@article{WerfelGuenthnerHapfelmeieretal.2022,
  author    = {Werfel, Stanislas and G{\"u}nthner, Roman and Hapfelmeier, Alexander and Hanssen, Henner and Kotliar, Konstantin and Heemann, Uwe and Schmaderer, Christoph},
  title     = {Identification of cardiovascular high-risk groups from dynamic retinal vessel signals using untargeted machine learning},
  series = {Cardiovascular Research},
  volume    = {118},
  journal   = {Cardiovascular Research},
  number    = {2},
  editor    = {Guzik, Tomasz J.},
  publisher = {Oxford University Press},
  address   = {Oxford},
  issn      = {0008-6363},
  doi       = {10.1093/cvr/cvab040},
  pages     = {612 -- 621},
  year      = {2022},
  abstract  = {Dynamic retinal vessel analysis (DVA) provides a non-invasive way to assess microvascular function in patients and potentially to improve predictions of individual cardiovascular (CV) risk. The aim of our study was to use untargeted machine learning on DVA in order to improve CV mortality prediction and identify corresponding response alterations.},
  language  = {en}
}
@article{HeinEubanksLingametal.2022,
  author    = {Hein, Andreas M. and Eubanks, T. Marshall and Lingam, Manasvi and Hibberd, Adam and Fries, Dan and Schneider, Jean and Kervella, Pierre and Kennedy, Robert and Perakis, Nikolaos and Dachwald, Bernd},
  title     = {Interstellar now! Missions to explore nearby interstellar objects},
  series = {Advances in Space Research},
  volume    = {69},
  journal   = {Advances in Space Research},
  number    = {1},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0273-1177},
  doi       = {10.1016/j.asr.2021.06.052},
  pages     = {402 -- 414},
  year      = {2022},
  abstract  = {The recently discovered first hyperbolic objects passing through the Solar System, 1I/'Oumuamua and 2I/Borisov, have raised the question about near term missions to Interstellar Objects. In situ spacecraft exploration of these objects will allow the direct determination of both their structure and their chemical and isotopic composition, enabling an entirely new way of studying small bodies from outside our solar system. In this paper, we map various Interstellar Object classes to mission types, demonstrating that missions to a range of Interstellar Object classes are feasible, using existing or near-term technology. We describe flyby, rendezvous and sample return missions to interstellar objects, showing various ways to explore these bodies characterizing their surface, dynamics, structure and composition. Their direct exploration will constrain their formation and history, situating them within the dynamical and chemical evolution of the Galaxy. These mission types also provide the opportunity to explore solar system bodies and perform measurements in the far outer solar system.},
  language  = {en}
}
@article{MalinowskiFournierHorbachetal.2022,
  author    = {Malinowski, Daniel and Fournier, Yvan and Horbach, Andreas and Frick, Michael and Magliani, Mirko and Kalverkamp, Sebastian and Hildinger, Martin and Spillner, Jan and Behbahani, Mehdi and Hima, Flutura},
  title     = {Computational fluid dynamics analysis of endoluminal aortic perfusion},
  series = {Perfusion},
  volume    = {0},
  journal   = {Perfusion},
  number    = {0},
  publisher = {Sage},
  address   = {London},
  issn      = {1477-111X},
  doi       = {10.1177/02676591221099809},
  pages     = {1 -- 8},
  year      = {2022},
  abstract  = {Introduction: In peripheral percutaneous (VA) extracorporeal membrane oxygenation (ECMO) procedures the femoral arteries perfusion route has inherent disadvantages regarding poor upper body perfusion due to watershed. With the advent of new long flexible cannulas an advancement of the tip up to the ascending aorta has become feasible. To investigate the impact of such long endoluminal cannulas on upper body perfusion, a Computational Fluid Dynamics (CFD) study was performed considering different support levels and three cannula positions. Methods: An idealized literature-based- and a real patient proximal aortic geometry including an endoluminal cannula were constructed. The blood flow was considered continuous. Oxygen saturation was set to 80\% for the blood coming from the heart and to 100\% for the blood leaving the cannula. 50\% and 90\% venoarterial support levels from the total blood flow rate of 6 l/min were investigated for three different positions of the cannula in the aortic arch. Results: For both geometries, the placement of the cannula in the ascending aorta led to a superior oxygenation of all aortic blood vessels except for the left coronary artery. Cannula placements at the aortic arch and descending aorta could support supra-aortic arteries, but not the coronary arteries. All positions were able to support all branches with saturated blood at 90\% flow volume. Conclusions: In accordance with clinical observations CFD analysis reveals, that retrograde advancement of a long endoluminal cannula can considerably improve the oxygenation of the upper body and lead to oxygen saturation distributions similar to those of a central cannulation.},
  language  = {en}
}
@article{LenzKahmannBehbahanietal.2022,
  author    = {Lenz, Maximilian and Kahmann, Stephanie Lucina and Behbahani, Mehdi and Pennig, Lenhard and Hackl, Michael and Leschinger, Tim and M{\"u}ller, Lars Peter and Wegmann, Kilian},
  title     = {Influence of rotator cuff preload on fracture configuration in proximal humerus fractures: a proof of concept for fracture simulation},
  series = {Archives of Orthopaedic and Trauma Surgery},
  journal   = {Archives of Orthopaedic and Trauma Surgery},
  publisher = {Springer},
  address   = {Berlin, Heidelberg},
  issn      = {1434-3916},
  doi       = {10.1007/s00402-022-04471-9},
  year      = {2022},
  abstract  = {Introduction In regard of surgical training, the reproducible simulation of life-like proximal humerus fractures in human cadaveric specimens is desirable. The aim of the present study was to develop a technique that allows simulation of realistic proximal humerus fractures and to analyse the influence of rotator cuff preload on the generated lesions in regards of fracture configuration. Materials and methods Ten cadaveric specimens (6 left, 4 right) were fractured using a custom-made drop-test bench, in two groups. Five specimens were fractured without rotator cuff preload, while the other five were fractured with the tendons of the rotator cuff preloaded with 2 kg each. The humeral shaft and the shortened scapula were potted. The humerus was positioned at 90° of abduction and 10° of internal rotation to simulate a fall on the elevated arm. In two specimens of each group, the emergence of the fractures was documented with high-speed video imaging. Pre-fracture radiographs were taken to evaluate the deltoid-tuberosity index as a measure of bone density. Post-fracture X-rays and CT scans were performed to define the exact fracture configurations. Neer's classification was used to analyse the fractures. Results In all ten cadaveric specimens life-like proximal humerus fractures were achieved. Two III-part and three IV-part fractures resulted in each group. The preloading of the rotator cuff muscles had no further influence on the fracture configuration. High-speed videos of the fracture simulation revealed identical fracture mechanisms for both groups. We observed a two-step fracture mechanism, with initial impaction of the head segment against the glenoid followed by fracturing of the head and the tuberosities and then with further impaction of the shaft against the acromion, which lead to separation of the tuberosities. Conclusion A high energetic axial impulse can reliably induce realistic proximal humerus fractures in cadaveric specimens. The preload of the rotator cuff muscles had no influence on initial fracture configuration. Therefore, fracture simulation in the proximal humerus is less elaborate. Using the presented technique, pre-fractured specimens are available for real-life surgical education.},
  language  = {en}
}
@article{ChloeMalyaranCraveiroetal.2022,
  author    = {Chlo{\´e}, Radermacher and Malyaran, Hanna and Craveiro, Rogerio Bastos and Peglow, Sarah and Behbahani, Mehdi and Pufe, Thomas and Wolf, Michael and Neuss, Sabine},
  title     = {Mechanical loading on cementoblasts: a mini review},
  series = {Osteologie},
  volume    = {31},
  journal   = {Osteologie},
  number    = {2},
  publisher = {Thieme},
  address   = {Stuttgart},
  issn      = {1019-1291},
  doi       = {10.1055/a-1826-0777},
  pages     = {111 -- 118},
  year      = {2022},
  abstract  = {Orthodontic treatments are concomitant with mechanical forces and thereby cause teeth movements. The applied forces are transmitted to the tooth root and the periodontal ligaments which is compressed on one side and tensed up on the other side. Indeed, strong forces can lead to tooth root resorption and the crown-to-tooth ratio is reduced with the potential for significant clinical impact. The cementum, which covers the tooth root, is a thin mineralized tissue of the periodontium that connects the periodontal ligament with the tooth and is build up by cementoblasts. The impact of tension and compression on these cells is investigated in several in vivo and in vitro studies demonstrating differences in protein expression and signaling pathways. In summary, osteogenic marker changes indicate that cyclic tensile forces support whereas static tension inhibits cementogenesis. Furthermore, cementogenesis experiences the same protein expression changes in static conditions as static tension, but cyclic compression leads to the exact opposite of cyclic tension. Consistent with marker expression changes, the singaling pathways of Wnt/ß-catenin and RANKL/OPG show that tissue compression leads to cementum degradation and tension forces to cementogenesis. However, the cementum, and in particular its cementoblasts, remain a research area which should be explored in more detail to understand the underlying mechanism of bone resorption and remodeling after orthodontic treatments.},
  language  = {en}
}
@masterthesis{Kaspor2022,
  type      = {Bachelor Thesis},
  author    = {Kaspor, Alexej},
  title     = {Kritik der digitalen Rationalisierung},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {135 Seiten},
  year      = {2022},
  abstract  = {Digitalisierung macht's m{\"o}glich: mittlerweile beziehen sich Designer:innen in ihrer Konzeptentwicklung immer h{\"a}ufiger auf Referenzdesigns. Sie picken sich die Eigenschaften aus ihnen heraus, von denen sie sich die gr{\"o}ßte Marktf{\"a}higkeit versprechen, und basteln sie zu einem neuen Produkt zusammen. Voil{\`a}. Doch wie unkonventionell kann Design noch sein? Wie viel Luft bleibt der Kreativit{\"a}t unter dem immer enger geschn{\"u}rten Korsett der Marktf{\"a}higkeit? Alexej Kaspor er{\"o}ffnet die Diskussion mit einem provokanten Projekt, das einen kritischen Blick in die Zukunft des Industriedesigns wirft. Dazu fasst er g{\"a}ngige Designprogramme in einer Software zusammen und verbindet sie mit einer k{\"u}nstlichen Intelligenz, die die aktuelle Entwicklung digital rationalisieren und auf die Spitze treiben soll. Diese f{\"u}hrt Meta-Analysen {\"u}ber das Nutzungsverhalten durch und pr{\"u}ft damit Frameworks von Referenzdesigns auf ihre Vermarktbarkeit. Aus diesen entwickelt sie dann Gestaltungsvorschl{\"a}ge, ohne beim Seiltanz zwischen Trendh{\"o}rigkeit und Scheinindividualismus aus dem Gleichgewicht zu kommen. Innerhalb von Sekunden werden den Designer:innen perfekte Vorschl{\"a}ge {\"u}bers Metaverse simuliert. Auf dem Silbertablett serviert, {\"u}bersichtlich und gef{\"a}hrlich einfach. Bereit, kombiniert und in Produktion gebracht zu werden. Auch mit dem Tracking der KI kann niemand mithalten: um immer am Puls der Zeit zu bleiben, benachrichtigt sie die Designer:innen in Echtzeit {\"u}ber die neuesten Innovationen und Trends. Ressourcenraubendes Herumprobieren in CAD-Programmen geh{\"o}rt also der Vergangenheit an. Das Programm schafft Abhilfe, und verspricht dabei auch noch die h{\"o}chste Effizienz, konkret: garantiertes Kapital. Schlagende Argumente, die die Schw{\"a}chen der Konsumgesellschaft und Kommerzialisierung gezielt ausgenutzen. Es entsteht die perfekte Marketingmaßnahme, ein genialer Treiber f{\"u}r den Turbokapitalismus. Kram, den niemand braucht und zynische Statussymbole inklusive. Der Stolz der geltungsbed{\"u}rftigen Designer:innen wird dabei selbstverst{\"a}ndlich nicht untergraben. Sie sollen mitziehen. Mit zahlreichen Notches wird der Erfolg und die Konkurrenzf{\"a}higkeit des Produkts prognostiziert und ihnen Honig ums Maul geschmiert. Die beklemmende Vorahnung wird sich best{\"a}tigen. Schritt f{\"u}r Schritt enteignet die KI den Designer:innen ihre Kreativit{\"a}t, bis sie nicht mehr sind als die Kurator:innen berechenbarer Produktkonzepte. Der Sp{\"a}tkapitalismus hat sie in der Mangel. Versprochen: diese Arbeit l{\"a}sst niemanden kalt.},
  language  = {de}
}
@masterthesis{NiggeMans2022,
  type      = {Bachelor Thesis},
  author    = {Nigge-Mans, Leonard},
  title     = {Entwicklung einer Arbeitsplatzleuchte},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {74 Seiten},
  year      = {2022},
  abstract  = {F{\"u}r manche mag es banal wirken, doch f{\"u}r Gestalter:innen ist sie unverzichtbar: eine wirklich gute Leuchte f{\"u}r den Arbeitsplatz. Sie hat n{\"a}mlich einen enormen Einfluss auf die Konzentration und den Komfort. Zudem erm{\"o}glicht gutes Licht erst ein sauberes und farbechtes Ergebnis. Daf{\"u}r wurde in diesem Projekt die perfekte Leuchte entwickelt. Sie leuchtet die Arbeitsfl{\"a}che ideal aus und unterst{\"u}tzt das Lesen, Schreiben oder die Arbeit mit technischen Ger{\"a}ten. Durch f{\"u}nf Drehpunkte ist die Leuchte in alle Richtungen zu bewegen und l{\"a}sst sich somit individuell auf ihre Aufgaben anpassen. Außerdem wurde Wert daraufgelegt, bestehende Normen und Vorschiften einzuhalten, um den Arbeit- und Gesundheitsschutz zu gew{\"a}hrleisten. Feierabend? Durch die Dim-Funktion wird die Arbeitsleuchte zu einer gem{\"u}tlichen Lichtquelle. Unter anderem durch die unsichtbare Stromf{\"u}hrung {\"u}berzeugt die Lampe mit ihrer minimalistischen Designsprache und l{\"a}sst sich in unterschiedlichste R{\"a}ume integrieren.},
  language  = {de}
}
@masterthesis{Lesmeister2022,
  type      = {Bachelor Thesis},
  author    = {Lesmeister, David},
  title     = {VIUR : urbanes Lagerfeuer},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {131 Seiten},
  year      = {2022},
  abstract  = {Es kann ganze Lebensr{\"a}ume ausl{\"o}schen, und doch w{\"a}re unsere Welt nicht die gleiche ohne Feuer. Feuer spielt eine wichtige Rolle in der menschlichen Evolution und diente unseren Vorfahren zum Schutz vor wilden Tieren, Kochen und zum W{\"a}rmen. Auch Gespr{\"a}che am Lagerfeuer sollen einen erheblichen Einfluss auf die soziale und kulturelle Evolution des Menschen gehabt haben. Kein Wunder also, dass die Menschen bis heute mit Feuer ein Gef{\"u}hl von Gemeinschaft und Geborgenheit verbinden. Genau diese Wirkung greift „VIUR" auf und macht Feuer alltagstauglich f{\"u}r eine Welt, die von Urbanisierung und Digitalisierung gepr{\"a}gt ist. Entstanden ist ein Hybrid aus einem Tischfeuer und einem Grill. Somit entsteht sowohl das sinnliche Erlebnis einer Feuerstelle als auch die M{\"o}glichkeit, kleine Speisen zuzubereiten. Die smarte Konstruktion und ein Sicherheitsbrennstoff, mit dem sich kaum Rauch entwickeln kann, erm{\"o}glicht die Nutzung im kleinen Garten, aber eben auch auf einem Stadtbalkon. So kann das Lagerfeuer wieder seinen Zauber entfalten.},
  language  = {de}
}
@inproceedings{EggertChwallekWollf2022,
  author    = {Eggert, Mathias and Chwallek, Constanze and Wollf, Frederik},
  title     = {The role of environmental factors for the success of digital start-ups},
  series = {Thirtieth European Conference on Information Systems (ECIS 2022)},
  booktitle = {Thirtieth European Conference on Information Systems (ECIS 2022)},
  pages     = {1 -- 16},
  year      = {2022},
  abstract  = {Digital start-ups are perceived as an engine for innovation and job promotor. While success factors for non-IT start-ups have already been extensively researched, this study sheds light on digital entrepreneurs, whose business model relies primarily on services based on digital technologies. Applying the Grounded Theory method, we identify relevant environmental success factors for digital entrepreneurs. The study's research contribution is threefold. First, we provide 16 relevant and less relevant environmental success factors, which enables a comparison with prior identified factors. We found out that several prior environmental success factors, such as accessibility to transportation or the availability of land and facilities are less relevant for a digital entrepreneur. Second, we derive and discuss hypotheses for the influence of these factors on digital start-up success. Third, we present a theoretical model that lays the foundation for explaining the environmental influence on digital entrepreneurship success.},
  language  = {de}
}
@incollection{Timme2022,
  author    = {Timme, Michael},
  title     = {Wettbewerbsregeln (\S\S 24-27)},
  series = {M{\"u}nchener Kommentar zum europ{\"a}ischen und deutschen Wettbewerbsrecht : Kartellrecht, Beihilfenrecht, Vergaberecht / hrsg von Franz J{\"u}rgen S{\"a}cker / Band 2: Deutsches Wettbewerbsrecht Gesetz gegen Wettbewerbsbeschr{\"a}nkungen (GWB), \S\S 1-96, 185, 186},
  booktitle = {M{\"u}nchener Kommentar zum europ{\"a}ischen und deutschen Wettbewerbsrecht : Kartellrecht, Beihilfenrecht, Vergaberecht / hrsg von Franz J{\"u}rgen S{\"a}cker / Band 2: Deutsches Wettbewerbsrecht Gesetz gegen Wettbewerbsbeschr{\"a}nkungen (GWB), \S\S 1-96, 185, 186},
  publisher = {Beck},
  address   = {M{\"u}nchen},
  isbn      = {978-3-406-75876-8},
  pages     = {589 -- 608},
  year      = {2022},
  language  = {de}
}