@article{BiselliLuellauWandrey1994,
  author    = {Biselli, Manfred and L{\"u}llau, E. and Wandrey, Christian},
  title     = {Growth and metabolism of CHO-cells in porous glass carriers / L{\"u}llau, E. ; Biselli, M. ; Wandrey, C.},
  series = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier},
  journal   = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier},
  publisher = {Butterworth-Heinemann},
  address   = {Oxford},
  isbn      = {0750618450},
  pages     = {252 -- 255},
  year      = {1994},
  language  = {en}
}
@article{BiselliRolefDunkeretal.1994,
  author    = {Biselli, Manfred and Rolef, G. and Dunker, R. and Wandrey, Christian},
  title     = {Optimization of antibody production in a fluidized bed bioreactor / Rolef, G. ; Biselli, M. ; Dunker, R. ; Wandrey, C.},
  series = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier},
  journal   = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier},
  publisher = {Butterworth-Heinemann},
  address   = {Oxford},
  isbn      = {0750618450},
  pages     = {481 -- 484},
  year      = {1994},
  language  = {en}
}
@article{BiselliThoemmesKulaetal.1994,
  author    = {Biselli, Manfred and Th{\"o}mmes, J. and Kula, M.-R. and Wandrey, Christian},
  title     = {Batch kinetic data of hybridoma growth and productivity as a basis for the simulation of antibody production in various culture systems / Th{\"o}mmes, J. ; Biselli, M. ; Kula, M.-R. ; Wandrey, C.},
  series = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier},
  journal   = {Animal cell technology : products of today, prospects for tomorrow ; ESACT, European Society for Animal Cell Technology, the 12th meeting / Ed. R. E. Spier},
  publisher = {Butterworth-Heinemann},
  address   = {Oxford},
  isbn      = {0750618450},
  pages     = {513 -- 517},
  year      = {1994},
  language  = {en}
}
@book{Biselli1992,
  author    = {Biselli, Manfred},
  title     = {Enzymkatalysierte Racematspaltung von Aminos{\"a}uren mit integrierter R{\"u}ckf{\"u}hrung : dargestellt am Beispiel der Umsetzung von D,L-Alanin zu L-Alanin / Manfred Fridolin Biselli},
  publisher = {Forschungszentrum J{\"u}lich, Zentralbibliothek},
  address   = {J{\"u}lich},
  pages     = {VIII, 192 S. : graph. Darst.},
  year      = {1992},
  language  = {de}
}
@book{Biselli1992,
  author    = {Biselli, Manfred},
  title     = {Enzymkatalysierte Racematspaltung von Aminos{\"a}uren mit integrierter R{\"u}ckf{\"u}hrung : dargestellt am Beispiel der Umsetzung von D,L-Alanin zu L-Alanin / vorgelegt von Manfred Fridolin Biselli},
  address   = {Bonn},
  pages     = {VIII, 192 S. : graph. Darst.},
  year      = {1992},
  language  = {de}
}
@article{BiselliVanderPolMachniketal.1997,
  author    = {Biselli, Manfred and Van der Pol, Jens J. and Machnik, Marc and Portela-Klein, Theresa},
  title     = {On-line immunoanalysis of monoclonal antibodies during a continuous culture of hybridoma cells / Jens J. van der Pol, Marc Machnik, Manfred Biselli, Theresa Portela-Klein, Cornelis D. de Gooijer, Johannes Tramper und Christian Wandrey},
  series = {Cytotechnology. 24 (1997), H. 1},
  journal   = {Cytotechnology. 24 (1997), H. 1},
  isbn      = {0920-9069},
  pages     = {19 -- 30},
  year      = {1997},
  language  = {en}
}
@article{BiselliMeissnerSchroederetal.1999,
  author    = {Biselli, Manfred and Meissner, Petra and Schr{\"o}der, Bernd and Herfurth, Cornelia},
  title     = {Development of a fixed bed bioreactor for the expansion of human hematopoietic progenitor cells / Meissner, Petra ; Schr{\"o}der, Bernd ; Herfurth, Cornelia ; Biselli, Manfred},
  series = {Cytotechnology. 30 (1999), H. 1},
  journal   = {Cytotechnology. 30 (1999), H. 1},
  isbn      = {0920-9069},
  pages     = {227 -- 234},
  year      = {1999},
  language  = {en}
}
@article{BiselliSchmidtBuechsetal.1999,
  author    = {Biselli, Manfred and Schmidt, S. and B{\"u}chs, J. and Born, C.},
  title     = {A new correlation for the wall-to-fluid mass transfer in liquid-sol fluidized beds / Schmidt, S. ; B{\"u}chs, J. ; Born, C. ; Biselli, M.},
  series = {Chemical Engineering Science. 54 (1999), H. 6},
  journal   = {Chemical Engineering Science. 54 (1999), H. 6},
  isbn      = {0009-2509},
  pages     = {829 -- 839},
  year      = {1999},
  language  = {en}
}
@article{BiselliHilbertJelineketal.2000,
  author    = {Biselli, Manfred and Hilbert, Ulrike and Jelinek, Nanni and Schmidt, Sebastian},
  title     = {Biotechnologische Aspekte der Kultivierung humaner T-Lymphozyten / Hilbert, Ulrike ; Jelinek, Nanni ; Schmidt, Sebastian ; Biselli, Manfred},
  series = {Chemie Ingenieur Technik. 72 (2000), H. 7},
  journal   = {Chemie Ingenieur Technik. 72 (2000), H. 7},
  isbn      = {1522-2640},
  pages     = {746 -- 750},
  year      = {2000},
  language  = {de}
}
@article{BiselliWandrey1988,
  author    = {Biselli, Manfred and Wandrey, Christian},
  title     = {Reaction Mechanism of an Endoglucanase of Trichoderma Reesei QM 9414 using Cellodextrins as Substrate},
  series = {Technology of biological processes, safety in biotechnology, applied genetic engineering : lectures held at the 5th DECHEMA Annual Meeting of Biotechnologists, May 12 - 13, 1987, [Frankfurt, Main] / [hrsg. von Dieter Behrens ...]},
  journal   = {Technology of biological processes, safety in biotechnology, applied genetic engineering : lectures held at the 5th DECHEMA Annual Meeting of Biotechnologists, May 12 - 13, 1987, [Frankfurt, Main] / [hrsg. von Dieter Behrens ...]},
  publisher = {VCH},
  address   = {Weinheim},
  pages     = {425 -- 429},
  year      = {1988},
  language  = {en}
}
@article{BiselliSchmidWandrey1988,
  author    = {Biselli, Manfred and Schmid, Georg and Wandrey, Christian},
  title     = {Preparation of cellodextrins and isolation of oligomeric side components and their characterization / Schmid, Georg ; Biselli, Manfred ; Wandrey, Christian},
  series = {Analytical Biochemistry. 175 (1988)},
  journal   = {Analytical Biochemistry. 175 (1988)},
  isbn      = {0003-2697},
  pages     = {573 -- 583},
  year      = {1988},
  language  = {en}
}
@article{BiselliThoemmesGarskeetal.1992,
  author    = {Biselli, Manfred and Th{\"o}mmes, J. and Garske, U. and Wandrey, Christian},
  title     = {Integrated detoxification: Reduction of ammonium concentration by dialysis with cation exchange membranes / Th{\"o}mmes, J. ; Garske, U. ; Biselli, M. ; Wandrey, C.},
  series = {Animal cell technology : developments, processes, and products ; ESACT, European Society for Animal Cell Technology, the 11th meeting / Ed. R. E. Spier},
  journal   = {Animal cell technology : developments, processes, and products ; ESACT, European Society for Animal Cell Technology, the 11th meeting / Ed. R. E. Spier},
  publisher = {Butterworth-Heinemann},
  address   = {Oxford},
  isbn      = {0750604212},
  pages     = {171 -- 175},
  year      = {1992},
  language  = {en}
}
@article{WincklerKruegerSchnitzleretal.2014,
  author    = {Winckler, Silvia and Krueger, Rolf and Schnitzler, Thomas and Zang, Werner and Fischer, Rainer and Biselli, Manfred},
  title     = {A sensitive monitoring system for mammalian cell cultivation processes: a PAT approach},
  series = {Bioprocess and biosystems engineering},
  volume    = {37},
  journal   = {Bioprocess and biosystems engineering},
  number    = {5},
  publisher = {Springer},
  address   = {Berlin, Heidelberg},
  issn      = {1615-7591 (Print) 1615-7605 (Online)},
  doi       = {10.1007/s00449-013-1062-8},
  pages     = {901 -- 912},
  year      = {2014},
  abstract  = {Biopharmaceuticals such as antibodies are produced in cultivated mammalian cells, which must be monitored to comply with good manufacturing practice. We, therefore, developed a fully automated system comprising a specific exhaust gas analyzer, inline analytics and a corresponding algorithm to precisely determine the oxygen uptake rate, carbon dioxide evolution rate, carbon dioxide transfer rate, transfer quotient and respiratory quotient without interrupting the ongoing cultivation, in order to assess its reproducibility. The system was verified using chemical simulation experiments and was able to measure the respiratory activity of hybridoma cells and DG44 cells (derived from Chinese hamster ovary cells) with satisfactory results at a minimum viable cell density of ~2.0 × 10⁵ cells ml⁻¹. The system was suitable for both batch and fed-batch cultivations in bubble-aerated and membrane-aerated reactors, with and without the control of pH and dissolved oxygen.},
  language  = {en}
}
@article{SchnitzlerBiselli2005,
  author    = {Schnitzler, Thomas and Biselli, Manfred},
  title     = {Cultivo de lineas celulares de hibridoma por CF-10H5 (DSMZ ACC477) en el BIOSTAT B plus},
  series = {Noticias tecnicas del laboratorio},
  volume    = {13},
  journal   = {Noticias tecnicas del laboratorio},
  number    = {3},
  pages     = {7 -- 8},
  year      = {2005},
  language  = {es}
}
@inproceedings{TakenagaHerreraWerneretal.2013,
  author    = {Takenaga, Shoko and Herrera, Cony F. and Werner, Frederik and Biselli, Manfred and Schnitzler, Thomas and Sch{\"o}ning, Michael Josef and {\"O}hlschl{\"a}ger, Peter and Wagner, Torsten},
  title     = {Detection of the metabolic activity of cells by differential measurements based on a single light-addressable potentiometric sensor chip},
  series = {11. Dresdner Sensor-Symposium : 9.-11.12.2013},
  booktitle = {11. Dresdner Sensor-Symposium : 9.-11.12.2013},
  organization    = {Dresdner Sensor-Symposium <11, 2013>},
  isbn      = {978-3-9813484-5-3},
  pages     = {63 -- 67},
  year      = {2013},
  language  = {en}
}
@article{TakenagaBiselliSchnitzleretal.2014,
  author    = {Takenaga, Shoko and Biselli, Manfred and Schnitzler, Thomas and {\"O}hlschl{\"a}ger, Peter and Wagner, Torsten and Sch{\"o}ning, Michael Josef},
  title     = {Toward multi-analyte bioarray sensors: LAPS-based on-chip determination of a Michaelis-Menten-like kinetics for cell culturing},
  series = {Physica status solidi A : Applications and materials science},
  volume    = {211},
  journal   = {Physica status solidi A : Applications and materials science},
  number    = {6},
  publisher = {Wiley-VCH},
  address   = {Weinheim},
  issn      = {1521-396X (E); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)},
  doi       = {10.1002/pssa.201330464},
  pages     = {1410 -- 1415},
  year      = {2014},
  abstract  = {The metabolic activity of Chinese hamster ovary (CHO) cells was observed using a light-addressable potentiometric sensor (LAPS). The dependency toward different glucose concentrations (17-200 mM) follows a Michaelis-Menten kinetics trajectory with Kₘ = 32.8 mM, and the obtained Kₘ value in this experiment was compared with that found in literature. In addition, the pH shift induced by glucose metabolism of tumor cells transfected with the HPV-16 genome (C3 cells) was successfully observed. These results indicate the possibility to determine the tumor cells metabolism with a LAPS-based measurement device.},
  language  = {en}
}
@article{TakenagaSchneiderErbayetal.2015,
  author    = {Takenaga, Shoko and Schneider, Benno and Erbay, E. and Biselli, Manfred and Schnitzler, Thomas and Sch{\"o}ning, Michael Josef and Wagner, Torsten},
  title     = {Fabrication of biocompatible lab-on-chip devices for biomedical applications by means of a 3D-printing process},
  series = {Physica status solidi (a)},
  volume    = {212},
  journal   = {Physica status solidi (a)},
  number    = {6},
  publisher = {Wiley},
  address   = {Weinheim},
  issn      = {1862-6319},
  doi       = {10.1002/pssa.201532053},
  pages     = {1347 -- 1352},
  year      = {2015},
  abstract  = {A new microfluidic assembly method for semiconductor-based biosensors using 3D-printing technologies was proposed for a rapid and cost-efficient design of new sensor systems. The microfluidic unit is designed and printed by a 3D-printer in just a few hours and assembled on a light-addressable potentiometric sensor (LAPS) chip using a photo resin. The cell growth curves obtained from culturing cells within microfluidics-based LAPS systems were compared with cell growth curves in cell culture flasks to examine biocompatibility of the 3D-printed chips. Furthermore, an optimal cell culturing within microfluidics-based LAPS chips was achieved by adjusting the fetal calf serum concentrations of the cell culture medium, an important factor for the cell proliferation.},
  language  = {en}
}
@article{BaeckerPouyeshmanSchnitzleretal.2011,
  author    = {B{\"a}cker, Matthias and Pouyeshman, S. and Schnitzler, Thomas and Poghossian, Arshak and Wagner, Patrick and Biselli, Manfred and Sch{\"o}ning, Michael Josef},
  title     = {A silicon-based multi-sensor chip for monitoring of fermentation processes},
  series = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6},
  journal   = {Physica status solidi (a) : applications and material science. 208 (2011), H. 6},
  publisher = {Wiley},
  address   = {Weinheim},
  isbn      = {1862-6319},
  pages     = {1364 -- 1369},
  year      = {2011},
  language  = {en}
}
@misc{WandreyBiselliSchroederetal.1999,
  author    = {Wandrey, Christian and Biselli, Manfred and Schr{\"o}der, Bernd and Schmoll, Hans-Joachim},
  title     = {Culturing cells on macroporous glass carriers coated with gelatin, extracellular matrix protein and stromal cells},
  pages     = {1 -- 12},
  year      = {1999},
  language  = {en}
}
@misc{BiselliThoemmesWandrey1991,
  author    = {Biselli, Manfred and Th{\"o}mmes, J{\"o}rg and Wandrey, Christian},
  title     = {Verfahren und Vorrichtung zur Abtrennung von Ammonium aus w{\"a}ßrigen Fl{\"u}ssigkeiten [Europ{\"a}ische Patentanmeldung]},
  pages     = {1 -- 12},
  year      = {1991},
  language  = {de}
}