@article{WertIkenSchoeningetal.2021,
  author    = {Wert, Stefan and Iken, Heiko and Sch{\"o}ning, Michael Josef and Matysik, Frank-Michael},
  title     = {Development of a temperature-pulse enhanced electrochemical glucose biosensor and characterization of its stability via scanning electrochemical microscopy},
  series = {Electroanalysis},
  journal   = {Electroanalysis},
  number    = {Early View},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-4109},
  doi       = {10.1002/elan.202100089},
  year      = {2021},
  abstract  = {Glucose oxidase (GOx) is an enzyme frequently used in glucose biosensors. As increased temperatures can enhance the performance of electrochemical sensors, we investigated the impact of temperature pulses on GOx that was drop-coated on flattened Pt microwires. The wires were heated by an alternating current. The sensitivity towards glucose and the temperature stability of GOx was investigated by amperometry. An up to 22-fold increase of sensitivity was observed. Spatially resolved enzyme activity changes were investigated via scanning electrochemical microscopy. The application of short (<100 ms) heat pulses was associated with less thermal inactivation of the immobilized GOx than long-term heating.},
  language  = {en}
}
@article{WeemstraEilmannSassKlaassenetal.2013,
  author    = {Weemstra, Monique and Eilmann, Britta and Sass-Klaassen, Ute G. W. and Sterck, Frank J.},
  title     = {Summer droughts limit tree growth across 10 temperate species on a productive forest site},
  series = {Forest Ecology and Management},
  volume    = {2013},
  journal   = {Forest Ecology and Management},
  number    = {306},
  publisher = {Elsevier},
  address   = {Amsterdam},
  issn      = {0378-1127 (Print)},
  doi       = {doi:10.1016/j.foreco.2013.06.007},
  pages     = {142 -- 149},
  year      = {2013},
  language  = {en}
}
@article{WeckesserHufnagelZiemonsetal.1997,
  author    = {Weckesser, Matthias and Hufnagel, Andreas and Ziemons, Karl and Grießmeier, Martin and Sonnenberg, Frank and Hackl{\"a}nder, Thomas and Langen, Karl-J. and Holschbach, Markus and Elger, Christian E. and M{\"u}ller-G{\"a}rtner, Hans-W.},
  title     = {Effect of partial volume correction on muscarinic cholinergic receptor imaging with single-photon emission tomography in patients with temporal lobe epilepsy},
  series = {European Journal of Nuclear Medicine},
  volume    = {24},
  journal   = {European Journal of Nuclear Medicine},
  number    = {9},
  isbn      = {1619-7089},
  pages     = {1156 -- 1161},
  year      = {1997},
  abstract  = {Animal experiments and preliminary results in humans have indicated alterations of hippocampal muscarinic acetylcholine receptors (mAChR) in temporal lobe epilepsy. Patients with temporal lobe epilepsy often present with a reduction in hippocampal volume. The aim of this study was to investigate the influence of hippocampal atrophy on the quantification of mAChR with single photon emission tomography (SPET) in patients with temporal lobe epilepsy. Cerebral uptake of the muscarinic cholinergic antagonist [123I]4-iododexetimide (IDex) was investigated by SPET in patients suffering from temporal lobe epilepsy of unilateral (n=6) or predominantly unilateral (n=1) onset. Regions of interest were drawn on co-registered magnetic resonance images. Hippocampal volume was determined in these regions and was used to correct the SPET results for partial volume effects. A ratio of hippocampal IDex binding on the affected side to that on the unaffected side was used to detect changes in muscarinic cholinergic receptor density. Before partial volume correction a decrease in hippocampal IDex binding on the focus side was found in each patient. After partial volume no convincing differences remained. Our results indicate that the reduction in hippocampal IDex binding in patients with epilepsy is due to a decrease in hippocampal volume rather than to a decrease in receptor concentration.},
  language  = {en}
}
@article{WeckesserGriessmeierSchmidtetal.1998,
  author    = {Weckesser, Martin and Grießmeier, Martin and Schmidt, Daniela and Sonnenberg, Frank and Ziemons, Karl and Kemna, Lars and Holschbach, Marcus and Langen, Karl-J. and M{\"u}ller-G{\"a}rtner, Hans-W.},
  title     = {Iodine-123 α-methyl tyrosine single-photon emission tomography of cerebral gliomas: standardised evaluation of tumour uptake and extent},
  series = {European Journal of Nuclear Medicine},
  volume    = {25},
  journal   = {European Journal of Nuclear Medicine},
  number    = {2},
  isbn      = {1619-7089},
  pages     = {150 -- 156},
  year      = {1998},
  abstract  = {Single-photon emission tomography (SPET) with the amino acid analogue l-3-[123I]iodo-α-methyl tyrosine (IMT) is helpful in the diagnosis and monitoring of cerebral gliomas. Radiolabelled amino acids seem to reflect tumour infiltration more specifically than conventional methods like magnetic resonance imaging and computed tomography. Automatic tumour delineation based on maximal tumour uptake may cause an overestimation of mean tumour uptake and an underestimation of tumour extension in tumours with circumscribed peaks. The aim of this study was to develop a program for tumour delineation and calculation of mean tumour uptake which takes into account the mean background activity and is thus optimised to the problem of tumour definition in IMT SPET. Using the frequency distribution of pixel intensities of the tomograms a program was developed which automatically detects a reference brain region and draws an isocontour region around the tumour taking into account mean brain radioactivity. Tumour area and tumour/brain ratios were calculated. A three-compartment phantom was simulated to test the program. The program was applied to IMT SPET studies of 20 patients with cerebral gliomas and was compared to the results of manual analysis by three different investigators. Activity ratios and chamber extension of the phantom were correctly calculated by the automatic analysis. A method based on image maxima alone failed to determine chamber extension correctly. Manual region of interest analysis in patient studies resulted in a mean inter-observer standard deviation of 8.7\%±6.1\% (range 2.7\%-25.0\%). The mean value of the results of the manual analysis showed a significant correlation to the results of the automatic analysis (r = 0.91, P<0.0001 for the uptake ratio; r = 0.87, P<0.0001 for the tumour area). We conclude that the algorithm proposed simplifies the calculation of uptake ratios and may be used for observer-independent evaluation of IMT SPET studies. Three-dimensional tumour recognition and transfer to co-registered morphological images based on this program may be useful for the planning of surgical and radiation treatment.},
  language  = {en}
}
@article{ThielemannStaudtKriegesmann1995,
  author    = {Thielemann, Frank and Staudt, Erich and Kriegesmann, Bernd},
  title     = {Kooperation als Erfolgsfak­tor ostdeutscher Unternehmen. Ergebnisse einer empirischen Untersu­chung zur Ko­operationslandschaft in Ost­deutschland. Staudt, E.; Kriegesmann, B.; Thielemann, F.},
  series = {Zeitschrift f{\"u}r Betriebswirtschaft ZfB. 65 (1995), H. 11},
  journal   = {Zeitschrift f{\"u}r Betriebswirtschaft ZfB. 65 (1995), H. 11},
  isbn      = {0044-2372},
  pages     = {1209 -- 1230},
  year      = {1995},
  language  = {de}
}
@article{ThielemannStaudtKriegesmann1997,
  author    = {Thielemann, Frank and Staudt, Erich and Kriegesmann, Bernd},
  title     = {Neuformierung von Wertsch{\"o}pfungsketten: Das Beispiel Druckindustrie . Staudt, Erich; Kriegesmann, Bernd; Thielemann, Frank},
  series = {Zeitschrift F{\"u}hrung und Organisation. 96 (1997), H. 2},
  journal   = {Zeitschrift F{\"u}hrung und Organisation. 96 (1997), H. 2},
  isbn      = {0044-3212},
  pages     = {75 -- 80},
  year      = {1997},
  language  = {de}
}
@article{ThielemannStaudtKriegesmann1998,
  author    = {Thielemann, Frank and Staudt, Erich and Kriegesmann, Bernd},
  title     = {Kooperationsverhalten in der Druckindustrie - zwischen Bestandssicherung und Offensive. Staudt, Erich; Kriegesmann, Bernd; Thielemann, Frank},
  series = {Die Betriebswirtschaft. 58 (1998), H. 6},
  journal   = {Die Betriebswirtschaft. 58 (1998), H. 6},
  isbn      = {0342-7064},
  pages     = {803 -- 815},
  year      = {1998},
  language  = {de}
}
@article{ThielemannStaudt1997,
  author    = {Thielemann, Frank and Staudt, Erich},
  title     = {Kompetenz zur Innovation: Vom Druckbetrieb zum Multimedia-Dienstleister . Staudt, E.; Thielemann, F.},
  series = {News Letter (der Gesellschaft f{\"u}r Wirtschaftsf{\"o}rde­rung Duisburg) (1997)},
  journal   = {News Letter (der Gesellschaft f{\"u}r Wirtschaftsf{\"o}rde­rung Duisburg) (1997)},
  pages     = {3 -- 3},
  year      = {1997},
  language  = {de}
}
@article{ThielemannStaudt1997,
  author    = {Thielemann, Frank and Staudt, Erich},
  title     = {Reicht die Kompetenz zur Innovation? Staudt, E.; Thielemann, F.},
  series = {OP DruckMagazin. 39 (1997), H. 10},
  journal   = {OP DruckMagazin. 39 (1997), H. 10},
  isbn      = {0030-0594},
  pages     = {30 -- 32},
  year      = {1997},
  language  = {de}
}
@article{ThielemannSchaffner1993,
  author    = {Thielemann, Frank and Schaffner, M.},
  title     = {Innovationswiderst{\"a}nde bei der Einf{\"u}hrung neuer Tech­nologien. Schaffner, M.; Thielemann, F.},
  series = {Deutscher Drucker. 1992/93 (1993), H. 42},
  journal   = {Deutscher Drucker. 1992/93 (1993), H. 42},
  isbn      = {0012-1096},
  pages     = {g15 -- ff},
  year      = {1993},
  language  = {de}
}