@masterthesis{Breuer2024,
  type      = {Bachelor Thesis},
  author    = {Breuer, Annika},
  title     = {Climate Engineering : Entwicklung einer digitalen Plattform f{\"u}r Geoengineering-Methoden und Klimawandel-Daten},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {71 Seiten},
  year      = {2024},
  abstract  = {Dieses Projekt hat zum Ziel, umfassend {\"u}ber Climate Engineering-Maßnahmen zu informieren und dabei insbesondere ihre Funktionsweise, Kosten und Risiken darzustellen. Die entstandene Plattform "Die Erde abk{\"u}hlen!" bietet einen Einblick in die L{\"o}sungsans{\"a}tze des Climate Engineerings durch die Verwendung von Storytelling. Sie erm{\"o}glicht Nutzer:innen einen {\"U}berblick {\"u}ber den aktuellen Stand der Klimaerw{\"a}rmung sowie den Vergleich von Climate Engineering-Maßnahmen. Ein entwickeltes Bewertungssystem auf Grundlage der "Royal Society" sowie interaktive Infografiken geben Nutzer:innen einen umfassenden Einblick. Das Hauptziel des Projekts ist die digitale Transformation der Climate Engineering-L{\"o}sungsans{\"a}tze. Dabei geht es nicht nur darum, {\"u}ber die Folgen der Klimaerw{\"a}rmung zu informieren, sondern auch konkrete L{\"o}sungen aufzuzeigen. Durch die Entwicklung eines innovativen Storytellings wird die Thematik nicht nur dramaturgisch pr{\"a}sentiert, sondern erm{\"o}glicht es den Nutzer:innen auch, ihre eigene Wissensvertiefung zu steuern.},
  language  = {de}
}
@masterthesis{Darboven2024,
  type      = {Bachelor Thesis},
  author    = {Darboven, Mona},
  title     = {Gamifizierte Online-Schulung zur IT-Sicherheit : Konzeption \& Gestaltung verschiedener Ans{\"a}tze},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {140 Seiten},
  year      = {2024},
  abstract  = {Das Ziel der webbasierten, gamifizierten Schulung ist die Awareness der IT-Sicherheit f{\"u}r Studierende. Das Verhalten der Studierenden soll nachhaltig ge{\"a}ndert werden, damit zuk{\"u}nftige Cyberangriffe weniger wirksam werden. Im Mittelpunkt steht ein spannendes und motivierendes Konzept auf den Grundlagen des Game Based Learnings, das z. B. mit Interactives arbeitet. Zur St{\"a}rkung des Risiko-Bewusstseins wurde eine Roadmap entwickelt, die wie ein Spielbrett Zusammenh{\"a}nge, aber auch den Fortschritt der Schulung aufzeigt. So entstand zun{\"a}chst in interdisziplin{\"a}rer Zusammenarbeit mit einer Wirtschaftsinformatik-Studentin ein technischer Prototyp. Darauf aufbauend wurden weitere konzeptionelle und visuelle Ans{\"a}tze entwickelt, die das breite Spektrum von Game Based Learning zeigen. Dieses realit{\"a}tsnahe Projekt zeigt zukunftsweisende Lernumgebungen auf.},
  language  = {de}
}
@masterthesis{Frings2024,
  type      = {Bachelor Thesis},
  author    = {Frings, Christina},
  title     = {Unerw{\"u}nscht : Anti-Gestaltung im {\"o}ffentlichen Raum},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {55 Seiten},
  year      = {2024},
  abstract  = {»Unerw{\"u}nscht« widmet sich einer Art von architektonischer Gestaltung, die auf t{\"u}ckische Weise als »defensive Architektur« bezeichnet wird. In Form einer Zeitung bietet sie einen umfassenden Einblick in das Thema und gew{\"a}hrt einen vielseitigen Blick in eine Thematik, die im Interesse der Verantwortlichen lieber im Verborgenen geblieben w{\"a}re. Defensive Architektur bezeichnet strategische Baumaßnahmen in der Stadt- und Bauplanung, die darauf abzielen, unerw{\"u}nschte Personengruppen durch unpraktisches oder unbequemes Design von bestimmten Orten fernzuhalten. Diese Maßnahmen richten sich beispielsweise gegen obdachlose Menschen, Jugendliche oder Skateboarder*innen. Die {\"u}berwiegende Mehrheit der Bev{\"o}lkerung ist sich weder der Existenz von solchen architektonischen Maßnahmen noch ihrer Auswirkungen auf das Leben der Betroffenen bewusst. »Unerw{\"u}nscht« zielt darauf ab, diese L{\"u}cke in der {\"o}ffentlichen Wahrnehmung zu schließen.},
  language  = {de}
}
@masterthesis{Lambertus2024,
  type      = {Bachelor Thesis},
  author    = {Lambertus, Jan-Michael},
  title     = {CardboardCastle},
  publisher = {FH Aachen},
  address   = {Aachen},
  school      = {Fachhochschule Aachen},
  pages     = {60 Seiten},
  year      = {2024},
  abstract  = {„CardboardCastle" ist ein 3D-Animationsfilm. Der Film zeigt die lebendig gewordene Welt zweier K{\"o}nigreiche aus Pappe, die in einem Streit um einen magischen Zauberstab verwickelt sind. Das Projekt beweist, dass es m{\"o}glich ist, mit der Software „Blender" einen vollwertigen und hochwertigen 3D-Animationsfilm zu erstellen. Dabei wurden alle Assets bis auf Texturen selbst hergestellt. Die virtuelle Pappe spielt hierbei eine fundamentale Rolle, f{\"u}r diese wurde ein vollkommen neuer Workflow entwickelt, welcher es erm{\"o}glicht, realistische Pappe zu visualisieren. „CardboardCastle" setzt auf eine cinematische Inszenierung von Licht und vereint technisches Wissen mit unterhaltenden Inhalten. Dabei zeigt er die kindliche Vorstellungskraft und l{\"a}dt die Zuschauer ein, sich an ihre eigenen kindlichen Fantasien zu erinnern.},
  language  = {de}
}
@article{HaegerJolmesOyenetal.2024,
  author    = {Haeger, Gerrit and Jolmes, Tristan and Oyen, Sven and Jaeger, Karl-Erich and Bongaerts, Johannes and Sch{\"o}rken, Ulrich and Siegert, Petra},
  title     = {Novel recombinant aminoacylase from Paraburkholderia monticola capable of N-acyl-amino acid synthesis},
  series = {Applied Microbiology and Biotechnology},
  journal   = {Applied Microbiology and Biotechnology},
  number    = {108},
  publisher = {Springer},
  address   = {Berlin},
  issn      = {1432-0614},
  doi       = {10.1007/s00253-023-12868-8},
  pages     = {14 Seiten},
  year      = {2024},
  abstract  = {N-Acyl-amino acids can act as mild biobased surfactants, which are used, e.g., in baby shampoos. However, their chemical synthesis needs acyl chlorides and does not meet sustainability criteria. Thus, the identification of biocatalysts to develop greener synthesis routes is desirable. We describe a novel aminoacylase from Paraburkholderia monticola DSM 100849 (PmAcy) which was identified, cloned, and evaluated for its N-acyl-amino acid synthesis potential. Soluble protein was obtained by expression in lactose autoinduction medium and co-expression of molecular chaperones GroEL/S. Strep-tag affinity purification enriched the enzyme 16-fold and yielded 15 mg pure enzyme from 100 mL of culture. Biochemical characterization revealed that PmAcy possesses beneficial traits for industrial application like high temperature and pH-stability. A heat activation of PmAcy was observed upon incubation at temperatures up to 80 °C. Hydrolytic activity of PmAcy was detected with several N-acyl-amino acids as substrates and exhibited the highest conversion rate of 773 U/mg with N-lauroyl-L-alanine at 75 °C. The enzyme preferred long-chain acyl-amino-acids and displayed hardly any activity with acetyl-amino acids. PmAcy was also capable of N-acyl-amino acid synthesis with good conversion rates. The best synthesis results were obtained with the cationic L-amino acids L-arginine and L-lysine as well as with L-leucine and L-phenylalanine. Exemplarily, L-phenylalanine was acylated with fatty acids of chain lengths from C8 to C18 with conversion rates of up to 75\%. N-lauroyl-L-phenylalanine was purified by precipitation, and the structure of the reaction product was verified by LC-MS and NMR.},
  language  = {en}
}
@article{KochBoehnischVerdoncketal.2024,
  author    = {Koch, Christopher and B{\"o}hnisch, Nils and Verdonck, Hendrik and Hach, Oliver and Braun, Carsten},
  title     = {Comparison of unsteady low- and mid-fidelity propeller aerodynamic methods for whirl flutter applications},
  series = {Applied Sciences},
  volume    = {14},
  journal   = {Applied Sciences},
  number    = {2},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2076-3417},
  doi       = {10.3390/app14020850},
  pages     = {1 -- 28},
  year      = {2024},
  abstract  = {Aircraft configurations with propellers have been drawing more attention in recent times, partly due to new propulsion concepts based on hydrogen fuel cells and electric motors. These configurations are prone to whirl flutter, which is an aeroelastic instability affecting airframes with elastically supported propellers. It commonly needs to be mitigated already during the design phase of such configurations, requiring, among other things, unsteady aerodynamic transfer functions for the propeller. However, no comprehensive assessment of unsteady propeller aerodynamics for aeroelastic analysis is available in the literature. This paper provides a detailed comparison of nine different low- to mid-fidelity aerodynamic methods, demonstrating their impact on linear, unsteady aerodynamics, as well as whirl flutter stability prediction. Quasi-steady and unsteady methods for blade lift with or without coupling to blade element momentum theory are evaluated and compared to mid-fidelity potential flow solvers (UPM and DUST) and classical, derivative-based methods. Time-domain identification of frequency-domain transfer functions for the unsteady propeller hub loads is used to compare the different methods. Predictions of the minimum required pylon stiffness for stability show good agreement among the mid-fidelity methods. The differences in the stability predictions for the low-fidelity methods are higher. Most methods studied yield a more unstable system than classical, derivative-based whirl flutter analysis, indicating that the use of more sophisticated aerodynamic modeling techniques might be required for accurate whirl flutter prediction.},
  language  = {en}
}
@book{StaatDigelTrzewiketal.2024,
  author    = {Staat, Manfred and Digel, Ilya and Trzewik, J{\"u}rgen and Sielemann, Stefanie and Erni, Daniel and Zylka, Waldemar},
  title     = {Symposium Proceedings; 4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-65-3},
  doi       = {10.17185/duepublico/81475},
  pages     = {40 Seiten},
  year      = {2024},
  language  = {en}
}
@inproceedings{SimsekKrauseEngelmann2024,
  author    = {Simsek, Beril and Krause, Hans-Joachim and Engelmann, Ulrich M.},
  title     = {Magnetic biosensing with magnetic nanoparticles: Simulative approach to predict signal intensity in frequency mixing magnetic detection},
  series = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen},
  booktitle = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen},
  editor    = {Digel, Ilya and Staat, Manfred and Trzewik, J{\"u}rgen and Sielemann, Stefanie and Erni, Daniel and Zylka, Waldemar},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-65-3},
  doi       = {10.17185/duepublico/81475},
  pages     = {27 -- 28},
  year      = {2024},
  abstract  = {Magnetic nanoparticles (MNP) are investigated with great interest for biomedical applications in diagnostics (e.g. imaging: magnetic particle imaging (MPI)), therapeutics (e.g. hyperthermia: magnetic fluid hyperthermia (MFH)) and multi-purpose biosensing (e.g. magnetic immunoassays (MIA)). What all of these applications have in common is that they are based on the unique magnetic relaxation mechanisms of MNP in an alternating magnetic field (AMF). While MFH and MPI are currently the most prominent examples of biomedical applications, here we present results on the relatively new biosensing application of frequency mixing magnetic detection (FMMD) from a simulation perspective. In general, we ask how the key parameters of MNP (core size and magnetic anisotropy) affect the FMMD signal: by varying the core size, we investigate the effect of the magnetic volume per MNP; and by changing the effective magnetic anisotropy, we study the MNPs' flexibility to leave its preferred magnetization direction. From this, we predict the most effective combination of MNP core size and magnetic anisotropy for maximum signal generation.},
  language  = {en}
}
@inproceedings{SchmitzApandiSpillneretal.2024,
  author    = {Schmitz, Annika and Apandi, Shah Eiman Amzar Shah and Spillner, Jan and Hima, Flutura and Behbahani, Mehdi},
  title     = {Effect of different cannula positions in the pulmonary artery on blood flow and gas exchange using computational fluid dynamics analysis},
  series = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen},
  booktitle = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen},
  editor    = {Digel, Ilya and Staat, Manfred and Trzewik, J{\"u}rgen and Sielemann, Stefanie and Erni, Daniel and Zylka, Waldemar},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-65-3},
  doi       = {10.17185/duepublico/81475},
  pages     = {29 -- 30},
  year      = {2024},
  abstract  = {Pulmonary arterial cannulation is a common and effective method for percutaneous mechanical circulatory support for concurrent right heart and respiratory failure [1]. However, limited data exists to what effect the positioning of the cannula has on the oxygen perfusion throughout the pulmonary artery (PA). This study aims to evaluate, using computational fluid dynamics (CFD), the effect of different cannula positions in the PA with respect to the oxygenation of the different branching vessels in order for an optimal cannula position to be determined. The four chosen different positions (see Fig. 1) of the cannulas are, in the lower part of the main pulmonary artery (MPA), in the MPA at the junction between the right pulmonary artery (RPA) and the left pulmonary artery (LPA), in the RPA at the first branch of the RPA and in the LPA at the first branch of the LPA.},
  language  = {en}
}
@inproceedings{SherelkhanAlibekova2024,
  author    = {Sherelkhan, Dinara and Alibekova, Alina},
  title     = {EEM spectroscopy characterization of humic substances of biomedical importance},
  series = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen},
  booktitle = {4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen},
  editor    = {Digel, Ilya and Staat, Manfred and Trzewik, J{\"u}rgen and Sielemann, Stefanie and Erni, Daniel and Zylka, Waldemar},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-65-3},
  doi       = {10.17185/duepublico/81475},
  pages     = {31 -- 32},
  year      = {2024},
  abstract  = {Humic substances possess distinctive chemical features enabling their use in many advanced applications, including biomedical fields. No chemicals in nature have the same combination of specific chemical and biological properties as humic substances. Traditional medicine and modern research have demonstrated that humic substances from different sources possess immunomodulatory and anti-inflammatory properties, which makes them suitable for the prevention and treatment of chronic dermatoses, allergic rhinitis, atopic dermatitis, and other conditions characterized by inflammatory and allergic responses [1-4]. The use of humic compounds as agentswith antifungal and antiviral properties shows great potential [5-7].},
  language  = {en}
}