@article{KurulganDemirciDemirciLinderetal.2012,
  author    = {Kurulgan Demirci, Eylem and Demirci, Taylan and Linder, Peter and Trzewik, J{\"u}rgen and Gierkowski, Jessica Ricarda and Gossmann, Matthias and Kayser, Peter and Porst, Dariusz and Digel, Ilya and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {rhAPC reduces the endothelial cell permeability via a decrease of contractile tensions induced by endothelial cells},
  series = {Journal of Bioscience and Bioengineering},
  volume    = {113},
  journal   = {Journal of Bioscience and Bioengineering},
  number    = {2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1347-4421},
  doi       = {10.1016/j.jbiosc.2012.03.019},
  pages     = {212 -- 219},
  year      = {2012},
  abstract  = {All cells generate contractile tension. This strain is crucial for mechanically controlling the cell shape, function and survival. In this study, the CellDrum technology quantifying cell's (the cellular) mechanical tension on a pico-scale was used to investigate the effect of lipopolysaccharide (LPS) on human aortic endothelial cell (HAoEC) tension. The LPS effect during gram-negative sepsis on endothelial cells is cell contraction causing endothelium permeability increase. The aim was to finding out whether recombinant activated protein C (rhAPC) would reverse the endothelial cell response in an in-vitro sepsis model. In this study, the established in-vitro sepsis model was confirmed by interleukin 6 (IL-6) levels at the proteomic and genomic levels by ELISA, real time-PCR and reactive oxygen species (ROS) activation by florescence staining. The thrombin cellular contraction effect on endothelial cells was used as a positive control when the CellDrum technology was applied. Additionally, the Ras homolog gene family, member A (RhoA) mRNA expression level was checked by real time-PCR to support contractile tension results. According to contractile tension results, the mechanical predominance of actin stress fibers was a reason of the increased endothelial contractile tension leading to enhanced endothelium contractility and thus permeability enhancement. The originality of this data supports firstly the basic measurement principles of the CellDrum technology and secondly that rhAPC has a beneficial effect on sepsis influenced cellular tension. The technology presented here is promising for future high-throughput cellular tension analysis that will help identify pathological contractile tension responses of cells and prove further cell in-vitro models.},
  language  = {en}
}
@article{HanssenNickelDrexeletal.2011,
  author    = {Hanssen, H. and Nickel, T. and Drexel, V. and Hertel, G. and Emslander, I. and Sisic, Z. and Lorang, D. and Schuster, T. and Kotliar, Konstantin and Pressler, A. and Schmidt-Trucks{\"a}ss, A. and Weis, M. and Halle, M.},
  title     = {Exercise-induced alterations of retinal vessel diameters and cardiovascular risk reduction in obesity},
  series = {Atherosclerosis},
  volume    = {216},
  journal   = {Atherosclerosis},
  number    = {2},
  publisher = {Elsevier},
  address   = {Amsterdam},
  isbn      = {0021-9150},
  pages     = {433 -- 439},
  year      = {2011},
  language  = {en}
}
@article{StaatTrenzLohmannetal.2012,
  author    = {Staat, Manfred and Trenz, Eva and Lohmann, Philipp and Frotscher, Ralf and Klinge, Uwe and Tabaza, Ruth and Kirschner-Hermanns, Ruth},
  title     = {New measurements to compare soft tissue anchoring systems in pelvic floor surgery},
  series = {Journal of Biomedical Materials Research Part B: Applied Biomaterials},
  volume    = {100B},
  journal   = {Journal of Biomedical Materials Research Part B: Applied Biomaterials},
  number    = {4},
  publisher = {Wiley},
  address   = {Hoboken, NJ},
  issn      = {1552-4981},
  doi       = {10.1002/jbm.b.32654},
  pages     = {924 -- 933},
  year      = {2012},
  abstract  = {Suburethral slings as well as different meshes are widely used treating stress urinary incontinence and prolaps in women. With the development of MiniSlings and special meshes using less alloplastic material anchorage systems become more important to keep devices in place and to put some tension especially on the MiniSlings. To date, there are many different systems of MiniSlings of different companies on the market which differ in the structure of the used meshes and anchors. A new objective measurement method to compare different properties of MiniSling systems (mesh and anchor) is presented in this article. Ballistic gelatine acts as soft tissue surrogate. Significant differences in parameters like pull-out strength of anchors or shrinkage of meshes under loading conditions have been determined. The form and size of the anchors as well as the structural stability of the meshes are decisive for a proper integration. The tested anchorings sytems showed markedly different mechanical function at their respective load bearing capacity. As the stable fixation of the device in tissue is a prerequisite for a permanet reinforcement, the proposed test system permits further optimisation of anchor and mesh devices to improve the success of the surgical treatment},
  language  = {en}
}
@article{LeimenaArtmannDachwaldetal.2010,
  author    = {Leimena, W. and Artmann, Gerhard and Dachwald, Bernd and Temiz Artmann, Ayseg{\"u}l and Gossmann, Matthias and Digel, Ilya},
  title     = {Feasibility of an in-situ microbial decontamination of an ice-melting probe},
  series = {Eurasian Chemico-Technological Journal. 12 (2010), H. 2},
  journal   = {Eurasian Chemico-Technological Journal. 12 (2010), H. 2},
  isbn      = {1562-3920},
  pages     = {145 -- 150},
  year      = {2010},
  language  = {en}
}
@article{AminTemizArtmannArtmannetal.2009,
  author    = {Amin, Rashid and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard and Lazarovici, Philip and Lelkes, Peter I.},
  title     = {Permeability of an In Vitro Model of Blood Brain Barrier (BBB)},
  series = {13th International Conference on Biomedical Engineering / Lim, Chwee Teck [Ed.]},
  journal   = {13th International Conference on Biomedical Engineering / Lim, Chwee Teck [Ed.]},
  isbn      = {978-3-540-92841-6},
  pages     = {81 -- 84},
  year      = {2009},
  language  = {en}
}
@article{BehbahaniMaiBergmannetal.2010,
  author    = {Behbahani, Mehdi and Mai, A. and Bergmann, B. and Waluga, C. and Behr, M. and Tran, L. and Vonderstein, K. and Mottaghy, K.},
  title     = {Modeling and Numerical Simulation of Blood Damage},
  year      = {2010},
  language  = {en}
}
@article{BehbahaniWalugaArltetal.2008,
  author    = {Behbahani, Mehdi and Waluga, C. and Arlt, S. and Behr, M. and Mottaghy, K.},
  title     = {Computational Analysis of Platelet Aggregation in a Taylor-Couette System},
  series = {The International Journal of Artificial Organs. 31 (2008), H. 7},
  journal   = {The International Journal of Artificial Organs. 31 (2008), H. 7},
  isbn      = {0391-3988},
  pages     = {643},
  year      = {2008},
  language  = {en}
}
@article{BehbahaniMaiWalugaetal.2010,
  author    = {Behbahani, Mehdi and Mai, A. and Waluga, C. and Bergmann, B. and Tran, L. and Vonderstein, K. and Behr, M. and Mottaghy, K.},
  title     = {Numerical Modeling of Flow-Related Thrombus Formation under Physiological and Non-Physiological Flow Conditions},
  series = {Acta Physiologica},
  volume    = {198},
  journal   = {Acta Physiologica},
  number    = {Supplement 677},
  isbn      = {1748-1716},
  pages     = {185},
  year      = {2010},
  language  = {en}
}
@article{BehbahaniProbstMaietal.2010,
  author    = {Behbahani, Mehdi and Probst, M. and Mai, A. and Behr, M. and Tran, L. and Vonderstein, K. and Mottaghy, K.},
  title     = {Numerical Prediction of Blood Damage in Biomedical Devices},
  year      = {2010},
  language  = {en}
}
@article{ProbstBehbahaniBorrmannetal.2010,
  author    = {Probst, M. and Behbahani, Mehdi and Borrmann, E. and Elgeti, S. and Nicolai, M. and Behr, M.},
  title     = {Hemodynamic Modeling for Numerical Analysis and Design of Medical Devices},
  year      = {2010},
  language  = {en}
}