@article{PoghossianJablonskiKochetal.2018,
  author    = {Poghossian, Arshak and Jablonski, Melanie and Koch, Claudia and Bronder, Thomas and Rolka, David and Wege, Christina and Sch{\"o}ning, Michael Josef},
  title     = {Field-effect biosensor using virus particles as scaffolds for enzyme immobilization},
  series = {Biosensors and Bioelectronics},
  volume    = {110},
  journal   = {Biosensors and Bioelectronics},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0956-5663},
  doi       = {10.1016/j.bios.2018.03.036},
  pages     = {168 -- 174},
  year      = {2018},
  abstract  = {A field-effect biosensor employing tobacco mosaic virus (TMV) particles as scaffolds for enzyme immobilization is presented. Nanotubular TMV scaffolds allow a dense immobilization of precisely positioned enzymes with retained activity. To demonstrate feasibility of this new strategy, a penicillin sensor has been developed by coupling a penicillinase with virus particles as a model system. The developed field-effect penicillin biosensor consists of an Al-p-Si-SiO₂-Ta₂O₅-TMV structure and has been electrochemically characterized in buffer solutions containing different concentrations of penicillin G. In addition, the morphology of the biosensor surface with virus particles was characterized by scanning electron microscopy and atomic force microscopy methods. The sensors possessed a high penicillin sensitivity of ~ 92 mV/dec in a nearly-linear range from 0.1 mM to 10 mM, and a low detection limit of about 50 µM. The long-term stability of the penicillin biosensor was periodically tested over a time period of about one year without any significant loss of sensitivity. The biosensor has also been successfully applied for penicillin detection in bovine milk samples.},
  language  = {en}
}
@article{RabehiGarlanAchtsnichtetal.2018,
  author    = {Rabehi, Amine and Garlan, Benjamin and Achtsnicht, Stefan and Krause, Hans-Joachim and Offenh{\"a}usser, Andreas and Ngo, Kieu and Neveu, Sophie and Graff-Dubois, Stephanie and Kokabi, Hamid},
  title     = {Magnetic detection structure for Lab-on-Chip applications based on the frequency mixing technique},
  series = {Sensors},
  volume    = {18},
  journal   = {Sensors},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s18061747},
  pages     = {14 Seiten},
  year      = {2018},
  abstract  = {A magnetic frequency mixing technique with a set of miniaturized planar coils was investigated for use with a completely integrated Lab-on-Chip (LoC) pathogen sensing system. The system allows the detection and quantification of superparamagnetic beads. Additionally, in terms of magnetic nanoparticle characterization ability, the system can be used for immunoassays using the beads as markers. Analytical calculations and simulations for both excitation and pick-up coils are presented; the goal was to investigate the miniaturization of simple and cost-effective planar spiral coils. Following these calculations, a Printed Circuit Board (PCB) prototype was designed, manufactured, and tested for limit of detection, linear response, and validation of theoretical concepts. Using the magnetic frequency mixing technique, a limit of detection of 15 µg/mL of 20 nm core-sized nanoparticles was achieved without any shielding.},
  language  = {en}
}
@article{BhattaraiStaat2018,
  author    = {Bhattarai, Aroj and Staat, Manfred},
  title     = {Computational comparison of different textile implants to correct apical prolapse in females},
  series = {Current Directions in Biomedical Engineering},
  volume    = {4},
  journal   = {Current Directions in Biomedical Engineering},
  number    = {1},
  publisher = {De Gruyter},
  address   = {Berlin},
  doi       = {10.1515/cdbme-2018-0159},
  pages     = {661 -- 664},
  year      = {2018},
  abstract  = {Prosthetic textile implants of different shapes, sizes and polymers are used to correct the apical prolapse after hysterectomy (removal of the uterus). The selection of the implant before or during minimally invasive surgery depends on the patient's anatomical defect, intended function after reconstruction and most importantly the surgeon's preference. Weakness or damage of the supporting tissues during childbirth, menopause or previous pelvic surgeries may put females in higher risk of prolapse. Numerical simulations of reconstructed pelvic floor with weakened tissues and organ supported by textile product models: DynaMesh®-PRS soft, DynaMesh®-PRP soft and DynaMesh®-CESA from FEG Textiletechnik mbH, Germany are compared.},
  language  = {en}
}
@article{HorbachStaat2018,
  author    = {Horbach, Andreas and Staat, Manfred},
  title     = {Optical strain measurement for the modeling of surgical meshes and their porosity},
  series = {Current Directions in Biomedical Engineering},
  volume    = {Band 4},
  journal   = {Current Directions in Biomedical Engineering},
  number    = {1},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {2364-5504},
  doi       = {10.1515/cdbme-2018-0045},
  pages     = {181 -- 184},
  year      = {2018},
  abstract  = {The porosity of surgical meshes makes them flexible for large elastic deformation and establishes the healing conditions of good tissue in growth. The biomechanic modeling of orthotropic and compressible materials requires new materials models and simulstaneoaus fit of deformation in the load direction as well as trannsversely to to load. This nonlinear modeling can be achieved by an optical deformation measurement. At the same time the full field deformation measurement allows the dermination of the change of porosity with deformation. Also the socalled effective porosity, which has been defined to asses the tisssue interatcion with the mesh implants, can be determined from the global deformation of the surgical meshes.},
  language  = {en}
}
@inproceedings{RichterBraunsteinStaeudleetal.2018,
  author    = {Richter, Charlotte and Braunstein, Bjoern and St{\"a}udle, Benjamin and Attias, Julia and Suess, Alexander and Weber, T. and Rittweger, Joern and Green, David A. and Albracht, Kirsten},
  title     = {In vivo fascicle length of the gastrocnemius muscle during walking in simulated martian gravity using two different body weight support devices},
  series = {23rd Annual Congress of the European College of Sport Science, Dublin, Irland},
  booktitle = {23rd Annual Congress of the European College of Sport Science, Dublin, Irland},
  year      = {2018},
  language  = {en}
}
@incollection{TranTranMatthiesetal.2017,
  author    = {Tran, N. T. and Tran, Thanh Ngoc and Matthies, M. G. and Stavroulakis, G. E. and Staat, Manfred},
  title     = {Shakedown Analysis Under Stochastic Uncertainty by Chance Constrained Programming},
  series = {Advances in Direct Methods for Materials and Structures},
  booktitle = {Advances in Direct Methods for Materials and Structures},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-59810-9},
  doi       = {10.1007/978-3-319-59810-9_6},
  pages     = {85 -- 103},
  year      = {2017},
  abstract  = {In this paper we propose a stochastic programming method to analyse limit and shakedown of structures under uncertainty condition of strength. Based on the duality theory, the shakedown load multiplier formulated by the kinematic theorem is proved actually to be the dual form of the shakedown load multiplier formulated by static theorem. In this investigation a dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit and the shakedown limit. The edge-based smoothed finite element method (ES-FEM) with three-node linear triangular elements is used for structural analysis.},
  language  = {en}
}
@article{HacklWegmannKahmannetal.2017,
  author    = {Hackl, Michael and Wegmann, Kilian and Kahmann, Stephanie Lucina and Heinze, Nicolai and Staat, Manfred and Neiss, Wolfram F. and Scaal, Martin and M{\"u}ller, Lars P.},
  title     = {Radial shortening osteotomy reduces radiocapitellar contact pressures while preserving valgus stability of the elbow},
  series = {Knee Surgery, Sports Traumatology, Arthroscopy},
  volume    = {25},
  journal   = {Knee Surgery, Sports Traumatology, Arthroscopy},
  number    = {7},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1433-7347},
  doi       = {10.1007/s00167-017-4468-z},
  pages     = {2280 -- 2288},
  year      = {2017},
  language  = {en}
}
@article{YoshinobuMiyamotoWerneretal.2017,
  author    = {Yoshinobu, Tatsuo and Miyamoto, Ko-ichiro and Werner, Frederik and Poghossian, Arshak and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Light-addressable potentiometric sensors for quantitative spatial imaging of chemical species},
  series = {Annual Review of Analytical Chemistry},
  volume    = {10},
  journal   = {Annual Review of Analytical Chemistry},
  publisher = {Annual Reviews},
  address   = {Palo Alto, Calif.},
  issn      = {1936-1327},
  doi       = {10.1146/annurev-anchem-061516-045158},
  pages     = {225 -- 246},
  year      = {2017},
  abstract  = {A light-addressable potentiometric sensor (LAPS) is a semiconductor-based chemical sensor, in which a measurement site on the sensing surface is defined by illumination. This light addressability can be applied to visualize the spatial distribution of pH or the concentration of a specific chemical species, with potential applications in the fields of chemistry, materials science, biology, and medicine. In this review, the features of this chemical imaging sensor technology are compared with those of other technologies. Instrumentation, principles of operation, and various measurement modes of chemical imaging sensor systems are described. The review discusses and summarizes state-of-the-art technologies, especially with regard to the spatial resolution and measurement speed; for example, a high spatial resolution in a submicron range and a readout speed in the range of several tens of thousands of pixels per second have been achieved with the LAPS. The possibility of combining this technology with microfluidic devices and other potential future developments are discussed.},
  language  = {en}
}
@article{BaeckerRakowskiKrappenetal.2017,
  author    = {B{\"a}cker, M. and Rakowski, D. and Krappen, E. and Sch{\"o}ning, Michael Josef},
  title     = {Reinigungsprozesse in der Lebensmittelindustrie. Entwicklung eines Demonstrators zur {\"U}berwachung},
  series = {GIT Labor-Fachzeitschrift},
  volume    = {61},
  journal   = {GIT Labor-Fachzeitschrift},
  number    = {8},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {0016-3538},
  pages     = {26 -- 28},
  year      = {2017},
  language  = {de}
}
@article{Dikta2017,
  author    = {Dikta, Gerhard},
  title     = {Semi-parametric random censorship models},
  series = {From Statistics to Mathematical Finance : Festschrift in Honour of Winfried Stute},
  journal   = {From Statistics to Mathematical Finance : Festschrift in Honour of Winfried Stute},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {978-3-319-50986-0},
  doi       = {10.1007/978-3-319-50986-0_3},
  pages     = {43 -- 56},
  year      = {2017},
  language  = {en}
}
@article{EngelmannBuhlBaumannetal.2017,
  author    = {Engelmann, Ulrich M. and Buhl, Eva Miriam and Baumann, Martin and Schmitz-Rode, Thomas and Slabu, Ioana},
  title     = {Agglomeration of magnetic nanoparticles and its effects on magnetic hyperthermia},
  series = {Current Directions in Biomedical Engineering},
  volume    = {3},
  journal   = {Current Directions in Biomedical Engineering},
  number    = {2},
  publisher = {De Gruyter},
  address   = {Berlin},
  issn      = {2364-5504},
  doi       = {10.1515/cdbme-2017-0096},
  pages     = {457 -- 460},
  year      = {2017},
  language  = {en}
}
@article{ChenJostVolkeretal.2017,
  author    = {Chen, Chao and Jost, Peter and Volker, Hanno and Kaminski, Marvin and Wirtssohn, Matti R. and Engelmann, Ulrich M. and Kr{\"u}ger, K. and Schlich, Franziska F. and Schlockermann, Carl and Lobo, Ricardo P.S.M. and Wuttig, Matthias},
  title     = {Dielectric properties of amorphous phase-change materials},
  series = {Physical Review B},
  volume    = {95},
  journal   = {Physical Review B},
  number    = {9},
  issn      = {2469-9950},
  doi       = {10.1103/PhysRevB.95.094111},
  pages     = {Article number 094111},
  year      = {2017},
  language  = {en}
}
@article{RoethSlabuEngelmannetal.2017,
  author    = {R{\"o}th, A.A. and Slabu, I. and Engelmann, Ulrich M. and Baumann, M. and Schmitz-Rode, T. and Neumann, U. P.},
  title     = {Targeting von gastroenterologischen Tumoren mittels magnetischer Nanopartikel zur hyperthermischen Therapie},
  series = {Zeitschrift f{\"u}r Gastroenterologie},
  volume    = {55},
  journal   = {Zeitschrift f{\"u}r Gastroenterologie},
  number    = {8},
  publisher = {Thieme},
  address   = {Stuttgart},
  doi       = {10.1055/s-0037-1605124},
  pages     = {KV-384},
  year      = {2017},
  language  = {de}
}
@inproceedings{SchreiberKraftZuendorf2017,
  author    = {Schreiber, Marc and Kraft, Bodo and Z{\"u}ndorf, Albert},
  title     = {Metrics Driven Research Collaboration: Focusing on Common Project Goals Continuously},
  series = {39th International Conference on Software Engineering, May 20-28, 2017 - Buenos Aires, Argentina},
  booktitle = {39th International Conference on Software Engineering, May 20-28, 2017 - Buenos Aires, Argentina},
  pages     = {8 Seiten},
  year      = {2017},
  abstract  = {Research collaborations provide opportunities for both practitioners and researchers: practitioners need solutions for difficult business challenges and researchers are looking for hard problems to solve and publish. Nevertheless, research collaborations carry the risk that practitioners focus on quick solutions too much and that researchers tackle theoretical problems, resulting in products which do not fulfill the project requirements. In this paper we introduce an approach extending the ideas of agile and lean software development. It helps practitioners and researchers keep track of their common research collaboration goal: a scientifically enriched software product which fulfills the needs of the practitioner's business model. This approach gives first-class status to application-oriented metrics that measure progress and success of a research collaboration continuously. Those metrics are derived from the collaboration requirements and help to focus on a commonly defined goal. An appropriate tool set evaluates and visualizes those metrics with minimal effort, and all participants will be pushed to focus on their tasks with appropriate effort. Thus project status, challenges and progress are transparent to all research collaboration members at any time.},
  language  = {en}
}
@article{SousaSiqueiraVerciketal.2017,
  author    = {Sousa, Marcos A. M. and Siqueira, Jose R. Jr. and Vercik, Andres and Sch{\"o}ning, Michael Josef and Oliveira, Osvaldo N. Jr.},
  title     = {Determining the optimized layer-by-layer film architecture with dendrimer/carbon nanotubes for field-effect sensors},
  series = {IEEE Sensors Journal},
  volume    = {17},
  journal   = {IEEE Sensors Journal},
  number    = {6},
  publisher = {IEEE},
  address   = {New York},
  issn      = {1558-1748},
  doi       = {10.1109/JSEN.2017.2653238},
  pages     = {1735 -- 1740},
  year      = {2017},
  abstract  = {The capacitive electrolyte-insulator-semiconductor (EIS) structure is a typical device based on a field-effect sensor platform. With a simple silicon-based structure, EIS have been useful for several sensing applications, especially with incorporation of nanostructured films to modulate the ionic transport and the flat-band potential. In this paper, we report on ion transport and changes in flat-band potential in EIS sensors made with layer-by-layer films containing poly(amidoamine) (PAMAM) dendrimer and single-walled carbon nanotubes (SWNTs) adsorbed on p-Si/SiO 2 /Ta 2 O 5 chips with an Al ohmic contact. The impedance spectra were fitted using an equivalent circuit model, from which we could determine parameters such as the double-layer capacitance. This capacitance decreased with the number of bilayers owing to space charge accumulated at the electrolyte-insulator interface, up to three PAMAM/SWNTs bilayers, after which it stabilized. The charge-transfer resistance was also minimum for three bilayers, thus indicating that this is the ideal architecture for an optimized EIS performance. The understanding of the influence of nanostructures and the fine control of operation parameters pave the way for optimizing the design and performance of new EIS sensors.},
  language  = {en}
}
@article{ArreolaOberlaenderMaetzkowetal.2017,
  author    = {Arreola, Julio and Oberl{\"a}nder, Jan and M{\"a}tzkow, M. and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Surface functionalization for spore-based biosensors with organosilanes},
  series = {Electrochimica Acta},
  volume    = {241},
  journal   = {Electrochimica Acta},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0013-4686},
  doi       = {10.1016/j.electacta.2017.04.157},
  pages     = {237 -- 243},
  year      = {2017},
  abstract  = {In the present work, surface functionalization of different sensor materials was studied. Organosilanes are well known to serve as coupling agent for biomolecules or cells on inorganic materials. 3-aminopropyltriethoxysilane (APTES) was used to attach microbiological spores time to an interdigitated sensor surface. The functionality and physical properties of APTES were studied on isolated sensor materials, namely silicon dioxide (SiO2) and platinum (Pt) as well as the combined material on sensor level. A predominant immobilization of spores could be demonstrated on SiO2 surfaces. Additionally, the impedance signal of APTES-functionalized biosensor chips has been investigated.},
  language  = {en}
}
@inproceedings{SchmidtsBoltesKraftetal.2017,
  author    = {Schmidts, Oliver and Boltes, Maik and Kraft, Bodo and Schreiber, Marc},
  title     = {Multi-pedestrian tracking by moving Bluetooth-LE beacons and stationary receivers},
  series = {2017 International Conference on Indoor Positioning and Indoor Navigation (IPIN), 18-21 September 2017, Sapporo, Japan},
  booktitle = {2017 International Conference on Indoor Positioning and Indoor Navigation (IPIN), 18-21 September 2017, Sapporo, Japan},
  pages     = {1 -- 4},
  year      = {2017},
  language  = {en}
}
@article{DantismTakenagaWagneretal.2017,
  author    = {Dantism, Shahriar and Takenaga, Shoko and Wagner, Torsten and Wagner, Patrick and Sch{\"o}ning, Michael Josef},
  title     = {Differential imaging of the metabolism of bacteria and eukaryotic cells based on light-addressable potentiometric sensors},
  series = {Electrochimica Acta},
  volume    = {246},
  journal   = {Electrochimica Acta},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0013-4686},
  doi       = {10.1016/j.electacta.2017.05.196},
  pages     = {234 -- 241},
  year      = {2017},
  abstract  = {A light-addressable potentiometric sensor (LAPS) is a field-effect-based potentiometric sensor with an electrolyte/insulator/semiconductor (EIS) structure, which is able to monitor analyte concentrations of (bio-)chemical species in aqueous solutions in a spatially resolved way. Therefore, it is also an appropriate tool to record 2D-chemical images of concentration variations on the sensor surface. In the present work, two differential, LAPS-based measurement principles are introduced to determine the metabolic activity of Escherichia coli (E. coli) K12 and Chinese hamster ovary (CHO) cells as test microorganisms. Hereby, we focus on i) the determination of the extracellular acidification rate (ΔpH/min) after adding glucose solutions to the cell suspensions; and ii) recording the amplitude increase of the photocurrent (Iph) related to the produced acids from E. coli K12 bacteria and CHO cells on the sensor surface by 2D-chemical imaging. For this purpose, 3D-printed multi-chamber structures were developed and mounted on the planar sensor-chip surface to define four independent compartments, enabling differential measurements with varying cell concentrations. The differential concept allows eliminating unwanted drift effects and, with the four-chamber structures, measurements on the different cell concentrations were performed simultaneously, thus reducing also the overall measuring time.},
  language  = {en}
}
@article{JildehKirchnerOberlaenderetal.2017,
  author    = {Jildeh, Zaid B. and Kirchner, Patrick and Oberl{\"a}nder, Jan and Kremers, Alexander and Wagner, Torsten and Wagner, Patrick H. and Sch{\"o}ning, Michael Josef},
  title     = {FEM-based modeling of a calorimetric gas sensor for hydrogen peroxide monitoring},
  series = {physica status solidi a : applications and materials sciences},
  journal   = {physica status solidi a : applications and materials sciences},
  number    = {Early View},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201600912},
  year      = {2017},
  abstract  = {A physically coupled finite element method (FEM) model is developed to study the response behavior of a calorimetric gas sensor. The modeled sensor serves as a monitoring device of the concentration of gaseous hydrogen peroxide (H2 O2) in a high temperature mixture stream in aseptic sterilization processes. The principle of operation of a calorimetric H2 O2 sensor is analyzed and the results of the numerical model have been validated by using previously published sensor experiments. The deviation in the results between the FEM model and experimental data are presented and discussed.},
  language  = {en}
}
@article{ArreolaKeusgenSchoening2017,
  author    = {Arreola, Julio and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Effect of O2 plasma on properties of electrolyte-insulator-semiconductor structures},
  series = {physica status solidi a : applications and materials sciences},
  volume    = {214},
  journal   = {physica status solidi a : applications and materials sciences},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201700025},
  pages     = {Artikel 1700025},
  year      = {2017},
  abstract  = {Prior to immobilization of biomolecules or cells onto biosensor surfaces, the surface must be physically or chemically activated for further functionalization. Organosilanes are a versatile option as they facilitate the immobilization through their terminal groups and also display self-assembly. Incorporating hydroxyl groups is one of the important methods for primary immobilization. This can be done, for example, with oxygen plasma treatment. However, this treatment can affect the performance of the biosensors and this effect is not quite well understood for surface functionalization. In this work, the effect of O2 plasma treatment on EIS sensors was investigated by means of electrochemical characterizations: capacitance-voltage (C-V) and constant capacitance (ConCap) measurements. After O2 plasma treatment, the potential of the EIS sensor dramatically shifts to a more negative value. This was successfully reset by using an annealing process.},
  language  = {en}
}