@article{RatkeMilowLisinskietal.2014,
  author    = {Ratke, Lorenz and Milow, Barbara and Lisinski, Susanne and Hoepfner, Sandra},
  title     = {On an effect of fine ceramic particles on the structure of aerogels},
  series = {Microgravity science and technology},
  volume    = {26},
  journal   = {Microgravity science and technology},
  publisher = {Springer Nature},
  address   = {Heidelberg},
  issn      = {0938-0108 ; 1875-0494},
  doi       = {10.1007/s12217-014-9380-2},
  pages     = {103 -- 110},
  year      = {2014},
  language  = {en}
}
@article{AlmajhdiSengerAmeretal.2014,
  author    = {Almajhdi, Fahad N. and Senger, Tilo and Amer, Haitham M. and Gissmann, Lutz and {\"O}hlschl{\"a}ger, Peter},
  title     = {Design of a highly effective therapeutic HPV16 E6/E7-specific DNA vaccine: optimization by different ways of sequence rearrangements (Shuffling)},
  series = {PLOS one},
  volume    = {11},
  journal   = {PLOS one},
  number    = {9},
  publisher = {PLOS},
  address   = {San Francisco},
  issn      = {1932-6203},
  doi       = {10.1371/journal.pone.0113461},
  pages     = {e113461},
  year      = {2014},
  abstract  = {Persistent infection with the high-risk Human Papillomavirus type 16 (HPV 16) is the causative event for the development of cervical cancer and other malignant tumors of the anogenital tract and of the head and neck. Despite many attempts to develop therapeutic vaccines no candidate has entered late clinical trials. An interesting approach is a DNA based vaccine encompassing the nucleotide sequence of the E6 and E7 viral oncoproteins. Because both proteins are consistently expressed in HPV infected cells they represent excellent targets for immune therapy. Here we report the development of 8 DNA vaccine candidates consisting of differently rearranged HPV-16 E6 and E7 sequences within one molecule providing all naturally occurring epitopes but supposedly lacking transforming activity. The HPV sequences were fused to the J-domain and the SV40 enhancer in order to increase immune responses. We demonstrate that one out of the 8 vaccine candidates induces very strong cellular E6- and E7- specific cellular immune responses in mice and, as shown in regression experiments, efficiently controls growth of HPV 16 positive syngeneic tumors. This data demonstrates the potential of this vaccine candidate to control persistent HPV 16 infection that may lead to malignant disease. It also suggests that different sequence rearrangements influence the immunogenecity by an as yet unknown mechanism.},
  language  = {en}
}
@misc{ReyesOchoa2014,
  type      = {Master Thesis},
  author    = {Reyes Ochoa, Leonel},
  title     = {Engineering aspects of a parabolic trough collector field with direct steam generation and an organic rankine cycle},
  publisher = {Fachhochschule Aachen},
  address   = {Aachen},
  pages     = {X, 72 S.},
  year      = {2014},
  language  = {en}
}
@article{PoghossianBaeckerMayeretal.2015,
  author    = {Poghossian, Arshak and B{\"a}cker, Matthias and Mayer, Dirk and Sch{\"o}ning, Michael Josef},
  title     = {Gating capacitive field-effect sensors by the charge of nanoparticle/molecule hybrids},
  series = {Nanoscale},
  journal   = {Nanoscale},
  publisher = {Royal Society of Chemistry (RSC)},
  address   = {Cambridge},
  issn      = {2040-3372 (E-Journal); 2040-3364 (Print)},
  doi       = {10.1039/C4NR05987E},
  pages     = {1023 -- 1031},
  year      = {2015},
  language  = {en}
}
@inproceedings{VoronkovaBauerKotliar2014,
  author    = {Voronkova, Eva B. and Bauer, Svetlana M. and Kotliar, Konstantin},
  title     = {Computer simulation of the cornea-scleral shell as applied to pressure-volume relationship in the human eye},
  series = {2014 International Conference on Computer Technologies in Physical and Engineering Applications : ICCTPEA 2014 : proceedings : June 30 2014-July 4 2014, St. Petersburg},
  booktitle = {2014 International Conference on Computer Technologies in Physical and Engineering Applications : ICCTPEA 2014 : proceedings : June 30 2014-July 4 2014, St. Petersburg},
  organization    = {Institute of Electrical and Electronics Engineers},
  isbn      = {978-1-4799-5315-8},
  pages     = {204 -- 205},
  year      = {2014},
  language  = {en}
}
@inproceedings{BaeckerSchusserLeinhosetal.2014,
  author    = {B{\"a}cker, Matthias and Schusser, Sebastian and Leinhos, Marcel and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Sensor system for the monitoring of degradation processes of biodegradable biopolymers},
  series = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)},
  booktitle = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)},
  publisher = {VDE-Verl.},
  address   = {D{\"u}sseldorf},
  organization    = {VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik},
  isbn      = {978-3-8007-3622-5},
  pages     = {1 -- 4},
  year      = {2014},
  language  = {en}
}
@inproceedings{OberlaenderKirchnerKeusgenetal.2014,
  author    = {Oberl{\"a}nder, Jan and Kirchner, Patrick and Keusgen, M. and Sch{\"o}ning, Michael Josef},
  title     = {Flexible polyimide-based calorimetric gas sensors for monitoring hy-drogen peroxide in sterilisation processes of aseptic filling machines},
  series = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)},
  booktitle = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)},
  publisher = {VDE-Verl.},
  address   = {D{\"u}sseldorf},
  organization    = {VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik},
  isbn      = {978-3-8007-3622-5},
  pages     = {1 -- 4},
  year      = {2014},
  language  = {en}
}
@inproceedings{WuBronderPoghossianetal.2014,
  author    = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {DNA-hybridization detection using light-addressable potentiometric sensor modified with gold layer},
  series = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)},
  booktitle = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)},
  publisher = {VDE-Verl.},
  address   = {D{\"u}sseldorf},
  organization    = {VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik},
  isbn      = {978-3-8007-3622-5},
  pages     = {1 -- 4},
  year      = {2014},
  language  = {en}
}
@inproceedings{WernerYoshinobuMiyamotoetal.2014,
  author    = {Werner, Frederik and Yoshinobu, T. and Miyamoto, K. and Sch{\"o}ning, Michael Josef and Wagner, Torsten},
  title     = {Semiconductor-based sensors for imaging of chemical processes},
  series = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)},
  booktitle = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)},
  publisher = {VDE-Verl.},
  address   = {D{\"u}sseldorf},
  organization    = {VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik},
  isbn      = {978-3-8007-3622-5},
  pages     = {1 -- 5},
  year      = {2014},
  language  = {en}
}
@inproceedings{HuckPoghossianBuniatyanetal.2014,
  author    = {Huck, Christina and Poghossian, Arshak and Buniatyan, V. and Sch{\"o}ning, Michael Josef},
  title     = {Multi-parameter detection for supporting monitoring and control of biogas processes in agriculture},
  series = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)},
  booktitle = {Sensoren und Messsysteme 2014 ; Beitr{\"a}ge der 17. GMA/ITG-Fachtagung vom 3. bis 4. Juni 2014 in N{\"u}rnberg. (ITG-Fachbericht ; 250)},
  publisher = {VDE-Verl.},
  address   = {Berlin},
  organization    = {VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik},
  isbn      = {978-3-8007-3622-5},
  pages     = {1 -- 5},
  year      = {2014},
  language  = {en}
}
@incollection{SchoeningPoghossianGluecketal.2014,
  author    = {Sch{\"o}ning, Michael Josef and Poghossian, Arshak and Gl{\"u}ck, Olaf and Thust, Marion},
  title     = {Electrochemical methods for the determination of chemical variables in aqueous media},
  series = {Measurement, instrumentation, and sensors handbook / ed. by John G. Webster [u.a.] Vol. 2 : Electromagnetic, optical, radiation, chemical, and biomedical measurement},
  booktitle = {Measurement, instrumentation, and sensors handbook / ed. by John G. Webster [u.a.] Vol. 2 : Electromagnetic, optical, radiation, chemical, and biomedical measurement},
  publisher = {CRC Pr.},
  address   = {Boca Raton, Fla.},
  isbn      = {978-1-4398-4891-3},
  pages     = {55-1 -- 55-54},
  year      = {2014},
  language  = {en}
}
@incollection{KirchnerReisertSchoening2014,
  author    = {Kirchner, Patrick and Reisert, Steffen and Sch{\"o}ning, Michael Josef},
  title     = {Calorimetric gas sensors for hydrogen peroxide monitoring in aseptic food processes},
  series = {Gas sensing fundamentals. (Springer Series on Chemical Sensors and Biosensors ; 15)},
  booktitle = {Gas sensing fundamentals. (Springer Series on Chemical Sensors and Biosensors ; 15)},
  publisher = {Springer},
  address   = {Heidelberg},
  isbn      = {978-3-642-54518-4 (Print) ; 978-3-642-54519-1 (Online)},
  doi       = {10.1007/5346_2013_51},
  pages     = {279 -- 309},
  year      = {2014},
  abstract  = {For the sterilisation of aseptic food packages it is taken advantage of the microbicidal properties of hydrogen peroxide (H2O2). Especially, when applied in vapour phase, it has shown high potential of microbial inactivation. In addition, it offers a high environmental compatibility compared to other chemical sterilisation agents, as it decomposes into oxygen and water, respectively. Due to a lack in sensory detection possibilities, a continuous monitoring of the H2O2 concentration was recently not available. Instead, the sterilisation efficacy is validated using microbiological tests. However, progresses in the development of calorimetric gas sensors during the last 7 years have made it possible to monitor the H2O2 concentration during operation. This chapter deals with the fundamentals of calorimetric gas sensing with special focus on the detection of gaseous hydrogen peroxide. A sensor principle based on a calorimetric differential set-up is described. Special emphasis is given to the sensor design with respect to the operational requirements under field conditions. The state-of-the-art regarding a sensor set-up for the on-line monitoring and secondly, a miniaturised sensor for in-line monitoring are summarised. Furthermore, alternative detection methods and a novel multi-sensor system for the characterisation of aseptic sterilisation processes are described.},
  language  = {en}
}
@inproceedings{FunkeHajAyedKustereretal.2014,
  author    = {Funke, Harald and Haj Ayed, A. and Kusterer, K. and Keinz, Jan and Kazari, M. and Kitajima, J. and Horikawa, A. and Okada, K.},
  title     = {Numerical Study on Increased Energy Density for the DLN Micromix Hydrogen Combustion Principle},
  series = {Combustion, Fuels and Emissions (ASME Turbo Expo 2014: Turbine Technical Conference and Exposition : D{\"u}sseldorf, Germany, June 16-20, 2014 ; Vol. 4A)},
  booktitle = {Combustion, Fuels and Emissions (ASME Turbo Expo 2014: Turbine Technical Conference and Exposition : D{\"u}sseldorf, Germany, June 16-20, 2014 ; Vol. 4A)},
  publisher = {ASME},
  address   = {New York, N.Y.},
  isbn      = {978-0-7918-4568-4},
  pages     = {V04AT04A057},
  year      = {2014},
  language  = {en}
}
@article{KluczkaEcksteinAlexopoulosetal.2014,
  author    = {Kluczka, Sven and Eckstein, Julian and Alexopoulos, Spiros and Vaeßen, Christiane and Roeb, Martin},
  title     = {Process simulation for solar steam and dry reforming},
  series = {Energy procedia : Proceedings of the SolarPACES 2013 International Conference},
  volume    = {49},
  journal   = {Energy procedia : Proceedings of the SolarPACES 2013 International Conference},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1876-6102 (E-Journal)},
  doi       = {10.1016/j.egypro.2014.03.092},
  pages     = {850 -- 859},
  year      = {2014},
  abstract  = {In co-operation with the German Aerospace Center, the Solar-Institut J{\"u}lich has been analyzing the different technologies that are available for methanol production from CO2 using solar energy. The aim of the project is to extract CO2 from industrial exhaust gases or directly from the atmosphere to recycle it by use of solar energy. Part of the study was the modeling and simulating of a methane reformer for the production of synthesis gas, which can be operated by solar or hybrid heat sources. The reformer has been simplified in such a way that the model is accurate and enables fast calculations. The developed pseudo-homogeneous one- dimensional model can be regarded as a kind of counter-current heat exchanger and is able to incorporate a steam reforming reaction as well as a dry reforming reaction.},
  language  = {en}
}
@article{MuellerHirschfeldLambertzetal.2014,
  author    = {M{\"u}ller, Martin and Hirschfeld, Julian A. and Lambertz, Rita and Schulze Lohoff, Andreas and Lustfeld, Hans and Pfeifer, Heinz and Reißel, Martin},
  title     = {Validation of a novel method for detecting and stabilizing malfunctioning areas in fuel cell stacks},
  series = {Journal of power sources},
  volume    = {272},
  journal   = {Journal of power sources},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-2755 (E-Journal); 0378-7753 (Print)},
  doi       = {10.1016/j.jpowsour.2014.08.045},
  pages     = {225 -- 232},
  year      = {2014},
  abstract  = {In this paper a setup for detecting malfunctioning areas of MEAs in fuel cell stacks is described. Malfunctioning areas generate electric cross currents inside bipolar plates. To exploit this we suggest bipolar plates consisting not of two but of three layers. The third one is a highly conducting layer and segmented such that the cross currents move along the segments to the surface of the stack where they can be measured by an inductive sensor. With this information a realistic model can be used to detect the malfunctioning area. Furthermore the third layer will prevent any current inhomogeneity of a malfunctioning cell to spread to neighbouring cells in the stack. In this work the results of measurements in a realistic cell setup will be compared with the results obtained in simulation studies with the same configuration. The basis for the comparison is the reliable characterisation of the electrical properties of the cell components and the implication of these results into the simulation model. The experimental studies will also show the limits in the maximum number of segments, which can be used for a reliable detection of cross currents.},
  language  = {en}
}
@article{SchusserPoghossianBaeckeretal.2015,
  author    = {Schusser, Sebastian and Poghossian, Arshak and B{\"a}cker, Matthias and Krischer, M. and Leinhos, Marcel and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {An application of field-effect sensors for in-situ monitoring of degradation of biopolymers},
  series = {Sensors and actuators B: Chemical},
  volume    = {207, Part B},
  journal   = {Sensors and actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-3077 (E-Journal); 0925-4005 (Print)},
  doi       = {10.1016/j.snb.2014.10.058},
  pages     = {954 -- 959},
  year      = {2015},
  abstract  = {The characterization of the degradation kinetics of biodegradable polymers is mandatory with regard to their proper application. In the present work, polymer-modified electrolyte-insulator-semiconductor (PMEIS) field-effect sensors have been applied for in-situ monitoring of the pH-dependent degradation kinetics of the commercially available biopolymer poly(d,l-lactic acid) (PDLLA) in buffer solutions from pH 3 to pH 13. PDLLA films of 500 nm thickness were deposited on the surface of an Al-p-Si-SiO2-Ta2O5 structure from a polymer solution by means of spin-coating method. The PMEIS sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. A faster degradation has been observed for PDLLA films exposed to alkaline solutions (pH 9, pH 11 and pH 13).},
  language  = {en}
}
@inproceedings{LoPiparoKernMazzetti2012,
  author    = {Lo Piparo, G. B. and Kern, Alexander and Mazzetti, C.},
  title     = {Some masterpoints about risk due to lightning},
  series = {International Conference on Lightning Protection (ICLP) : 2 - 7 Sept. 2012, Vienna},
  booktitle = {International Conference on Lightning Protection (ICLP) : 2 - 7 Sept. 2012, Vienna},
  publisher = {IEEE},
  address   = {Piscataway, NJ},
  organization    = {International Conference on Lightning Protection <2012, Wien>},
  isbn      = {978-1-4673-1896-9 (E-Book) ; 978-1-4673-1898-3 (Print)},
  pages     = {1 -- 6},
  year      = {2012},
  language  = {en}
}
@inproceedings{KernSchelthoffMathieu2012,
  author    = {Kern, Alexander and Schelthoff, Christof and Mathieu, Moritz},
  title     = {Calculation of interception efficiencies for mesh-type air-terminations according to IEC 62305-3 using a dynamic electro-geometrical model},
  series = {International Conference on Lightning Protection (ICLP) : 2 - 7 Sept. 2012, Vienna},
  booktitle = {International Conference on Lightning Protection (ICLP) : 2 - 7 Sept. 2012, Vienna},
  publisher = {IEEE},
  address   = {Piscataway, NJ},
  organization    = {International Conference on Lightning Protection <2012, Wien>},
  isbn      = {978-1-4673-1896-9 (E-Book) ; 978-1-4673-1898-3 (Print)},
  pages     = {1 -- 6},
  year      = {2012},
  language  = {en}
}
@inproceedings{WetterKern2014,
  author    = {Wetter, Martin and Kern, Alexander},
  title     = {Number of lightning strikes to tall structures - comparison of calculations and measurements using a modern lightning monitoring system},
  series = {2014 International Conference on Lightning Protection (ICLP), Shanghai, China},
  booktitle = {2014 International Conference on Lightning Protection (ICLP), Shanghai, China},
  organization    = {International Conference on Lightning Protection <2014, Shanghai>},
  pages     = {1 -- 7},
  year      = {2014},
  language  = {en}
}
@article{KonstantinidisFloresMartinezDachwaldetal.2015,
  author    = {Konstantinidis, Konstantinos and Flores Martinez, Claudio and Dachwald, Bernd and Ohndorf, Andreas and Dykta, Paul and Bowitz, Pascal and Rudolph, Martin and Digel, Ilya and Kowalski, Julia and Voigt, Konstantin and F{\"o}rstner, Roger},
  title     = {A lander mission to probe subglacial water on Saturn's moon enceladus for life},
  series = {Acta astronautica},
  volume    = {Vol. 106},
  journal   = {Acta astronautica},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1879-2030 (E-Journal); 0094-5765 (Print)},
  pages     = {63 -- 89},
  year      = {2015},
  language  = {en}
}
@incollection{KnottSofroniaGerressenetal.2014,
  author    = {Knott, Thomas C. and Sofronia, Raluca E. and Gerressen, Marcus and Law, Yuen and Davidescu, Arjana and Savii, George G. and Gatzweiler, Karl-Heinz and Staat, Manfred and Kuhlen, Torsten W.},
  title     = {Preliminary bone sawing model for a virtual reality-based training simulator of bilateral sagittal split osteotomy},
  series = {Biomedical simulation : 6th International Symposium, ISBMS 2014, Strasbourg, France, October 16-17, 2014 : proceedings (Lecture notes in computer science : vol. 8789)},
  booktitle = {Biomedical simulation : 6th International Symposium, ISBMS 2014, Strasbourg, France, October 16-17, 2014 : proceedings (Lecture notes in computer science : vol. 8789)},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-12057-7 (Online)},
  doi       = {10.1007/978-3-319-12057-7_1},
  pages     = {1 -- 10},
  year      = {2014},
  abstract  = {Successful bone sawing requires a high level of skill and experience, which could be gained by the use of Virtual Reality-based simulators. A key aspect of these medical simulators is realistic force feedback. The aim of this paper is to model the bone sawing process in order to develop a valid training simulator for the bilateral sagittal split osteotomy, the most often applied corrective surgery in case of a malposition of the mandible. Bone samples from a human cadaveric mandible were tested using a designed experimental system. Image processing and statistical analysis were used for the selection of four models for the bone sawing process. The results revealed a polynomial dependency between the material removal rate and the applied force. Differences between the three segments of the osteotomy line and between the cortical and cancellous bone were highlighted.},
  language  = {en}
}
@inproceedings{SchirraWatmuffBauschat2014,
  author    = {Schirra, Julian and Watmuff, Jon and Bauschat, J.-Michael},
  title     = {A relative assessment of existing potential-methodologies to accurately estimate the induced drag of highly non-planar lifting systems},
  series = {Advanced aero concepts, design and operations : Applied Aerodynamics Conference : July 22 -24, 2014, Bristol, UK},
  booktitle = {Advanced aero concepts, design and operations : Applied Aerodynamics Conference : July 22 -24, 2014, Bristol, UK},
  organization    = {Applied Aerodynamics Conference <2014, Bristol>},
  pages     = {1 -- 13},
  year      = {2014},
  language  = {en}
}
@inproceedings{PieperSchulz2014,
  author    = {Pieper, Martin and Schulz, Silvia},
  title     = {Teaching Simulation Methods with COMSOL Multiphysics},
  organization    = {COMSOL Conference <2014, Cambridge>},
  pages     = {7},
  year      = {2014},
  abstract  = {This paper describes two courses on simulation methods for graduate students: "Simulation Methods" and "Simulation and Optimization in Virtual Engineering" The courses were planned to teach young engineers how to work with simulation software as well as to understand the necessary mathematical background. As simulation software COMSOL is used. The main philosophy was to combine theory and praxis in a way that motivates the students. In addition "soft skills" should be improved. This was achieved by project work as final examination. As underlying didactical principle the ideas of Bloom's revised taxonomy were followed. The paper basically focusses on educational aspects, e.g. how to structure the course, plan the exercises, organize the project work and include practical COMSOL examples.},
  language  = {en}
}
@article{HandtkeVollandMethlingetal.2014,
  author    = {Handtke, Stefan and Volland, Sonja and Methling, Karen and Albrecht, Dirk and Becher, D{\"o}rte and Nehls, Jenny and Bongaerts, Johannes and Maurer, Karl-Heinz and Lalk, Michael and Liesegang, Heiko and Voigt, Birgit and Daniel, Rolf and Hecker, Michael},
  title     = {Cell physiology of the biotechnological relevant bacterium Bacillus pumilus - An omics-based approach},
  series = {Journal of Biotechnology},
  journal   = {Journal of Biotechnology},
  number    = {192(A)},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-4863 (E-Journal); 0168-1656 (Print)},
  doi       = {10.1016/j.jbiotec.2014.08.028},
  pages     = {204 -- 214},
  year      = {2014},
  abstract  = {Members of the species Bacillus pumilus get more and more in focus of the biotechnological industry as potential new production strains. Based on exoproteome analysis, B. pumilus strain Jo2, possessing a high secretion capability, was chosen for an omics-based investigation. The proteome and metabolome of B. pumilus cells growing either in minimal or complex medium was analyzed. In total, 1542 proteins were identified in growing B. pumilus cells, among them 1182 cytosolic proteins, 297 membrane and lipoproteins and 63 secreted proteins. This accounts for about 43\% of the 3616 proteins encoded in the B. pumilus Jo2 genome sequence. By using GC-MS, IP-LC/MS and H NMR methods numerous metabolites were analyzed and assigned to reconstructed metabolic pathways. In the genome sequence a functional secretion system including the components of the Sec- and Tat-secretion machinery was found. Analysis of the exoproteome revealed secretion of about 70 proteins with predicted secretion signals. In addition, selected production-relevant genome features such as restriction modification systems and NRPS clusters of B. pumilus Jo2 are discussed.},
  language  = {en}
}
@inproceedings{PfaffVinsonneauBurnham2006,
  author    = {Pfaff, Raphael and Vinsonneau, B. and Burnham, K. J.},
  title     = {Multiple models for nonlinear systems},
  series = {Proceedings / Eigteenth International Conference on Systems Engineering : ICSE 2006 : 5 - 7 September 2006 ; [held at Coventry University, UK]},
  booktitle = {Proceedings / Eigteenth International Conference on Systems Engineering : ICSE 2006 : 5 - 7 September 2006 ; [held at Coventry University, UK]},
  organization    = {International Conference on Systems Engineering <18, 2006, Coventry>},
  isbn      = {1-84600-013-0},
  pages     = {347 -- 352},
  year      = {2006},
  language  = {en}
}
@article{MarxSchenkBehrensetal.2013,
  author    = {Marx, Ulrich and Schenk, Friedrich and Behrens, Jan and Meyr, Ulrike and Wanek, Paul and Zang, Werner and Schmitt, Robert and Br{\"u}stle, Oliver and Zenke, Martin and Klocke, Fritz},
  title     = {Automatic production of induced pluripotent stem cells},
  series = {Procedia CIRP : First CIRP Conference on BioManufacturing},
  volume    = {Vol. 5},
  journal   = {Procedia CIRP : First CIRP Conference on BioManufacturing},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {2212-8271},
  pages     = {2 -- 6},
  year      = {2013},
  language  = {en}
}
@article{MuribYeapMartensetal.2014,
  author    = {Murib, Mohammed Sharif and Yeap, Weng-Siang and Martens, Daan and Bienstman, Peter and Ceuninck, Ward de and Grinsven, Bart van and Sch{\"o}ning, Michael Josef and Michiels, Luc and Haenen, Ken and Ameloot, Marcel and Serpeng{\"u}zel, Ali and Wagner, Patrick},
  title     = {Photonic detection and characterization of DNA using sapphire microspheres},
  series = {Journal of biomedical optics},
  volume    = {19},
  journal   = {Journal of biomedical optics},
  number    = {9},
  publisher = {SPIE},
  address   = {Bellingham},
  issn      = {1560-2281 (E-Journal); 1083-3668 (Print)},
  doi       = {10.1117/1.JBO.19.9.097006},
  pages     = {097006},
  year      = {2014},
  abstract  = {A microcavity-based deoxyribonucleic acid (DNA) optical biosensor is demonstrated for the first time using synthetic sapphire for the optical cavity. Transmitted and elastic scattering intensity at 1510 nm are analyzed from a sapphire microsphere (radius 500  μm, refractive index 1.77) on an optical fiber half coupler. The 0.43 nm angular mode spacing of the resonances correlates well with the optical size of the sapphire sphere. Probe DNA consisting of a 36-mer fragment was covalently immobilized on a sapphire microsphere and hybridized with a 29-mer target DNA. Whispering gallery modes (WGMs) were monitored before the sapphire was functionalized with DNA and after it was functionalized with single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). The shift in WGMs from the surface modification with DNA was measured and correlated well with the estimated thickness of the add-on DNA layer. It is shown that ssDNA is more uniformly oriented on the sapphire surface than dsDNA. In addition, it is shown that functionalization of the sapphire spherical surface with DNA does not affect the quality factor (Q≈104) of the sapphire microspheres. The use of sapphire is especially interesting because this material is chemically resilient, biocompatible, and widely used for medical implants.},
  language  = {en}
}
@article{SiqueiraMolinnusBegingetal.2014,
  author    = {Siqueira, Jose R. and Molinnus, Denise and Beging, Stefan and Sch{\"o}ning, Michael Josef},
  title     = {Incorporating a hybrid urease-carbon nanotubes sensitive nanofilm on capacitive field-effect sensors for urea detection},
  series = {Analytical chemistry},
  volume    = {86},
  journal   = {Analytical chemistry},
  number    = {11},
  publisher = {ACS Publications},
  address   = {Columbus},
  issn      = {1520-6882 (E-Journal); 0003-2700 (Print); 0096-4484 (Print)},
  doi       = {10.1021/ac500458s},
  pages     = {5370 -- 5375},
  year      = {2014},
  abstract  = {The ideal combination among biomolecules and nanomaterials is the key for reaching biosensing units with high sensitivity. The challenge, however, is to find out a stable and sensitive film architecture that can be incorporated on the sensor's surface. In this paper, we report on the benefits of incorporating a layer-by-layer (LbL) nanofilm of polyamidoamine (PAMAM) dendrimer and carbon nanotubes (CNTs) on capacitive electrolyte-insulator-semiconductor (EIS) field-effect sensors for detecting urea. Three sensor arrangements were studied in order to investigate the adequate film architecture, involving the LbL film with the enzyme urease: (i) urease immobilized directly onto a bare EIS [EIS-urease] sensor; (ii) urease atop the LbL film over the EIS [EIS-(PAMAM/CNT)-urease] sensor; and (iii) urease sandwiched between the LbL film and another CNT layer [EIS-(PAMAM/CNT)-urease-CNT]. The surface morphology of all three urea-based EIS biosensors was investigated by atomic force microscopy (AFM), while the biosensing abilities were studied by means of capacitance-voltage (C/V) and dynamic constant-capacitance (ConCap) measureaments at urea concentrations ranging from 0.1 mM to 100 mM. The EIS-urease and EIS-(PAMAM/CNT)-urease sensors showed similar sensitivity (∼18 mV/decade) and a nonregular signal behavior as the urea concentration increased. On the other hand, the EIS-(PAMAM/CNT)-urease-CNT sensor exhibited a superior output signal performance and higher sensitivity of about 33 mV/decade. The presence of the additional CNT layer was decisive to achieve a urea based EIS sensor with enhanced properties. Such sensitive architecture demonstrates that the incorporation of an adequate hybrid enzyme-nanofilm as sensing unit opens new prospects for biosensing applications using the field-effect sensor platform.},
  language  = {en}
}
@article{SrivastavaLahiriMaitietal.2014,
  author    = {Srivastava, A. and Lahiri, S. and Maiti, M. and Knolle, F. and Hoyler, Friedrich and Scherer, Ulrich W. and Schnug, E. W.},
  title     = {Study of naturally occurring radioactive material (NORM) in top soil of Punjab State from the North Western part of India},
  series = {Journal of Radioanalytical and Nuclear Chemistry},
  volume    = {2014},
  journal   = {Journal of Radioanalytical and Nuclear Chemistry},
  number    = {302},
  publisher = {Springer Nature},
  address   = {Basel},
  issn      = {1588-2780 (E-Journal); 0022-4081 (Print); 0134-0719 (Print); 0236-5731 (Print); 1417-2097 (Print)},
  doi       = {0.1007/s10967-014-3450-1},
  pages     = {1049 -- 1052},
  year      = {2014},
  language  = {en}
}
@incollection{FrotscherGossmannRaatschenetal.2015,
  author    = {Frotscher, Ralf and Goßmann, Matthias and Raatschen, Hans-J{\"u}rgen and Temiz Artmann, Ayseg{\"u}l and Staat, Manfred},
  title     = {Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM},
  series = {Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)},
  booktitle = {Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)},
  publisher = {Springer},
  address   = {Heidelberg},
  isbn      = {978-3-319-02534-6 ; 978-3-319-02535-3},
  pages     = {187 -- 212},
  year      = {2015},
  abstract  = {We present an electromechanically coupled Finite Element model for cardiac tissue. It bases on the mechanical model for cardiac tissue of Hunter et al. that we couple to the McAllister-Noble-Tsien electrophysiological model of purkinje fibre cells. The corresponding system of ordinary differential equations is implemented on the level of the constitutive equations in a geometrically and physically nonlinear version of the so-called edge-based smoothed FEM for plates. Mechanical material parameters are determined from our own pressure-deflection experimental setup. The main purpose of the model is to further examine the experimental results not only on mechanical but also on electrophysiological level down to ion channel gates. Moreover, we present first drug treatment simulations and validate the model with respect to the experiments.},
  language  = {en}
}
@article{FateriGebhardtThuemmleretal.2014,
  author    = {Fateri, Miranda and Gebhardt, Andreas and Th{\"u}mmler, Stefan and Thurn, Laura},
  title     = {Experimental investigation on selective laser melting of glass},
  series = {Physics procedia : 8th International Conference on Laser Assisted Net Shape Engineering LANE 2014},
  volume    = {56 (2014)},
  journal   = {Physics procedia : 8th International Conference on Laser Assisted Net Shape Engineering LANE 2014},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1875-3892 (E-Journal); 1875-3884 (Print)},
  doi       = {10.1016/j.phpro.2014.08.118},
  pages     = {357 -- 364},
  year      = {2014},
  language  = {en}
}
@article{NachtrodtTietschMostaccietal.2014,
  author    = {Nachtrodt, Frederik and Tietsch, Wolfgang and Mostacci, Domiziano and Scherer, Ulrich W.},
  title     = {Set-up and first operation of a plasma oven for treatment of low level radioactive wastes},
  series = {Nuclear technology and radiation protection},
  volume    = {29},
  journal   = {Nuclear technology and radiation protection},
  number    = {Suppl.},
  publisher = {VINČA Institute of Nuclear Sciences},
  address   = {Belgrad},
  issn      = {1451-3994},
  doi       = {10.2298/NTRP140SS47N},
  pages     = {47 -- 51},
  year      = {2014},
  language  = {en}
}
@article{YoshinobuMiyamotoWagneretal.2015,
  author    = {Yoshinobu, Tatsuo and Miyamoto, Ko-ichiro and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Recent developments of chemical imaging sensor systems based on the principle of the light-addressable potentiometric sensor},
  series = {Sensors and actuators B: Chemical},
  volume    = {207, Part B},
  journal   = {Sensors and actuators B: Chemical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1873-3077 (E-Journal); 0925-4005 (Print)},
  doi       = {10.1016/j.snb.2014.09.002},
  pages     = {926 -- 932},
  year      = {2015},
  abstract  = {The light-addressable potentiometric sensor (LAPS) is an electrochemical sensor with a field-effect structure to detect the variation of the Nernst potential at its sensor surface, the measured area on which is defined by illumination. Thanks to this light-addressability, the LAPS can be applied to chemical imaging sensor systems, which can visualize the two-dimensional distribution of a particular target ion on the sensor surface. Chemical imaging sensor systems are expected to be useful for analysis of reaction and diffusion in various electrochemical and biological samples. Recent developments of LAPS-based chemical imaging sensor systems, in terms of the spatial resolution, measurement speed, image quality, miniaturization and integration with microfluidic devices, are summarized and discussed.},
  language  = {en}
}
@article{SeilerPichlerPfaffetal.2009,
  author    = {Seiler, Friedrich and Pichler, Alexander and Pfaff, Raphael and Srulijes, Julio},
  title     = {Novel processing tools for automated doppler picture velocimetry (DPV) evaluation},
  series = {Journal of visualization},
  volume    = {Vol. 12},
  journal   = {Journal of visualization},
  number    = {Iss. 4},
  issn      = {1343-8875},
  pages     = {323 -- 337},
  year      = {2009},
  language  = {en}
}
@article{PfaffBurnham2009,
  author    = {Pfaff, Raphael and Burnham, Keith J.},
  title     = {On abstraction and interpretability: a behavioural perspective},
  series = {Systems Science},
  volume    = {Vol. 35},
  journal   = {Systems Science},
  number    = {Iss. 2},
  issn      = {0137-1223},
  pages     = {19 -- 26},
  year      = {2009},
  language  = {en}
}
@inproceedings{PfaffBurnham2008,
  author    = {Pfaff, Raphael and Burnham, Keith J.},
  title     = {On abstraction and interpretability: a behavioural perspective},
  series = {19th International Conference on Systems Engineering 2008 : ICSENG '08 : 19 - 21 Aug. 2008, University of Nevada, Las Vegas, Nevada},
  booktitle = {19th International Conference on Systems Engineering 2008 : ICSENG '08 : 19 - 21 Aug. 2008, University of Nevada, Las Vegas, Nevada},
  publisher = {IEEE},
  address   = {Piscataway, NJ},
  organization    = {International Conference on Systems Engineering <19, 2008, Las Vegas, Nev.>},
  isbn      = {978-0-7695-3331-5 ; 978-0-7695-2719-2},
  pages     = {89 -- 94},
  year      = {2008},
  language  = {en}
}
@inproceedings{PfaffPichlerGeorgeetal.2007,
  author    = {Pfaff, Raphael and Pichler, Alexander and George, Alfred and Seiler, Friedrich},
  title     = {Model based image processing for flow visualisation : 16th International Conference on Systems Science, Wroclaw, Poland, September 04 - 06, 2007},
  series = {PU / Institut Franco-Allemand de Recherches de Saint-Louis ; 2007, 620},
  booktitle = {PU / Institut Franco-Allemand de Recherches de Saint-Louis ; 2007, 620},
  publisher = {ISL},
  address   = {Saint Louis, France},
  organization    = {International Conference on Systems Science <16, 2007, Wroclaw>},
  pages     = {1 -- 10},
  year      = {2007},
  language  = {en}
}
@inproceedings{SeilerPichlerPfaffetal.2008,
  author    = {Seiler, Friedrich and Pichler, Alexander and Pfaff, Raphael and George, Alfred and Srulijes, Julio},
  title     = {Improved Doppler picture velocimetry and new automated processing},
  series = {14th International Symposium on Applications of Laser Techniques to Fluid Mechanics : Lisbon, Portugal, 7 - 10 July 2008},
  booktitle = {14th International Symposium on Applications of Laser Techniques to Fluid Mechanics : Lisbon, Portugal, 7 - 10 July 2008},
  organization    = {International Symposium on Applications of Laser Techniques to Fluid Mechanics <14, 2008, Lisboa>},
  pages     = {1 -- 12},
  year      = {2008},
  language  = {en}
}
@inproceedings{PfaffLarkowskiBurnham2010,
  author    = {Pfaff, Raphael and Larkowski, Tomasz and Burnham, Keith J.},
  title     = {An approach to adaptive control in the behavioural framework},
  series = {UKACC International Conference on Control 2010 (CONTROL 2010) : Coventry, United Kingdom, 7 - 10 September 2010 ; Vol. 2. (IET seminar digest ; 2010/004)},
  booktitle = {UKACC International Conference on Control 2010 (CONTROL 2010) : Coventry, United Kingdom, 7 - 10 September 2010 ; Vol. 2. (IET seminar digest ; 2010/004)},
  publisher = {Curran},
  address   = {Red Hook, NY},
  organization    = {United Kingdom Automatic Control Council},
  isbn      = {978-1-62748-119-9},
  pages     = {833 -- 838},
  year      = {2010},
  language  = {en}
}
@inproceedings{PfaffLarkowskiBurnham2011,
  author    = {Pfaff, Raphael and Larkowski, Tomasz and Burnham, Keith J.},
  title     = {An application of adaptive control in the behavioural framework},
  series = {21st International Conference on Systems Engineering (ICSEng) : 16 - 18 Aug. 2011, Las Vegas, Nevada ; proceedings},
  booktitle = {21st International Conference on Systems Engineering (ICSEng) : 16 - 18 Aug. 2011, Las Vegas, Nevada ; proceedings},
  publisher = {IEEE},
  address   = {Piscataway, NJ},
  organization    = {International Conference on Systems Engineering <21, 2011, Las Vegas>},
  isbn      = {978-1-4577-1078-0 ; 978-0-7695-4495-3},
  pages     = {49 -- 54},
  year      = {2011},
  language  = {en}
}
@misc{Pfaff2006,
  type      = {Master Thesis},
  author    = {Pfaff, Raphael},
  title     = {Modelling of nonlinear systems using piecewise defined models},
  year      = {2006},
  language  = {en}
}
@masterthesis{Pfaff2007,
  type      = {Bachelor Thesis},
  author    = {Pfaff, Raphael},
  title     = {Automated processing of the ISL Doppler images},
  year      = {2007},
  language  = {en}
}
@phdthesis{Pfaff2013,
  author    = {Pfaff, Raphael},
  title     = {Evaluation and extension of the potential for application of the behavioural framework to practical engineering problems},
  pages     = {XVI, 231 S.},
  year      = {2013},
  language  = {en}
}
@misc{BesslerMaurerMerkeletal.2009,
  author    = {Bessler, Cornelius and Maurer, Karl-Heinz and Merkel, Marion and Siegert, Petra and Wieland, Susanne},
  title     = {Subtilisin from Bacillus Pumilus and detergent and cleaning agents containing said novel subtilisin [US Patentanmeldung / Internationale Patentanmeldung]},
  publisher = {USPTO; WIPO},
  address   = {Washington; Genf},
  pages     = {1 -- 39},
  year      = {2009},
  language  = {en}
}
@inproceedings{BuniatyanHuckPoghossianetal.2014,
  author    = {Buniatyan, V. V. and Huck, Christina and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Rustamyan, L. G. and Hovnikyan, H. H.},
  title     = {Equivalent circuit and optimization of impedance characteristics of an electrolyte conductivity sensor},
  series = {Proceedings of State Engineering University Armenia : Series Information technologies, electronics, radio engineering},
  volume    = {Iss. 17},
  booktitle = {Proceedings of State Engineering University Armenia : Series Information technologies, electronics, radio engineering},
  number    = {No. 1},
  pages     = {69 -- 76},
  year      = {2014},
  language  = {en}
}
@article{StadlerGarveyEmbsetal.2014,
  author    = {Stadler, Alexander Maximilian and Garvey, Christopher J. and Embs, Jan Peter and Koza, Michael Marek and Unruh, Tobias and Artmann, Gerhard and Zaccai, Guiseppe},
  title     = {Picosecond dynamics in haemoglobin from different species: A quasielastic neutron scattering study},
  series = {Biochimica et biophysica acta (BBA): General Subjects},
  volume    = {1840},
  journal   = {Biochimica et biophysica acta (BBA): General Subjects},
  number    = {10},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1872-8006 (E-Journal); 0304-4165 (Print)},
  doi       = {10.1016/j.bbagen.2014.06.007},
  pages     = {2989 -- 2999},
  year      = {2014},
  language  = {en}
}
@article{HoltrupSadeghfamHeuermannetal.2014,
  author    = {Holtrup, S. and Sadeghfam, Arash and Heuermann, Holger and Awakowicz, P.},
  title     = {Characterization and optimization technique for microwave-driven high-intensity discharge lamps using hot S-parameters},
  series = {IEEE transactions on microwave theories and techniques},
  volume    = {62},
  journal   = {IEEE transactions on microwave theories and techniques},
  number    = {10},
  publisher = {IEEE},
  address   = {New York},
  issn      = {0018-9480},
  doi       = {10.1109/TMTT.2014.2342652},
  pages     = {2471 -- 2480},
  year      = {2014},
  abstract  = {High-intensity discharge lamps can be driven by radio-frequency signals in the ISM frequency band at 2.45 GHz, using a matching network to transform the impedance of the plasma to the source impedance. To achieve an optimal operating condition, a good characterization of the lamp in terms of radio frequency equivalent circuits under operating conditions is necessary, enabling the design of an efficient matching network. This paper presents the characterization technique for such lamps and presents the design of the required matching network. For the characterization, a high-intensity discharge lamp was driven by a monofrequent large signal at 2.45 GHz, whereas a frequency sweep over 300 MHz was performed across this signal to measure so-called small-signal hot S-parameters using a vector network analyzer. These parameters are then used as an equivalent load in a circuit simulator to design an appropriate matching network. Using the measured data as a black-box model in the simulation results in a quick and efficient method to simulate and design efficient matching networks in spite of the complex plasma behavior. Furthermore, photometric analysis of high-intensity discharge lamps are carried out, comparing microwave operation to conventional operation.},
  language  = {en}
}
@article{KhaydukovaZadorozhnayaKirsanovetal.2014,
  author    = {Khaydukova, M. M. and Zadorozhnaya, O. A. and Kirsanov, D. O. and Iken, Heiko and Rolka, David and Sch{\"o}ning, Michael Josef and Babain, V. A. and Vlasov, Yu. G. and Legin, A. V.},
  title     = {Multivariate processing of atomic-force microscopy images for detection of the response of plasticized polymeric membranes},
  series = {Russian journal of applied chemistry},
  volume    = {87},
  journal   = {Russian journal of applied chemistry},
  number    = {3},
  publisher = {Springer},
  address   = {Dordrecht},
  issn      = {1608-3296 (E-Journal); 1070-4272 (Print)},
  doi       = {10.1134/S1070427214030112},
  pages     = {307 -- 314},
  year      = {2014},
  abstract  = {The possibility of using the atomic-force microscopy as a method for detection of the analytical signal from plasticized polymeric sensor membranes was analyzed. The surfaces of cadmium-selective membranes based on two polymeric matrices were examined. The digital images were processed with multivariate image analysis techniques. A correlation was found between the surface profile of an ion-selective membrane and the concentration of the ion in solution.},
  language  = {en}
}
@incollection{NiemuellerEwertReuteretal.2014,
  author    = {Niem{\"u}ller, Tim and Ewert, Daniel and Reuter, Sebastian and Ferrein, Alexander and Jeschke, Sabina and Lakemeyer, Gerhard},
  title     = {RoboCup logistics league sponsored by festo: A competitive factory automation testbed},
  series = {RoboCup 2013: Robot World Cup XVII : Eindhoven; Netherlands; 1 July 2013 through 1 July 2013. (Lecture notes in computer science ; 8371)},
  booktitle = {RoboCup 2013: Robot World Cup XVII : Eindhoven; Netherlands; 1 July 2013 through 1 July 2013. (Lecture notes in computer science ; 8371)},
  publisher = {Springer},
  address   = {Berlin},
  organization    = {RoboCup International Symposium <17, 2013, Eindhoven>},
  isbn      = {978-3-662-44467-2 (Print) 978-3-662-44468-9 (Online)},
  pages     = {336 -- 347},
  year      = {2014},
  abstract  = {A new trend in automation is to deploy so-called cyber-physical systems (CPS) which combine computation with physical processes. The novel RoboCup Logistics League Sponsored by Festo (LLSF) aims at such CPS logistic scenarios in an automation setting. A team of robots has to produce products from a number of semi-finished products which they have to machine during the game. Different production plans are possible and the robots need to recycle scrap byproducts. This way, the LLSF is a very interesting league offering a number of challenging research questions for planning, coordination, or communication in an application-driven scenario. In this paper, we outline the objectives of the LLSF and present steps for developing the league further towards a benchmark for logistics scenarios for CPS. As a major milestone we present the new automated referee system which helps in governing the game play as well as keeping track of the scored points in a very complex factory scenario.},
  language  = {en}
}
@article{ReisertGeisslerWeileretal.2015,
  author    = {Reisert, Steffen and Geissler, H. and Weiler, C. and Wagner, P. and Sch{\"o}ning, Michael Josef},
  title     = {Multiple sensor-type system for monitoring the microbicidal effectiveness of aseptic sterilisation processes},
  series = {Food control},
  volume    = {47},
  journal   = {Food control},
  issn      = {1873-7129 (E-Journal); 0956-7135 (Print)},
  doi       = {10.1016/j.foodcont.2014.07.063},
  pages     = {615 -- 622},
  year      = {2015},
  abstract  = {The present work describes a novel multiple sensor-type system for the real-time analysis of aseptic sterilisation processes employing gaseous hydrogen peroxide (H2O2) as a sterilant. The inactivation kinetics of Bacillus atrophaeus by gaseous H2O2 have been investigated by means of a methodical calibration experiment, taking into account the process variables H2O2 concentration, humidity and gas temperature. It has been found that the microbicidal effectiveness at H2O2 concentrations above 2\% v/v is largely determined by the concentration itself, while at lower H2O2 concentrations, the gas temperature and humidity play a leading role. Furthermore, the responses of different types of gas sensors towards the influencing factors of the sterilisation process have been analysed within the same experiment. Based on a correlation established between the inactivation kinetics and the sensor responses, a calorimetric H2O2 sensor and a metal-oxide semiconductor (MOX) sensor have been identified as possible candidates for monitoring the microbicidal effectiveness of aseptic sterilisation processes employing gaseous H2O2. Therefore, two linear models that describe the relationship between sensor response and microbicidal effectiveness have been proposed.},
  language  = {en}
}