosten und Risiken darzustellen. Die entstandene Plattform "Die Erde abk{\"u}hlen!" bietet einen Einblick in die L{\"o}sungsans{\"a}tze des Climate Engineerings durch die Verwendung von Storytelling. Sie erm{\"o}glicht Nutzer:innen einen {\"U}berblick {\"u}ber den aktuellen Stand der Klimaerw{\"a}rmung sowie den Vergleich von Climate Engineering-Maßnahmen. Ein entwickeltes Bewertungssystem auf Grundlage der "Royal Society" sowie interaktive Infografiken geben Nutzer:innen einen umfassenden Einblick. Das Hauptziel des Projekts ist die digitale Transformation der Climate Engineering-L{\"o}sungsans{\"a}tze. Dabei geht es nicht nur darum, {\"u}ber die Folgen der Klimaerw{\"a}rmung zu informieren, sondern auch konkrete L{\"o}sungen aufzuzeigen. Durch die Entwicklung eines innovativen Storytellings wird die Thematik nicht nur dramaturgisch pr{\"a}sentiert, sondern erm{\"o}glicht es den Nutzer:innen auch, ihre eigene Wissensvertiefung zu steuern.},
  language  = {de}
}
@misc{Beyer2024,
  type      = {Master Thesis},
  author    = {Beyer, Laura},
  title     = {Die Stuhl - und Sichtbarkeit von Gestalterinnen : ein Atlas {\"u}ber Frauen im Stuhldesign},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {493 Seiten},
  year      = {2024},
  abstract  = {Das Masterprojekt DIE STUHL hebt die Unsichtbarkeit von Gestalterinnen im Stuhldesign hervor. Es werden 108 Designerinnen aus 40 L{\"a}ndern vorgestellt, die vom Beginn des 20. Jahrhunderts bis heute innovative und richtungsweisende Entw{\"u}rfe von St{\"u}hlen entwickelt haben. Die Arbeit beleuchtet den Beitrag, den sie geleistet haben und stellt gleichzeitig heraus, dass viele von ihnen im internationalen Designkanon {\"u}bersehen wurden. Chronologisch nach dem Erscheinungsjahr der ersten entwickelten St{\"u}hle geordnet, werden die Objekte in einem Atlas illustriert und Kurzbiografien der Protagonistinnen gezeigt. Anhand von Informationsgrafiken werden die St{\"u}hle in das soziopolitische Geschehen ihrer Zeit eingebettet. DIE STUHL w{\"u}rdigt die Arbeit von Gestalterinnen und stellt Fragen zur strukturellen Ungleichheit der Geschlechter. Parallel zur Publikation ist außerdem eine Skulptur entstanden, die als Zeitstrahl fungiert und in abstrakter Form alle im Atlas erw{\"a}hnten St{\"u}hle auff{\"u}hrt. Hierbei wird das ungleiche Verh{\"a}ltnis der von Gestalterinnen und Gestalter entworfenen St{\"u}hle sichtbar.},
  language  = {de}
}
@misc{Lux2024,
  type      = {Master Thesis},
  author    = {Lux, Anneli},
  title     = {Konzeption und Gestaltung einer Applikation zur F{\"o}rderung der individuellen Lehre an Schulen},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {327 Seiten},
  year      = {2024},
  abstract  = {Die Abschlussarbeit thematisiert konzeptionelle M{\"o}glichkeiten f{\"u}r die Unterst{\"u}tzung in der Lehre. Lehrkr{\"a}fte erfahren eine hohe Auslastung in ihrem Beruf. Besonders ein wachsender Fachkr{\"a}ftemangel verst{\"a}rkt das Problem, welches wiederum Auswirkungen auf die Leistungen der Sch{\"u}lerinnen und Sch{\"u}ler haben kann. Somit kann auch der individuellen F{\"o}rderung nicht ausreichend nachgegangen werden. Die L{\"o}sung der Arbeit ist Kinvi, ein digitaler KI-Lehrassistent. Kinvi soll leistungsschwache und leistungsstarke Sch{\"u}ler f{\"o}rdern. Dabei kann Kinvi Inhalte erkl{\"a}ren, eine individuelle Lernstruktur vorgeben und sogar {\"U}bungen erstellen. Auch spielerische Inhalte und ein motivierendes Feedback sind inbegriffen. Lehrkr{\"a}fte k{\"o}nnen Inhalte KI gest{\"u}tzt steuern und Leistungen {\"u}berblicken. Dies soll zur Entlastung der Lehrkr{\"a}fte f{\"u}hren und die F{\"a}higkeiten der Sch{\"u}lerinnen und Sch{\"u}ler gezielt f{\"o}rdern.},
  language  = {de}
}
@masterthesis{Walossek2024,
  type      = {Bachelor Thesis},
  author    = {Waloßek, Marvin},
  title     = {RehaGlove : Exoskelett zur Griffunterst{\"u}tzung bei rheumatoider Arthritis oder Arthrose.},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {132 Seiten},
  year      = {2024},
  abstract  = {RehaGlove ist ein Exoskelett, dass Menschen mit rheumatoider Arthritis oder Arthrose bei der Bew{\"a}ltigung des Alltags helfen soll. Die rheumatoide Arthritis zeichnet sich vorwiegend durch die chronischen Entz{\"u}ndungen des Gelenkapparats aus, w{\"a}hrend die Arthrose eine alters- oder belastungsinduzierte Degeneration des Gelenkgewebes darstellt. Bei beiden Erkrankungen sind die Fingergelenke besonders h{\"a}ufig betroffen. Es kommt zu sehr starken Schmerzen, Bewegungseinschr{\"a}nkungen und Kraftverlust. Da wir unsere H{\"a}nde jedoch t{\"a}glich brauchen, gestaltet sich der Alltag mit einer solch einschr{\"a}nkenden Krankheit als besonders schmerzhaft. Dabei soll RehaGlove Abhilfe schaffen. Mehrere Zug-/ Druck-Kabel unterst{\"u}tzen den Griff und steigern die Griffkraft. Außerdem erm{\"o}glichen sie die eigenst{\"a}ndige Ausf{\"u}hrung physiotehrapeutischer Aufgaben und erleichtern es die Gelenke mobil zu halten.},
  language  = {de}
}
@article{VarrialeHengsbachGuoetal.2024,
  author    = {Varriale, Ludovica and Hengsbach, Jan-Niklas and Guo, Tianyi and Kuka, Katrin and Tippk{\"o}tter, Nils and Ulber, Roland},
  title     = {Sustainable production of lactic acid using a perennial ryegrass as feedstock—a comparative study of fermentation at the bench- and reactor-scale, and ensiling},
  series = {Sustainability},
  volume    = {16},
  journal   = {Sustainability},
  number    = {18},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2071-1050},
  doi       = {10.3390/su16188054},
  year      = {2024},
  abstract  = {Perennial ryegrass (Lolium perenne) is an underutilized lignocellulosic biomass that has several benefits such as high availability, renewability, and biomass yield. The grass press-juice obtained from the mechanical pretreatment can be used for the bio-based production of chemicals. Lactic acid is a platform chemical that has attracted consideration due to its broad area of applications. For this reason, the more sustainable production of lactic acid is expected to increase. In this work, lactic acid was produced using complex medium at the bench- and reactor scale, and the results were compared to those obtained using an optimized press-juice medium. Bench-scale fermentations were carried out in a pH-control system and lactic acid production reached approximately 21.84 ± 0.95 g/L in complex medium, and 26.61 ± 1.2 g/L in press-juice medium. In the bioreactor, the production yield was 0.91 ± 0.07 g/g, corresponding to a 1.4-fold increase with respect to the complex medium with fructose. As a comparison to the traditional ensiling process, the ensiling of whole grass fractions of different varieties harvested in summer and autumn was performed. Ensiling showed variations in lactic acid yields, with a yield up to 15.2\% dry mass for the late-harvested samples, surpassing typical silage yields of 6-10\% dry mass.},
  language  = {en}
}
@article{OrtnerHauserSchmadereretal.2019,
  author    = {Ortner, Marion and Hauser, Christine and Schmaderer, Christoph and Muggenthaler, Claudia and Hapfelmeier, Alexander and Sorg, Christian and Diehl-Schmid, Janine and Kurz, Alexander and F{\"o}rstl, Hans and Ikenberg, Benno and Kotliar, Konstantin and Holger, Poppert and Grimmer, Timo},
  title     = {Decreased vascular pulsatility in Alzheimer's disease dementia measured by transcranial color-coded duplex sonography},
  series = {Neuropsychiatric disease and treatment},
  journal   = {Neuropsychiatric disease and treatment},
  number    = {15},
  publisher = {Dove Medical Press},
  address   = {Albany, Auckland},
  issn      = {1178-2021},
  doi       = {10.2147/NDT.S225754},
  pages     = {3487 -- 3499},
  year      = {2019},
  abstract  = {Purpose: Impaired paravascular drainage of β-Amyloid (Aβ) has been proposed as a contributing cause for sporadic Alzheimer's disease (AD), as decreased cerebral blood vessel pulsatility and subsequently reduced propulsion in this pathway could lead to the accumulation and deposition of Aβ in the brain. Therefore, we hypothesized that there is an increased impairment in pulsatility across AD spectrum. Patients and Methods: Using transcranial color-coded duplex sonography (TCCS) the resistance and pulsatility index (RI; PI) of the middle cerebral artery (MCA) in healthy controls (HC, n=14) and patients with AD dementia (ADD, n=12) were measured. In a second step, we extended the sample by adding patients with mild cognitive impairment (MCI) stratified by the presence (MCI-AD, n=8) or absence of biomarkers (MCI-nonAD, n=8) indicative for underlying AD pathology, and compared RI and PI across the groups. To control for atherosclerosis as a confounder, we measured the arteriolar-venular-ratio of retinal vessels. Results: Left and right RI (p=0.020; p=0.027) and left PI (p=0.034) differed between HC and ADD controlled for atherosclerosis with AUCs of 0.776, 0.763, and 0.718, respectively. The RI and PI of MCI-AD tended towards ADD, of MCI-nonAD towards HC, respectively. RIs and PIs were associated with disease severity (p=0.010, p=0.023). Conclusion: Our results strengthen the hypothesis that impaired pulsatility could cause impaired amyloid clearance from the brain and thereby might contribute to the development of AD. However, further studies considering other factors possibly influencing amyloid clearance as well as larger sample sizes are needed.},
  language  = {en}
}
@article{BandlitzNakhoulKotliar2022,
  author    = {Bandlitz, Stefan and Nakhoul, Makram and Kotliar, Konstantin},
  title     = {Daily variations of corneal white-to-white diameter measured with different methods},
  series = {Clinical and experimental optometry},
  journal   = {Clinical and experimental optometry},
  number    = {14},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {0816-4622},
  doi       = {10.2147/OPTO.S360651},
  pages     = {173 -- 181},
  year      = {2022},
  abstract  = {Purpose: A precise determination of the corneal diameter is essential for the diagnosis of various ocular diseases, cataract and refractive surgery as well as for the selection and fitting of contact lenses. The aim of this study was to investigate the agreement between two automatic and one manual method for corneal diameter determination and to evaluate possible diurnal variations in corneal diameter. Patients and Methods: Horizontal white-to-white corneal diameter of 20 volunteers was measured at three different fixed times of a day with three methods: Scheimpflug method (Pentacam HR, Oculus), placido based topography (Keratograph 5M, Oculus) and manual method using an image analysis software at a slitlamp (BQ900, Haag-Streit). Results: The two-factorial analysis of variance could not show a significant effect of the different instruments (p = 0.117), the different time points (p = 0.506) and the interaction between instrument and time point (p = 0.182). Very good repeatability (intraclass correlation coefficient ICC, quartile coefficient of dispersion QCD) was found for all three devices. However, manual slitlamp measurements showed a higher QCD than the automatic measurements with the Keratograph 5M and the Pentacam HR at all measurement times. Conclusion: The manual and automated methods used in the study to determine corneal diameter showed good agreement and repeatability. No significant diurnal variations of corneal diameter were observed during the period of time studied.},
  language  = {en}
}
@article{KnoedlerRuehlEmontsetal.2019,
  author    = {Kn{\"o}dler, Matthias and R{\"u}hl, Clemens and Emonts, Jessica and Buyel, Johannes Felix},
  title     = {Seasonal weather changes affect the yield and quality of recombinant proteins produced in transgenic tobacco plants in a greenhouse setting},
  series = {Frontiers in Plant Science},
  journal   = {Frontiers in Plant Science},
  number    = {10},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {1664-462X (online-ressource)},
  doi       = {10.3389/fpls.2019.01245},
  pages     = {13 Seiten},
  year      = {2019},
  abstract  = {Transgenic plants have the potential to produce recombinant proteins on an agricultural scale, with yields of several tons per year. The cost-effectiveness of transgenic plants increases if simple cultivation facilities such as greenhouses can be used for production. In such a setting, we expressed a novel affinity ligand based on the fluorescent protein DsRed, which we used as a carrier for the linear epitope ELDKWA from the HIV-neutralizing antibody 2F5. The DsRed-2F5-epitope (DFE) fusion protein was produced in 12 consecutive batches of transgenic tobacco (Nicotiana tabacum) plants over the course of 2 years and was purified using a combination of blanching and immobilized metal-ion affinity chromatography (IMAC). The average purity after IMAC was 57 ± 26\% (n = 24) in terms of total soluble protein, but the average yield of pure DFE (12 mg kg-1) showed substantial variation (± 97 mg kg-1, n = 24) which correlated with seasonal changes. Specifically, we found that temperature peaks (>28°C) and intense illuminance (>45 klx h-1) were associated with lower DFE yields after purification, reflecting the loss of the epitope-containing C-terminus in up to 90\% of the product. Whereas the weather factors were of limited use to predict product yields of individual harvests conducted for each batch (spaced by 1 week), the average batch yields were well approximated by simple linear regression models using two independent variables for prediction (illuminance and plant age). Interestingly, accumulation levels determined by fluorescence analysis were not affected by weather conditions but positively correlated with plant age, suggesting that the product was still expressed at high levels, but the extreme conditions affected its stability, albeit still preserving the fluorophore function. The efficient production of intact recombinant proteins in plants may therefore require adequate climate control and shading in greenhouses or even cultivation in fully controlled indoor farms.},
  language  = {en}
}
@phdthesis{Emonts2013,
  author    = {Emonts, Jessica},
  title     = {Searching for many defective edges in hypergraphs},
  publisher = {Rheinisch-Westf{\"a}lischen Technischen Hochschule Aachen},
  address   = {Aachen},
  pages     = {VIII, 104 Seiten : Ill.},
  year      = {2013},
  language  = {en}
}
@article{BernauKnoedlerEmontsetal.2022,
  author    = {Bernau, C. R. and Kn{\"o}dler, Matthias and Emonts, Jessica and J{\"a}pel, Ronald Colin and Buyel, Johannes Felix},
  title     = {The use of predictive models to develop chromatography-based purification processes},
  series = {Frontiers in Bioengineering and Biotechnology},
  journal   = {Frontiers in Bioengineering and Biotechnology},
  number    = {10},
  publisher = {Frontiers Media},
  address   = {Lausanne},
  issn      = {2296-4185 (online-ressource)},
  doi       = {10.3389/fbioe.2022.1009102},
  pages     = {25 Seiten},
  year      = {2022},
  abstract  = {Chromatography is the workhorse of biopharmaceutical downstream processing because it can selectively enrich a target product while removing impurities from complex feed streams. This is achieved by exploiting differences in molecular properties, such as size, charge and hydrophobicity (alone or in different combinations). Accordingly, many parameters must be tested during process development in order to maximize product purity and recovery, including resin and ligand types, conductivity, pH, gradient profiles, and the sequence of separation operations. The number of possible experimental conditions quickly becomes unmanageable. Although the range of suitable conditions can be narrowed based on experience, the time and cost of the work remain high even when using high-throughput laboratory automation. In contrast, chromatography modeling using inexpensive, parallelized computer hardware can provide expert knowledge, predicting conditions that achieve high purity and efficient recovery. The prediction of suitable conditions in silico reduces the number of empirical tests required and provides in-depth process understanding, which is recommended by regulatory authorities. In this article, we discuss the benefits and specific challenges of chromatography modeling. We describe the experimental characterization of chromatography devices and settings prior to modeling, such as the determination of column porosity. We also consider the challenges that must be overcome when models are set up and calibrated, including the cross-validation and verification of data-driven and hybrid (combined data-driven and mechanistic) models. This review will therefore support researchers intending to establish a chromatography modeling workflow in their laboratory.},
  language  = {en}
}
@article{EmontsBuyel2023,
  author    = {Emonts, Jessica and Buyel, Johannes Felix},
  title     = {An overview of descriptors to capture protein properties - Tools and perspectives in the context of QSAR modeling},
  series = {Computational and Structural Biotechnology Journal},
  journal   = {Computational and Structural Biotechnology Journal},
  number    = {21},
  publisher = {Research Network of Computational and Structural Biotechnology},
  address   = {Gotenburg},
  issn      = {2001-0370 (online-ressource)},
  doi       = {10.1016/j.csbj.2023.05.022},
  pages     = {3234 -- 3247},
  year      = {2023},
  abstract  = {Proteins are important ingredients in food and feed, they are the active components of many pharmaceutical products, and they are necessary, in the form of enzymes, for the success of many technical processes. However, production can be challenging, especially when using heterologous host cells such as bacteria to express and assemble recombinant mammalian proteins. The manufacturability of proteins can be hindered by low solubility, a tendency to aggregate, or inefficient purification. Tools such as in silico protein engineering and models that predict separation criteria can overcome these issues but usually require the complex shape and surface properties of proteins to be represented by a small number of quantitative numeric values known as descriptors, as similarly used to capture the features of small molecules. Here, we review the current status of protein descriptors, especially for application in quantitative structure activity relationship (QSAR) models. First, we describe the complexity of proteins and the properties that descriptors must accommodate. Then we introduce descriptors of shape and surface properties that quantify the global and local features of proteins. Finally, we highlight the current limitations of protein descriptors and propose strategies for the derivation of novel protein descriptors that are more informative.},
  language  = {en}
}
@book{Heuermann2024,
  author    = {Heuermann, Holger},
  title     = {Microwave technology: field simulation, non-linear circuit technology, components and subsystems, plasma technology, antennas and propagation},
  publisher = {Springer},
  address   = {Wiesbaden},
  isbn      = {978-3-658-45685-6},
  doi       = {10.1007/978-3-658-45686-3},
  pages     = {XII, 391 Seiten},
  year      = {2024},
  abstract  = {The book covers various numerical field simulation methods, nonlinear circuit technology and its MF-S- and X-parameters, as well as state-of-the-art power amplifier techniques. It also describes newly presented oscillators and the emerging field of GHz plasma technology. Furthermore, it addresses aspects such as waveguides, mixers, phase-locked loops, antennas, and propagation effects, in combination with the bachelor's book 'High-Frequency Engineering,' encompassing all aspects related to the current state of GHz technology.},
  language  = {en}
}
@misc{BrotsackPettrak2014,
  author    = {Brotsack, Raimund and Pettrak, J{\"u}rgen},
  title     = {Mikrobiologische Biomethan-Erzeugung mit Wasserstoff aus der thermischen Vergasung von kohlenstoffhaltigen Einsatzstoffen},
  year      = {2014},
  abstract  = {Die vorliegende Erfindung betrifft ein energieeffizientes, umweltfreundliches und kosteng{\"u}nstiges, vorzugsweise kontinuierliches Verfahren zur Herstellung von Biomethan aus kohlenstoffhaltigen Einsatzstoffen durch die Kombination der thermischen Vergasung mit mikrobiologischer Methan-Erzeugung.},
  language  = {de}
}
@phdthesis{Pettrak2010,
  author    = {Pettrak, J{\"u}rgen},
  title     = {Nutzung nachwachsender Rohstoffe bei der Herstellung thermoplastischer Elastomere aus Folgeprodukten der Olefinmetathese},
  publisher = {Technische Universit{\"a}t M{\"u}nchen},
  address   = {M{\"u}nchen},
  pages     = {137 Seiten},
  year      = {2010},
  abstract  = {Metathese von {\"O}ls{\"a}ure und Derivaten ist ein interessanter Weg f{\"u}r die Synthese bifunktioneller Verbindungen aus nachwachsenden Rohstoffen. Verwendet wurden Ru-Katalysatoren der zweiten Generation, welche eine hohe Toleranz gegen{\"u}ber funktionellen Gruppen und Verunreinigungen aufweisen. Trotz des Einsatzes technischer Edukte waren Umsetzungen mit niedrigen Katalysatormengen (0.001 - 0.01 mol-\%) m{\"o}glich, mit Ausbeuten entsprechend der Literatur. Kreuzmetathesen erm{\"o}glichten variable Kettenl{\"a}ngen und Funktionalit{\"a}ten der Monomere, die Produktgewinnung ist jedoch aufw{\"a}ndig. Selbstmetathese lieferte C18-bifunktionelle Verbindungen, welche einfach durch Destillation oder Kristallisation isoliert werden k{\"o}nnen. Neben der katalystischen Umsetzung wurde auch die Produktgewinnung untersucht und f{\"u}r ausgew{\"a}hlte Produkte auch im gr{\"o}ßeren Maßstab durchgef{\"u}hrt.},
  language  = {de}
}
@article{RieplPettrakFaulstichetal.2010,
  author    = {Riepl, Herbert Matthias and Pettrak, J{\"u}rgen and Faulstich, Martin and Herrmann, Wolfgang Anton},
  title     = {Self metathesis of fatty alcohols and amines to provide monomers for polyester and polyamide products},
  series = {Macromolecular Symposia},
  volume    = {293},
  journal   = {Macromolecular Symposia},
  number    = {1},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-3900 (eISSN)},
  doi       = {10.1002/masy.200900041},
  pages     = {39 -- 42},
  year      = {2010},
  abstract  = {Self metathesis of oleochemicals offers a variety of bifunctional compounds, that can be used as monomer for polymer production. Many precursors are in huge scales available, like oleic acid ester (biodiesel), oleyl alcohol (tensides), oleyl amines (tensides, lubricants). We show several ways to produce and separate and purify C18-α,ω-bifunctional compounds, using Grubbs 2nd Generation catalysts, starting from technical grade educts.},
  language  = {en}
}
@book{Pettrak2014,
  author    = {Pettrak, J{\"u}rgen},
  title     = {Nutzung nachwachsender Rohstoffe bei der Herstellung thermoplastischer Elastomere aus Folgeprodukten der Olefinmetathese},
  publisher = {Attenkofer},
  address   = {Straubing},
  isbn      = {978-3-942742-35-1},
  pages     = {147 Seiten},
  year      = {2014},
  language  = {de}
}
@article{GrosshauserPettrak2023,
  author    = {Großhauser, Christian and Pettrak, J{\"u}rgen},
  title     = {Die Rolle des Wasserstoffs in der Abwasserbehandlung},
  series = {Wasser und Abfall},
  journal   = {Wasser und Abfall},
  number    = {7/8},
  publisher = {Springer Fachmedien},
  address   = {Wiesbaden},
  issn      = {1436-9095},
  doi       = {10.1007/s35152-023-1444-4},
  year      = {2023},
  abstract  = {Die Bereitstellung von nachhaltig erzeugtem Wasserstoff als Energietr{\"a}ger und Rohstoff ist eine wichtige Schl{\"u}sseltechnologie sowohl als Ersatz f{\"u}r fossile Energietr{\"a}ger, aber auch als Produkt im Zusammenhang mit Kreislaufprozessen. In der Abwasserbehandlung bestehen verschiedene M{\"o}glichkeiten Wasserstoff herzustellen. Mehrere Wege, m{\"o}gliche Synergien, aber auch deren Nachteile werden vorgestellt.},
  language  = {de}
}
@misc{DegeringWielandIslametal.2024,
  author    = {Degering, Christian and Wieland, Susanne and Islam, Shohana and Lindner, Claudia and Bongaerts, Johannes and Siegert, Petra and Falkenberg, Fabian},
  title     = {Wasch- und Reinigungsmittel enthaltend Protease (aus Metabacillus indicus)},
  year      = {2024},
  abstract  = {Die Erfindung liegt auf dem Gebiet der Enzymtechnologie. Die Erfindung betrifft Proteasen aus Metabacillus indicus, die insbesondere im Hinblick auf den Einsatz in Wasch- und Reinigungsmitteln verwendet werden k{\"o}nnen, alle hinreichend {\"a}hnlichen Proteasen mit einer entsprechend {\"a}hnlichen Sequenz zu SEQ ID NO:1 und f{\"u}r sie codierende Nukleins{\"a}uren. Die Erfindung betrifft ferner deren Herstellung sowie Verfahren zur Verwendung dieser Proteasen, deren Verwendung als solche sowie diese enthaltende Mittel, insbesondere Wasch- und Reinigungsmittel.},
  language  = {de}
}
@misc{DegeringWielandIslametal.2024,
  author    = {Degering, Christian and Wieland, Susanne and Islam, Shohana and Lindner, Claudia and Siegert, Petra and Falkenberg, Fabian and Bongaerts, Johannes},
  title     = {Wasch- und Reinigungsmittel enthaltend Protease (aus Fictibacillus arsenicus)},
  year      = {2024},
  abstract  = {Die Erfindung liegt auf dem Gebiet der Enzymtechnologie. Die Erfindung betrifft Proteasen aus Fictibacillus arsenicus, die insbesondere im Hinblick auf den Einsatz in Wasch- und Reinigungsmitteln verwendet werden k{\"o}nnen, alle hinreichend {\"a}hnlichen Proteasen mit einer entsprechend {\"a}hnlichen Sequenz zu SEQ ID NO:1 und f{\"u}r sie codierende Nukleins{\"a}uren. Die Erfindung betrifft ferner deren Herstellung sowie Verfahren zur Verwendung dieser Proteasen, deren Verwendung als solche sowie diese enthaltende Mittel, insbesondere Wasch- und Reinigungsmittel.},
  language  = {de}
}
@incollection{Stapenhorst2019,
  author    = {Stapenhorst, Carolin},
  title     = {Werkzeuge und ihre Wirkungsmacht},
  series = {Werkbund Akademiereihe. hefte 19-20 / 2017-2018},
  booktitle = {Werkbund Akademiereihe. hefte 19-20 / 2017-2018},
  editor    = {Deutscher Werkbund NW e.V.,},
  isbn      = {978-3-00-062587-9},
  pages     = {62 -- 74},
  year      = {2019},
  language  = {de}
}
@book{SohnThammHeimannetal.2024,
  author    = {Sohn, Olivia and Thamm, Titus and Heimann, Lara and Andug, Abdullah and Stahl, Johannes and Schultwessel, Tim},
  title     = {Aachener Online-Schriften Wirtschaft und Recht. Band 8. 01/2024},
  editor    = {Kroll-Ludwigs, Kathrin and Bassen-Metz, Yasmine and Bernecker, Andreas and Eggert, Mathias and Fritz, Thomas and Golland, Alexander and H{\"o}hne, Tim and Tran, Duc Hung and Vogt, J{\"u}rgen},
  publisher = {FH Aachen / Fachbereich Wirtschaftswissenschaften},
  address   = {Aachen},
  publisher      = {Fachhochschule Aachen},
  pages     = {380 Seiten},
  year      = {2024},
  abstract  = {1. Auswirkungen des europ{\"a}ischen Data Act: Untersuchung des Verh{\"a}ltnisses zwischen Datenzugang und Datenschutz - Olivia Sohn | Seite 4-58 2. Detecting companies' willingness to invest in their sustainable transformation - relevant factors and their evaluation - Titus Thamm |Seite 59-107 3. Unterschiede in den arbeitsbezogenen Wertvorstellungen der Generation Y und Z? Don't believe the hype - Lara Heimann | Seite 108-199 4. Die virtuelle Mitgliederversammlung beim eingetragenen Verein - ein Modell f{\"u}r die Zukunft? - Abdullah Andug | Seite 200-253 5. Die AGB-Kontrolle von Rechtswahlklauseln in der deutschen und europ{\"a}ischen Kontrollpraxis - Effektiver Verbraucherschutz oder zus{\"a}tzliche Rechtsunsicherheit? - Johannes Stahl | Seite 254-325 6. Datenzugangs-und Nutzungsrechte durch den EU Data Act am Beispiel der Automobilbranche - Tim Schultwessel | Seite 326-380},
  language  = {de}
}
@incollection{Stapenhorst2011,
  author    = {Stapenhorst, Carolin},
  title     = {Identit{\`a} di paesaggi nascosti},
  series = {La casa. Le forme dello stare},
  booktitle = {La casa. Le forme dello stare},
  editor    = {Monestiroli, Antonio and Semerani, Luciano},
  publisher = {Skira},
  address   = {Mailand},
  isbn      = {978-88-572-1006-3},
  pages     = {92 -- 101},
  year      = {2011},
  language  = {it}
}
@techreport{StapenhorstVanDenBerghGoliaschetal.2016,
  author    = {Stapenhorst, Carolin and Van Den Bergh, Wim and Goliasch, Simon and K{\"u}hnle, Christian and L{\"a}ufer, Jonas and Ring, Jana and Schmalt, Nicola},
  title     = {Roman traces for cross-border identification},
  series = {Design Strategies for Transforming Cross-Border Regions},
  journal   = {Design Strategies for Transforming Cross-Border Regions},
  pages     = {5},
  year      = {2016},
  abstract  = {The research group focuses on the characteristics in the land-and cityscapes of the Drielanden-zone, which contribute to generate common identities, as well as on those features that trigger differences and specificities of the adjacent countries that enrich the perception of the zone. In this research, the instruments of cartography and land survey system serve to detect and localize the fragmented appearance of relevant historic elements. These analytic procedures help to develop strategies for infrastructures and processes that gradually initiate local forms of cross-border tourism. The architectural research displays how top-down and bottom-up interventions can be combined in order to guarantee a sustainable use and development of the considered area.},
  language  = {en}
}
@incollection{Stapenhorst2016,
  author    = {Stapenhorst, Carolin},
  title     = {La Land Art come forma di cartografia applicata / Land Art as a Form of Applied Cartography},
  series = {Tracciare piani, disegnare carte / Sketching plans, drawing maps},
  booktitle = {Tracciare piani, disegnare carte / Sketching plans, drawing maps},
  editor    = {Palma, Riccardo and Dutto, Andrea Alberto},
  publisher = {Accademia University Press},
  address   = {Turin},
  isbn      = {978-88-99982-24-9},
  pages     = {195},
  year      = {2016},
  language  = {it}
}
@book{Stapenhorst2016,
  author    = {Stapenhorst, Carolin},
  title     = {Cento Tavole},
  publisher = {RWTH Aachen},
  address   = {Aachen},
  pages     = {50 Seiten},
  year      = {2016},
  language  = {de}
}
@incollection{GuggerStapenhorst2008,
  author    = {Gugger, Harry and Stapenhorst, Carolin},
  title     = {From city to detail: the sphere of the architect},
  series = {Explorations in architecture},
  booktitle = {Explorations in architecture},
  editor    = {Geiser, Reto},
  publisher = {Birkh{\"a}user},
  address   = {Basel},
  isbn      = {978-3-7643-8921-5},
  pages     = {50 -- 53},
  year      = {2008},
  language  = {en}
}
@inproceedings{DiIorioNobileStapenhorst2010,
  author    = {Di Iorio, Marina and Nobile, Maria Luna and Stapenhorst, Carolin},
  title     = {Martinella},
  series = {Edifici alti e paesaggio},
  booktitle = {Edifici alti e paesaggio},
  editor    = {Bovati, Marco and Di Franco, Andrea},
  publisher = {Maggioli},
  address   = {Santarcangelo di Romagna},
  isbn      = {978-88-387-4434-1},
  pages     = {191 -- 202},
  year      = {2010},
  language  = {it}
}
@article{RakeEnningKurthetal.1994,
  author    = {Rake, Heinrich and Enning, Manfred and Kurth, Johannes and Schr{\"o}der, Walter},
  title     = {Automatic uncoupler completes automation at the hump},
  series = {RGI - Railway Gazette International},
  volume    = {150},
  journal   = {RGI - Railway Gazette International},
  number    = {6},
  publisher = {Reed Business},
  address   = {Sutton},
  issn      = {0373-5346},
  pages     = {371 -- 374},
  year      = {1994},
  language  = {en}
}