@article{WeckesserGriessmeierSchmidtetal.1998, author = {Weckesser, Martin and Grießmeier, Martin and Schmidt, Daniela and Sonnenberg, Frank and Ziemons, Karl and Kemna, Lars and Holschbach, Marcus and Langen, Karl-J. and M{\"u}ller-G{\"a}rtner, Hans-W.}, title = {Iodine-123 α-methyl tyrosine single-photon emission tomography of cerebral gliomas: standardised evaluation of tumour uptake and extent}, series = {European Journal of Nuclear Medicine}, volume = {25}, journal = {European Journal of Nuclear Medicine}, number = {2}, isbn = {1619-7089}, pages = {150 -- 156}, year = {1998}, abstract = {Single-photon emission tomography (SPET) with the amino acid analogue l-3-[123I]iodo-α-methyl tyrosine (IMT) is helpful in the diagnosis and monitoring of cerebral gliomas. Radiolabelled amino acids seem to reflect tumour infiltration more specifically than conventional methods like magnetic resonance imaging and computed tomography. Automatic tumour delineation based on maximal tumour uptake may cause an overestimation of mean tumour uptake and an underestimation of tumour extension in tumours with circumscribed peaks. The aim of this study was to develop a program for tumour delineation and calculation of mean tumour uptake which takes into account the mean background activity and is thus optimised to the problem of tumour definition in IMT SPET. Using the frequency distribution of pixel intensities of the tomograms a program was developed which automatically detects a reference brain region and draws an isocontour region around the tumour taking into account mean brain radioactivity. Tumour area and tumour/brain ratios were calculated. A three-compartment phantom was simulated to test the program. The program was applied to IMT SPET studies of 20 patients with cerebral gliomas and was compared to the results of manual analysis by three different investigators. Activity ratios and chamber extension of the phantom were correctly calculated by the automatic analysis. A method based on image maxima alone failed to determine chamber extension correctly. Manual region of interest analysis in patient studies resulted in a mean inter-observer standard deviation of 8.7\%±6.1\% (range 2.7\%-25.0\%). The mean value of the results of the manual analysis showed a significant correlation to the results of the automatic analysis (r = 0.91, P<0.0001 for the uptake ratio; r = 0.87, P<0.0001 for the tumour area). We conclude that the algorithm proposed simplifies the calculation of uptake ratios and may be used for observer-independent evaluation of IMT SPET studies. Three-dimensional tumour recognition and transfer to co-registered morphological images based on this program may be useful for the planning of surgical and radiation treatment.}, language = {en} } @article{ThielemannStaudtKriegesmann1998, author = {Thielemann, Frank and Staudt, Erich and Kriegesmann, Bernd}, title = {Kooperationsverhalten in der Druckindustrie - zwischen Bestandssicherung und Offensive. Staudt, Erich; Kriegesmann, Bernd; Thielemann, Frank}, series = {Die Betriebswirtschaft. 58 (1998), H. 6}, journal = {Die Betriebswirtschaft. 58 (1998), H. 6}, isbn = {0342-7064}, pages = {803 -- 815}, year = {1998}, language = {de} } @book{ThielemannStaudt1998, author = {Thielemann, Frank and Staudt, Erich}, title = {Innovation durch strategische Allianzen : ein Wegweiser f{\"u}r die Druck- und Medienbranche . Staudt, Erich; Thielemann, Frank}, publisher = {IAI, Inst. f{\"u}r Angewandte Innovationsforschung}, address = {Bochum}, isbn = {3-928854-14-3}, pages = {96 Bl.: graph. Darst.}, year = {1998}, language = {de} } @article{Thielemann1998, author = {Thielemann, Frank}, title = {Mit strategischen Allianzen ins n{\"a}chste Jahrtausend}, series = {Druckspiegel. 53 (1998), H. 5}, journal = {Druckspiegel. 53 (1998), H. 5}, isbn = {0012-6500}, pages = {21 -- 24}, year = {1998}, language = {de} } @article{Thielemann1998, author = {Thielemann, Frank}, title = {Druckindustrielle Innovation}, series = {Der Siebdruck. 47 (1998), H. 4}, journal = {Der Siebdruck. 47 (1998), H. 4}, isbn = {0178-2835}, pages = {32 -- ff}, year = {1998}, language = {de} } @article{Thielemann1998, author = {Thielemann, Frank}, title = {Mit vereinten Kr{\"a}ften}, series = {Trockenbau, Akustik : Magazin f{\"u}r Planung und Ausf{\"u}hrung. 15 (1998), H. 5}, journal = {Trockenbau, Akustik : Magazin f{\"u}r Planung und Ausf{\"u}hrung. 15 (1998), H. 5}, isbn = {0179-8006}, pages = {60 -- 68}, year = {1998}, language = {de} } @inproceedings{SpaeteWollscheidMeliss1998, author = {Sp{\"a}te, Frank and Wollscheid, Georg and Meliß, Michael}, title = {Erdreichw{\"a}rmetauscher im Solar-Campus J{\"u}lich}, series = {Deutschlands Weg in eine solare Zukunft : Tagungsband; 26. - 30. Juni 1998 Fachhochschule K{\"o}ln / 11. Internationales Sonnenforum}, booktitle = {Deutschlands Weg in eine solare Zukunft : Tagungsband; 26. - 30. Juni 1998 Fachhochschule K{\"o}ln / 11. Internationales Sonnenforum}, publisher = {Solar Promotion}, address = {M{\"u}nchen}, organization = {Deutsche Gesellschaft f{\"u}r Sonnenenergie}, pages = {591 -- 598}, year = {1998}, language = {de} } @inproceedings{SpaeteHubrichKeipetal.1998, author = {Sp{\"a}te, Frank and Hubrich, J{\"o}rg and Keip, Wolfgang and Meliß, Michael}, title = {Der Solar-Campus J{\"u}lich - Stand der Arbeiten}, series = {Deutschlands Weg in eine solare Zukunft : Tagungsband; 26. - 30. Juni 1998 Fachhochschule K{\"o}ln / 11. Internationales Sonnenforum}, booktitle = {Deutschlands Weg in eine solare Zukunft : Tagungsband; 26. - 30. Juni 1998 Fachhochschule K{\"o}ln / 11. Internationales Sonnenforum}, publisher = {Solar Promotion}, address = {M{\"u}nchen}, organization = {Deutsche Gesellschaft f{\"u}r Sonnenenergie}, pages = {666 -- 672}, year = {1998}, language = {de} } @inproceedings{RepschlaegerHafnerMelissetal.1998, author = {Repschl{\"a}ger, Horst and Hafner, Bernd and Meliß, Michael and Philippi, Helga and Sp{\"a}te, Frank}, title = {Vergleich verschiedener Netzvarianten am Beispiel des geplanten solaren Nahw{\"a}rmesystems f{\"u}r den Solar-Campus J{\"u}lich}, series = {8. Symposium Thermische Solarenergie : Ort: Bildungszentrum der Hanns-Seidel-Stiftung, Kloster Banz, Staffelstein. Termin: 13. - 15. Mai 1998 / OTTI, Technologie-Kolleg}, booktitle = {8. Symposium Thermische Solarenergie : Ort: Bildungszentrum der Hanns-Seidel-Stiftung, Kloster Banz, Staffelstein. Termin: 13. - 15. Mai 1998 / OTTI, Technologie-Kolleg}, publisher = {OTTI}, address = {Regensburg}, pages = {310 -- 314}, year = {1998}, language = {de} } @inproceedings{RazenSpaeteMelissetal.1998, author = {Razen, Manfred and Sp{\"a}te, Frank and Meliß, Michael and Breuer, Maria and Hubrich, J{\"o}rg and Rischert, Christa}, title = {Aus-, Fort- und Weiterbildung am Solar-Institut J{\"u}lich}, series = {Deutschlands Weg in eine solare Zukunft : Tagungsband; 26. - 30. Juni 1998 Fachhochschule K{\"o}ln / 11. Internationales Sonnenforum}, booktitle = {Deutschlands Weg in eine solare Zukunft : Tagungsband; 26. - 30. Juni 1998 Fachhochschule K{\"o}ln / 11. Internationales Sonnenforum}, publisher = {Solar Promotion}, address = {M{\"u}nchen}, organization = {Deutsche Gesellschaft f{\"u}r Sonnenenergie}, pages = {1071 -- 1078}, year = {1998}, language = {de} } @inproceedings{KrugRazenSpaeteetal.1998, author = {Krug, Wolfgang and Razen, Manfred and Sp{\"a}te, Frank and Meliß, Michael}, title = {Solarpraktikum f{\"u}r Ferieng{\"a}ste}, series = {Deutschlands Weg in eine solare Zukunft : Tagungsband; 26. - 30. Juni 1998 Fachhochschule K{\"o}ln / 11. Internationales Sonnenforum}, booktitle = {Deutschlands Weg in eine solare Zukunft : Tagungsband; 26. - 30. Juni 1998 Fachhochschule K{\"o}ln / 11. Internationales Sonnenforum}, publisher = {Solar Promotion}, address = {M{\"u}nchen}, organization = {Deutsche Gesellschaft f{\"u}r Sonnenenergie}, pages = {1102 -- 1109}, year = {1998}, language = {de} }