@article{FeichtingerEilmannBuchmannetal.2014, author = {Feichtinger, Linda M. and Eilmann, Britta and Buchmann, Nina and Rigling, Andreas}, title = {Growth adjustments of conifers to drought and to century-long irrigation}, series = {Forest Ecology and Management}, volume = {2014}, journal = {Forest Ecology and Management}, number = {334}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1872-7042 (Online)}, doi = {10.1016/j.foreco.2014.08.008}, pages = {96 -- 105}, year = {2014}, abstract = {Our knowledge on tree responses to drought is mainly based on short-term manipulation experiments which do not capture any possible long-term adjustments in this response. Therefore, historical water channels in inner-Alpine dry valleys were used as century-long irrigation experiments to investigate adjustments in tree growth to contrasting water supply. This involved quantifying the tree-ring growth of irrigated and non-irrigated (control) Scots pine (Pinus sylvestris L.) in Valais (Switzerland), as well as European larch (Larix decidua Mill.) and black pine (Pinus nigra Arnold) in Vinschgau (Italy). Furthermore, the adjustments in radial growth of Scots pine and European larch to an abrupt stop in irrigation were analyzed. Irrigation promoted the radial growth of all tree species investigated compared to the control: (1) directly through increased soil water availability, and (2) indirectly through increased soil nutrients and humus contents in the irrigated plots. Irrigation led to a full elimination of growth responses to climate for European larch and black pine, but not for Scots pine, which might become more sensitive to drought with increasing tree size in Valais. For the control trees, the response of the latewood increment to water availability in July/August has decreased in recent decades for all species, but increased in May for Scots pine only. The sudden irrigation stop caused a drop in radial growth to a lower level for Scots pine or similar level for larch compared to the control for up to ten years. However, both tree species were then able to adjust to the new conditions and subsequently grew with similar (Scots pine) or even higher growth rates (larch) than the control. To estimate the impact of climate change on future forest development, the duration of manipulation experiments should be on longer time scales in order to capture adjustment processes and feedback mechanisms of forest ecosystems.}, language = {en} } @article{Laack2014, author = {Laack, Walter van}, title = {Nahtoderfahrungen aus medizinischer Sicht}, series = {Deutsche medizinische Wochenschrift : DMW}, volume = {Jg. 139}, journal = {Deutsche medizinische Wochenschrift : DMW}, number = {H. 51/52}, publisher = {Thieme}, address = {Stuttgart}, issn = {1439-4413 (E-Journal); 0012-0472 (Print); 1437-5982 (Print)}, doi = {10.1055/s-0034-1387363}, pages = {2651 -- 2654}, year = {2014}, abstract = {Nah- versus Nachtoderfahrungen Nahtoderfahrungen (NTE) sind ein Ph{\"a}nomen aus der Kategorie „außergew{\"o}hnliche Bewusstseinserfahrungen". Sie treten in unmittelbarer N{\"a}he des eigenen Todes auf. Oft, aber nicht immer, handelt es sich dabei um Erfahrungen von Personen, die durch {\"a}rztliche Maßnahmen wiederbelebt wurden und sp{\"a}ter davon berichten (NTE-ler). Jedoch kommen solche Ph{\"a}nomene auch bei Menschen vor, die w{\"a}hrend einer schweren Erkrankung eine lebensbedrohliche Krise haben, hiervon aber spontan genesen. Den NTE {\"a}hnlich sind auch sogenannte Nachtod-erfahrungen sowie spontane Erlebnisse, die im Rahmen anderer außergew{\"o}hnlicher Stresssituationen auftreten. Von Nachtoderfahrungen spricht man, wenn die Betroffenen anl{\"a}sslich des Todes von geliebten Angeh{\"o}rigen oder Freunden Erlebnisse haben, die inhaltlich ebenfalls, zumindest aber teilweise, denen von NTE entsprechen. Nachtoderfahrungen sowie spontane NTE-{\"a}hnliche Erlebnisse unterscheiden sich jedoch von den echten NTE zumeist sowohl quantitativ als auch qualitativ. Unter einem quantitativen Unterschied versteht man in diesem Zusammenhang eine in der Regel geringer ausgepr{\"a}gte Komplexit{\"a}t, als sie sehr vielen NTE zu eigen ist. Da sich aber auch viele NTE selbst bez{\"u}glich ihrer Komplexit{\"a}t unterscheiden, ist der Hauptunterschied qualitativer Natur: Echte NTE besitzen gegen{\"u}ber den anderen hier erw{\"a}hnten Ph{\"a}nomenen eine gr{\"o}ßere inhaltliche und emotionale Tiefe. Sie begleiten die Betroffenen anschließend ein Leben lang - zumeist mit positiven, in Einzelf{\"a}llen aber auch mit negativen Folgen, die bis zu einem sp{\"a}teren Suizid reichen k{\"o}nnen. Die genannten außergew{\"o}hnlichen Bewusstseinsph{\"a}nomene lassen sich in ihrer Gesamtheit bei rund 5 \% der Bev{\"o}lkerung finden. NTE im Speziellen haben hiervon einen durchaus bedeutenden Anteil. Je nach Studie geben zwischen 18 \% und 40 \% aller Personen, die reanimiert wurden, an, w{\"a}hrenddessen eine NTE erlebt zu haben. Dass nicht alle eine solche Erfahrung machen, wird von Kritikern gern dahingehend interpretiert, NTE seien rein physiologischer und keineswegs spiritueller Natur. Jedoch sollte man bedenken, dass im Fall einer rein neurophysiologischen Grundlage von NTE dann bei jedem ein solches Ph{\"a}nomen zu erwarten w{\"a}re, so wie beispielsweise auch die Symptome einer Hypoglyk{\"a}mie im Wesentlichen immer dieselben sind.}, language = {de} } @article{LeandroBungCarvalho2014, author = {Leandro, J. and Bung, Daniel Bernhard and Carvalho, R.}, title = {Measuring void fraction and velocity fields of a stepped spillway for skimming flow using non-intrusive methods}, series = {Experiments in fluids}, journal = {Experiments in fluids}, number = {55}, publisher = {Springer Nature}, address = {Heidelberg}, issn = {0723-4864 (Print) ; 1432-1114 (Online)}, doi = {10.1007/s00348-014-1732-6}, pages = {Art. 1732}, year = {2014}, language = {en} } @article{RatkeMilowLisinskietal.2014, author = {Ratke, Lorenz and Milow, Barbara and Lisinski, Susanne and Hoepfner, Sandra}, title = {On an effect of fine ceramic particles on the structure of aerogels}, series = {Microgravity science and technology}, volume = {26}, journal = {Microgravity science and technology}, publisher = {Springer Nature}, address = {Heidelberg}, issn = {0938-0108 ; 1875-0494}, doi = {10.1007/s12217-014-9380-2}, pages = {103 -- 110}, year = {2014}, language = {en} } @article{AlmajhdiSengerAmeretal.2014, author = {Almajhdi, Fahad N. and Senger, Tilo and Amer, Haitham M. and Gissmann, Lutz and {\"O}hlschl{\"a}ger, Peter}, title = {Design of a highly effective therapeutic HPV16 E6/E7-specific DNA vaccine: optimization by different ways of sequence rearrangements (Shuffling)}, series = {PLOS one}, volume = {11}, journal = {PLOS one}, number = {9}, publisher = {PLOS}, address = {San Francisco}, issn = {1932-6203}, doi = {10.1371/journal.pone.0113461}, pages = {e113461}, year = {2014}, abstract = {Persistent infection with the high-risk Human Papillomavirus type 16 (HPV 16) is the causative event for the development of cervical cancer and other malignant tumors of the anogenital tract and of the head and neck. Despite many attempts to develop therapeutic vaccines no candidate has entered late clinical trials. An interesting approach is a DNA based vaccine encompassing the nucleotide sequence of the E6 and E7 viral oncoproteins. Because both proteins are consistently expressed in HPV infected cells they represent excellent targets for immune therapy. Here we report the development of 8 DNA vaccine candidates consisting of differently rearranged HPV-16 E6 and E7 sequences within one molecule providing all naturally occurring epitopes but supposedly lacking transforming activity. The HPV sequences were fused to the J-domain and the SV40 enhancer in order to increase immune responses. We demonstrate that one out of the 8 vaccine candidates induces very strong cellular E6- and E7- specific cellular immune responses in mice and, as shown in regression experiments, efficiently controls growth of HPV 16 positive syngeneic tumors. This data demonstrates the potential of this vaccine candidate to control persistent HPV 16 infection that may lead to malignant disease. It also suggests that different sequence rearrangements influence the immunogenecity by an as yet unknown mechanism.}, language = {en} } @article{BaeckerSchusserPoghossianetal.2014, author = {B{\"a}cker, Matthias and Schusser, Sebastian and Poghossian, Arshak and Sch{\"o}ning, Michael Josef}, title = {Multi-Parametererfassung mit siliziumbasiertem Sensorchip: Aus Drei mach Eins}, series = {GIT Labor-Fachzeitschrift}, journal = {GIT Labor-Fachzeitschrift}, number = {2}, publisher = {Wiley}, issn = {0016-3538}, pages = {28 -- 30}, year = {2014}, language = {de} } @article{Timme2014, author = {Timme, Michael}, title = {BGH: Geltendmachung von Sachm{\"a}ngeln bei Wohnungseigentum}, series = {LMK : Fachdienst Zivilrecht : Kommentierte BGH-Rechtsprechung}, volume = {2014}, journal = {LMK : Fachdienst Zivilrecht : Kommentierte BGH-Rechtsprechung}, number = {5}, publisher = {Beck}, address = {M{\"u}nchen}, issn = {1611-1095}, year = {2014}, language = {de} } @article{KluczkaEcksteinAlexopoulosetal.2014, author = {Kluczka, Sven and Eckstein, Julian and Alexopoulos, Spiros and Vaeßen, Christiane and Roeb, Martin}, title = {Process simulation for solar steam and dry reforming}, series = {Energy procedia : Proceedings of the SolarPACES 2013 International Conference}, volume = {49}, journal = {Energy procedia : Proceedings of the SolarPACES 2013 International Conference}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1876-6102 (E-Journal)}, doi = {10.1016/j.egypro.2014.03.092}, pages = {850 -- 859}, year = {2014}, abstract = {In co-operation with the German Aerospace Center, the Solar-Institut J{\"u}lich has been analyzing the different technologies that are available for methanol production from CO2 using solar energy. The aim of the project is to extract CO2 from industrial exhaust gases or directly from the atmosphere to recycle it by use of solar energy. Part of the study was the modeling and simulating of a methane reformer for the production of synthesis gas, which can be operated by solar or hybrid heat sources. The reformer has been simplified in such a way that the model is accurate and enables fast calculations. The developed pseudo-homogeneous one- dimensional model can be regarded as a kind of counter-current heat exchanger and is able to incorporate a steam reforming reaction as well as a dry reforming reaction.}, language = {en} } @article{MuellerHirschfeldLambertzetal.2014, author = {M{\"u}ller, Martin and Hirschfeld, Julian and Lambertz, Rita and Schulze Lohoff, Andreas and Lustfeld, Hans and Pfeifer, Heinz and Reißel, Martin}, title = {Validation of a novel method for detecting and stabilizing malfunctioning areas in fuel cell stacks}, series = {Journal of power sources}, volume = {272}, journal = {Journal of power sources}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-2755 (E-Journal); 0378-7753 (Print)}, doi = {10.1016/j.jpowsour.2014.08.045}, pages = {225 -- 232}, year = {2014}, abstract = {In this paper a setup for detecting malfunctioning areas of MEAs in fuel cell stacks is described. Malfunctioning areas generate electric cross currents inside bipolar plates. To exploit this we suggest bipolar plates consisting not of two but of three layers. The third one is a highly conducting layer and segmented such that the cross currents move along the segments to the surface of the stack where they can be measured by an inductive sensor. With this information a realistic model can be used to detect the malfunctioning area. Furthermore the third layer will prevent any current inhomogeneity of a malfunctioning cell to spread to neighbouring cells in the stack. In this work the results of measurements in a realistic cell setup will be compared with the results obtained in simulation studies with the same configuration. The basis for the comparison is the reliable characterisation of the electrical properties of the cell components and the implication of these results into the simulation model. The experimental studies will also show the limits in the maximum number of segments, which can be used for a reliable detection of cross currents.}, language = {en} } @article{HandtkeVollandMethlingetal.2014, author = {Handtke, Stefan and Volland, Sonja and Methling, Karen and Albrecht, Dirk and Becher, D{\"o}rte and Nehls, Jenny and Bongaerts, Johannes and Maurer, Karl-Heinz and Lalk, Michael and Liesegang, Heiko and Voigt, Birgit and Daniel, Rolf and Hecker, Michael}, title = {Cell physiology of the biotechnological relevant bacterium Bacillus pumilus - An omics-based approach}, series = {Journal of Biotechnology}, journal = {Journal of Biotechnology}, number = {192(A)}, publisher = {Elsevier}, address = {Amsterdam}, issn = {1873-4863 (E-Journal); 0168-1656 (Print)}, doi = {10.1016/j.jbiotec.2014.08.028}, pages = {204 -- 214}, year = {2014}, abstract = {Members of the species Bacillus pumilus get more and more in focus of the biotechnological industry as potential new production strains. Based on exoproteome analysis, B. pumilus strain Jo2, possessing a high secretion capability, was chosen for an omics-based investigation. The proteome and metabolome of B. pumilus cells growing either in minimal or complex medium was analyzed. In total, 1542 proteins were identified in growing B. pumilus cells, among them 1182 cytosolic proteins, 297 membrane and lipoproteins and 63 secreted proteins. This accounts for about 43\% of the 3616 proteins encoded in the B. pumilus Jo2 genome sequence. By using GC-MS, IP-LC/MS and H NMR methods numerous metabolites were analyzed and assigned to reconstructed metabolic pathways. In the genome sequence a functional secretion system including the components of the Sec- and Tat-secretion machinery was found. Analysis of the exoproteome revealed secretion of about 70 proteins with predicted secretion signals. In addition, selected production-relevant genome features such as restriction modification systems and NRPS clusters of B. pumilus Jo2 are discussed.}, language = {en} }