@article{ZiemonsKleinesErkenetal.1997, author = {Ziemons, Karl and Kleines, H. and Erken, I. and Knoben, J. and Zwoll, K.}, title = {IME-DV Projekt: M-FIRBe, Multi-Modality Functional Imaging for Brain Research}, series = {Bildverarbeitung f{\"u}r die Medizin : Algorithmen - Systeme - Anwendungen}, journal = {Bildverarbeitung f{\"u}r die Medizin : Algorithmen - Systeme - Anwendungen}, editor = {Lehmann, Thomas}, publisher = {Verl. der. Augustinus-Buchh.}, address = {Aachen}, isbn = {3-86073-519-5}, pages = {363 -- 366}, year = {1997}, language = {de} } @article{ZiemonsHerzogFeinendegen1990, author = {Ziemons, Karl and Herzog, H. and Feinendegen, L. E.}, title = {Iterative image reconstruction with weighted pixel contribution to projection element}, series = {European Journal of Nuclear Medicine}, volume = {16}, journal = {European Journal of Nuclear Medicine}, number = {7}, isbn = {1619-7089}, pages = {403 -- 403}, year = {1990}, language = {en} } @article{ZiemonsHerzogBosettietal.1992, author = {Ziemons, Karl and Herzog, H. and Bosetti, P. and Feinendegen, L. E.}, title = {Iterative image reconstruction with weighted pixel contribution to projection elements}, series = {European Journal of Nuclear Medicine}, volume = {19}, journal = {European Journal of Nuclear Medicine}, number = {8}, isbn = {1619-7089}, pages = {588 -- 588}, year = {1992}, language = {en} } @article{ZiemonsHeinrichsStreunetal.2004, author = {Ziemons, Karl and Heinrichs, U. and Streun, M. and Pietrzyk, U.}, title = {Validation of GEANT3 simulation studies with a dual-head PMT ClearPET™ prototype}, series = {2003 IEEE Nuclear Science Symposium Conference Record, Vol. 5}, journal = {2003 IEEE Nuclear Science Symposium Conference Record, Vol. 5}, issn = {1082-3654}, pages = {3053 -- 3056}, year = {2004}, abstract = {The ClearPET™ project is proposed by working groups of the Crystal Clear Collaboration (CCC) to develop a 2nd generation high performance small animal positron emission tomograph (PET). High sensitivity and high spatial resolution is foreseen for the ClearPET™ camera by using a phoswich arrangement combining mixed lutetium yttrium aluminum perovskite (LuYAP:Ce) and lutetium oxyorthosilicate (LSO) scintillating crystals. Design optimizations for the first photomultiplier tube (PMT) based ClearPET camera are done with a Monte-Carlo simulation package implemented on GEANT3 (CERN, Geneva, Switzerland). A dual-head prototype has been built to test the frontend electronics and was used to validate the implementation of the GEANT3 simulation tool. Multiple simulations were performed following the experimental protocols to measure the intrinsic resolution and the sensitivity profile in axial and radial direction. Including a mean energy resolution of about 27.0\% the simulated intrinsic resolution is about (1.41±0.11)mm compared to the measured of (1.48±0.06)mm. The simulated sensitivity profiles show a mean square deviation of 12.6\% in axial direction and 3.6\% in radial direction. Satisfactorily these results are representative for all designs and confirm the scanner geometry.}, language = {en} } @article{ZiemonsBruyndonckxPerezetal.2008, author = {Ziemons, Karl and Bruyndonckx, P. and Perez, J. M. and Pietrzyk, U. and Rato, P. and Tavernier, S.}, title = {Beyond ClearPET: Next Aims}, series = {5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro Symposium Proceedings ISBI 2008}, journal = {5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro Symposium Proceedings ISBI 2008}, isbn = {978-1-4244-2003-2}, pages = {1421 -- 1424}, year = {2008}, abstract = {The CRYSTAL CLEAR collaboration, in short CCC, is a consortium of 12 academic institutions, mainly from Europe, joining efforts in the area of developing instrumentation for nuclear medicine and medical imaging. In the framework of the CCC a high performance small animal PET system, called ClearPET, was developed by using new technologies in electronics and crystals in a phoswich arrangement combining two types of lutetium- based scintillator materials: LSO:Ce and LuYAP:Ce. Our next aim will be the development of hybrid image systems. Hybrid MR-PET imaging has many unique advantages for brain research. This has sparked a new research line within CCC for the development of novel MR-PET compatible technologies. MRI is not as sensitive as PET but PET has poorer spatial resolution than MRI. Two major advantages of PET are sensitivity and its ability to acquire metabolic information. To assess these innovations, the development of a 9.4T hybrid animal MR-PET scanner is proposed based on an existing 9.4T MR scanner that will be adapted to enable simultaneous acquisition of MR and PET data using cutting- edge technology for both MR and PET.}, language = {en} } @article{ZiemonsBerghoffLanskeetal.1988, author = {Ziemons, Karl and Berghoff, G. and Lanske, D. and Schultze, K.}, title = {Strangeness production in deep inelastic muon-nucleon scattering}, series = {Verhandlungen der Deutschen Physikalischen Gesellschaft}, volume = {23}, journal = {Verhandlungen der Deutschen Physikalischen Gesellschaft}, number = {5}, isbn = {0420-0195}, pages = {T309 -- T309}, year = {1988}, language = {en} } @article{ZiemonsAuffrayBarbieretal.2005, author = {Ziemons, Karl and Auffray, E. and Barbier, R. and Brandenburg, G. and Bruyndonckx, P.}, title = {The ClearPET™ project: Development of a 2nd generation high-performance small animal PET scanner}, series = {Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, volume = {537}, journal = {Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, number = {1-2}, issn = {0168-9002}, pages = {307 -- 311}, year = {2005}, abstract = {Second generation high-performance PET scanners, called ClearPET™1, have been developed by working groups of the Crystal Clear Collaboration (CCC). High sensitivity and high spatial resolution for the ClearPET camera is achieved by using a phoswich arrangement combining two different types of lutetium-based scintillator materials: LSO from CTI and LuYAP:Ce from the CCC (ISTC project). In a first ClearPET prototype, phoswich arrangements of 8×8 crystals of 2×2×10 mm3 are coupled to multi-channel photomultiplier tubes (Hamamatsu R7600). A unit of four PMTs arranged in-line represents one of 20 sectors of the ring design. The opening diameter of the ring is 120 mm, the axial detector length is 110 mm.The PMT pulses are digitized by free-running ADCs and digital data processing determines the gamma energy, the phoswich layer and even the exact pulse starting time, which is subsequently used for coincidence detection. The gantry allows rotation of the detector modules around the field of view. Preliminary data shows a correct identification of the crystal layer about (98±1)\%. Typically the energy resolution is (23.3±0.5)\% for the luyap layer and (15.4±0.4)\% for the lso layer. early studies showed the timing resolution of 2 ns FWHM and 4.8 ns FWTM. the intrinsic spatial resolution ranges from 1.37 mm to 1.61 mm full-width of half-maximum (FWHM) with a mean of 1.48 mm FWHM. further improvements in image and energy resolution are expected when the system geometry is fully modeled.}, language = {en} } @article{ZiemonsAuffrayBarbieretal.2004, author = {Ziemons, Karl and Auffray, E. and Barbier, R. and Brandenburg, G.}, title = {The ClearPET TM LSO/LuYAP phoswich scanner: a high performance small animal PET system}, series = {2003 IEEE Nuclear Science Symposium Conference Record, Vol. 3}, journal = {2003 IEEE Nuclear Science Symposium Conference Record, Vol. 3}, issn = {1082-3654}, pages = {1728 -- 1732}, year = {2004}, abstract = {A 2nd generation high performance small animal PET scanner, called ClearPET™, has been designed and a first prototype is built by working groups of the Crystal Clear Collaboration (CCC). In order to achieve high sensitivity and maintain good uniform spatial resolution over the field of view in high resolution PET systems, it is necessary to extract the depth of interaction (DOI) information and correct for spatial degradation. The design of the first ClearPET™ Demonstrator based on the use of the multi-anode photomultiplier tube (Hamamatsu R7600-M64) and a LSO/LuYAP phoswich matrix. The two crystal layers of 8*8 crystals (2*2*10 mm3) are stacked on each other and mounted without light guide as one to one on the PMT. A unit of four PMTs arranged in-line represents one of 20 sectors of the ring design. The opening diameter of the crystal ring is 137 mm, the axial detector length is 110 mm. The PMT pulses are digitized by free-running ADCs and digital data processing determines the gamma energy, the phoswich layer and even the pulse arrival time. Single gamma interactions are recorded and coincidences are found by software. The gantry allows rotation of the detector modules around the field of view. The measurements have been done using the first LSO/LuYAP detector cassettes.}, language = {en} } @article{ZiemonsAchtenAuffrayetal.2004, author = {Ziemons, Karl and Achten, R. and Auffray, E. and M{\"u}ller-Veggian, Mattea}, title = {The ClearPET™ neuro scanner: a dedicated LSO/LuYAP phoswich small animal PET scanner}, series = {2004 IEEE Nuclear Science Symposium conference record : Nuclear Science Symposium, Medical Imaging Conference ; 16 - 22 October 2004, Rome, Italy ; [including the Symposium on Nuclear Power System (SNPS), 14th Room Temperature Semiconductor X- and Gamma-Ray Detectors Workshop and special focus workshops] / NPSS, Nuclear \& Plasma Sciences Society. Guest ed.: J. Anthony Seibert}, journal = {2004 IEEE Nuclear Science Symposium conference record : Nuclear Science Symposium, Medical Imaging Conference ; 16 - 22 October 2004, Rome, Italy ; [including the Symposium on Nuclear Power System (SNPS), 14th Room Temperature Semiconductor X- and Gamma-Ray Detectors Workshop and special focus workshops] / NPSS, Nuclear \& Plasma Sciences Society. Guest ed.: J. Anthony Seibert}, publisher = {IEEE Operations Center}, address = {Piscataway, NJ}, issn = {1082-3654}, pages = {2430 -- 2433}, year = {2004}, language = {en} } @article{Ziemons1987, author = {Ziemons, Karl}, title = {Jet production and fragmentation properties in deep inelastic muon scattering}, series = {Zeitschrift f{\"u}r Physik C : Particles and Fields}, volume = {36}, journal = {Zeitschrift f{\"u}r Physik C : Particles and Fields}, number = {4}, isbn = {0170-9739}, pages = {527 -- 543}, year = {1987}, language = {en} }