@article{LinderDigelTemizArtmannetal.2007,
  author    = {Linder, Peter and Digel, Ilya and Temiz Artmann, Ayseg{\"u}l and Kayser, Peter and Porst, Dariusz and Artmann, Gerhard},
  title     = {High-throughput testing of mechanical forces generated in thin cell and tissue layers},
  series = {Tissue Engineering. 13 (2007), H. 7},
  journal   = {Tissue Engineering. 13 (2007), H. 7},
  isbn      = {1076-3279},
  pages     = {1778 -- 1778},
  year      = {2007},
  language  = {en}
}
@article{UysalFiratCreutzetal.2022,
  author    = {Uysal, Karya and Firat, Ipek Serat and Creutz, Till and Aydin, Inci Cansu and Artmann, Gerhard and Teusch, Nicole and Temiz Artmann, Ayseg{\"u}l},
  title     = {A novel in vitro wound healing assay using free-standing, ultra-thin PDMS membranes},
  series = {membranes},
  volume    = {2023},
  journal   = {membranes},
  number    = {13(1)},
  publisher = {MDPI},
  address   = {Basel},
  doi       = {10.3390/membranes13010022},
  pages     = {Artikel 22},
  year      = {2022},
  abstract  = {Advances in polymer science have significantly increased polymer applications in life sciences. We report the use of free-standing, ultra-thin polydimethylsiloxane (PDMS) membranes, called CellDrum, as cell culture substrates for an in vitro wound model. Dermal fibroblast monolayers from 28- and 88-year-old donors were cultured on CellDrums. By using stainless steel balls, circular cell-free areas were created in the cell layer (wounding). Sinusoidal strain of 1 Hz, 5\% strain, was applied to membranes for 30 min in 4 sessions. The gap circumference and closure rate of un-stretched samples (controls) and stretched samples were monitored over 4 days to investigate the effects of donor age and mechanical strain on wound closure. A significant decrease in gap circumference and an increase in gap closure rate were observed in trained samples from younger donors and control samples from older donors. In contrast, a significant decrease in gap closure rate and an increase in wound circumference were observed in the trained samples from older donors. Through these results, we propose the model of a cell monolayer on stretchable CellDrums as a practical tool for wound healing research. The combination of biomechanical cell loading in conjunction with analyses such as gene/protein expression seems promising beyond the scope published here.},
  language  = {en}
}
@inproceedings{BayerHeschelerArtmannetal.2019,
  author    = {Bayer, Robin and Hescheler, J{\"u}rgen and Artmann, Gerhard and Temiz Artmann, Ayseg{\"u}l},
  title     = {Treating arterial hypertension in a cell culture well},
  series = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH AachenW},
  booktitle = {3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH AachenW},
  editor    = {Staat, Manfred and Erni, Daniel},
  publisher = {Universit{\"a}t Duisburg-Essen},
  address   = {Duisburg},
  organization    = {MedTech Symposium},
  isbn      = {978-3-940402-22-6},
  doi       = {10.17185/duepublico/48750},
  pages     = {5 -- 6},
  year      = {2019},
  abstract  = {Hypertension describes the pathological increase of blood pressure, which is most commonly associated with the increase of vascular wall stiffness [1]. Referring to the "Deutsche Bluthochdruck Liga" this pathology shows a growing trend in our aging society. In order to find novel pharmacological and probably personalized treatments, we want to present a functional approach to study biomechanical properties of a human aortic vascular model. In this method review we will give an overview of recent studies which were carried out with the CellDrum technology [2] and underline the added value to already existing standard procedures known from the field of physiology. Herein described CellDrum technology is a system to measure functional mechanical properties of cell monolayers and thin tissue constructs in-vitro. Additionally, the CellDrum enables to elucidate the mechanical response of cells to pharmacological drugs, toxins and vasoactive agents. Due to its highly flexible polymer support, cells can also be mechanically stimulated by steady and cyclic biaxial stretching.},
  language  = {en}
}
@article{GossmannFrotscherLinderetal.2016,
  author    = {Goßmann, Matthias and Frotscher, Ralf and Linder, Peter and Bayer, Robin and Epple, U. and Staat, Manfred and Temiz Artmann, Ayseg{\"u}l and Artmann, Gerhard},
  title     = {Mechano-pharmacological characterization of cardiomyocytes derived from human induced pluripotent stem cells},
  series = {Cellular physiology and biochemistry},
  volume    = {38},
  journal   = {Cellular physiology and biochemistry},
  number    = {3},
  publisher = {Karger},
  address   = {Basel},
  issn      = {1421-9778 (Online)},
  doi       = {10.1159/000443124},
  pages     = {1182 -- 1198},
  year      = {2016},
  abstract  = {Background/Aims: Common systems for the quantification of cellular contraction rely on animal-based models, complex experimental setups or indirect approaches. The herein presented CellDrum technology for testing mechanical tension of cellular monolayers and thin tissue constructs has the potential to scale-up mechanical testing towards medium-throughput analyses. Using hiPS-Cardiac Myocytes (hiPS-CMs) it represents a new perspective of drug testing and brings us closer to personalized drug medication. Methods: In the present study, monolayers of self-beating hiPS-CMs were grown on ultra-thin circular silicone membranes and deflect under the weight of the culture medium. Rhythmic contractions of the hiPS-CMs induced variations of the membrane deflection. The recorded contraction-relaxation-cycles were analyzed with respect to their amplitudes, durations, time integrals and frequencies. Besides unstimulated force and tensile stress, we investigated the effects of agonists and antagonists acting on Ca²⁺ channels (S-Bay K8644/verapamil) and Na⁺ channels (veratridine/lidocaine). Results: The measured data and simulations for pharmacologically unstimulated contraction resembled findings in native human heart tissue, while the pharmacological dose-response curves were highly accurate and consistent with reference data. Conclusion: We conclude that the combination of the CellDrum with hiPS-CMs offers a fast, facile and precise system for pharmacological, toxicological studies and offers new preclinical basic research potential.},
  language  = {en}
}
@article{TemizArtmannKayser2008,
  author    = {Temiz Artmann, Ayseg{\"u}l and Kayser, Peter},
  title     = {Why is Sepsis an Ongoing Clinical Challenge? Lipopolysaccharide Effects on Red Blood Cell Volume / Temiz, Ayseg{\"u}l ; Kayser, Peter},
  series = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)},
  journal   = {Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)},
  publisher = {Springer},
  address   = {Berlin},
  isbn      = {978-3-540-75408-4},
  pages     = {497 -- 508},
  year      = {2008},
  language  = {en}
}
@article{TemizArtmannKayatekinUysaletal.2005,
  author    = {Temiz Artmann, Ayseg{\"u}l and Kayatekin, Muammer B. and Uysal, N. and Resmi, H.},
  title     = {Does antioxidant supplementation alter the effects of acute exercise on erythrocyte aggregation, deformability and endothelium adhesion in untrained rats? Kayatekin, Muammer B.; Uysal N.; Resmi, H.; Bediz, Seref C.; Temiz Artmann, A.; Gen{\c{c}}, S.; Tugyan, K.},
  series = {International Journal for Vitamin and Nutrition Research. 75 (2005), H. 4},
  journal   = {International Journal for Vitamin and Nutrition Research. 75 (2005), H. 4},
  isbn      = {0300-9831},
  pages     = {243 -- 250},
  year      = {2005},
  language  = {en}
}
@article{TemizArtmannResmiAkhunlaretal.2005,
  author    = {Temiz Artmann, Ayseg{\"u}l and Resmi, Halil and Akhunlar, H{\"u}lya and G{\"u}ner, G{\"u}l},
  title     = {In vitro effects of high glucose concentrations on membrane protein sulfhydryl oxidation, G-actin and deformability of human erythrocytes. Resmi, Halil ; Akhunlar, H{\"u}lya ; Temiz Artmann, Ayseg{\"u}l ; G{\"u}ner, G{\"u}l},
  series = {Cell biochemistry and function. 23 (2005), H. 3},
  journal   = {Cell biochemistry and function. 23 (2005), H. 3},
  isbn      = {0263-6484},
  pages     = {163 -- 168},
  year      = {2005},
  language  = {en}
}
@article{TemizArtmannCavdarYeniceriogluetal.2003,
  author    = {Temiz Artmann, Ayseg{\"u}l and Cavdar, C. and Yenicerioglu, Y. and Caliskan, S.},
  title     = {The effects of intravenous iron treatment on oxidant stress and erythrocyte deformability in haemodialysis patients. Cavdar, C.; Temiz, A.; Yenicerioglu, Y.; Caliskan, S.; Celik, A.; Sifil, A.; Onvural, B.; Camsari, T.},
  series = {Scandinavian Journal of Urology and Nephrology. 37 (2003), H. 1},
  journal   = {Scandinavian Journal of Urology and Nephrology. 37 (2003), H. 1},
  isbn      = {0036-5599},
  pages     = {77 -- 82},
  year      = {2003},
  language  = {en}
}
@article{TemizArtmannYalcinResmietal.2002,
  author    = {Temiz Artmann, Ayseg{\"u}l and Yalcin, Ozlem and Resmi, Halil and Baskurt, Oguz K.},
  title     = {Can white blood cell activation be one of the major factors that affect hemorheological parameters during and after exercise?},
  series = {Clinical Hemorheology and Microcirculation. 26 (2002), H. 3},
  journal   = {Clinical Hemorheology and Microcirculation. 26 (2002), H. 3},
  isbn      = {1386-0291},
  pages     = {189 -- 193},
  year      = {2002},
  language  = {en}
}
@article{TemizArtmannBaskurtPekcetinetal.2000,
  author    = {Temiz Artmann, Ayseg{\"u}l and Baskurt, Oguz K. and Pekcetin, C. and Kandemir, F.},
  title     = {Leukocyte activation, oxidant stress and red blood cell properties after acute, exhausting exercise in rats. Temiz, A.; Baskurt, O. K., Pekcetin, C.; Kandemir, F.; G{\"u}re, A.},
  series = {Clinical Hemorheology and Microcirculation. 22 (2000), H. 4},
  journal   = {Clinical Hemorheology and Microcirculation. 22 (2000), H. 4},
  isbn      = {1386-0291},
  pages     = {253 -- 259},
  year      = {2000},
  language  = {en}
}
@article{TemizArtmannYolcuogluOnaletal.1999,
  author    = {Temiz Artmann, Ayseg{\"u}l and Yolcuoglu, B. and Onal, M. A. and Sipahi, O.},
  title     = {The effect of skin transplantation on tumour growth in mice. Yolcuoglu, B.; Onal, M. A.; Sipahi, O.; Temiz, A.; Pekcetin, C.; Acikg{\"o}z, O.; Kar, H.; G{\"u}re A.},
  series = {The American Journal of Surgery. 178 (1999), H. 4},
  journal   = {The American Journal of Surgery. 178 (1999), H. 4},
  isbn      = {0002-9610},
  pages     = {329 -- 330},
  year      = {1999},
  language  = {en}
}
@article{TemizArtmannAtesUeretmenetal.1998,
  author    = {Temiz Artmann, Ayseg{\"u}l and Ates, H. and {\"U}retmen, {\"O}. and Andac, K.},
  title     = {Erythrocyte deformability in high-tension and normal tension glaucoma. Ates, H.; {\"U}retmen, {\"O}.; Temiz, A.; Andac, K.},
  series = {International Ophthalmology. 22 (1998), H. 1},
  journal   = {International Ophthalmology. 22 (1998), H. 1},
  isbn      = {0165-5701},
  pages     = {7 -- 12},
  year      = {1998},
  language  = {en}
}
@article{TemizArtmannBaskurtMeiselman1998,
  author    = {Temiz Artmann, Ayseg{\"u}l and Baskurt, O. K. and Meiselman, H. J.},
  title     = {Effect of superoxide anions on red blood cell rheologic properties. Baskurt, O. K.; Temiz, A.; Meiselman, H. J.},
  series = {Free Radical Biology and Medicine. 24 (1998), H. 1},
  journal   = {Free Radical Biology and Medicine. 24 (1998), H. 1},
  isbn      = {0891-5849},
  pages     = {102 -- 110},
  year      = {1998},
  language  = {en}
}
@article{TemizArtmannBaskurtMeiselman1997,
  author    = {Temiz Artmann, Ayseg{\"u}l and Baskurt, O. K. and Meiselman, H. J.},
  title     = {Red blood cell aggregation in experimental sepsis . Baskurt, O. K.; Temiz, A.; Meiselman, H. J.},
  series = {Journal of Laboratory and Clinical Medicine. 130 (1997), H. 2},
  journal   = {Journal of Laboratory and Clinical Medicine. 130 (1997), H. 2},
  isbn      = {0022-2143},
  pages     = {183 -- 190},
  year      = {1997},
  language  = {en}
}
@article{TemizArtmannBaskurtEdremitlioglu1995,
  author    = {Temiz Artmann, Ayseg{\"u}l and Baskurt, O. K. and Edremitlioglu, M.},
  title     = {Effect of erythrocyte deformability on myocardial hematocrit gradient. Baskurt, O.K.; Edremitlioglu, M.; Temiz, A.},
  series = {American Journal of Physiology: Heart and Circulatory Physiology. 268 (1995), H. 1},
  journal   = {American Journal of Physiology: Heart and Circulatory Physiology. 268 (1995), H. 1},
  isbn      = {0363-6135},
  pages     = {260 -- 264},
  year      = {1995},
  language  = {en}
}
@article{TemizArtmannBaskurtEdremitlioglu1994,
  author    = {Temiz Artmann, Ayseg{\"u}l and Baskurt, O. K. and Edremitlioglu, M.},
  title     = {In vitro effects of in vivo activated leukocytes on red blood cell filterability and lipid peroxidation. Baskurt, O.K.; Edremitlioglu, M.; Temiz, A.},
  series = {Clinical Hemorheology. 14 (1994), H. 4},
  journal   = {Clinical Hemorheology. 14 (1994), H. 4},
  pages     = {591 -- 596},
  year      = {1994},
  language  = {en}
}
@article{TemizArtmannAkhisarogluSercanetal.2005,
  author    = {Temiz Artmann, Ayseg{\"u}l and Akhisaroglu, M. and Sercan, Z. and Kayatekin, B. M.},
  title     = {Adhesion of Erythrocytes to Endothelial Cells After Acute Exercise: Differences in Red Blood Cells from Juvenile and Adult Rats. Temiz Artmann, A.; Akhisaroglu, M.; Sercan, Z.; Kayatekin, BM.; Yorukoglu, K.; Kirkali, G.},
  series = {Physiological Research (2005)},
  journal   = {Physiological Research (2005)},
  isbn      = {0862-8408},
  year      = {2005},
  language  = {en}
}
@article{ErbayraktarYilmazTemizArtmannetal.2007,
  author    = {Erbayraktar, Zubeyde and Yilmaz, Osman and Temiz Artmann, Ayseg{\"u}l and Cehreli, Ruksan and Coker, Canan},
  title     = {Effects of Selenium Supplementation on Antioxidant Defense and Glucose Homeostasis in Experimental Diabetes Mellitus},
  series = {Biological Trace Element Research},
  volume    = {118},
  journal   = {Biological Trace Element Research},
  number    = {3},
  issn      = {1559-0720},
  pages     = {217 -- 226},
  year      = {2007},
  language  = {en}
}
@article{TemizArtmannSaklamazComlekcietal.2005,
  author    = {Temiz Artmann, Ayseg{\"u}l and Saklamaz, Ali and Comlekci, Abdurrahman and Caliskan, Sezer},
  title     = {The beneficial effects of lipid-lowering drugs beyond lipid-lowering effects: A comparative study with pravastatin, atorvastatin, and fenofibrate in patients with type IIa and type IIb hyperlipidemia / Saklamaz, Ali ; Comlekci, Abdurrahman ; Temiz, Aysegu},
  series = {Metabolism. 54 (2005), H. 5},
  journal   = {Metabolism. 54 (2005), H. 5},
  isbn      = {0026-0495},
  pages     = {677 -- 681},
  year      = {2005},
  language  = {en}
}
@article{CehreliAkpinarTemizArtmannetal.2015,
  author    = {Cehreli, Ruksan and Akpinar, Hale and Temiz Artmann, Ayseg{\"u}l and Sagol, Ozgul},
  title     = {Effects of Glutamine and Omega-3 Fatty Acids on Erythrocyte Deformability and Oxidative Damage in Rat Model of Enterocolitis},
  series = {Gastroenterology Research},
  volume    = {8},
  journal   = {Gastroenterology Research},
  number    = {5},
  issn      = {1918-2813},
  doi       = {10.14740/gr683w},
  pages     = {265 -- 273},
  year      = {2015},
  language  = {en}
}