@article{ScholzLeyDachwaldetal.2010, author = {Scholz, A. and Ley, Wilfried and Dachwald, Bernd and Miau, J. J. and Juang, J. C.}, title = {Flight results of the COMPASS-1 picosatellite mission}, series = {Acta Astronautica. 67 (2010), H. 9-10}, journal = {Acta Astronautica. 67 (2010), H. 9-10}, isbn = {0094-5765}, pages = {1289 -- 1298}, year = {2010}, language = {en} } @article{SchollSchubertZieneretal.2010, author = {Scholl, Ingrid and Schubert, N. and Ziener, P. and Pietrzyk, U.}, title = {GPU-basiertes Volumenrendering von multimodalen medizinischen Bilddaten in Echtzeit}, series = {Bildverarbeitung f{\"u}r die Medizin 2010 : Algorithmen, Systeme, Anwendungen ; Proceedings des Workshops vom 14. bis 16. M{\"a}rz in Aachen / Thomas M. Deserno ... (Hrsg.)}, journal = {Bildverarbeitung f{\"u}r die Medizin 2010 : Algorithmen, Systeme, Anwendungen ; Proceedings des Workshops vom 14. bis 16. M{\"a}rz in Aachen / Thomas M. Deserno ... (Hrsg.)}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-642-11967-5}, pages = {400 -- 404}, year = {2010}, language = {de} } @inproceedings{SchoeneReisgenSchleseretal.2010, author = {Schoene, Jens and Reisgen, Uwe and Schleser, Markus and Jerabek, Jakub and Chudoba, Rostislav}, title = {Theoretical and experimental investigations on textile-reinforced concrete spalling behavior}, series = {8th International PhD Symposium in Civil Engineering : Lyngby, June 20-23, 2010 : proceedings}, booktitle = {8th International PhD Symposium in Civil Engineering : Lyngby, June 20-23, 2010 : proceedings}, editor = {Fisher, Gregor}, publisher = {Technical University of Denmark, Dept. of Civil Engineering}, address = {Lyngby}, organization = {PhD Symposium in Civil Engineering <8, 2010, Lyngby> ; International Federation for Structural Concrete}, isbn = {9788778773012}, pages = {383 -- 388}, year = {2010}, language = {en} } @inproceedings{SchnellFranzenGligorevic2010, author = {Schnell, Michael and Franzen, Nico and Gligorevic, Snjezana}, title = {L-DACS1 laboratory demonstrator development and compatibility measurement set-up}, series = {IEEE/AIAA 29th Digital Avionics Systems Conference (DASC) : 3 - 7 Oct. 2010, Salt Lake City, Utah}, booktitle = {IEEE/AIAA 29th Digital Avionics Systems Conference (DASC) : 3 - 7 Oct. 2010, Salt Lake City, Utah}, organization = {Institute of Electrical and Electronics Engineers}, isbn = {9781424466160 ; 9781424466184}, pages = {3E3-1 -- 3E3-11}, year = {2010}, language = {en} } @article{SchneiderSchneider2010, author = {Schneider, Bettina and Schneider, Wilhelm}, title = {Die Konzernrechnungslegung}, series = {Das Wirtschaftsstudium : wisu ; Zeitschrift f{\"u}r Ausbildung, Examen, Berufseinstieg und Fortbildung. 39 (2010), H. 7}, journal = {Das Wirtschaftsstudium : wisu ; Zeitschrift f{\"u}r Ausbildung, Examen, Berufseinstieg und Fortbildung. 39 (2010), H. 7}, isbn = {0340-3084}, pages = {938 -- 942}, year = {2010}, language = {de} } @article{SchneiderSchneider2010, author = {Schneider, Bettina and Schneider, Wilhelm}, title = {Die Fallstudie: Konzernrechnungslegung}, series = {Das Wirtschaftsstudium : wisu ; Zeitschrift f{\"u}r Ausbildung, Examen, Berufseinstieg und Fortbildung}, volume = {39}, journal = {Das Wirtschaftsstudium : wisu ; Zeitschrift f{\"u}r Ausbildung, Examen, Berufseinstieg und Fortbildung}, number = {11}, isbn = {0340-3084}, pages = {1495 -- 1498}, year = {2010}, language = {de} } @article{SchmittSchollCaietal.2010, author = {Schmitt, Robert and Scholl, Ingrid and Cai, Yu and Xia, Ji and Dziwoki, Paul and Harding, Martin and Pavim, Alberto}, title = {Machine Vision System for Inline Inspection in Carbide Insert Production}, series = {Bildverarbeitung f{\"u}r die Medizin 2010 : Algorithmen, Systeme, Anwendungen ; Proceedings des Workshops vom 14. bis 16. M{\"a}rz in Aachen / Thomas M. Deserno ... (Hrsg.)}, journal = {Bildverarbeitung f{\"u}r die Medizin 2010 : Algorithmen, Systeme, Anwendungen ; Proceedings des Workshops vom 14. bis 16. M{\"a}rz in Aachen / Thomas M. Deserno ... (Hrsg.)}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-642-11967-5}, pages = {339 -- 342}, year = {2010}, language = {de} } @inproceedings{SchmiegelKochDittmeretal.2010, author = {Schmiegel, A. and Koch, K. and Dittmer, M. and Braun, M. and Landau, M. and Dick, C. and Bragard, Michael and [u.a.],}, title = {Das Sol-ion System : ein System zur Optimierung des Eigenverbrauchs von PV-Strom}, series = {Photovoltaische Solarenergie : 25. Symposium ; 03. - 05. M{\"a}rz 2010, Kloster Banz, Bad Staffelstein. - (Wissen f{\"u}r Profis)}, booktitle = {Photovoltaische Solarenergie : 25. Symposium ; 03. - 05. M{\"a}rz 2010, Kloster Banz, Bad Staffelstein. - (Wissen f{\"u}r Profis)}, publisher = {OTTI, Ostbayerisches Technologie-Transfer-Inst.}, address = {Regensburg}, isbn = {978-3-941785-23-6}, pages = {354 -- 359}, year = {2010}, language = {de} } @article{SchlamannYoonMaderwaldetal.2010, author = {Schlamann, Marc and Yoon, Min-Suk and Maderwald, Stefan and Pietrzyk, Thomas and Bitz, Andreas and Gerwig, Marcus and Forsting, Michael and Ladd, Susanne C. and Ladd, Mark E. and Kastrup, Oliver}, title = {Short term effects of magnetic resonance imaging on excitability of the motor cortex at 1.5T and 7T}, series = {Academic Radiology}, volume = {17}, journal = {Academic Radiology}, number = {3}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1076-6332}, doi = {10.1016/j.acra.2009.10.004}, pages = {277 -- 281}, year = {2010}, abstract = {Rationale and Objectives The increasing spread of high-field and ultra-high-field magnetic resonance imaging (MRI) scanners has encouraged new discussion of the safety aspects of MRI. Few studies have been published on possible cognitive effects of MRI examinations. The aim of this study was to examine whether changes are measurable after MRI examinations at 1.5 and 7 T by means of transcranial magnetic stimulation (TMS). Materials and Methods TMS was performed in 12 healthy, right-handed male volunteers. First the individual motor threshold was specified, and then the cortical silent period (SP) was measured. Subsequently, the volunteers were exposed to the 1.5-T MRI scanner for 63 minutes using standard sequences. The MRI examination was immediately followed by another TMS session. Fifteen minutes later, TMS was repeated. Four weeks later, the complete setting was repeated using a 7-T scanner. Control conditions included lying in the 1.5-T scanner for 63 minutes without scanning and lying in a separate room for 63 minutes. TMS was performed in the same way in each case. For statistical analysis, Wilcoxon's rank test was performed. Results Immediately after MRI exposure, the SP was highly significantly prolonged in all 12 subjects at 1.5 and 7 T. The motor threshold was significantly increased. Fifteen minutes after the examination, the measured value tended toward normal again. Control conditions revealed no significant differences. Conclusion MRI examinations lead to a transient and highly significant alteration in cortical excitability. This effect does not seem to depend on the strength of the static magnetic field.}, language = {en} } @article{SchlamannVoigtMaderwaldetal.2010, author = {Schlamann, Marc and Voigt, Melanie A. and Maderwald, Stefan and Bitz, Andreas and Kraff, Oliver and Ladd, Susanne C. and Ladd, Mark E. and Forsting, Michael and Wilhelm, Hans}, title = {Exposure to high-field MRI does not affect cognitive function}, series = {Journal of Magnetic Resonance Imaging}, volume = {31}, journal = {Journal of Magnetic Resonance Imaging}, number = {5}, publisher = {Wiley-Liss}, address = {New York}, issn = {1522-2586}, doi = {10.1002/jmri.22065}, pages = {1061 -- 1066}, year = {2010}, abstract = {Purpose To assess potential cognitive deficits under the influence of static magnetic fields at various field strengths some studies already exist. These studies were not focused on attention as the most vulnerable cognitive function. Additionally, mostly no magnetic resonance imaging (MRI) sequences were performed. Materials and Methods In all, 25 right-handed men were enrolled in this study. All subjects underwent one MRI examination of 63 minutes at 1.5 T and one at 7 T within an interval of 10 to 30 days. The order of the examinations was randomized. Subjects were referred to six standardized neuropsychological tests strictly focused on attention immediately before and after each MRI examination. Differences in neuropsychological variables between the timepoints before and after each MRI examination were assessed and P-values were calculated Results Only six subtests revealed significant differences between pre- and post-MRI. In these tests the subjects achieved better results in post-MRI testing than in pre-MRI testing (P = 0.013-0.032). The other tests revealed no significant results. Conclusion The improvement in post-MRI testing is only explicable as a result of learning effects. MRI examinations, even in ultrahigh-field scanners, do not seem to have any persisting influence on the attention networks of human cognition immediately after exposure.}, language = {en} } @article{SchifferFerreinLakemeyer2010, author = {Schiffer, Stefan and Ferrein, Alexander and Lakemeyer, Gerhard}, title = {Proceedings of the Fourth International Conference on Intelligent Robotics and Applications (ICIRA 2011)}, series = {Proceedings of the Fourth International Conference on Intelligent Robotics and Applications (ICIRA 2011)}, journal = {Proceedings of the Fourth International Conference on Intelligent Robotics and Applications (ICIRA 2011)}, pages = {1 -- 10}, year = {2010}, language = {en} } @article{Schermutzki2010, author = {Schermutzki, Margret}, title = {In Modulen lehren, lernen und pr{\"u}fen}, series = {In Modulen lehren, lernen und pr{\"u}fen. Herausforderungen an die Hochschuldidaktik / Terbuyken, Gregor [Hrsg.]}, journal = {In Modulen lehren, lernen und pr{\"u}fen. Herausforderungen an die Hochschuldidaktik / Terbuyken, Gregor [Hrsg.]}, address = {Rehburg-Loccum}, isbn = {978-3-8172-7809-1}, pages = {81 -- 106}, year = {2010}, language = {de} } @book{Schelthoff2010, author = {Schelthoff, Christof}, title = {Mathematik im ingenieurwissenschaftlichen Bachelorstudium / 4., {\"u}berarb. Aufl.}, publisher = {Shaker}, address = {Aachen}, isbn = {978-3-8322-9288-1}, pages = {542 S. : graph. Darst.}, year = {2010}, language = {de} } @book{Schelthoff2010, author = {Schelthoff, Christof}, title = {Mathematik im ingenieurwissenschaftlichen Bachelorstudium : L{\"o}sung der {\"U}bungs- und Klausuraufgaben}, publisher = {Shaker}, address = {Aachen}, isbn = {978-3-8322-9502-8}, pages = {171 S. : Ill., graph. Darst.}, year = {2010}, language = {de} } @article{ScheerRossKapelyukhetal.2010, author = {Scheer, Nico and Ross, Jillian and Kapelyukh, Yury and Rode, Anja and Wolf, C. Roland}, title = {In vivo responses of the human and murine pregnane X receptor to dexamethasone in mice}, series = {Drug Metabolism and Disposition}, volume = {38}, journal = {Drug Metabolism and Disposition}, number = {7}, publisher = {ASPET}, address = {Bethesda}, issn = {1521-009X}, doi = {10.1124/dmd.109.031872}, pages = {1046 -- 1053}, year = {2010}, abstract = {Dexamethasone (DEX) is a potent and widely used anti-inflammatory and immunosuppressant glucocorticoid. It can bind and activate the pregnane X receptor (PXR), which plays a critical role as xenobiotic sensor in mammals to induce the expression of many enzymes, including cytochromes P450 in the CYP3A family. This induction results in its own metabolism. We have used a series of transgenic mouse lines, including a novel, improved humanized PXR line, to compare the induction profile of PXR-regulated drug-metabolizing enzymes after DEX administration, as well as looking at hepatic responses to rifampicin (RIF). The new humanized PXR model has uncovered further intriguing differences between the human and mouse receptors in that RIF only induced Cyp2b10 in the new humanized model. DEX was found to be a much more potent inducer of Cyp3a proteins in wild-type mice than in mice humanized for PXR. To assess whether PXR is involved in the detoxification of DEX in the liver, we analyzed the consequences of high doses of the glucocorticoid on hepatotoxicity on different PXR genetic backgrounds. We also studied these effects in an additional mouse model in which functional mouse Cyp3a genes have been deleted. These strains exhibited different sensitivities to DEX, indicating a protective role of the PXR and CYP3A proteins against the hepatotoxicity of this compound.}, language = {en} } @article{RossPlummerRodeetal.2010, author = {Ross, Jillian and Plummer, Simon M. and Rode, Anja and Scheer, Nico and Bower, Conrad C. and Vogel, Ortwin and Henderson, Colin J. and Wolf, C. Roland and Elcombe, Clifford R.}, title = {Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo}, series = {Toxicological Sciences}, volume = {116}, journal = {Toxicological Sciences}, number = {2}, publisher = {Oxford University Press}, address = {Oxford}, issn = {1096-0929}, doi = {10.1093/toxsci/kfq118}, pages = {452 -- 466}, year = {2010}, abstract = {Mouse nongenotoxic hepatocarcinogens phenobarbital (PB) and chlordane induce hepatomegaly characterized by hypertrophy and hyperplasia. Increased cell proliferation is implicated in the mechanism of tumor induction. The relevance of these tumors to human health is unclear. The xenoreceptors, constitutive androstane receptors (CARs), and pregnane X receptor (PXR) play key roles in these processes. Novel "humanized" and knockout models for both receptors were developed to investigate potential species differences in hepatomegaly. The effects of PB (80 mg/kg/4 days) and chlordane (10 mg/kg/4 days) were investigated in double humanized PXR and CAR (huPXR/huCAR), double knockout PXR and CAR (PXRKO/CARKO), and wild-type (WT) C57BL/6J mice. In WT mice, both compounds caused increased liver weight, hepatocellular hypertrophy, and cell proliferation. Both compounds caused alterations to a number of cell cycle genes consistent with induction of cell proliferation in WT mice. However, these gene expression changes did not occur in PXRKO/CARKO or huPXR/huCAR mice. Liver hypertrophy without hyperplasia was demonstrated in the huPXR/huCAR animals in response to both compounds. Induction of the CAR and PXR target genes, Cyp2b10 and Cyp3a11, was observed in both WT and huPXR/huCAR mouse lines following treatment with PB or chlordane. In the PXRKO/CARKO mice, neither liver growth nor induction of Cyp2b10 and Cyp3a11 was seen following PB or chlordane treatment, indicating that these effects are CAR/PXR dependent. These data suggest that the human receptors are able to support the chemically induced hypertrophic responses but not the hyperplastic (cell proliferation) responses. At this time, we cannot be certain that hCAR and hPXR when expressed in the mouse can function exactly as the genes do when they are expressed in human cells. However, all parameters investigated to date suggest that much of their functionality is maintained.}, language = {en} } @inproceedings{RitzStrauch2010, author = {Ritz, Thomas and Strauch, Jakob}, title = {„Offline Strategie"-Patterns f{\"u}r mobile SOA Prozesse}, series = {Mobile und ubiquit{\"a}re Informationssysteme : Technologien, Anwendungen und Dienste zur Unterst{\"u}tzung von mobiler Kollaboration ; Proceedings zur 5. Konferenz Mobile und Ubiquit{\"a}re Informationssysteme (MMS 2010) ; 23. - 25. Februar 2010 in G{\"o}ttingen, Germany. - (GI-Edition : Proceedings ; 163)}, booktitle = {Mobile und ubiquit{\"a}re Informationssysteme : Technologien, Anwendungen und Dienste zur Unterst{\"u}tzung von mobiler Kollaboration ; Proceedings zur 5. Konferenz Mobile und Ubiquit{\"a}re Informationssysteme (MMS 2010) ; 23. - 25. Februar 2010 in G{\"o}ttingen, Germany. - (GI-Edition : Proceedings ; 163)}, editor = {Bick, Markus}, publisher = {Gesellschaft f{\"u}r Informatik}, address = {Bonn}, isbn = {978-3-88579-257-4}, pages = {174 -- 180}, year = {2010}, language = {de} } @inproceedings{RisseBolleMueller2010, author = {Risse, Henry and Bolle, Friedrich-Wilhelm and M{\"u}ller, Karsten}, title = {Energiebilanzen und -potenziale von Abwasseranlagen : Vorstellung neuer Untersuchungsvorhaben in NRW}, series = {11. K{\"o}lner Kanal- und Kl{\"a}ranlagen-Kolloquium am 29. und 30. Sept. 2010. Aachener Schriften zur Stadtentw{\"a}sserung ASS. Bd. 14}, booktitle = {11. K{\"o}lner Kanal- und Kl{\"a}ranlagen-Kolloquium am 29. und 30. Sept. 2010. Aachener Schriften zur Stadtentw{\"a}sserung ASS. Bd. 14}, publisher = {Ges. zur F{\"o}rderung der Siedlungswasserwirtschaft an der RWTH Aachen}, address = {Aachen}, isbn = {978-3-938996-07-2}, pages = {27/1 -- 27/16}, year = {2010}, language = {de} } @article{RiglingEilmannKoechlietal.2010, author = {Rigling, Andreas and Eilmann, Britta and Koechli, Roger and Dobbertin, Matthias}, title = {Mistletoe-induced crown degradation in Scots pine in a xeric environment}, volume = {30}, number = {7}, publisher = {Oxford University Press}, address = {Oxford}, issn = {1758-4469 (Online)}, doi = {10.1093/treephys/tpq038}, pages = {845 -- 832}, year = {2010}, abstract = {Increasing Scots pine (Pinus sylvestris L.) mortality has been recently observed in the dry inner valleys of the European Alps. Besides drought, infection with pine mistletoe (Viscum album ssp. austriacum) seems to play an important role in the mortality dynamics of Scots pines, but how mistletoes promote pine decline remains unclear. To verify whether pine mistletoe infection weakens the host via crown degradation, as observed for dwarf mistletoes, we studied the negative effects of pine mistletoe infestation on the photosynthetic tissues and branch growth of pairs of infested and non-infested branches. Pine mistletoe infection leads to crown degradation in its host by reducing the length, the radial increment, the ramification, the needle length and the number of needle years of the infested branches. This massive loss in photosynthetic tissue results in a reduction in primary production and a subsequent decrease in carbohydrate availability. The significant reduction in needle length due to mistletoe infection is an indication for a lower water and nutrient availability in infested branches. Thus, mistletoe infection might lead to a decrease in the availability of water and carbohydrates, the two most important growth factors, which are already shortened due to the chronic drought situation in the area. Therefore, pine mistletoe increases the risk of drought-induced mortality of its host when growing in a xeric environment.}, language = {en} } @article{RibitschKarlBirnerGruenbergeretal.2010, author = {Ribitsch, D. and Karl, W. and Birner-Gruenberger, R. and Gruber, K. and Eiteljoerg, I. and Remler, P. and Wieland, S. and Siegert, Petra and Maurer, Karl-Heinz and Schwab, H.}, title = {C-terminal truncation of a metagenome-derived detergent protease for effective expression in E. coli}, series = {Journal of biotechnology}, volume = {150}, journal = {Journal of biotechnology}, number = {3}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-4863 (E-Journal); 0168-1656 (Print)}, doi = {10.1016/j.jbiotec.2010.09.947}, pages = {408 -- 416}, year = {2010}, abstract = {Recently, a new alkaline protease named HP70 showing highest homology to extracellular serine proteases of Stenotrophomonas maltophilia and Xanthomonas campestris was found in the course of a metagenome screening for detergent proteases (Niehaus et al., submitted for publication). Attempts to efficiently express the enzyme in common expression hosts had failed. This study reports on the realization of overexpression in Escherichia coli after structural modification of HP70. Modelling of HP70 resulted in a two-domain structure, comprising the catalytic domain and a C-terminal domain which includes about 100 amino acids. On the basis of the modelled structure the enzyme was truncated by deletion of most of the C-terminal domain yielding HP70-C477. This structural modification allowed effective expression of active enzyme using E. coli BL21-Gold as the host. Specific activity of HP70-C477 determined with suc-l-Ala-l-Ala-l-Pro-l-Phe-p-nitroanilide as the substrate was 30 ± 5 U/mg compared to 8 ± 1 U/mg of the native enzyme. HP70-C477 was most active at 40 °C and pH 7-11; these conditions are prerequisite for a potential application as detergent enzyme. Determination of kinetic parameters at 40 °C and pH = 9.5 resulted in KM = 0.23 ± 0.01 mM and kcat = 167.5 ± 3.6 s⁻¹. MS-analysis of peptide fragments obtained from incubation of HP70 and HP70-C477 with insulin B indicated that the C-terminal domain influences the cleavage preferences of the enzyme. Washing experiments confirmed the high potential of HP70-C477 as detergent protease.}, language = {en} }