@article{HacklNacovKammerlohretal.2021,
  author    = {Hackl, Michael and Nacov, Julia and Kammerlohr, Sandra and Staat, Manfred and Buess, Eduard and Leschinger, Tim and M{\"u}ller, Lars P. and Wegmann, Kilian},
  title     = {Intratendinous Strain Variations of the Supraspinatus Tendon Depending on Repair Technique: A Biomechanical Analysis Regarding the Cause of Medial Cuff Failure},
  series = {The American Journal of Sports Medicine},
  volume    = {49},
  journal   = {The American Journal of Sports Medicine},
  number    = {7},
  publisher = {Sage},
  address   = {London},
  issn      = {1552-3365},
  doi       = {10.1177/03635465211006138},
  pages     = {1847 -- 1853},
  year      = {2021},
  language  = {en}
}
@incollection{DiekmannEggert2021,
  author    = {Diekmann, Julian and Eggert, Mathias},
  title     = {Is a Progressive Web App an Alternative for Native App Development?},
  series = {3. Wissenschaftsforum: Digitale Transformation (WiFo21) (Lecture Notes in Informatics ; P-319)},
  booktitle = {3. Wissenschaftsforum: Digitale Transformation (WiFo21) (Lecture Notes in Informatics ; P-319)},
  publisher = {Gesellschaft f{\"u}r Informatik},
  address   = {Darmstadt},
  isbn      = {978-3-88579-713-5},
  pages     = {35 -- 48},
  year      = {2021},
  abstract  = {The existence of several mobile operating systems, such as Android and iOS, is a challenge for developers because the individual platforms are not compatible with each other and require separate app developments. For this reason, cross-platform approaches have become popular but lack in cloning the native behavior of the different operating systems. Out of the plenty cross-platform approaches, the progressive web app (PWA) approach is perceived as promising but needs further investigation. Therefore, the paper at hand aims at investigating whether PWAs are a suitable alternative for native apps by developing a PWA clone of an existing app. Two surveys are conducted in which potential users test and evaluate the PWA prototype with regard to its usability. The survey results indicate that PWAs have great potential, but cannot be treated as a general alternative to native apps. For guiding developers when and how to use PWAs, four design guidelines for the development of PWA-based apps are derived based on the results.},
  language  = {en}
}
@article{BurmistrovaSobolevaMonakhova2021,
  author    = {Burmistrova, Natalia A. and Soboleva, Polina M. and Monakhova, Yulia},
  title     = {Is infrared spectroscopy combined with multivariate analysis a promising tool for heparin authentication?},
  series = {Journal of Pharmaceutical and Biomedical Analysis},
  volume    = {194},
  journal   = {Journal of Pharmaceutical and Biomedical Analysis},
  number    = {Article number: 113811},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {0731-7085},
  doi       = {10.1016/j.jpba.2020.113811},
  year      = {2021},
  abstract  = {The investigation of the possibility to determine various characteristics of powder heparin (n = 115) was carried out with infrared spectroscopy. The evaluation of heparin samples included several parameters such as purity grade, distributing company, animal source as well as heparin species (i.e. Na-heparin, Ca-heparin, and heparinoids). Multivariate analysis using principal component analysis (PCA), soft independent modelling of class analogy (SIMCA), and partial least squares - discriminant analysis (PLS-DA) were applied for the modelling of spectral data. Different pre-processing methods were applied to IR spectral data; multiplicative scatter correction (MSC) was chosen as the most relevant. Obtained results were confirmed by nuclear magnetic resonance (NMR) spectroscopy. Good predictive ability of this approach demonstrates the potential of IR spectroscopy and chemometrics for screening of heparin quality. This approach, however, is designed as a screening tool and is not considered as a replacement for either of the methods required by USP and FDA.},
  language  = {en}
}
@article{BurgerRumpfDoetal.2021,
  author    = {Burger, Ren{\´e} and Rumpf, Jessica and Do, Xuan Tung and Monakhova, Yulia and Diehl, Bernd W. K. and Rehahn, Matthias and Schulze, Margit},
  title     = {Is NMR combined with multivariate regression applicable for the molecular weight determination of randomly cross-linked polymers such as lignin?},
  series = {ACS Omega},
  volume    = {6},
  journal   = {ACS Omega},
  number    = {44},
  publisher = {ACS Publications},
  address   = {Washington, DC},
  issn      = {2470-1343},
  doi       = {10.1021/acsomega.1c03574},
  pages     = {29516 -- 29524},
  year      = {2021},
  abstract  = {The molecular weight properties of lignins are one of the key elements that need to be analyzed for a successful industrial application of these promising biopolymers. In this study, the use of 1H NMR as well as diffusion-ordered spectroscopy (DOSY NMR), combined with multivariate regression methods, was investigated for the determination of the molecular weight (Mw and Mn) and the polydispersity of organosolv lignins (n = 53, Miscanthus x giganteus, Paulownia tomentosa, and Silphium perfoliatum). The suitability of the models was demonstrated by cross validation (CV) as well as by an independent validation set of samples from different biomass origins (beech wood and wheat straw). CV errors of ca. 7-9 and 14-16\% were achieved for all parameters with the models from the 1H NMR spectra and the DOSY NMR data, respectively. The prediction errors for the validation samples were in a similar range for the partial least squares model from the 1H NMR data and for a multiple linear regression using the DOSY NMR data. The results indicate the usefulness of NMR measurements combined with multivariate regression methods as a potential alternative to more time-consuming methods such as gel permeation chromatography.},
  language  = {en}
}
@misc{Bartsch2021,
  type      = {Master Thesis},
  author    = {Bartsch, Janosch},
  title     = {Kleidung {\"u}ber Kleidung: eine Bekleidungsserie, die {\"u}ber die Bekleidungsindustrie informiert},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {182 Seiten},
  year      = {2021},
  abstract  = {Kleidung ist ein Kommunikationsmedium. Im Projekt wird Bekleidung als Informationstr{\"a}ger genutzt, um {\"u}ber die verschiedenen Abschnitte im Zyklus eines Kleidungsst{\"u}cks sowie die Missst{\"a}nde in der Bekleidungsindustrie zu informieren. Entstanden sind 6 Kleidungsst{\"u}cke, jeweils eins pro Abschnitt im Zyklus, vom Baumwollanbau {\"u}ber Spinnereien, Produktionsfabriken, dem Einzelhandel und Gebrauch bis zur Entsorgung. Die einfach gehaltenen Kleidungsst{\"u}cke besitzen Aufdrucke. {\"U}ber eine Augmented-Reality-App k{\"o}nnen die Kleidungsst{\"u}cke gescannt werden. In Kombination mit der digitalen Ebene werden die Aufdrucke zu Informationsgrafiken. So wird unter anderem {\"u}ber die grausamen Arbeitsumst{\"a}nde in der Produktion informiert oder dar{\"u}ber, dass wir unsere Kleidungsst{\"u}cke durchschnittlich nur 4x anziehen. Immer geht es darum, den Betrachter dazu anzuregen, seine Konsumentscheidungen zu {\"u}berdenken.},
  language  = {de}
}
@article{BlankeRegerDoeringetal.2021,
  author    = {Blanke, Tobias and Reger, Vitali and D{\"o}ring, Bernd and G{\"o}ttsche, Joachim and Kuhnhenne, Markus},
  title     = {Koaxiale Stahlenergiepf{\"a}hle},
  series = {Stahlbau},
  volume    = {90. 2021},
  journal   = {Stahlbau},
  number    = {6},
  publisher = {Wiley},
  address   = {Weinheim},
  pages     = {417 -- 424},
  year      = {2021},
  abstract  = {Ein entscheidender Teil der Energiewende ist die W{\"a}rmewende im Geb{\"a}udesektor. Ein Schl{\"u}sselelement sind hier W{\"a}rmepumpen. Diese ben{\"o}tigen eine W{\"a}rmequelle, der sie Energie entziehen k{\"o}nnen, um sie auf ein h{\"o}heres Temperaturniveau zu transformieren. Diese W{\"a}rmequelle kann bspw. das Erdreich sein, dessen W{\"a}rme durch Erdsonden erschlossen werden kann. In diesem Beitrag werden in Stahlpf{\"a}hle integrierte Koaxialsonden mit dem Stand der Technik von Erdsonden gleichen Durchmessers bez{\"u}glich ihrer thermischen Leistungsmerkmale verglichen. Die Stahlenergiepf{\"a}hle bieten neben der W{\"a}rmegewinnung weitere Vorteile, da sie auch eine statische Funktion {\"u}bernehmen und r{\"u}ckstandsfrei zur{\"u}ckgebaut werden k{\"o}nnen. Es werden analytische und numerische Berechnungen vorgestellt, um die thermischen Potenziale beider Systeme zu vergleichen. Außerdem wird ein Testaufbau gezeigt, bei dem Stahlenergiepf{\"a}hle in zwei verschiedenen L{\"a}ngen mit vorhandenen g{\"a}ngigen Erdsonden verglichen werden k{\"o}nnen. Die Berechnungen zeigen einen deutlichen thermischen Mehrertrag zwischen 26 \% und 148 \% der Stahlenergiepf{\"a}hle gegen{\"u}ber dem Stand der Technik abh{\"a}ngig vom Erdreich. Die Messergebnisse zeigen einen thermischen Mehrertrag von {\"u}ber 100 \%. Es l{\"a}sst sich also signifikante Erdsondenl{\"a}nge einsparen. Dabei ist zu beachten, dass sich damit der thermisch genutzte Bereich des Erdreichs reduziert, wodurch die thermische Regeneration und/oder das Langzeitverhalten des Erdreichs an Bedeutung gewinnt.},
  language  = {de}
}
@masterthesis{Dieter2021,
  type      = {Bachelor Thesis},
  author    = {Dieter, Helen},
  title     = {Koji - Entwicklung eines h{\"o}henverstellbaren Tisches zur Nutzung in Wohn- und Essr{\"a}umen},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {135 Seiten},
  year      = {2021},
  abstract  = {Um den immer komplexer werdenden Anspr{\"u}chen an Wohnraum gerecht zu werden, braucht es M{\"o}bel, die vielseitig und anpassbar sind. Koji ist ein Tisch, dessen Tischplatte unkompliziert in der H{\"o}he verstellt werden und so in diversen Wohnsituationen eingesetzt werden kann. Er kann als Esstisch genauso genutzt werden wie als Beistell- oder Couchtisch. Durch die Mechanik, die die H{\"o}henverstellbarkeit erm{\"o}glicht, bekommt der Tisch einen verspielten, beinahe lebendigen Charakter, der zur Interaktion einl{\"a}dt. Er ist mehr als ein stummer Begleiter des Alltags, sondern vielmehr Inspiration, seine Umgebung aktiv zu gestalten, um sie so f{\"u}r sich optimal einzurichten.},
  language  = {de}
}
@masterthesis{Kiutsukis2021,
  type      = {Bachelor Thesis},
  author    = {Kiutsukis, Maria},
  title     = {KOMU: Entwicklung eines modularen Regalsystems},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {213 Seiten},
  year      = {2021},
  abstract  = {KOMU entstand durch Analysieren der Ver{\"a}nderungen, die mit der Urbanisierung einhergehen - schnell schwindender Wohnraum, h{\"a}ufiges Umziehen und verschmolzene Raumnutzung. KOMU ist ein modulares Regalsystem, das erm{\"o}glicht, problemlos aus denselben Bestandteilen immer wieder verschiedene Wohn- und Raumsituationen zu schaffen. Das System ist komplett werkzeugfrei durch simples Ineinanderstecken aufzubauen. Weitere Add-Ons k{\"o}nnen {\"u}ber das gleiche Stecksystem in das Regal integriert werden, damit es perfekt an die Bed{\"u}rfnisse des Kunden anpasst werden kann. Durch klare Linien und eine cleane Designsprache f{\"u}gt sich KOMU nahtlos in seine Umgebung ein und hilft, eine f{\"u}r den Kunden ideale Umgebung zu schaffen. Ein Regal, das mitw{\"a}chst - vielf{\"a}ltig und individuell.},
  language  = {de}
}
@masterthesis{Sonntag2021,
  type      = {Bachelor Thesis},
  author    = {Sonntag, Jana},
  title     = {Konzeption und Entwicklung einer Corporate Identity und einer Tourismuskampagne f{\"u}r das Siegerland},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {57 Seiten},
  year      = {2021},
  abstract  = {Im Rahmen meiner Bachelorarbeit werden ich mich mit der Konzeption und Entwicklung einer Corporate Identity f{\"u}r das Siegerland besch{\"a}ftigen. Weiterhin m{\"o}chte ich eine Tourismuskampagne f{\"u}r diese Region gestalten.},
  language  = {de}
}
@inproceedings{AdenackerGerhardsOttenetal.2021,
  author    = {Adenacker, J. and Gerhards, Benjamin and Otten, Christian and Schleser, Markus},
  title     = {Laserstrahlschweißen von Aluminium-Kupfer-Werkstoffkombinationen f{\"u}r die Elektromobilit{\"a}t},
  series = {DVS CONGRESS 2021},
  booktitle = {DVS CONGRESS 2021},
  publisher = {DVS Media GmbH},
  address   = {D{\"u}sseldorf},
  isbn      = {978-3-96144-146-4},
  pages     = {31 -- 38},
  year      = {2021},
  language  = {de}
}
@techreport{GoellBraunsteinAlbracht2021,
  author    = {G{\"o}ll, Fabian and Braunstein, Bj{\"o}rn and Albracht, Kirsten},
  title     = {Lernende roboterassistierte Systeme f{\"u}r das neuromuskul{\"a}re Training - RoSylerNT; Teilvorhaben: Entwicklung eines neuromuskuloskelettalen Modells als Basis f{\"u}r die Interaktionsf{\"a}higkeiten autonomer Assistenzsysteme},
  publisher = {Deutsche Sporthochschule K{\"o}ln},
  address   = {K{\"o}ln},
  doi       = {10.2314/KXP:1855318741},
  pages     = {14 Seiten},
  year      = {2021},
  language  = {de}
}
@masterthesis{Schrey2021,
  type      = {Bachelor Thesis},
  author    = {Schrey, Leander},
  title     = {Less Waste Shelf: Ein M{\"o}bel zur Reduzierung der h{\"a}uslich anfallenden Lebensmittelabf{\"a}lle},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {177 Seiten},
  year      = {2021},
  abstract  = {Mit dem Projekt wird sich dem Problem der weltweiten Lebensmittelverschwendung angenommen und versucht Abf{\"a}lle in Privathaushalten prim{\"a}r industrialisierter Staaten zu reduzieren. Mit j{\"a}hrlich 1,3 Milliarden Tonnen landet circa ein Drittel aller weltweit produzierten Lebensmittel im M{\"u}ll. Einen Großteil dieser Abf{\"a}lle ist vermeidbar, besonders dort, wo man im {\"U}berfluss lebt. Das konzipierte M{\"o}belst{\"u}ck soll die Lagerungsm{\"o}glichkeiten des Nutzers optimieren und somit f{\"u}r die Wertsch{\"a}tzung von Lebensmitteln sensibilisieren. F{\"u}r das M{\"o}belst{\"u}ck werden ausschließlich nat{\"u}rliche Materialien verwendet, welche in ihrer Charakteristik optimal zum Funktionsumfang passen, der f{\"u}r die Lagerung ben{\"o}tigt wird. Das Material Terracotta erm{\"o}glicht es, mittels Verdunstungsk{\"u}hlung stromlos Gem{\"u}se kalt zu halten. Antibakterielles Holz t{\"o}tet sch{\"a}dliche Bakterien ab. Die Konstruktion erm{\"o}glicht somit eine fachgerechte Lebensmittelagerung und erm{\"o}glicht sowohl sehr flexible Nutzung, wie auch leichte Reparatur.},
  language  = {de}
}
@masterthesis{Ernst2021,
  type      = {Bachelor Thesis},
  author    = {Ernst, Loredana},
  title     = {Let´s change fashion!: Eine Image-Kampagne der Fair Wear Foundation f{\"u}r faire und nachhaltige Mode.},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {61 Seiten},
  year      = {2021},
  abstract  = {Fast Fashion-Ketten beherrschen die Modewelt. Doch einige Unternehmen, Siegel und Stiftungen versuchen die Textilindustrie neu umzugestalten. Um die Modeindustrie nachhaltig zu ver{\"a}ndern, m{\"u}ssen allerdings auch den Kunden die schlechten Arbeitsbedingungen und die negativen Einfl{\"u}sse der Textilbranche auf die Umwelt bewusst werden. Das konkrete Ziel der erstellten Kampagne ist es, modebewusste Menschen davon zu {\"u}berzeugen Fast Fashion hinter sich zu lassen. Es soll also ein Umdenken bei den Konsumenten stattfinden. Die Fair Wear Foundation und ihre Mitglieder vertreten die Vision, dass Mode auch fair und nachhaltig sein kann. Genau diese Vision soll mit der Kampagne vermittelt und an die Konsumenten weitergetragen werden.},
  language  = {de}
}
@incollection{CroonCzarnecki2021,
  author    = {Croon, Philipp and Czarnecki, Christian},
  title     = {Liability for loss or damages caused by RPA},
  series = {Robotic process automation : Management, technology, applications},
  booktitle = {Robotic process automation : Management, technology, applications},
  editor    = {Czarnecki, Christian and Fettke, Peter},
  publisher = {De Gruyter},
  address   = {Oldenbourg},
  isbn      = {9783110676778},
  doi       = {10.1515/9783110676693-202},
  pages     = {135 -- 151},
  year      = {2021},
  abstract  = {Intelligent autonomous software robots replacing human activities and performing administrative processes are reality in today's corporate world. This includes, for example, decisions about invoice payments, identification of customers for a marketing campaign, and answering customer complaints. What happens if such a software robot causes a damage? Due to the complete absence of human activities, the question is not trivial. It could even happen that no one is liable for a damage towards a third party, which could create an uncalculatable legal risk for business partners. Furthermore, the implementation and operation of those software robots involves various stakeholders, which result in the unsolvable endeavor of identifying the originator of a damage. Overall it is advisable to all involved parties to carefully consider the legal situation. This chapter discusses the liability of software robots from an interdisciplinary perspective. Based on different technical scenarios the legal aspects of liability are discussed.},
  language  = {en}
}
@article{WeldenJablonskiWegeetal.2021,
  author    = {Welden, Rene and Jablonski, Melanie and Wege, Christina and Keusgen, Michael and Wagner, Patrick Hermann and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Light-Addressable Actuator-Sensor Platform for Monitoring and Manipulation of pH Gradients in Microfluidics: A Case Study with the Enzyme Penicillinase},
  series = {Biosensors},
  volume    = {11},
  journal   = {Biosensors},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2079-6374},
  doi       = {10.3390/bios11060171},
  pages     = {Artikel 171},
  year      = {2021},
  abstract  = {The feasibility of light-addressed detection and manipulation of pH gradients inside an electrochemical microfluidic cell was studied. Local pH changes, induced by a light-addressable electrode (LAE), were detected using a light-addressable potentiometric sensor (LAPS) with different measurement modes representing an actuator-sensor system. Biosensor functionality was examined depending on locally induced pH gradients with the help of the model enzyme penicillinase, which had been immobilized in the microfluidic channel. The surface morphology of the LAE and enzyme-functionalized LAPS was studied by scanning electron microscopy. Furthermore, the penicillin sensitivity of the LAPS inside the microfluidic channel was determined with regard to the analyte's pH influence on the enzymatic reaction rate. In a final experiment, the LAE-controlled pH inhibition of the enzyme activity was monitored by the LAPS.},
  language  = {en}
}
@article{YoshinobuSchoening2021,
  author    = {Yoshinobu, Tatsuo and Sch{\"o}ning, Michael Josef},
  title     = {Light-addressable potentiometric sensors (LAPS) for cell monitoring and biosensing},
  series = {Current Opinion in Electrochemistry},
  journal   = {Current Opinion in Electrochemistry},
  number    = {In Press, Journal Pre-proof},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2451-9103},
  doi       = {10.1016/j.coelec.2021.100727},
  year      = {2021},
  language  = {en}
}
@article{BergsMonakhovaDiehletal.2021,
  author    = {Bergs, Michel and Monakhova, Yulia and Diehl, Bernd W. and Konow, Christopher and V{\"o}lkering, Georg and Pude, Ralf and Schulze, Margit},
  title     = {Lignins isolated via catalyst-free organosolv pulping from Miscanthus x giganteus, M. sinensis, M. robustus and M. nagara: a comparative study},
  series = {Molecules},
  volume    = {26},
  journal   = {Molecules},
  number    = {4},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1420-3049},
  doi       = {10.3390/molecules26040842},
  year      = {2021},
  abstract  = {As a low-input crop, Miscanthus offers numerous advantages that, in addition to agricultural applications, permits its exploitation for energy, fuel, and material production. Depending on the Miscanthus genotype, season, and harvest time as well as plant component (leaf versus stem), correlations between structure and properties of the corresponding isolated lignins differ. Here, a comparative study is presented between lignins isolated from M. x giganteus, M. sinensis, M. robustus and M. nagara using a catalyst-free organosolv pulping process. The lignins from different plant constituents are also compared regarding their similarities and differences regarding monolignol ratio and important linkages. Results showed that the plant genotype has the weakest influence on monolignol content and interunit linkages. In contrast, structural differences are more significant among lignins of different harvest time and/or season. Analyses were performed using fast and simple methods such as nuclear magnetic resonance (NMR) spectroscopy. Data was assigned to four different linkages (A: β-O-4 linkage, B: phenylcoumaran, C: resinol, D: β-unsaturated ester). In conclusion, A content is particularly high in leaf-derived lignins at just under 70\% and significantly lower in stem and mixture lignins at around 60\% and almost 65\%. The second most common linkage pattern is D in all isolated lignins, the proportion of which is also strongly dependent on the crop portion. Both stem and mixture lignins, have a relatively high share of approximately 20\% or more (maximum is M. sinensis Sin2 with over 30\%). In the leaf-derived lignins, the proportions are significantly lower on average. Stem samples should be chosen if the highest possible lignin content is desired, specifically from the M. x giganteus genotype, which revealed lignin contents up to 27\%. Due to the better frost resistance and higher stem stability, M. nagara offers some advantages compared to M. x giganteus. Miscanthus crops are shown to be very attractive lignocellulose feedstock (LCF) for second generation biorefineries and lignin generation in Europe.},
  language  = {en}
}
@article{AkimbekovDigelAbdievaetal.2021,
  author    = {Akimbekov, Nuraly and Digel, Ilya and Abdieva, Gulzhamal and Ualieva, Perizat and Tastambek, Kuanysh},
  title     = {Lignite biosolubilization and bioconversion by Bacillus sp.: the collation of analytical data},
  series = {Biofuels},
  volume    = {12},
  journal   = {Biofuels},
  number    = {3},
  publisher = {Taylor \& Francis},
  address   = {London},
  issn      = {1759-7277},
  pages     = {247 -- 258},
  year      = {2021},
  abstract  = {The vast metabolic potential of microbes in brown coal (lignite) processing and utilization can greatly contribute to innovative approaches to sustainable production of high-value products from coal. In this study, the multi-faceted and complex coal biosolubilization process by Bacillus sp. RKB 7 isolate from the Kazakhstan coal-mining soil is reported, and the derived products are characterized. Lignite solubilization tests performed for surface and suspension cultures testify to the formation of numerous soluble lignite-derived substances. Almost 24\% of crude lignite (5\% w/v) was solubilized within 14 days under slightly alkaline conditions (pH 8.2). FTIR analysis revealed various functional groups in the obtained biosolubilization products. Analyses of the lignite-derived humic products by UV-Vis and fluorescence spectrometry as well as elemental analysis yielded compatible results indicating the emerging products had a lower molecular weight and degree of aromaticity. Furthermore, XRD and SEM analyses were used to evaluate the biosolubilization processes from mineralogical and microscopic points of view. The findings not only contribute to a deeper understanding of microbe-mineral interactions in coal environments, but also contribute to knowledge of coal biosolubilization and bioconversion with regard to sustainable production of humic substances. The detailed and comprehensive analyses demonstrate the huge biotechnological potential of Bacillus sp. for agricultural productivity and environmental health.},
  language  = {en}
}
@masterthesis{Bos2021,
  type      = {Bachelor Thesis},
  author    = {Bos, Shania},
  title     = {Living Books: ein Event rund um das Thema Lesen},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {95 Seiten},
  year      = {2021},
  abstract  = {Living Books ist ein in Aachen stationiertes Event der Buchhandlungskette Mayersche, welches Kinder und Jugendliche zum Lesen animieren soll, indem Technik und Unterhaltungsmedien mit dem Buch verbunden werden. Hierzu werden die M{\"o}glichkeiten der virtuellen Realit{\"a}t genutzt sowie einzigartige Marketingstrategien, die sich ebenfalls neuartiger Technik bedienen, um das Interesse und die Neugierde junger Menschen zu wecken. Vor Ort wird man zum ersten Mal mit dem Buch konfrontiert. Bis dahin wirkt das Event schlichtweg wie ein Fantreffen zu Buchverfilmungen. Nacheinander betreten die jungen Besucher mithilfe einer VR-Brille eine Welt, die einem Buch entstammt, um ihnen die Geschichte spielerisch n{\"a}herzubringen. Mithilfe der neuen Welt und einem pl{\"o}tzlichen Ende soll Neugierde f{\"u}r das Buch geweckt werden. Das Interesse f{\"u}r die Geschichte soll am Ende gr{\"o}ßer sein als die Abneigung gegen das Lesen.},
  language  = {de}
}
@masterthesis{Niederschmidt2021,
  type      = {Bachelor Thesis},
  author    = {Niederschmidt, S{\"o}ren},
  title     = {Living product: ein Ansatz, lebendige Organismen mit einem Produkt zu vereinen und nutzbar zu machen},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {57 Seiten},
  year      = {2021},
  abstract  = {Diese Arbeit setzt sich mit der Frage auseinander, in welcher Form sich lebendige Organismen - hier insbesondere Pilze - in die Produktwelt integrieren lassen. In welcher Art und Weise beeinflusst ein Organismus das Produkterlebnis? Im Rahmen dieser Arbeit sind vier verschiedene Produkte entstanden, die die St{\"a}rken des Materials Myzelium demonstrieren. Myzelium bezeichnet das sehr dichte Wurzelnetzwerk eines Pilzes. Dieses lebendige Netzwerk kann dazu genutzt werden, um organische Stoffe miteinander zu verwachsen und somit Formen entstehen zu lassen. Die so entstandenen Produkte sind in eine Konzeptumgebung eingebettet, in der der Verbrauchende die Natur durch naturn{\"a}here Produkte (Form, Material und gewachsene Strukturen) neu erlebt. Gezeigt wird ein Packaging f{\"u}r Einmachgl{\"a}ser, ein Kressebeet, ein Wandregal und ein Teelicht.},
  language  = {de}
}
@masterthesis{Zaunbrecher2021,
  type      = {Bachelor Thesis},
  author    = {Zaunbrecher, Fabienne},
  title     = {Living Spaces - By OASE: Konzeption eines Flagship-Stores mit Wohlf{\"u}hl- und Erlebnis-Spaces},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {175 Seiten},
  year      = {2021},
  abstract  = {Konzeption eines Flagship-Stores mit Wohlf{\"u}hl- und Erlebnis-Spaces Die Bed{\"u}rfnisse von Besuchern und Kunden eines Gesch{\"a}fts haben sich {\"u}ber die letzten Jahre stark ver{\"a}ndert. Sie m{\"o}chten das ihr Kauf zum Erlebnis wird. Auf Basis dieser Erkenntnis wurde im Rahmen dieser Arbeit zusammen mit den Produkten des Weltmarktf{\"u}hrers f{\"u}r Teichtechnik und Aquaristik „OASE - Living Water" ein Storekonzept geschaffen. Dieses verbindet den Verkaufsraum mit unterschiedlichen Erlebniswelten, welche auf die jeweilig ausgestellte Produktkategorie abgestimmt sind. Zus{\"a}tzlich er{\"o}ffnet ein diverser und aufregend gestalteter Gartenbereich der zum Entspannen und Verweilen einl{\"a}dt. Der herausstechende Aspekt des Konzepts ist, dass die Produkte sowohl als reines Produkt, als auch in verbauter Version in Aktion zu sehen sind. Auf diese Art bietet die Marke „OASE - Living Water" ein neues Kauf-Erlebnis an.},
  language  = {de}
}
@article{AkimbekovDigelTastambeketal.2021,
  author    = {Akimbekov, Nuraly S. and Digel, Ilya and Tastambek, Kuanysh T. and Sherelkhan, Dinara K. and Jussupova, Dariya B. and Altynbay, Nazym P.},
  title     = {Low-rank coal as a source of humic substances for soil amendment and fertility management},
  series = {Agriculture},
  volume    = {11},
  journal   = {Agriculture},
  number    = {12},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2077-0472},
  doi       = {10.3390/agriculture11121261},
  pages     = {25 Seiten},
  year      = {2021},
  abstract  = {Humic substances (HS), as important environmental components, are essential to soil health and agricultural sustainability. The usage of low-rank coal (LRC) for energy generation has declined considerably due to the growing popularity of renewable energy sources and gas. However, their potential as soil amendment aimed to maintain soil quality and productivity deserves more recognition. LRC, a highly heterogeneous material in nature, contains large quantities of HS and may effectively help to restore the physicochemical, biological, and ecological functionality of soil. Multiple emerging studies support the view that LRC and its derivatives can positively impact the soil microclimate, nutrient status, and organic matter turnover. Moreover, the phytotoxic effects of some pollutants can be reduced by subsequent LRC application. Broad geographical availability, relatively low cost, and good technical applicability of LRC offer the advantage of easy fulfilling soil amendment and conditioner requirements worldwide. This review analyzes and emphasizes the potential of LRC and its numerous forms/combinations for soil amelioration and crop production. A great benefit would be a systematic investment strategy implicating safe utilization and long-term application of LRC for sustainable agricultural production.},
  language  = {en}
}
@article{KaschSchmidtJahnetal.2021,
  author    = {Kasch, Susanne and Schmidt, Thomas and Jahn, Simon and Eichler, Fabian and Thurn, Laura and Bremen, Sebastian},
  title     = {L{\"o}sungsans{\"a}tze und Verfahrenskonzepte zum Laserstrahlschmelzen von Glas},
  series = {Schweissen und Schneiden},
  volume    = {73},
  journal   = {Schweissen und Schneiden},
  number    = {Heft 1-2},
  publisher = {DVS Verlag},
  address   = {D{\"u}sseldorf},
  isbn      = {0036-7184},
  pages     = {32 -- 39},
  year      = {2021},
  language  = {de}
}
@inproceedings{NikolovskiRekeElsenetal.2021,
  author    = {Nikolovski, Gjorgji and Reke, Michael and Elsen, Ingo and Schiffer, Stefan},
  title     = {Machine learning based 3D object detection for navigation in unstructured environments},
  series = {2021 IEEE Intelligent Vehicles Symposium Workshops (IV Workshops)},
  booktitle = {2021 IEEE Intelligent Vehicles Symposium Workshops (IV Workshops)},
  publisher = {IEEE},
  isbn      = {978-1-6654-7921-9},
  doi       = {10.1109/IVWorkshops54471.2021.9669218},
  pages     = {236 -- 242},
  year      = {2021},
  abstract  = {In this paper we investigate the use of deep neural networks for 3D object detection in uncommon, unstructured environments such as in an open-pit mine. While neural nets are frequently used for object detection in regular autonomous driving applications, more unusual driving scenarios aside street traffic pose additional challenges. For one, the collection of appropriate data sets to train the networks is an issue. For another, testing the performance of trained networks often requires tailored integration with the particular domain as well. While there exist different solutions for these problems in regular autonomous driving, there are only very few approaches that work for special domains just as well. We address both the challenges above in this work. First, we discuss two possible ways of acquiring data for training and evaluation. That is, we evaluate a semi-automated annotation of recorded LIDAR data and we examine synthetic data generation. Using these datasets we train and test different deep neural network for the task of object detection. Second, we propose a possible integration of a ROS2 detector module for an autonomous driving platform. Finally, we present the performance of three state-of-the-art deep neural networks in the domain of 3D object detection on a synthetic dataset and a smaller one containing a characteristic object from an open-pit mine.},
  language  = {en}
}
@incollection{EngelmannShashaSlabu2021,
  author    = {Engelmann, Ulrich M. and Shasha, Carolyn and Slabu, Ioana},
  title     = {Magnetic nanoparticle relaxation in biomedical application: focus on simulating nanoparticle heating},
  series = {Magnetic nanoparticles in human health and medicine},
  booktitle = {Magnetic nanoparticles in human health and medicine},
  publisher = {Wiley-Blackwell},
  address   = {Hoboken, New Jeersey},
  isbn      = {978-1-119-75467-1},
  pages     = {327 -- 354},
  year      = {2021},
  language  = {en}
}
@masterthesis{Hahn2021,
  type      = {Bachelor Thesis},
  author    = {Hahn, Veronika},
  title     = {Masculinity: M{\"a}nnlichkeit im 21. Jahrhundert},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {62 Seiten},
  year      = {2021},
  abstract  = {Was ist „M{\"a}nnlichkeit" und was verstehen junge Erwachsene unter diesem Begriff? Das Ziel des Projektes war 18 bis 30 j{\"a}hrige Jungen und M{\"a}nner des biologisch m{\"a}nnlichen Geschlechts zu befragen, was ihre Definition von M{\"a}nnlichkeit sei. Diese Arbeit hatte die Intention den Befragten einen sicheren Raum zu geben, damit sie ihre ehrlichen Antworten {\"a}ußern und ihre wahren Gesichter zeigen k{\"o}nnen. Die dabei entstandenen Fotografien sollen die Pers{\"o}nlichkeiten und die seelische Verfassung der abgebildeten Personen widerspiegeln. Es handelt sich um eine soziologische Bestandsaufnahme der „M{\"a}nnlichkeiten" der heutigen Jugend und der heranwachsenden Erwachsenen im 21. Jahrhundert.},
  language  = {de}
}
@article{WerkhausenWillwacherAlbracht2021,
  author    = {Werkhausen, Amelie and Willwacher, Steffen and Albracht, Kirsten},
  title     = {Medial gastrocnemius muscle fascicles shorten throughout stance during sprint acceleration},
  series = {Scandinavian Journal of Medicine \& Science in Sports},
  volume    = {31},
  journal   = {Scandinavian Journal of Medicine \& Science in Sports},
  number    = {7},
  publisher = {Wiley-Blackwell},
  address   = {Oxford},
  issn      = {0905-7188 (Druckausgabe)},
  doi       = {10.1111/sms.13956},
  pages     = {1471 -- 1480},
  year      = {2021},
  abstract  = {The compliant nature of distal limb muscle-tendon units is traditionally considered suboptimal in explosive movements when positive joint work is required. However, during accelerative running, ankle joint net mechanical work is positive. Therefore, this study aims to investigate how plantar flexor muscle-tendon behavior is modulated during fast accelerations. Eleven female sprinters performed maximum sprint accelerations from starting blocks, while gastrocnemius muscle fascicle lengths were estimated using ultrasonography. We combined motion analysis and ground reaction force measurements to assess lower limb joint kinematics and kinetics, and to estimate gastrocnemius muscle-tendon unit length during the first two acceleration steps. Outcome variables were resampled to the stance phase and averaged across three to five trials. Relevant scalars were extracted and analyzed using one-sample and two-sample t-tests, and vector trajectories were compared using statistical parametric mapping. We found that an uncoupling of muscle fascicle behavior from muscle-tendon unit behavior is effectively used to produce net positive mechanical work at the joint during maximum sprint acceleration. Muscle fascicles shortened throughout the first and second steps, while shortening occurred earlier during the first step, where negative joint work was lower compared with the second step. Elastic strain energy may be stored during dorsiflexion after touchdown since fascicles did not lengthen at the same time to dissipate energy. Thus, net positive work generation is accommodated by the reuse of elastic strain energy along with positive gastrocnemius fascicle work. Our results show a mechanism of how muscles with high in-series compliance can contribute to net positive joint work.},
  language  = {en}
}
@masterthesis{Thomaschik2021,
  type      = {Bachelor Thesis},
  author    = {Thomaschik, Annika},
  title     = {Medical Design for Kids: Integration der Bed{\"u}rfnisse von Kindern in medizinische Produkte},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {122 Seiten},
  year      = {2021},
  abstract  = {Kinder im Kontext von medizinischen Einrichtungen. Kinder sind keine kleinen Erwachsenen und erfordern einen auf sie angepassten Zugang zu medizinischen Behandlungsabl{\"a}ufen. Das Konzept basiert auf dem Gestaltungsprinzip des „Child Centered Design" mit Befragungen von Experten der P{\"a}diatrie und Forschung sowie mit enger Zusammenarbeit mit Kindern. Entstanden ist ein Produkt welches Skepsis und Angst junger Patienten im Alter von 6 bis 14 Jahren bei station{\"a}ren Aufenthalten in Krankenh{\"a}usern mindert und ihren Heilungsprozess positiv unterst{\"u}tzt. Unter Einbezug von digitalen M{\"o}glichkeiten wie Augmented Reality erkl{\"a}rt „ViU", ein Krankenhaus-Companion in Eulen-Optik, den kleinen Patienten Funktionen und das Wirken verschiedenster medizinischer Ger{\"a}te und Behandlungen. So wird nicht nur der Rate an Traumata durch Krankenhausaufenthalte bei Kindern entgegengewirkt, sondern auch das Krankenhauspersonal im Umgang mit Kindern im Klinikalltag entlastet.},
  language  = {de}
}
@inproceedings{SchulzeBuxlohGross2021,
  author    = {Schulze-Buxloh, Lina and Groß, Rolf Fritz},
  title     = {Miniature urban farming plant: a complex educational "Toy" for engineering students},
  series = {The Future of Education 11th Edition 2021},
  booktitle = {The Future of Education 11th Edition 2021},
  pages     = {4 Seiten},
  year      = {2021},
  abstract  = {Urban farming is an innovative and sustainable way of food production and is becoming more and more important in smart city and quarter concepts. It also enables the production of certain foods in places where they usually dare not produced, such as production of fish or shrimps in large cities far away from the coast. Unfortunately, it is not always possible to show students such concepts and systems in real life as part of courses: visits of such industry plants are sometimes not possible because of distance or are permitted by the operator for hygienic reasons. In order to give the students the opportunity of getting into contact with such an urban farming system and its complex operation, an industrial urban farming plant was set up on a significantly smaller scale. Therefore, all needed technical components like water aeriation, biological and mechanical filtration or water circulation have been replaced either by aquarium components or by self-designed parts also using a 3D-printer. Students from different courses like mechanical engineering, smart building engineering, biology, electrical engineering, automation technology and civil engineering were involved in this project. This "miniature industrial plant" was also able to start operation and has now been running for two years successfully. Due to Corona pandemic, home office and remote online lectures, the automation of this miniature plant should be brought to a higher level in future for providing a good control over the system and water quality remotely. The aim of giving the student a chance to get to know the operation of an urban farming plant was very well achieved and the students had lots of fun in "playing" and learning with it in a realistic way.},
  language  = {en}
}
@masterthesis{Beil2021,
  type      = {Bachelor Thesis},
  author    = {Beil, Franziska},
  title     = {Mobilit{\"a}t im Alter: der Rollator der n{\"a}chsten Generation},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {73 Seiten},
  year      = {2021},
  abstract  = {Da die Gesellschaft in Deutschland immer {\"a}lter wird, steigt auch die Nachfrage nach Gehhilfen wie beispielsweise einem Rollator. Im Alter steigt das Erkrankungsrisiko f{\"u}r Krankheiten, die die Mobilit{\"a}t erschweren k{\"o}nnen. An diesem Punkt setzt der Rollator MORO an und bietet wieder Sicherheit beim Gehen. F{\"u}r den MORO sind Hindernisse wie Bordsteinkanten kein Problem, da er sie mit speziellen R{\"a}dern spielend {\"u}berwinden kann. Zus{\"a}tzlich bietet er ergonomische Handgriffe, die entsprechend der jeweiligen Krankheit angepasst und ausgetauscht werden k{\"o}nnen sowie einen Sitz und eine R{\"u}ckenlehne. Da der MORO aus Carbon hergestellt wird, ist er leicht in der Handhabung und somit wird die Mitnahme im Auto oder Bus und Bahn erleichtert. Durch seine verbesserte Ergonomie, individueller Anpassung und Leichtigkeit kann man wieder selbstst{\"a}ndig durch die Welt gehen.},
  language  = {de}
}
@inproceedings{GrundmannBorellaCeriottietal.2021,
  author    = {Grundmann, Jan Thimo and Borella, Laura and Ceriotti, Matteo and Chand, Suditi and Cordero, Federico and Dachwald, Bernd and Fexer, Sebastian and Grimm, Christian D. and Hendrikse, Jeffrey and Herč{\´i}k, David and Herique, Alain and Hillebrandt, Martin and Ho, Tra-Mi and Kesseler, Lars and Laabs, Martin and Lange, Caroline and Lange, Michael and Lichtenheldt, Roy and McInnes, Colin R. and Moore, Iain and Peloni, Alessandro and Plettenmeier, Dirk and Quantius, Dominik and Seefeldt, Patric and Venditti, Flaviane c. F. and Vergaaij, Merel and Viavattene, Giulia and Virkki, Anne K. and Zander, Martin},
  title     = {More bucks for the bang: new space solutions, impact tourism and one unique science \& engineering opportunity at T-6 months and counting},
  series = {7th IAA Planetary Defense Conference},
  booktitle = {7th IAA Planetary Defense Conference},
  year      = {2021},
  abstract  = {For now, the Planetary Defense Conference Exercise 2021's incoming fictitious(!), asteroid, 2021 PDC, seems headed for impact on October 20th, 2021, exactly 6 months after its discovery. Today (April 26th, 2021), the impact probability is 5\%, in a steep rise from 1 in 2500 upon discovery six days ago. We all know how these things end. Or do we? Unless somebody kicked off another headline-grabbing media scare or wants to keep civil defense very idle very soon, chances are that it will hit (note: this is an exercise!). Taking stock, it is barely 6 months to impact, a steadily rising likelihood that it will actually happen, and a huge uncertainty of possible impact energies: First estimates range from 1.2 MtTNT to 13 GtTNT, and this is not even the worst-worst case: a 700 m diameter massive NiFe asteroid (covered by a thin veneer of Ryugu-black rubble to match size and brightness), would come in at 70 GtTNT. In down to Earth terms, this could be all between smashing fireworks over some remote area of the globe and a 7.5 km crater downtown somewhere. Considering the deliberate and sedate ways of development of interplanetary missions it seems we can only stand and stare until we know well enough where to tell people to pack up all that can be moved at all and save themselves. But then, it could just as well be a smaller bright rock. The best estimate is 120 m diameter from optical observation alone, by 13\% standard albedo. NASA's upcoming DART mission to binary asteroid (65803) Didymos is designed to hit such a small target, its moonlet Dimorphos. The Deep Impact mission's impactor in 2005 successfully guided itself to the brightest spot on comet 9P/Tempel 1, a relatively small feature on the 6 km nucleus. And 'space' has changed: By the end of this decade, one satellite communication network plans to have launched over 11000 satellites at a pace of 60 per launch every other week. This level of series production is comparable in numbers to the most prolific commercial airliners. Launch vehicle production has not simply increased correspondingly - they can be reused, although in a trade for performance. Optical and radio astronomy as well as planetary radar have made great strides in the past decade, and so has the design and production capability for everyday 'high-tech' products. 60 years ago, spaceflight was invented from scratch within two years, and there are recent examples of fast-paced space projects as well as a drive towards 'responsive space'. It seems it is not quite yet time to abandon all hope. We present what could be done and what is too close to call once thinking is shoved out of the box by a clear and present danger, to show where a little more preparedness or routine would come in handy - or become decisive. And if we fail, let's stand and stare safely and well instrumented anywhere on Earth together in the greatest adventure of science.},
  language  = {en}
}
@masterthesis{MeinersSchneider2021,
  type      = {Bachelor Thesis},
  author    = {Meiners, Sonja and Schneider, Sophie},
  title     = {MULO - Multifunktionale Objekte: Eine Serie multifunktionaler Wohnobjekte},
  publisher = {FH Aachen},
  address   = {Aachen},
  pages     = {137 Seiten},
  year      = {2021},
  abstract  = {Mit MULO wurde eine Serie multifunktionaler Objekte f{\"u}r den Wohnbereich entworfen. In Zeiten des {\"U}berangebots und des st{\"a}ndigen Wohnraumwechsels soll der Nutzer dieser Objekte mit einem modernen und schlichten Design unterst{\"u}tzt werden, das zu jedem Anlass passt. Die minimalistische {\"A}sthetik mit hohem Komfort orientiert sich dabei an den Bed{\"u}rfnissen des Endverbrauchers. Als Verwandlungsk{\"u}nstler bereichert MULO jeden Wohnraum. Die gesamte Serie ist unter der Ber{\"u}cksichtigung der schnelllebigen und sich wandelnden Welt entworfen worden. Mit multifunktionalen Objekten ist das Produkt den flexiblen Anforderungen und Bed{\"u}rfnissen des Menschen gewachsen. Die Bereiche Wohnen, Leben, Arbeiten, Schlafen und Entspannen werden durch das Sofa- , das Tisch- und das Keramik-System optimal abgedeckt. Durch die Verwendung von nachhaltigen und recycelbaren Materialien, setzt MULO ein kleines Statement und hinterl{\"a}sst nachhaltig Eindruck.},
  language  = {de}
}
@inproceedings{KloeserKohlKraftetal.2021,
  author    = {Kl{\"o}ser, Lars and Kohl, Philipp and Kraft, Bodo and Z{\"u}ndorf, Albert},
  title     = {Multi-attribute relation extraction (MARE): simplifying the application of relation extraction},
  series = {Proceedings of the 2nd International Conference on Deep Learning Theory and Applications - DeLTA},
  booktitle = {Proceedings of the 2nd International Conference on Deep Learning Theory and Applications - DeLTA},
  isbn      = {978-989-758-526-5},
  doi       = {10.5220/0010559201480156},
  pages     = {148 -- 156},
  year      = {2021},
  abstract  = {Natural language understanding's relation extraction makes innovative and encouraging novel business concepts possible and facilitates new digitilized decision-making processes. Current approaches allow the extraction of relations with a fixed number of entities as attributes. Extracting relations with an arbitrary amount of attributes requires complex systems and costly relation-trigger annotations to assist these systems. We introduce multi-attribute relation extraction (MARE) as an assumption-less problem formulation with two approaches, facilitating an explicit mapping from business use cases to the data annotations. Avoiding elaborated annotation constraints simplifies the application of relation extraction approaches. The evaluation compares our models to current state-of-the-art event extraction and binary relation extraction methods. Our approaches show improvement compared to these on the extraction of general multi-attribute relations.},
  language  = {en}
}
@article{PourshahidiAchtsnichtNambipareecheeetal.2021,
  author    = {Pourshahidi, Ali Mohammad and Achtsnicht, Stefan and Nambipareechee, Mrinal Murali and Offenh{\"a}usser, Andreas and Krause, Hans-Joachim},
  title     = {Multiplex detection of magnetic beads using offset field dependent frequency mixing magnetic detection},
  series = {Sensors},
  volume    = {21},
  journal   = {Sensors},
  number    = {17},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s21175859},
  pages     = {16 Seiten},
  year      = {2021},
  abstract  = {Magnetic immunoassays employing Frequency Mixing Magnetic Detection (FMMD) have recently become increasingly popular for quantitative detection of various analytes. Simultaneous analysis of a sample for two or more targets is desirable in order to reduce the sample amount, save consumables, and save time. We show that different types of magnetic beads can be distinguished according to their frequency mixing response to a two-frequency magnetic excitation at different static magnetic offset fields. We recorded the offset field dependent FMMD response of two different particle types at frequencies ƒ₁ + n⋅ƒ₂, n = 1, 2, 3, 4 with ƒ₁ = 30.8 kHz and ƒ₂ = 63 Hz. Their signals were clearly distinguishable by the locations of the extremes and zeros of their responses. Binary mixtures of the two particle types were prepared with different mixing ratios. The mixture samples were analyzed by determining the best linear combination of the two pure constituents that best resembled the measured signals of the mixtures. Using a quadratic programming algorithm, the mixing ratios could be determined with an accuracy of greater than 14\%. If each particle type is functionalized with a different antibody, multiplex detection of two different analytes becomes feasible.},
  language  = {en}
}
@article{MontiWaldvogelRitzmannetal.2021,
  author    = {Monti, Elena and Waldvogel, Janice and Ritzmann, Ramona and Freyler, Kathrin and Albracht, Kirsten and Helm, Michael and De Cesare, Niccol{\`o} and Pavan, Piero and Reggiani, Carlo and Gollhofer, Albert and Narici, Marco Vincenzo},
  title     = {Muscle in variable gravity: "I do not know where I am, but I know what to do"},
  series = {Frontiers in Physiology},
  volume    = {12},
  journal   = {Frontiers in Physiology},
  publisher = {Frontiers Research Foundation},
  address   = {Lausanne},
  issn      = {1664-042X},
  doi       = {10.3389/fphys.2021.714655},
  pages     = {19 Seiten},
  year      = {2021},
  abstract  = {Performing tasks, such as running and jumping, requires activation of the agonist and antagonist muscles before (motor unit pre-activation) and during movement performance (Santello and Mcdonagh, 1998). A well-timed and regulated muscle activation elicits a stretch-shortening cycle (SSC) response, naturally occurring in bouncing movements (Ishikawa and Komi, 2004; Taube et al., 2012). By definition, the SSC describes the stretching of a pre-activated muscle-tendon complex immediately followed by a muscle shortening in the concentric push-off phase (Komi, 1984). Given the importance of SSC actions for human movement, it is not surprising that many studies investigated the biomechanics of this phenomenon; in particular, drop jumps (DJs) represent a good paradigm to study muscle fascicle and tendon behavior in ballistic movements involving the SSC. Within a DJ, three main phases [pre-activation, braking, and push-off (PO; Komi, 2000)] have been recognized and extensively studied in common and challenging conditions, such as changes in load, falling height, or simulated hypo-gravity (Avela et al., 1994; Arampatzis et al., 2001; Fukashiro et al., 2005; Ishikawa et al., 2005; Sousa et al., 2007; Ritzmann et al., 2016; Helm et al., 2020). These studies show that the timing and amount of triceps-surae muscle-tendon unit pre-activation in DJs are differentially regulated based on the load applied to the muscle, being optimal in normal "Earth" gravity conditions (Avela et al., 1994), but decreased in simulated hypo-gravity, hyper-gravity (Avela et al., 1994; Ritzmann et al., 2016), or unknown conditions (i.e., unknown falling heights; Helm et al., 2020). Some authors indicated that, when falling from heights different from the optimal one [defined as the drop height giving a maximum DJ performance indicated as peak ground reaction force (GRF) or jump high], electromyographic (EMG) activity of the plantar flexors increases from lower than optimal to higher than optimal heights (Ishikawa and Komi, 2004; Sousa et al., 2007). These findings highlight the ability of the central nervous system to regulate the timing and amount of pre-activation according to different jumping conditions, thus regulating muscle fascicle length, tendon and joint stiffness as well as position, in order to safely land on the ground and quickly re-bounce. Similarly, to pre-activation, also in the braking phase, the plantar flexors are differentially regulated. In optimal height (i.e., load) jumping conditions, gastrocnemius medialis (GM) fascicles shorten at early ground contact (possibly due to the intervention of the stretch reflex; Gollhofer et al., 1992) and behave quasi-isometrically in the late braking phase, enabling tendon elongation, and storage of elastic energy (Gollhofer et al., 1992; Fukashiro et al., 2005; Sousa et al., 2007). When increasing the falling height (augmenting the impact GRF), the quasi-isometric behavior of fascicles disappears, and fast fascicle lengthening occurs (Ishikawa et al., 2005; Sousa et al., 2007). In the third and last PO phase, fascicles shorten and the tendon releases the elastic energy previously stored. Bobbert et al. (1987) reported no influence of jumping height on the work done and on the net vertical impulse assessed during PO; this observation suggests that, despite an optimal DJ performance might be achieved only in specific conditions (falling heights, loads), the central nervous system seems to be able to regulate muscle behavior in order to effectively perform the required task also in challenging situations. Although the regulation of triceps-surae muscle-tendon unit in DJs has been extensively investigated, very few studies focused on sarcomeres behavior during the performance of this SSC movement (Kurokawa et al., 2003; Fukashiro et al., 2005, 2006). Sarcomeres represent muscle contractile units and are known to express different amounts of force depending on their length (Gordon et al., 1966; Walker and Schrodt, 1974); thus, understanding the time course of their responses during DJs is fundamental to gain further insights into muscle force-generating capacity. In vivo measurement of sarcomere length in humans has been so far been performed only in static positions and under highly controlled experimental conditions (Llewellyn et al., 2008; Sanchez et al., 2015). Instead, human sarcomere length estimation (achieved by dividing GM measured fascicle length for a fixed sarcomere number) in dynamic contractions provided an indirect measure of sarcomere operating range during squat jump, countermovement jump, and DJ (Fukashiro et al., 2005, 2006; Kurokawa et al., 2003). The results of these studies showed that sarcomeres operate in the ascending limb of their length-tension (L-T) relationship in all types of jumps, and particularly so in DJ. However, most of the available observations on sarcomere and muscle fascicle behavior were made in condition of constant gravity. Thus, in order to understand how sarcomere and muscle fascicle length are regulated in variable gravity conditions, we performed experiments in a parabolic flight, involving variable gravity levels, ranging from about zero-g to about double the Earth's gravity (1 g; Waldvogel et al., 2021). Specifically, the aims of the present study were as follows: 1. To investigate the ability of the neuromuscular system in regulating fascicle length in response to conditions of variable gravity. 2. To estimate sarcomere operative length in the different DJ phases, in order to calculate its theoretical force production and its possible modulation in conditions of variable gravity. We hypothesized that muscle fascicles would be differentially regulated in different gravity conditions compared to 1 g, particularly in anticipation of landing and re-bouncing in unknown gravity levels. In addition, we hypothesized that sarcomeres would operate in the upper part of the ascending limb of their L-T relationship, possibly lengthening during the braking phase (especially in hyper-gravity) while operating quasi-isometrically in 1 g.},
  language  = {en}
}
@masterthesis{Khalaimova2021,
  type      = {Bachelor Thesis},
  author    = {Khalaimova, Karina},
  title     = {Neuerfindung der Ligaturen},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {43 Seiten},
  year      = {2021},
  abstract  = {Gegenstand des Projekts ist, Ligaturen als erweiterte Mittel der Informations{\"u}bertragung einzusetzen. Ligaturen als zus{\"a}tzliches Instrument sollen die visuelle Komponente des Textes unterst{\"u}tzen, ihm die gewisse Frische einhauchen und ihn hiermit insgesamt sichtbarer, origineller und moderner machen. Der Einsatzbereich erstreckt sich hierbei in die verschiedensten Bereiche hin {\"u}ber Design und Werbung, als auch im Handel oder in sozialen Bereichen. Hierbei kann eine große Anzahl an W{\"o}rtern neue Formen annehmen und mithin an neuem Leben und Bedeutung gewinnen, was sicherlich die allgemeinen Sprachmittel bereichern wird. Auf einer historischen Basis und mit Hilfe der Dekonstruktion wurden neue Formen der Ligaturen geschaffen — seltsame, kontroverse, auff{\"a}llige und einzigartige.},
  language  = {de}
}
@masterthesis{Muehl2021,
  type      = {Bachelor Thesis},
  author    = {M{\"u}hl, Leonie},
  title     = {Neues Erscheinungsbild f{\"u}r den APX: Redesign des LVR - Arch{\"a}ologischen Park Xanten und des R{\"o}mermuseums},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {90 Seiten},
  year      = {2021},
  abstract  = {Der Arch{\"a}ologische Park Xanten (APX) gilt als Deutschlands einziger arch{\"a}ologischer Freiluftpark. Er zeichnet sich im Verbund mit dem R{\"o}mermuseum durch seine Lage auf dem historischen Grund einer r{\"o}mischen Metropole und seine kontinuierliche Forschungsaktivit{\"a}t aus und bietet so ein einzigartiges Umfeld von kultureller Relevanz. Ziel dieses Projektes war es, ein neues Erscheinungsbild zu entwickeln, welches klar die Thematik des Parks in den Medien erkennbar macht. Das Corporate Design dient dazu, die Inhalte des Verbundes in einem einheitlichen System medien{\"u}bergreifend zu pr{\"a}sentieren. Das Design unterst{\"u}tzt den APX in seiner Funktion als Begegnungs- und Bildungsst{\"a}tte. Aufgrund dessen ist es im Hinblick auf das Ziel relevant, das Interesse an Kulturgeschichte und Forschung zu wecken.},
  language  = {de}
}
@article{Golland2021,
  author    = {Golland, Alexander},
  title     = {Neuregelungen zum Datenschutz: Ein Update f{\"u}r Website-Betreiber. Reform des Telekom-munikations- und Telemedienrechts verabschiedet},
  series = {NWB Rechnungswesen - BBK},
  journal   = {NWB Rechnungswesen - BBK},
  number    = {14},
  isbn      = {0340-9848},
  pages     = {672 -- 674},
  year      = {2021},
  language  = {de}
}
@article{AlbannaConzenWeissetal.2021,
  author    = {Albanna, Walid and Conzen, Catharina and Weiss, Miriam and Seyfried, Katharina and Kotliar, Konstantin and Schmidt, Tobias Philip and Kuerten, David and Hescheler, J{\"u}rgen and Bruecken, Anne and Schmidt-Trucks{\"a}ss, Arno and Neumaier, Felix and Wiesmann, Martin and Clusmann, Hans and Schubert, Gerrit Alexander},
  title     = {Non-invasive assessment of neurovascular coupling after aneurysmal subarachnoid hemorrhage: a prospective observational trial using retinal vessel analysis},
  series = {Frontiers in Neurology},
  volume    = {12},
  journal   = {Frontiers in Neurology},
  number    = {12},
  issn      = {1664-2295},
  doi       = {10.3389/fneur.2021.690183},
  pages     = {1 -- 15},
  year      = {2021},
  abstract  = {Delayed cerebral ischemia (DCI) is a common complication after aneurysmal subarachnoid hemorrhage (aSAH) and can lead to infarction and poor clinical outcome. The underlying mechanisms are still incompletely understood, but animal models indicate that vasoactive metabolites and inflammatory cytokines produced within the subarachnoid space may progressively impair and partially invert neurovascular coupling (NVC) in the brain. Because cerebral and retinal microvasculature are governed by comparable regulatory mechanisms and may be connected by perivascular pathways, retinal vascular changes are increasingly recognized as a potential surrogate for altered NVC in the brain. Here, we used non-invasive retinal vessel analysis (RVA) to assess microvascular function in aSAH patients at different times after the ictus.},
  language  = {en}
}
@article{MonakhovaDiehl2021,
  author    = {Monakhova, Yulia and Diehl, Bernd W.K.},
  title     = {Novel approach of qNMR workflow by standardization using 2H integral: Application to any intrinsic calibration standard},
  series = {Talanta},
  volume    = {222},
  journal   = {Talanta},
  number    = {Article number: 121504},
  publisher = {Elsevier},
  isbn      = {0039-9140},
  doi       = {10.1016/j.talanta.2020.121504},
  year      = {2021},
  abstract  = {Quantitative nuclear magnetic resonance (qNMR) is routinely performed by the internal or external standardization. The manuscript describes a simple alternative to these common workflows by using NMR signal of another active nuclei of calibration compound. For example, for any arbitrary compound quantification by NMR can be based on the use of an indirect concentration referencing that relies on a solvent having both 1H and 2H signals. To perform high-quality quantification, the deuteration level of the utilized deuterated solvent has to be estimated. In this contribution the new method was applied to the determination of deuteration levels in different deuterated solvents (MeOD, ACN, CDCl3, acetone, benzene, DMSO-d6). Isopropanol-d6, which contains a defined number of deuterons and protons, was used for standardization. Validation characteristics (precision, accuracy, robustness) were calculated and the results showed that the method can be used in routine practice. Uncertainty budget was also evaluated. In general, this novel approach, using standardization by 2H integral, benefits from reduced sample preparation steps and uncertainties, and can be applied in different application areas (purity determination, forensics, pharmaceutical analysis, etc.).},
  language  = {en}
}
@inproceedings{KronigerHorikawaFunkeetal.2021,
  author    = {Kroniger, Daniel and Horikawa, Atsushi and Funke, Harald and Pf{\"a}ffle, Franziska},
  title     = {Numerical investigation of micromix hydrogen flames at different combustor pressure levels},
  series = {Proceedings of the International Conference on Power Engineering 2021},
  booktitle = {Proceedings of the International Conference on Power Engineering 2021},
  pages     = {4 Seiten},
  year      = {2021},
  abstract  = {This study investigates the influence of pressure on the temperature distribution of the micromix (MMX) hydrogen flame and the NOx emissions. A steady computational fluid dynamic (CFD) analysis is performed by simulating a reactive flow with a detailed chemical reaction model. The numerical analysis is validated based on experimental investigations. A quantitative correlation is parametrized based on the numerical results. We find, that the flame initiation point shifts with increasing pressure from anchoring behind a downstream located bluff body towards anchoring upstream at the hydrogen jet. The numerical NOx emissions trend regarding to a variation of pressure is in good agreement with the experimental results. The pressure has an impact on both, the residence time within the maximum temperature region and on the peak temperature itself. In conclusion, the numerical model proved to be adequate for future prototype design exploration studies targeting on improving the operating range.},
  language  = {en}
}
@incollection{Kotliar2021,
  author    = {Kotliar, Konstantin},
  title     = {Ocular rigidity: clinical approach},
  series = {Ocular Rigidity, Biomechanics and Hydrodynamics of the Eye},
  booktitle = {Ocular Rigidity, Biomechanics and Hydrodynamics of the Eye},
  editor    = {Pallikaris, I. and Tsilimbaris, M. K. and Dastiridou, A. I.},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-64422-2},
  doi       = {10.1007/978-3-030-64422-2_2},
  pages     = {15 -- 43},
  year      = {2021},
  abstract  = {The term ocular rigidity is widely used in clinical ophthalmology. Generally it is assumed as a resistance of the whole eyeball to mechanical deformation and relates to biomechanical properties of the eye and its tissues. Basic principles and formulas for clinical tonometry, tonography and pulsatile ocular blood flow measurements are based on the concept of ocular rigidity. There is evidence for altered ocular rigidity in aging, in several eye diseases and after eye surgery. Unfortunately, there is no consensual view on ocular rigidity: it used to make a quite different sense for different people but still the same name. Foremost there is no clear consent between biomechanical engineers and ophthalmologists on the concept. Moreover ocular rigidity is occasionally characterized using various parameters with their different physical dimensions. In contrast to engineering approach, clinical approach to ocular rigidity claims to characterize the total mechanical response of the eyeball to its deformation without any detailed considerations on eye morphology or material properties of its tissues. Further to the previous chapter this section aims to describe clinical approach to ocular rigidity from the perspective of an engineer in an attempt to straighten out this concept, to show its advantages, disadvantages and various applications.},
  language  = {en}
}
@masterthesis{Koc2021,
  type      = {Bachelor Thesis},
  author    = {Koc, {\"O}zge Fethiye},
  title     = {OFEKO: Lehrmaterial f{\"u}r sehbehinderte Kinder},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {117 Seiten},
  year      = {2021},
  abstract  = {In einer Mischklasse, bestehend aus sehenden und nicht-sehenden Kindern, welche nicht schriftlich oder spielerisch miteinander kommunizieren k{\"o}nnen, gehen einige soziale Aspekte und Lern{\"u}bungen verloren. Partnerarbeiten und das gegenseitige Kontrollieren der Richtigkeit, beispielsweise bei der Anwendung von Satzzeichen, sind M{\"o}glichkeiten, welche die Kinder ohne ein gemeinsames Material nicht wahrnehmen k{\"o}nnen. Diese Arbeit erm{\"o}glicht ein gemeinsames Arbeiten aller Kinder durch dasselbe Material. Hierf{\"u}r dienen dreidimensionale Objekte, welche im STL-Dateiformat zur Verf{\"u}gung stehen. Es eignet sich f{\"u}r schriftliche und geografische Arbeiten. Des Weiteren ist ein Memory-Spiel enthalten, welches ebenso von sehenden und nicht-sehenden Kinder gespielt werden kann. Diese STLs k{\"o}nnen weltweit verschickt werden, sodass diese beliebig mit einem 3D-Drucker gedruckt werden k{\"o}nnen.},
  language  = {de}
}
@incollection{JordanKatzPieper2021,
  author    = {Jordan, Frank and Katz, Christiane and Pieper, Martin},
  title     = {Online-Kollaboration in der Mathematik: Ein Design-Based-Research-Projekt},
  series = {Forschungsimpulse f{\"u}r hybrides Lehren und Lernen an Hochschulen},
  booktitle = {Forschungsimpulse f{\"u}r hybrides Lehren und Lernen an Hochschulen},
  publisher = {TH K{\"o}ln},
  address   = {K{\"o}ln},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:832-cos4-9465},
  pages     = {245 -- 261},
  year      = {2021},
  abstract  = {Die Studie er{\"o}rtert anhand eines Fallbeispiels aus der Mathematik f{\"u}r Ingenieur*innen, wie didaktische Gestaltungsprinzipien f{\"u}r Soziale Pr{\"a}senz, Kollaboration und das L{\"o}sen von praxisnahen Problemen mit mathematischem Denken in einer Online-Umgebung aussehen k{\"o}nnen. Hierf{\"u}r zieht der Beitrag den forschungsmethodologischen Rahmen Design-Based Research (DBR) hinzu und berichtet {\"u}ber Zwischenergebnisse. DBR wird an dieser Stelle als eine systematische Herangehensweise an kurzfristige Lehrver{\"a}nderungen und als Chance auf dem Weg zu einer neuen Hochschullehre nach der COVID-19-Pandemie dargestellt, die theoretische und empirische Erkenntnisse mit Praxisverkn{\"u}pfung und -relevanz vereint.},
  language  = {de}
}
@inproceedings{FiedlerGottschlichMuellerMelcher2021,
  author    = {Fiedler, Gerda and Gottschlich-M{\"u}ller, Birgit and Melcher, Karin},
  title     = {Online-Pr{\"u}fungen mit STACK Aufgaben},
  series = {Tagungsband ASIM Workshop STS/GMMS/EDU 2021},
  booktitle = {Tagungsband ASIM Workshop STS/GMMS/EDU 2021},
  editor    = {Liu-Henke, Xiaobo and Durak, Umut},
  publisher = {ARGESIM Verlag},
  address   = {Wien},
  isbn      = {978-3-901608-69-8},
  doi       = {10.11128/arep.45},
  pages     = {6 Seiten},
  year      = {2021},
  abstract  = {Wir stellen hier exemplarisch STACK Aufgaben vor, die frei von der Problematik sind, welche sich durch diverse Kommunikationswege und (webbasierte) Computer Algebra Systeme (CAS) ergibt. Daher sind sie insbesondere f{\"u}r eine Open-Book Online Pr{\"u}fung geeignet, da eine faire Pr{\"u}fungssituation gew{\"a}hrleistet werden kann.},
  language  = {de}
}
@inproceedings{HandschuhStollenwerkBorchert2021,
  author    = {Handschuh, Nils and Stollenwerk, Dominik and Borchert, J{\"o}rg},
  title     = {Operation of thermal storage power plants under high renewable grid penetration},
  series = {NEIS 2021: Conference on Sustainable Energy Supply and Energy Storage Systems},
  booktitle = {NEIS 2021: Conference on Sustainable Energy Supply and Energy Storage Systems},
  publisher = {VDE Verlag},
  address   = {Berlin},
  isbn      = {978-3-8007-5651-3},
  pages     = {261 -- 265},
  year      = {2021},
  abstract  = {The planned coal phase-out in Germany by 2038 will lead to the dismantling of power plants with a total capacity of approx. 30 GW. A possible further use of these assets is the conversion of the power plants to thermal storage power plants; the use of these power plants on the day-ahead market is considerably limited by their technical parameters. In this paper, the influence of the technical boundary conditions on the operating times of these storage facilities is presented. For this purpose, the storage power plants were described as an MILP problem and two price curves, one from 2015 with a relatively low renewable penetration (33 \%) and one from 2020 with a high renewable energy penetration (51 \%) are compared. The operating times were examined as a function of the technical parameters and the critical influencing factors were investigated. The thermal storage power plant operation duration and the energy shifted with the price curve of 2020 increases by more than 25 \% compared to 2015.},
  language  = {en}
}
@inproceedings{MohanGrossMenzeletal.2021,
  author    = {Mohan, Nijanthan and Groß, Rolf Fritz and Menzel, Karsten and Theis, Fabian},
  title     = {Opportunities and Challenges in the Implementation of Building Information Modeling for Prefabrication of Heating, Ventilation and Air Conditioning Systems in Small and Medium-Sized Contracting Companies in Germany - A Case Study},
  series = {WIT Transactions on The Built Environment, Vol. 205},
  booktitle = {WIT Transactions on The Built Environment, Vol. 205},
  publisher = {WIT Press},
  address   = {Southampton},
  issn      = {1743-3509},
  doi       = {10.2495/BIM210101},
  pages     = {117 -- 126},
  year      = {2021},
  abstract  = {FEven though BIM (Building Information Modelling) is successfully implemented in most of the world, it is still in the early stages in Germany, since the stakeholders are sceptical of its reliability and efficiency. The purpose of this paper is to analyse the opportunities and obstacles to implementing BIM for prefabrication. Among all other advantages of BIM, prefabrication is chosen for this paper because it plays a vital role in creating an impact on the time and cost factors of a construction project. The project stakeholders and participants can explicitly observe the positive impact of prefabrication, which enables the breakthrough of the scepticism factor among the small-scale construction companies. The analysis consists of the development of a process workflow for implementing prefabrication in building construction followed by a practical approach, which was executed with two case studies. It was planned in such a way that, the first case study gives a first-hand experience for the workers at the site on the BIM model so that they can make much use of the created BIM model, which is a better representation compared to the traditional 2D plan. The main aim of the first case study is to create a belief in the implementation of BIM Models, which was succeeded by the execution of offshore prefabrication in the second case study. Based on the case studies, the time analysis was made and it is inferred that the implementation of BIM for prefabrication can reduce construction time, ensures minimal wastes, better accuracy, less problem-solving at the construction site. It was observed that this process requires more planning time, better communication between different disciplines, which was the major obstacle for successful implementation. This paper was carried out from the perspective of small and medium-sized mechanical contracting companies for the private building sector in Germany.},
  language  = {en}
}
@incollection{AltherrLeisePfetschetal.2021,
  author    = {Altherr, Lena and Leise, Philipp and Pfetsch, Marc E. and Schmitt, Andreas},
  title     = {Optimal design of resilient technical systems on the example of water supply systems},
  series = {Mastering Uncertainty in Mechanical Engineering},
  booktitle = {Mastering Uncertainty in Mechanical Engineering},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-030-78356-3},
  pages     = {429 -- 433},
  year      = {2021},
  language  = {en}
}
@inproceedings{SchoutetensDachwaldHeiligers2021,
  author    = {Schoutetens, Frederic and Dachwald, Bernd and Heiligers, Jeannette},
  title     = {Optimisation of photon-sail trajectories in the alpha-centauri system using evolutionary neurocontrol},
  series = {8th ICATT (International Conference on Astrodynamics Tools and Techniques) 23 - 25 June 2021, Virtual},
  booktitle = {8th ICATT (International Conference on Astrodynamics Tools and Techniques) 23 - 25 June 2021, Virtual},
  pages     = {1 -- 15},
  year      = {2021},
  abstract  = {With the increased interest for interstellar exploration after the discovery of exoplanets and the proposal by Breakthrough Starshot, this paper investigates the optimisation of photon-sail trajectories in Alpha Centauri. The prime objective is to find the optimal steering strategy for a photonic sail to get captured around one of the stars after a minimum-time transfer from Earth. By extending the idea of the Breakthrough Starshot project with a deceleration phase upon arrival, the mission's scientific yield will be increased. As a secondary objective, transfer trajectories between the stars and orbit-raising manoeuvres to explore the habitable zones of the stars are investigated. All trajectories are optimised for minimum time of flight using the trajectory optimisation software InTrance. Depending on the sail technology, interstellar travel times of 77.6-18,790 years can be achieved, which presents an average improvement of 30\% with respect to previous work. Still, significant technological development is required to reach and be captured in the Alpha-Centauri system in less than a century. Therefore, a fly-through mission arguably remains the only option for a first exploratory mission to Alpha Centauri, but the enticing results obtained in this work provide perspective for future long-residence missions to our closest neighbouring star system.},
  language  = {en}
}
@article{HugenrothBorchardtRitteretal.2021,
  author    = {Hugenroth, Kristin and Borchardt, Ralf and Ritter, Philine and Groß‑Hardt, Sascha and Meyns, Bart and Verbelen, Tom and Steinseifer, Ulrich and Kaufmann, Tim A. S. and Engelmann, Ulrich M.},
  title     = {Optimizing cerebral perfusion and hemodynamics during cardiopulmonary bypass through cannula design combining in silico, in vitro and in vivo input},
  series = {Scientific Reports},
  volume    = {11},
  journal   = {Scientific Reports},
  number    = {Art. No. 16800},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-021-96397-2},
  pages     = {1 -- 12},
  year      = {2021},
  abstract  = {Cardiopulmonary bypass (CPB) is a standard technique for cardiac surgery, but comes with the risk of severe neurological complications (e.g. stroke) caused by embolisms and/or reduced cerebral perfusion. We report on an aortic cannula prototype design (optiCAN) with helical outflow and jet-splitting dispersion tip that could reduce the risk of embolic events and restores cerebral perfusion to 97.5\% of physiological flow during CPB in vivo, whereas a commercial curved-tip cannula yields 74.6\%. In further in vitro comparison, pressure loss and hemolysis parameters of optiCAN remain unaffected. Results are reproducibly confirmed in silico for an exemplary human aortic anatomy via computational fluid dynamics (CFD) simulations. Based on CFD simulations, we firstly show that optiCAN design improves aortic root washout, which reduces the risk of thromboembolism. Secondly, we identify regions of the aortic intima with increased risk of plaque release by correlating areas of enhanced plaque growth and high wall shear stresses (WSS). From this we propose another easy-to-manufacture cannula design (opti2CAN) that decreases areas burdened by high WSS, while preserving physiological cerebral flow and favorable hemodynamics. With this novel cannula design, we propose a cannulation option to reduce neurological complications and the prevalence of stroke in high-risk patients after CPB.},
  language  = {en}
}