@article{CiritsisHorbachStaatetal.2018, author = {Ciritsis, Alexander and Horbach, Andreas and Staat, Manfred and Kuhl, Christiane K. and Kraemer, Nils Andreas}, title = {Porosity and tissue integration of elastic mesh implants evaluated in vitro and in vivo}, series = {Journal of Biomedical Materials Research: Part B: Applied Biomaterials}, volume = {106}, journal = {Journal of Biomedical Materials Research: Part B: Applied Biomaterials}, number = {2}, publisher = {Wiley}, address = {New York, NY}, issn = {1552-4981}, doi = {10.1002/jbm.b.33877}, pages = {827 -- 833}, year = {2018}, abstract = {Purpose In vivo, a loss of mesh porosity triggers scar tissue formation and restricts functionality. The purpose of this study was to evaluate the properties and configuration changes as mesh deformation and mesh shrinkage of a soft mesh implant compared with a conventional stiff mesh implant in vitro and in a porcine model. Material and Methods Tensile tests and digital image correlation were used to determine the textile porosity for both mesh types in vitro. A group of three pigs each were treated with magnetic resonance imaging (MRI) visible conventional stiff polyvinylidene fluoride meshes (PVDF) or with soft thermoplastic polyurethane meshes (TPU) (FEG Textiltechnik mbH, Aachen, Germany), respectively. MRI was performed with a pneumoperitoneum at a pressure of 0 and 15 mmHg, which resulted in bulging of the abdomen. The mesh-induced signal voids were semiautomatically segmented and the mesh areas were determined. With the deformations assessed in both mesh types at both pressure conditions, the porosity change of the meshes after 8 weeks of ingrowth was calculated as an indicator of preserved elastic properties. The explanted specimens were examined histologically for the maturity of the scar (collagen I/III ratio). Results In TPU, the in vitro porosity increased constantly, in PVDF, a loss of porosity was observed under mild stresses. In vivo, the mean mesh areas of TPU were 206.8 cm2 (± 5.7 cm2) at 0 mmHg pneumoperitoneum and 274.6 cm2 (± 5.2 cm2) at 15 mmHg; for PVDF the mean areas were 205.5 cm2 (± 8.8 cm2) and 221.5 cm2 (± 11.8 cm2), respectively. The pneumoperitoneum-induced pressure increase resulted in a calculated porosity increase of 8.4\% for TPU and of 1.2\% for PVDF. The mean collagen I/III ratio was 8.7 (± 0.5) for TPU and 4.7 (± 0.7) for PVDF. Conclusion The elastic properties of TPU mesh implants result in improved tissue integration compared to conventional PVDF meshes, and they adapt more efficiently to the abdominal wall. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 827-833, 2018.}, language = {en} } @article{LanzlKotliar2017, author = {Lanzl, I. and Kotliar, Konstantin}, title = {K{\"o}nnen Anti-VEGF-Injektionen Glaukom oder okul{\"a}re Hypertension verursachen?}, series = {Klinische Monatsbl{\"a}tter f{\"u}r Augenheilkunde}, volume = {234}, journal = {Klinische Monatsbl{\"a}tter f{\"u}r Augenheilkunde}, number = {2}, publisher = {Thieme}, address = {Stuttgart}, issn = {0023-2165}, doi = {10.1055/s-0043-101819}, pages = {191 -- 193}, year = {2017}, language = {de} } @article{ZangeSchopenAlbrachtetal.2017, author = {Zange, Jochen and Schopen, Kathrin and Albracht, Kirsten and Gerlach, Darius A. and Frings-Meuthen, Petra and Maffiuletti, Nicola A. and Bloch, Wilhelm and Rittweger, J{\"o}rn}, title = {Using the Hephaistos orthotic device to study countermeasure effectiveness of neuromuscular electrical stimulation and dietary lupin protein supplementation, a randomised controlled trial}, series = {Plos one}, volume = {12}, journal = {Plos one}, number = {2}, doi = {10.1371/journal.pone.0171562}, year = {2017}, language = {en} } @article{KolditzAlbinBrueggemannetal.2016, author = {Kolditz, Melanie and Albin, Thivaharan and Br{\"u}ggemann, Gert-Peter and Abel, Dirk and Albracht, Kirsten}, title = {Robotergest{\"u}tztes System f{\"u}r ein verbessertes neuromuskul{\"a}res Aufbautraining der Beinstrecker}, series = {at - Automatisierungstechnik}, volume = {64}, journal = {at - Automatisierungstechnik}, number = {11}, publisher = {De Gruyter}, address = {Berlin}, issn = {2196-677X}, doi = {10.1515/auto-2016-0044}, pages = {905 -- 914}, year = {2016}, abstract = {Neuromuskul{\"a}res Aufbautraining der Beinstrecker ist ein wichtiger Bestandteil in der Rehabilitation und Pr{\"a}vention von Muskel-Skelett-Erkrankungen. Effektives Training erfordert hohe Muskelkr{\"a}fte, die gleichzeitig hohe Belastungen von bereits gesch{\"a}digten Strukturen bedeuten. Um trainingsinduzierte Sch{\"a}digungen zu vermeiden, m{\"u}ssen diese Kr{\"a}fte kontrolliert werden. Mit heutigen Trainingsger{\"a}ten k{\"o}nnen diese Ziele allerdings nicht erreicht werden. F{\"u}r ein sicheres und effektives Training sollen durch den Einsatz der Robotik, Sensorik, eines Regelkreises sowie Muskel-Skelett-Modellen Belastungen am Zielgewebe direkt berechnet und kontrolliert werden. Auf Basis zweier Vorstudien zu m{\"o}glichen Stellgr{\"o}ßen wird der Aufbau eines robotischen Systems vorgestellt, das sowohl f{\"u}r Forschungszwecke als auch zur Entwicklung neuartiger Trainingsger{\"a}te verwendet werden kann.}, language = {de} } @article{HacklWegmannKahmannetal.2017, author = {Hackl, Michael and Wegmann, Kilian and Kahmann, Stephanie Lucina and Heinze, Nicolai and Staat, Manfred and Neiss, Wolfram F. and Scaal, Martin and M{\"u}ller, Lars P.}, title = {Radial shortening osteotomy reduces radiocapitellar contact pressures while preserving valgus stability of the elbow}, series = {Knee Surgery, Sports Traumatology, Arthroscopy}, volume = {25}, journal = {Knee Surgery, Sports Traumatology, Arthroscopy}, number = {7}, publisher = {Springer}, address = {Berlin}, issn = {1433-7347}, doi = {10.1007/s00167-017-4468-z}, pages = {2280 -- 2288}, year = {2017}, language = {en} } @article{AlbrachtArampatzis2006, author = {Albracht, Kirsten and Arampatzis, Adamantios}, title = {Influence of the mechanical properties of the muscle-tendon unit on force generation in runners with different running economy}, series = {Biological Cybernetics}, volume = {95}, journal = {Biological Cybernetics}, number = {1}, issn = {1432-0770}, doi = {10.1007/s00422-006-0070-z}, pages = {87 -- 96}, year = {2006}, language = {en} } @article{ArampatzisKaramanidisAlbracht2007, author = {Arampatzis, Adamantios and Karamanidis, Kiros and Albracht, Kirsten}, title = {Adaptational responses of the human Achilles tendon by modulation of the applied cyclic strain magnitude}, series = {Journal of Experimental Biology}, volume = {210}, journal = {Journal of Experimental Biology}, number = {15}, issn = {0022-0949}, doi = {10.1242/jeb.003814}, pages = {2743 -- 2753}, year = {2007}, language = {en} } @article{AlbrachtArampatzisBaltzopoulos2008, author = {Albracht, Kirsten and Arampatzis, A. and Baltzopoulos, V.}, title = {Assessment of muscle volume and physiological cross-sectional area of the human triceps surae muscle in vivo}, series = {Journal of Biomechanics}, volume = {41}, journal = {Journal of Biomechanics}, issn = {0021-9290}, doi = {10.1016/j.jbiomech.2008.04.020}, pages = {2211 -- 2218}, year = {2008}, language = {en} } @article{ArampatzisKaramanidisMademlietal.2009, author = {Arampatzis, Adamantios and Karamanidis, Kiros and Mademli, Lida and Albracht, Kirsten}, title = {Plasticity of the human tendon to short and long-term mechanical loading}, series = {Exercise and Sport Sciences Reviews}, volume = {37}, journal = {Exercise and Sport Sciences Reviews}, number = {2}, issn = {1538-3008}, doi = {10.1097/JES.0b013e31819c2e1d}, pages = {66 -- 72}, year = {2009}, language = {en} } @article{AggeloussisGiannakouAlbrachtetal.2010, author = {Aggeloussis, Nickos and Giannakou, Erasmia and Albracht, Kirsten and Arampatzis, Adamantios}, title = {Reproducibility of fascicle length and pennation angle of gastrocnemius medialis in human gait in vivo}, series = {Gait and Posture}, volume = {31}, journal = {Gait and Posture}, number = {1}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0966-6362}, doi = {10.1016/j.gaitpost.2009.08.249}, pages = {73 -- 77}, year = {2010}, abstract = {The purpose of the current study was to examine the reproducibility of fascicle length and pennation angle of gastrocnemius medialis while human walking. To the best of our knowledge, this is the first study of the reproducibility of fascicle length and pennation angle of gastrocnemius medialis in vivo during human gait. Twelve males performed 10 gait trials on a treadmill, in 2 separate days. B-mode ultrasonography, with the ultrasound probe firmly adjusted in the transverse and frontal planes using a special cast, was used to measure the fascicle length and the pennation angle of the gastrocnemius medialis (GM). A Vicon 624 system with three cameras operating at 120 Hz was also used to record the ankle and knee joint angles. The results showed that measurements of fascicle length and pennation angle showed high reproducibility during the gait cycle, both within the same day and between different days. Moreover, the root mean square differences between the repeated waveforms of both variables were very small, compared with their ranges (fascicle length: RMS = ∼3 mm, range: 38-63 mm; pennation angle: RMS = ∼1.5°, range: 22-32°). However, their reproducibility was lower compared to the joint angles. It was found that representative data have to be derived by a wide number of gait trials (fascicle length ∼six trials, pennation angle more than 10 trials), to assure the reliability of the fascicle length and pennation angle in human gait.}, language = {en} }