@article{MuellerVeggianGonoHaennietal.1978, author = {M{\"u}ller-Veggian, Mattea and Gono, Y. and Haenni, D. R. and Beuscher, H.}, title = {Side bands in ¹⁷² Hf}, series = {Proceedings of the International Conference on Nuclear Structure : Tokyo, Sept. 5 - 10, 1977 / ed. by T. Marumori. - Journal of the Physical Society of Japan ; Vol. 44, 1978 : Suppl.}, journal = {Proceedings of the International Conference on Nuclear Structure : Tokyo, Sept. 5 - 10, 1977 / ed. by T. Marumori. - Journal of the Physical Society of Japan ; Vol. 44, 1978 : Suppl.}, publisher = {Physical Soc. of Japan}, address = {Tokyo}, pages = {866}, year = {1978}, language = {en} } @article{MuellerVeggianBeuscherGonoetal.1977, author = {M{\"u}ller-Veggian, Mattea and Beuscher, H. and Gono, Y. and Lieder, R. M.}, title = {Side bands in ¹⁷² Hf}, series = {Fr{\"u}hjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft (1977)}, journal = {Fr{\"u}hjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft (1977)}, pages = {940}, year = {1977}, language = {en} } @article{MuellerVeggianHaenniGonoetal.1978, author = {M{\"u}ller-Veggian, Mattea and Haenni, D. R. and Gono, Y. and Beuscher, H.}, title = {Side bands in ¹⁷² Hf}, series = {Annual report 1977 / Institut f{\"u}r Kernphysik Kernforschungsanlage J{\"u}lich}, journal = {Annual report 1977 / Institut f{\"u}r Kernphysik Kernforschungsanlage J{\"u}lich}, publisher = {Verlag des Forschungszentrums J{\"u}lich}, address = {J{\"u}lich}, pages = {43 -- 44}, year = {1978}, language = {en} } @article{MuellerVeggianNeskakisLiederetal.1981, author = {M{\"u}ller-Veggian, Mattea and Neskakis, A. and Lieder, R. M. and Beuscher, H.}, title = {Side-bands in ¹⁸⁰ Os}, series = {International Conference Nuclear and Atomic Physics With Heay Ions : Bucharest, Romania, 9 - 12 June 1981 / European Physcial Society, Nuclear Physics Division ; The Central Institute of Physics, Romania. - (Europhysics Conference abstracts ; Vol. 5 C)}, journal = {International Conference Nuclear and Atomic Physics With Heay Ions : Bucharest, Romania, 9 - 12 June 1981 / European Physcial Society, Nuclear Physics Division ; The Central Institute of Physics, Romania. - (Europhysics Conference abstracts ; Vol. 5 C)}, publisher = {EPS}, address = {[Petit-Lancy]}, pages = {79 -- 80}, year = {1981}, language = {en} } @article{HillenEckenbachQuadfliegetal.1991, author = {Hillen, Walter and Eckenbach, W. and Quadflieg, Peter and Zaengel, Thomas T.}, title = {Signal-to-noise performance of a CsI fluorescent screen}, series = {Medical Imaging V: Image physics}, journal = {Medical Imaging V: Image physics}, isbn = {0-8194-0538-8}, pages = {120 -- 131}, year = {1991}, language = {en} } @article{HillenSchmittBockemuehl1995, author = {Hillen, Walter and Schmitt, W. and Bockem{\"u}hl, J.}, title = {Signal-to-Noise Performance of a digital dental X-ray Detector}, series = {Computer assisted radiology : proceedings of the International Symposium on Computer and Communication Systems for Image Guided Diagnosis and Therapy / CAR '95 Berlin, June 21 - 24, 1995. Ed. by H. U. Lemke}, journal = {Computer assisted radiology : proceedings of the International Symposium on Computer and Communication Systems for Image Guided Diagnosis and Therapy / CAR '95 Berlin, June 21 - 24, 1995. Ed. by H. U. Lemke}, publisher = {Springer}, address = {Berlin [u.a.]}, isbn = {3-540-59177-X}, pages = {LXXIV, 1442 S. : Ill., graph. Darst.}, year = {1995}, language = {en} } @inproceedings{BhattaraiFrotscherStaat2016, author = {Bhattarai, Aroj and Frotscher, Ralf and Staat, Manfred}, title = {Significance of fibre geometry on passive-active response of pelvic muscles to evaluate pelvic dysfunction}, series = {BioMedWomen: Proceedings of the international conference on clinical and bioengineering for women's health}, booktitle = {BioMedWomen: Proceedings of the international conference on clinical and bioengineering for women's health}, editor = {Natal Jorge, Renato}, publisher = {CRC Press}, address = {Boca Raton}, isbn = {978-1-138-02910-1}, pages = {185 -- 188}, year = {2016}, language = {en} } @article{SchoeningKloockKnobbeetal.2004, author = {Sch{\"o}ning, Michael Josef and Kloock, Joachim P. and Knobbe, D.-T. and R{\"a}de, J. and Keusgen, M.}, title = {Silicon field-effect biosensor for cyanide detection}, series = {Technical digest of the 10th International Meeting on Chemical Sensors, July 11 - 14, 2004, Tsukuba, Japan / Japan Association of Chemical Sensors}, journal = {Technical digest of the 10th International Meeting on Chemical Sensors, July 11 - 14, 2004, Tsukuba, Japan / Japan Association of Chemical Sensors}, publisher = {Japan Association of Chemical Sensors}, address = {Fukuoka}, pages = {98 -- 99}, year = {2004}, language = {en} } @article{Schoening2000, author = {Sch{\"o}ning, Michael Josef}, title = {Silicon recognizes biochemical parameters: Microchips for analytical sensor applications}, series = {American Laboratory. 32 (2000), H. 16}, journal = {American Laboratory. 32 (2000), H. 16}, isbn = {0044-7749}, pages = {24 -- 31}, year = {2000}, language = {en} } @article{Schoening2003, author = {Sch{\"o}ning, Michael Josef}, title = {Silicon-based biochemical sensors}, series = {CNI - The Center of Nanoelectronic Systems for Information Technology}, journal = {CNI - The Center of Nanoelectronic Systems for Information Technology}, publisher = {Foschungszentrum J{\"u}lich}, pages = {165 -- 170}, year = {2003}, language = {en} } @incollection{PoghossianSchoening2006, author = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Silicon-based chemical and biological field-effect sensors}, series = {Encyclopedia of Sensors. Vol. 9 S - Sk}, booktitle = {Encyclopedia of Sensors. Vol. 9 S - Sk}, publisher = {ASP, American Scientific Publ.}, address = {Stevenson Ranch, Calif.}, isbn = {1-58883-065-9}, pages = {463 -- 534}, year = {2006}, language = {en} } @article{SchoeningPoghossian2008, author = {Sch{\"o}ning, Michael Josef and Poghossian, Arshak}, title = {Silicon-based field-effect devices for (bio-)chemical sensing}, series = {International Conference on Advanced Semiconductor Devices and Microsystems, 2008. ASDAM 2008}, journal = {International Conference on Advanced Semiconductor Devices and Microsystems, 2008. ASDAM 2008}, address = {Smolenice, Slovakia}, isbn = {978-1-4244-2325-5}, pages = {31 -- 38}, year = {2008}, language = {en} } @article{SchoeningPoghossian2009, author = {Sch{\"o}ning, Michael Josef and Poghossian, Arshak}, title = {Silicon-based field-effect devices with nanostructured surfaces for bio-/chemical sensing}, series = {Semiconductor micro- and nanoelectronics : Proceedings of the Seventh International Conference , Tsakhcadzor, Armenia July 3-5 2009}, journal = {Semiconductor micro- and nanoelectronics : Proceedings of the Seventh International Conference , Tsakhcadzor, Armenia July 3-5 2009}, pages = {51 -- 53}, year = {2009}, language = {en} } @article{Schoening2003, author = {Sch{\"o}ning, Michael Josef}, title = {Silicon-based field-effect structures - From dielectrics to bioelectronics}, series = {Dielectrics in emerging technologies : proceedings of the international symposium ; [papers presented at the First International Symposium on Science and Technology of Dielectrics in Emerging Fields held from 27th April to 2nd May 2003 in Paris, France] / sponsoring divisions: Dielectric Science and Technology, Electronics. Ed.: D. Misra.}, journal = {Dielectrics in emerging technologies : proceedings of the international symposium ; [papers presented at the First International Symposium on Science and Technology of Dielectrics in Emerging Fields held from 27th April to 2nd May 2003 in Paris, France] / sponsoring divisions: Dielectric Science and Technology, Electronics. Ed.: D. Misra.}, publisher = {Electrochemical Society}, address = {Pennington, NJ}, isbn = {1-56677-346-6}, pages = {31 -- 37}, year = {2003}, language = {en} } @article{JildehWagnerSchoeningetal.2015, author = {Jildeh, Zaid B. and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Pieper, Martin}, title = {Simulating the electromagnetic-thermal treatment of thin aluminium layers for adhesion improvement}, series = {Physica status solidi (a)}, volume = {Vol. 212}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201431893}, pages = {1234 -- 1241}, year = {2015}, abstract = {A composite layer material used in packaging industry is made from joining layers of different materials using an adhesive. An important processing step in the production of aluminium-containing composites is the surface treatment and consequent coating of adhesive material on the aluminium surface. To increase adhesion strength between aluminium layer and the adhesive material, the foil is heat treated. For efficient heating, induction heating was considered as state-of-the-art treatment process. Due to the complexity of the heating process and the unpredictable nature of the heating source, the control of the process is not yet optimised. In this work, a finite element analysis of the process was established and various process parameters were studied. The process was simplified and modelled in 3D. The numerical model contains an air domain, an aluminium layer and a copper coil fitted with a magnetic field concentrating material. The effect of changing the speed of the aluminium foil (or rolling speed) was studied with the change of the coil current. Statistical analysis was used for generating a general control equation of coil current with changing rolling speed.}, language = {en} } @inproceedings{KremersPieper2015, author = {Kremers, Alexander and Pieper, Martin}, title = {Simulation and Verification of Bionic Heat Exchangers with COMSOL Multiphysics® Software}, series = {COMSOL Conference 2015 User Presentations ; COMSOL Conference 2015 Grenoble October 14 - 16, 2015 - World Trade Center, Grenoble, France}, booktitle = {COMSOL Conference 2015 User Presentations ; COMSOL Conference 2015 Grenoble October 14 - 16, 2015 - World Trade Center, Grenoble, France}, publisher = {COMSOL}, address = {G{\"o}ttingen ; Berlin}, pages = {6 Seiten}, year = {2015}, language = {en} } @article{BehbahaniNicolaiProbstetal.2007, author = {Behbahani, Mehdi and Nicolai, M. and Probst, M. and Behr, M.}, title = {Simulation of Blood Flow in a Ventricular Assist Device}, series = {inSIDE. 5 (2007), H. 1}, journal = {inSIDE. 5 (2007), H. 1}, pages = {28 -- 31}, year = {2007}, language = {en} } @inproceedings{FrotscherGossmannTemizArtmannetal.2013, author = {Frotscher, Ralf and Goßmann, Matthias and Temiz Artmann, Ayseg{\"u}l and Staat, Manfred}, title = {Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM}, series = {1st International Conference "Shell and Membrane Theories in Mechanics and Biology: From Macro- to Nanoscale Structures", Minsk, Belarus, Sept. 16-20, 2013}, booktitle = {1st International Conference "Shell and Membrane Theories in Mechanics and Biology: From Macro- to Nanoscale Structures", Minsk, Belarus, Sept. 16-20, 2013}, publisher = {Verl. d. Weißruss. Staatl. Univ.}, address = {Minsk}, organization = {International Conference Shell and Membrane Theories in Mechanics and Biology: From Macro- to Nanoscale Structures <1, 2013, Minsk>}, isbn = {978-985-553-135-8}, pages = {165 -- 167}, year = {2013}, language = {en} } @incollection{FrotscherGossmannRaatschenetal.2015, author = {Frotscher, Ralf and Goßmann, Matthias and Raatschen, Hans-J{\"u}rgen and Temiz Artmann, Ayseg{\"u}l and Staat, Manfred}, title = {Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM}, series = {Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)}, booktitle = {Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)}, publisher = {Springer}, address = {Heidelberg}, isbn = {978-3-319-02534-6 ; 978-3-319-02535-3}, pages = {187 -- 212}, year = {2015}, abstract = {We present an electromechanically coupled Finite Element model for cardiac tissue. It bases on the mechanical model for cardiac tissue of Hunter et al. that we couple to the McAllister-Noble-Tsien electrophysiological model of purkinje fibre cells. The corresponding system of ordinary differential equations is implemented on the level of the constitutive equations in a geometrically and physically nonlinear version of the so-called edge-based smoothed FEM for plates. Mechanical material parameters are determined from our own pressure-deflection experimental setup. The main purpose of the model is to further examine the experimental results not only on mechanical but also on electrophysiological level down to ion channel gates. Moreover, we present first drug treatment simulations and validate the model with respect to the experiments.}, language = {en} } @article{SchaeferMende1988, author = {Sch{\"a}fer, Horst and Mende, H. H.}, title = {Simulation of stray-field coupling between stacked grain-orientedthree-percent SiFe sheets concerning domain structure and stray-fieldprofile}, series = {IEEE Transactions on Magnetics. 24 (1988), H. 1}, journal = {IEEE Transactions on Magnetics. 24 (1988), H. 1}, isbn = {0018-9464}, pages = {631 -- 634}, year = {1988}, language = {en} } @inproceedings{BehbahaniRibleMoulinecetal.2015, author = {Behbahani, Mehdi and Rible, Sebastian and Moulinec, Charles and Fournier, Yvan and Nicolai, Mike and Crosetto, Paolo}, title = {Simulation of the FDA Centrifugal Blood Pump Using High Performance Computing}, series = {World Academy of Science, Engineering and Technology International Journal of Mechanical and Mechatronics Engineering}, volume = {9}, booktitle = {World Academy of Science, Engineering and Technology International Journal of Mechanical and Mechatronics Engineering}, number = {5}, year = {2015}, language = {en} } @inproceedings{StreunAlKaddoumParletal.2012, author = {Streun, M. and Al-Kaddoum, R. and Parl, C. and Pietrzyk, U. and Ziemons, Karl and Waasen, S. van}, title = {Simulation studies of optical photons in monolithic block scintillators}, series = {2011 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)}, booktitle = {2011 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)}, publisher = {IEEE}, address = {New York}, isbn = {978-1-4673-0120-6 (electronic ISBN)}, doi = {10.1109/NSSMIC.2011.6154621}, pages = {1380 -- 1382}, year = {2012}, abstract = {The interest in PET detectors with monolithic block scintillators is growing. In order to obtain high spatial resolutions dedicated positioning algorithms are required. But even an ideal algorithm can only deliver information which is provided by the detector. In this simulation study we investigated the light distribution on one surface of cuboid LSO scintillators of different size. Scintillators with a large aspect ratio (small footprint and large height) showed significant position information only for a minimum interaction depth of the gamma particle. The results allow a quantitative estimate for a useful aspect ratio.}, language = {en} } @inproceedings{OlderogMohrBegingetal.2021, author = {Olderog, M. and Mohr, P. and Beging, Stefan and Tsoumpas, C. and Ziemons, Karl}, title = {Simulation study on the role of tissue-scattered events in improving sensitivity for a compact time of flight compton positron emission tomograph}, series = {2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)}, booktitle = {2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)}, publisher = {IEEE}, address = {New York, NY}, isbn = {978-1-7281-7693-2}, doi = {10.1109/NSS/MIC42677.2020.9507901}, pages = {4 Seiten}, year = {2021}, abstract = {In positron emission tomography improving time, energy and spatial detector resolutions and using Compton kinematics introduces the possibility to reconstruct a radioactivity distribution image from scatter coincidences, thereby enhancing image quality. The number of single scattered coincidences alone is in the same order of magnitude as true coincidences. In this work, a compact Compton camera module based on monolithic scintillation material is investigated as a detector ring module. The detector interactions are simulated with Monte Carlo package GATE. The scattering angle inside the tissue is derived from the energy of the scattered photon, which results in a set of possible scattering trajectories or broken line of response. The Compton kinematics collimation reduces the number of solutions. Additionally, the time of flight information helps localize the position of the annihilation. One of the questions of this investigation is related to how the energy, spatial and temporal resolutions help confine the possible annihilation volume. A comparison of currently technically feasible detector resolutions (under laboratory conditions) demonstrates the influence on this annihilation volume and shows that energy and coincidence time resolution have a significant impact. An enhancement of the latter from 400 ps to 100 ps leads to a smaller annihilation volume of around 50\%, while a change of the energy resolution in the absorber layer from 12\% to 4.5\% results in a reduction of 60\%. The inclusion of single tissue-scattered data has the potential to increase the sensitivity of a scanner by a factor of 2 to 3 times. The concept can be further optimized and extended for multiple scatter coincidences and subsequently validated by a reconstruction algorithm.}, language = {en} } @inproceedings{KolditzAlbinFasseetal.2015, author = {Kolditz, Melanie and Albin, Thivaharan and Fasse, Alessandro and Br{\"u}ggemann, Gert-Peter and Abel, Dirk and Albracht, Kirsten}, title = {Simulative Analysis of Joint Loading During Leg Press Exercise for Control Applications}, series = {IFAC-PapersOnLine}, volume = {48}, booktitle = {IFAC-PapersOnLine}, number = {20}, doi = {10.1016/j.ifacol.2015.10.179}, pages = {435 -- 440}, year = {2015}, language = {en} } @article{TurekHeidenGuoetal.2010, author = {Turek, Monik and Heiden, Wolfgang and Guo, Sharon and Riesen, Alfred and Schubert, J{\"u}rgen and Zander, Willi and Kr{\"u}ger, Peter and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Simultaneous detection of cyanide and heavy metals for environmental analysis by means of µISEs}, series = {Physica Status Solidi (A). 207 (2010), H. 4}, journal = {Physica Status Solidi (A). 207 (2010), H. 4}, isbn = {1862-6300}, pages = {817 -- 823}, year = {2010}, language = {en} } @article{FuruichiYoshinobuErmelenkoetal.2001, author = {Furuichi, K. and Yoshinobu, T. and Ermelenko, T. and Mourzina, Y. and Iwasaki, H. and Sch{\"o}ning, Michael Josef}, title = {Simultaneous visualization of multiple ions by the chemical imaging sensor}, series = {Proceedings of the 5th East Asian Conference on Chemical Sensors; the 33rd Chemical Sensor Symposium : December 4 - 7, 2001, Huis Ten Bosch, Sasebo-shi, Nagasaki, Japan / Japan Association of Chemical Sensors; the Electrochemical Society of Japan}, journal = {Proceedings of the 5th East Asian Conference on Chemical Sensors; the 33rd Chemical Sensor Symposium : December 4 - 7, 2001, Huis Ten Bosch, Sasebo-shi, Nagasaki, Japan / Japan Association of Chemical Sensors; the Electrochemical Society of Japan}, publisher = {Japan Association of Chemical Sensors}, address = {Kasuga, Fukuoka-ken}, pages = {399 -- 401}, year = {2001}, language = {en} } @article{Ackermann1996, author = {Ackermann, Hans-Josef}, title = {Single chip hardware support for rasterization and texture mapping}, series = {Computers \& graphics : CAG ; an international journal of applications in computer graphics. 20 (1996), H. 4}, journal = {Computers \& graphics : CAG ; an international journal of applications in computer graphics. 20 (1996), H. 4}, isbn = {0097-8493}, pages = {503 -- 514}, year = {1996}, language = {en} } @article{DadfarCamozziDarguzyteetal.2020, author = {Dadfar, Dryed Mohammadali and Camozzi, Denise and Darguzyte, Milita and Roemhild, Karolin and Varvar{\`a}, Paola and Metselaar, Josbert and Banala, Srinivas and Straub, Marcel and G{\"u}ver, Nihan and Engelmann, Ulrich M. and Slabu, Ioana and Buhl, Miriam and Leusen, Jan van and K{\"o}gerler, Paul and Hermanns-Sachweh, Benita and Schulz, Volkmar and Kiessling, Fabian and Lammers, Twan}, title = {Size-isolation of superparamagnetic iron oxide nanoparticles improves MRI, MPI and hyperthermia performance}, series = {Journal of Nanobiotechnology}, volume = {18}, journal = {Journal of Nanobiotechnology}, number = {Article number 22}, publisher = {Nature Portfolio}, issn = {1477-3155}, doi = {10.1186/s12951-020-0580-1}, pages = {1 -- 13}, year = {2020}, abstract = {Superparamagnetic iron oxide nanoparticles (SPION) are extensively used for magnetic resonance imaging (MRI) and magnetic particle imaging (MPI), as well as for magnetic fluid hyperthermia (MFH). We here describe a sequential centrifugation protocol to obtain SPION with well-defined sizes from a polydisperse SPION starting formulation, synthesized using the routinely employed co-precipitation technique. Transmission electron microscopy, dynamic light scattering and nanoparticle tracking analyses show that the SPION fractions obtained upon size-isolation are well-defined and almost monodisperse. MRI, MPI and MFH analyses demonstrate improved imaging and hyperthermia performance for size-isolated SPION as compared to the polydisperse starting mixture, as well as to commercial and clinically used iron oxide nanoparticle formulations, such as Resovist® and Sinerem®. The size-isolation protocol presented here may help to identify SPION with optimal properties for diagnostic, therapeutic and theranostic applications.}, language = {en} } @article{SanderCzajkowskiFosteretal.2002, author = {Sander, Volker and Czajkowski, K. and Foster, I. and Kesselman, C.}, title = {SNAP: A Protocol for Negotiating Service Level Agreements and Coordinating Resource Management in Distributed Systems / Czajkowski, K. ; Foster, I. ; Kesselman, C. ; Sander, V. ; Tuecke, S.}, series = {Job Scheduling Strategies for Parallel Processing : 8th InternationalWorkshop, JSSPP 2002 Edinburgh, Scotland, UK, July 24, 2002. Revised Papers}, journal = {Job Scheduling Strategies for Parallel Processing : 8th InternationalWorkshop, JSSPP 2002 Edinburgh, Scotland, UK, July 24, 2002. Revised Papers}, publisher = {Springer}, address = {Berlin}, isbn = {3-540-00172-7}, pages = {153 -- 183}, year = {2002}, language = {en} } @article{VoegeleRuebbelkeGovorukhaetal.2019, author = {V{\"o}gele, Stefan and R{\"u}bbelke, Dirk and Govorukha, Kristina and Grajewski, Matthias}, title = {Socio-technical scenarios for energy-intensive industries: the future of steel production in Germany}, series = {Climatic Change}, journal = {Climatic Change}, publisher = {Springer}, address = {Berlin}, issn = {0165-0009}, doi = {10.1007/s10584-019-02366-0}, pages = {1 -- 16}, year = {2019}, language = {en} } @article{StaatBaroudTopcuetal.2008, author = {Staat, Manfred and Baroud, G. and Topcu, M. and Sponagel, Stefan}, title = {Soft Materials in Technology and Biology - Characteristics, Properties, and Parameter Identification}, series = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, journal = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-75408-4}, pages = {253 -- 315}, year = {2008}, language = {en} } @inproceedings{SchreiberHirtbachKraftetal.2013, author = {Schreiber, Marc and Hirtbach, Stefan and Kraft, Bodo and Steinmetzler, Andreas}, title = {Software in the city: visual guidance through large scale software projects}, series = {Software Engineering 2013 : Fachtagung des GI-Fachbereichs Softwaretechnik, 26. Februar-1. M{\"a}rz 2013 in Aachen. (GI-Edition ; 213)}, booktitle = {Software Engineering 2013 : Fachtagung des GI-Fachbereichs Softwaretechnik, 26. Februar-1. M{\"a}rz 2013 in Aachen. (GI-Edition ; 213)}, editor = {Kowalewski, Stefan}, publisher = {Ges. f{\"u}r Informatik}, address = {Bonn}, isbn = {978-3-88579-607-7 ; 978-3-88579-609-1}, pages = {213 -- 224}, year = {2013}, language = {en} } @article{VlasovMourzinaLeginetal.2002, author = {Vlasov, Y. G. and Mourzina, Y. G. and Legin, A. V. and Ermelenko, Y. E. and Schubert, J. and Sch{\"o}ning, Michael Josef and L{\"u}th, H.}, title = {Solid-state thin film sensors based on chalcogenide materials prepared by planar technology and pulsed laser deposition}, series = {Russian Journal of Applied Chemistry. 75 (2002), H. 3}, journal = {Russian Journal of Applied Chemistry. 75 (2002), H. 3}, isbn = {1070-4272}, pages = {351 -- 356}, year = {2002}, language = {en} } @article{MartinVaqueroKleefeld2020, author = {Mart{\´i}n-Vaquero, J. and Kleefeld, Andreas}, title = {Solving nonlinear parabolic PDEs in several dimensions: Parallelized ESERK codes}, series = {Journal of Computational Physics}, journal = {Journal of Computational Physics}, number = {423}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0021-9991}, doi = {10.1016/j.jcp.2020.109771}, year = {2020}, abstract = {There is a very large number of very important situations which can be modeled with nonlinear parabolic partial differential equations (PDEs) in several dimensions. In general, these PDEs can be solved by discretizing in the spatial variables and transforming them into huge systems of ordinary differential equations (ODEs), which are very stiff. Therefore, standard explicit methods require a large number of iterations to solve stiff problems. But implicit schemes are computationally very expensive when solving huge systems of nonlinear ODEs. Several families of Extrapolated Stabilized Explicit Runge-Kutta schemes (ESERK) with different order of accuracy (3 to 6) are derived and analyzed in this work. They are explicit methods, with stability regions extended, along the negative real semi-axis, quadratically with respect to the number of stages s, hence they can be considered to solve stiff problems much faster than traditional explicit schemes. Additionally, they allow the adaptation of the step length easily with a very small cost. Two new families of ESERK schemes (ESERK3 and ESERK6) are derived, and analyzed, in this work. Each family has more than 50 new schemes, with up to 84.000 stages in the case of ESERK6. For the first time, we also parallelized all these new variable step length and variable number of stages algorithms (ESERK3, ESERK4, ESERK5, and ESERK6). These parallelized strategies allow to decrease times significantly, as it is discussed and also shown numerically in two problems. Thus, the new codes provide very good results compared to other well-known ODE solvers. Finally, a new strategy is proposed to increase the efficiency of these schemes, and it is discussed the idea of combining ESERK families in one code, because typically, stiff problems have different zones and according to them and the requested tolerance the optimum order of convergence is different.}, language = {en} } @article{Staat2002, author = {Staat, Manfred}, title = {Some Achievements of the European Project LISA for FEM Based Limit and Shakedown Analysis}, series = {Computational mechanics : developments and applications, 2002 : presented at the 2002 ASME Pressure Vessels and Piping Conference, Vancouver, British Columbia, Canada, August 5 - 9. / Badie, N. [ed]}, journal = {Computational mechanics : developments and applications, 2002 : presented at the 2002 ASME Pressure Vessels and Piping Conference, Vancouver, British Columbia, Canada, August 5 - 9. / Badie, N. [ed]}, publisher = {American Society of Mechanical Engineers}, address = {New York}, isbn = {0791846520}, pages = {177 -- 185}, year = {2002}, language = {en} } @article{Stulpe1994, author = {Stulpe, Werner}, title = {Some Remarks on Classical Representations of Quantum Mechanics}, series = {Foundations of Physics . 24 (1994), H. 7}, journal = {Foundations of Physics . 24 (1994), H. 7}, isbn = {1572-9516}, pages = {1089 -- 1094}, year = {1994}, language = {en} } @article{StulpeSinger1990, author = {Stulpe, Werner and Singer, Matthias}, title = {Some Remarks on the Determination of Quantum States by Measurements}, series = {Foundations of Physics Letters. 3 (1990), H. 2}, journal = {Foundations of Physics Letters. 3 (1990), H. 2}, isbn = {1572-9524}, pages = {153 -- 166}, year = {1990}, language = {en} } @article{DiktaHausmannSchmidt2002, author = {Dikta, Gerhard and Hausmann, Rolf and Schmidt, Christian}, title = {Some Simulation Results under Random Censorship Models}, pages = {1 -- 12}, year = {2002}, language = {en} } @misc{AbdelghaniMenaaObareetal.2013, author = {Abdelghani, Adnane and Menaa, Bouzid and Obare, Sherine O. and Sch{\"o}ning, Michael Josef}, title = {Special issue on nanoscale science and technology / guest eds.: Adnane Abdelghani, Bouzid Menaa, Sherine O. Obare, Michael J. Sch{\"o}ning}, series = {International journal of nanotechnology}, volume = {Vol. 10}, journal = {International journal of nanotechnology}, number = {No. 5-7}, issn = {1741-8151 (E-Journal), 1475-7435 (Print)}, pages = {373 -- 619}, year = {2013}, language = {en} } @article{TuraliyevaYeshibaevSaparbekovaetal.2016, author = {Turaliyeva, M. and Yeshibaev, A. and Saparbekova, A. and Akynova, L. and Abildayeva, R. and Sadenova, M. and Sartayeva, K. and Schieffer, Andre and Digel, Ilya}, title = {Species composition and injuriousness of stranger xylophilous fauna affecting indigenous urban dendroflora of Central Asia}, series = {Asian journal of microbiology, biotechnology \& environmental sciences : AJMBES}, volume = {18}, journal = {Asian journal of microbiology, biotechnology \& environmental sciences : AJMBES}, number = {2}, publisher = {EM International}, issn = {0972-3005}, pages = {359 -- 366}, year = {2016}, abstract = {At the present time, one of the most serious environmental problems of Central Asia and South Kazakhstan is the ongoing large-scale deterioration of principal urban tree populations. Several major centers of massive spread of invasive plant pests have been found in urban dendroflora of this region. The degree of damage of seven most wide-spread aboriginal tree species was found to range from 21.4±1.1 to 85.4±1.8\%. In particular, the integrity of the native communities of sycamore (Platanus spp.), willow (Salix spp.), poplar (Populus spp.) and elm (Ulmus spp.) is highly endangered. Our taxonomic analysis of the most dangerous tree pests of the region has revealed them as neobiontic xylophilous insects such as Cossus cossus L. (Order: Lepidoptera L.) Monochamus urussovi Fisch., Monochamus sutor L., Acanthocinus aedelis L. and {\~N}etonia aureate L. (Order: Coleoptera L.). We relate the origin of this threatening trend with the import of industrial wood in the mid 90’s of the last century that was associated with high degree of the constructional work in the region. Because of the absence of efficient natural predators of the pest species, the application of microbiological methods of the pest control and limitation is suggested.}, language = {en} } @article{BoeckerKuwertLangenetal.1994, author = {Boecker, Henning and Kuwert, Torsten and Langen, Karl-J. and Lange, Herwig W. and Czech, Norbert and Ziemons, Karl and Herzog, Hans and Shikare, Shekar and Weindl, Anton and Feinendegen, Ludwig E.}, title = {SPECT with HMPAO compared to PET with FDG in Huntington disease}, series = {Journal of Computer Assisted Tomography}, volume = {18}, journal = {Journal of Computer Assisted Tomography}, number = {4}, isbn = {1532-3145}, pages = {542 -- 548}, year = {1994}, language = {en} } @article{OberlaenderMayerGreeffetal.2018, author = {Oberl{\"a}nder, Jan and Mayer, Marlena and Greeff, Anton and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Spore-based biosensor to monitor the microbicidal efficacy of gaseous hydrogen peroxide sterilization processes}, series = {Biosensors and Bioelectronics}, volume = {104}, journal = {Biosensors and Bioelectronics}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0956-5663}, doi = {10.1016/j.bios.2017.12.045}, pages = {87 -- 94}, year = {2018}, abstract = {In this work, a spore-based biosensor is evaluated to monitor the microbicidal efficacy of sterilization processes applying gaseous hydrogen peroxide (H2O2). The sensor is based on interdigitated electrode structures (IDEs) that have been fabricated by means of thin-film technologies. Impedimetric measurements are applied to study the effect of sterilization process on spores of Bacillus atrophaeus. This resilient microorganism is commonly used in industry to proof the sterilization efficiency. The sensor measurements are accompanied by conventional microbiological challenge tests, as well as morphological characterizations with scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The sensor measurements are correlated with the microbiological test routines. In both methods, namely the sensor-based and microbiological one, a tailing effect has been observed. The results are evaluated and discussed in a three-dimensional calibration plot demonstrating the sensor's suitability to enable a rapid process decision in terms of a successfully performed sterilization.}, language = {en} } @inproceedings{KohlSchmidtsKloeseretal.2021, author = {Kohl, Philipp and Schmidts, Oliver and Kl{\"o}ser, Lars and Werth, Henri and Kraft, Bodo and Z{\"u}ndorf, Albert}, title = {STAMP 4 NLP - an agile framework for rapid quality-driven NLP applications development}, series = {Quality of Information and Communications Technology. QUATIC 2021}, booktitle = {Quality of Information and Communications Technology. QUATIC 2021}, publisher = {Springer}, address = {Cham}, isbn = {978-3-030-85346-4}, doi = {10.1007/978-3-030-85347-1_12}, pages = {156 -- 166}, year = {2021}, abstract = {The progress in natural language processing (NLP) research over the last years, offers novel business opportunities for companies, as automated user interaction or improved data analysis. Building sophisticated NLP applications requires dealing with modern machine learning (ML) technologies, which impedes enterprises from establishing successful NLP projects. Our experience in applied NLP research projects shows that the continuous integration of research prototypes in production-like environments with quality assurance builds trust in the software and shows convenience and usefulness regarding the business goal. We introduce STAMP 4 NLP as an iterative and incremental process model for developing NLP applications. With STAMP 4 NLP, we merge software engineering principles with best practices from data science. Instantiating our process model allows efficiently creating prototypes by utilizing templates, conventions, and implementations, enabling developers and data scientists to focus on the business goals. Due to our iterative-incremental approach, businesses can deploy an enhanced version of the prototype to their software environment after every iteration, maximizing potential business value and trust early and avoiding the cost of successful yet never deployed experiments.}, language = {en} } @article{SchaeferRessSpahnetal.1998, author = {Sch{\"a}fer, Horst and Ress, H. R. and Spahn, W. and Ebel, R. (u.a.)}, title = {Start of misfit relaxation in GaAs-ZnSe heterostructures}, series = {Journal of Crystal Growth. 184-185 (1998)}, journal = {Journal of Crystal Growth. 184-185 (1998)}, isbn = {0022-0248}, pages = {90 -- 94}, year = {1998}, language = {en} } @article{HorstmannBialonskiNoenningetal.2010, author = {Horstmann, Marie-Therese and Bialonski, Stephan and Noenning, Nina and Mai, Heinke and Prusseit, Jens and Wellmer, J{\"o}rg and Hinrichs, Hermann and Lehnertz, Klaus}, title = {State dependent properties of epileptic brain networks: Comparative graph-theoretical analyses of simultaneously recorded EEG and MEG}, series = {Clinical Neurophysiology}, volume = {121}, journal = {Clinical Neurophysiology}, number = {2}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1388-2457}, doi = {10.1016/j.clinph.2009.10.013}, pages = {172 -- 185}, year = {2010}, abstract = {Objective To investigate whether functional brain networks of epilepsy patients treated with antiepileptic medication differ from networks of healthy controls even during the seizure-free interval. Methods We applied different rules to construct binary and weighted networks from EEG and MEG data recorded under a resting-state eyes-open and eyes-closed condition from 21 epilepsy patients and 23 healthy controls. The average shortest path length and the clustering coefficient served as global statistical network characteristics. Results Independent on the behavioral condition, epileptic brains exhibited a more regular functional network structure. Similarly, the eyes-closed condition was characterized by a more regular functional network structure in both groups. The amount of network reorganization due to behavioral state changes was similar in both groups. Consistent findings could be achieved for networks derived from EEG but hardly from MEG recordings, and network construction rules had a rather strong impact on our findings. Conclusions Despite the locality of the investigated processes epileptic brain networks differ in their global characteristics from non-epileptic brain networks. Further methodological developments are necessary to improve the characterization of disturbed and normal functional networks. Significance An increased regularity and a diminished modulation capability appear characteristic of epileptic brain networks.}, language = {en} } @article{LehnertzMormannOsterhageetal.2007, author = {Lehnertz, Klaus and Mormann, Florian and Osterhage, Hannes and Andy, M{\"u}ller and Prusseit, Jens and Chernihovskyi, Anton and Staniek, Matth{\"a}us and Krug, Dieter and Bialonski, Stephan and Elger, Christian E.}, title = {State-of-the-art of seizure prediction}, series = {Journal of Clinical Neurophysiology}, volume = {24}, journal = {Journal of Clinical Neurophysiology}, number = {2}, issn = {1537-1603}, doi = {10.1097/WNP.0b013e3180336f16}, pages = {147 -- 153}, year = {2007}, language = {en} } @article{BaringhausGaigallThiele2018, author = {Baringhaus, Ludwig and Gaigall, Daniel and Thiele, Jan Philipp}, title = {Statistical inference for L²-distances to uniformity}, series = {Computational Statistics}, volume = {2018}, journal = {Computational Statistics}, number = {33}, publisher = {Springer}, address = {Berlin}, issn = {1613-9658}, doi = {10.1007/s00180-018-0820-0}, pages = {1863 -- 1896}, year = {2018}, abstract = {The paper deals with the asymptotic behaviour of estimators, statistical tests and confidence intervals for L²-distances to uniformity based on the empirical distribution function, the integrated empirical distribution function and the integrated empirical survival function. Approximations of power functions, confidence intervals for the L²-distances and statistical neighbourhood-of-uniformity validation tests are obtained as main applications. The finite sample behaviour of the procedures is illustrated by a simulation study.}, language = {en} } @article{HeinrichBlumBussmannetal.2002, author = {Heinrich, U. and Blum, A. and Bussmann, N. and Engels, R. and Kemmerling, G. and Weber, S. and Ziemons, Karl}, title = {Statistical studies on the light output and energy resolution of small LSO single crystals with different surface treatments combined with various reflector materials}, series = {Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, volume = {486}, journal = {Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, number = {1-2}, issn = {0168-9002}, pages = {60 -- 66}, year = {2002}, abstract = {The optimization of light output and energy resolution of scintillators is of special interest for the development of high resolution and high sensitivity PET. The aim of this work is to obtain statistically reliable results concerning optimal surface treatment of scintillation crystals and the selection of reflector material. For this purpose, raw, mechanically polished and etched LSO crystals (size 2×2×10 mm3) were combined with various reflector materials (Teflon tape, Teflon matrix, BaSO4) and exposed to a 22Na source. In order to ensure the statistical reliability of the results, groups of 10 LSO crystals each were measured for all combinations of surface treatment and reflector material. Using no reflector material the light output increased up to 551±35\% by mechanical polishing the surface compared to 100±5\% for raw crystals. Etching the surface increased the light output to 441±29\%. The untreated crystals had an energy resolution of 24.6±4.0\%. By mechanical polishing the surface it was possible to achieve an energy resolution of 13.2±0.8\%, by etching of 14.8±0.7\%. In combination with BaSO4 as reflector material the maximum increase of light output has been established to 932±57\% for mechanically polished and 895±61\% for etched crystals. The combination with BaSO4 also caused the best improvement of the energy resolution up to 11.6±0.2\% for mechanically polished and 12.2±0.3\% for etched crystals. Relating to the light output there was no significant statistical difference between the two surface treatments in combination with BaSO4. In contrast to this, the statistical results of the energy resolution have shown the combination of mechanical polishing and BaSO4 as the optimum.}, language = {en} } @book{Artmann2011, author = {Artmann, Gerhard}, title = {Stem cell engineering : principles and applications / Gerhard M. Artmann ... eds.}, publisher = {Springer}, address = {Berlin [u.a.]}, isbn = {978-3-642-11864-7}, pages = {XLI, 541 S. : Ill., graph. Darst.}, year = {2011}, language = {en} } @book{KaminskyKallweitWeberetal.2006, author = {Kaminsky, Radoslav and Kallweit, Stephan and Weber, Hans-Joachim and Simons, Antoine and Verdonck, Pascal}, title = {Stereo high speed PIV measurements behind two different artificial heart valves}, pages = {9 S. : Ill., graph. Darst.}, year = {2006}, language = {en} } @inproceedings{StaatTran2022, author = {Staat, Manfred and Tran, Ngoc Trinh}, title = {Strain based brittle failure criteria for rocks}, series = {Proceedings of (NACOME2022) The 11th National Conference on Mechanics, Vol. 1. Solid Mechanics, Rock Mechanics, Artificial Intelligence, Teaching and Training}, booktitle = {Proceedings of (NACOME2022) The 11th National Conference on Mechanics, Vol. 1. Solid Mechanics, Rock Mechanics, Artificial Intelligence, Teaching and Training}, publisher = {Nha xuat ban Khoa hoc tu nhien va Cong nghe (Verlag Naturwissenschaft und Technik)}, address = {Hanoi}, isbn = {978-604-357-084-7}, pages = {500 -- 509}, year = {2022}, abstract = {When confining pressure is low or absent, extensional fractures are typical, with fractures occurring on unloaded planes in rock. These "paradox" fractures can be explained by a phenomenological extension strain failure criterion. In the past, a simple empirical criterion for fracture initiation in brittle rock has been developed. But this criterion makes unrealistic strength predictions in biaxial compression and tension. A new extension strain criterion overcomes this limitation by adding a weighted principal shear component. The weight is chosen, such that the enriched extension strain criterion represents the same failure surface as the Mohr-Coulomb (MC) criterion. Thus, the MC criterion has been derived as an extension strain criterion predicting failure modes, which are unexpected in the understanding of the failure of cohesive-frictional materials. In progressive damage of rock, the most likely fracture direction is orthogonal to the maximum extension strain. The enriched extension strain criterion is proposed as a threshold surface for crack initiation CI and crack damage CD and as a failure surface at peak P. Examples show that the enriched extension strain criterion predicts much lower volumes of damaged rock mass compared to the simple extension strain criterion.}, language = {en} } @article{ZiemonsBerghoffLanskeetal.1988, author = {Ziemons, Karl and Berghoff, G. and Lanske, D. and Schultze, K.}, title = {Strangeness production in deep inelastic muon-nucleon scattering}, series = {Verhandlungen der Deutschen Physikalischen Gesellschaft}, volume = {23}, journal = {Verhandlungen der Deutschen Physikalischen Gesellschaft}, number = {5}, isbn = {0420-0195}, pages = {T309 -- T309}, year = {1988}, language = {en} } @article{KeusgenSchoening2004, author = {Keusgen, M. and Sch{\"o}ning, Michael Josef}, title = {Strategies for biosensoric detection of potential drugs in nature}, series = {Biomedizinische Technik. 49 (2004), H. 2}, journal = {Biomedizinische Technik. 49 (2004), H. 2}, isbn = {0932-4666}, pages = {1004 -- 1005}, year = {2004}, language = {en} } @article{OberlaenderKirchnerKeusgenetal.2015, author = {Oberl{\"a}nder, Jan and Kirchner, Patrick and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Strategies in developing thin-film sensors for monitoring aseptic food processes : Theoretical considerations and investigations of passivation materials}, series = {Electrochimica Acta}, volume = {183}, journal = {Electrochimica Acta}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0013-4686}, doi = {10.1016/j.electacta.2015.06.126}, pages = {130 -- 136}, year = {2015}, abstract = {The sterilization of packages in aseptic food processes is highly significant to maintain a consumer-safe product with extended shelf-life. Today, the sterilization of food packages is predominantly accomplished by gaseous hydrogen peroxide (H2O2) in combination with heat. In order to monitor this sterilization process, calorimetric gas sensors as differential set-up of two platinum temperature sensors representing a catalytically active (additionally deposition of MnO2) and a passive segment have been recently developed. The temperature rise of the exothermic decomposition serves as an indicator of the present H2O2 concentration. In the present work, a theoretical approach considering the sensor's thermochemistry and physical transport phenomena was formulated to evaluate the temperature rise based on the energy content of gaseous H2O2. In a further part of this work, three polymers have been analyzed with respect to their application as passivation materials. The examined polymers are photoresist SU-8, perfluoroalkoxy (PFA) and fluorinated ethylene propylene (FEP). Thermal analyses by means of differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) have been conducted to determine the operation limits of the polymers. The overall chemical resistance and stability of the polymers against the harsh environmental conditions during the sterilization process have been examined by attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR).}, language = {en} } @article{SimonisLuethWangetal.2003, author = {Simonis, A. and L{\"u}th, H. and Wang, J. and Sch{\"o}ning, Michael Josef}, title = {Strategies of miniaturised reference electrodes integrated in a silicon-based „one chip" pH sensor}, series = {Sensors. 3 (2003), H. 9}, journal = {Sensors. 3 (2003), H. 9}, isbn = {1424-8220}, pages = {330 -- 339}, year = {2003}, language = {en} } @article{SchaeferMende1987, author = {Sch{\"a}fer, Horst and Mende, H. H.}, title = {Stray field profile of grain-oriented rectangular 3\% SiFe sheets in dependence on vertical and in-plane magnetic fields}, series = {Physica Status Solidi (A). 100 (1987), H. 2}, journal = {Physica Status Solidi (A). 100 (1987), H. 2}, isbn = {0031-8965}, pages = {621 -- 632}, year = {1987}, language = {en} } @article{SchaeferLampeyMende1989, author = {Sch{\"a}fer, Horst and Lampey, H. and Mende, H. H.}, title = {Stray-field profile of single M-shaped Si-Fe transformer sheets and the resulting interaction in a stack}, series = {Physica Scripta. 39 (1989), H. 4}, journal = {Physica Scripta. 39 (1989), H. 4}, isbn = {0031-8949}, pages = {520 -- 522}, year = {1989}, language = {en} } @article{GruetersBlankDuerkopetal.1994, author = {Gr{\"u}ters, Hugo and Blank, K. and D{\"u}rkop, D. and Durchholz, M.}, title = {Strength tests of flat glass by means of four-point bending. Blank, K.; D{\"u}rkop, D.; Durchholz, M.; Gr{\"u}ters, H.}, series = {Glastechnische Berichte. Glass science and technology. 67 (1994), H. 1}, journal = {Glastechnische Berichte. Glass science and technology. 67 (1994), H. 1}, isbn = {0946-7475}, pages = {9 -- 15}, year = {1994}, language = {en} } @article{GruetersHacklWillms1990, author = {Gr{\"u}ters, Hugo and Hackl, K. and Willms, H.}, title = {Stress and strain analyses of rectangular glass plates for large deformations. Part 1. Dimensioning of rectangular plates under surface load and/or line load.}, series = {Glastechnische Berichte. 63 (1990), H. 3}, journal = {Glastechnische Berichte. 63 (1990), H. 3}, isbn = {0017-1085}, pages = {69 -- 77}, year = {1990}, language = {en} } @article{GruetersHacklWillms1990, author = {Gr{\"u}ters, Hugo and Hackl, K. and Willms, H.}, title = {Stress and strain analyses of rectangular glass plates for large deformations. Part 2. Calculation of fracture probabilities in rectangular plates under area load}, series = {Glastechnische Berichte. 63 (1990), H. 4}, journal = {Glastechnische Berichte. 63 (1990), H. 4}, isbn = {0017-1085}, pages = {93 -- 95}, year = {1990}, language = {en} } @article{FrotscherStaat2014, author = {Frotscher, Ralf and Staat, Manfred}, title = {Stresses produced by different textile mesh implants in a tissue equivalent}, series = {BioNanoMaterials}, volume = {15}, journal = {BioNanoMaterials}, number = {1-2}, publisher = {De Gruyter}, address = {Berlin}, issn = {2191-4672 (E-Journal); 2193-066X (E-Journal); 0011-8656 (Print); 1616-0177 (Print); 2193-0651 (Print)}, doi = {10.1515/bnm-2014-0003}, pages = {25 -- 30}, year = {2014}, abstract = {Two single-incision mini-slings used for treating urinary incontinence in women are compared with respect to the stresses they produce in their surrounding tissue. In an earlier paper we experimentally observed that these implants produce considerably different stress distributions in a muscle tissue equivalent. Here we perform 2D finite element analyses to compare the shear stresses and normal stresses in the tissue equivalent for the two meshes and to investigate their failure behavior. The results clearly show that the Gynecare TVT fails for increasing loads in a zipper-like manner because it gradually debonds from the surrounding tissue. Contrary to that, the tissue at the ends of the DynaMesh-SIS direct may rupture but only at higher loads. The simulation results are in good agreement with the experimental observations thus the computational model helps to interpret the experimental results and provides a tool for qualitative evaluation of mesh implants.}, language = {en} } @article{PresslerEsefeldScherretal.2010, author = {Pressler, Axel and Esefeld, Katrin and Scherr, Johannes and Ali, Mohammad and Hanssen, Henner and Kotliar, Konstantin and Lanzl, Ines and Halle, Martin and Kaemmerer, Harald and Schmidt-Trucks{\"a}ss, Arno and Hager, Alfred}, title = {Structural alterations of retinal arterioles in adults late after repair of aortic isthmic coarctation}, series = {The American Journal of Cardiology}, volume = {105}, journal = {The American Journal of Cardiology}, number = {5}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0002-9149}, doi = {10.1016/j.amjcard.2009.10.070}, pages = {740 -- 744}, year = {2010}, abstract = {Patients after coarctation repair still have an increased risk of cardiovascular or cerebrovascular events. This has been explained by the persisting hypertension and alterations in the peripheral vessels. However, involvement of the central vessels such as the retinal arteries is virtually unknown. A total of 34 patients after coarctation repair (22 men and 12 women; 23 to 58 years old, age range 0 to 32 years at surgical repair) and 34 nonhypertensive controls underwent structural and functional retinal vessel analysis. Using structural analysis, the vessel diameters were measured. Using functional analysis, the endothelium-dependent vessel dilation in response to flicker light stimulation was assessed. In the patients after coarctation repair, the retinal arteriolar diameter was significantly reduced compared to that of the controls (median 182 μm, first to third quartile 171 to 197; vs 197 μm, first to third quartile 193 to 206; p <0.001). These findings were independent of the peripheral blood pressure and age at intervention. No differences were found for venules. The functional analysis findings were not different between the patients and controls (maximum dilation 3.5\%, first to third quartile 2.1\% to 4.5\% vs 3.6\%, first to third quartile 2.2\% to 4.3\%; p = 0.81), indicating preserved autoregulative mechanisms. In conclusion, the retinal artery diameter is reduced in patients after coarctation repair, independent of their current blood pressure level and age at intervention. As a structural marker of chronic vessel damage associated with past, current, or future hypertension, retinal arteriolar narrowing has been linked to stroke incidence. These results indicate an involvement of cerebral microcirculation in aortic coarctation, despite timely repair, and might contribute to explain the increased rate of cerebrovascular events in such patients.}, language = {en} } @article{StaatHeitzer1999, author = {Staat, Manfred and Heitzer, M.}, title = {Structural Reliability Analysis of Elasto-Plastic Structures}, series = {Safety and reliability : proceedings of ESREL '99, the Tenth European Conference on Safety and Reliability, Munich-Garching, Germany, 13 - 17 September 1999 / Schu{\"e}ller, G. I.; Kafka, P. [eds]}, journal = {Safety and reliability : proceedings of ESREL '99, the Tenth European Conference on Safety and Reliability, Munich-Garching, Germany, 13 - 17 September 1999 / Schu{\"e}ller, G. I.; Kafka, P. [eds]}, publisher = {Balkema}, address = {Rotterdam}, isbn = {90-5809-109-0}, pages = {513 -- 518}, year = {1999}, language = {en} } @article{ZerlinKasischkeDigeletal.2007, author = {Zerlin, Kay and Kasischke, Nicole and Digel, Ilya and Maggakis-Kelemen, Christina and Temiz Artmann, Ayseg{\"u}l and Porst, Dariusz and Kayser, Peter and Linder, Peter and Artmann, Gerhard}, title = {Structural transition temperature of hemoglobins correlates with species' body temperature}, series = {European Biophysics Journal. 37 (2007), H. 1}, journal = {European Biophysics Journal. 37 (2007), H. 1}, isbn = {1432-1017}, pages = {1 -- 10}, year = {2007}, language = {en} } @article{MuellerVeggianBeuscherHaenni1982, author = {M{\"u}ller-Veggian, Mattea and Beuscher, H. and Haenni, D. R.}, title = {Structure of high-spin states in ¹³⁴ Ce}, series = {Annual report 1981 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: F. Gr{\"u}mmer. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 146)}, journal = {Annual report 1981 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: F. Gr{\"u}mmer. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 146)}, publisher = {Kernforschungsanlage}, address = {J{\"u}lich}, pages = {52}, year = {1982}, language = {en} } @phdthesis{Geenen2013, author = {Geenen, Eva-Maria}, title = {Studies of Epstein-Barr virus EBNA2 and its interactions with host cell factors}, publisher = {Universit{\´e} de Grenoble}, address = {Grenoble}, pages = {125 S.}, year = {2013}, language = {en} } @phdthesis{Schieffer2012, author = {Schieffer, Andre}, title = {Studies on diversity and coexistence in an experimental microbial community}, pages = {76 Bl. : Ill.}, year = {2012}, abstract = {Biodiversity and the coexistence of species have puzzled and fascinated biologists since decades and is a hotspot in todays' natural sciences. Preserving this biodiversity is a great challenge as habitats and environments underlying tremendous changes like climate change and the loss of natural habitats, which are mainly due to anthropogenic influences. The coexistence of numerous species even in homogeneous environments is a stunning feature of natural communities and has been summarized under the term 'paradox of plankton'. Up to now, there are several mechanisms discussed, which may contribute to local and global diversity of organisms. Several interspecific trade offs have been identified maintaining the coexistence of species like their abilities regarding competition and predator avoidance, their capability to disperse in space and time, and their ability to exploit variable resources. Further, micro-evolutionary dynamics supporting the coexistence of species have been added to our knowledge, and deriving from theoretical deterministic models, non-linear dynamics which describe the temporal fluctuation of abundances of organisms. Whereas competition and predation seem to be clue structural elements within interacting organisms, the intrinsic dynamic behavior - by means of temporal changes in abundance - plays an important role regarding coexistence within a community. The present work sheds light on different factors affecting the coexistence of species using experimental microbial model systems consisting of a bacterivorous ciliate as the predator and two bacteria strains as prey organism. Additionally, another experimental setup consisting of two up to five bacteria species competing for one limiting resource was investigated. Highly controllable chemostat systems were established to exclude extrinsic disturbances. According to theoretical analyses I was able to show - experimentally and theoretically - that phenotypic plasticity of one species within a microbial one-predator-two-prey food web enlarges the range of possible coexistence of all species under different dynamic conditions, compared to a food web without phenotypic plasticity. This was accompanied by non-linear (chaotic) population dynamics within all experimental systems showing phenotypic plasticity. The experiments on the interplay of competition, predation and invasion showed that all aspects have an influence on species coexistence. Under undisturbed controlled conditions all aspects were analyzed in detail and in combination. Populations showed oscillations which were shown by quasi-chaotic attractors in phase space diagrams. Competition experiments with two up to five bacteria species competing for one limiting resource showed that all organisms were able to coexist which was mediated by species oscillations entering a regime of chaos. Besides that fact it was found, that the productivity (biomass) as well as the total cell numbers - under the same nutrition supply - increased by an increasing number of species in the experimental systems. Up to now, the occurrence of non-linear dynamics in well controlled experimental studies has been recognized several times and this phenomenon seemed to be more common in natural systems than generally assumed.}, language = {en} } @article{MuellerVeggianLiederBochevetal.1981, author = {M{\"u}ller-Veggian, Mattea and Lieder, R. M. and Bochev, B. and Kutsarova, T.}, title = {Study of a-induced non-equilibrium reactions with particle-y conincidences}, series = {Physica scripta. 24 (1981), H. 1-2}, journal = {Physica scripta. 24 (1981), H. 1-2}, isbn = {0031-8949}, pages = {123}, year = {1981}, language = {en} } @article{HillenUnglaubenMurdfield2001, author = {Hillen, Walter and Unglauben, F. and Murdfield, M.}, title = {Study of Database Connections for a Java Medical Image Viewer. Unglauben, F.; Hillen, W.; Murdfield, M.}, series = {Intelligente, innovative Produktentwicklung f{\"u}r die industrielle Praxis. Bl{\"u}mel, Bernd; Stenzel, Horst [Hrsg.]}, journal = {Intelligente, innovative Produktentwicklung f{\"u}r die industrielle Praxis. Bl{\"u}mel, Bernd; Stenzel, Horst [Hrsg.]}, publisher = {Forschungverbund Multimedia an Fachhochschulen}, address = {K{\"o}ln}, pages = {29 -- 33}, year = {2001}, language = {en} } @article{MuellerVeggianGonoLieder1976, author = {M{\"u}ller-Veggian, Mattea and Gono, Y. and Lieder, R. M.}, title = {Study of high spin states and isomers in ¹³⁵,¹³⁷ Ce}, series = {Annual report 1975 / Institut f{\"u}r Kernphysik Kernforschungsanlage J{\"u}lich / Ed. board: A. F{\"a}ßler ...}, journal = {Annual report 1975 / Institut f{\"u}r Kernphysik Kernforschungsanlage J{\"u}lich / Ed. board: A. F{\"a}ßler ...}, publisher = {Verlag des Forschungszentrums J{\"u}lich}, address = {J{\"u}lich}, pages = {51}, year = {1976}, language = {en} } @article{MuellerVeggianLiederGono1976, author = {M{\"u}ller-Veggian, Mattea and Lieder, R. M. and Gono, Y.}, title = {Study of high spin states in ¹⁹⁵,¹⁹⁷ Tl}, series = {Annual report 1975 / Institut f{\"u}r Kernphysik Kernforschungsanlage J{\"u}lich / Ed. board: A. F{\"a}ßler ...}, journal = {Annual report 1975 / Institut f{\"u}r Kernphysik Kernforschungsanlage J{\"u}lich / Ed. board: A. F{\"a}ßler ...}, publisher = {Verlag des Forschungszentrums J{\"u}lich}, address = {J{\"u}lich}, pages = {57}, year = {1976}, language = {en} } @article{MuellerVeggianLiederGono1975, author = {M{\"u}ller-Veggian, Mattea and Lieder, R. M. and Gono, Y.}, title = {Study of high spin states in ¹⁹⁵,¹⁹⁷ Tl}, series = {Annual report / Research Institute of Physics, AFI (1975)}, journal = {Annual report / Research Institute of Physics, AFI (1975)}, pages = {112}, year = {1975}, language = {en} } @article{MuellerVeggianGonoLiederetal.1976, author = {M{\"u}ller-Veggian, Mattea and Gono, Y. and Lieder, R. M. and Mayer-B{\"o}ricke, C.}, title = {Study of high spin states in ¹⁹⁵,¹⁹⁷ Tl}, series = {Fr{\"u}hjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft. 11 (1976)}, journal = {Fr{\"u}hjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft. 11 (1976)}, pages = {952}, year = {1976}, language = {en} } @article{OberlaenderJildehKirchneretal.2015, author = {Oberl{\"a}nder, Jan and Jildeh, Zaid B. and Kirchner, Patrick and Wendeler, Luisa and Bromm, Alexander and Iken, Heiko and Wagner, Patrick and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Study of Interdigitated Electrode Arrays Using Experiments and Finite Element Models for the Evaluation of Sterilization Processes}, series = {Sensors}, volume = {15}, journal = {Sensors}, number = {10}, publisher = {MDPI}, address = {Basel}, issn = {1424-8220}, doi = {10.3390/s151026115}, pages = {26115 -- 26127}, year = {2015}, abstract = {In this work, a sensor to evaluate sterilization processes with hydrogen peroxide vapor has been characterized. Experimental, analytical and numerical methods were applied to evaluate and study the sensor behavior. The sensor set-up is based on planar interdigitated electrodes. The interdigitated electrode structure consists of 614 electrode fingers spanning over a total sensing area of 20 mm2. Sensor measurements were conducted with and without microbiological spores as well as after an industrial sterilization protocol. The measurements were verified using an analytical expression based on a first-order elliptical integral. A model based on the finite element method with periodic boundary conditions in two dimensions was developed and utilized to validate the experimental findings.}, language = {en} } @article{MuellerVeggianKutsarovaBochevetal.1982, author = {M{\"u}ller-Veggian, Mattea and Kutsarova, T. and Bochev, B. and Lieder, R. M.}, title = {Study of non-equilibrium particle emission from the ¹⁵⁹ Tb (a, charged particle xn) reaction at Ea= 75 Mev}, series = {Annual report 1981 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: F. Gr{\"u}mmer. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 146)}, journal = {Annual report 1981 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: F. Gr{\"u}mmer. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 146)}, publisher = {Verlag des Forschungszentrums J{\"u}lich}, address = {J{\"u}lich}, pages = {37}, year = {1982}, language = {en} } @article{MuellerVeggianBeuscherBochevetal.1980, author = {M{\"u}ller-Veggian, Mattea and Beuscher, H. and Bochev, B. and Haenni, D. R.}, title = {Study of reactions ²⁰⁹ Bi (a,charged particle Xn) At Ea= 45 Mev and 75 Mev}, series = {Fr{\"u}hjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft (1980)}, journal = {Fr{\"u}hjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft (1980)}, pages = {1088}, year = {1980}, language = {en} } @inproceedings{MuellerVeggianNeskakisLiederetal.1978, author = {M{\"u}ller-Veggian, Mattea and Neskakis, A. and Lieder, R. M. and Beuscher, H.}, title = {Study of rotational aligned bands in ¹⁹⁰,¹⁹²,¹⁹⁴ Au}, series = {Nuclear interactions : International Conference on Nuclear Interactions held in Canberra, 28 Aug. - 1 Sept. 1978 / ed. by Brian Albert Robson. - (Lecture notes in physics ; 92)}, booktitle = {Nuclear interactions : International Conference on Nuclear Interactions held in Canberra, 28 Aug. - 1 Sept. 1978 / ed. by Brian Albert Robson. - (Lecture notes in physics ; 92)}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-540-09102-8}, pages = {428}, year = {1978}, language = {en} } @article{MuellerVeggianNeskakisLiederetal.1982, author = {M{\"u}ller-Veggian, Mattea and Neskakis, A. and Lieder, R. M. and Sletten, G.}, title = {Study of side-bands in ¹⁸⁰ Os}, series = {Annual report 1981 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: F. Gr{\"u}mmer. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 146)}, journal = {Annual report 1981 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: F. Gr{\"u}mmer. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 146)}, publisher = {Kernforschungsanlage}, address = {J{\"u}lich}, pages = {61}, year = {1982}, language = {en} } @article{MuellerVeggianDidelezLiederetal.1979, author = {M{\"u}ller-Veggian, Mattea and Didelez, J. P. and Lieder, R. M. and Beuscher, H.}, title = {Study of the exitation functions of ²¹¹,²¹² Po}, series = {Annual report 1978 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 36)}, journal = {Annual report 1978 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 36)}, publisher = {Kernforschungsanlage}, address = {J{\"u}lich}, pages = {37}, year = {1979}, language = {en} } @article{MuellerVeggianBeuscherHaenni1984, author = {M{\"u}ller-Veggian, Mattea and Beuscher, H. and Haenni, D. R.}, title = {Study of the level structure in ¹³⁴ Ce}, series = {Nuclear physics / A. 417 (1984), H. 2}, journal = {Nuclear physics / A. 417 (1984), H. 2}, isbn = {0375-9474}, pages = {189 -- 208}, year = {1984}, language = {en} } @article{MuellerVeggianKutsarovaBochevetal.1981, author = {M{\"u}ller-Veggian, Mattea and Kutsarova, T. and Bochev, B. and Didelez, J. P.}, title = {Study of the mechanism of the (a,dxn) and (a,txn) reactions at Ea= 45 Mev}, series = {Annual report 1980 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: F. Gr{\"u}mmer. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 99)}, journal = {Annual report 1980 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: F. Gr{\"u}mmer. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 99)}, publisher = {Kernforschungsanlage}, address = {J{\"u}lich}, pages = {58}, year = {1981}, language = {en} } @article{MuellerVeggianBochevLiederetal.1980, author = {M{\"u}ller-Veggian, Mattea and Bochev, B. and Lieder, R. M. and Didelez, J. P.}, title = {Study of ²⁰⁹ Bi (a,charged parzicle Xn) reactions}, series = {Annual report 1979 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 72)}, journal = {Annual report 1979 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 72)}, publisher = {Verlag des Forschungszentrums J{\"u}lich}, address = {J{\"u}lich}, pages = {33}, year = {1980}, language = {en} } @inproceedings{WeldenSeverinsPoghossianetal.2022, author = {Welden, Melanie and Severins, Robin and Poghossian, Arshak and Wege, Christina and Siegert, Petra and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Studying the immobilization of acetoin reductase with Tobacco mosaic virus particles on capacitive field-effect sensors}, series = {2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)}, booktitle = {2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN)}, publisher = {IEEE}, isbn = {978-1-6654-5860-3 (Online)}, doi = {10.1109/ISOEN54820.2022.9789657}, pages = {4 Seiten}, year = {2022}, abstract = {A capacitive electrolyte-insulator-semiconductor (EISCAP) biosensor modified with Tobacco mosaic virus (TMV) particles for the detection of acetoin is presented. The enzyme acetoin reductase (AR) was immobilized on the surface of the EISCAP using TMV particles as nanoscaffolds. The study focused on the optimization of the TMV-assisted AR immobilization on the Ta 2 O 5 -gate EISCAP surface. The TMV-assisted acetoin EISCAPs were electrochemically characterized by means of leakage-current, capacitance-voltage, and constant-capacitance measurements. The TMV-modified transducer surface was studied via scanning electron microscopy.}, language = {en} } @article{BegingLeinhosJablonskietal.2015, author = {Beging, Stefan and Leinhos, Marcel and Jablonski, Melanie and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Studying the spatially resolved immobilisation of enzymes on a capacitive field-effect structure by means of nano-spotting}, series = {Physica status solidi (a)}, volume = {212}, journal = {Physica status solidi (a)}, number = {6}, publisher = {Wiley}, address = {Weinheim}, issn = {1862-6319}, doi = {10.1002/pssa.201431891}, pages = {1353 -- 1358}, year = {2015}, language = {en} } @article{ArreolaOberlaenderMaetzkowetal.2017, author = {Arreola, Julio and Oberl{\"a}nder, Jan and M{\"a}tzkow, M. and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Surface functionalization for spore-based biosensors with organosilanes}, series = {Electrochimica Acta}, volume = {241}, journal = {Electrochimica Acta}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0013-4686}, doi = {10.1016/j.electacta.2017.04.157}, pages = {237 -- 243}, year = {2017}, abstract = {In the present work, surface functionalization of different sensor materials was studied. Organosilanes are well known to serve as coupling agent for biomolecules or cells on inorganic materials. 3-aminopropyltriethoxysilane (APTES) was used to attach microbiological spores time to an interdigitated sensor surface. The functionality and physical properties of APTES were studied on isolated sensor materials, namely silicon dioxide (SiO2) and platinum (Pt) as well as the combined material on sensor level. A predominant immobilization of spores could be demonstrated on SiO2 surfaces. Additionally, the impedance signal of APTES-functionalized biosensor chips has been investigated.}, language = {en} } @article{BronderPoghossianJessingetal.2019, author = {Bronder, Thomas and Poghossian, Arshak and Jessing, Max P. and Keusgen, Michael and Sch{\"o}ning, Michael Josef}, title = {Surface regeneration and reusability of label-free DNA biosensors based on weak polyelectrolyte-modified capacitive field-effect structures}, series = {Biosensors and Bioelectronics}, volume = {126}, journal = {Biosensors and Bioelectronics}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0956-5663}, doi = {10.1016/j.bios.2018.11.019}, pages = {510 -- 517}, year = {2019}, language = {en} } @article{HamouKotliarTanetal.2020, author = {Hamou, Hussam Aldin and Kotliar, Konstantin and Tan, Sonny Kian and Weiß, Christel and Blume, Christian and Clusmann, Hans and Schubert, Gerrit Alexander and Albanna, Walid}, title = {Surgical nuances and placement of subgaleal drains for supratentorial procedures—a prospective analysis of efficacy and outcome in 150 craniotomies}, series = {Acta Neurochirurgica}, volume = {2020}, journal = {Acta Neurochirurgica}, number = {162}, publisher = {Springer Nature}, address = {Cham}, issn = {0942-0940}, doi = {10.1007/s00701-019-04196-6}, pages = {729 -- 736}, year = {2020}, abstract = {Background For supratentorial craniotomy, surgical access, and closure technique, including placement of subgaleal drains, may vary considerably. The influence of surgical nuances on postoperative complications such as cerebrospinal fluid leakage or impaired wound healing overall remains largely unclear. With this study, we are reporting our experiences and the impact of our clinical routines on outcome in a prospectively collected data set. Method We prospectively observed 150 consecutive patients undergoing supratentorial craniotomy and recorded technical variables (type/length of incision, size of craniotomy, technique of dural and skin closure, type of dressing, and placement of subgaleal drains). Outcome variables (subgaleal hematoma/CSF collection, periorbital edema, impairment of wound healing, infection, and need for operative revision) were recorded at time of discharge and at late follow-up. Results Early subgaleal fluid collection was observed in 36.7\% (2.8\% at the late follow-up), and impaired wound healing was recorded in 3.3\% of all cases, with an overall need for operative revision of 6.7\%. Neither usage of dural sealants, lack of watertight dural closure, and presence of subgaleal drains, nor type of skin closure or dressing influenced outcome. Curved incisions, larger craniotomy, and tumor size, however, were associated with an increase in early CSF or hematoma collection (p < 0.0001, p = 0.001, p < 0.01 resp.), and larger craniotomy size was associated with longer persistence of subgaleal fluid collections (p < 0.05). Conclusions Based on our setting, individual surgical nuances such as the type of dural closure and the use of subgaleal drains resulted in a comparable complication rate and outcome. Subgaleal fluid collections were frequently observed after supratentorial procedures, irrespective of the closing technique employed, and resolve spontaneously in the majority of cases without significant sequelae. Our results are limited due to the observational nature in our single-center study and need to be validated by supportive prospective randomized design.}, language = {en} } @article{BalakirskiKotliarPaulyetal.2018, author = {Balakirski, Galina and Kotliar, Konstantin and Pauly, Karolin J. and Krings, Laura K. and R{\"u}bben, Albert and Baron, Jens M. and Schmitt, Laurenz}, title = {Surgical Site Infections After Dermatologic Surgery in Immunocompromised Patients: A Single-Center Experience}, series = {Dermatologic Surgery}, journal = {Dermatologic Surgery}, number = {44 (12)}, publisher = {Wolters Kluwer}, doi = {10.1097/DSS.0000000000001615}, pages = {1525 -- 1536}, year = {2018}, abstract = {BACKGROUND Immunosuppression is often considered as an indication for antibiotic prophylaxis to prevent surgical site infections (SSI) while performing skin surgery. However, the data on the risk of developing SSI after dermatologic surgery in immunosuppressed patients are limited. PATIENTS AND METHODS All patients of the Department of Dermatology and Allergology at the University Hospital of RWTH Aachen in Aachen, Germany, who underwent hospitalization for a dermatologic surgery between June 2016 and January 2017 (6 months), were followed up after surgery until completion of the wound healing process. The follow-up addressed the occurrence of SSI and the need for systemic antibiotics after the operative procedure. Immunocompromised patients were compared with immunocompetent patients. The investigation was conducted as a retrospective analysis of patient records. RESULTS The authors performed 284 dermatologic surgeries in 177 patients. Nineteen percent (54/284) of the skin surgery was performed on immunocompromised patients. The most common indications for surgical treatment were nonmelanoma skin cancer and malignant melanomas. Surgical site infections occurred in 6.7\% (19/284) of the cases. In 95\% (18/19), systemic antibiotic treatment was needed. Twenty-one percent of all SSI (4/19) were seen in immunosuppressed patients. CONCLUSION According to the authors' data, immunosuppression does not represent a significant risk factor for SSI after dermatologic surgery. However, larger prospective studies are needed to make specific recommendations on the use of antibiotic prophylaxis while performing skin surgery in these patients. The available data on complications after dermatologic surgery have improved over the past years. Particularly, additional risk factors have been identified for surgical site infections (SSI). Purulent surgical sites, older age, involvement of head, neck, and acral regions, and also the involvement of less experienced surgeons have been reported to increase the risk of the SSI after dermatologic surgeries.1 In general, the incidence of SSI after skin surgery is considered to be low.1,2 However, antibiotics in dermatologic surgeries, especially in the perioperative setting, seem to be overused,3,4 particularly regarding developing antibiotic resistances and side effects. Immunosuppression has been recommended to be taken into consideration as an additional indication for antibiotic prophylaxis to prevent SSI after skin surgery in special cases.5,6 However, these recommendations do not specify the exact dermatologic surgeries, and were not specifically developed for dermatologic surgery patients and treatments, but adopted from other surgical fields.6 According to the survey conducted on American College of Mohs Surgery members in 2012, 13\% to 29\% of the surgeons administered antibiotic prophylaxis to immunocompromised patients to prevent SSI while performing dermatologic surgery on noninfected skin,3 although this was not recommended by Journal of the American Academy of Dermatology Advisory Statement. Indeed, the data on the risk of developing SSI after dermatologic surgery in immunosuppressed patients are limited. However, it is possible that due to the insufficient evidence on the risk of SSI occurrence in this patient group, dermatologic surgeons tend to overuse perioperative antibiotic prophylaxis. To make specific recommendations on the use of antibiotic prophylaxis in immunosuppressed patients in the field of skin surgery, more information about the incidence of SSI after dermatologic surgery in these patients is needed. The aim of this study was to fill this data gap by investigating whether there is an increased risk of SSI after skin surgery in immunocompromised patients compared with immunocompetent patients.}, language = {en} } @article{BhattaraiJabbariAndingetal.2018, author = {Bhattarai, Aroj and Jabbari, Medisa and Anding, Ralf and Staat, Manfred}, title = {Surgical treatment of vaginal vault prolapse using different prosthetic mesh implants: a finite element analysis}, series = {tm - Technisches Messen}, volume = {85}, journal = {tm - Technisches Messen}, number = {5}, publisher = {De Gruyter}, address = {Berlin}, issn = {2196-7113}, doi = {10.1515/teme-2017-0115}, pages = {331 -- 342}, year = {2018}, abstract = {Particularly multiparous elderly women may suffer from vaginal vault prolapse after hysterectomy due to weak support from lax apical ligaments. A decreased amount of estrogen and progesterone in older age is assumed to remodel the collagen thereby reducing tissue stiffness. Sacrocolpopexy is either performed as open or laparoscopic surgery using prosthetic mesh implants to substitute lax ligaments. Y-shaped mesh models (DynaMesh, Gynemesh, and Ultrapro) are implanted in a 3D female pelvic floor finite element model in the extraperitoneal space from the vaginal cuff to the first sacral (S1) bone below promontory. Numerical simulations are conducted during Valsalva maneuver with weakened tissues modeled by reduced tissue stiffness. Tissues are modeled as incompressible, isotropic hyperelastic materials whereas the meshes are modeled either as orthotropic linear elastic or as isotropic hyperlastic materials. The positions of the vaginal cuff and the bladder base are calculated from the pubococcygeal line for female pelvic floor at rest, for prolapse and after repair using the three meshes. Due to mesh mechanics and mesh pore deformation along the loaded direction, the DynaMesh with regular rectangular mesh pores is found to provide better mechanical support to the organs than the Gynemesh and the Ultrapro with irregular hexagonal mesh pores. Insbesondere {\"a}ltere, mehrgeb{\"a}hrende Frauen leiden h{\"a}ufiger an einem Scheidenvorfall nach einer Hysterektomie aufgrund der schwachen Unterst{\"u}tzung durch laxe apikale B{\"a}nder. Es wird angenommen, dass eine verringerte Menge an {\"O}strogen und Progesteron im h{\"o}heren Alter das Kollagen umformt, wodurch die Gewebesteifigkeit reduziert wird. Die Sakrokolpopexie ist eine offene oder laparoskopische Operation, die mit prothetischen Netzimplantaten durchgef{\"u}hrt wird, um laxe B{\"a}nder zu ersetzen. Y-f{\"o}rmige Netzmodelle (DynaMesh, Gynemesh und Ultrapro) werden in einem 3D-Modell des weiblichen Beckenbodens im extraperitonealen Raum vom Vaginalstumpf bis zum Promontorium implantiert. Numerische Simulationen werden w{\"a}hrend des Valsalva-Man{\"o}vers mit geschw{\"a}chtem Gewebe durchgef{\"u}hrt, das durch eine reduzierte Gewebesteifigkeit modelliert wird. Die Gewebe werden als inkompressible, isotrop hyperelastische Materialien modelliert, w{\"a}hrend die Netze entweder als orthotrope linear elastische oder als isotrope hyperlastische Materialien modelliert werden. Die Positionen des Vaginalstumpfs, der Blase und der Harnr{\"o}hrenachse werden anhand der Pubococcygeallinie aus der Ruhelage, f{\"u}r den Prolaps und nach der Reparatur unter Verwendung der drei Netze berechnet. Aufgrund der Netzmechanik und der Netzporenverformung bietet das DynaMesh mit regelm{\"a}ßigen rechteckigen Netzporen eine bessere mechanische Unterst{\"u}tzung und eine Neupositionierung des Scheidengew{\"o}lbes, der Blase und der Urethraachse als Gynemesh und Ultrapro mit unregelm{\"a}ßigen hexagonalen Netzporen.}, language = {en} } @article{DigelWehlitzKayseretal.2018, author = {Digel, Ilya and Wehlitz, V. and Kayser, Peter and Figiel-Lange, A. and Bassam, R. and Rundstedt, F. von}, title = {Suspension depletion approach for exemption of infected Solanum jasminoides cells from pospiviroids}, series = {Plant Pathology}, volume = {67}, journal = {Plant Pathology}, number = {2}, publisher = {Wiley}, address = {Oxford}, issn = {1365-3059}, doi = {10.1111/ppa.12750}, pages = {358 -- 365}, year = {2018}, abstract = {Despite numerous studies, viroid elimination from infected plants remains a very challenging task. This study introduces for the first time a novel 'suspension depletion' approach for exemption of Solanum jasminoides plants from viroids. The proposed method implies initial establishment of suspension cultures of the infected plant cells. The suspended cells were then physically treated (mild thermotherapy, 33 °C), which presumably delayed the replication of the viroid. The viroid concentration in the treated biomass was monitored weekly using pospiviroid-specific PCR. After 10-12 weeks of continuous treatment, a sufficient decrease in viroid concentration was observed such that the infection became undetectable by PCR. The treated single cells then gave rise to microcolonies on a solid culture medium and the obtained viroid-negative clones were further promoted to regenerate into viroid-free plants. Three years of accumulated experimental data suggests feasibility, broad applicability, and good efficacy of the proposed approach.}, language = {en} } @article{HacklAndermahrStaatetal.2017, author = {Hackl, M. and Andermahr, J. and Staat, Manfred and Bremer, I. and Borggrefe, J. and Prescher, A. and M{\"u}ller, L. P. and Wegmann, K.}, title = {Suture button reconstruction of the central band of the interosseous membrane in Essex-Lopresti lesions: a comparative biomechanical investigation}, series = {The Journal of Hand Surgery (European Volume)}, volume = {42}, journal = {The Journal of Hand Surgery (European Volume)}, number = {4}, publisher = {Sage}, address = {London}, issn = {2043-6289 (Online)}, doi = {10.1177/1753193416665943}, pages = {370 -- 376}, year = {2017}, language = {en} } @article{KodomskoiKotliarSchroederetal.2019, author = {Kodomskoi, Leonid and Kotliar, Konstantin and Schr{\"o}der, Andreas and Weiss, Michael and Hille, Konrad}, title = {Suture-Probe Canaloplasty as an Alternative to Canaloplasty using the iTrack™ Microcatheter}, series = {Journal of Glaucoma}, journal = {Journal of Glaucoma}, number = {Epub ahead of print}, publisher = {Lippincott Williams \& Wilkins}, address = {Philadelphia}, issn = {1057-0829}, doi = {10.1097/IJG.0000000000001321}, year = {2019}, language = {en} } @book{GrotendorstDornseifferSchoberth1994, author = {Grotendorst, Johannes and Dornseiffer, J{\"u}rgen and Schoberth, Siegfried M.}, title = {Symbolic-numeric computation techniques for problem-solving in Physical Chemistry and Biochemistry . Stand 08.06.1994 / Grotendorst, Johannes ; Dornseiffer, J{\"u}rgen ; Schoberth, Siegfried M.}, publisher = {ZAM, KFA}, address = {J{\"u}lich}, pages = {9 S.}, year = {1994}, language = {en} } @book{GrotendorstDornseifferSchoberth1994, author = {Grotendorst, Johannes and Dornseiffer, J{\"u}rgen and Schoberth, Siegfried M.}, title = {Symbolic-numeric computation techniques for problem-solving in Physical Chemistry and Biochemistry . Stand 08.06.1994 / Grotendorst, Johannes ; Dornseiffer, J{\"u}rgen ; Schoberth, Siegfried M.}, publisher = {ZAM, KFA}, address = {J{\"u}lich}, pages = {9 S.}, year = {1994}, language = {en} } @book{StaatErni2019, author = {Staat, Manfred and Erni, Daniel}, title = {Symposium Proceedings; 3rd YRA MedTech Symposium 2019: May 24 / 2019 / FH Aachen}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-22-6}, doi = {10.17185/duepublico/48750}, pages = {49 Seiten}, year = {2019}, language = {en} } @book{StaatDigelTrzewiketal.2024, author = {Staat, Manfred and Digel, Ilya and Trzewik, J{\"u}rgen and Sielemann, Stefanie and Erni, Daniel and Zylka, Waldemar}, title = {Symposium Proceedings; 4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen}, publisher = {Universit{\"a}t Duisburg-Essen}, address = {Duisburg}, organization = {MedTech Symposium}, isbn = {978-3-940402-65-3}, doi = {10.17185/duepublico/81475}, pages = {40 Seiten}, year = {2024}, language = {en} } @article{LehnertzBialonskiHorstmannetal.2009, author = {Lehnertz, Klaus and Bialonski, Stephan and Horstmann, Marie-Therese and Krug, Dieter and Rothkegel, Alexander and Staniek, Matth{\"a}us and Wagner, Tobias}, title = {Synchronization phenomena in human epileptic brain networks}, series = {Journal of neuroscience methods}, volume = {183}, journal = {Journal of neuroscience methods}, number = {1}, issn = {0165-0270}, doi = {10.1016/j.jneumeth.2009.05.015}, pages = {42 -- 48}, year = {2009}, language = {en} } @article{MuschallikMolinnusJablonskietal.2020, author = {Muschallik, Lukas and Molinnus, Denise and Jablonski, Melanie and Kipp, Carina Ronja and Bongaerts, Johannes and Pohl, Martina and Wagner, Torsten and Sch{\"o}ning, Michael Josef and Selmer, Thorsten and Siegert, Petra}, title = {Synthesis of α-hydroxy ketones and vicinal (R, R)-diols by Bacillus clausii DSM 8716ᵀ butanediol dehydrogenase}, series = {RSC Advances}, volume = {10}, journal = {RSC Advances}, publisher = {Royal Society of Chemistry (RSC)}, address = {Cambridge}, issn = {2046-2069}, doi = {10.1039/D0RA02066D}, pages = {12206 -- 12216}, year = {2020}, abstract = {α-hydroxy ketones (HK) and 1,2-diols are important building blocks for fine chemical synthesis. Here, we describe the R-selective 2,3-butanediol dehydrogenase from B. clausii DSM 8716ᵀ (BcBDH) that belongs to the metal-dependent medium chain dehydrogenases/reductases family (MDR) and catalyzes the selective asymmetric reduction of prochiral 1,2-diketones to the corresponding HK and, in some cases, the reduction of the same to the corresponding 1,2-diols. Aliphatic diketones, like 2,3-pentanedione, 2,3-hexanedione, 5-methyl-2,3-hexanedione, 3,4-hexanedione and 2,3-heptanedione are well transformed. In addition, surprisingly alkyl phenyl dicarbonyls, like 2-hydroxy-1-phenylpropan-1-one and phenylglyoxal are accepted, whereas their derivatives with two phenyl groups are not substrates. Supplementation of Mn²⁺ (1 mM) increases BcBDH's activity in biotransformations. Furthermore, the biocatalytic reduction of 5-methyl-2,3-hexanedione to mainly 5-methyl-3-hydroxy-2-hexanone with only small amounts of 5-methyl-2-hydroxy-3-hexanone within an enzyme membrane reactor is demonstrated.}, language = {en} } @article{MuschallikKippReckeretal.2020, author = {Muschallik, Lukas and Kipp, Carina Ronja and Recker, Inga and Bongaerts, Johannes and Pohl, Martina and Gelissen, Melanie and Sch{\"o}ning, Michael Josef and Selmer, Thorsten and Siegert, Petra}, title = {Synthesis of α-hydroxy ketones and vicinal diols with the Bacillus licheniformis DSM 13T butane-2, 3-diol dehydrogenase}, series = {Journal of Biotechnology}, volume = {202}, journal = {Journal of Biotechnology}, number = {Vol. 324}, publisher = {Elsevier}, address = {Amsterdam}, isbn = {2590-1559}, doi = {10.1016/j.jbiotec.2020.09.016}, pages = {61 -- 70}, year = {2020}, abstract = {The enantioselective synthesis of α-hydroxy ketones and vicinal diols is an intriguing field because of the broad applicability of these molecules. Although, butandiol dehydrogenases are known to play a key role in the production of 2,3-butandiol, their potential as biocatalysts is still not well studied. Here, we investigate the biocatalytic properties of the meso-butanediol dehydrogenase from Bacillus licheniformis DSM 13T (BlBDH). The encoding gene was cloned with an N-terminal StrepII-tag and recombinantly overexpressed in E. coli. BlBDH is highly active towards several non-physiological diketones and α-hydroxyketones with varying aliphatic chain lengths or even containing phenyl moieties. By adjusting the reaction parameters in biotransformations the formation of either the α-hydroxyketone intermediate or the diol can be controlled.}, language = {en} } @article{TurlybekulyPogrebnjakSukhodubetal.2019, author = {Turlybekuly, Amanzhol and Pogrebnjak, Alexander and Sukhodub, L. F. and Sukhodub, Liudmyla B. and Kistaubayeva, A. S. and Savitskaya, Irina and Shokatayeva, D. H. and Bondar, Oleksandr V. and Shaimardanov, Z. K. and Plotnikov, Sergey V. and Shaimardanova, B. H. and Digel, Ilya}, title = {Synthesis, characterization, in vitro biocompatibility and antibacterial properties study of nanocomposite materials based on hydroxyapatite-biphasic ZnO micro- and nanoparticles embedded in Alginate matrix}, series = {Materials Science and Engineering C}, volume = {104}, journal = {Materials Science and Engineering C}, number = {Article number 109965}, publisher = {Elsevier}, address = {Amsterdam}, doi = {10.1016/j.msec.2019.109965}, year = {2019}, language = {en} }