@techreport{NaglKraft2004,
  author    = {Nagl, Manfred and Kraft, Bodo},
  title     = {Graphbasierte Werkzeuge zur Unterst{\"u}tzung des konzeptuellen Geb{\"a}ude-Entwurfs : Bericht {\"u}ber den 2. F{\"o}rderzeitraum des Schwerpunktprogramms : DFG-Schwerpunktprogramm 1103 : Vernetzt-kooperative Planungsprozesse im Konstruktiven Ingenieurbau. - Auch unter dem Titel: Neue Software-Werkzeuge zur Unterst{\"u}tzung des konzeptuellen Geb{\"a}udeentwurfs},
  year      = {2004},
  abstract  = {Der konstruktive Entwurf wird in derzeitigen CAD-Systemen gut unterst{\"u}tzt, nicht aber der konzeptuelle Geb{\"a}ude-Entwurf. Dieser abstrahiert von konstruktiven Elementen wie Linie, Wand oder Decke, um auf die Konzepte, d.h. die eigentlichen Funktionen, heraus zu arbeiten. Diese abstraktere, funktionale Sichtweise auf ein Geb{\"a}ude ist w{\"a}hrend der fr{\"u}hen Entwurfsphase essentiell, um Struktur und Organisation des gesamten Geb{\"a}udes zu erfassen. Bereits in dieser Phase muss Fachwissen (z. B. rechtliche, {\"o}konomische und technische Bestimmungen) ber{\"u}cksichtigt werden. Im Rahmen des vorliegenden Projekts werden Software-Werkzeuge integriert in industrielle CAD-Systeme entwickelt, die den konzeptuellen Geb{\"a}ude-Entwurf erm{\"o}glichen und diesen gegen Fachwissen pr{\"u}fen. Das Projekt ist in zwei Teile gegliedert. Im Top-Down-Ansatz werden Datenstrukturen und Methoden zur Strukturierung, Repr{\"a}sentation und Evaluation von geb{\"a}udespezifischem Fachwissen erarbeitet. Dieser Teil baut auf den graphbasierten Werkzeugen PROGRES und UPGRADE des Lehrstuhls auf. Der Bottom-Up-Ansatz ist industriell orientiert und hat zum Ziel, das kommerzielle CAD-System ArchiCAD zu erweitern. Hierbei soll der fr{\"u}he, konzeptuelle Geb{\"a}ude-Entwurf in einem CAD-System erm{\"o}glicht werden. Der Entwurf kann dar{\"u}ber hinaus gegen das definierte Fachwissen gepr{\"u}ft werden. Im Rahmen des graphbasierten Top-Down-Ansatzes wurde zun{\"a}chst eine neue Spezifikationsmethode f{\"u}r die Sprache PROGRES entwickelt. Das PROGRES-System erlaubt die Spezifikation von Werkzeugen in deklarativer Form. {\"U}blicherweise wird dom{\"a}nenspezifisches Fachwissen in der PROGRES-Spezifikation codiert, das daraus generierte visuelle Werkzeug stellt dann die entsprechende Funktionalit{\"a}t zur Verf{\"u}gung. Mit dieser Methode sind am Lehrstuhl f{\"u}r Informatik III Werkzeuge f{\"u}r verschie-dene Anwendungsdom{\"a}nen entstanden. In unserem Fall versetzen wir einen Dom{\"a}nen-Experten, z. B. einen erfahrenen Architekten, in die Lage, Fachwissen zur Laufzeit einzugeben, dieses zu evaluieren, abzu{\"a}ndern oder zu erg{\"a}nzen. Im Rahmen der bisherigen Arbeit wurde dazu eine parametrisierte PROGRES-Spezifikation und zwei darauf aufbauende Werkzeuge entwickelt, welche die dynamische Eingabe von geb{\"a}ude-technisch relevantem Fachwissen erlauben und einen graphbasierten, konzeptuellen Geb{\"a}ude-Entwurf erm{\"o}glichen. In diesem konzeptuellen Geb{\"a}ude-Entwurf wird von Raumgr{\"o}ßen und Positionen abstrahiert, um die funktionale Struktur eines Geb{\"a}udes zu beschreiben. Das Fachwissen kann von einem Architekten visuell definiert werden. Es k{\"o}nnen semantische Einheiten, im einfachsten Fall R{\"a}ume, nach verschiedenen Kriterien kategorisiert und klassifiziert werden. Mit Hilfe von Attributen und Relationen k{\"o}nnen die semantischen Einheiten pr{\"a}ziser beschrieben und in Beziehung zueinander gesetzt werden. Die in PROGRES spezifizierten Konsistenz-Analysen erlauben die Pr{\"u}fung eines graphbasierten konzeptuellen Geb{\"a}ude-Entwurfs gegen das dynamisch eingef{\"u}gte Fachwissen. Im zweiten Teil des Forschungsprojekts, dem Bottom-Up-Ansatz, wird das CAD-System ArchiCAD erweitert, um den integrierten konzeptuellen Geb{\"a}ude-Entwurf zu erm{\"o}glichen. Der Architekt erh{\"a}lt dazu neue Entwurfselemente, die Raumobjekte, welche die relevanten semantischen Einheiten w{\"a}hrend der fr{\"u}hen Entwurfsphase repr{\"a}sentieren. Mit Hilfe der Raumobjekte kann der Architekt in ArchiCAD den Grundriss und das Raumprogramm eines Geb{\"a}udes entwerfen, ohne von konstruktiven Details in seiner Kreativit{\"a}t eingeschr{\"a}nkt zu werden. Die Arbeitsweise mit Raumobjekten entspricht dem informellen konzeptuellen Entwurf auf einer Papierskizze und ist daher f{\"u}r den Architekten intuitiv und einfach zu verwenden. Durch die Integration in ArchiCAD ergibt sich eine weitere Unterst{\"u}tzung: Das im Top-Down-Ansatz spezifizierte Fach-wissen wird verwendet, um den konzeptuellen Geb{\"a}ude-Entwurf des Architekten auf Regelverletzungen zu {\"u}berpr{\"u}fen. Entwurfsfehler werden angezeigt. Zum Abschluss des konzeptuellen Geb{\"a}ude-Entwurfs mit Raumobjekten wird durch ein weiteres neu entwickeltes Werkzeug eine initiale Wandstruktur automatisch erzeugt, die als Grundlage f{\"u}r die folgenden konstruktiven Entwurfsphasen dient. Alle beschriebenen Erwei-terungen sind in ArchiCAD integriert, sie sind f{\"u}r den Architekten daher leicht zu erlernen und einfach zu bedienen.},
  subject      = {CAD},
  language  = {de}
}
@inproceedings{KraftRetkowitz2006,
  author    = {Kraft, Bodo and Retkowitz, Daniel},
  title     = {Graph Transformations for Dynamic Knowledge Processing},
  year      = {2006},
  abstract  = {In: Proceedings of the 39th Annual Hawaii International Conference on System Sciences, 2006. HICSS '06 http://dx.doi.org/10.1109/HICSS.2006.200 The conceptual design phase at the beginning of the building construction process is not adequately supported by any CAD-tool. Conceptual design support needs regarding two aspects: first, the architect must be able to develop conceptual sketches that provide abstraction from constructive details. Second, conceptually relevant knowledge should be available to check these conceptual sketches. The paper deals with knowledge to formalize for conceptual design. To enable domain experts formalizing knowledge, a graph-based specification is presented that allows the development of a domain ontology and design rules specific for one class of buildings at runtime. The provided tool support illustrates the introduced concepts and demonstrates the consistency analysis between knowledge and conceptual design.},
  subject      = {CAD},
  language  = {de}
}
@inproceedings{KraftMeyerNagl2002,
  author    = {Kraft, Bodo and Meyer, Oliver and Nagl, Manfred},
  title     = {Graph technology support for conceptual design in civil engineering},
  isbn      = {3-18-318004-9},
  year      = {2002},
  abstract  = {In: Advances in intelligent computing in engineering : proceedings of the 9.International EG-ICE Workshop ; Darmstadt, (01 - 03 August) 2002 / Martina Schnellenbach-Held ... (eds.) . - D{\"u}sseldorf: VDI-Verl., 2002 .- Fortschritt-Berichte VDI, Reihe 4, Bauingenieurwesen ; 180 ; S. 1-35 The paper describes a novel way to support conceptual design in civil engineering. The designer uses semantical tools guaranteeing certain internal structures of the design result but also the fulfillment of various constraints. Two different approaches and corresponding tools are discussed: (a) Visually specified tools with automatic code generation to determine a design structure as well as fixing various constraints a design has to obey. These tools are also valuable for design knowledge specialist. (b) Extensions of existing CAD tools to provide semantical knowledge to be used by an architect. It is sketched how these different tools can be combined in the future. The main part of the paper discusses the concepts and realization of two prototypes following the two above approaches. The paper especially discusses that specific graphs and the specification of their structure are useful for both tool realization projects.},
  subject      = {CAD},
  language  = {en}
}
@article{RichterBraunsteinStaeudleetal.2021,
  author    = {Richter, Charlotte and Braunstein, Bj{\"o}rn and St{\"a}udle, Benjamin and Attias, Julia and S{\"u}ss, Alexander and Weber, Tobias and Mileva, Katya N. and Rittweger, J{\"o}rn and Green, David A. and Albracht, Kirsten},
  title     = {Gastrocnemius medialis contractile behavior during running differs between simulated Lunar and Martian gravities},
  series = {Scientific reports},
  volume    = {11},
  journal   = {Scientific reports},
  number    = {Article number: 22555},
  publisher = {Springer Nature},
  address   = {London},
  issn      = {2045-2322},
  doi       = {10.1038/s41598-021-00527-9},
  pages     = {13 Seiten},
  year      = {2021},
  abstract  = {The international partnership of space agencies has agreed to proceed forward to the Moon sustainably. Activities on the Lunar surface (0.16 g) will allow crewmembers to advance the exploration skills needed when expanding human presence to Mars (0.38 g). Whilst data from actual hypogravity activities are limited to the Apollo missions, simulation studies have indicated that ground reaction forces, mechanical work, muscle activation, and joint angles decrease with declining gravity level. However, these alterations in locomotion biomechanics do not necessarily scale to the gravity level, the reduction in gastrocnemius medialis activation even appears to level off around 0.2 g, while muscle activation pattern remains similar. Thus, it is difficult to predict whether gastrocnemius medialis contractile behavior during running on Moon will basically be the same as on Mars. Therefore, this study investigated lower limb joint kinematics and gastrocnemius medialis behavior during running at 1 g, simulated Martian gravity, and simulated Lunar gravity on the vertical treadmill facility. The results indicate that hypogravity-induced alterations in joint kinematics and contractile behavior still persist between simulated running on the Moon and Mars. This contrasts with the concept of a ceiling effect and should be carefully considered when evaluating exercise prescriptions and the transferability of locomotion practiced in Lunar gravity to Martian gravity.},
  language  = {en}
}
@inproceedings{WagnerKohlFroebaetal.2006,
  author    = {Wagner, Thorsten and Kohl, Claus-Dieter and Fr{\"o}ba, Michael and Tiemann, Michael},
  title     = {Gas sensing properties of ordered mesoporous SnO2},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-1422},
  year      = {2006},
  abstract  = {We report on the synthesis and CO gas-sensing properties of mesoporous tin(IV) oxides (SnO2). For the synthesis cetyltrimethylammonium bromide (CTABr) was used as a structure-directing agent; the resulting SnO2 powders were applied as films to commercially available sensor substrates by drop coating. Nitrogen physisorption shows specific surface areas up to 160 m2·g-1 and mean pore diameters of about 4 nm, as verified by TEM. The film conductance was measured in dependence on the CO concentration in humid synthetic air at a constant temperature of 300 °C. The sensors show a high sensitivity at low CO concentrations and turn out to be largely insensitive towards changes in the relative humidity. We compare the materials with commercially available SnO2-based sensors.},
  subject      = {Biosensor},
  language  = {en}
}
@inproceedings{StaatBallmann1989,
  author    = {Staat, Manfred and Ballmann, J.},
  title     = {Fundamental aspects of numerical methods for the propagation of multi-dimensional nonlinear waves in solids},
  series = {Nonlinear hyperbolic equations : theory, computations methods, and applications ; proceedings of the 2nd International Conference on Nonlinear Hyperbolic Problems, Aachen},
  booktitle = {Nonlinear hyperbolic equations : theory, computations methods, and applications ; proceedings of the 2nd International Conference on Nonlinear Hyperbolic Problems, Aachen},
  pages     = {574 -- 588},
  year      = {1989},
  abstract  = {The nonlinear scalar constitutive equations of gases lead to a change in sound speed from point to point as would be found in linear inhomogeneous (and time dependent) media. The nonlinear tensor constitutive equations of solids introduce the additional local effect of solution dependent anisotropy. The speed of a wave passing through a point changes with propagation direction and its rays are inclined to the front. It is an open question whether the widely used operator splitting techniques achieve a dimensional splitting with physically reasonable results for these multi-dimensional problems. May be this is the main reason why the theoretical and numerical investigations of multi-dimensional wave propagation in nonlinear solids are so far behind gas dynamics. We hope to promote the subject a little by a discussion of some fundamental aspects of the solution of the equations of nonlinear elastodynamics. We use methods of characteristics because they only integrate mathematically exact equations which have a direct physical interpretation.},
  subject      = {Nichtlineare Welle},
  language  = {en}
}
@inproceedings{PoghossianSchumacherKloocketal.2006,
  author    = {Poghossian, Arshak and Schumacher, Kerstin and Kloock, Joachim P. and Rosenkranz, Christian and Schultze, Joachim W. and M{\"u}ller-Veggian, Mattea and Sch{\"o}ning, Michael Josef},
  title     = {Functional testing and characterisation of ISFETs on wafer level by means of a micro-droplet cell},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-1259},
  year      = {2006},
  abstract  = {A wafer-level functionality testing and characterisation system for ISFETs (ionsensitive field-effect transistor) is realised by means of integration of a specifically designed capillary electrochemical micro-droplet cell into a commercial wafer prober-station. The developed system allows the identification and selection of "good" ISFETs at the earliest stage and to avoid expensive bonding, encapsulation and packaging processes for nonfunctioning ISFETs and thus, to decrease costs, which are wasted for bad dies. The developed system is also feasible for wafer-level characterisation of ISFETs in terms of sensitivity, hysteresis and response time. Additionally, the system might be also utilised for wafer-level testing of further electrochemical sensors.},
  subject      = {Biosensor},
  language  = {en}
}
@inproceedings{TranStaatKreissig2007,
  author    = {Tran, Thanh Ngoc and Staat, Manfred and Kreißig, R.},
  title     = {Finite element shakedown and limit reliability analysis of thin shells},
  year      = {2007},
  abstract  = {A procedure for the evaluation of the failure probability of elastic-plastic thin shell structures is presented. The procedure involves a deterministic limit and shakedown analysis for each probabilistic iteration which is based on the kinematical approach and the use the exact Ilyushin yield surface. Based on a direct definition of the limit state function, the non-linear problems may be efficiently solved by using the First and Second Order Reliabiblity Methods (Form/SORM). This direct approach reduces considerably the necessary knowledge of uncertain technological input data, computing costs and the numerical error. In: Computational plasticity / ed. by Eugenio Onate. Dordrecht: Springer 2007. VII, 265 S. (Computational Methods in Applied Sciences ; 7) (COMPLAS IX. Part 1 . International Center for Numerical Methods in Engineering (CIMNE)). ISBN 978-1-402-06576-7 S. 186-189},
  subject      = {Finite-Elemente-Methode},
  language  = {en}
}
@inproceedings{DigelDemirciTrzewiketal.2004,
  author    = {Digel, Ilya and Demirci, Taylan and Trzewik, J{\"u}rgen and Linder, Peter and Temiz Artmann, Ayseg{\"u}l},
  title     = {Fibroblast response to mechanical stress: role of the adhesion substrate : [abstract]},
  year      = {2004},
  abstract  = {Mechanical stimulation of the cells resulted in evident changes in the cell morphology, protein composition and gene expression. Microscopically, additional formation of stress fibers accompanied by cell re-arrangements in a monolayer was observed. Also, significant activation of p53 gene was revealed as compared to control. Interestingly, the use of CellTech membrane coating induced cell death after mechanical stress had been applied. Such an effect was not detected when fibronectin had been used as an adhesion substrate.},
  subject      = {Fibroblast},
  language  = {en}
}
@inproceedings{FoersterStockMontanarietal.2006,
  author    = {F{\"o}rster, Arnold and Stock, J{\"u}rgen and Montanari, Simone and Lepsa, Mihail Ion and L{\"u}th, Hans},
  title     = {Fabrication and characterisation of GaAs Gunn Diode Chips for applications at 77 GHz in automotive industry},
  url       = {http://nbn-resolving.de/urn:nbn:de:hbz:a96-opus-1462},
  year      = {2006},
  abstract  = {GaAs-based Gunn diodes with graded AlGaAs hot electron injector heterostructures have been developed under the special needs in automotive applications. The fabrication of the Gunn diode chips was based on total substrate removal and processing of integrated Au heat sinks. Especially, the thermal and RF behavior of the diodes have been analyzed by DC, impedance and S-parameter measurements. The electrical investigations have revealed the functionality of the hot electron injector. An optimized layer structure could fulfill the requirements in adaptive cruise control (ACC) systems at 77 GHz with typical output power between 50 and 90 mW.},
  subject      = {Biosensor},
  language  = {en}
}
@article{GorissenStaatLaack2012,
  author    = {Gorissen, P. and Staat, Manfred and Laack, Walter van},
  title     = {Experimentelle Kraftmessungen als Beitrag zur Wirksamkeitsbeurteilung von Schienbeinschonern im Fußballsport},
  series = {OUP Zeitschrift f{\"u}r die orthop{\"a}dische und unfallchirurgische Praxis},
  volume    = {1},
  journal   = {OUP Zeitschrift f{\"u}r die orthop{\"a}dische und unfallchirurgische Praxis},
  number    = {1},
  publisher = {Deutscher {\"A}rzte-Verlag},
  address   = {K{\"o}ln},
  issn      = {2193-5785},
  doi       = {10.3238/oup.2012.0010-0015},
  pages     = {10 -- 15},
  year      = {2012},
  abstract  = {Diese Studie besch{\"a}ftigte sich mit der D{\"a}mpfungswirkung von Schienbeinschonern, wie sie beim Fußball zum Einsatz kommen. Sie wurde mit Hilfe eines Pendelhammers durchgef{\"u}hrt, der verschiedene Aufschlagkr{\"a}fte auf die Schoner erm{\"o}glichte. Dabei wurde deutlich, dass Schienbeinschoner die beste Wirkung bei Maximalkr{\"a}ften unterhalb von 5kN erreichen k{\"o}nnen, dass bei gr{\"o}ßerer Belastung allerdings Verbesserungsbedarf besteht. Hierf{\"u}r konnte, u.a. durch den Einsatz neuer Materialien, ein guter Ansatzpunkt im „ad{\"a}quaten Zusammenspiel von Schale und Polsterung" der Schoner gefunden werden. Die Untersuchung hat weiterhin gezeigt, dass zumindest teilweise eine deutliche Verbesserung der D{\"a}mpfungswirkung der Schienbeinschoner in den letzten Jahren erreicht werden konnte.},
  subject      = {Fußball},
  language  = {de}
}
@inproceedings{TranNovacekTolbaetal.2011,
  author    = {Tran, Thanh Ngoc and Novacek, V. and Tolba, R. and Klinge, U. and Turquier, F. and Staat, Manfred},
  title     = {Experimental and Computational approach to study colorectal anastomosis. ISB2011, Proceedings of the XXIII Congress of the International Society of Biomechanics, Brussels, Belgium, July 3-7, 2011},
  year      = {2011},
  abstract  = {Summary: This paper presents a methodology to study and understand the mechanics of stapled anastomotic behaviors by combining empirical experimentation and finite element analysis. Performance of stapled anastomosis is studied in terms of leakage and numerical results which are compared to in vitro experiments performed on fresh porcine tissue. Results suggest that leaks occur between the tissue and staple legs penetrating through the tissue.},
  subject      = {Anastomose},
  language  = {en}
}
@inproceedings{FrotscherKochRaatschenetal.2014,
  author    = {Frotscher, Ralf and Koch, Jan-Peter and Raatschen, Hans-J{\"u}rgen and Staat, Manfred},
  title     = {Evaluation of a computational model for drug action on cardiac tissue},
  series = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20 - 25, 2014, Barcelona},
  booktitle = {11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20 - 25, 2014, Barcelona},
  editor    = {Onate, E.},
  organization    = {World Congress on Computational Mechanics <11, 2014, Barcelona>},
  pages     = {1 -- 12},
  year      = {2014},
  language  = {en}
}
@article{AlexyukBogoyavlenskiyAlexyuketal.2021,
  author    = {Alexyuk, Madina and Bogoyavlenskiy, Andrey and Alexyuk, Pavel and Moldakhanov, Yergali and Berezin, Vladimir and Digel, Ilya},
  title     = {Epipelagic microbiome of the Small Aral Sea: Metagenomic structure and ecological diversity},
  series = {MicrobiologyOpen},
  volume    = {10},
  journal   = {MicrobiologyOpen},
  number    = {1},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {2045-8827},
  doi       = {10.1002/mbo3.1142},
  pages     = {1 -- 10},
  year      = {2021},
  abstract  = {Microbial diversity studies regarding the aquatic communities that experienced or are experiencing environmental problems are essential for the comprehension of the remediation dynamics. In this pilot study, we present data on the phylogenetic and ecological structure of microorganisms from epipelagic water samples collected in the Small Aral Sea (SAS). The raw data were generated by massive parallel sequencing using the shotgun approach. As expected, most of the identified DNA sequences belonged to Terrabacteria and Actinobacteria (40\% and 37\% of the total reads, respectively). The occurrence of Deinococcus-Thermus, Armatimonadetes, Chloroflexi in the epipelagic SAS waters was less anticipated. Surprising was also the detection of sequences, which are characteristic for strict anaerobes—Ignavibacteria, hydrogen-oxidizing bacteria, and archaeal methanogenic species. We suppose that the observed very broad range of phylogenetic and ecological features displayed by the SAS reads demonstrates a more intensive mixing of water masses originating from diverse ecological niches of the Aral-Syr Darya River basin than presumed before.},
  language  = {en}
}
@article{PreissLinderWendtetal.2011,
  author    = {Preiß, C. and Linder, Peter and Wendt, K. and Krystek, M. and Digel, Ilya and Gossmann, Matthias and Temiz Artmann, Ayseg{\"u}l and Porst, Dariusz and Kayser, Peter and Bassam, Rasha and Artmann, Gerhard},
  title     = {Engineering technology for plant physiology and plant stress research},
  year      = {2011},
  abstract  = {Plant physiology and plant stress: Plant physiology will be much more important for human mankind because of yield and cultivation limits of crops determined by their resistance to stress. To assess and counteract various stress factors it is necessary to conduct plant research to gain information and results on plant physiology.},
  subject      = {Pflanzenphysiologie},
  language  = {en}
}
@misc{Staat2006,
  author    = {Staat, Manfred},
  title     = {Engineering Mechanics. Lecture Notes. 2nd edition, translation of the 3rd corrected and extended German edition of "Technische Mechanik"},
  year      = {2006},
  abstract  = {English translation of the corrected lectures notes of Sebastian Kr{\"a}mer. Contents 0 Introduction to Mechanics 1 Statics of Rigid Bodies 2 Elastostatics (Strength of Materials) 3 Kinematics 4 Kinetics Literature},
  subject      = {Technische Mechanik},
  language  = {en}
}
@inproceedings{JungFrotscherStaat2018,
  author    = {Jung, Alexander and Frotscher, Ralf and Staat, Manfred},
  title     = {Electromechanical model of hiPSC-derived ventricular cardiomyocytes cocultured with fibroblasts},
  series = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK},
  booktitle = {6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK},
  pages     = {11 Seiten},
  year      = {2018},
  abstract  = {The CellDrum provides an experimental setup to study the mechanical effects of fibroblasts co-cultured with hiPSC-derived ventricular cardiomyocytes. Multi-scale computational models based on the Finite Element Method are developed. Coupled electrical cardiomyocyte-fibroblast models (cell level) are embedded into reaction-diffusion equations (tissue level) which compute the propagation of the action potential in the cardiac tissue. Electromechanical coupling is realised by an excitation-contraction model (cell level) and the active stress arising during contraction is added to the passive stress in the force balance, which determines the tissue displacement (tissue level). Tissue parameters in the model can be identified experimentally to the specific sample.},
  language  = {en}
}
@inproceedings{StaatHeitzerReindersetal.2001,
  author    = {Staat, Manfred and Heitzer, Michael and Reinders, H. and Schubert, F.},
  title     = {Einspielen und Ratchetting bei Zug- und Torsionsbelastung: Analyse und Experimente},
  year      = {2001},
  abstract  = {Traglast- und Einspielanalysen sind vereinfachte doch exakte Verfahren der klassischen Plastizit{\"a}tstheorie, die neben ausreichender Verformbarkeit keine einschr{\"a}nkenden Voraussetzungen beinhalten. Die Vereinfachungen betreffen die Beschaffung der Daten und Modelle f{\"u}r Details der Lastgeschichte und des Stoffverhaltens. Eine FEM-basierte Traglast- und Einspielanalyse f{\"u}r ideal plastisches Material wurde auf ein kinematisch verfestigendes Materialgesetz erweitert und in das Finite Element Programm PERMAS implementiert. In einem einfachen Zug-Torsionsexperiment wurde eine Hohlprobe mit konstanter Torsion und zyklischer Zugbelastung beansprucht, um die neue Implementierung zu verifizieren. Es konnte gezeigt werden, dass die Einspielanalyse gut mit den experimentellen Ergebnissen {\"u}bereinstimmt. Bei Verfestigung lassen sich wesentlich gr{\"o}ßere Sicherheiten nachweisen. Dieses Potential bedarf weiterer experimenteller Absicherung. Parallel dazu ist die Eisnpieltheorie auf fortschrittliche Verfestigungsans{\"a}tze zu erweitern.},
  subject      = {Zug-Druck-Beanspruchung},
  language  = {de}
}
@inproceedings{DigelTemizArtmannNojimaetal.2003,
  author    = {Digel, Ilya and Temiz Artmann, Ayseg{\"u}l and Nojima, H. and Artmann, Gerhard},
  title     = {Effects of plasma generated ions on bacteria : [poster]},
  year      = {2003},
  abstract  = {Summary and Conclusions PCIs were clearly effective in terms of their antibacterial effects with the strains tested. This efficacy increased with the time the bacteries were exposed to PCIs. The bactericidal action has proved to be irreversible. PCIs were significantly less effective in shadowed areas. PCI exposure caused multiple protein damages as observed in SDS PAGE studies. There was no single but multiple molecular mechanism causing the bacterial death.},
  subject      = {Clusterion},
  language  = {en}
}
@article{OezsoyluKizildagSchoeningetal.2019,
  author    = {{\"O}zsoylu, Dua and Kizildag, Sefa and Sch{\"o}ning, Michael Josef and Wagner, Torsten},
  title     = {Effect of plasma treatment on the sensor properties of a light-addressable potentiometric sensor (LAPS)},
  series = {physica status solidi a : applications and materials sciences},
  volume    = {216},
  journal   = {physica status solidi a : applications and materials sciences},
  number    = {20},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201900259},
  pages     = {8 Seiten},
  year      = {2019},
  abstract  = {A light-addressable potentiometric sensor (LAPS) is a field-effect-based (bio-) chemical sensor, in which a desired sensing area on the sensor surface can be defined by illumination. Light addressability can be used to visualize the concentration and spatial distribution of the target molecules, e.g., H+ ions. This unique feature has great potential for the label-free imaging of the metabolic activity of living organisms. The cultivation of those organisms needs specially tailored surface properties of the sensor. O2 plasma treatment is an attractive and promising tool for rapid surface engineering. However, the potential impacts of the technique are carefully investigated for the sensors that suffer from plasma-induced damage. Herein, a LAPS with a Ta2O5 pH-sensitive surface is successfully patterned by plasma treatment, and its effects are investigated by contact angle and scanning LAPS measurements. The plasma duration of 30 s (30 W) is found to be the threshold value, where excessive wettability begins. Furthermore, this treatment approach causes moderate plasma-induced damage, which can be reduced by thermal annealing (10 min at 300 °C). These findings provide a useful guideline to support future studies, where the LAPS surface is desired to be more hydrophilic by O2 plasma treatment.},
  language  = {en}
}