@article{MangKricheldorfJonte1985, author = {Mang, Thomas and Kricheldorf, Hans R. and Jont{\´e}, J. Michael}, title = {Polylactones, 2. Copolymerization of glycolide with \&\#946;-propiolactone, \&\#967;-butyrolactone or \&\#948;-valerolactone / Kricheldorf, Hans R. ; Mang, Thomas ; Jont{\´e}, J. Michael}, series = {Die makromolekulare Chemie. 186 (1985), H. 5}, journal = {Die makromolekulare Chemie. 186 (1985), H. 5}, isbn = {1022-1352}, pages = {955 -- 976}, year = {1985}, language = {en} } @article{MangKricheldorfJonte1984, author = {Mang, Thomas and Kricheldorf, Hans R. and Jont{\´e}, J. Michael}, title = {Polylactones. 1. Copolymerizations of glycolide and \&beta-caprolactone / Kricheldorf, Hans R. ; Mang, Thomas ; Jont{\´e}, J. Michael}, series = {Macromolecules. 17 (1984), H. 10}, journal = {Macromolecules. 17 (1984), H. 10}, isbn = {0024-9297}, pages = {2173 -- 2181}, year = {1984}, language = {en} } @article{Mang2004, author = {Mang, Thomas}, title = {Polymer Magnetic Particles for Isolating Biomolecules, Especially Nucleic Acids}, series = {Biomedizinische Technik = Biomedical Engineering. 49 (2004), H. 2}, journal = {Biomedizinische Technik = Biomedical Engineering. 49 (2004), H. 2}, isbn = {0013-5585}, pages = {1008 -- 1009}, year = {2004}, language = {en} } @article{SchererHoerHertel1998, author = {Scherer, Ulrich W. and H{\"o}r, G. and Hertel, A.}, title = {Positronen-Emissions-Tomographie des Herzens / G. H{\"o}r, A. Hertel, U. W. Scherer}, series = {Herzerkrankungen und Interventionsm{\"o}glichkeiten / F. Unger [Hrsg.]}, journal = {Herzerkrankungen und Interventionsm{\"o}glichkeiten / F. Unger [Hrsg.]}, publisher = {Springer}, address = {Berlin}, isbn = {3-540-62916-5}, pages = {236 -- 263}, year = {1998}, language = {de} } @article{OosterhuisOehlschlaegerBergetal.2011, author = {Oosterhuis, Koen and {\"O}hlschl{\"a}ger, Peter and Berg, Joost H. van den and Toebes, Mireille and Gomez, Raquel and Schumacher, Ton N. and Haanen, John B.}, title = {Preclinical development of highly effective and safe DNA vaccines directed against HPV 16 E6 and E7}, series = {International Journal of Cancer}, volume = {129}, journal = {International Journal of Cancer}, number = {2}, publisher = {Wiley}, address = {Weinheim}, isbn = {1097-0215}, pages = {397 -- 406}, year = {2011}, language = {en} } @article{HenkenOosterhuisOehlschlaegeretal.2012, author = {Henken, F. E. and Oosterhuis, K. and {\"O}hlschl{\"a}ger, Peter and Bosch, L. and Hooijberg, E. and Haanen, J. B. A. G. and Steenbergen, R. D. M.}, title = {Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7}, series = {Vaccine}, volume = {30}, journal = {Vaccine}, number = {28}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0264-410X}, doi = {10.1016/j.vaccine.2012.04.013}, pages = {4259 -- 4266}, year = {2012}, abstract = {Persistent infection with high-risk human papillomaviruses (hrHPV) can result in the formation of anogenital cancers. As hrHPV proteins E6 and E7 are required for cancer initiation and maintenance, they are ideal targets for immunotherapeutic interventions. Previously, we have described the development of DNA vaccines for the induction of HPV16 E6 and E7 specific T cell immunity. These vaccines consist of 'gene-shuffled' (SH) versions of HPV16 E6 and E7 that were fused to Tetanus Toxin Fragment C domain 1 (TTFC) and were named TTFC-E6SH and TTFC-E7SH. Gene-shuffling was performed to avoid the risk of inducing malignant transformation at the vaccination site. Here, we describe the preclinical safety evaluation of these candidate vaccines by analysis of their transforming capacity in vitro using established murine fibroblasts (NIH 3T3 cells) and primary human foreskin keratinocytes (HFKs). We demonstrate that neither ectopic expression of TTFC-E6SH and TTFC-E7SH alone or in combination enabled NIH 3T3 cells to form colonies in soft agar. In contrast, expression of HPV16 E6WT and E7WT alone or in combination resulted in effective transformation. Similarly, retroviral transduction of HFKs from three independent donors with both TTFC-E6SH and TTFC-E7SH alone or in combination did not show any signs of immortalization. In contrast, the combined expression of E6WT and E7WT induced immortalization in HFKs from all donors. Based on these results we consider it justified to proceed to clinical evaluation of DNA vaccines encoding TTFC-E6SH and TTFC-E7SH in patients with HPV16 associated (pre)malignancies.}, language = {en} } @article{BiselliSchmidWandrey1988, author = {Biselli, Manfred and Schmid, Georg and Wandrey, Christian}, title = {Preparation of cellodextrins and isolation of oligomeric side components and their characterization / Schmid, Georg ; Biselli, Manfred ; Wandrey, Christian}, series = {Analytical Biochemistry. 175 (1988)}, journal = {Analytical Biochemistry. 175 (1988)}, isbn = {0003-2697}, pages = {573 -- 583}, year = {1988}, language = {en} } @article{KotterHammon1986, author = {Kotter, Michael and Hammon, U.}, title = {Preparation of pellets with well-defined pore structure / U. Hammon ; A. Kotter}, series = {International chemical engineering. 26 (1986), H. 4}, journal = {International chemical engineering. 26 (1986), H. 4}, isbn = {0020-6318}, pages = {563 -- 573}, year = {1986}, language = {en} } @article{NaithaniKlostermeyerLangeetal.1971, author = {Naithani, V. K and Klostermeyer, Henning and Lange, H. R. and [u.a.], and Berndt, Heinz and [u.a.],}, title = {Preparation of peptide derivatives for porcine proinsulin-synthesis}, series = {Biological Chemistry}, volume = {352}, journal = {Biological Chemistry}, number = {1}, publisher = {De Gruyter}, issn = {1437-4315}, doi = {10.1515/bchm2.1971.352.1.1}, pages = {2 -- 3}, year = {1971}, language = {en} } @article{PrielmeierWoznyjLuedemann1984, author = {Prielmeier, Franz and Woznyj, M. and L{\"u}demann, H.-D.}, title = {Pressure Dependence of the Melting and Self Diffusion in 2,2-Dimethylpropane, 2,2-Dimethylpropionitrile, and 2-Methylpropanol-2 / M. Woznyj, F. X. Prielmeier, H.-D. L{\"u}demann}, series = {Zeitschrift f{\"u}r Naturforschung A, Journal of Physical Sciences. 39 (1984)}, journal = {Zeitschrift f{\"u}r Naturforschung A, Journal of Physical Sciences. 39 (1984)}, isbn = {0932-0784}, pages = {800}, year = {1984}, language = {en} } @article{PrielmeierLangLuedemann1984, author = {Prielmeier, Franz and Lang, E. W. and L{\"u}demann, H.-D.}, title = {Pressure dependence of the self-diffusion in liquid trifluoromethane / F. X. Prielmeier; E. W. Lang; H.-D. L{\"u}demann}, series = {Molecular Physics. 52 (1984), H. 5}, journal = {Molecular Physics. 52 (1984), H. 5}, isbn = {0026-8976}, pages = {1105 -- 1113}, year = {1984}, language = {en} } @article{KotterRiekertSimoncic1986, author = {Kotter, Michael and Riekert, Lothar and Simoncic, V.}, title = {Pristup sintezi industrijskih katalizatora}, series = {Kemija u industriji : casopis kemicara i tehnologa Jugoslavije. 35 (1986)}, journal = {Kemija u industriji : casopis kemicara i tehnologa Jugoslavije. 35 (1986)}, isbn = {0022-9830}, pages = {79 -- 86}, year = {1986}, language = {de} } @article{ElbersMuratyan1991, author = {Elbers, Gereon and Muratyan, Simone}, title = {Problematik verkehrsbezogener Außenluftmessungen von Partikeln (Dieselruß)}, series = {+ Krebserzeugende Stoffe in der Umwelt : Herkunft, Messung, Risiko, Minimierung ; Kolloquium Mannheim, 23. bis 25. April 1991 / Kommission Reinhaltung der Luft im VDI und DIN}, journal = {+ Krebserzeugende Stoffe in der Umwelt : Herkunft, Messung, Risiko, Minimierung ; Kolloquium Mannheim, 23. bis 25. April 1991 / Kommission Reinhaltung der Luft im VDI und DIN}, publisher = {VDI-Verl.}, address = {D{\"u}sseldorf}, isbn = {3-18-090888-2}, pages = {143}, year = {1991}, language = {de} } @article{TuegBaumann1994, author = {T{\"u}g, Helmut and Baumann, Marcus}, title = {Problems of UV-B radiation measurements in biological research : critical remarks on current techniques and suggestions for improvements}, series = {Geophysical research letters}, volume = {Vol. 21}, journal = {Geophysical research letters}, number = {Iss. 8}, issn = {1944-8007 (E-Journal); 0094-8276 (Print)}, pages = {689 -- 692}, year = {1994}, language = {en} } @article{GerigkBujnickiGanpoNkwenkwaetal.2002, author = {Gerigk, M. and Bujnicki, R. and Ganpo-Nkwenkwa, E. and Bongaerts, Johannes and Sprenger, G. and Takors, Ralf}, title = {Process control for enhanced L-phenylalanine production using different recombinant Escherichia coli strains}, series = {Biotechnology and bioengineering}, volume = {Vol. 80}, journal = {Biotechnology and bioengineering}, number = {Iss. 7}, issn = {1097-0290 (E-Journal); 0006-3592 (Print)}, pages = {746 -- 754}, year = {2002}, language = {en} } @article{MuesgenanntKoersMcNeilRadchenkoetal.2023, author = {Mues genannt Koers, Lucas and McNeil, S. W. and Radchenko, V. and Paulßen, Elisabeth and Hoehr, Cornelia}, title = {Production of Co-58m in a siphon-style liquid target on a medical cyclotron}, volume = {195}, number = {Art. 110734}, publisher = {Elsevier}, address = {Amsterdam}, issn = {0969-8043}, doi = {10.1016/j.apradiso.2023.110734}, year = {2023}, abstract = {We present the production of 58mCo on a small, 13 MeV medical cyclotron utilizing a siphon style liquid target system. Different concentrated iron(III)-nitrate solutions of natural isotopic distribution were irradiated at varying initial pressures and subsequently separated by solid phase extraction chromatography. The radio cobalt (58m/gCo and 56Co) was successfully produced with saturation activities of (0.35 ± 0.03) MBq μA-1 for 58mCo with a separation recovery of (75 ± 2) \% of cobalt after one separation step utilizing LN-resin.}, language = {en} } @article{BiselliBornWandrey1995, author = {Biselli, Manfred and Born, C. and Wandrey, C.}, title = {Production of monoclonal antibodies in a pilot scale fluidized bed bioreactor / Born, C.; Biselli, M.; Wandrey, C.}, series = {Animal cell technology : developments towards the 21st century / edited by E. C. Beuvery}, journal = {Animal cell technology : developments towards the 21st century / edited by E. C. Beuvery}, publisher = {Kluwer Acad. Press}, address = {Dordrecht}, isbn = {0-7923-3736-0}, pages = {515 -- 519}, year = {1995}, language = {en} } @article{PaulssenHoehrHouetal.2015, author = {Paulßen, Elisabeth and Hoehr, Cornelia and Hou, Xinchi and Hanemaayer, Victoire and Zeisler, Stefan and Adam, Michael J. and Ruth, Thomas J. and Celler, Anna and Buckley, Ken and Benard, Francois and Schaffer, Paul}, title = {Production of Y-86 and other radiometals for research purposes using a solution target system}, series = {Nuclear medicine and biology}, volume = {42}, journal = {Nuclear medicine and biology}, number = {11}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1872-9614}, doi = {10.1016/j.nucmedbio.2015.06.005}, pages = {842 -- 849}, year = {2015}, language = {en} } @article{SelmerAchebachUnden2005, author = {Selmer, Thorsten and Achebach, Stephanie and Unden, Gottfried}, title = {Properties and significance of apoFNR as a second form of air-inactivated [4Fe-4S]·FNR of Escherichia coli / Achebach, S. ; Selmer, T. ; Unden, G.}, series = {The FEBS Journal. 272 (2005), H. 16}, journal = {The FEBS Journal. 272 (2005), H. 16}, isbn = {1742-464X}, pages = {4260 -- 4269}, year = {2005}, language = {en} } @article{SelmerWillanzheimerHetzel2002, author = {Selmer, Thorsten and Willanzheimer, Angela and Hetzel, Marc}, title = {Propionate CoA-transferase from Clostridium propionicum. Cloning of the gene and identification of glutamate 324 at the active site}, series = {European Journal of Biochemistry. 269 (2002), H. 1}, journal = {European Journal of Biochemistry. 269 (2002), H. 1}, isbn = {0014-2956}, pages = {372 -- 380}, year = {2002}, language = {en} }