@article{MuellerVeggianBeuscherHaenni1980,
  author    = {M{\"u}ller-Veggian, Mattea and Beuscher, H. and Haenni, D. R.},
  title     = {Investigation of high-spin states in ¹³⁹ Nd},
  series = {Annual report 1979 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 72)},
  journal   = {Annual report 1979 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 72)},
  publisher = {Kernforschungsanlage},
  address   = {J{\"u}lich},
  pages     = {46},
  year      = {1980},
  language  = {en}
}
@article{IsmailHaradaYoshinobuetal.2000,
  author    = {Ismail, A.B.M. and Harada, T. and Yoshinobu, T. and Iwasaki, H. and Sch{\"o}ning, Michael Josef and L{\"u}th, H.},
  title     = {Investigation of pulsed laser-deposited Al2O3 as a high pH-sensitive layer for LAPS-based biosensing applications},
  series = {Sensors and Actuators B. 71 (2000), H. 3},
  journal   = {Sensors and Actuators B. 71 (2000), H. 3},
  isbn      = {0925-4005},
  pages     = {169 -- 172},
  year      = {2000},
  language  = {en}
}
@article{JansenBehbahaniLaumenetal.2010,
  author    = {Jansen, S. V. and Behbahani, Mehdi and Laumen, M. and Kaufmann, T. and Hormes, M. and Behr, M. and Schmitz-Rode, T. and Steinseifer, U.},
  title     = {Investigation of Steady Flow Through a Realistic Model of the Thoracic Human Aorta Using 3D Stereo PIV and CFD-Simulation},
  year      = {2010},
  language  = {en}
}
@article{MuellerVeggianHamacherKinast1994,
  author    = {M{\"u}ller-Veggian, Mattea and Hamacher, A. and Kinast, R.},
  title     = {Investigation of the grooves on p-contacts of position-sensitive germanium detectors},
  series = {Annual report 1993 / Forschungszentrum J{\"u}lich Institut f{\"u}r Kernphysik / Baur, G. (Hrsg.). - (Berichte des Forschungszentrums J{\"u}lich ; 2879)},
  journal   = {Annual report 1993 / Forschungszentrum J{\"u}lich Institut f{\"u}r Kernphysik / Baur, G. (Hrsg.). - (Berichte des Forschungszentrums J{\"u}lich ; 2879)},
  publisher = {Forschungszentrum, Zentralbibliothek},
  address   = {J{\"u}lich},
  pages     = {308 S.},
  year      = {1994},
  language  = {en}
}
@article{MuellerVeggian1980,
  author    = {M{\"u}ller-Veggian, Mattea},
  title     = {Investigation of the preequilibrium reaction mechanism through the study of the isomer ratios ²¹¹,²¹² Po},
  series = {Annual report 1979 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 72)},
  journal   = {Annual report 1979 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 72)},
  publisher = {Verlag des Forschungszentrums J{\"u}lich},
  address   = {J{\"u}lich},
  pages     = {32},
  year      = {1980},
  language  = {en}
}
@article{BreuerMangSchoeningetal.2017,
  author    = {Breuer, Lars and Mang, Thomas and Sch{\"o}ning, Michael Josef and Thoelen, Ronald and Wagner, Torsten},
  title     = {Investigation of the spatial resolution of a laser-based stimulation process for light-addressable hydrogels with incorporated graphene oxide by means of IR thermography},
  series = {Sensors and Actuators A: Physical},
  volume    = {268},
  journal   = {Sensors and Actuators A: Physical},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0924-4247},
  doi       = {10.1016/j.sna.2017.11.031},
  pages     = {126 -- 132},
  year      = {2017},
  language  = {en}
}
@article{MuellerVeggianNeskakisLieder1976,
  author    = {M{\"u}ller-Veggian, Mattea and Neskakis, A. and Lieder, R. M.},
  title     = {Investigation of ¹⁸¹⁻¹⁸⁴ OS and ¹⁸¹ Re; evidence for p-backbending},
  series = {Annual report 1975 / Institut f{\"u}r Kernphysik Kernforschungsanlage J{\"u}lich / Ed. board: A. F{\"a}ßler ...},
  journal   = {Annual report 1975 / Institut f{\"u}r Kernphysik Kernforschungsanlage J{\"u}lich / Ed. board: A. F{\"a}ßler ...},
  publisher = {Verlag des Forschungszentrums J{\"u}lich},
  address   = {J{\"u}lich},
  pages     = {47},
  year      = {1976},
  language  = {en}
}
@article{ArtmannTrzewikSchmidSchoenbein2000,
  author    = {Artmann, Gerhard and Trzewik, J. and Schmid-Sch{\"o}nbein, G. W.},
  title     = {Investigation on lymphatic endothelial microvalves / Trzewik, J. ; Artmann, G. M. ; Schmid-Sch{\"o}nbein, G. W.},
  series = {Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1},
  journal   = {Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1},
  isbn      = {1862-278X},
  pages     = {521 -- 522},
  year      = {2000},
  language  = {en}
}
@article{AkimbekovDigelZhubanova2013,
  author    = {Akimbekov, N. Sh. and Digel, Ilya and Zhubanova, A. A.},
  title     = {Investigation the Influence of Carbonized Material Based On Rice Husk on Viability and Migration of Fibroblasts in T3B3 Cell Culture},
  series = {KazNU Bulletin. Biology series},
  volume    = {59},
  journal   = {KazNU Bulletin. Biology series},
  number    = {3/1},
  issn      = {1563-0218},
  pages     = {20 -- 23},
  year      = {2013},
  language  = {en}
}
@article{MuellerVeggianBeuscherHaenni1979,
  author    = {M{\"u}ller-Veggian, Mattea and Beuscher, H. and Haenni, D. R.},
  title     = {Investigations of high spin states in ¹³⁸,¹³⁹ Nd},
  series = {Annual report 1978 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 36)},
  journal   = {Annual report 1978 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 36)},
  publisher = {Kernforschungsanlage},
  address   = {J{\"u}lich},
  pages     = {24},
  year      = {1979},
  language  = {en}
}
@article{AkimbekovDigelSavitkayaetal.2013,
  author    = {Akimbekov, N.Sh. and Digel, Ilya and Savitkaya, I.S. and Zhubanova, A.A. and Tastambek, K.T.},
  title     = {Investigations of LPS endotoxin elimination in the flowing column conditions with the sorbent on the basis of carbonized rice husk},
  series = {KazNU Bulletin. Biology series},
  volume    = {57},
  journal   = {KazNU Bulletin. Biology series},
  number    = {1},
  issn      = {1563-0218},
  pages     = {124 -- 127},
  year      = {2013},
  language  = {en}
}
@article{SchoeningCrottRonkeletal.1996,
  author    = {Sch{\"o}ning, Michael Josef and Crott, M. and Ronkel, F. and Thust, M. and Schultze, J. W. and Kordos, P. and L{\"u}th, H.},
  title     = {Investigations on porous silicon layers with regard to chemical microsensor applications},
  series = {Third International Conference on Intelligent Materials : Lyon, 3-4-5 June 1996, Center of Congress "L'Espace T{\^e}te d'Or" / [publ. by SPIE, the International Society for Optical Engineering]. General chair/ed. by: P. F. Gobin},
  journal   = {Third International Conference on Intelligent Materials : Lyon, 3-4-5 June 1996, Center of Congress "L'Espace T{\^e}te d'Or" / [publ. by SPIE, the International Society for Optical Engineering]. General chair/ed. by: P. F. Gobin},
  publisher = {SPIE},
  address   = {Bellingham, Wash.},
  isbn      = {0819421650},
  pages     = {275 -- 280},
  year      = {1996},
  language  = {en}
}
@article{SchoeningBrunsHoffmannetal.1993,
  author    = {Sch{\"o}ning, Michael Josef and Bruns, M. and Hoffmann, W. and Hoffmann, B. (u.a.)},
  title     = {Iodide ion-sensitive field-effect structures},
  series = {Sensors and Actuators B. 15 (1993), H. 1-3},
  journal   = {Sensors and Actuators B. 15 (1993), H. 1-3},
  isbn      = {0925-4005},
  pages     = {192 -- 194},
  year      = {1993},
  language  = {en}
}
@article{WeckesserGriessmeierSchmidtetal.1998,
  author    = {Weckesser, Martin and Grießmeier, Martin and Schmidt, Daniela and Sonnenberg, Frank and Ziemons, Karl and Kemna, Lars and Holschbach, Marcus and Langen, Karl-J. and M{\"u}ller-G{\"a}rtner, Hans-W.},
  title     = {Iodine-123 α-methyl tyrosine single-photon emission tomography of cerebral gliomas: standardised evaluation of tumour uptake and extent},
  series = {European Journal of Nuclear Medicine},
  volume    = {25},
  journal   = {European Journal of Nuclear Medicine},
  number    = {2},
  isbn      = {1619-7089},
  pages     = {150 -- 156},
  year      = {1998},
  abstract  = {Single-photon emission tomography (SPET) with the amino acid analogue l-3-[123I]iodo-α-methyl tyrosine (IMT) is helpful in the diagnosis and monitoring of cerebral gliomas. Radiolabelled amino acids seem to reflect tumour infiltration more specifically than conventional methods like magnetic resonance imaging and computed tomography. Automatic tumour delineation based on maximal tumour uptake may cause an overestimation of mean tumour uptake and an underestimation of tumour extension in tumours with circumscribed peaks. The aim of this study was to develop a program for tumour delineation and calculation of mean tumour uptake which takes into account the mean background activity and is thus optimised to the problem of tumour definition in IMT SPET. Using the frequency distribution of pixel intensities of the tomograms a program was developed which automatically detects a reference brain region and draws an isocontour region around the tumour taking into account mean brain radioactivity. Tumour area and tumour/brain ratios were calculated. A three-compartment phantom was simulated to test the program. The program was applied to IMT SPET studies of 20 patients with cerebral gliomas and was compared to the results of manual analysis by three different investigators. Activity ratios and chamber extension of the phantom were correctly calculated by the automatic analysis. A method based on image maxima alone failed to determine chamber extension correctly. Manual region of interest analysis in patient studies resulted in a mean inter-observer standard deviation of 8.7\%±6.1\% (range 2.7\%-25.0\%). The mean value of the results of the manual analysis showed a significant correlation to the results of the automatic analysis (r = 0.91, P<0.0001 for the uptake ratio; r = 0.87, P<0.0001 for the tumour area). We conclude that the algorithm proposed simplifies the calculation of uptake ratios and may be used for observer-independent evaluation of IMT SPET studies. Three-dimensional tumour recognition and transfer to co-registered morphological images based on this program may be useful for the planning of surgical and radiation treatment.},
  language  = {en}
}
@article{MourzinaYoshinobuSchubertetal.2001,
  author    = {Mourzina, Y. G. and Yoshinobu, T. and Schubert, J. and L{\"u}th, H. and Iwasaki, H. and Sch{\"o}ning, Michael Josef},
  title     = {Ion-selective lightaddressable potentiometric sensor (LAPS) with chalcogenide thin film by pulsed laser deposition},
  series = {Sensors and Actuators B. 80 (2001), H. 2},
  journal   = {Sensors and Actuators B. 80 (2001), H. 2},
  isbn      = {0925-4005},
  pages     = {136 -- 140},
  year      = {2001},
  language  = {en}
}
@inproceedings{BegingPoghossianMlyneketal.2010,
  author    = {Beging, Stefan and Poghossian, Arshak and Mlynek, D. and Hataihimakul, S. and Pedraza, A. and Dhawan, S. and Laube, N. and Kleinen, L. and Baldsiefen, G. and Busch, H. and Sch{\"o}ning, Michael Josef},
  title     = {Ion-selective sensors for the determination of the risk of urinary stone formation},
  series = {Micro- and Nanosystems in biochemical diagnosis : Principles and applications},
  booktitle = {Micro- and Nanosystems in biochemical diagnosis : Principles and applications},
  address   = {Warsaw},
  pages     = {74 -- 80},
  year      = {2010},
  language  = {en}
}
@article{SchoeningSaukeSteffenetal.1995,
  author    = {Sch{\"o}ning, Michael Josef and Sauke, M. and Steffen, A. and Marso, M. (u.a.)},
  title     = {Ion-sensitive field-effect transistors with ultrathin Langmuir-Blodgett membranes},
  series = {Sensors and Actuators B. 27 (1995), H. 1-3},
  journal   = {Sensors and Actuators B. 27 (1995), H. 1-3},
  isbn      = {0925-4005},
  pages     = {325 -- 328},
  year      = {1995},
  language  = {en}
}
@article{LeschingerBeschAydinetal.2019,
  author    = {Leschinger, Tim and Besch, Katharina and Aydin, Cansu and Staat, Manfred and Scaal, Martin and M{\"u}ller, Lars Peter and Wegmann, Kilian},
  title     = {Irreparable rotator cuff tears: a biomechanical comparison of superior capsuloligamentous complex reconstruction techniques and an interposition graft technique},
  series = {The Orthopaedic Journal of Sports Medicine},
  volume    = {7},
  journal   = {The Orthopaedic Journal of Sports Medicine},
  number    = {8},
  doi       = {10.1177/2325967119864590},
  pages     = {1 -- 5},
  year      = {2019},
  language  = {en}
}
@article{MuellerVeggianBeuscherGono1978,
  author    = {M{\"u}ller-Veggian, Mattea and Beuscher, H. and Gono, Y.},
  title     = {Isomeric 10⁺ states in nuclei with N=78},
  series = {Proceedings of the International Conference on Nuclear Structure : Tokyo, Sept. 5 - 10, 1977 / ed. by T. Marumori. - Journal of the Physical Society of Japan ; Vol. 44, 1978 : Suppl.},
  journal   = {Proceedings of the International Conference on Nuclear Structure : Tokyo, Sept. 5 - 10, 1977 / ed. by T. Marumori. - Journal of the Physical Society of Japan ; Vol. 44, 1978 : Suppl.},
  publisher = {Physical Soc. of Japan},
  address   = {Tokyo},
  pages     = {861},
  year      = {1978},
  language  = {en}
}
@article{MuellerVeggianMorekBochevetal.1981,
  author    = {M{\"u}ller-Veggian, Mattea and Morek, T. and Bochev, B. and Kutsarova, T.},
  title     = {Isomeric state in ¹³⁴ La},
  series = {Annual report 1980 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: F. Gr{\"u}mmer. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 99)},
  journal   = {Annual report 1980 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: F. Gr{\"u}mmer. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 99)},
  publisher = {Kernforschungsanlage},
  address   = {J{\"u}lich},
  pages     = {47},
  year      = {1981},
  language  = {en}
}
@article{MuellerVeggianMorekBochevetal.1981,
  author    = {M{\"u}ller-Veggian, Mattea and Morek, T. and Bochev, B. and Kutsarova, T.},
  title     = {Isomeric state in ¹³⁶ La},
  series = {Annual report 1980 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: F. Gr{\"u}mmer. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 99)},
  journal   = {Annual report 1980 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: F. Gr{\"u}mmer. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 99)},
  publisher = {Kernforschungsanlage},
  address   = {J{\"u}lich},
  pages     = {48},
  year      = {1981},
  language  = {en}
}
@article{MuellerVeggianMorekBeuscheretal.1980,
  author    = {M{\"u}ller-Veggian, Mattea and Morek, T. and Beuscher, H. and Bochev, B.},
  title     = {Isomeric states in ¹³⁴ Ba},
  series = {Annual report 1979 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 72)},
  journal   = {Annual report 1979 / Kernforschungsanlage J{\"u}lich Institut f{\"u}r Kernphysik / Hrsg.: A. F{\"a}ssler. - (Spezielle Berichte der Kernforschungsanlage J{\"u}lich ; 72)},
  publisher = {Kernforschungsanlage},
  address   = {J{\"u}lich},
  pages     = {44},
  year      = {1980},
  language  = {en}
}
@article{MuellerVeggianMorekBeuscheretal.1980,
  author    = {M{\"u}ller-Veggian, Mattea and Morek, T. and Beuscher, H. and Bochev, B.},
  title     = {Isomeric states in ¹³⁴ Ba},
  series = {Zeitschrift f{\"u}r Physik / A, Hadrons and nuclei. 298 (1980), H. 4},
  journal   = {Zeitschrift f{\"u}r Physik / A, Hadrons and nuclei. 298 (1980), H. 4},
  isbn      = {1431-5831},
  pages     = {267 -- 271},
  year      = {1980},
  language  = {en}
}
@article{ZiemonsHerzogFeinendegen1990,
  author    = {Ziemons, Karl and Herzog, H. and Feinendegen, L. E.},
  title     = {Iterative image reconstruction with weighted pixel contribution to projection element},
  series = {European Journal of Nuclear Medicine},
  volume    = {16},
  journal   = {European Journal of Nuclear Medicine},
  number    = {7},
  isbn      = {1619-7089},
  pages     = {403 -- 403},
  year      = {1990},
  language  = {en}
}
@article{ZiemonsHerzogBosettietal.1992,
  author    = {Ziemons, Karl and Herzog, H. and Bosetti, P. and Feinendegen, L. E.},
  title     = {Iterative image reconstruction with weighted pixel contribution to projection elements},
  series = {European Journal of Nuclear Medicine},
  volume    = {19},
  journal   = {European Journal of Nuclear Medicine},
  number    = {8},
  isbn      = {1619-7089},
  pages     = {588 -- 588},
  year      = {1992},
  language  = {en}
}
@inproceedings{KetelhutGoellBraunsteinetal.2019,
  author    = {Ketelhut, Maike and G{\"o}ll, Fabian and Braunstein, Bjoern and Albracht, Kirsten and Abel, Dirk},
  title     = {Iterative learning control of an industrial robot for neuromuscular training},
  series = {2019 IEEE Conference on Control Technology and Applications},
  booktitle = {2019 IEEE Conference on Control Technology and Applications},
  publisher = {IEEE},
  address   = {New York},
  isbn      = {978-1-7281-2767-5 (ePub)},
  doi       = {10.1109/CCTA.2019.8920659},
  pages     = {7 Seiten},
  year      = {2019},
  abstract  = {Effective training requires high muscle forces potentially leading to training-induced injuries. Thus, continuous monitoring and controlling of the loadings applied to the musculoskeletal system along the motion trajectory is required. In this paper, a norm-optimal iterative learning control algorithm for the robot-assisted training is developed. The algorithm aims at minimizing the external knee joint moment, which is commonly used to quantify the loading of the medial compartment. To estimate the external knee joint moment, a musculoskeletal lower extremity model is implemented in OpenSim and coupled with a model of an industrial robot and a force plate mounted at its end-effector. The algorithm is tested in simulation for patients with varus, normal and valgus alignment of the knee. The results show that the algorithm is able to minimize the external knee joint moment in all three cases and converges after less than seven iterations.},
  language  = {en}
}
@article{Ziemons1987,
  author    = {Ziemons, Karl},
  title     = {Jet production and fragmentation properties in deep inelastic muon scattering},
  series = {Zeitschrift f{\"u}r Physik C : Particles and Fields},
  volume    = {36},
  journal   = {Zeitschrift f{\"u}r Physik C : Particles and Fields},
  number    = {4},
  isbn      = {0170-9739},
  pages     = {527 -- 543},
  year      = {1987},
  language  = {en}
}
@article{BerghoffLanskeSchultzeetal.1988,
  author    = {Berghoff, G. and Lanske, D. and Schultze, K. and Ziemons, Karl},
  title     = {Jets and QCD-effects in muon-nuclean scattering},
  series = {Verhandlungen der Deutschen Physikalischen Gesellschaft},
  volume    = {23},
  journal   = {Verhandlungen der Deutschen Physikalischen Gesellschaft},
  number    = {5},
  isbn      = {0420-0195},
  year      = {1988},
  language  = {en}
}
@inproceedings{BraunsteinGoldmannAlbrachtetal.2013,
  author    = {Braunstein, Bjoern and Goldmann, Jan-Peter and Albracht, Kirsten and Sanno, Maximilian and Willwacher, Steffen and Heinrich, Kai and Herrmann, Volker and Br{\"u}ggemann, Gert-Peter},
  title     = {Joint specific contribution of mechanical power and work during acceleration and top speed in elite sprinters},
  series = {31 International Conference on Biomechanics in Sports, Taipei, Taiwan, July 07 - July 22, 2013},
  booktitle = {31 International Conference on Biomechanics in Sports, Taipei, Taiwan, July 07 - July 22, 2013},
  issn      = {1999-4168},
  year      = {2013},
  language  = {en}
}
@inproceedings{GoldmannBraunsteinHeinrichetal.2015,
  author    = {Goldmann, Jan-Peter and Braunstein, Bjoern and Heinrich, Kai and Sanno, Maximilian and St{\"a}udle, Benjamin and Ritzdorf, Wolfgang and Br{\"u}ggemann, Gert-Peter and Albracht, Kirsten},
  title     = {Joint work of the take-off leg during elite high jump},
  series = {Proceedings of the 33th International Conference on Biomechanics in Sports (ISBS)},
  booktitle = {Proceedings of the 33th International Conference on Biomechanics in Sports (ISBS)},
  pages     = {3 S.},
  year      = {2015},
  language  = {en}
}
@article{MourzinaMaiPoghossianetal.2003,
  author    = {Mourzina, Y. and Mai, T. and Poghossian, Arshak and Ermolenko, Y. and Yoshinobu, T. and Vlasov, Y. and Iwasaki, H. and Sch{\"o}ning, Michael Josef},
  title     = {K+-selective field-effect sensors as transducers for bioelectronic applications},
  series = {Electrochimica Acta. 48 (2003), H. 20-22},
  journal   = {Electrochimica Acta. 48 (2003), H. 20-22},
  isbn      = {0013-4686},
  pages     = {3333 -- 3339},
  year      = {2003},
  language  = {en}
}
@article{Hillen1980,
  author    = {Hillen, Walter},
  title     = {K0 production in e+e\&\#8722; annihilations at 30 GeV center of mass energy. TASSO Collaboration},
  series = {Physics Letters B. 94 (1980), H. 1},
  journal   = {Physics Letters B. 94 (1980), H. 1},
  isbn      = {0370-2693},
  pages     = {91 -- 95},
  year      = {1980},
  language  = {en}
}
@article{EngelmannSimsekShalabyetal.2024,
  author    = {Engelmann, Ulrich M. and Simsek, Beril and Shalaby, Ahmed and Krause, Hans-Joachim},
  title     = {Key contributors to signal generation in frequency mixing magnetic detection (FMMD): an in silico study},
  series = {Sensors},
  volume    = {24},
  journal   = {Sensors},
  number    = {6},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {1424-8220},
  doi       = {10.3390/s24061945},
  pages     = {Artikel 1945},
  year      = {2024},
  abstract  = {Frequency mixing magnetic detection (FMMD) is a sensitive and selective technique to detect magnetic nanoparticles (MNPs) serving as probes for binding biological targets. Its principle relies on the nonlinear magnetic relaxation dynamics of a particle ensemble interacting with a dual frequency external magnetic field. In order to increase its sensitivity, lower its limit of detection and overall improve its applicability in biosensing, matching combinations of external field parameters and internal particle properties are being sought to advance FMMD. In this study, we systematically probe the aforementioned interaction with coupled N{\´e}el-Brownian dynamic relaxation simulations to examine how key MNP properties as well as applied field parameters affect the frequency mixing signal generation. It is found that the core size of MNPs dominates their nonlinear magnetic response, with the strongest contributions from the largest particles. The drive field amplitude dominates the shape of the field-dependent response, whereas effective anisotropy and hydrodynamic size of the particles only weakly influence the signal generation in FMMD. For tailoring the MNP properties and parameters of the setup towards optimal FMMD signal generation, our findings suggest choosing large particles of core sizes dc > 25 nm nm with narrow size distributions (σ < 0.1) to minimize the required drive field amplitude. This allows potential improvements of FMMD as a stand-alone application, as well as advances in magnetic particle imaging, hyperthermia and magnetic immunoassays.},
  language  = {en}
}
@book{Laack2000,
  author    = {Laack, Walter van},
  title     = {Key to Eternity / Walter van Laack. [Transl. by Anneliese Wolstenholme]},
  publisher = {van Laack},
  address   = {Aachen},
  isbn      = {978-3-8311-0344-7},
  pages     = {256 S.},
  year      = {2000},
  language  = {en}
}
@inproceedings{AbelBoninAlbrachtetal.2010,
  author    = {Abel, Thomas and Bonin, Dominik and Albracht, Kirsten and Zeller, Sebastian and Br{\"u}ggemann, Gert-Peter and Burkett, Brendan and Str{\"u}der, Heiko K.},
  title     = {Kinematic profile of the elite handcyclist},
  series = {28th International Conference on Biomechanics in Sports, Marquette, Michigan, USA, July 19 - 23, 2010},
  booktitle = {28th International Conference on Biomechanics in Sports, Marquette, Michigan, USA, July 19 - 23, 2010},
  issn      = {1999-4168},
  pages     = {140 -- 141},
  year      = {2010},
  language  = {en}
}
@article{MeyerGaalenLeschingeretal.2019,
  author    = {Meyer, Carolin and Gaalen, Kerstin van and Leschinger, Tim and Scheyerer, Max J. and Neiss, Wolfram F. and Staat, Manfred and M{\"u}ller, Lars P. and Wegmann, Kilian},
  title     = {Kyphoplasty of Osteoporotic Fractured Vertebrae: A Finite Element Analysis about Two Types of Cement},
  series = {BioMed Research International},
  journal   = {BioMed Research International},
  doi       = {10.1155/2019/9232813},
  pages     = {Article ID 9232813},
  year      = {2019},
  language  = {en}
}
@book{SchoeningPoghossian2018,
  author    = {Sch{\"o}ning, Michael Josef and Poghossian, Arshak},
  title     = {Label-free biosensing: advanced materials, devices and applications},
  publisher = {Springer},
  address   = {Cham},
  isbn      = {978-3-319-75219-8},
  pages     = {xii, 480 Seiten ; Illustrationen, Diagramme},
  year      = {2018},
  language  = {en}
}
@article{PoghossianIngebrandtAbouzaretal.2007,
  author    = {Poghossian, Arshak and Ingebrandt, S. and Abouzar, Maryam H. and Sch{\"o}ning, Michael Josef},
  title     = {Label-free detection of charged macromolecules by using a field-effect-based sensor platform: Experiments and possible mechanisms of signal generation},
  series = {Applied Physics A: Materials Science \& Processing. 87 (2007), H. 3},
  journal   = {Applied Physics A: Materials Science \& Processing. 87 (2007), H. 3},
  isbn      = {0947-8396},
  pages     = {517 -- 524},
  year      = {2007},
  language  = {en}
}
@article{BronderWuPoghossianetal.2014,
  author    = {Bronder, Thomas and Wu, Chunsheng and Poghossian, Arshak and Werner, Frederik and Keusgen, M. and Sch{\"o}ning, Michael Josef},
  title     = {Label-free detection of DNA hybridization with light-addressable potentiometric sensors: comparison of various DNA-immobilization strategies},
  series = {Procedia Engineering},
  volume    = {87},
  journal   = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2014.11.647},
  pages     = {755 -- 758},
  year      = {2014},
  abstract  = {Light-addressable potentiometric sensors (LAPS) consisting of a p-Si-SiO2 and p-Si-SiO2-Au structure, respectively, have been tested for a label-free electrical detection of DNA (deoxyribonucleic acid) hybridization. Three different strategies for immobilizing single-stranded probe DNA (ssDNA) molecules on a LAPS surface have been studied and compared: (a) immobilization of thiol-modified ssDNA on the patterned Au surface via gold-thiol bond, (b) covalent immobilization of amino-modified ssDNA onto the SiO2 surface functionalized with 3-aminopropyltriethoxysilane and (c) layer-by-layer adsorption of negatively charged ssDNA on a positively charged weak polyelectrolyte layer of poly(allylamine hydrochloride).},
  language  = {en}
}
@article{WuBronderPoghossianetal.2015,
  author    = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Werner, Frederik and Sch{\"o}ning, Michael Josef},
  title     = {Label-free detection of DNA using light-addressable potentiometric sensor modified with a positively charged polyelectrolyte layer},
  series = {Nanoscale},
  volume    = {14},
  journal   = {Nanoscale},
  number    = {7},
  publisher = {Royal Society of Chemistry (RSC)},
  address   = {Cambridge},
  doi       = {10.1039/C4NR07225A},
  pages     = {6143 -- 6150},
  year      = {2015},
  abstract  = {A multi-spot (16 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al-p-Si-SiO2 structure modified with a weak polyelectrolyte layer of PAH (poly(allylamine hydrochloride)) was applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. To achieve a preferentially flat orientation of DNA strands and thus, to reduce the distance between the DNA charge and MLAPS surface, the negatively charged probe single-stranded DNAs (ssDNA) were electrostatically adsorbed onto the positively charged PAH layer using a simple layer-by-layer (LbL) technique. In this way, more DNA charge can be positioned within the Debye length, yielding a higher sensor signal. The surface potential changes in each spot induced due to the surface modification steps (PAH adsorption, probe ssDNA immobilization, hybridization with complementary target DNA (cDNA), non-specific adsorption of mismatched ssDNA) were determined from the shifts of photocurrent-voltage curves along the voltage axis. A high sensor signal of 83 mV was registered after immobilization of probe ssDNA onto the PAH layer. The hybridization signal increases from 5 mV to 32 mV with increasing the concentration of cDNA from 0.1 nM to 5 μM. In contrast, a small signal of 5 mV was recorded in the case of non-specific adsorption of fully mismatched ssDNA (5 μM). The obtained results demonstrate the potential of the MLAPS in combination with the simple and rapid LbL immobilization technique as a promising platform for the future development of multi-spot light-addressable label-free DNA chips with direct electrical readout.},
  language  = {en}
}
@article{BronderPoghossianKeusgenetal.2017,
  author    = {Bronder, Thomas and Poghossian, Arshak and Keusgen, Michael and Sch{\"o}ning, Michael Josef},
  title     = {Label-free detection of double-stranded DNA molecules with polyelectrolyte-modified capacitive field-effect sensors},
  series = {tm - Technisches Messen},
  volume    = {84},
  journal   = {tm - Technisches Messen},
  number    = {10},
  publisher = {De Gruyter},
  address   = {Oldenbourg},
  doi       = {10.1515/teme-2017-0015},
  pages     = {628 -- 634},
  year      = {2017},
  abstract  = {In this study, polyelectrolyte-modified field-effect-based electrolyte-insulator-semiconductor (EIS) devices have been used for the label-free electrical detection of double-stranded deoxyribonucleic acid (dsDNA)molecules. The sensor-chip functionalization with a positively charged polyelectrolyte layer provides the possibility of direct adsorptive binding of negatively charged target DNA oligonucleotides onto theSiO2-chip surface.EIS sensors can be utilized as a tool to detect surface-charge changes; the electrostatic adsorption of oligonucleotides onto the polyelectrolyte layer leads to a measureable surface-potential change. Signals of 39mV have been recorded after the incubation with the oligonucleotide solution. Besides the electrochemical experiments, the successful adsorption of dsDNA onto the polyelectrolyte layer has been verified via fluorescence microscopy. The presented results demonstrate that the signal recording of EISchips, which are modified with a polyelectrolyte layer, canbe used as a favorable approach for a fast, cheap and simple detection method for dsDNA.},
  language  = {en}
}
@article{IngebrandtHanNakamuraetal.2007,
  author    = {Ingebrandt, S. and Han, Y. and Nakamura, F. and Poghossian, Arshak and Sch{\"o}ning, Michael Josef and Offenh{\"a}usser, A.},
  title     = {Label-free detection of single nucleotide polymorphisms utilizing the differential transfer function of field-effect transistors},
  series = {Biosensors and Bioelectronics. 22 (2007), H. 12},
  journal   = {Biosensors and Bioelectronics. 22 (2007), H. 12},
  isbn      = {0956-5663},
  pages     = {2834 -- 2840},
  year      = {2007},
  language  = {en}
}
@phdthesis{Bronder2020,
  author    = {Bronder, Thomas},
  title     = {Label-free detection of tuberculosis DNA with capacitive field-effect biosensors},
  publisher = {Philipps-Universit{\"a}t Marburg},
  address   = {Marburg},
  doi       = {10.17192/z2021.0056},
  pages     = {X, 162 S},
  year      = {2020},
  language  = {en}
}
@article{SchoeningBronderWuetal.2017,
  author    = {Sch{\"o}ning, Michael Josef and Bronder, Thomas and Wu, Chunsheng and Scheja, Sabrina and Jessing, Max and Metzger-Boddien, Christoph and Keusgen, Michael and Poghossian, Arshak},
  title     = {Label-Free DNA Detection with Capacitive Field-Effect Devices—Challenges and Opportunities},
  series = {Proceedings},
  volume    = {1},
  journal   = {Proceedings},
  number    = {8},
  publisher = {MDPI},
  address   = {Basel},
  issn      = {2504-3900},
  doi       = {10.3390/proceedings1080719},
  pages     = {Artikel 719},
  year      = {2017},
  abstract  = {Field-effect EIS (electrolyte-insulator-semiconductor) sensors modified with a positively charged weak polyelectrolyte layer have been applied for the electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge. The EIS sensors are able to detect the existence of target DNA amplicons in PCR (polymerase chain reaction) samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process. Due to their miniaturized setup, compatibility with advanced micro- and nanotechnologies, and ability to detect biomolecules by their intrinsic molecular charge, those sensors can serve as possible platform for the development of label-free DNA chips. Possible application fields as well as challenges and limitations will be discussed.},
  language  = {en}
}
@article{AbouzarPedrazaSchoeningetal.2010,
  author    = {Abouzar, Maryam H. and Pedraza, A. M. and Sch{\"o}ning, Michael Josef and Poghossian, Arshak},
  title     = {Label-free DNA hybridization and denaturation detection by means of field-effect nanoplate SOI capacitors functionalized with gold nanoparticles},
  series = {Procedia Engineering. 5 (2010)},
  journal   = {Procedia Engineering. 5 (2010)},
  isbn      = {1877-7058},
  pages     = {918 -- 921},
  year      = {2010},
  language  = {en}
}
@article{AbouzarPoghossianCherstvyetal.2012,
  author    = {Abouzar, Maryam H. and Poghossian, Arshak and Cherstvy, Andrey G. and Pedraza, Angela M. and Ingebrandt, Sven and Sch{\"o}ning, Michael Josef},
  title     = {Label-free electrical detection of DNA by means of field-effect nanoplate capacitors: Experiments and modeling},
  series = {Physica Status Solidi (a)},
  volume    = {209},
  journal   = {Physica Status Solidi (a)},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201100710},
  pages     = {925 -- 934},
  year      = {2012},
  abstract  = {Label-free electrical detection of consecutive deoxyribonucleic acid (DNA) hybridization/denaturation by means of an array of individually addressable field-effect-based nanoplate silicon-on-insulator (SOI) capacitors modified with gold nanoparticles (Au-NP) is investigated. The proposed device detects charge changes on Au-NP/DNA hybrids induced by the hybridization or denaturation event. DNA hybridization was performed in a high ionic-strength solution to provide a high hybridization efficiency. On the other hand, to reduce the screening of the DNA charge by counter ions and to achieve a high sensitivity, the sensor signal induced by the hybridization and denaturation events was measured in a low ionic-strength solution. High sensor signals of about 120, 90, and 80 mV were registered after the DNA hybridization, denaturation, and re-hybridization events, respectively. Fluorescence microscopy has been applied as reference method to verify the DNA immobilization, hybridization, and denaturation processes. An electrostatic charge-plane model for potential changes at the gate surface of a nanoplate field-effect sensor induced by the DNA hybridization has been developed taking into account both the Debye length and the distance of the DNA charge from the gate surface.},
  language  = {en}
}
@article{WuBronderPoghossianetal.2014,
  author    = {Wu, Chunsheng and Bronder, Thomas and Poghossian, Arshak and Werner, Frederik and B{\"a}cker, Matthias and Sch{\"o}ning, Michael Josef},
  title     = {Label-free electrical detection of DNA with a multi-spot LAPS: First step towards light-addressable DNA chips},
  series = {Physica status solidi A : Applications and materials science},
  volume    = {211},
  journal   = {Physica status solidi A : Applications and materials science},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)},
  doi       = {10.1002/pssa.201330442},
  pages     = {1423 -- 1428},
  year      = {2014},
  abstract  = {A multi-spot (4 × 4 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al-p-Si-SiO2 structure has been applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. Single-stranded probe ssDNA molecules (20 bases) were covalently immobilized onto the silanized SiO2 gate surface. The unspecific adsorption of mismatch ssDNA on the MLAPS gate surface was blocked by bovine serum albumin molecules. To reduce the screening effect and to achieve a high sensor signal, the measurements were performed in a low ionic-strength solution. The photocurrent-voltage (I-V) curves were simultaneously recorded on all 16 spots after each surface functionalization step. Large shifts of I-V curves of 25 mV were registered after the DNA immobilization and hybridization event. In contrast, a small potential shift (∼5 mV) was observed in case of mismatch ssDNA, revealing good specificity of the sensor. The obtained results demonstrate the potential of the MLAPS as promising transducer platform for the multi-spot label-free electrical detection of DNA molecules by their intrinsic molecular charge.},
  language  = {en}
}
@inproceedings{PoghossianBronderSchejaetal.2016,
  author    = {Poghossian, Arshak and Bronder, Thomas and Scheja, S. and Wu, Chunsheng and Metzger-Boddien, C. and Keusgen, M. and Sch{\"o}ning, Michael Josef},
  title     = {Label-free Electrostatic Detection of DNA Amplification by PCR Using Capacitive Field-effect Devices},
  series = {Procedia Engineering},
  volume    = {Vol. 168},
  booktitle = {Procedia Engineering},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {1877-7058},
  doi       = {10.1016/j.proeng.2016.11.512},
  pages     = {514 -- 517},
  year      = {2016},
  abstract  = {A capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensor modified with a positively charged weak polyelectrolyte of poly(allylamine hydrochloride) (PAH)/single-stranded probe DNA (ssDNA) bilayer has been used for a label-free electrostatic detection of pathogen-specific DNA amplification via polymerase chain reaction (PCR). The sensor is able to distinguish between positive and negative PCR solutions, to detect the existence of target DNA amplicons in PCR samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process.},
  language  = {en}
}
@inproceedings{PoghossianBronderWuetal.2015,
  author    = {Poghossian, Arshak and Bronder, Thomas and Wu, Chunsheng and Sch{\"o}ning, Michael Josef},
  title     = {Label-free sensing of biomolecules by their intrinsic molecular charge using field-effect devices},
  series = {Semiconductor Micro- and Nanoelectonics : Proceedings of the tenth international conference, Yerevan, Armenia, September 11-13},
  booktitle = {Semiconductor Micro- and Nanoelectonics : Proceedings of the tenth international conference, Yerevan, Armenia, September 11-13},
  isbn      = {978-5-8084-1991-9},
  pages     = {61 -- 63},
  year      = {2015},
  language  = {en}
}
@article{PoghossianSchoening2014,
  author    = {Poghossian, Arshak and Sch{\"o}ning, Michael Josef},
  title     = {Label-free sensing of biomolecules with field-effect devices for clinical applications},
  series = {Electroanalysis},
  volume    = {26},
  journal   = {Electroanalysis},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-4109 (E-Journal); 1040-0397 (Print)},
  doi       = {10.1002/elan.201400073},
  pages     = {1197 -- 1213},
  year      = {2014},
  abstract  = {Among the variety of transducer concepts proposed for label-free detection of biomolecules, the semiconductor field-effect device (FED) is one of the most attractive platforms. As medical techniques continue to progress towards diagnostic and therapies based on biomarkers, the ability of FEDs for a label-free, fast and real-time detection of multiple pathogenic and physiologically relevant molecules with high specificity and sensitivity offers very promising prospects for their application in point-of-care and personalized medicine for an early diagnosis and treatment of diseases. The presented paper reviews recent advances and current trends in research and development of different FEDs for label-free, direct electrical detection of charged biomolecules by their intrinsic molecular charge. The authors are mainly focusing on the detection of the DNA hybridization event, antibody-antigen affinity reaction as well as clinically relevant biomolecules such as cardiac and cancer biomarkers.},
  language  = {en}
}