@article{KobusBitzUdenetal.2012,
  author    = {Kobus, Thiele and Bitz, Andreas and Uden, Mark J. van and Lagemaat, Miram W. and Rothgang, Eva and Orzada, Stephan and Heerschap, Arend and Scheenen, Tom W. J.},
  title     = {In vivo 31P MR spectroscopic imaging of the human prostate at 7 T: safety and feasibility},
  series = {Magnetic Resonance in Medicine},
  volume    = {68},
  journal   = {Magnetic Resonance in Medicine},
  number    = {6},
  publisher = {Wiley-Liss},
  address   = {New York},
  issn      = {1522-2594},
  doi       = {10.1002/mrm.24175},
  pages     = {1683 -- 1695},
  year      = {2012},
  abstract  = {31P MR spectroscopic imaging of the human prostate provides information about phosphorylated metabolites that could be used for prostate cancer characterization. The sensitivity of a magnetic field strength of 7 T might enable 3D 31P MR spectroscopic imaging with relevant spatial resolution in a clinically acceptable measurement time. To this end, a 31P endorectal coil was developed and combined with an eight-channel 1H body-array coil to relate metabolic information to anatomical location. An extensive safety validation was performed to evaluate the specific absorption rate, the radiofrequency field distribution, and the temperature distribution of both coils. This validation consisted of detailed Finite Integration Technique simulations, confirmed by MR thermometry and Burn:x-wiley:07403194:media:MRM24175:tex2gif-stack-1 measurements in a phantom and in vivo temperature measurements. The safety studies demonstrated that the presence of the 31P endorectal coil had no influence on the specific absorption rate levels and temperature distribution of the external eight-channel 1H array coil. To stay within a 10 g averaged local specific absorption rate of 10 W/kg, a maximum time-averaged input power of 33 W for the 1H array coil was allowed. For transmitting with the 31P endorectal coil, our safety limit of less than 1°C temperature increase in vivo during a 15-min MR spectroscopic imaging experiment was reached at a time-averaged input power of 1.9 W. With this power setting, a second in vivo measurement was performed on a healthy volunteer. Using adiabatic excitation, 3D 31P MR spectroscopic imaging produced spectra from the entire prostate in 18 min with a spatial resolution of 4 cm3. The spectral resolution enabled the separate detection of phosphocholine, phosphoethanolamine, inorganic phosphate, and other metabolites that could play an important role in the characterization of prostate cancer.},
  language  = {en}
}
@phdthesis{Kotliar2012,
  author    = {Kotliar, Konstantin},
  title     = {Pathophysiologische Beurteilung und h{\"a}modynamische Analyse von mikrostrukturellen Ver{\"a}nderungen des retinalen Gef{\"a}ßl{\"a}ngsschnittsprofils},
  pages     = {328 S.},
  year      = {2012},
  language  = {ru}
}
@article{KotliarLanzlHanssenetal.2012,
  author    = {Kotliar, Konstantin and Lanzl, Ines M. and Hanssen, Henner and Eberhardt, Karla and Vilser, Walthard and Halle, Martin and Heemann, Uwe and Schmidt-Trucks{\"a}ss, Arno and Baumann, Marcus},
  title     = {Does increased blood pressure rather than aging influence retinal pulse wave velocity?},
  series = {Investigative Ophthalmology \& Visual Science, IOVS},
  volume    = {53},
  journal   = {Investigative Ophthalmology \& Visual Science, IOVS},
  number    = {4},
  publisher = {ARVO},
  address   = {Rockville, Md.},
  issn      = {0146-0404},
  doi       = {10.1167/iovs.11-8815},
  pages     = {2119 -- 2126},
  year      = {2012},
  abstract  = {Purpose: It was demonstrated previously that retinal pulse wave velocity (rPWV) as a measure of retinal arterial stiffness is increased in aged anamnestically healthy volunteers compared with young healthy subjects. Using novel methodology of rPWV assessment this finding was confirmed and investigated whether it might relate to the increased blood pressure usually accompanying the aging process, rather than to the aging itself. Methods: A total of 12 young 25.5-year-old (24.0-28.8) [median(1st quartile-3rd quartile)] and 12 senior 68.5-year-old (63.8-71.8) anamnestically healthy volunteers; and 12 senior 63.0-year-old (60.8-65.0) validated healthy volunteers and 12 young 33.0-year-old (29.5-35.0) hypertensive patients were examined. Time-dependent alterations of vessel diameter were assessed by the Dynamic Vessel Analyzer in a retinal artery of each subject. The data were filtered and processed using mathematical signal analysis and rPWVs were calculated. Results: rPWV amounted to 1200 (990-1470) RU (relative units)/s in the hypertensive group and to 1040 (700-2230) RU/s in anamnestically healthy seniors. These differed significantly from rPWVs in young healthy group (410 [280-500] RU/s) and in validated healthy seniors (400 [320-510] RU/s). rPWV associated with age and mean arterial pressure (MAP) in the pooled cohort excluded validated healthy seniors. In a regression model these associations remain when alternately adjusted for MAP and age. When including validated healthy seniors in the pooled cohort only association with MAP remains. Conclusions: Both aging (with not excluded cardiovascular risk factors) and mild hypertension are associated with elevated rPWV. rPWV increases to a similar extent both in young mildly hypertensive subjects and in aged anamnestically healthy persons. Healthy aging is not associated with increased rPWV.},
  language  = {en}
}
@article{KrollLudwigs2012,
  author    = {Kroll-Ludwigs, Kathrin},
  title     = {Ein optionales Vertragsrecht f{\"u}r Europa: Motor oder Hemmnis f{\"u}r den Binnenmarkt?},
  series = {GPR : Zeitschrift f{\"u}r Gemeinschaftsprivatrecht},
  volume    = {9},
  journal   = {GPR : Zeitschrift f{\"u}r Gemeinschaftsprivatrecht},
  number    = {4},
  publisher = {Verlag Dr. Otto Schmidt},
  address   = {K{\"o}ln},
  issn      = {2193-9519},
  doi       = {10.1515/gpr.2012.9.4.181},
  pages     = {181 -- 188},
  year      = {2012},
  language  = {de}
}
@incollection{KuhlmannButenwegMeskourisetal.2012,
  author    = {Kuhlmann, Wolfram and Butenweg, Christoph and Meskouris, Konstantin and Kempen, Thomas},
  title     = {Simulation des Tragverhaltens des Aachener Doms im Erdbebenfall},
  series = {Die karolingische Pfalzkapelle in Aachen : Material, Bautechnik, Restaurierung. (Arbeitshefte der rheinischen Denkmalpflege ; 78)},
  booktitle = {Die karolingische Pfalzkapelle in Aachen : Material, Bautechnik, Restaurierung. (Arbeitshefte der rheinischen Denkmalpflege ; 78)},
  publisher = {Wernersche Verlags-Gesellschaft},
  address   = {Worms},
  isbn      = {978-3-88462-325-1},
  pages     = {237 -- 248},
  year      = {2012},
  language  = {de}
}
@inproceedings{KuhnhenneDoeringPyschnyetal.2012,
  author    = {Kuhnhenne, Markus and D{\"o}ring, Bernd and Pyschny, Dominik and Feldmann, Markus},
  title     = {Energy efficient sandwich construction},
  series = {Proceedings of the VI International Congress on Architectural Envelopes : 20.6. - 22.6.2012, San Sebastian, Spain},
  booktitle = {Proceedings of the VI International Congress on Architectural Envelopes : 20.6. - 22.6.2012, San Sebastian, Spain},
  publisher = {ICAE},
  organization    = {International Congress on Architectural Envelopes <6, 2012, San Sebastian>},
  pages     = {277 -- 285},
  year      = {2012},
  language  = {en}
}
@phdthesis{KurulganDemirci2012,
  author    = {Kurulgan Demirci, Eylem},
  title     = {The effect of rhAPC on contractile tension : an in-vitro sepsis model of cardiomyocytes and endothelial cells},
  year      = {2012},
  language  = {en}
}
@article{KurulganDemirciDemirciLinderetal.2012,
  author    = {Kurulgan Demirci, Eylem and Demirci, Taylan and Linder, Peter and Trzewik, J{\"u}rgen and Gierkowski, Jessica Ricarda and Gossmann, Matthias and Kayser, Peter and Porst, Dariusz and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {rhAPC reduces the endothelial cell permeability via a decrease of contractile tensions induced by endothelial cells},
  series = {Journal of Bioscience and Bioengineering},
  volume    = {113},
  journal   = {Journal of Bioscience and Bioengineering},
  number    = {2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1347-4421},
  doi       = {10.1016/j.jbiosc.2012.03.019},
  pages     = {212 -- 219},
  year      = {2012},
  abstract  = {All cells generate contractile tension. This strain is crucial for mechanically controlling the cell shape, function and survival. In this study, the CellDrum technology quantifying cell's (the cellular) mechanical tension on a pico-scale was used to investigate the effect of lipopolysaccharide (LPS) on human aortic endothelial cell (HAoEC) tension. The LPS effect during gram-negative sepsis on endothelial cells is cell contraction causing endothelium permeability increase. The aim was to finding out whether recombinant activated protein C (rhAPC) would reverse the endothelial cell response in an in-vitro sepsis model. In this study, the established in-vitro sepsis model was confirmed by interleukin 6 (IL-6) levels at the proteomic and genomic levels by ELISA, real time-PCR and reactive oxygen species (ROS) activation by florescence staining. The thrombin cellular contraction effect on endothelial cells was used as a positive control when the CellDrum technology was applied. Additionally, the Ras homolog gene family, member A (RhoA) mRNA expression level was checked by real time-PCR to support contractile tension results. According to contractile tension results, the mechanical predominance of actin stress fibers was a reason of the increased endothelial contractile tension leading to enhanced endothelium contractility and thus permeability enhancement. The originality of this data supports firstly the basic measurement principles of the CellDrum technology and secondly that rhAPC has a beneficial effect on sepsis influenced cellular tension. The technology presented here is promising for future high-throughput cellular tension analysis that will help identify pathological contractile tension responses of cells and prove further cell in-vitro models.},
  language  = {en}
}
@incollection{Kurz2012,
  author    = {Kurz, Melanie},
  title     = {Prizing \& Pricing : Design zwischen Rang und Regal},
  series = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  booktitle = {Vielen Dank f{\"u}r Ihren Einkauf : Konsumkultur aus Sicht von Design, Kunst und Medien},
  publisher = {Transcript Verlag},
  address   = {Bielefeld},
  isbn      = {978-3-8376-2170-9},
  doi       = {10.1515/transcript.9783839421703.26},
  pages     = {26 -- 39},
  year      = {2012},
  language  = {de}
}
@inproceedings{KoetterDeckerDetzleretal.2012,
  author    = {K{\"o}tter, Jens and Decker, Stefan and Detzler, Raphael and Sch{\"a}fer, Jochen and Schmitz, Mark and Herrmann, Ulf},
  title     = {Cost Reduction of Solar Fields with HelioTrough Collector},
  publisher = {FLAGSOL},
  address   = {K{\"o}ln},
  pages     = {9 S. : Ill., graph. Darst.},
  year      = {2012},
  language  = {en}
}